Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.9;kidney: 133.3;liver: 345.6;pancreas: 138.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.3;Horizontal cells: 68.6;Inhibitory neurons: 92.8;Oligodendrocyte precursor cells: 73.6;Proximal tubular cells: 76.7" "Cancer enhanced" "Detected in all" "glioma: 27.3;liver cancer: 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 29: Hepatocytes - Metabolism" Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favorable (5.36e-5)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favorable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 48.7;Early spermatids: 87.4;Late spermatids: 76.8;Leydig cells: 50.6;Peritubular cells: 51.5;Prostatic glandular cells: 94.8" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.1;Rhabdoid: 2.3;testis cancer: 2.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 73: Prostatic glandular cells - Transcription" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 77.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 282.6;Inhibitory neurons: 298.1;Oligodendrocyte precursor cells: 176.2;Oligodendrocytes: 118.6" "Cancer enhanced" "Detected in many" "glioma: 4.0" "Region enhanced" "Detected in all" "cerebellum: 77.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 31.7" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" "Intracellular and membrane" NA NA 180000 "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" "Cell Junctions" "CAB079064: , HPA050325: AB_2681087" "unprognostic (1.20e-2)" "unprognostic (8.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.89e-2)" "unprognostic (3.09e-1)" "unprognostic (7.84e-3)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-1)" "unprognostic (3.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-4)" "unprognostic (4.70e-2)" ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;lymphoid tissue: 10.9" "Group enriched" "Detected in some" 15 "granulocytes: 331.1;Pancreatic endocrine cells: 92.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 17.4;Rhabdoid: 19.9;thyroid cancer: 10.4" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 46: Granulocytes - Mast cell degranulation" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;brain: 101.4;lymphoid tissue: 54.1" "Cell type enhanced" "Detected in some" "B-cells: 6.2;Gastric mucus-secreting cells: 1.8;Plasma cells: 10.5;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 101.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 44.1;Myeloma: 41.0" "Kidney - Endothelial cells" "Region enriched" "Detected in many" 9 "basal ganglia: 399.8" "Region enriched" "Detected in many" 50 "basal ganglia: 142.2" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 102.2;Early spermatids: 31.6;Inhibitory neurons: 120.0;Late spermatids: 38.8;Oligodendrocyte precursor cells: 109.3" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 4.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 37: Neurons - Neuronal signaling" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483547 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 122.5;epididymis: 37.1" "Cell type enhanced" "Detected in some" "Distal tubular cells: 6.2;Hofbauer cells: 8.1;Leydig cells: 3.1;Macrophages: 5.2;Peritubular cells: 2.8;Respiratory ciliated cells: 2.0;Theca cells: 3.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in many" 60 "hypothalamus: 122.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Leukemia: 1.1;lymphoma: 1.0" "Lung - Macrophages" "Region enriched" "Detected in single" 16 "hypothalamus: 16.0" "Region enhanced" "Detected in single" "hypothalamus: 2.0" HPA041017 Enhanced Supported "Secreted in brain" NA NA 255000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA041017: AB_10795498" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (3.61e-1)" "unprognostic (3.34e-1)" "unprognostic (4.68e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (3.17e-1)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-2)" AKAP5 "AKAP75, AKAP79" ENSG00000179841 "A-kinase anchoring protein 5" P24588 14 64465499-64474503 "Plasma proteins, Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 13.5;intestine: 3.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.0;granulocytes: 37.8;Intestinal goblet cells: 31.6;NK-cells: 22.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 29 "amygdala: 5.3;basal ganglia: 13.5;cerebral cortex: 8.5;hippocampal formation: 7.7" "Immune cell enriched" "Detected in single" 8 "basophil: 3.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "amygdala: 27.6;basal ganglia: 79.0;cerebral cortex: 29.4;hippocampal formation: 30.8" "Group enriched" "Detected in all" 5 "amygdala: 24.3;basal ganglia: 79.9;cerebral cortex: 44.9;hippocampal formation: 43.7" "CAB004308, HPA053891" Enhanced Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "CAB004308: AB_626655, HPA053891: AB_2682294" "unprognostic (4.29e-2)" "unprognostic (5.89e-3)" "unprognostic (3.44e-4)" "unprognostic (2.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.24e-3)" "unprognostic (1.08e-1)" "unprognostic (3.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.02e-3)" "unprognostic (8.23e-2)" "unprognostic (1.42e-1)" "unprognostic (5.44e-2)" "unprognostic (4.49e-4)" "unprognostic (2.11e-1)" "unprognostic (2.42e-1)" "unprognostic (7.45e-2)" ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 667.2;Leydig cells: 411.1;Proximal tubular cells: 388.8;Respiratory ciliated cells: 489.4" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cancer enhanced" "Detected in many" "liver cancer: 1072.2;Rhabdoid: 926.6;Sarcoma: 887.0" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Hepatocytes: 550.1;Proximal tubular cells: 166.9;Serous glandular cells: 92.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 18.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 144.1;Cone photoreceptor cells: 324.0;Horizontal cells: 173.0;Proximal enterocytes: 129.2;Rod photoreceptor cells: 247.6" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 68: Kidney - Mixed function" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 195.6;Cone photoreceptor cells: 55.1;Erythroid cells: 169.1;Horizontal cells: 85.9;Inhibitory neurons: 173.2;Skeletal myocytes: 223.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Cancer enhanced" "Detected in many" "Leukemia: 42.9;Sarcoma: 29.4" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Erythroid cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Cell type enhanced" "Detected in many" "Astrocytes: 1066.9;Excitatory neurons: 1263.4;Horizontal cells: 536.4;Inhibitory neurons: 1036.9;Oligodendrocyte precursor cells: 476.1;Oligodendrocytes: 1275.4;Rod photoreceptor cells: 487.6" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.2;Rhabdoid: 33.5" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" AP3B2 NAPTB ENSG00000103723 "Adaptor related protein complex 3 subunit beta 2" Q13367 15 82659281-82710112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.7;pituitary gland: 18.8;retina: 33.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 25.8;Excitatory neurons: 60.8;Horizontal cells: 28.8;Inhibitory neurons: 55.6;Oligodendrocyte precursor cells: 42.8;Rod photoreceptor cells: 78.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 22.3" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039467, HPA039818" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039467: AB_10795143, HPA039818: AB_10795299" "unprognostic (3.17e-1)" "unprognostic (9.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.48e-6)" "unprognostic (8.44e-2)" "unprognostic (7.62e-2)" "unprognostic (5.82e-2)" "unprognostic (2.32e-1)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (3.57e-3)" "unprognostic (1.12e-1)" "unprognostic (8.66e-2)" "unprognostic (4.95e-2)" "unprognostic (3.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.43e-2)" AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Group enriched" "Detected in some" 11 "Alveolar cells type 1: 427.4;Alveolar cells type 2: 326.1;Astrocytes: 472.6;Muller glia cells: 200.5" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 3.0;Rhabdoid: 1.7" "Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 41: Alveolar cells - Lung function" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" ARC "Arg3.1, KIAA0278" ENSG00000198576 "Activity regulated cytoskeleton associated protein" Q7LC44 8 142611049-142614479 "Predicted intracellular proteins" "Endocytosis, Transport" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 122.9;pituitary gland: 67.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 82.9;Breast glandular cells: 33.7;Breast myoepithelial cells: 64.3;Endometrial stromal cells: 48.6;Enteroendocrine cells: 61.5" "Cancer enriched" "Detected in many" 12 "glioma: 36.1" "Group enriched" "Detected in all" 6 "cerebral cortex: 122.9;hippocampal formation: 34.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bone cancer: 9.7;Neuroblastoma: 22.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basal ganglia: 20.7;cerebral cortex: 75.1;hippocampal formation: 42.4;olfactory bulb: 22.9" "HPA056430, CAB079013" Supported Approved Vesicles,Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 11: Non-specific - Transcription" "Vesicles, Microtubules" "CAB079013: , HPA056430: AB_2683130" "unprognostic (1.40e-3)" "unprognostic (2.95e-2)" "unprognostic (4.35e-3)" "unprognostic (4.87e-4)" "unprognostic (6.83e-2)" "unprognostic (8.12e-2)" "unprognostic (5.13e-2)" "unprognostic (1.77e-1)" "unprognostic (5.07e-2)" "unprognostic (9.43e-2)" "unprognostic (4.15e-3)" "unprognostic (1.40e-1)" "unprognostic (2.14e-2)" "unprognostic (1.01e-2)" "unprognostic (7.42e-2)" "unprognostic (1.54e-1)" "unprognostic (3.35e-2)" ARFGEF1 "ARFGEP1, BIG1, DKFZP434L057, p200" ENSG00000066777 "ADP ribosylation factor guanine nucleotide exchange factor 1" Q9Y6D6 8 67173511-67343781 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023399, HPA023822" Supported Supported Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Chromatin organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA023399: AB_1844981, HPA023822: AB_1844982" "prognostic unfavorable (8.76e-4)" "unprognostic (1.62e-1)" "unprognostic (4.60e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (4.52e-1)" "unprognostic (5.38e-2)" "unprognostic (4.67e-2)" "unprognostic (2.13e-3)" "unprognostic (1.31e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" ARPP21 "ARPP-21, R3HDM3, TARPP" ENSG00000172995 "CAMP regulated phosphoprotein 21" Q9UBL0 3 35638945-35794496 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 260.8;lymphoid tissue: 170.1;skeletal muscle: 85.6" "Group enriched" "Detected in some" 5 "Excitatory neurons: 849.0;Oligodendrocyte precursor cells: 598.3;Skeletal myocytes: 260.3" "Cancer enriched" "Detected in single" 5 "glioma: 1.3" "Region enhanced" "Detected in many" "basal ganglia: 260.8" "Immune cell enriched" "Detected in single" 30 "plasmacytoid DC: 10.1" "Lineage enriched" "Detected in single" 30 "dendritic cells: 10.1" "Cancer enriched" "Detected in some" 8 "Leukemia: 41.3" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 254.3" HPA017303 Enhanced Supported Approved Nucleoli,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" Nucleoli Cytosol "HPA017303: AB_1845049" "unprognostic (1.72e-4)" "unprognostic (2.35e-1)" "unprognostic (1.10e-2)" "unprognostic (6.61e-2)" "unprognostic (6.30e-3)" "unprognostic (8.90e-2)" "unprognostic (2.42e-3)" "unprognostic (1.27e-1)" "unprognostic (7.42e-4)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "unprognostic (1.52e-1)" ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 167.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "CAB003769: AB_562241, HPA022134: AB_1845138" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-1)" "unprognostic (9.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.28e-2)" "unprognostic (3.70e-2)" "unprognostic (6.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.02e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (7.21e-3)" "unprognostic (6.70e-2)" ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease variant, Dystonia, Epilepsy, Intellectual disability, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 645.2;heart muscle: 157.7;retina: 292.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 399.4;Cone photoreceptor cells: 249.9;Horizontal cells: 323.6;Inhibitory neurons: 116.4;Late spermatids: 97.3;Rod photoreceptor cells: 250.0" "Cancer enriched" "Detected in many" 5 "glioma: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 66.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA 220000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "CAB033630: AB_781528, HPA045367: AB_2679297, HPA056446: AB_2683136" "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavorable (3.44e-4)" "prognostic favorable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 770.2;Langerhans cells: 527.6;monocytes: 496.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 187.9" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 7.0;Excitatory neurons: 23.3;Extravillous trophoblasts: 12.9;Horizontal cells: 23.1;Inhibitory neurons: 29.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.3;Neuroblastoma: 8.8" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 12: Non-specific - Chromatin organization" "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Host-virus interaction" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1308 "brain: 7951.2" "Group enriched" "Detected in some" 7 "dendritic cells: 14.0;Late spermatids: 26.1;Proximal tubular cells: 45.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 131 "hypothalamus: 7951.2" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cancer enriched" "Detected in single" 131 "Leukemia: 13.8" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "hypothalamus: 232.9" "Group enriched" "Detected in many" 337 "basal ganglia: 815.6;hypothalamus: 743.3" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" NA NA 19300 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 60: Proximal tubular cells - Absorption" "CAB025318: , HPA071892: AB_2732190" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" BAIAP3 "BAP3, KIAA0734" ENSG00000007516 "BAI1 associated protein 3" O94812 16 1333638-1349441 "Predicted intracellular proteins" "Exocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 221.6;pituitary gland: 367.9" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Endometrial ciliated cells: 22.3;Enteroendocrine cells: 36.4;Excitatory neurons: 19.0;Respiratory ciliated cells: 53.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in many" "hypothalamus: 123.4" "Low region specificity" "Detected in all" "HPA015627, HPA015979" Uncertain Supported NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: DU4475 - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA015627: AB_10603678, HPA015979: " "unprognostic (1.37e-2)" "unprognostic (3.93e-2)" "unprognostic (2.44e-2)" "unprognostic (3.92e-3)" "unprognostic (4.43e-2)" "unprognostic (1.10e-1)" "unprognostic (2.25e-1)" "unprognostic (1.06e-1)" "unprognostic (5.60e-2)" "unprognostic (6.75e-3)" "unprognostic (1.44e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.52e-5)" "unprognostic (5.26e-2)" "unprognostic (3.11e-1)" "unprognostic (7.12e-3)" "unprognostic (6.43e-2)" BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1516.2" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 9.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 164.7" "Group enriched" "Detected in some" 4 "Astrocytes: 131.9;Melanocytes: 275.2;Oligodendrocyte precursor cells: 275.8" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Low cancer specificity" "Detected in all" "Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" NA NA 120000 "Cluster 34: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 567.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 48: Non-specific - RNA binding" "Cluster 19: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282, HPA063796" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 36: Non-specific - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929, HPA063796: " "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.8;Basal squamous epithelial cells: 90.5;Inhibitory neurons: 103.1;NK-cells: 137.8;Suprabasal keratinocytes: 77.0;T-cells: 295.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "Bone cancer: 18.1;Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.0;lymphoid tissue: 141.5" "Cell type enhanced" "Detected in many" "granulocytes: 737.3;Langerhans cells: 1603.7;monocytes: 693.9;Proximal enterocytes: 883.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 209.0;naive B-cell: 159.9" "Group enriched" "Detected in all" 13 "B-cells: 209.0;T-cells: 83.6" "Cancer enhanced" "Detected in many" "lymphoma: 122.5" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" C17orf75 "NJMU-R1, SRI2" ENSG00000108666 "Chromosome 17 open reading frame 75" Q9HAS0 17 32324565-32350023 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004061, HPA075333" Approved Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 46: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" "Golgi apparatus, Cytosol" "HPA004061: AB_1078337, HPA075333: " "unprognostic (4.21e-2)" "unprognostic (2.49e-2)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (1.51e-1)" "unprognostic (4.73e-2)" "unprognostic (1.07e-3)" "unprognostic (6.36e-2)" "unprognostic (3.29e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.92e-2)" "unprognostic (7.80e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.09e-1)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (5.60e-2)" C5orf63 "FLJ44606, YDR286C" ENSG00000164241 "Chromosome 5 open reading frame 63" A6NC05 5 127042558-127073492 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 43 "brain: 760.0;choroid plexus: 360.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 49.4;Spermatocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043240 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 52: Spermatids - Smell perception" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043240: AB_10962511" "unprognostic (2.71e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (2.94e-4)" "unprognostic (1.34e-1)" "unprognostic (9.67e-2)" "unprognostic (3.40e-2)" "unprognostic (1.43e-4)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 99.3" "Group enriched" "Detected in many" 8 "Bipolar cells: 148.0;Enteroendocrine cells: 232.2;Excitatory neurons: 313.9;Horizontal cells: 437.7;Inhibitory neurons: 363.4;Oligodendrocyte precursor cells: 260.4" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in all" 4 "cerebellum: 99.3;cerebral cortex: 30.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 8.0;Rhabdoid: 8.0" "Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970786-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 20.7;heart muscle: 27.1;intestine: 29.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 598.2;Inhibitory neurons: 465.5;Oligodendrocyte precursor cells: 186.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.9" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 185.8;Inhibitory neurons: 112.9;Oligodendrocyte precursor cells: 70.8;Oligodendrocytes: 32.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.9;lymphoma: 1.8;prostate cancer: 2.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 2: DU4475 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.3;Excitatory neurons: 35.0;Horizontal cells: 56.4;Inhibitory neurons: 39.5;Melanocytes: 64.4;Muller glia cells: 32.5;Schwann cells: 89.8" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 54.1;skin cancer: 22.2" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 666.1;Cone photoreceptor cells: 305.0;Excitatory neurons: 817.6;Horizontal cells: 239.7;Inhibitory neurons: 1128.7;Oligodendrocyte precursor cells: 255.6" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.0" "Colon - Colon enteroendocrine cells, Lung - Mast cells, Skin - Fibroblast_2" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Group enriched" "Detected in many" 5 "granulocytes: 129.0;Thymic epithelial cells: 489.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 39.