Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 230.3;Leydig cells: 522.6;Microglial cells: 157.8;Oligodendrocytes: 383.9;Schwann cells: 231.7;Sertoli cells: 210.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 15.5" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.9;Fibroblasts: 204.1;Leydig cells: 99.8;Muller glia cells: 80.2" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.4;thyroid cancer: 48.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" AC007906.2 ENSG00000277639 "Novel protein" 16 53035690-53052873 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "choroid plexus: 86.7;fallopian tube: 77.8" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 236.7;Respiratory ciliated cells: 215.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 31.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.6;Rhabdoid: 15.6" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid - Fibroblasts" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 56: Ciliated cells - Cilium assembly" "unprognostic (1.97e-2)" "unprognostic (8.34e-3)" "unprognostic (1.63e-1)" "unprognostic (5.38e-3)" "unprognostic (1.70e-1)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (5.02e-2)" "unprognostic (6.07e-2)" "unprognostic (5.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (4.46e-3)" ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.8;Fibroblasts: 37.6;Leydig cells: 22.4;Microglial cells: 18.2;Smooth muscle cells: 20.4;Thymic epithelial cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 16.7" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Endometrial stromal cells: 45.7;Endothelial cells: 22.7;Fibroblasts: 38.1;Leydig cells: 53.3;Microglial cells: 23.7;Muller glia cells: 26.7;Peritubular cells: 41.4;Smooth muscle cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 31.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 994.8;Proximal tubular cells: 653.6" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 16.6;granulocytes: 8.1;Langerhans cells: 7.3;Leydig cells: 26.8;Peritubular cells: 15.8;Theca cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Cell type enhanced" "Detected in many" "Astrocytes: 1066.9;Excitatory neurons: 1263.4;Horizontal cells: 536.4;Inhibitory neurons: 1036.9;Oligodendrocyte precursor cells: 476.1;Oligodendrocytes: 1275.4;Rod photoreceptor cells: 487.6" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.2;Rhabdoid: 33.5" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" ARMC2 "bA787I22.1, DKFZp434P0714" ENSG00000118690 "Armadillo repeat containing 2" Q8NEN0 6 108848416-108974476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Cell type enhanced" "Detected in many" "Astrocytes: 77.5;Early spermatids: 118.1;Excitatory neurons: 84.9;Inhibitory neurons: 67.7;Late spermatids: 142.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025809, HPA053696" Enhanced Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: Myeloma - Humoral immune response" "Cluster 56: Ciliated cells - Cilium assembly" Nucleoplasm "HPA025809: AB_1845032, HPA053696: AB_2682233" "unprognostic (4.42e-2)" "unprognostic (9.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (4.00e-4)" "unprognostic (1.13e-2)" "unprognostic (3.74e-2)" "unprognostic (5.71e-2)" "unprognostic (5.19e-5)" "unprognostic (7.55e-2)" "unprognostic (1.55e-3)" "unprognostic (9.38e-2)" "unprognostic (6.44e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 30.4;Inhibitory neurons: 16.0;Oligodendrocyte precursor cells: 62.1;Oligodendrocytes: 10.5" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.2;Melanocytes: 78.4;Oligodendrocytes: 204.8;Peritubular cells: 48.3;Proximal tubular cells: 61.2;Schwann cells: 52.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.9;Fibroblasts: 68.4;Microglial cells: 23.7;Sertoli cells: 22.1;Smooth muscle cells: 63.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 343.5;Excitatory neurons: 364.6;Inhibitory neurons: 989.2;Late spermatids: 233.4;Oligodendrocyte precursor cells: 862.1;Oligodendrocytes: 213.2" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2106.8;Inhibitory neurons: 1445.3;Oligodendrocyte precursor cells: 1395.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 62.3;Kupffer cells: 49.9;Macrophages: 36.0;monocytes: 34.7;Proximal enterocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2;fallopian tube: 9.1;parathyroid gland: 7.4" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 386.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044420, HPA053065" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: AB_10963791, HPA053065: AB_2682030" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (3.07e-1)" "unprognostic (2.85e-2)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (1.74e-1)" "unprognostic (8.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.80e-4)" "unprognostic (5.21e-2)" "unprognostic (8.87e-2)" "unprognostic (2.84e-4)" "unprognostic (1.33e-1)" CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 32.1;NK-cells: 44.6;T-cells: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Skin cancer - Membrane components" "Cluster 1: T-cells - Immune response" Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 60.