Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 61: Liver - Metabolism" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.8;Fibroblasts: 37.6;Leydig cells: 22.4;Microglial cells: 18.2;Smooth muscle cells: 20.4;Thymic epithelial cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 16.7" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 32.7;Excitatory neurons: 49.5;Leydig cells: 24.1;Rod photoreceptor cells: 29.1;Thymic epithelial cells: 15.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.7" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396138-7830081 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 50.8;skeletal muscle: 68.3;tongue: 30.8" "Cell type enhanced" "Detected in many" "Astrocytes: 626.9;Excitatory neurons: 400.0;Inhibitory neurons: 413.6;Oligodendrocyte precursor cells: 173.8;Skeletal myocytes: 110.9" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.0;testis cancer: 3.8" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 348.1;Rod photoreceptor cells: 620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 435.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Endometrial stromal cells: 45.7;Endothelial cells: 22.7;Fibroblasts: 38.1;Leydig cells: 53.3;Microglial cells: 23.7;Muller glia cells: 26.7;Peritubular cells: 41.4;Smooth muscle cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 31.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 667.2;Leydig cells: 411.1;Proximal tubular cells: 388.8;Respiratory ciliated cells: 489.4" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cancer enhanced" "Detected in many" "liver cancer: 1072.2;Rhabdoid: 926.6;Sarcoma: 887.0" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 69: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" ARPIN "C15orf38, MGC61550" ENSG00000242498 "Actin related protein 2/3 complex inhibitor" Q7Z6K5 15 89895006-89912952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 98.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 5.3;intermediate monocyte: 2.9;myeloid DC: 4.5" "Group enriched" "Detected in many" 6 "dendritic cells: 4.5;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "HPA040513, HPA047173, HPA052278" Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 45: Non-specific - Cell proliferation" "Cluster 51: Late spermatids - Spermatogenesis" "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA052278: AB_2681783" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.01e-2)" "unprognostic (2.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (2.67e-3)" "unprognostic (1.75e-2)" "unprognostic (1.57e-1)" "prognostic favorable (4.19e-4)" "unprognostic (8.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (6.62e-3)" B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 118.9;Horizontal cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 35: Liver cancer - Metabolism" "Cluster 9: Neurons - Nervous system development" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 116.7;Cholangiocytes: 165.5;Distal tubular cells: 139.9;Ductal cells: 95.6;Microglial cells: 161.5;Proximal tubular cells: 177.8" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 65.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Cytotrophoblasts: 29.8;Fibroblasts: 45.0;Syncytiotrophoblasts: 40.1" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 267.9;Gastric cancer: 194.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" C12orf43 "Custos, FLJ12448" ENSG00000157895 "Chromosome 12 open reading frame 43" Q96C57 12 121000486-121016502 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046148, HPA061739" Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 30: Non-specific - Translation" "Cluster 65: Brain - Ion transport" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" Nucleoli "Golgi apparatus" "HPA046148: AB_10965169, HPA061739: AB_2684597" "unprognostic (1.51e-1)" "unprognostic (5.75e-2)" "unprognostic (3.44e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (6.44e-4)" "unprognostic (3.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.95e-1)" "unprognostic (2.45e-3)" "unprognostic (9.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.8;Alveolar cells type 2: 40.2;Basal prostatic cells: 57.3;Bipolar cells: 48.3;Endometrial ciliated cells: 61.7;Horizontal cells: 43.6" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 63.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 70: Basal prostatic cells - Lipid metabolism" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 454.0;Fibroblasts: 688.8;Hepatocytes: 1166.1;Leydig cells: 1154.2;Peritubular cells: 402.2;Thymic epithelial cells: 590.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 79.0" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 258.8;Late spermatids: 732.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: Non-specific - Protein binding" "Cluster 51: Late spermatids - Spermatogenesis" "HPA012548: AB_1845748" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.77e-5)" "unprognostic (3.75e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-3)" "unprognostic (8.42e-3)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.3;Excitatory neurons: 35.0;Horizontal cells: 56.4;Inhibitory neurons: 39.5;Melanocytes: 64.4;Muller glia cells: 32.5;Schwann cells: 89.8" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 54.1;skin cancer: 22.2" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.5;Fibroblasts: 37.8;Hofbauer cells: 49.1;Leydig cells: 45.8;monocytes: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.3;Hofbauer cells: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 54: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 301.7;Endothelial cells: 261.2;Fibroblasts: 116.9;Leydig cells: 144.5;Peritubular cells: 120.1;Thymic epithelial cells: 170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Leukemia: 59.0;Rhabdoid: 112.2;Sarcoma: 91.0" "Breast - Fibroblasts, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.4;Inhibitory neurons: 48.5;Muller glia cells: 34.4;Thymic epithelial cells: 50.