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Mast cells, Stomach - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 46: Granulocytes - Mast cell degranulation" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966668-14972351 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 178.3;thyroid gland: 154.2" "Cell type enriched" "Detected in some" 15 "Ionocytes: 377.3" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "thyroid cancer: 2248.9" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Region enriched" "Detected in all" 5 "pons and medulla: 57.9" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" NA NA 51500 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 5: Bronchus - Unknown function" "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.9;thyroid gland: 20.7" "Cell type enhanced" "Detected in some" "Melanocytes: 3.5;Respiratory ciliated cells: 1.2;Spermatocytes: 1.7;Spermatogonia: 4.4;T-cells: 1.2" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Group enriched" "Detected in many" 4 "hypothalamus: 6.8;medulla oblongata: 8.9;midbrain: 11.6;pons: 18.9;white matter: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 23.1;colorectal cancer: 64.7;thyroid cancer: 60.6" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 30.4;basal ganglia: 74.3;hypothalamus: 50.1;midbrain: 33.9;pons: 41.7" HPA059886 Supported "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 2: T-cells - T-cell receptor" "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" CALCR CTR ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;kidney: 1.5" "Group enriched" "Detected in some" 5 "Early spermatids: 16.9;Late spermatids: 9.4;Microglial cells: 15.5" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.9;Uterine cancer: 3.0" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 11: Non-specific - Transcription" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 708.3" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "prostate cancer: 11.2" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 35: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237675-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.9;Late spermatids: 90.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 32.7;eosinophil: 62.1;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.2;non-classical monocyte: 39.5" "Group enriched" "Detected in all" 5 "dendritic cells: 15.9;granulocytes: 62.1;monocytes: 42.3" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49869935 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 91.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 32.2;Horizontal cells: 42.3;Inhibitory neurons: 26.3;Late spermatids: 9.4" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 23.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 514.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 2800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 118.6;brain: 183.6" "Cell type enhanced" "Detected in some" "Early spermatids: 35.7;Horizontal cells: 144.2;Spermatocytes: 45.0" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 6.9;Rhabdoid: 2.2" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 209.0" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.14e-1)" CASKIN1 "ANKS5A, KIAA1306" ENSG00000167971 "CASK interacting protein 1" Q8WXD9 16 2177180-2196605 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 45.8" "Group enriched" "Detected in some" 5 "Astrocytes: 38.3;Bipolar cells: 22.0;Excitatory neurons: 20.5;Horizontal cells: 44.2;Inhibitory neurons: 25.8;Muller glia cells: 18.9;Oligodendrocyte precursor cells: 27.4" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055990, HPA076882, CAB079050" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 9: Neurons - Nervous system development" Nucleoplasm Cytosol "CAB079050: , HPA055990: AB_2682997, HPA076882: " "unprognostic (4.91e-2)" "unprognostic (2.48e-1)" "unprognostic (4.84e-2)" "unprognostic (1.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.05e-1)" "unprognostic (2.80e-2)" "unprognostic (8.02e-2)" "unprognostic (6.58e-2)" "unprognostic (4.59e-1)" "unprognostic (2.21e-4)" "unprognostic (2.67e-2)" "unprognostic (2.62e-1)" "unprognostic (9.70e-3)" "unprognostic (1.72e-1)" "unprognostic (7.34e-3)" "unprognostic (3.39e-1)" CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 4.1;Theca cells: 4.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.1" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.8;brain: 19.3;epididymis: 8.8" "Group enriched" "Detected in some" 6 "Excitatory neurons: 26.6;Inhibitory neurons: 30.6;Peritubular cells: 36.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" NA NA 10000000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 32: Neurons - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 87.6;retina: 52.5;testis: 185.7" "Group enriched" "Detected in many" 4 "Early spermatids: 724.5;Late spermatids: 1987.4" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 26.1" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 51: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" CCDC22 "CXorf37, JM1" ENSG00000101997 "Coiled-coil domain containing 22" O60826 X 49235470-49250520 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000229, HPA000888, HPA075980" Uncertain Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 19: Macrophages - Innate immune response" "Endoplasmic reticulum, Vesicles" "HPA000229: , HPA000888: AB_1078420, HPA075980: " "unprognostic (1.24e-2)" "unprognostic (1.96e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.70e-1)" "unprognostic (4.57e-3)" "unprognostic (3.61e-2)" "unprognostic (4.99e-2)" "unprognostic (6.99e-2)" "unprognostic (2.57e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-3)" CCK ENSG00000187094 Cholecystokinin P06307 3 42257825-42266185 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 317.9;choroid plexus: 89.5;intestine: 115.7" "Cell type enhanced" "Detected in some" "Astrocytes: 38.9;Enteroendocrine cells: 117.4;Excitatory neurons: 152.6;Inhibitory neurons: 154.1;Melanocytes: 38.3;Oligodendrocytes: 38.6" "Group enriched" "Detected in many" 5 "glioma: 4.0;pancreatic cancer: 1.8;prostate cancer: 3.5;stomach cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bone cancer: 89.0;Gastric cancer: 52.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 74.4" "HPA045039, HPA069515" Enhanced Supported "Secreted to blood" NA NA 43700000 "Cluster 10: Brain - Neuronal signaling" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" "HPA045039: , HPA069515: AB_2732135" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.39e-3)" "unprognostic (1.97e-2)" "unprognostic (3.91e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (1.37e-1)" "unprognostic (5.10e-2)" CCSAP "C1orf96, CSAP, FLJ41471" ENSG00000154429 "Centriole, cilia and spindle associated protein" Q6IQ19 1 229321011-229343294 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.3;retina: 25.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.9;Syncytiotrophoblasts: 140.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028402, HPA043443" Enhanced Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 6: BEWO - Unknown function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA028402: AB_10603681, HPA043443: AB_2678485" "unprognostic (4.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (2.63e-1)" "unprognostic (1.18e-1)" "unprognostic (3.26e-1)" "unprognostic (4.97e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (4.50e-13)" "unprognostic (9.67e-2)" "unprognostic (4.93e-1)" "unprognostic (4.15e-2)" "unprognostic (1.03e-1)" CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 185.2;Muller glia cells: 516.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 68: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 24.4;skeletal muscle: 57.0" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 67.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 15 "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Sarcoma: 32.2" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 17 "cerebellum: 18.7" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 11: Non-specific - Transcription" "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" CDH22 "C20orf25, dJ998H6.1" ENSG00000149654 "Cadherin 22" Q9UJ99 20 46173739-46308498 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.5" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 47.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "amygdala: 10.7;basal ganglia: 5.0;cerebellum: 19.5;cerebral cortex: 15.2;hippocampal formation: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.0" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA012164, HPA012715" Uncertain Supported NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 38: Neurons - Neuronal signaling" "HPA012164: AB_1845902, HPA012715: " "unprognostic (2.41e-4)" "unprognostic (1.72e-2)" "unprognostic (3.10e-1)" "unprognostic (4.32e-3)" "unprognostic (3.39e-2)" "unprognostic (4.73e-1)" "unprognostic (4.32e-1)" "unprognostic (2.54e-2)" "unprognostic (5.54e-2)" "unprognostic (4.50e-4)" "unprognostic (2.62e-1)" "unprognostic (3.09e-1)" "unprognostic (7.26e-3)" "unprognostic (5.93e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (9.83e-2)" CELF5 BRUNOL5 ENSG00000161082 "CUGBP Elav-like family member 5" Q8N6W0 19 3224661-3297076 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 75.8;Excitatory neurons: 87.4;Horizontal cells: 66.0;Inhibitory neurons: 71.0" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.5" "Colon - Colon enteroendocrine cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042012, HPA060336" Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "HPA042012: AB_10796896, HPA060336: AB_2684256" "unprognostic (1.09e-1)" "unprognostic (9.24e-2)" "unprognostic (9.25e-3)" "unprognostic (3.48e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (1.35e-1)" "unprognostic (4.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.74e-3)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" "unprognostic (1.25e-1)" "unprognostic (8.07e-2)" CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 83.2;Excitatory neurons: 42.4;Horizontal cells: 96.8;Inhibitory neurons: 44.6" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.4;Rhabdoid: 26.2" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" CHAT ENSG00000070748 "Choline O-acetyltransferase" P28329 10 49609095-49667942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Acyltransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 13.0;placenta: 5.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.4;Horizontal cells: 3.8;Late spermatids: 1.5;Smooth muscle cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bone cancer: 4.0;Neuroblastoma: 5.7" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in many" "basal ganglia: 20.6" "Group enriched" "Detected in some" 7 "basal ganglia: 6.5;pons: 7.0;spinal cord: 12.0" "CAB002313, HPA048547, CAB079053" Supported Supported NA NA "Cluster 65: Brain - Ion transport" "Cluster 56: Neurons - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB002313: AB_563661, CAB079053: , HPA048547: AB_2680437" "unprognostic (2.34e-2)" "unprognostic (6.10e-2)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (2.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.09e-1)" CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 1209.9;Pancreatic endocrine cells: 647.5" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Gastric cancer: 82.4;lung cancer: 62.8;Neuroblastoma: 219.3;thyroid cancer: 189.6" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Testis - Spermatocytes, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enriched" "Detected in some" 5 "Prostatic glandular cells: 49.8" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 2.8;Neuroblastoma: 8.6;prostate cancer: 2.4" "Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 73: Prostatic glandular cells - Transcription" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;retina: 37.9;skeletal muscle: 45.0;tongue: 34.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 75.2;Cone photoreceptor cells: 144.8;Excitatory neurons: 45.0;Horizontal cells: 59.0;Inhibitory neurons: 52.7;Oligodendrocytes: 72.3;Rod photoreceptor cells: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 44: Photoreceptor cells - Visual perception" Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.7;intestine: 4.2;pituitary gland: 10.1;retina: 5.9" "Cell type enriched" "Detected in some" 11 "Cone photoreceptor cells: 34.5" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 2.5" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 44: Photoreceptor cells - Visual perception" "CAB079025: , HPA049378: AB_2732551" "unprognostic (2.34e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-2)" "unprognostic (4.81e-2)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.17e-4)" "unprognostic (4.65e-2)" "unprognostic (1.86e-3)" "unprognostic (2.88e-1)" "unprognostic (3.85e-3)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.71e-2)" CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966763-41977740 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1395.7" "Group enriched" "Detected in all" 4 "Oligodendrocytes: 524.4;Schwann cells: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 149.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "white matter: 1789.4" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 46000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 20.6;Excitatory neurons: 44.0;Inhibitory neurons: 196.1;Sertoli cells: 49.8;Smooth muscle cells: 21.1" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 18.0;lymphoma: 24.3" "Breast - Adipocytes (Breast), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 740.2;Excitatory neurons: 832.7;Inhibitory neurons: 682.3;Oligodendrocyte precursor cells: 978.1" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 239.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Bipolar cells: 39.4;Excitatory neurons: 95.3;Inhibitory neurons: 48.9;Oligodendrocytes: 138.2" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Endothelial cells, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" CPLX3 CPX-III ENSG00000213578 "Complexin 3" Q8WVH0 15 74826627-74831802 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 44.2;lymphoid tissue: 110.3;prostate: 122.4;retina: 98.6" "Group enriched" "Detected in some" 5 "Astrocytes: 2.5;Cone photoreceptor cells: 1.7;Inhibitory neurons: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Uterine cancer: 31.2" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB079003 Supported NA NA "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 32: Neurons - Synaptic function" "CAB079003: " CRABP1 "CRABP, CRABP-I, CRABPI, RBP5" ENSG00000166426 "Cellular retinoic acid binding protein 1" P29762 15 78340353-78348225 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 544.1;thyroid gland: 173.2" "Cell type enriched" "Detected in some" 15 "Muller glia cells: 4719.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 117.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 89.5;breast cancer: 54.5;Neuroblastoma: 179.0" "Colon - Colon enteroendocrine cells, Thyroid - Thyroid glandular cells" "Group enriched" "Detected in many" 5 "amygdala: 6.4;basal ganglia: 23.4;hypothalamus: 13.3;olfactory bulb: 12.8;pons and medulla: 7.4" "Low region specificity" "Detected in all" HPA017203 Enhanced Supported NA NA "Cluster 77: Retina - Visual perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 68: Muller glia cells - Visual perception" "HPA017203: AB_1846512" "unprognostic (1.23e-1)" "unprognostic (3.76e-3)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (2.01e-1)" "unprognostic (4.35e-2)" "unprognostic (1.05e-1)" "unprognostic (1.35e-1)" "unprognostic (2.45e-2)" "unprognostic (9.79e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (9.37e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (2.69e-1)" CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.9;choroid plexus: 14.1;retina: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 39.2;Bipolar cells: 37.4;Cone photoreceptor cells: 63.8;Oligodendrocytes: 25.4;Rod photoreceptor cells: 108.8;Thymic epithelial cells: 27.9" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.2" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043674 Approved Supported "Intracellular and membrane" NA NA 210000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 44: Photoreceptor cells - Visual perception" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Cell type enhanced" "Detected in some" "Adipocytes: 104.1;Endothelial cells: 76.6;Fibroblasts: 199.8;Granulosa cells: 439.7;Kupffer cells: 91.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Brain cancer: 14.3" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.3" "Cell type enhanced" "Detected in all" "B-cells: 130.9;Kupffer cells: 106.7;monocytes: 185.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" CTBP2 ribeye ENSG00000175029 "C-terminal binding protein 2" P56545 10 124984317-125161170 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023559, HPA023564, CAB031916, HPA044971, CAB079018" Approved Approved Approved Nucleoplasm NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB031916: AB_2086774, CAB079018: , HPA023559: AB_1847309, HPA023564: AB_1847310, HPA044971: AB_2679161" "unprognostic (8.69e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-2)" "unprognostic (1.41e-2)" "unprognostic (6.84e-3)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (5.60e-3)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (3.24e-2)" "unprognostic (3.99e-3)" "prognostic favorable (1.70e-4)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (1.62e-1)" CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Fibroblasts: 75.3;Leydig cells: 89.1;Melanocytes: 102.8;Sertoli cells: 41.5;Smooth muscle cells: 69.9" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Neuroblastoma: 93.0;skin cancer: 107.6" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 65: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4;placenta: 12.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 54.3;Syncytiotrophoblasts: 203.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Bone cancer: 27.1" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 16.9;cerebral cortex: 21.4;hippocampal formation: 16.8" HPA030251 Enhanced Supported NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA030251: AB_10611108" "unprognostic (5.22e-6)" "unprognostic (3.13e-2)" "unprognostic (1.04e-2)" "prognostic favorable (1.07e-5)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-3)" "unprognostic (2.48e-1)" "prognostic favorable (5.76e-5)" "unprognostic (1.51e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-4)" "unprognostic (4.23e-2)" DAGLA "C11orf11, DAGLALPHA, KIAA0659, NSDDR" ENSG00000134780 "Diacylglycerol lipase alpha" Q9Y4D2 11 61680391-61747001 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Cell type enhanced" "Detected in many" "Astrocytes: 12.3;Excitatory neurons: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062497, CAB078793" Approved Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 26: Intestinal epithelial cells - Absorption" "CAB078793: , HPA062497: AB_2684784" "unprognostic (2.53e-3)" "unprognostic (1.85e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (1.23e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-4)" "unprognostic (2.22e-2)" "unprognostic (2.29e-3)" "unprognostic (3.99e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.14e-2)" DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 82.1;Exocrine glandular cells: 71.6;Fibroblasts: 70.5;Pancreatic endocrine cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078445-150257438 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.0" "Group enriched" "Detected in many" 4 "Astrocytes: 485.5;Excitatory neurons: 187.0;Inhibitory neurons: 169.3;Oligodendrocyte precursor cells: 165.1" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.3" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.25e-4)" "prognostic favorable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;endometrium 1: 1.4;retina: 2.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 38.5;Inhibitory neurons: 88.2;Oligodendrocyte precursor cells: 47.7;Rod photoreceptor cells: 20.1" "Cancer enriched" "Detected in some" 5 "glioma: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "Neuroblastoma: 29.1" "Pancreas - Beta cells, Skin - Fibroblast_1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 4 "olfactory bulb: 68.6" HPA036121 Enhanced Supported Approved Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA036121: AB_2674950" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (7.36e-2)" "unprognostic (4.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-2)" "unprognostic (7.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.33e-3)" "unprognostic (3.67e-1)" "unprognostic (4.90e-4)" "unprognostic (5.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 906.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 260000 "Cluster 18: Basophils - Vesicular transport" "Cluster 52: Non-specific - Ribosome" "Cluster 48: Non-specific - RNA binding" "Cluster 11: Non-specific - Transcription" Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3 Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 96.0" "Cell type enhanced" "Detected in many" "Early spermatids: 241.6;Late spermatids: 606.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "cerebral cortex: 31.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059583: " "unprognostic (3.89e-2)" "unprognostic (1.70e-1)" "prognostic favorable (4.70e-5)" "unprognostic (6.50e-2)" "unprognostic (4.74e-2)" "unprognostic (2.22e-2)" "unprognostic (4.17e-2)" "unprognostic (3.