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 126.1;Gastric mucus-secreting cells: 72.7;Intestinal goblet cells: 103.5;Paneth cells: 69.4;Proximal enterocytes: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 84.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 589.4;Endometrial ciliated cells: 111.6;Rod photoreceptor cells: 282.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 44: Photoreceptor cells - Visual perception" "HPA044124: AB_10969197" "unprognostic (1.88e-1)" "unprognostic (2.05e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-3)" "unprognostic (2.13e-2)" "unprognostic (1.10e-1)" "unprognostic (8.63e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-2)" "unprognostic (2.23e-2)" "unprognostic (7.33e-2)" "prognostic favorable (3.42e-9)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (2.18e-2)" CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 291.3;Fibroblasts: 994.9;Late spermatids: 492.2;Thymic epithelial cells: 831.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "cervical cancer: 356.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 45.4;Glandular and luminal cells: 69.4;Melanocytes: 116.7;Smooth muscle cells: 67.9" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cancer enhanced" "Detected in many" "lung cancer: 42.6;skin cancer: 56.7" "Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Thyroid - Fibroblasts" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" CDIN1 "C15orf41, FLJ22851, HH114, MGC11326" ENSG00000186073 "CDAN1 interacting nuclease 1" Q9Y2V0 15 36579626-36810248 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 78.6;tongue: 34.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.0;Early spermatids: 142.7;Inhibitory neurons: 67.0;Late spermatids: 156.3;Oligodendrocyte precursor cells: 75.6;Oligodendrocytes: 95.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061023 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA061023: AB_2684417" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (2.93e-3)" "unprognostic (2.27e-2)" "unprognostic (2.37e-2)" "unprognostic (2.02e-2)" "unprognostic (3.40e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-6)" "unprognostic (1.22e-2)" "unprognostic (4.54e-2)" "unprognostic (1.62e-4)" "unprognostic (1.58e-1)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Cell type enhanced" "Detected in many" "Astrocytes: 48.7;Fibroblasts: 79.3;Leydig cells: 39.2;Muller glia cells: 65.6;Thymic epithelial cells: 49.3" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.7" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 38.0;Endothelial cells: 36.4;Fibroblasts: 79.9;Leydig cells: 17.9;Microglial cells: 67.5;Smooth muscle cells: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 17.3" "Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 101.5;Fibroblasts: 182.8;Schwann cells: 66.2;Smooth muscle cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Brain cancer: 29.5;colorectal cancer: 45.5;Sarcoma: 64.1;thyroid cancer: 21.1" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: NCI-H716 - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 64.5;Cardiomyocytes: 47.4;Extravillous trophoblasts: 87.4;Inhibitory neurons: 61.6;Schwann cells: 70.1;Skeletal myocytes: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 9.0;Brain cancer: 5.0;liver cancer: 5.4;prostate cancer: 10.2;Rhabdoid: 8.4;testis cancer: 11.1" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.2" "Cell type enriched" "Detected in many" 5 "Schwann cells: 192.3" "Cancer enhanced" "Detected in many" "glioma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.8" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Thyroid - Fibroblasts" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 33.5" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 26: NCI-H716 - Unknown function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" "HPA043844: AB_2732508, HPA060468: AB_2684288" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.28e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-2)" "unprognostic (5.63e-3)" "unprognostic (2.61e-2)" "unprognostic (7.58e-2)" "unprognostic (2.72e-2)" "unprognostic (7.69e-2)" "unprognostic (3.90e-3)" "unprognostic (2.33e-2)" "unprognostic (3.45e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (2.48e-3)" "unprognostic (3.09e-2)" COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 143.0;Hofbauer cells: 132.0;Microglial cells: 239.0;Syncytiotrophoblasts: 97.6" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 69.0;Inhibitory neurons: 43.3;Oligodendrocytes: 185.5;Spermatocytes: 36.3;Spermatogonia: 65.0" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" CPED1 "C7orf58, FLJ21986" ENSG00000106034 "Cadherin like and PC-esterase domain containing 1" A4D0V7 7 120988697-121297442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 78.5" "Cell type enhanced" "Detected in many" "Microglial cells: 223.5;Peritubular cells: 84.4;Skeletal myocytes: 55.4;Theca cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 10.8;intermediate monocyte: 11.3;myeloid DC: 25.2;non-classical monocyte: 7.6;plasmacytoid DC: 15.0" "Group enriched" "Detected in many" 9 "dendritic cells: 25.2;monocytes: 11.3" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012058 Uncertain Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA012058: AB_1845761" "unprognostic (7.