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 23.8" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 65: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 28.8;Excitatory neurons: 27.8;Fibroblasts: 15.6;Hepatocytes: 25.4;Horizontal cells: 15.4;Inhibitory neurons: 36.8;Smooth muscle cells: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 41.2;Fibroblasts: 163.9;Leydig cells: 226.7;Peritubular cells: 56.4;Skeletal myocytes: 74.2;Theca cells: 79.2" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ovarian cancer: 3.8;Uterine cancer: 3.9" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 103.1;Extravillous trophoblasts: 263.3;Granulosa cells: 133.7;Hofbauer cells: 121.7;Sertoli cells: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 17: RS4;11 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 101.5;Fibroblasts: 182.8;Schwann cells: 66.2;Smooth muscle cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Brain cancer: 29.5;colorectal cancer: 45.5;Sarcoma: 64.1;thyroid cancer: 21.1" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: NCI-H716 - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 129.4;Fibroblasts: 126.5;Leydig cells: 61.6;Pancreatic endocrine cells: 61.8;Schwann cells: 50.9;Smooth muscle cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 233.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 538.6;Fibroblasts: 757.2;Leydig cells: 347.8;Peritubular cells: 238.2;Smooth muscle cells: 353.7;Theca cells: 318.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 487.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 143.0;Hofbauer cells: 132.0;Microglial cells: 239.0;Syncytiotrophoblasts: 97.6" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 96 "granulocytes: 2694.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cancer enriched" "Detected in some" 11 "Leukemia: 14.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Lung - Mast cells, Skeletal muscle - Macrophages" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 46: Granulocytes - Mast cell degranulation" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Hypogonadotropic hypogonadism, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 704.7;Bipolar cells: 616.6;Cone photoreceptor cells: 1283.9;Leydig cells: 497.8;Muller glia cells: 521.8;Peritubular cells: 616.4;Prostatic glandular cells: 924.9;Rod photoreceptor cells: 746.0;Sertoli cells: 514.1" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 342.6;thyroid cancer: 385.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 44: Photoreceptor cells - Visual perception" "Vesicles, Centrosome" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 69.0;Inhibitory neurons: 43.3;Oligodendrocytes: 185.5;Spermatocytes: 36.3;Spermatogonia: 65.0" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 61: Non-specific - Transcription" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 367.5;granulocytes: 292.0;Late spermatids: 168.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Supported Nucleoplasm,Centrosome,Cytosol No No "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 17: RS4;11 - Unknown function" "Cluster 46: Granulocytes - Mast cell degranulation" Nucleoplasm "Centrosome, Cytosol" "HPA004742: AB_1847323, HPA027906: , HPA027907: AB_10601362" "unprognostic (2.81e-1)" "unprognostic (3.42e-1)" "unprognostic (8.80e-2)" "unprognostic (1.88e-3)" "unprognostic (1.93e-1)" "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (5.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (5.31e-2)" DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 82.1;Exocrine glandular cells: 71.6;Fibroblasts: 70.5;Pancreatic endocrine cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 198.8;Oligodendrocyte precursor cells: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 366.4;Late spermatids: 777.3;Spermatocytes: 190.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 22.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 106.0;Leydig cells: 95.6;Muller glia cells: 83.7;Peritubular cells: 102.7;Smooth muscle cells: 99.7;Theca cells: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" EID2B "EID-3, FLJ38944" ENSG00000176401 "EP300 interacting inhibitor of differentiation 2B" Q96D98 19 39530987-39532852 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.9;Cone photoreceptor cells: 39.6;Horizontal cells: 28.2;Rod photoreceptor cells: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" HPA064185 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "HPA064185: AB_2685207" "unprognostic (1.15e-1)" "unprognostic (8.53e-3)" "unprognostic (6.41e-3)" "unprognostic (1.08e-3)" "unprognostic (4.00e-1)" "unprognostic (7.08e-2)" "unprognostic (9.92e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.57e-4)" "unprognostic (6.80e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-2)" "unprognostic (1.78e-1)" "unprognostic (2.77e-1)" "unprognostic (4.20e-2)" FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.5;Endothelial cells: 30.5;Fibroblasts: 25.2;Inhibitory neurons: 33.9;Microglial cells: 22.8;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 19.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.2;Extravillous trophoblasts: 11.7;Fibroblasts: 14.1;Inhibitory neurons: 30.1;Melanocytes: 22.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 945.8;Inhibitory neurons: 286.5;Oligodendrocyte precursor cells: 321.5;Oligodendrocytes: 723.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Vascular Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 32: Neurons - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 179.2;Leydig cells: 196.8;Oligodendrocyte precursor cells: 159.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 202.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 77.2;Fibroblasts: 97.2;Leydig cells: 47.1;Smooth muscle cells: 51.6;Theca cells: 75.4;Thymic epithelial cells: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013808, HPA051171, HPA057021" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA013808: , HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 133.2;Endometrial stromal cells: 56.9;Fibroblasts: 58.1;Late spermatids: 49.8;Leydig cells: 66.1;Peritubular cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 3183.4;Fibroblasts: 713.4;Hepatocytes: 809.9;Pancreatic endocrine cells: 523.8;Smooth muscle cells: 552.