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-1)" "unprognostic (2.66e-2)" "unprognostic (7.87e-2)" DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 96.5;Microglial cells: 77.5;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cancer enhanced" "Detected in all" "Leukemia: 68.5" "Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 32.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 925.7;Inhibitory neurons: 562.4;Oligodendrocyte precursor cells: 243.6" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Group enriched" "Detected in many" 7 "basal ganglia: 32.3;cerebral cortex: 14.4;hippocampal formation: 9.2;hypothalamus: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "lung cancer: 1.9;Neuroblastoma: 4.1;Rhabdoid: 4.6" "Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 192.8" HPA020321 Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 146.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 112.4;Extravillous trophoblasts: 119.7;NK-cells: 120.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 27 "amygdala: 46.5;basal ganglia: 75.1;cerebral cortex: 146.2;hippocampal formation: 133.8;white matter: 51.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear speckles" "HPA051336: AB_2681448" "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3243.7;Inhibitory neurons: 2539.6;Oligodendrocyte precursor cells: 2233.0;Oligodendrocytes: 3977.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Bone cancer: 48.5" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" DNAJC30 WBSCR18 ENSG00000176410 "DnaJ heat shock protein family (Hsp40) member C30" Q96LL9 7 73680918-73683453 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" Chaperone "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 108.6;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA017318 Supported NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 6: Late spermatids - Spermatogenesis" "HPA017318: AB_1858788" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (2.66e-2)" "unprognostic (4.53e-1)" "unprognostic (3.93e-2)" "unprognostic (2.85e-3)" "unprognostic (4.60e-2)" "prognostic favorable (4.91e-8)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" DOCK10 "KIAA0694, ZIZ3" ENSG00000135905 "Dedicator of cytokinesis 10" Q96BY6 2 224765090-225042468 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.1;lymphoid tissue: 32.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1704.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058106 Enhanced Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA058106: AB_2683606" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-3)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (3.44e-2)" "unprognostic (3.80e-1)" "unprognostic (3.22e-3)" "unprognostic (3.39e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (2.54e-1)" "unprognostic (7.72e-2)" DOCK3 "KIAA0299, MOCA, PBP" ENSG00000088538 "Dedicator of cytokinesis 3" Q8IZD9 3 50674927-51384198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.5;thyroid gland: 12.2" "Group enriched" "Detected in some" 11 "Astrocytes: 216.7;Excitatory neurons: 766.0;Inhibitory neurons: 817.9;Oligodendrocyte precursor cells: 426.5;Oligodendrocytes: 769.1" "Group enriched" "Detected in many" 4 "glioma: 2.7;thyroid cancer: 7.6" "Group enriched" "Detected in many" 8 "amygdala: 9.9;basal ganglia: 12.8;cerebral cortex: 17.5;hippocampal formation: 13.4;white matter: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037543, HPA037544" Enhanced Supported Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 32: Neurons - Synaptic function" Cytosol "HPA037543: AB_10672495, HPA037544: AB_10670383" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-3)" "unprognostic (6.35e-8)" "unprognostic (2.63e-1)" "unprognostic (3.02e-2)" "unprognostic (4.64e-2)" "unprognostic (3.67e-1)" "unprognostic (1.91e-1)" "unprognostic (7.99e-2)" "unprognostic (2.36e-3)" "unprognostic (1.34e-2)" "unprognostic (1.45e-2)" "unprognostic (5.83e-5)" "unprognostic (7.96e-2)" "unprognostic (6.19e-2)" "unprognostic (1.24e-1)" DPF1 "BAF45b, NEUD4, neuro-d4" ENSG00000011332 "Double PHD fingers 1" Q92782 19 38211006-38229714 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 23.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.2;Early spermatids: 16.0;Excitatory neurons: 24.2;Horizontal cells: 27.6;Inhibitory neurons: 15.9;Late spermatids: 28.1;Oligodendrocyte precursor cells: 12.0" "Group enriched" "Detected in some" 5 "glioma: 5.6;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049148 Enhanced Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" Mitochondria "HPA049148: AB_2680653" "unprognostic (7.72e-2)" "unprognostic (2.33e-1)" "unprognostic (5.38e-2)" "unprognostic (4.11e-3)" "unprognostic (8.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-4)" "unprognostic (1.40e-2)" "unprognostic (2.72e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-3)" "unprognostic (2.87e-2)" "unprognostic (1.11e-16)" "unprognostic (2.56e-1)" "unprognostic (3.75e-1)" "unprognostic (6.96e-2)" "unprognostic (8.20e-4)" DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153887097-154894285 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.0;endometrium 1: 58.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 664.4;Inhibitory neurons: 1169.8;Oligodendrocyte precursor cells: 1865.2" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 11.5" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" "HPA050509: AB_2681150" "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 21.3;retina: 8.4" "Group enriched" "Detected in some" 15 "Bipolar cells: 31.8;Horizontal cells: 42.9" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.3;Bone cancer: 1.9" "Region enriched" "Detected in many" 9 "basal ganglia: 164.4" "Region enriched" "Detected in many" 13 "basal ganglia: 86.7" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 9: Neurons - Nervous system development" "Plasma membrane" Cytosol "HPA013393: AB_1847833, HPA017304: " "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409605-113475691 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 77.8;pituitary gland: 59.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.4;Horizontal cells: 16.0" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 77.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.0" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "basal ganglia: 205.3" "Region enriched" "Detected in many" 4 "basal ganglia: 146.3" "HPA015139, HPA015691" Supported Supported NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Neurons - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "HPA015139: , HPA015691: AB_1847834" "unprognostic (8.49e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-4)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.40e-2)" "unprognostic (8.33e-4)" "unprognostic (1.10e-1)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (4.82e-2)" "unprognostic (8.49e-3)" DYNC1I1 "DNCI1, DNCIC1" ENSG00000158560 "Dynein cytoplasmic 1 intermediate chain 1" O14576 7 95772506-96110322 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 451.0;Inhibitory neurons: 365.3;Oligodendrocyte precursor cells: 87.1;Oligodendrocytes: 201.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061689 Enhanced Supported NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA061689: AB_2684586" "unprognostic (2.61e-1)" "unprognostic (4.58e-2)" "unprognostic (3.83e-2)" "prognostic favorable (3.79e-4)" "unprognostic (6.27e-2)" "unprognostic (2.11e-4)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (2.18e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (5.86e-2)" "unprognostic (2.24e-4)" "unprognostic (2.25e-4)" "unprognostic (1.63e-1)" "unprognostic (7.81e-4)" "unprognostic (1.10e-2)" ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 106.9;ovary: 99.7;pituitary gland: 27.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.6;Muller glia cells: 93.5;Peritubular cells: 20.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enhanced" "Detected in many" "hypothalamus: 106.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.1;lung cancer: 6.7" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 827.1;Proximal tubular cells: 780.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6;fallopian tube: 19.7" "Cell type enhanced" "Detected in some" "Early spermatids: 13.7;Endometrial ciliated cells: 33.2;Late spermatids: 29.1;Respiratory ciliated cells: 24.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: AB_10672605, HPA057532: " "unprognostic (2.06e-3)" "unprognostic (1.87e-2)" "unprognostic (2.96e-2)" "unprognostic (4.34e-3)" "unprognostic (1.81e-1)" "unprognostic (7.59e-4)" "unprognostic (2.37e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (1.20e-1)" "unprognostic (5.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (4.59e-2)" EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.1;fallopian tube: 14.7" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Early spermatids: 86.7;Endometrial ciliated cells: 58.9;Late spermatids: 23.7;Respiratory ciliated cells: 55.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 16.4;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.4;NK-cells: 5.8" "Cancer enhanced" "Detected in some" "Leukemia: 1.5" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "HPA034492: AB_10671227" "unprognostic (1.93e-1)" "unprognostic (7.80e-3)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (6.83e-3)" "unprognostic (5.07e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (7.89e-2)" "unprognostic (1.06e-1)" "unprognostic (6.13e-4)" "unprognostic (1.64e-3)" "unprognostic (4.97e-2)" EIF1AX "eIF-1A, eIF-4C, EIF1A, EIF4C" ENSG00000173674 "Eukaryotic translation initiation factor 1A X-linked" P47813 X 20124525-20141838 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 48: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" Cytosol "HPA002561: AB_1078724" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (9.69e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-3)" "unprognostic (7.13e-3)" "unprognostic (2.22e-1)" "unprognostic (8.28e-2)" "unprognostic (1.02e-3)" "unprognostic (2.82e-2)" "unprognostic (4.73e-2)" "unprognostic (8.66e-2)" "unprognostic (2.23e-3)" "unprognostic (7.81e-2)" "unprognostic (1.61e-1)" "unprognostic (1.52e-1)" EIF1AY ENSG00000198692 "Eukaryotic translation initiation factor 1A Y-linked" O14602 Y 20575776-20593154 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 121.3;tongue: 131.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 447.5;Erythroid cells: 266.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "cerebral cortex: 34.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Cytosol "HPA002561: AB_1078724" "unprognostic (4.31e-2)" "unprognostic (3.74e-1)" "unprognostic (2.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (2.89e-2)" "unprognostic (4.18e-2)" "unprognostic (2.17e-2)" "unprognostic (4.10e-2)" "unprognostic (8.53e-3)" "unprognostic (2.89e-1)" "unprognostic (6.03e-2)" ELAVL2 "HEL-N1, HuB" ENSG00000107105 "ELAV like RNA binding protein 2" Q12926 9 23690104-23826337 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 31.8;testis: 43.1" "Cell type enhanced" "Detected in some" "Early spermatids: 66.6;Excitatory neurons: 133.8;Inhibitory neurons: 381.8;Spermatogonia: 181.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 22.2" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022222, HPA063001" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm Cytosol "CAB022222: , HPA063001: AB_2684918" "unprognostic (3.51e-1)" "unprognostic (4.18e-2)" "unprognostic (2.05e-1)" "unprognostic (1.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-1)" "unprognostic (4.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.23e-1)" "unprognostic (1.01e-1)" "unprognostic (9.74e-4)" "unprognostic (3.98e-1)" "unprognostic (9.08e-4)" "unprognostic (8.30e-2)" "unprognostic (1.91e-2)" "unprognostic (2.12e-1)" "unprognostic (2.65e-1)" EMX2 ENSG00000170370 "Empty spiracles homeobox 2" Q04743 10 117542445-117549546 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 79.0;epididymis: 104.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 286.3;Collecting duct cells: 212.7;Distal tubular cells: 139.9;Endometrial stromal cells: 117.1;Granulosa cells: 104.8;Melanocytes: 113.2;Proximal tubular cells: 204.1" "Group enriched" "Detected in many" 13 "endometrial cancer: 40.8;ovarian cancer: 52.8;renal cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 4.4;ovarian cancer: 13.5;Uterine cancer: 12.2" "Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 13.3;basal ganglia: 14.2;cerebral cortex: 17.8;hippocampal formation: 22.8;white matter: 8.1" "HPA003497, HPA065294" Enhanced Supported Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA003497: , HPA065294: AB_2685455" "unprognostic (1.53e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.21e-3)" "unprognostic (5.41e-3)" "unprognostic (1.69e-1)" "unprognostic (3.53e-2)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (7.33e-2)" "unprognostic (1.76e-1)" "unprognostic (2.77e-1)" "prognostic favorable (2.28e-13)" "unprognostic (3.65e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 1695.6" "Group enriched" "Detected in many" 5 "Bipolar cells: 356.0;Cone photoreceptor cells: 1178.8;Horizontal cells: 298.7;Rod photoreceptor cells: 655.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.3;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.4;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Enhanced "Plasma membrane,Cytosol" NA NA 55000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 68: Kidney - Mixed function" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.7;Astrocytes: 65.2;Cardiomyocytes: 115.8;Enteroendocrine cells: 95.1;Excitatory neurons: 65.7;Oligodendrocyte precursor cells: 130.0;Serous glandular cells: 128.6" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 75.2" "Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 70 "Enteroendocrine cells: 541.3" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 37.2" "Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 55: Endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 30.9;Excitatory neurons: 36.2;Glandular and luminal cells: 27.5;Horizontal cells: 52.6;Inhibitory neurons: 53.5;Muller glia cells: 117.6" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8" "Adipose visceral - Mesothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 209.0;Early spermatids: 247.9;Syncytiotrophoblasts: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 18: Non-specific - Mixed function" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 133.2;Endometrial stromal cells: 56.9;Fibroblasts: 58.1;Late spermatids: 49.8;Leydig cells: 66.1;Peritubular cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 643.4;Peritubular cells: 484.9;Smooth muscle cells: 648.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 68: Kidney - Mixed function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 171.8;Endometrial stromal cells: 107.3;Granulosa cells: 103.0;Microglial cells: 114.0;Oligodendrocytes: 124.1;Skeletal myocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" FRMD4B "GRSP1, KIAA1013" ENSG00000114541 "FERM domain containing 4B" Q9Y2L6 3 69168782-69542583 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 311.3;Oligodendrocytes: 1141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009705 Uncertain Supported Approved "Nucleoplasm,Golgi apparatus,Centriolar satellite" NA NA 17000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Centriolar satellite" "Nucleoplasm, Golgi apparatus" "HPA009705: AB_1849147" "unprognostic (1.36e-1)" "unprognostic (2.92e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (4.59e-2)" "unprognostic (9.73e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (2.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-2)" "unprognostic (8.23e-2)" "prognostic favorable (5.01e-4)" "unprognostic (1.49e-1)" "unprognostic (7.54e-2)" "unprognostic (2.79e-1)" "unprognostic (4.39e-3)" FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 194.0;Late spermatids: 475.5;Squamous epithelial cells: 122.3;Suprabasal keratinocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 90.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 381.0;Inhibitory neurons: 385.2" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 32: Neurons - Synaptic function" "CAB079065: , HPA013820: AB_1849364, HPA031684: AB_2673993" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 55.1;retina: 17.8" "Group enriched" "Detected in some" 6 "Bipolar cells: 172.3;Excitatory neurons: 217.5;Inhibitory neurons: 210.3" "Cancer enriched" "Detected in single" 5 "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "breast cancer: 2.5" "Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 2: DU4475 - Unknown function" "Cluster 35: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: AB_2682904" "unprognostic (2.58e-2)" "unprognostic (4.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.31e-1)" "unprognostic (2.43e-1)" GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 4 "Astrocytes: 412.2;Excitatory neurons: 154.0;Inhibitory neurons: 108.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.4" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.5;choroid plexus: 16.3;retina: 9.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 69.3;Hofbauer cells: 13.9;Inhibitory neurons: 21.7;Oligodendrocyte precursor cells: 55.8" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 111.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 27.1;Inhibitory neurons: 13.8" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Group enriched" "Detected in many" 4 "amygdala: 52.0;basal ganglia: 73.5;cerebral cortex: 98.6;hippocampal formation: 111.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079022: , HPA029363: , HPA077031: AB_2686825" "unprognostic (6.33e-2)" "unprognostic (8.94e-3)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (9.50e-3)" "unprognostic (2.57e-1)" "unprognostic (7.63e-2)" "unprognostic (8.50e-2)" "unprognostic (1.44e-2)" GABRG2 ENSG00000113327 "Gamma-aminobutyric acid type A receptor subunit gamma2" P18507 5 162000057-162162977 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.0;retina: 10.9" "Group enriched" "Detected in some" 9 "Bipolar cells: 112.0;Excitatory neurons: 236.8;Horizontal cells: 69.2;Inhibitory neurons: 163.9" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Group enriched" "Detected in many" 5 "B-cells: 1.6;granulocytes: 4.5;T-cells: 1.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 34.7" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079060 Supported NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 52: Spermatids - Smell perception" "Cluster 38: Neurons - Neuronal signaling" "CAB079060: " "unprognostic (2.88e-2)" "unprognostic (1.56e-2)" "unprognostic (6.31e-3)" "unprognostic (3.07e-3)" "unprognostic (1.52e-1)" GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 15 "Horizontal cells: 130.1;Inhibitory neurons: 383.8;Oligodendrocyte precursor cells: 140.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 37: Neurons - Neuronal signaling" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 31.5;Ductal cells: 31.5;Endometrial ciliated cells: 67.1;Endometrial stromal cells: 53.0;Exocrine glandular cells: 26.7;Extravillous trophoblasts: 56.2;Glandular and luminal cells: 25.4;Pancreatic endocrine cells: 87.6" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 218.5" "Colon - Colon enteroendocrine cells, Skin - Sebaceous gland cells" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 74: Pancreatic cells - Mixed function" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "brain: 277.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 266.7" "Cancer enriched" "Detected in many" 43 "glioma: 245.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 94.3" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "CAB004417: AB_627660, CAB078783: AB_2620096, HPA013392: AB_1849468, HPA015600: AB_1849466" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-2)" "unprognostic (5.72e-5)" "unprognostic (7.44e-3)" "unprognostic (2.19e-2)" "unprognostic (3.97e-3)" "unprognostic (3.15e-3)" "unprognostic (6.08e-4)" "unprognostic (3.33e-1)" "unprognostic (2.17e-2)" "unprognostic (1.62e-1)" "unprognostic (5.35e-8)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.29e-3)" GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 13076.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 370.1" "Cancer enriched" "Detected in some" 368 "glioma: 2468.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.2;NK-cells: 1.7" "Cancer enriched" "Detected in all" 51 "Brain cancer: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 170000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Intermediate filaments" "CAB000039: AB_10013382, HPA056030: AB_2683015, HPA063513: AB_2685027" "unprognostic (1.79e-2)" "unprognostic (2.74e-1)" "unprognostic (9.83e-2)" "unprognostic (2.12e-5)" "unprognostic (4.08e-1)" "unprognostic (5.