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (4.48e-4)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.52e-3)" "prognostic favorable (3.00e-4)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (8.69e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.28e-3)" "unprognostic (5.05e-2)" "unprognostic (3.78e-1)" "unprognostic (6.54e-4)" CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Adipocytes: 31.6;Early spermatids: 65.4;Endothelial cells: 30.9;Late spermatids: 195.6;Oligodendrocytes: 33.5;Peritubular cells: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 28.0" "Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enhanced" "Detected in all" "Langerhans cells: 22509.9;Schwann cells: 11118.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.0;Club cells: 56.2;Excitatory neurons: 36.9;Inhibitory neurons: 28.6;Ionocytes: 40.4;Respiratory ciliated cells: 38.4;Salivary duct cells: 43.7" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.9;prostate cancer: 12.9" "Liver - Hepatocytes, Stomach - Chief cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 126.8;Intestinal goblet cells: 38.1;Oligodendrocyte precursor cells: 69.3;Oligodendrocytes: 39.9;Paneth cells: 35.8;Undifferentiated cells: 36.6" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 50: Enterocytes - Absorption" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 32.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 925.7;Inhibitory neurons: 562.4;Oligodendrocyte precursor cells: 243.6" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Group enriched" "Detected in many" 7 "basal ganglia: 32.3;cerebral cortex: 14.4;hippocampal formation: 9.2;hypothalamus: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "lung cancer: 1.9;Neuroblastoma: 4.1;Rhabdoid: 4.6" "Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 192.8" HPA020321 Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 889.2;Muller glia cells: 1843.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cancer enhanced" "Detected in many" "Brain cancer: 325.0" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 68: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 319.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 110.0;Cone photoreceptor cells: 106.8;Excitatory neurons: 173.6;Horizontal cells: 165.3;Inhibitory neurons: 178.2;Rod photoreceptor cells: 126.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 319.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910" Enhanced NA NA 8800 "Cluster 10: Brain - Neuronal signaling" "Cluster 68: Kidney - Mixed function" "Cluster 37: Neurons - Neuronal signaling" "CAB005920: , HPA049910: AB_2680948" "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 187.1;Excitatory neurons: 233.1;Inhibitory neurons: 253.0;Oligodendrocyte precursor cells: 170.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.4;testis cancer: 7.6" "Kidney - Proximal tubular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 118.1;Leydig cells: 44.0;Peritubular cells: 68.2;Smooth muscle cells: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 348.1;Cytotrophoblasts: 1355.8;Fibroblasts: 293.4;Syncytiotrophoblasts: 835.0;Thymic epithelial cells: 783.2" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213518-43786908 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Astrocytes: 168.0;Early spermatids: 152.0;Excitatory neurons: 445.9;Inhibitory neurons: 676.5;Late spermatids: 275.2;Oligodendrocyte precursor cells: 160.8;Oligodendrocytes: 727.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.9" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 246.4;Endometrial ciliated cells: 137.5;Glandular and luminal cells: 373.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Cancer enhanced" "Detected in some" "Bone cancer: 4.4;Leukemia: 6.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mast cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048107-137054061 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.7" "Cell type enhanced" "Detected in many" "Leydig cells: 201.3;Peritubular cells: 93.3;Proximal enterocytes: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.5" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 65: Breast cancer - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA017676: AB_1848179" "unprognostic (1.64e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (2.15e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.71e-2)" "unprognostic (4.97e-2)" "unprognostic (3.23e-1)" "unprognostic (2.99e-1)" "unprognostic (1.89e-1)" "prognostic favorable (3.51e-6)" "prognostic favorable (1.38e-4)" "unprognostic (2.51e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-3)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 99.5;Hepatocytes: 172.8;Leydig cells: 221.9;Peritubular cells: 237.0" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "liver cancer: 18.0" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Fibroblasts: 15.8;granulocytes: 4.9;Langerhans cells: 6.1;Melanocytes: 5.2;Pancreatic endocrine cells: 8.6;Peritubular cells: 4.1;Thymic epithelial cells: 5.