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (6.57e-3)" "unprognostic (7.35e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.75e-5)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 325.5;Astrocytes: 267.6;Cardiomyocytes: 222.8;Endometrial stromal cells: 211.0;Granulosa cells: 487.8;Suprabasal keratinocytes: 262.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 371.0;testis cancer: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" GKAP1 "FKSG21, GKAP42" ENSG00000165113 "G kinase anchoring protein 1" Q5VSY0 9 83739425-83829516 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 50.1;testis: 199.5" "Group enriched" "Detected in all" 10 "Early spermatids: 1387.7;Late spermatids: 583.9;Spermatocytes: 543.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035117, HPA035118, HPA066173" Enhanced Supported Approved "Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 55: Non-specific - Unknown function" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Centriolar satellite, Cytosol" "HPA035117: AB_2674473, HPA035118: AB_10671100, HPA066173: AB_2732740" "unprognostic (1.91e-1)" "unprognostic (2.94e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (9.62e-2)" "unprognostic (2.50e-1)" "unprognostic (2.52e-3)" "unprognostic (7.66e-3)" "unprognostic (3.04e-1)" "unprognostic (1.86e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.18e-1)" "prognostic favorable (1.05e-6)" "unprognostic (9.73e-2)" "unprognostic (1.38e-2)" "unprognostic (2.06e-1)" "unprognostic (6.24e-3)" GLRA1 STHE ENSG00000145888 "Glycine receptor alpha 1" P23415 5 151822513-151924851 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 40.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Excitatory neurons: 1.7;Inhibitory neurons: 4.9;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Group enriched" "Detected in many" 5 "hypothalamus: 9.4;midbrain: 15.1;pons and medulla: 26.3" "Low region specificity" "Detected in many" "HPA078885, CAB079042" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 47: Retina - Visual perception" "Cluster 37: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "CAB079042: , HPA078885: " "unprognostic (3.17e-1)" "unprognostic (2.47e-1)" "unprognostic (3.85e-7)" "unprognostic (8.24e-2)" "unprognostic (9.45e-3)" GMFB GMF ENSG00000197045 "Glia maturation factor beta" P60983 14 54474484-54489026 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 90.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Approved Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 46: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (7.93e-2)" "unprognostic (7.69e-3)" "unprognostic (4.81e-3)" "unprognostic (2.99e-2)" "unprognostic (1.12e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.48e-2)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "prognostic favorable (9.48e-5)" "unprognostic (1.80e-1)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (9.09e-2)" GMFG ENSG00000130755 "Glia maturation factor gamma" O60234 19 39328353-39342372 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 577.4;lymphoid tissue: 460.7" "Cell type enhanced" "Detected in many" "Adipocytes: 289.5;Hofbauer cells: 689.9;Kupffer cells: 506.4;Langerhans cells: 412.3;Macrophages: 369.5;monocytes: 654.3;NK-cells: 345.2;T-cells: 364.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 23 "Leukemia: 584.8;lymphoma: 191.5;Myeloma: 263.4" "Breast - Endothelial cells, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Uncertain Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 17: RS4;11 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (1.22e-2)" "prognostic favorable (7.35e-4)" "unprognostic (2.37e-2)" "unprognostic (1.21e-3)" "unprognostic (9.93e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.84e-2)" "unprognostic (1.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.11e-6)" "unprognostic (3.01e-1)" "unprognostic (8.76e-3)" "unprognostic (1.06e-1)" "unprognostic (5.27e-3)" GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 208.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "Early spermatids: 474.4;Late spermatids: 1169.8;monocytes: 185.0;NK-cells: 348.0" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 77.1;skin cancer: 58.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 33: Skin cancer - Membrane components" "Cluster 36: Spermatids - Spermatogenesis" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 360.9" "Cell type enhanced" "Detected in many" "B-cells: 120.9;dendritic cells: 129.9;Horizontal cells: 92.9;Muller glia cells: 87.2;Oligodendrocyte precursor cells: 98.2;Oligodendrocytes: 194.6;Plasma cells: 132.7" "Cancer enhanced" "Detected in all" "glioma: 21.9;melanoma: 20.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.2;naive B-cell: 50.1;plasmacytoid DC: 48.0" "Group enriched" "Detected in many" 4 "B-cells: 57.2;dendritic cells: 48.0" "Group enriched" "Detected in many" 6 "Leukemia: 14.7;lymphoma: 17.3;Myeloma: 27.2;skin cancer: 8.7" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "basal ganglia: 1277.2" HPA057790 Supported Supported NA NA 72000 "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "HPA057790: AB_2683527" "unprognostic (3.97e-3)" "unprognostic (1.16e-4)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-1)" "unprognostic (8.42e-4)" "prognostic favorable (3.05e-4)" "prognostic favorable (1.35e-5)" "unprognostic (1.27e-2)" "unprognostic (4.95e-2)" "prognostic favorable (3.71e-4)" "unprognostic (1.27e-1)" "prognostic favorable (0.00e+0)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (4.96e-2)" GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 46: Non-specific - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" GPR151 "GALR4, PGR7" ENSG00000173250 "G protein-coupled receptor 151" Q8TDV0 5 146513103-146516190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 8.8" "Cell type enriched" "Detected in single" 4 "Cone photoreceptor cells: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "midbrain: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 19 "thalamus: 30.6" "Region enriched" "Detected in single" 9 "thalamus: 4.7" HPA065728 Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: Photoreceptor cells - Visual perception" "HPA065728: " "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-2)" GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 10 "Oligodendrocyte precursor cells: 55.8" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" GPR88 ENSG00000181656 "G protein-coupled receptor 88" Q9GZN0 1 100538139-100542021 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 93.9" "Cell type enriched" "Detected in some" 8 "Horizontal cells: 15.4" "Cancer enriched" "Detected in some" 9 "liver cancer: 12.0" "Region enriched" "Detected in many" 7 "basal ganglia: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "basal ganglia: 718.8" "Region enriched" "Detected in many" 42 "basal ganglia: 273.1" HPA007488 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 9: Neurons - Nervous system development" "HPA007488: AB_2667844" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (8.37e-3)" "unprognostic (5.41e-1)" "unprognostic (5.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "unprognostic (7.76e-2)" "unprognostic (8.23e-3)" "unprognostic (2.45e-1)" "unprognostic (3.93e-4)" "unprognostic (1.85e-2)" "unprognostic (5.56e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-2)" GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 27.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 212.6;Inhibitory neurons: 135.2;Rod photoreceptor cells: 127.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 27.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 6.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Excitatory neurons: 16.0;Horizontal cells: 7.7;Rod photoreceptor cells: 3.6;Spermatocytes: 3.2" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" "HPA027868: , HPA065166: AB_2685425" "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 13.5;Granulosa cells: 40.8;Inhibitory neurons: 34.8;Smooth muscle cells: 71.0;Syncytiotrophoblasts: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 43.6;testis cancer: 70.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" HCRT "OX, PPOX" ENSG00000161610 "Hypocretin neuropeptide precursor" O43612 17 42184060-42185452 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1067 "brain: 384.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 2.0;Enteroendocrine cells: 1.9;Kupffer cells: 3.9;Oligodendrocyte precursor cells: 1.9;Pancreatic endocrine cells: 1.7" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 7 "hypothalamus: 384.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "hypothalamus: 93.5" "Region enriched" "Detected in some" 21 "hypothalamus: 25.3" "HPA064801, CAB079778" Enhanced Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 2: T-cells - T-cell receptor" "CAB079778: , HPA064801: " "unprognostic (3.34e-2)" "unprognostic (7.76e-5)" "unprognostic (3.21e-2)" "unprognostic (3.01e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 118.6;Excitatory neurons: 433.7;Inhibitory neurons: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 38: Neurons - Neuronal signaling" Cytosol "CAB004437: AB_627742, HPA036521: AB_2675170, HPA036522: AB_2675171" "unprognostic (2.80e-1)" "unprognostic (5.30e-2)" "unprognostic (4.00e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (6.40e-2)" "unprognostic (2.00e-3)" "unprognostic (2.41e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (3.07e-3)" "unprognostic (3.98e-1)" "unprognostic (7.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (2.83e-2)" "unprognostic (2.86e-3)" HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 180.9;Endometrial ciliated cells: 174.0;Glandular and luminal cells: 140.0;Mucus glandular cells: 134.3;Prostatic glandular cells: 227.6" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 14: Endometrium - Transcription regulation" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 77.2;Muller glia cells: 75.2;Proximal tubular cells: 80.5;Theca cells: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" HPF1 "C4orf27, FLJ20534" ENSG00000056050 "Histone PARylation factor 1" Q9NWY4 4 169729470-169757944 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043467 Uncertain Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 12: Non-specific - Chromatin organization" Cytosol "Microtubules, Cytokinetic bridge" "HPA043467: AB_10793949" "unprognostic (1.09e-1)" "unprognostic (1.15e-2)" "unprognostic (1.72e-2)" "unprognostic (1.47e-1)" "unprognostic (2.70e-1)" "unprognostic (1.09e-1)" "unprognostic (8.68e-3)" "unprognostic (2.74e-2)" "prognostic unfavorable (5.63e-4)" "prognostic favorable (7.47e-4)" "unprognostic (6.34e-2)" "unprognostic (4.55e-1)" "unprognostic (3.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.32e-1)" "unprognostic (5.51e-2)" "unprognostic (1.09e-1)" HSPA2 ENSG00000126803 "Heat shock protein family A (Hsp70) member 2" P54652 14 64535905-64546173 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 320.2;skeletal muscle: 170.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 260.7;Extravillous trophoblasts: 597.4;Spermatocytes: 535.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA000798, HPA052504" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA 63000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 31: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA000798: AB_1079090, HPA052504: AB_2681854" "prognostic favorable (1.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.73e-1)" "unprognostic (1.08e-2)" "unprognostic (3.78e-2)" "unprognostic (2.90e-2)" "unprognostic (7.11e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.31e-1)" "unprognostic (3.14e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-1)" "unprognostic (5.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.6;parathyroid gland: 13.1;testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Excitatory neurons: 5.8;Inhibitory neurons: 23.8;Spermatocytes: 11.0" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Cancer enhanced" "Detected in many" "Brain cancer: 8.2" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in some" "Astrocytes: 18.0;Cone photoreceptor cells: 12.1;Leydig cells: 34.1;Melanocytes: 17.4;Microglial cells: 13.7;Oligodendrocyte precursor cells: 16.8;Rod photoreceptor cells: 13.4;Skeletal myocytes: 21.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.4" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1239.4;Leydig cells: 1826.4;Muller glia cells: 615.9;Peritubular cells: 1001.5;Sertoli cells: 616.4;Smooth muscle cells: 1293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 341.6;breast cancer: 389.0" "Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040514, HPA070407" Supported Approved Vesicles "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA040514: AB_2677016, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" INA "NEF5, NF-66" ENSG00000148798 "Internexin neuronal intermediate filament protein alpha" Q16352 10 103277138-103290346 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 160.7;pituitary gland: 41.4;retina: 97.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 55.6;Cone photoreceptor cells: 77.5;Early spermatids: 39.6;Excitatory neurons: 28.3;Horizontal cells: 71.1;Inhibitory neurons: 38.9;Late spermatids: 30.6;Rod photoreceptor cells: 28.8" "Group enriched" "Detected in many" 4 "glioma: 4.7;testis cancer: 18.2;urothelial cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 57.3;Neuroblastoma: 60.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002059, HPA007572, HPA008057" Enhanced Supported Approved "Intermediate filaments,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Intermediate filaments" Cytosol "CAB002059: AB_442031, HPA007572: , HPA008057: AB_1851833" "unprognostic (1.77e-1)" "unprognostic (2.50e-2)" "unprognostic (9.54e-2)" "unprognostic (5.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.45e-3)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "unprognostic (8.09e-3)" "unprognostic (3.07e-2)" "unprognostic (1.78e-3)" "unprognostic (1.66e-1)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" IPO7 "Imp7, RANBP7" ENSG00000205339 "Importin 7" O95373 11 9384652-9448127 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019002, HPA056590" Approved Approved Supported Nucleoplasm,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Cytosol" "HPA019002: AB_1856059, HPA056590: AB_2683180" "unprognostic (1.92e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (9.50e-2)" "unprognostic (1.27e-1)" "unprognostic (3.68e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.19e-2)" "unprognostic (7.60e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (8.38e-6)" "unprognostic (3.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.08e-2)" "unprognostic (2.17e-1)" "unprognostic (3.90e-3)" IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 43: Non-specific - Mitochondria" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Nucleoplasm "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;intestine: 18.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 51.2;Early spermatids: 44.5;Excitatory neurons: 23.4;Gastric mucus-secreting cells: 30.4;Late spermatids: 168.3;Proximal enterocytes: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;retina: 18.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9688.5;Inhibitory neurons: 1921.9;Oligodendrocyte precursor cells: 4956.5" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Kidney - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 58: Brain - Synaptic function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.2;choroid plexus: 18.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 94.1;Inhibitory neurons: 44.1;Oligodendrocytes: 82.1;Schwann cells: 137.7" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 13.7" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA072287: AB_2686507" "unprognostic (3.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.69e-2)" "unprognostic (2.62e-2)" "unprognostic (6.98e-2)" "unprognostic (1.13e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-2)" "unprognostic (3.50e-1)" "unprognostic (2.95e-2)" "unprognostic (3.75e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-2)" KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 290.9;Endothelial cells: 267.3;Enteroendocrine cells: 389.2;Hofbauer cells: 227.7;Kupffer cells: 408.2;Macrophages: 308.1;monocytes: 197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cancer enhanced" "Detected in all" "Neuroblastoma: 39.4" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 69: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.3;pituitary gland: 4.1" "Group enriched" "Detected in some" 9 "Astrocytes: 115.8;Early spermatids: 49.2;Excitatory neurons: 127.3;Inhibitory neurons: 71.0;Late spermatids: 102.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Group enriched" "Detected in many" 4 "granulocytes: 528.4;Melanocytes: 391.9" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Cancer enhanced" "Detected in many" "Bone cancer: 19.6;Leukemia: 32.3" "Adipose subcutaneous - Mast cells, Lung - Mast cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 99.0;Endothelial cells: 72.8;Fibroblasts: 91.7;Hepatocytes: 138.9;Microglial cells: 125.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 65: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" LHX2 "hLhx2, LH-2" ENSG00000106689 "LIM homeobox 2" P50458 9 124001670-124033301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 99.8;choroid plexus: 48.5;retina: 34.1" "Cell type enhanced" "Detected in some" "Astrocytes: 66.4;Early spermatids: 25.8;Excitatory neurons: 20.4;Late spermatids: 36.7;Muller glia cells: 196.4" "Group enriched" "Detected in many" 5 "cervical cancer: 3.2;glioma: 10.7;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 20.2" "Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000838 Supported Approved Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 27: TE 441.T - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "HPA000838: AB_2666109" "unprognostic (3.60e-3)" "prognostic favorable (9.52e-4)" "unprognostic (3.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (6.37e-3)" "unprognostic (1.07e-1)" "unprognostic (4.59e-2)" "unprognostic (3.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.32e-2)" "unprognostic (4.66e-15)" "unprognostic (1.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.46e-2)" "unprognostic (1.77e-1)" LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 44.0" "Cell type enhanced" "Detected in many" "Club cells: 30.6;Excitatory neurons: 36.4;Inhibitory neurons: 37.9;Ionocytes: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 10: Brain - Neuronal signaling" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" LPCAT2 "AGPAT11, AYTL1, FLJ20481, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.3;thyroid gland: 86.3" "Cell type enhanced" "Detected in many" "granulocytes: 129.2;Microglial cells: 218.9;monocytes: 97.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 23.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.4;eosinophil: 199.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: Skin cancer - Membrane components" "Cluster 69: Macrophages - Innate immune response" "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favorable (3.43e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Cell type enriched" "Detected in some" 33 "Serous glandular cells: 941.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 604.2;Syncytiotrophoblasts: 761.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518, HPA073239" Enhanced Supported Enhanced "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 28: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292, HPA073239: " "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 30.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1809.9" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.4" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 431.3;retina: 154.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 440.2;Cone photoreceptor cells: 1113.3;Excitatory neurons: 563.9;Horizontal cells: 834.4;Sertoli cells: 508.6;Smooth muscle cells: 468.5" "Cancer enriched" "Detected in all" 5 "glioma: 48.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 114.7;testis cancer: 109.7" "Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Enhanced Cytosol NA NA 180000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "CAB009792: AB_2137420, HPA022275: AB_1853944" "unprognostic (9.96e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (3.70e-1)" "unprognostic (4.67e-3)" "unprognostic (2.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (7.00e-2)" "unprognostic (4.78e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (8.22e-5)" MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424058-209734118 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 253.3;retina: 411.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 875.5;Excitatory neurons: 870.6;Inhibitory neurons: 804.4;Oligodendrocyte precursor cells: 659.5;Rod photoreceptor cells: 524.7" "Group enriched" "Detected in many" 4 "glioma: 30.4;thyroid cancer: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001984, HPA008273, HPA012558, HPA012828" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "CAB001984: , HPA008273: AB_1853945, HPA012558: , HPA012828: AB_1853946" "unprognostic (2.47e-2)" "unprognostic (2.81e-1)" "unprognostic (2.58e-2)" "prognostic unfavorable (1.98e-6)" "unprognostic (2.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (6.06e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (7.28e-2)" "unprognostic (4.10e-5)" MAP6D1 "FLJ12748, SL21" ENSG00000180834 "MAP6 domain containing 1" Q9H9H5 3 183815922-183825594 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.6;choroid plexus: 24.9;skeletal muscle: 26.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocytes: 95.6" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037991 Enhanced Supported Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 65: Breast cancer - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA037991: AB_10672503" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-3)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-1)" "unprognostic (1.28e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (8.81e-12)" "unprognostic (1.08e-1)" "unprognostic (2.96e-3)" "unprognostic (1.86e-1)" "unprognostic (5.72e-2)" MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" MARS1 "CMT2U, MARS, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase 1" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol NA NA 23000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 18: Non-specific - Mixed function" Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavorable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2733.4" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "skin cancer: 213.8" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" MCC ENSG00000171444 "MCC regulator of WNT signaling pathway" P23508 5 113022099-113488823 "Predicted intracellular proteins" "Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 70.6" "Cell type enhanced" "Detected in many" "Astrocytes: 165.4;Bipolar cells: 119.4;Inhibitory neurons: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Sarcoma: 45.1" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037390, HPA037391" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: TE 441.T - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA037390: AB_2675451, HPA037391: AB_10671248" "unprognostic (6.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (8.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (5.21e-2)" "unprognostic (9.59e-2)" "unprognostic (8.02e-3)" "unprognostic (1.56e-1)" "unprognostic (1.74e-1)" "prognostic favorable (6.19e-4)" "unprognostic (1.70e-3)" "unprognostic (3.34e-1)" "unprognostic (2.47e-2)" "unprognostic (2.90e-1)" MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261940 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 58.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 203.2;monocytes: 241.5;Oligodendrocyte precursor cells: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 12: Non-specific - Chromatin organization" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 240.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 31: Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA031550: AB_10599733, HPA031551: AB_10601442, HPA031552: AB_10794616" "unprognostic (2.61e-1)" "unprognostic (9.86e-2)" "unprognostic (6.54e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.87e-2)" "unprognostic (3.97e-2)" "unprognostic (1.80e-2)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-2)" MX1 "IFI-78K, lncMX1-215, MxA" ENSG00000157601 "MX dynamin like GTPase 1" P20591 21 41420020-41470071 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 127.0" "Cell type enhanced" "Detected in many" "Adipocytes: 108.8;dendritic cells: 124.3;Extravillous trophoblasts: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030917, HPA030918, HPA049724" Approved Approved Supported "Nuclear membrane,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nuclear membrane, Cytosol" "HPA030917: AB_10602010, HPA030918: , HPA049724: AB_2680862" "unprognostic (3.62e-1)" "unprognostic (6.84e-2)" "unprognostic (3.41e-2)" "unprognostic (2.55e-2)" "unprognostic (3.97e-1)" "unprognostic (2.27e-1)" "unprognostic (1.35e-3)" "unprognostic (5.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (6.88e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (9.95e-2)" "unprognostic (8.10e-2)" "unprognostic (3.24e-1)" "unprognostic (1.81e-1)" MYG1 "C12orf10, Gamm1, MYG" ENSG00000139637 "MYG1 exonuclease" Q9HB07 12 53299695-53307177 "Disease related genes, Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.3;Inhibitory neurons: 8.4;Oligodendrocytes: 7.0;Pancreatic endocrine cells: 8.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038626, HPA038627" Approved Supported Supported Nucleoplasm "Intracellular and membrane" NA NA 20000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" Nucleoplasm "HPA038626: AB_10674692, HPA038627: AB_2676123" "unprognostic (5.33e-2)" "unprognostic (4.41e-2)" "unprognostic (6.77e-2)" "unprognostic (2.44e-2)" "unprognostic (3.59e-1)" "unprognostic (7.56e-2)" "unprognostic (1.61e-3)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (2.81e-1)" "unprognostic (6.41e-2)" "unprognostic (2.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 13 "Astrocytes: 690.8;Excitatory neurons: 853.9;Inhibitory neurons: 884.7;Oligodendrocyte precursor cells: 1655.8;Oligodendrocytes: 1441.1" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 34.5;Rhabdoid: 16.0" "Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" NCDN "NCDN-1, NCDN-2" ENSG00000020129 Neurochondrin Q9UBB6 1 35557473-35567274 "Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 424.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.2;Inhibitory neurons: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023676 Enhanced Supported Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: Non-specific - mRNA processing" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA023676: AB_1854325" "unprognostic (1.15e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (4.66e-2)" "unprognostic (1.41e-1)" "unprognostic (4.36e-2)" "prognostic favorable (3.73e-4)" "unprognostic (5.91e-3)" "unprognostic (5.34e-3)" "unprognostic (5.88e-3)" "unprognostic (2.87e-1)" "unprognostic (3.24e-2)" "unprognostic (2.23e-2)" NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 67.3;Inhibitory neurons: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 55: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" NECAB1 EFCBP1 ENSG00000123119 "N-terminal EF-hand calcium binding protein 1" Q8N987 8 90791741-90959393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 59.4;choroid plexus: 24.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 369.9;Oligodendrocytes: 290.6" "Cancer enhanced" "Detected in many" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210" Enhanced Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm Cytosol "CAB068208: AB_2665671, CAB068209: AB_2665672, CAB068210: AB_2665673, HPA023252: AB_1848013, HPA023629: AB_1848014, HPA025963: AB_1848015, HPA031262: AB_2673815" "unprognostic (8.09e-3)" "unprognostic (3.78e-1)" "unprognostic (8.17e-3)" "unprognostic (5.96e-5)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-3)" "unprognostic (8.38e-2)" "unprognostic (1.78e-3)" "unprognostic (2.60e-1)" "unprognostic (2.25e-2)" "unprognostic (2.57e-2)" "unprognostic (2.19e-3)" "unprognostic (4.45e-3)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (5.39e-3)" NECAB2 EFCBP2 ENSG00000103154 "N-terminal EF-hand calcium binding protein 2" Q7Z6G3 16 83968244-84002776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 106.4" "Cell type enhanced" "Detected in some" "Early spermatids: 16.7;Hepatocytes: 8.4;Inhibitory neurons: 21.6;Late spermatids: 47.7;Muller glia cells: 14.5;Proximal tubular cells: 20.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 66 "neutrophil: 55.4" "Lineage enriched" "Detected in single" 66 "granulocytes: 55.4" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "HPA013998, HPA014144, CAB068211" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 65: Brain - Ion transport" "Cluster 61: Liver - Metabolism" "Cluster 32: Neurons - Synaptic function" "CAB068211: AB_2665678, HPA013998: AB_1848016, HPA014144: AB_1848017" "unprognostic (5.27e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (3.48e-5)" "unprognostic (3.45e-2)" "unprognostic (4.20e-2)" "unprognostic (6.74e-2)" "unprognostic (8.79e-2)" "unprognostic (4.15e-1)" "unprognostic (2.59e-1)" "unprognostic (5.75e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (8.89e-3)" "unprognostic (3.48e-1)" "unprognostic (8.61e-3)" "unprognostic (3.75e-2)" NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 675.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Distal tubular cells: 52.9;Excitatory neurons: 63.8;Horizontal cells: 215.3;Rod photoreceptor cells: 39.7" "Cancer enhanced" "Detected in many" "renal cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 71.3" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 200000 "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: AB_1854397, HPA015021: AB_2669135" "unprognostic (7.63e-2)" "unprognostic (1.36e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" "unprognostic (2.82e-2)" "unprognostic (6.69e-2)" "unprognostic (3.69e-2)" "unprognostic (3.78e-3)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.91e-4)" "unprognostic (5.76e-3)" "unprognostic (7.88e-2)" "unprognostic (3.97e-3)" "unprognostic (3.17e-3)" NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;skin 1: 7.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.1;Gastric mucus-secreting cells: 25.6;Inhibitory neurons: 27.6" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" NPAS2 "bHLHe9, MOP4, PASD4" ENSG00000170485 "Neuronal PAS domain protein 2" Q99743 2 100820139-100996829 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.1;Early spermatids: 74.6;Excitatory neurons: 148.4;Inhibitory neurons: 57.0;Microglial cells: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019674 Uncertain Supported Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA019674: AB_10601275" "unprognostic (2.74e-1)" "unprognostic (8.89e-2)" "unprognostic (4.66e-2)" "unprognostic (5.06e-3)" "unprognostic (4.39e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (5.47e-3)" "unprognostic (4.48e-1)" "unprognostic (1.56e-1)" "unprognostic (1.59e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (3.55e-7)" "unprognostic (7.03e-2)" "unprognostic (6.58e-2)" "unprognostic (7.71e-3)" "unprognostic (1.34e-3)" NPTX1 ENSG00000171246 "Neuronal pentraxin 1" Q15818 17 80466834-80477843 "Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 107.8;intestine: 31.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 239.5;Excitatory neurons: 87.2;Horizontal cells: 34.6;Late spermatids: 44.5" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.4" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 55.3;cerebellum: 128.1;cerebral cortex: 102.2;hippocampal formation: 131.3" HPA077062 Enhanced Approved "Secreted in brain" NA NA 1100000 "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA077062: AB_2732329" "unprognostic (2.37e-2)" "unprognostic (1.18e-1)" "unprognostic (1.81e-2)" "unprognostic (6.95e-2)" "unprognostic (4.16e-3)" "unprognostic (2.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.63e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "unprognostic (9.63e-3)" "unprognostic (1.05e-6)" "unprognostic (1.41e-4)" "unprognostic (1.35e-1)" "unprognostic (8.86e-6)" "unprognostic (2.71e-3)" NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adrenal gland: 122.6;brain: 423.9;prostate: 332.8" "Cell type enriched" "Detected in some" 29 "Prostatic glandular cells: 1659.0" "Cancer enriched" "Detected in many" 187 "prostate cancer: 1214.9" "Region enriched" "Detected in all" 7 "hypothalamus: 423.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 15 "Neuroblastoma: 352.9;prostate cancer: 320.7" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Supported "Golgi apparatus" "Secreted to blood" NA NA 30700000 21000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 73: Prostatic glandular cells - Transcription" "Golgi apparatus" "CAB016733: , CAB034368: AB_2298657, HPA036636: , HPA044572: AB_2678996, HPA056798: AB_2630371" "unprognostic (2.00e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (4.15e-1)" "unprognostic (3.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "unprognostic (6.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 758.3;salivary gland: 771.4" "Cell type enhanced" "Detected in all" "Late spermatids: 627.1;Serous glandular cells: 1028.6;Syncytiotrophoblasts: 1621.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pancreas - Exocrine glandular cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1250000 690000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" OGFOD1 "FLJ10826, KIAA1612, TPA1" ENSG00000087263 "2-oxoglutarate and iron dependent oxygenase domain containing 1" Q8N543 16 56451521-56479104 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003215, HPA003722" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 36: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Nucleoplasm Cytosol "HPA003215: AB_1078881, HPA003722: " "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (3.80e-3)" "unprognostic (2.86e-2)" "unprognostic (2.48e-3)" "prognostic unfavorable (6.65e-4)" "prognostic unfavorable (7.02e-4)" "unprognostic (5.51e-2)" "unprognostic (6.87e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-2)" "unprognostic (4.59e-2)" "unprognostic (7.49e-2)" "unprognostic (7.20e-2)" "unprognostic (6.11e-2)" "unprognostic (1.25e-1)" "unprognostic (1.84e-2)" OPRM1 MOR1 ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 10.6;testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 34.1;Excitatory neurons: 40.6;Inhibitory neurons: 22.9;Late spermatids: 35.3;Microglial cells: 10.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "HPA014509: AB_1854801, HPA067435: " "unprognostic (7.34e-2)" "unprognostic (6.91e-2)" OSBPL9 ENSG00000117859 "Oxysterol binding protein like 9" Q96SU4 1 51577179-51798427 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 204.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027378, HPA027397" Supported Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: Non-specific - mRNA processing" "Cluster 35: Bipolar cells - Visual perception" "Golgi apparatus" Vesicles "HPA027378: AB_1854816, HPA027397: AB_1854817" "unprognostic (5.99e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-2)" "unprognostic (2.43e-3)" "unprognostic (3.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-1)" "unprognostic (4.17e-3)" "unprognostic (1.58e-1)" "unprognostic (8.36e-3)" "unprognostic (8.61e-2)" "unprognostic (3.64e-2)" "unprognostic (7.53e-3)" "unprognostic (2.55e-1)" "unprognostic (4.95e-2)" "unprognostic (3.37e-1)" OTP ENSG00000171540 "Orthopedia homeobox" Q5XKR4 5 77628712-77638713 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 134 "brain: 28.7" "Cell type enhanced" "Detected in some" "Spermatocytes: 2.5;Spermatogonia: 1.3" "Cancer enriched" "Detected in single" 6 "glioma: 1.2" "Region enhanced" "Detected in many" "hypothalamus: 28.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "lymphoma: 16.5;Rhabdoid: 5.9" "Region enriched" "Detected in many" 7 "hypothalamus: 20.0" "Region enhanced" "Detected in some" "hypothalamus: 15.5" HPA059342 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA059342: AB_2732635" "unprognostic (1.00e-1)" "unprognostic (2.40e-2)" "unprognostic (6.25e-2)" "unprognostic (8.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (7.77e-2)" "unprognostic (2.39e-2)" "unprognostic (9.66e-2)" "unprognostic (4.64e-2)" "unprognostic (7.76e-14)" "unprognostic (3.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.49e-3)" OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836, CAB080075" Approved Supported Approved "Cytosol,Cytoplasmic bodies" NA NA 500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" Cytosol "Cytoplasmic bodies" "CAB072836: , CAB080075: , HPA039176: AB_10674980" "unprognostic (2.50e-1)" "unprognostic (5.70e-3)" "unprognostic (3.93e-2)" "unprognostic (1.63e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.45e-1)" "unprognostic (1.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (6.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.84e-2)" "unprognostic (1.82e-1)" OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU deubiquitinase 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavorable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "brain: 1167.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 42.8;Late spermatids: 77.6;Proximal enterocytes: 18.2;Proximal tubular cells: 41.9" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.1" "Region enriched" "Detected in many" 141 "hypothalamus: 1167.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gastric cancer: 1.2" "Kidney - Proximal tubular cells" "Region enriched" "Detected in many" 6 "hypothalamus: 179.3" "Group enriched" "Detected in some" 903 "basal ganglia: 794.6;hypothalamus: 1854.1" HPA071892 Supported Supported "Secreted to blood" NA NA 1500000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: Liver cancer - Metabolism" "Cluster 36: Spermatids - Spermatogenesis" "HPA071892: AB_2732190" "unprognostic (7.45e-3)" "unprognostic (1.99e-2)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (8.22e-2)" "unprognostic (8.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.05e-2)" "unprognostic (6.65e-2)" "unprognostic (6.18e-1)" "unprognostic (3.81e-1)" "unprognostic (3.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 69.8;Cardiomyocytes: 82.5;Skeletal myocytes: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 216.3;Langerhans cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "classical monocyte: 182.2;eosinophil: 292.7;intermediate monocyte: 177.7;myeloid DC: 264.3;neutrophil: 431.8;non-classical monocyte: 202.6" "Group enriched" "Detected in all" 11 "dendritic cells: 264.3;granulocytes: 431.8;monocytes: 202.6" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 560000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" PARP1 "ADPRT, ARTD1, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360210-226408154 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 351.6;Cytotrophoblasts: 501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm NA NA 150000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: AB_2665732, CAB075727: AB_2665733, HPA045168: AB_2679240" "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 9 "B-cells: 112.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 11 "Leukemia: 32.8;lymphoma: 76.6" "Lung - B-cells, Skin - Outer root sheath cells" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm "CAB026269: , CAB026869: , HPA056394: AB_2683116" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 61.6;retina: 68.9" "Group enriched" "Detected in some" 6 "Horizontal cells: 481.9;Muller glia cells: 415.5" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "CAB034143: AB_1127044, HPA030775: AB_10601243" "unprognostic (2.89e-1)" "unprognostic (2.98e-2)" "unprognostic (8.34e-2)" "unprognostic (3.85e-2)" "unprognostic (4.42e-2)" "unprognostic (7.82e-2)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.24e-3)" "unprognostic (1.68e-1)" "unprognostic (1.20e-2)" "unprognostic (3.91e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (3.42e-3)" PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 4 "Early spermatids: 438.9;Spermatocytes: 361.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 19.0;brain: 21.2;retina: 61.7" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2839.5" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 6.1" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074437 Supported "Intracellular and membrane" NA NA 22000 "Cluster 77: Retina - Visual perception" "Cluster 26: NCI-H716 - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 645.6;Horizontal cells: 176.2;Inhibitory neurons: 729.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Nuclear speckles" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 647.3;seminal vesicle: 1280.1" "Group enriched" "Detected in many" 6 "Bipolar cells: 555.8;Cone photoreceptor cells: 417.0;Distal tubular cells: 513.1;Horizontal cells: 728.7;Proximal tubular cells: 1228.2" "Cancer enhanced" "Detected in many" "prostate cancer: 41.7;thyroid cancer: 48.