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.6;Sarcoma: 23.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Fibroblasts: 15.9;Langerhans cells: 7.2;Leydig cells: 2.4;Peritubular cells: 4.1" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 65: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" FGF14 "FHF4, SCA27" ENSG00000102466 "Fibroblast growth factor 14" Q92915 13 101710804-102402457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Growth factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;cervix: 7.3" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1965.9;Inhibitory neurons: 2686.4;Oligodendrocyte precursor cells: 2174.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049828 Approved "Nucleoli fibrillar center" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 32: Neurons - Synaptic function" "Nucleoli fibrillar center" "HPA049828: AB_2680901" "unprognostic (2.12e-1)" "unprognostic (1.57e-1)" "unprognostic (2.83e-2)" "unprognostic (2.27e-2)" "unprognostic (8.55e-2)" "unprognostic (1.28e-1)" "unprognostic (3.33e-1)" "unprognostic (1.81e-2)" "unprognostic (2.06e-1)" "unprognostic (8.22e-2)" "unprognostic (1.22e-1)" "unprognostic (2.45e-1)" "unprognostic (7.80e-3)" "unprognostic (2.20e-3)" "unprognostic (1.65e-1)" "unprognostic (3.86e-2)" "unprognostic (8.48e-2)" FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 30.9;Excitatory neurons: 36.2;Glandular and luminal cells: 27.5;Horizontal cells: 52.6;Inhibitory neurons: 53.5;Muller glia cells: 117.6" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8" "Adipose visceral - Mesothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 270.8;Excitatory neurons: 542.5;Inhibitory neurons: 313.2;Leydig cells: 214.3;Microglial cells: 421.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 23.8" "Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 6 "Early spermatids: 47.5;Inhibitory neurons: 122.6;Late spermatids: 148.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 5.3;Rhabdoid: 5.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 32: Neurons - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 194.0;Late spermatids: 475.5;Squamous epithelial cells: 122.3;Suprabasal keratinocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 6: Late spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 91.1;Leydig cells: 239.8;Muller glia cells: 122.0;Peritubular cells: 355.1;Sertoli cells: 270.9;Theca cells: 123.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 146.2" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 19.3;Cone photoreceptor cells: 10.3;Fibroblasts: 26.1;Horizontal cells: 7.7;Rod photoreceptor cells: 27.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Bone cancer: 14.8" "Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Cardiomyocytes: 2.4;Distal tubular cells: 3.1;Excitatory neurons: 1.6;Fibroblasts: 2.2;Oligodendrocyte precursor cells: 6.7;Pancreatic endocrine cells: 1.7;Spermatogonia: 2.2;Thymic epithelial cells: 2.8" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 32.6;testis cancer: 15.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 14: Bone cancer - Transcription" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.0" "Cell type enriched" "Detected in some" 4 "Schwann cells: 119.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.9" "Region enriched" "Detected in single" 8 "cerebellum: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Neuroblastoma: 14.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" HPA020731 Approved Supported "Plasma membrane,Cytosol" NA NA 150000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" Cytosol "HPA020731: AB_1849635" "unprognostic (1.22e-1)" "unprognostic (6.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.47e-3)" "unprognostic (2.77e-3)" "unprognostic (1.27e-1)" "unprognostic (7.65e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-2)" "unprognostic (1.90e-5)" "unprognostic (2.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 19.0;Endothelial cells: 10.0;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 38.3;Fibroblasts: 9.8;Leydig cells: 25.1;Peritubular cells: 29.6;Theca cells: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.1;Extravillous trophoblasts: 70.5;Fibroblasts: 243.6;Muller glia cells: 71.1;Smooth muscle cells: 96.8;Syncytiotrophoblasts: 119.0" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in many" 5 "Gastric cancer: 93.1;liver cancer: 297.4;Rhabdoid: 106.3;testis cancer: 233.8" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 35: Liver cancer - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 246.3;Cardiomyocytes: 254.1;Fibroblasts: 248.0;Hofbauer cells: 715.1;Macrophages: 348.0;Melanocytes: 947.5" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cancer enriched" "Detected in all" 4 "skin cancer: 688.7" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Macrophages, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.5;granulocytes: 43.5;Leydig cells: 149.6;Muller glia cells: 200.3;Peritubular cells: 127.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 11 "Bone cancer: 2.9;head and neck cancer: 1.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 68: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 75.6;Distal enterocytes: 133.8;Enteroendocrine cells: 49.6;Intestinal goblet cells: 105.9;Paneth cells: 68.8;Proximal enterocytes: 125.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 38.0;testis cancer: 68.6" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 275.5;Leydig cells: 144.8;Oligodendrocytes: 390.1;Theca cells: 130.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Rhabdoid: 111.4" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 38.2;Endothelial cells: 23.3;Fibroblasts: 22.5;Microglial cells: 43.8;Salivary duct cells: 17.4;Schwann cells: 22.5" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 67.6;Brain cancer: 18.7;Rhabdoid: 20.2;skin cancer: 52.7" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 247.5;Granulosa cells: 673.5;Muller glia cells: 340.9;Thymic epithelial cells: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Group enriched" "Detected in many" 5 "Fibroblasts: 145.2;Leydig cells: 44.7;Peritubular cells: 41.0;Theca cells: 64.5" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 28.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: RS4;11 - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 188.3;Late spermatids: 42.1;Microglial cells: 60.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 13.6;Rhabdoid: 6.6" "Colon - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 62.0;Early spermatids: 19.5;Excitatory neurons: 17.3;Late spermatids: 37.4;Muller glia cells: 23.5;Oligodendrocyte precursor cells: 19.7;Skeletal myocytes: 28.7" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 15.7;Early spermatids: 15.4;Late spermatids: 22.8;Microglial cells: 14.6;Peritubular cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: DU4475 - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 194.0;Fibroblasts: 156.8;Leydig cells: 219.8;Peritubular cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.1;Fibroblasts: 73.5;Smooth muscle cells: 31.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 71.4" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.6;Gastric mucus-secreting cells: 34.0;Intestinal goblet cells: 60.9;Proximal enterocytes: 73.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 27.8" "Kidney - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.5;brain: 21.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 43.7;Oligodendrocyte precursor cells: 34.7;Oligodendrocytes: 270.2;Theca cells: 77.1" "Cancer enriched" "Detected in some" 8 "glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 17.8" "Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Microtubules "Centriolar satellite" "HPA029192: AB_10602341" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "unprognostic (5.90e-2)" "unprognostic (1.71e-2)" "unprognostic (1.89e-2)" "unprognostic (5.21e-2)" "unprognostic (2.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (2.40e-4)" "unprognostic (1.05e-1)" "unprognostic (5.87e-2)" "unprognostic (7.25e-4)" LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 398.4;Extravillous trophoblasts: 429.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 50: Enterocytes - Absorption" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 175.0;Fibroblasts: 59.0;Smooth muscle cells: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cancer enhanced" "Detected in many" "Brain cancer: 83.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 13 "Excitatory neurons: 862.2;Inhibitory neurons: 568.8;Oligodendrocyte precursor cells: 283.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.1" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.2;Granulosa cells: 67.2;Leydig cells: 110.8;Peritubular cells: 34.5;Sertoli cells: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cancer enhanced" "Detected in many" "Brain cancer: 57.1;Sarcoma: 73.1" "Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Group enriched" "Detected in many" 10 "Endometrial stromal cells: 990.9;Fibroblasts: 1398.8;Leydig cells: 414.2;Smooth muscle cells: 491.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 221.2" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.0;Oligodendrocytes: 411.