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 28.4;Myeloma: 68.3" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: AB_1855086" "unprognostic (6.82e-2)" "prognostic favorable (9.76e-4)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.63e-1)" "prognostic favorable (1.85e-7)" "unprognostic (9.00e-2)" "unprognostic (2.99e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.5;Inhibitory neurons: 33.2;Squamous epithelial cells: 27.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Sebaceous gland cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 35: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 4508.3;Proximal tubular cells: 1361.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 47.0" "Group enriched" "Detected in some" 47 "Early spermatids: 39.8;Late spermatids: 122.5" "Group enriched" "Detected in some" 29 "glioma: 2.6;ovarian cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "Bone cancer: 4.2" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 132.2" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 6: Late spermatids - Spermatogenesis" "CAB079777: , HPA053342: AB_2682121" "unprognostic (7.00e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-2)" PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "Kupffer cells: 243.8;Squamous epithelial cells: 580.7;Suprabasal keratinocytes: 340.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Heart muscle - Macrophages, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" PMCH MCH ENSG00000183395 "Pro-melanin concentrating hormone" P20382 12 102196459-102197833 "Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hormone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "brain: 92.8" "Cell type enhanced" "Detected in single" "T-cells: 2.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 92.8;thalamus: 60.2" "Immune cell enriched" "Detected in some" 10 "T-reg: 9.5" "Lineage enriched" "Detected in single" 85 "T-cells: 9.5" "Cancer enhanced" "Detected in single" "lymphoma: 2.0" "Group enriched" "Detected in many" 129 "hypothalamus: 624.3;thalamus: 339.8" "Region enriched" "Detected in some" 34 "hypothalamus: 83.0" "HPA046055, HPA061884" Enhanced Supported "Secreted to blood" NA NA 274000 "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA046055: AB_2679517, HPA061884: AB_2684632" "unprognostic (3.23e-3)" "unprognostic (8.04e-2)" "unprognostic (3.96e-4)" "unprognostic (2.09e-2)" "unprognostic (1.75e-1)" "unprognostic (7.73e-2)" "unprognostic (4.31e-3)" "unprognostic (1.43e-2)" "unprognostic (3.18e-3)" "unprognostic (4.51e-2)" "unprognostic (1.21e-1)" "unprognostic (2.16e-6)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "unprognostic (5.10e-2)" "unprognostic (3.53e-2)" POU3F2 "BRN2, OCT7, OTF7, POUF3" ENSG00000184486 "POU class 3 homeobox 2" P20265 6 98834574-98839458 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 17.3" "Cell type enhanced" "Detected in some" "Astrocytes: 75.0;Excitatory neurons: 8.7;Muller glia cells: 9.9;Oligodendrocyte precursor cells: 26.0;Oligodendrocytes: 12.6" "Cancer enriched" "Detected in some" 11 "glioma: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 30.5;skin cancer: 11.1" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA047081, HPA056261" Approved Supported Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 14: Bone cancer - Transcription" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA047081: , HPA056261: AB_2683081" "unprognostic (5.94e-4)" "unprognostic (7.80e-2)" "unprognostic (3.07e-3)" "unprognostic (1.83e-1)" "unprognostic (3.57e-1)" "unprognostic (1.38e-1)" "unprognostic (1.17e-3)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (4.77e-1)" "unprognostic (9.38e-11)" "unprognostic (4.77e-2)" "unprognostic (2.84e-2)" "unprognostic (8.47e-3)" "unprognostic (4.04e-1)" POU4F1 "BRN3A, RDC-1" ENSG00000152192 "POU class 4 homeobox 1" Q01851 13 78598362-78603552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.3;retina: 2.6" "Cell type enhanced" "Detected in some" "dendritic cells: 4.5;Horizontal cells: 12.8;Skeletal myocytes: 3.0;Spermatocytes: 2.3;Spermatogonia: 2.8" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 4 "medulla oblongata: 9.3;midbrain: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 9.0" "Testis - Spermatocytes" "Group enriched" "Detected in some" 23 "midbrain: 2.5;pons and medulla: 2.1;thalamus: 2.2" "Region enhanced" "Detected in some" "medulla oblongata: 4.1" HPA068024 Enhanced Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 56: Neurons - Neuronal signaling" "Cluster 11: Non-specific - Transcription" "HPA068024: AB_2685943" "unprognostic (6.70e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (6.30e-2)" "unprognostic (6.00e-2)" "unprognostic (1.70e-2)" "unprognostic (9.17e-2)" "unprognostic (8.98e-2)" "unprognostic (9.95e-2)" "unprognostic (1.53e-1)" "unprognostic (4.75e-3)" PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 711.8;choroid plexus: 506.6;intestine: 211.4;salivary gland: 366.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 206.0;Distal enterocytes: 211.4;Distal tubular cells: 208.4;Enteroendocrine cells: 200.6;Intestinal goblet cells: 245.2;Melanocytes: 196.8;Paneth cells: 152.3;Serous glandular cells: 187.4;Undifferentiated cells: 381.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Group enriched" "Detected in many" 6 "Bile duct cancer: 110.2;breast cancer: 134.0;colorectal cancer: 162.6;Gastric cancer: 115.2;prostate cancer: 62.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Eccrine sweat gland cells" "Region enriched" "Detected in all" 8 "basal ganglia: 1243.8" "Region enriched" "Detected in all" 26 "basal ganglia: 1534.8" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "CAB004026: AB_2169007, HPA048630: AB_2680468, HPA061142: AB_2684438" "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" PRKCA "PKCA, PKCα" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.8" "Cell type enhanced" "Detected in all" "Astrocytes: 547.2;Bipolar cells: 208.0;Excitatory neurons: 244.2;Inhibitory neurons: 391.7;Microglial cells: 273.6;Oligodendrocyte precursor cells: 813.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 190000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Plasma membrane, Cytosol" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 147.9;Excitatory neurons: 389.0;Inhibitory neurons: 519.5;Late spermatids: 479.2;Oligodendrocyte precursor cells: 141.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 32: Neurons - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" PRXL2B "C1orf93, FAM213B, MGC26818" ENSG00000157870 "Peroxiredoxin like 2B" Q8TBF2 1 2586491-2591469 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 47.4;Proximal enterocytes: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006403 Approved Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" Cytosol Nucleoplasm "HPA006403: AB_1853870" "unprognostic (1.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (2.83e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.24e-3)" "unprognostic (2.76e-1)" "prognostic favorable (1.28e-4)" "unprognostic (5.22e-3)" "unprognostic (2.03e-1)" "unprognostic (7.91e-3)" "unprognostic (2.20e-2)" PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 232.0;Basal squamous epithelial cells: 49.3;Breast glandular cells: 102.2;Breast myoepithelial cells: 39.5;Club cells: 47.7;Ionocytes: 57.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 226.8" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 628.6" "Cell type enhanced" "Detected in many" "Astrocytes: 1104.6;Oligodendrocyte precursor cells: 1360.8;Oligodendrocytes: 4317.6" "Cancer enriched" "Detected in all" 6 "glioma: 42.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 15: Non-specific - Protein binding" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB022602: , HPA019123: AB_1855980" "unprognostic (2.42e-1)" "unprognostic (5.81e-2)" "unprognostic (1.31e-1)" "unprognostic (1.06e-2)" "unprognostic (8.57e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.76e-3)" "unprognostic (1.08e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.16e-1)" "unprognostic (3.86e-1)" "unprognostic (4.09e-2)" RAB3A ENSG00000105649 "RAB3A, member RAS oncogene family" P20336 19 18196784-18204042 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 290.7;retina: 77.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 78.4;Cone photoreceptor cells: 132.7;Horizontal cells: 102.5;Inhibitory neurons: 40.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 290.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 34.2" "Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, CAB009949, CAB078998" Enhanced Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "Centrosome, Cytosol" "CAB009949: AB_632292, CAB078998: , HPA003160: AB_1079731" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (6.80e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (1.13e-1)" "prognostic favorable (6.14e-7)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (6.14e-2)" RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase subunit beta" P53611 1 75786197-75795086 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 223.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: Non-specific - mRNA processing" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752, CAB080160, CAB080162" Supported Approved Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 5: Non-specific - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Nuclear bodies" "Nuclear speckles" "CAB080160: , CAB080162: , HPA006716: AB_2667650, HPA006724: AB_2667655, HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.73e-4)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 53.3;Excitatory neurons: 80.7;Horizontal cells: 96.1;Intestinal goblet cells: 122.3;Oligodendrocyte precursor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" RBFOX3 "FOX-3, HRNBP3, NeuN" ENSG00000167281 "RNA binding fox-1 homolog 3" A6NFN3 17 79089345-79516148 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.2;intestine: 97.4;urinary bladder: 80.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 316.0;Inhibitory neurons: 159.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Group enriched" "Detected in many" 4 "cerebellum: 217.2;cerebral cortex: 118.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.8;Neuroblastoma: 15.0" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030790, HPA075862, CAB078782" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "CAB078782: , HPA030790: AB_10602305, HPA075862: " "unprognostic (2.84e-1)" "unprognostic (1.88e-1)" "unprognostic (4.10e-2)" "unprognostic (9.23e-3)" "unprognostic (8.85e-2)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (7.72e-2)" "unprognostic (1.50e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.22e-15)" "unprognostic (8.92e-3)" "unprognostic (1.92e-1)" "unprognostic (1.61e-1)" "unprognostic (1.88e-1)" RCN2 "E6BP, ERC-55, ERC55, TCBP49" ENSG00000117906 "Reticulocalbin 2" Q14257 15 76931738-76954393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 321.5" "Cell type enhanced" "Detected in all" "Spermatocytes: 518.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030694, HPA030695" Enhanced Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 92000 "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 31: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA030694: AB_2673573, HPA030695: AB_2673574" "unprognostic (1.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (2.42e-1)" "unprognostic (8.71e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (1.74e-1)" "unprognostic (2.20e-2)" "unprognostic (4.61e-3)" "unprognostic (1.39e-1)" "unprognostic (1.98e-1)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (3.67e-2)" REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;choroid plexus: 77.8;retina: 61.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.7;Cone photoreceptor cells: 155.1;Excitatory neurons: 50.4;Horizontal cells: 62.2;Inhibitory neurons: 45.1;Rod photoreceptor cells: 60.2" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 35.2" "Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "dendritic cells: 48.0;Horizontal cells: 28.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 120.9;thyroid cancer: 39.8" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 222.9" "Cell type enhanced" "Detected in many" "granulocytes: 436.3;Hofbauer cells: 554.7;Langerhans cells: 384.6;Macrophages: 298.7;monocytes: 269.6;Schwann cells: 374.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004559, HPA021305" Enhanced Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 840000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 4: Platelets - Platelet activation" Nucleoplasm "Nuclear bodies" "CAB004559: AB_628216, HPA021305: AB_1856225" "unprognostic (1.64e-2)" "prognostic favorable (6.81e-4)" "unprognostic (7.98e-2)" "prognostic favorable (6.32e-4)" "unprognostic (5.21e-2)" "unprognostic (6.19e-2)" "unprognostic (4.32e-3)" "unprognostic (6.35e-2)" "unprognostic (9.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.20e-10)" "unprognostic (2.50e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (7.92e-3)" RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 452.7;Sertoli cells: 1998.5;Smooth muscle cells: 1501.8" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 848.3" "Adipose subcutaneous - Endothelial cells, Kidney - Fibroblasts, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" RGS9 "MGC111763, MGC26458, PERRS, RGS9L" ENSG00000108370 "Regulator of G protein signaling 9" O75916 17 65100812-65227703 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.5" "Group enriched" "Detected in many" 9 "Cone photoreceptor cells: 284.3;Rod photoreceptor cells: 493.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 9.7;MAIT T-cell: 2.5;memory CD8 T-cell: 6.8;naive CD8 T-cell: 3.2;NK-cell: 4.0" "Group enriched" "Detected in many" 42 "NK-cells: 4.0;T-cells: 9.7" "Cancer enhanced" "Detected in many" "lymphoma: 4.5" "Region enriched" "Detected in all" 9 "basal ganglia: 248.1" "Region enriched" "Detected in all" 10 "basal ganglia: 110.0" "HPA013550, HPA014137" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "HPA013550: , HPA014137: AB_2668943" "unprognostic (4.43e-3)" "unprognostic (7.49e-3)" "unprognostic (5.12e-2)" "unprognostic (3.09e-5)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (4.88e-2)" "prognostic favorable (1.35e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-2)" "unprognostic (4.94e-2)" "unprognostic (3.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.7;Distal enterocytes: 118.4;Langerhans cells: 254.6;NK-cells: 125.0;Proximal enterocytes: 102.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: AB_2732299" "unprognostic (1.26e-1)" "unprognostic (8.73e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-5)" "unprognostic (1.38e-3)" "unprognostic (2.37e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "unprognostic (1.10e-4)" "unprognostic (1.10e-1)" "unprognostic (5.01e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-2)" "unprognostic (7.51e-4)" "unprognostic (1.14e-1)" RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 359.8;Cone photoreceptor cells: 634.2;Excitatory neurons: 1566.3;Inhibitory neurons: 1205.7;Oligodendrocyte precursor cells: 552.6;Rod photoreceptor cells: 1072.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "retina: 265.6" "Cell type enriched" "Detected in some" 67 "Muller glia cells: 2878.4" "Group enriched" "Detected in some" 30 "glioma: 3.7;melanoma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Bile duct cancer: 10.1;colorectal cancer: 5.3;skin cancer: 7.9" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 68: Muller glia cells - Visual perception" Cytosol "Nucleoplasm, Centrosome" "HPA042051: AB_2732495, HPA044083: AB_2678802" "unprognostic (3.19e-2)" "unprognostic (2.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (5.21e-2)" "unprognostic (3.17e-1)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (8.42e-2)" RPGRIP1 "CORD13, LCA6, RGI1, RPGRIP" ENSG00000092200 "RPGR interacting protein 1" Q96KN7 14 21280083-21351301 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Glaucoma, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 80 "retina: 185.3;testis: 59.6" "Group enriched" "Detected in some" 21 "Cone photoreceptor cells: 129.2;Early spermatids: 172.5;Late spermatids: 124.6;Rod photoreceptor cells: 130.8;Spermatocytes: 43.9" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 8.8" "Group enriched" "Detected in many" 18 "dendritic cells: 3.3;granulocytes: 8.8;monocytes: 3.7" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042955, HPA060190" Supported Supported NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "HPA042955: AB_2678239, HPA060190: AB_2684218" "unprognostic (9.02e-4)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" "unprognostic (1.86e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (2.92e-1)" "unprognostic (1.99e-1)" "unprognostic (3.94e-3)" "unprognostic (2.33e-1)" "unprognostic (7.31e-3)" "unprognostic (2.86e-2)" "unprognostic (2.87e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-2)" RPL9 L9 ENSG00000163682 "Ribosomal protein L9" P32969 4 39452587-39458931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 2512.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003372 Approved Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 180000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 57: Non-specific - Translation" "Cluster 39: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA003372: AB_1079843" "unprognostic (1.08e-3)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" "unprognostic (8.06e-3)" "unprognostic (5.59e-2)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (8.58e-2)" "unprognostic (6.68e-2)" "unprognostic (2.50e-2)" "unprognostic (7.85e-2)" "prognostic unfavorable (7.34e-4)" "unprognostic (1.34e-1)" "unprognostic (2.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-2)" RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.2;Enteroendocrine cells: 22.1;Excitatory neurons: 45.5;Horizontal cells: 44.2;Inhibitory neurons: 29.7;Late spermatids: 84.7" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 46.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enriched" "Detected in many" 6 "Schwann cells: 1902.7" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Cancer enriched" "Detected in many" 8 "skin cancer: 1209.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Stomach - Fibroblasts" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115186 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.5" "Cell type enhanced" "Detected in many" "Early spermatids: 159.8;Spermatocytes: 193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: Non-specific - Protein binding" "Cluster 31: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (8.25e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-3)" "unprognostic (5.34e-3)" "unprognostic (2.60e-1)" "unprognostic (2.57e-3)" "unprognostic (5.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.92e-4)" "unprognostic (8.44e-3)" "unprognostic (7.56e-2)" "unprognostic (3.12e-2)" "unprognostic (4.99e-2)" SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 143.3;Enteroendocrine cells: 292.6;Horizontal cells: 117.9;Inhibitory neurons: 106.8;Pancreatic endocrine cells: 441.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 317.4;Rhabdoid: 443.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Cell type enhanced" "Detected in some" "Astrocytes: 76.9;Bipolar cells: 118.4;Cone photoreceptor cells: 253.3;Enteroendocrine cells: 64.3;Horizontal cells: 92.3;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 60.7;Pancreatic endocrine cells: 161.4;Rod photoreceptor cells: 83.6" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 59.4;thyroid cancer: 97.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatocytes, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 35: Bipolar cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" SCGN "CALBL, DJ501N12.8, SECRET, SEGN" ENSG00000079689 "Secretagogin, EF-hand calcium binding protein" O76038 6 25652201-25701783 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.5;pancreas: 67.1;pituitary gland: 38.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 103.9;Enteroendocrine cells: 483.2;Pancreatic endocrine cells: 130.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 38.2;renal cancer: 22.6" "Group enriched" "Detected in many" 4 "cerebellum: 23.6;hippocampal formation: 14.5;hypothalamus: 43.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 9.2;liver cancer: 7.0;lung cancer: 22.1;Neuroblastoma: 7.2;prostate cancer: 11.3;thyroid cancer: 7.5" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 16 "olfactory bulb: 82.0" "Region enriched" "Detected in some" 9 "olfactory bulb: 137.1" "CAB004005, HPA006641, CAB044060, CAB062563, CAB068232" Enhanced Supported Supported Cytosol "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 55: Endocrine cells - Hormone signaling" Cytosol "CAB004005: , CAB044060: , CAB062563: AB_2665612, CAB068232: AB_2665613, HPA006641: AB_1079874" "unprognostic (8.15e-2)" "unprognostic (4.