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced NA NA 13000000 "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA016738: AB_1853571, HPA016739: AB_1853570" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (2.55e-2)" "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (8.53e-2)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.93e-2)" "unprognostic (5.40e-2)" "unprognostic (2.22e-3)" "unprognostic (5.83e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (3.99e-3)" MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.9;placenta: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 83.0;Endothelial cells: 34.2;Fibroblasts: 18.3;Leydig cells: 41.3;Peritubular cells: 24.3;Smooth muscle cells: 24.5;Thymic epithelial cells: 26.2" "Cancer enriched" "Detected in many" 8 "glioma: 15.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "Rhabdoid: 80.1" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 3.5;spinal cord: 9.5" HPA053793 Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 66: Endothelial cells - Angiogenesis" "HPA053793: AB_2682264" "unprognostic (1.10e-1)" "unprognostic (4.72e-2)" "unprognostic (9.82e-3)" "unprognostic (4.22e-2)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-3)" "unprognostic (4.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-5)" "unprognostic (3.67e-3)" "unprognostic (1.13e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-4)" MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 126.3;Granulosa cells: 111.5;Horizontal cells: 116.6;Muller glia cells: 454.9;Theca cells: 338.7" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 45.2" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 68: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 59.8;Fibroblasts: 123.2;Late spermatids: 91.7;Leydig cells: 73.3;Peritubular cells: 96.6;Theca cells: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 100.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.1;Excitatory neurons: 218.1;Inhibitory neurons: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 165.0" "Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 49: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.9;testis: 13.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 107.7;Inhibitory neurons: 107.6;Oligodendrocyte precursor cells: 147.3;Oligodendrocytes: 79.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.1" "Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 6: BEWO - Unknown function" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 301.8;Inhibitory neurons: 131.6;Microglial cells: 151.4;Oligodendrocyte precursor cells: 448.1;Oligodendrocytes: 503.0" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 854.7;Excitatory neurons: 1451.5;Inhibitory neurons: 738.0;Microglial cells: 519.9;Oligodendrocyte precursor cells: 752.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.6" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Astrocytes: 463.7;Oligodendrocyte precursor cells: 741.8;Oligodendrocytes: 2036.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.3" "Adipose subcutaneous - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 47: Retina - Visual perception" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 244.9;Peritubular cells: 206.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cancer enhanced" "Detected in many" "testis cancer: 57.4" "Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Cell type enhanced" "Detected in some" "NK-cells: 32.6;Peritubular cells: 7.7;Rod photoreceptor cells: 17.8;T-cells: 6.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Group enriched" "Detected in many" 7 "gdT-cell: 18.1;MAIT T-cell: 4.6;memory CD8 T-cell: 8.8;naive CD8 T-cell: 5.2;NK-cell: 10.9" "Group enriched" "Detected in many" 19 "NK-cells: 10.9;T-cells: 18.1" "Cancer enhanced" "Detected in single" "Leukemia: 1.9" "Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 956.7;Excitatory neurons: 405.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 40: Non-specific - Enzymes" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 3899.8;Excitatory neurons: 3156.4;Inhibitory neurons: 2058.1;Oligodendrocyte precursor cells: 4690.3" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "lung cancer: 4.1;Neuroblastoma: 4.1;thyroid cancer: 4.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" NRXN3 "C14orf60, KIAA0743" ENSG00000021645 "Neurexin 3" "Q9HDB5, Q9Y4C0" 14 78170373-79868291 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.8;retina: 42.9" "Group enriched" "Detected in many" 11 "Excitatory neurons: 3479.1;Inhibitory neurons: 4960.5;Oligodendrocytes: 2024.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 106.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002727 Approved NA NA 710000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "HPA002727: AB_1079468" "unprognostic (7.96e-2)" "unprognostic (5.70e-4)" "unprognostic (8.18e-3)" "unprognostic (2.19e-2)" "unprognostic (2.31e-4)" "unprognostic (9.56e-2)" "unprognostic (2.80e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-2)" "unprognostic (7.91e-2)" "unprognostic (2.40e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.83e-7)" "unprognostic (4.81e-2)" "unprognostic (2.61e-1)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 108.3;Hepatocytes: 197.7;Muller glia cells: 269.0;Theca cells: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 108.9;Fibroblasts: 181.8;Leydig cells: 166.5;Peritubular cells: 203.7;Thymic epithelial cells: 677.