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.25e-2)" "unprognostic (4.70e-1)" "unprognostic (1.78e-2)" "unprognostic (2.01e-1)" "unprognostic (5.14e-2)" "unprognostic (5.41e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-1)" SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 301.5;Proximal enterocytes: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" SEC22B "ERS-24, SEC22L1" ENSG00000265808 "SEC22 homolog B, vesicle trafficking protein" O75396 1 120150898-120176520 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079017 Approved NA NA 91000 "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 38: Non-specific - mRNA processing" "Cluster 65: Fibroblasts - ECM organization" "CAB079017: " "unprognostic (2.21e-1)" "unprognostic (2.29e-2)" "unprognostic (5.02e-2)" "unprognostic (8.52e-2)" "unprognostic (1.13e-1)" "unprognostic (7.88e-2)" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "prognostic favorable (4.58e-4)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.34e-4)" "unprognostic (5.80e-2)" "unprognostic (2.48e-1)" "unprognostic (1.52e-2)" "unprognostic (2.15e-1)" SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.7;Excitatory neurons: 10.3;Extravillous trophoblasts: 31.9;Horizontal cells: 25.0;Late spermatids: 37.6;Schwann cells: 12.0" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.8;retina: 75.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 75.1;Cone photoreceptor cells: 63.8;Excitatory neurons: 385.0;Inhibitory neurons: 138.0;Late spermatids: 48.2" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 12.7" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: AB_628099, HPA026685: AB_1856817, HPA063573: AB_2685045" "unprognostic (4.78e-2)" "unprognostic (3.24e-2)" "unprognostic (1.68e-2)" "unprognostic (5.05e-5)" "unprognostic (4.23e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (5.90e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-3)" "unprognostic (8.76e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.68e-12)" "unprognostic (2.65e-2)" "unprognostic (8.29e-2)" "unprognostic (2.25e-2)" "unprognostic (8.44e-2)" SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 128.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "classical monocyte: 19.7;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943, HPA075224" Enhanced Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 61: Liver - Metabolism" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA037942: AB_2675748, HPA037943: AB_10671637, HPA075224: " "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" "unprognostic (6.77e-3)" "unprognostic (2.81e-1)" "unprognostic (7.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.08e-6)" SLC10A4 MGC29802 ENSG00000145248 "Solute carrier family 10 member 4" Q96EP9 4 48483343-48489526 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 36.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.4;Early spermatids: 3.2;Erythroid cells: 2.7;Horizontal cells: 3.8;Inhibitory neurons: 15.7;Late spermatids: 4.9;Oligodendrocyte precursor cells: 3.9" "Group enriched" "Detected in many" 4 "endometrial cancer: 1.8;glioma: 5.9" "Region enhanced" "Detected in many" "midbrain: 36.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 46.7" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 26.2;hypothalamus: 10.7;midbrain: 26.5;pons and medulla: 13.2;thalamus: 8.4" "Group enriched" "Detected in many" 5 "basal ganglia: 14.2;midbrain: 56.7;pons: 23.5;spinal cord: 44.7" HPA028835 Uncertain Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "HPA028835: AB_10603025" "unprognostic (4.06e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (3.05e-3)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (5.41e-2)" "unprognostic (3.67e-1)" "unprognostic (1.86e-1)" "unprognostic (4.08e-3)" "unprognostic (9.98e-3)" "unprognostic (1.46e-1)" "unprognostic (3.50e-1)" "unprognostic (5.14e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (8.73e-2)" SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.1;Cone photoreceptor cells: 153.4;Granulosa cells: 341.7;Muller glia cells: 169.9;Rod photoreceptor cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: BEWO - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: AB_2686337" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavorable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" SLC17A6 "DNPI, VGLUT2" ENSG00000091664 "Solute carrier family 17 member 6" Q9P2U8 11 22338381-22379503 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 39.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 14.3;Horizontal cells: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.5;skin cancer: 1.3" "Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "basal ganglia: 51.9;hypothalamus: 139.9;midbrain: 172.4;pons and medulla: 86.4;thalamus: 164.9" "Low region specificity" "Detected in many" "CAB037130, HPA039226, CAB078204" Supported Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 38: Neurons - Neuronal signaling" "CAB037130: AB_477611, CAB078204: AB_2665794, HPA039226: AB_2676400" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "brain: 405.4;retina: 315.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 358.5;Cone photoreceptor cells: 489.4;Excitatory neurons: 106.3;Rod photoreceptor cells: 397.2" "Cancer enriched" "Detected in some" 6 "glioma: 7.5" "Group enriched" "Detected in many" 7 "amygdala: 176.7;basal ganglia: 243.4;cerebral cortex: 289.7;hippocampal formation: 405.4;white matter: 169.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 15.4" "Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 201.2;cerebellum: 204.6;cerebral cortex: 339.5;hippocampal formation: 471.2" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "CAB037183: AB_261840, HPA050458: AB_2681134, HPA063679: AB_2685086" "unprognostic (1.79e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (9.12e-2)" "unprognostic (3.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.32e-2)" "unprognostic (6.61e-2)" "unprognostic (4.26e-12)" "unprognostic (8.36e-4)" "unprognostic (4.27e-1)" "unprognostic (1.35e-2)" "unprognostic (6.17e-3)" SLC17A8 "DFNA25, VGLUT3" ENSG00000179520 "Solute carrier family 17 member 8" Q8NDX2 12 100357074-100422055 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 11.3;intestine: 5.2" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 11.4;Extravillous trophoblasts: 4.4;Inhibitory neurons: 6.4;Proximal enterocytes: 34.5" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 5 "basal ganglia: 11.3;midbrain: 8.3;pons: 6.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038870, CAB079058" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 45: Intestine - Brush border" "Cluster 56: Neurons - Neuronal signaling" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Endoplasmic reticulum" "CAB079058: , HPA038870: " "unprognostic (4.52e-3)" "unprognostic (2.18e-1)" "unprognostic (8.56e-2)" "unprognostic (1.32e-3)" "unprognostic (3.65e-1)" "unprognostic (7.67e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-2)" "unprognostic (8.89e-2)" "unprognostic (3.55e-1)" SLC18A3 VACHT ENSG00000187714 "Solute carrier family 18 member A3" Q16572 10 49610310-49612720 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 25.6" "Cell type enriched" "Detected in single" 4 "Smooth muscle cells: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "liver cancer: 4.1;Neuroblastoma: 12.8" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 78.1" CAB079011 Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB079011: " "unprognostic (2.14e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (9.39e-2)" "unprognostic (4.55e-2)" "unprognostic (3.00e-1)" "unprognostic (5.85e-3)" "unprognostic (7.56e-2)" "unprognostic (1.16e-1)" SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1681.2;Microglial cells: 323.8;Muller glia cells: 519.5;Oligodendrocyte precursor cells: 227.7;Oligodendrocytes: 235.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.3;Early spermatids: 31.9;Extravillous trophoblasts: 12.4;Horizontal cells: 10.9;Late spermatids: 36.7;Syncytiotrophoblasts: 44.6" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 9.7;breast cancer: 9.8" "Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 813.1;Extravillous trophoblasts: 578.1;Muller glia cells: 361.2;Syncytiotrophoblasts: 2405.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Early spermatids: 15.9;Excitatory neurons: 15.4;Late spermatids: 34.8;Peritubular cells: 10.6;Sertoli cells: 13.8;Spermatocytes: 13.0;Spermatogonia: 9.8" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 7.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Sertoli cells" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" SLC32A1 "bA122O1.1, VGAT, VIAAT" ENSG00000101438 "Solute carrier family 32 member 1" Q9H598 20 38724486-38729372 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 39.8" "Group enriched" "Detected in some" 14 "dendritic cells: 69.2;Horizontal cells: 64.1;Inhibitory neurons: 20.2" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037156, HPA058859, HPA059985" Enhanced Supported Uncertain Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Cytosol "CAB037156: AB_532294, HPA058859: AB_2683836, HPA059985: AB_2684187" "unprognostic (1.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 374.1;Cardiomyocytes: 308.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 1: T-cells - Immune response" "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 153.3" "Cell type enhanced" "Detected in some" "Astrocytes: 82.6;Excitatory neurons: 13.5;Horizontal cells: 21.1;Inhibitory neurons: 25.0;Muller glia cells: 23.0;Oligodendrocyte precursor cells: 22.1" "Cancer enhanced" "Detected in many" "glioma: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm Vesicles "HPA037981: AB_10671383" "unprognostic (6.04e-2)" "unprognostic (8.01e-2)" "unprognostic (1.21e-7)" "unprognostic (8.60e-2)" "unprognostic (8.68e-2)" "unprognostic (9.72e-3)" "unprognostic (6.39e-3)" "unprognostic (9.77e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-3)" "unprognostic (6.06e-2)" "unprognostic (4.44e-2)" "unprognostic (9.83e-2)" "unprognostic (2.31e-2)" SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655604-55706192 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 149.4" "Group enriched" "Detected in some" 6 "Early spermatids: 3.5;Extravillous trophoblasts: 9.5;Late spermatids: 4.8;Spermatocytes: 8.4;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.9" "Region enriched" "Detected in some" 10 "pons: 149.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 54 "Neuroblastoma: 104.8" "Kidney - Intercalated cells, Testis - Early spermatids" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 13.8" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 54: Extravillous trophoblasts - Unknown function" Cytosol Mitochondria "CAB078195: AB_2665806, HPA004057: AB_1080012, HPA076311: AB_2732307" "unprognostic (9.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.26e-4)" "unprognostic (4.07e-1)" "unprognostic (4.16e-1)" "unprognostic (8.38e-2)" "unprognostic (2.97e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.95e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (8.48e-2)" "unprognostic (1.43e-2)" SLC6A3 "DAT, DAT1" ENSG00000142319 "Solute carrier family 6 member 3" Q01959 5 1392794-1445440 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "brain: 60.6" "Cell type enhanced" "Detected in single" "Serous glandular cells: 2.2" "Cancer enriched" "Detected in some" 18 "renal cancer: 25.7" "Region enriched" "Detected in some" 26 "midbrain: 60.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Kidney cancer: 3.3" "Adipose visceral - Mesothelial cells" "Group enriched" "Detected in many" 8 "midbrain: 80.6;thalamus: 29.0" "Region enriched" "Detected in some" 152 "midbrain: 302.6" "HPA012763, HPA013602, CAB016249, CAB078172" Enhanced Supported Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Kidney - Mixed function" "Cluster 61: Non-specific - Transcription" Vesicles "CAB016249: AB_627402, CAB078172: AB_2665810, HPA012763: AB_2732405, HPA013602: AB_1847484" "unprognostic (2.25e-4)" "unprognostic (2.22e-1)" "unprognostic (8.45e-2)" "unprognostic (5.24e-2)" "unprognostic (7.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.64e-5)" "unprognostic (9.31e-2)" "unprognostic (7.89e-2)" "unprognostic (4.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (3.40e-7)" "unprognostic (6.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.22e-2)" "unprognostic (4.74e-2)" SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 232.0" "Group enriched" "Detected in many" 10 "Cytotrophoblasts: 120.7;Proximal enterocytes: 101.8;Syncytiotrophoblasts: 96.9" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Group enriched" "Detected in some" 11 "midbrain: 232.0;pons: 86.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8;liver cancer: 1.7" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 7 "midbrain: 38.9;pons: 29.1" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: BEWO - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (7.45e-2)" "unprognostic (7.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.72e-4)" "unprognostic (2.07e-1)" "unprognostic (8.42e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-3)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (4.98e-2)" "unprognostic (1.76e-1)" "unprognostic (4.05e-2)" "unprognostic (7.18e-2)" SLC6A5 "GLYT2, NET1" ENSG00000165970 "Solute carrier family 6 member 5" Q9Y345 11 20599594-20659285 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "brain: 22.2" "Cell type enriched" "Detected in some" 7 "Late spermatids: 72.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "medulla oblongata: 22.2;pons: 20.0;spinal cord: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Uterine cancer: 1.9" "Testis - Late spermatids" "Region enriched" "Detected in some" 9 "pons and medulla: 49.3" "Group enriched" "Detected in many" 8 "medulla oblongata: 30.5;spinal cord: 18.3" CAB079052 Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 47: Retina - Visual perception" "Cluster 51: Late spermatids - Spermatogenesis" "CAB079052: " "unprognostic (6.94e-2)" "unprognostic (2.28e-1)" "unprognostic (4.75e-2)" SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10218830-10307418 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 20 "brain: 1658.7;retina: 492.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 466.1;Cone photoreceptor cells: 315.4;Excitatory neurons: 1001.9;Horizontal cells: 240.3;Inhibitory neurons: 539.9" "Cancer enriched" "Detected in many" 4 "glioma: 28.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 54.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane" NA NA 9000 "Cluster 6: Brain - Smell perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" Vesicles "CAB000360: AB_2286342, HPA001830: AB_1080039, HPA071013: " "unprognostic (1.64e-3)" "unprognostic (7.26e-3)" "unprognostic (4.36e-2)" "unprognostic (2.49e-7)" "unprognostic (6.86e-3)" "unprognostic (5.87e-3)" "unprognostic (1.15e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (5.82e-3)" "unprognostic (4.80e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-3)" "unprognostic (2.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.02e-2)" SNCB ENSG00000074317 "Synuclein beta" Q16143 5 176620082-176630556 "Human disease related genes, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 439.2;retina: 182.2" "Group enriched" "Detected in some" 7 "Bipolar cells: 94.3;Cone photoreceptor cells: 93.1;Excitatory neurons: 36.4;Horizontal cells: 71.8;Inhibitory neurons: 31.8;Rod photoreceptor cells: 47.2" "Cancer enriched" "Detected in some" 8 "glioma: 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002681, HPA035876" Enhanced Supported NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 44: Photoreceptor cells - Visual perception" "CAB002681: , HPA035876: AB_10670592" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (3.41e-1)" "unprognostic (2.39e-1)" "unprognostic (2.29e-3)" "unprognostic (3.31e-1)" "unprognostic (5.41e-5)" "unprognostic (1.31e-3)" "unprognostic (8.57e-2)" "unprognostic (2.81e-1)" "unprognostic (8.42e-3)" SNCG "BCSG1, persyn, SR" ENSG00000173267 "Synuclein gamma" O76070 10 86958599-86963258 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 268.3;brain: 411.2" "Cell type enhanced" "Detected in many" "Adipocytes: 189.0;Basal prostatic cells: 237.2;Breast myoepithelial cells: 181.0;Club cells: 373.8;Endothelial cells: 170.9;Horizontal cells: 185.9;Smooth muscle cells: 252.1" "Group enriched" "Detected in all" 8 "ovarian cancer: 84.1;urothelial cancer: 301.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 225.1" "Liver - Vascular Endothelial cells, Skeletal muscle - Smooth muscle cells" "Region enhanced" "Detected in all" "pons and medulla: 279.9" "Low region specificity" "Detected in many" "CAB001452, HPA014404, CAB040581, CAB080022" Enhanced Supported Supported Centrosome NA NA 23000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 72: Smooth muscle cells - ECM organization" Centrosome "CAB001452: AB_564020, CAB040581: , CAB080022: , HPA014404: AB_1857715" "unprognostic (2.06e-1)" "unprognostic (2.58e-1)" "unprognostic (6.87e-3)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (4.76e-3)" "unprognostic (8.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-3)" "unprognostic (3.75e-1)" "prognostic unfavorable (2.29e-8)" "prognostic unfavorable (7.15e-4)" "unprognostic (2.35e-1)" "unprognostic (2.36e-2)" "unprognostic (3.77e-3)" SOX2 ENSG00000181449 "SRY-box transcription factor 2" P48431 3 181711925-181714436 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.2;esophagus: 24.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 288.3;Muller glia cells: 310.6;Respiratory ciliated cells: 83.5;Schwann cells: 124.5;Squamous epithelial cells: 212.2" "Cancer enhanced" "Detected in many" "glioma: 136.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "HPA045725, HPA062851, HPA071379, CAB079745" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "CAB079745: , HPA045725: AB_2679431, HPA062851: , HPA071379: " "unprognostic (1.80e-2)" "unprognostic (3.18e-3)" "unprognostic (5.69e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-3)" "unprognostic (1.60e-1)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (1.71e-1)" "unprognostic (4.38e-3)" "unprognostic (1.83e-1)" "unprognostic (7.68e-2)" "unprognostic (3.81e-9)" "unprognostic (1.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" SP3 SPR-2 ENSG00000172845 "Sp3 transcription factor" Q02447 2 173880850-173965702 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004580, HPA032145, HPA032146" Supported Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm Cytosol "CAB004580: AB_628274, HPA032145: , HPA032146: AB_2732465" "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (2.39e-3)" "unprognostic (2.50e-1)" "unprognostic (4.92e-2)" "unprognostic (5.54e-3)" "unprognostic (6.36e-2)" "unprognostic (2.76e-3)" "unprognostic (3.27e-1)" "unprognostic (5.01e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.46e-5)" "unprognostic (2.78e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.69e-1)" SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Cell type enriched" "Detected in some" 33 "Enteroendocrine cells: 4790.0" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 133.3;thyroid cancer: 474.4" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Inner root sheath cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 137.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 36.3;Horizontal cells: 53.2;Inhibitory neurons: 30.4;Late spermatids: 14.4" "Cancer enriched" "Detected in some" 7 "glioma: 5.1" "Region enhanced" "Detected in many" "cerebral cortex: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.8" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Vesicles "Nuclear membrane" "CAB079008: , HPA069176: AB_2686098" "unprognostic (1.43e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-4)" "unprognostic (3.90e-3)" "unprognostic (3.98e-2)" "unprognostic (1.90e-2)" "unprognostic (2.21e-3)" "unprognostic (2.53e-2)" "unprognostic (1.72e-1)" "unprognostic (3.72e-3)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (1.57e-2)" STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 133.4;Endometrial ciliated cells: 93.6;Late spermatids: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 68: Kidney - Mixed function" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" STXBP5 "LLGL3, tomosyn" ENSG00000164506 "Syntaxin binding protein 5" Q5T5C0 6 147204425-147390476 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 115.8" "Cell type enhanced" "Detected in many" "Astrocytes: 315.7;Excitatory neurons: 435.4;Inhibitory neurons: 293.5;Oligodendrocyte precursor cells: 197.4;Oligodendrocytes: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 3.8;eosinophil: 9.2;neutrophil: 3.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 9.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039991, HPA049727, CAB079016" Enhanced Supported Enhanced Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 62: Granulocytes - Innate immune response" "Cluster 38: Neurons - Neuronal signaling" Cytosol "CAB079016: , HPA039991: AB_10673368, HPA049727: AB_2680863" "prognostic unfavorable (4.48e-4)" "unprognostic (4.60e-3)" "unprognostic (2.28e-3)" "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (1.52e-1)" "unprognostic (9.56e-4)" "unprognostic (6.01e-2)" "unprognostic (3.60e-1)" "unprognostic (2.74e-2)" "unprognostic (1.70e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.74e-7)" "unprognostic (8.01e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-1)" "unprognostic (1.35e-3)" SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 207.4;Early spermatids: 225.4;Late spermatids: 315.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: Non-specific - Nuclear processes" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 96.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 333.5;Inhibitory neurons: 531.1;Oligodendrocyte precursor cells: 122.7" "Cancer enhanced" "Detected in many" "glioma: 4.5" "Group enriched" "Detected in many" 5 "amygdala: 67.0;basal ganglia: 77.7;cerebral cortex: 96.8;hippocampal formation: 92.9;white matter: 44.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Neuroblastoma: 21.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "CAB079005: , HPA037012: AB_2675431" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (7.54e-2)" "unprognostic (9.87e-3)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (6.32e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (9.77e-2)" "unprognostic (4.89e-4)" "unprognostic (9.94e-2)" "unprognostic (7.35e-2)" "unprognostic (1.78e-2)" SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" SYNJ2BP-COX16 ENSG00000258644 "SYNJ2BP-COX16 readthrough" 14 70326064-70417074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 9.6;Distal tubular cells: 12.4;Glandular and luminal cells: 13.2;Hepatocytes: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000866, HPA062659" Approved Supported Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 69: BICR 18 - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Mitochondria "HPA000866: AB_2276678, HPA062659: AB_2684823" "unprognostic (9.44e-2)" "unprognostic (2.42e-1)" "unprognostic (4.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (8.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.96e-2)" "unprognostic (3.00e-1)" "unprognostic (2.21e-2)" "unprognostic (6.41e-2)" "unprognostic (6.73e-4)" "unprognostic (6.68e-2)" "unprognostic (6.93e-2)" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" SYP MRX96 ENSG00000102003 Synaptophysin P08247 X 49187815-49200199 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 259.4;pituitary gland: 106.8;retina: 316.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 478.9;Cone photoreceptor cells: 468.7;Horizontal cells: 239.7;Rod photoreceptor cells: 599.0" "Group enriched" "Detected in many" 6 "glioma: 12.8;pancreatic cancer: 5.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 56.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000076, HPA002858, CAB055505, CAB078999, HPA079659" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "CAB000076: AB_2315411, CAB055505: AB_564017, CAB078999: , HPA002858: AB_1080153, HPA079659: " "unprognostic (2.08e-1)" "unprognostic (8.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.37e-3)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.87e-1)" "unprognostic (6.46e-5)" "unprognostic (8.52e-3)" "unprognostic (1.62e-1)" "unprognostic (3.44e-3)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.94e-1)" SYT1 "P65, SVP65, SYT" ENSG00000067715 "Synaptotagmin 1" P21579 12 78863993-79452008 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 403.3;retina: 197.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 1074.2;Cone photoreceptor cells: 1132.2;Excitatory neurons: 3698.0;Horizontal cells: 806.2;Inhibitory neurons: 2844.8;Rod photoreceptor cells: 867.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 10 "amygdala: 113.1;basal ganglia: 153.7;cerebral cortex: 403.3;hippocampal formation: 134.2;white matter: 146.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.0;naive B-cell: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 56.2" "Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008394, HPA064788" Enhanced Supported NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "HPA008394: AB_1857696, HPA064788: AB_2685351" "unprognostic (1.02e-3)" "unprognostic (2.55e-1)" "unprognostic (4.21e-3)" "unprognostic (3.77e-2)" "unprognostic (3.16e-2)" "unprognostic (3.68e-5)" "unprognostic (2.78e-2)" "unprognostic (1.83e-2)" "unprognostic (7.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (6.14e-3)" "unprognostic (3.05e-8)" "unprognostic (2.89e-2)" "unprognostic (8.26e-2)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" SYT2 ENSG00000143858 "Synaptotagmin 2" Q8N9I0 1 202590596-202710454 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Differentiation "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 73.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 22.9;Horizontal cells: 28.2;Inhibitory neurons: 22.2;Oligodendrocytes: 7.0" "Cancer enriched" "Detected in some" 7 "testis cancer: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 8.2" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063655 Enhanced Supported NA NA "Cluster 70: Brain - Nervous system development" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" "HPA063655: AB_2685077" "unprognostic (1.32e-2)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (2.24e-2)" "unprognostic (3.00e-1)" "unprognostic (2.35e-3)" "unprognostic (8.81e-3)" "unprognostic (1.17e-1)" "unprognostic (1.53e-2)" "unprognostic (6.33e-2)" "unprognostic (1.56e-2)" "unprognostic (6.23e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (5.17e-3)" TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 431.7" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 12.9;Extravillous trophoblasts: 39.6;Inhibitory neurons: 38.8;Syncytiotrophoblasts: 23.9" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;testis cancer: 13.5" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" NA NA 130000 "Cluster 28: Placenta - Pregnancy" "Cluster 6: BEWO - Unknown function" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" TBC1D25 OATL1 ENSG00000068354 "TBC1 domain family member 25" Q3MII6 X 48539714-48562609 "Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029197 Approved Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 7: NK-cells - Immune response regulation" "HPA029197: AB_2672945" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (5.12e-3)" "unprognostic (1.19e-1)" "unprognostic (9.18e-3)" "unprognostic (1.73e-2)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (7.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.57e-1)" "unprognostic (1.21e-1)" "unprognostic (8.07e-2)" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" TBL3 "SAZD, UTP13" ENSG00000183751 "Transducin beta like 3" Q12788 16 1972053-1982929 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 84.2;Late spermatids: 84.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042562, HPA055695" Enhanced Supported Enhanced Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 8: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" Nucleoli "HPA042562: AB_10964911, HPA055695: AB_2682888" "unprognostic (1.96e-1)" "unprognostic (5.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.56e-1)" "unprognostic (4.67e-1)" "unprognostic (2.65e-1)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (3.78e-2)" "unprognostic (8.03e-2)" "unprognostic (2.14e-2)" "unprognostic (8.32e-2)" "prognostic favorable (7.33e-4)" "unprognostic (3.65e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.77e-1)" TBR1 ENSG00000136535 "T-box brain transcription factor 1" Q16650 2 161416297-161425870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 29.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 64.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 196 "amygdala: 9.2;basal ganglia: 27.4;cerebral cortex: 29.1;hippocampal formation: 13.0;white matter: 19.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.5;Rhabdoid: 2.3" "Testis - Late spermatids" "Group enriched" "Detected in many" 6 "amygdala: 44.6;basal ganglia: 28.3;cerebral cortex: 70.8;hippocampal formation: 45.7;white matter: 43.9" "Region enhanced" "Detected in many" "cerebral cortex: 66.9" "HPA051256, HPA078644, HPA078657" Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 47: Retina - Visual perception" "Cluster 9: Neurons - Nervous system development" "HPA051256: , HPA078644: AB_2732387, HPA078657: AB_2732388" "unprognostic (3.08e-2)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-2)" "unprognostic (7.43e-3)" "unprognostic (1.95e-1)" "unprognostic (1.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.39e-9)" "unprognostic (5.72e-2)" "unprognostic (1.72e-1)" "unprognostic (5.37e-2)" TH DYT5b ENSG00000180176 "Tyrosine hydroxylase" P07101 11 2163929-2171815 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis, Neurotransmitter biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "adrenal gland: 196.6;brain: 270.9" "Group enriched" "Detected in some" 4 "Endometrial stromal cells: 9.5;Extravillous trophoblasts: 15.5" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 4.0" "Group enriched" "Detected in many" 5 "midbrain: 192.4;pons: 270.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Brain cancer: 32.5;Neuroblastoma: 44.0" "Pancreas - Beta cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "olfactory bulb: 178.8" "Region enriched" "Detected in many" 20 "midbrain: 594.4" "CAB002522, HPA013768, HPA014010, HPA061003, CAB072340" Enhanced Supported Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 54: Extravillous trophoblasts - Unknown function" Cytosol "CAB002522: AB_564047, CAB072340: , HPA013768: , HPA014010: , HPA061003: AB_2630374" "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.75e-4)" "unprognostic (8.82e-3)" "unprognostic (5.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-3)" "unprognostic (3.83e-2)" "unprognostic (4.39e-4)" "unprognostic (4.97e-1)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "unprognostic (2.18e-2)" TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 79.7;Bipolar cells: 79.7;Ductal cells: 85.3;Horizontal cells: 156.4;Muller glia cells: 164.7;Rod photoreceptor cells: 171.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 65: Breast cancer - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 67.8;pituitary gland: 18.3;retina: 28.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.6;Cone photoreceptor cells: 25.8;Excitatory neurons: 26.1;Horizontal cells: 78.8;Inhibitory neurons: 53.1;Rod photoreceptor cells: 28.8" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 6.8;neutrophil: 14.2" "Lineage enriched" "Detected in many" 11 "granulocytes: 14.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 22.6" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.4;Excitatory neurons: 14.8;Horizontal cells: 16.7;Inhibitory neurons: 24.1;Oligodendrocyte precursor cells: 12.5;Peritubular cells: 20.3;Theca cells: 26.2" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 181.1;Granulosa cells: 121.3;Spermatocytes: 638.1;Spermatogonia: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 46: Non-specific - Unknown function" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" TPRG1L "FAM79A, FLJ21811, RP11-46F15.3" ENSG00000158109 "Tumor protein p63 regulated 1 like" Q5T0D9 1 3625015-3630127 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063163, CAB079051" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 45: Intestine - Brush border" "Cluster 38: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" Vesicles "Plasma membrane" "CAB079051: , HPA063163: AB_2684953" "unprognostic (1.92e-1)" "unprognostic (3.26e-3)" "unprognostic (4.46e-2)" "unprognostic (7.99e-2)" "unprognostic (4.50e-2)" "unprognostic (3.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-3)" "prognostic favorable (1.76e-9)" "unprognostic (1.53e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 72.5;Suprabasal keratinocytes: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: Non-specific - Cilium assembly" "Cluster 18: Non-specific - Mixed function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" U2AF2 U2AF65 ENSG00000063244 "U2 small nuclear RNA auxiliary factor 2" P26368 19 55654146-55674716 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010910, HPA041943, HPA043562" Supported Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 73000 "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 4: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "CAB010910: AB_262122, HPA041943: AB_2677760, HPA043562: AB_2678555" "unprognostic (2.37e-1)" "unprognostic (2.22e-1)" "unprognostic (3.12e-1)" "unprognostic (9.60e-2)" "unprognostic (6.94e-2)" "unprognostic (4.01e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (9.46e-2)" "unprognostic (1.36e-2)" "unprognostic (8.00e-2)" "unprognostic (3.33e-2)" "unprognostic (4.25e-3)" "unprognostic (2.19e-2)" "unprognostic (4.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.14e-1)" "unprognostic (3.08e-2)" UBTF "NOR-90, UBF, UBF1, UBF2" ENSG00000108312 "Upstream binding transcription factor" P17480 17 44205033-44221626 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004611, HPA006385" Supported Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 65: Breast cancer - Unknown function" "Cluster 16: Non-specific - RNA binding" "Nucleoli fibrillar center" "CAB004611: AB_671403, HPA006385: AB_1080447" "unprognostic (1.37e-3)" "unprognostic (1.12e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-1)" "unprognostic (8.54e-3)" "unprognostic (1.35e-3)" "unprognostic (4.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-1)" "unprognostic (1.96e-3)" "unprognostic (5.44e-2)" "unprognostic (9.01e-2)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 692.7;pituitary gland: 285.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 131.9;Distal tubular cells: 230.1;Excitatory neurons: 145.0;Horizontal cells: 180.7;Inhibitory neurons: 115.6;Pancreatic endocrine cells: 123.7;Spermatogonia: 97.5" "Cancer enhanced" "Detected in all" "glioma: 129.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 500000 "Cluster 43: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.93e-4)" USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 169.6;Horizontal cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 48: Non-specific - RNA binding" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881828 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (2.48e-4)" "prognostic favorable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favorable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favorable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: Non-specific - RNA binding" "Cluster 61: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.35e-5)" USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 65: Breast cancer - Unknown function" "Cluster 1: T-cells - Immune response" "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" USP39 "CGI-21, SAD1, SNRNP65" ENSG00000168883 "Ubiquitin specific peptidase 39" Q53GS9 2 85602856-85649283 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034823, HPA077350" Supported Supported Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA034823: AB_10602488, HPA077350: " "unprognostic (1.10e-2)" "unprognostic (3.31e-3)" "unprognostic (1.83e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.46e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (2.84e-6)" "unprognostic (1.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (5.17e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (4.05e-7)" "unprognostic (3.95e-3)" "unprognostic (2.25e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-1)" VAMP1 "SYB1, VAMP-1" ENSG00000139190 "Vesicle associated membrane protein 1" P23763 12 6462237-6470677 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 192.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 22.3;Inhibitory neurons: 24.5;Oligodendrocytes: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002779, CAB016119, CAB079000" Approved Supported NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 1: T-cells - Immune response" "CAB002779: , CAB016119: AB_628309, CAB079000: " "unprognostic (2.33e-1)" "unprognostic (6.72e-3)" "prognostic unfavorable (6.37e-5)" "unprognostic (8.09e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.22e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.40e-3)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.04e-11)" "unprognostic (1.47e-2)" "unprognostic (5.99e-2)" "unprognostic (1.62e-1)" "unprognostic (3.65e-2)" VAMP2 "SYB2, VAMP-2" ENSG00000220205 "Vesicle associated membrane protein 2" P63027 17 8159149-8163546 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 1051.7;Cone photoreceptor cells: 1142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" CAB078785 Supported NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 49: Non-specific - Unknown function" "Cluster 35: Bipolar cells - Visual perception" "CAB078785: " "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (1.58e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (7.28e-2)" "unprognostic (5.15e-2)" "unprognostic (1.55e-1)" "prognostic favorable (3.83e-6)" "unprognostic (8.27e-2)" "prognostic favorable (9.76e-8)" "unprognostic (1.21e-2)" "unprognostic (7.00e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 78.3;Melanocytes: 27.9" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 31 "breast cancer: 34.9;Neuroblastoma: 132.3" "Colon - Colon enteroendocrine cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" WASF1 "KIAA0269, SCAR1, WAVE, WAVE1" ENSG00000112290 "WASP family member 1" Q92558 6 110099819-110180004 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 82.8;testis: 78.6" "Cell type enhanced" "Detected in many" "Early spermatids: 175.7;Excitatory neurons: 217.1;Late spermatids: 485.7;Oligodendrocytes: 100.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 25.5;basal ganglia: 43.8;cerebral cortex: 82.8;hippocampal formation: 58.8;white matter: 36.1" "Group enriched" "Detected in some" 8 "memory B-cell: 3.3;naive B-cell: 4.2;plasmacytoid DC: 8.4" "Group enriched" "Detected in many" 9 "B-cells: 4.2;dendritic cells: 8.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004105, CAB022161" Approved Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "CAB022161: , HPA004105: AB_1080583" "unprognostic (8.22e-2)" "unprognostic (1.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.30e-3)" "unprognostic (5.50e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.82e-8)" "unprognostic (9.20e-2)" "unprognostic (5.06e-2)" "unprognostic (2.52e-1)" "unprognostic (3.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (1.95e-2)" "unprognostic (3.09e-2)" "unprognostic (9.03e-2)" "unprognostic (3.38e-1)" YWHAG "14-3-3γ, 14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.4;skeletal muscle: 349.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918" Approved Approved Approved Cytosol NA NA 66000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "CAB013274: , CAB018389: AB_2217962, HPA026918: AB_10610566" "unprognostic (3.71e-2)" "prognostic unfavorable (4.53e-4)" "unprognostic (3.88e-2)" "unprognostic (1.25e-2)" "unprognostic (6.28e-3)" "unprognostic (2.40e-3)" "unprognostic (8.98e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (1.63e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.03e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (9.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (1.70e-1)" ZNF3 "A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113" ENSG00000166526 "Zinc finger protein 3" P17036 7 100064033-100082548 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003719 Supported Supported Approved Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" Nucleoplasm "HPA003719: AB_1080701" "unprognostic (5.92e-2)" "unprognostic (3.82e-2)" "unprognostic (1.00e-1)" "unprognostic (1.01e-1)" "unprognostic (3.19e-2)" "unprognostic (2.76e-2)" "unprognostic (1.10e-1)" "prognostic favorable (5.73e-4)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.65e-1)" "unprognostic (2.50e-3)" "unprognostic (7.54e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-3)" "unprognostic (1.24e-1)" "unprognostic (3.41e-2)" "prognostic favorable (2.20e-4)"