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 21.3" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 143.5;Hofbauer cells: 36.6;Macrophages: 28.0;Peritubular cells: 28.4;Smooth muscle cells: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 78.3;Sarcoma: 42.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 508.7;Fibroblasts: 353.8;Leydig cells: 145.9;Smooth muscle cells: 366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 216.0;Neuroblastoma: 221.5;Sarcoma: 153.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.0;Fibroblasts: 166.2;Leydig cells: 70.5;Peritubular cells: 69.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 25.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Group enriched" "Detected in many" 5 "Fibroblasts: 173.6;Leydig cells: 203.7;Oligodendrocytes: 63.6;Peritubular cells: 144.5" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cancer enriched" "Detected in some" 8 "Kidney cancer: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 208.9;Hofbauer cells: 135.1;Kupffer cells: 216.3;Macrophages: 123.9;Paneth cells: 116.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Thyroid - Fibroblasts" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.7;brain: 41.6" "Cell type enhanced" "Detected in some" "Adipocytes: 8.8;Bipolar cells: 11.1;Cone photoreceptor cells: 6.9;Horizontal cells: 23.7;Muller glia cells: 6.7;Peritubular cells: 8.9;Theca cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "HPA054810: AB_2682609" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-1)" "unprognostic (4.15e-1)" "unprognostic (4.19e-3)" "unprognostic (4.26e-4)" "unprognostic (7.30e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.32e-2)" PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 12.1;Bipolar cells: 34.2;Leydig cells: 17.9;Paneth cells: 13.5;Peritubular cells: 37.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.5" "Testis - Peritubular cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 35: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 754.1;Excitatory neurons: 241.3;Inhibitory neurons: 464.3;Microglial cells: 183.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 9.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 271.2;Endometrial stromal cells: 161.2;Fibroblasts: 216.2;Late spermatids: 410.5;Leydig cells: 267.6;Oligodendrocyte precursor cells: 276.3;Smooth muscle cells: 183.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 44.8;Rhabdoid: 66.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 131.9;Oligodendrocyte precursor cells: 106.9;Oligodendrocytes: 139.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 96.1" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.3;Inhibitory neurons: 69.6;Oligodendrocyte precursor cells: 77.0;Oligodendrocytes: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;choroid plexus: 77.8;retina: 61.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.7;Cone photoreceptor cells: 155.1;Excitatory neurons: 50.4;Horizontal cells: 62.2;Inhibitory neurons: 45.1;Rod photoreceptor cells: 60.2" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 35.2" "Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 305.1;Inhibitory neurons: 1478.5;Oligodendrocyte precursor cells: 333.6;Oligodendrocytes: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 18: Non-specific - RNA binding" "Cluster 50: Enterocytes - Absorption" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 87.9;Melanocytes: 43.5" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 30.2" "Colon - Enteric glia cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 2329.5;Hofbauer cells: 3371.1;Kupffer cells: 3606.6;Langerhans cells: 6658.3;Macrophages: 2836.0;monocytes: 4807.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 2132.7" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" SCN4B LQT10 ENSG00000177098 "Sodium voltage-gated channel beta subunit 4" Q8IWT1 11 118133377-118152888 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 109.6;tongue: 56.8" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Excitatory neurons: 18.0;Inhibitory neurons: 8.1;Late spermatids: 8.9;Sertoli cells: 19.3;Smooth muscle cells: 25.1" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatic stellate cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 11 "basal ganglia: 816.3" "Region enriched" "Detected in many" 4 "basal ganglia: 134.6" HPA017293 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 72: Smooth muscle cells - ECM organization" "HPA017293: AB_2184174" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.07e-1)" "unprognostic (9.82e-3)" "unprognostic (9.17e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.31e-4)" SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 167.6;Excitatory neurons: 174.3;Inhibitory neurons: 224.1;Muller glia cells: 73.2;Oligodendrocytes: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "thyroid cancer: 71.2" "Heart muscle - Smooth muscle cells, Kidney - Proximal tubular cells, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 2: DU4475 - Unknown function" "Cluster 35: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 7 "Fibroblasts: 712.4" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.9;Brain cancer: 15.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "brain: 405.4;retina: 315.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 358.5;Cone photoreceptor cells: 489.4;Excitatory neurons: 106.3;Rod photoreceptor cells: 397.2" "Cancer enriched" "Detected in some" 6 "glioma: 7.5" "Group enriched" "Detected in many" 7 "amygdala: 176.7;basal ganglia: 243.4;cerebral cortex: 289.7;hippocampal formation: 405.4;white matter: 169.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 15.4" "Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 201.2;cerebellum: 204.6;cerebral cortex: 339.5;hippocampal formation: 471.2" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "CAB037183: AB_261840, HPA050458: AB_2681134, HPA063679: AB_2685086" "unprognostic (1.79e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (9.12e-2)" "unprognostic (3.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.32e-2)" "unprognostic (6.61e-2)" "unprognostic (4.26e-12)" "unprognostic (8.36e-4)" "unprognostic (4.27e-1)" "unprognostic (1.35e-2)" "unprognostic (6.17e-3)" SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 138.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.5;Bipolar cells: 39.2;Club cells: 33.3;Ionocytes: 31.0;Mucus glandular cells: 49.3;Respiratory ciliated cells: 18.1;Salivary duct cells: 41.5;Schwann cells: 21.3" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 41.3" "Lung - Respiratory ciliated cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.8;Fibroblasts: 26.6;Leydig cells: 18.6;Peritubular cells: 15.4;Schwann cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 11.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Fibroblasts: 138.9;Leydig cells: 188.9;Peritubular cells: 269.9;Skeletal myocytes: 172.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Granulosa cells: 272.5;Syncytiotrophoblasts: 1045.3" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 111.9;neutrophil: 71.8;plasmacytoid DC: 93.7" "Group enriched" "Detected in many" 12 "dendritic cells: 93.7;granulocytes: 111.9" "Cancer enriched" "Detected in all" 4 "skin cancer: 240.8" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" NA NA 15000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 17: Granulosa cells - Transcription regulation" "HPA049827: AB_2680900" "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 39.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.3;Hofbauer cells: 18.6;Langerhans cells: 9.8;Macrophages: 14.5;Microglial cells: 8.2;Proximal tubular cells: 35.3;Smooth muscle cells: 8.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.3;Rhabdoid: 13.7" "Breast - Endothelial cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022745 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 60: Proximal tubular cells - Absorption" "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 40.0;Fibroblasts: 43.4;Horizontal cells: 39.1;Leydig cells: 43.0;Muller glia cells: 79.0;Oligodendrocytes: 43.8;Peritubular cells: 39.0;Sertoli cells: 52.5" "Cancer enriched" "Detected in many" 10 "glioma: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 18.5;Neuroblastoma: 56.8;Sarcoma: 17.5" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "HPA051507: AB_2681512, HPA065080: AB_2685419" "unprognostic (1.09e-2)" "unprognostic (4.36e-2)" "unprognostic (5.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (4.52e-2)" "unprognostic (2.17e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.18e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.62e-1)" "unprognostic (2.28e-2)" "unprognostic (1.35e-3)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 445.3;Late spermatids: 482.9;Leydig cells: 362.3;Melanocytes: 360.5;Peritubular cells: 748.7;Theca cells: 461.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 12: Non-specific - Chromatin organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 103.5;granulocytes: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 19: Macrophages - Innate immune response" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" ZNF704 "FLJ16218, Gig1" ENSG00000164684 "Zinc finger protein 704" Q6ZNC4 8 80628451-80874781 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 166.6;Oligodendrocyte precursor cells: 286.9;Oligodendrocytes: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 50.1" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024285, HPA024302" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA024285: AB_2219847, HPA024302: AB_1859427" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.27e-1)" "unprognostic (3.39e-3)" "unprognostic (6.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (1.26e-1)" "prognostic favorable (4.02e-4)" "unprognostic (1.68e-2)" "unprognostic (1.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.90e-2)"