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 4649.5;thyroid cancer: 4327.2" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 227000000000000 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 133.5;Late spermatids: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" NA NA 53000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 46: Granulocytes - Mast cell degranulation" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Cell type enhanced" "Detected in some" "Early spermatids: 34.0;Intestinal goblet cells: 33.4;Late spermatids: 100.8;Oligodendrocyte precursor cells: 14.4" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Breast - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 51: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cancer enhanced" "Detected in all" "Bile duct cancer: 253.2" "Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Cardiomyocytes: 2.4;Distal tubular cells: 3.1;Excitatory neurons: 1.6;Fibroblasts: 2.2;Oligodendrocyte precursor cells: 6.7;Pancreatic endocrine cells: 1.7;Spermatogonia: 2.2;Thymic epithelial cells: 2.8" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 32.6;testis cancer: 15.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 14: Bone cancer - Transcription" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: BEWO - Unknown function" "Cluster 19: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 36: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 179.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Lung - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 69: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 285.0;Hepatocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 1: T-cells - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1364113 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 560000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 8: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9;tongue: 54.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 108.6;Oligodendrocyte precursor cells: 129.0;Oligodendrocytes: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.2;T-reg: 1.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.2;T-cells: 1.8" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 461.9;Inhibitory neurons: 387.3;Oligodendrocyte precursor cells: 368.7" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;liver cancer: 6.3;thyroid cancer: 5.1" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" GRID1 "GluD1, KIAA1220" ENSG00000182771 "Glutamate ionotropic receptor delta type subunit 1" Q9ULK0 10 85599552-86366795 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.4" "Group enriched" "Detected in some" 19 "Astrocytes: 145.2;Excitatory neurons: 280.5;Inhibitory neurons: 294.7;Oligodendrocyte precursor cells: 302.8;Oligodendrocytes: 504.2" "Group enriched" "Detected in many" 5 "glioma: 3.6;thyroid cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.3" "Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" "unprognostic (7.60e-2)" "unprognostic (2.75e-2)" "unprognostic (5.92e-2)" "unprognostic (4.31e-2)" "unprognostic (4.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.21e-2)" "unprognostic (5.09e-2)" "unprognostic (1.49e-3)" "unprognostic (8.30e-2)" "unprognostic (8.26e-2)" "unprognostic (4.58e-9)" "unprognostic (3.15e-3)" "unprognostic (5.91e-2)" "unprognostic (2.21e-1)" "unprognostic (8.65e-3)" HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Cell type enhanced" "Detected in many" "Astrocytes: 60.1;Excitatory neurons: 116.2;Inhibitory neurons: 83.0;Late spermatids: 72.9;Oligodendrocyte precursor cells: 81.8;Oligodendrocytes: 117.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 119.6;Excitatory neurons: 525.8;Inhibitory neurons: 154.0;Late spermatids: 79.4;Oligodendrocyte precursor cells: 266.2" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "cerebral cortex: 16.4" "Group enriched" "Detected in some" 4 "basophil: 4.9;neutrophil: 3.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.9" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "Nucleoli fibrillar center, Cytosol" "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 38.2;Endothelial cells: 23.3;Fibroblasts: 22.5;Microglial cells: 43.8;Salivary duct cells: 17.4;Schwann cells: 22.5" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 67.6;Brain cancer: 18.7;Rhabdoid: 20.2;skin cancer: 52.7" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 10.8;Endometrial ciliated cells: 10.5;Granulosa cells: 10.7;Squamous epithelial cells: 7.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "medulla oblongata: 16.7;pons: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_2" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 49 "medulla oblongata: 4.9;pons: 3.7;spinal cord: 6.0" HPA053910 Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 56: Neurons - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 12 "Hepatocytes: 1601.8;Proximal tubular cells: 1497.2" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cancer enhanced" "Detected in many" "liver cancer: 45.8;Rhabdoid: 38.6" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" IFFO1 "HOM-TES-103, IFFO" ENSG00000010295 "Intermediate filament family orphan 1" Q0D2I5 12 6538961-6556073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069344 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "HPA069344: AB_2686126" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (4.38e-2)" "unprognostic (3.33e-3)" "unprognostic (2.69e-2)" "unprognostic (1.43e-3)" "unprognostic (4.37e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (5.25e-2)" "prognostic favorable (6.53e-5)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.47e-7)" "unprognostic (5.71e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (5.58e-2)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 194.0;Fibroblasts: 156.8;Leydig cells: 219.8;Peritubular cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 25.5;skeletal muscle: 69.1;tongue: 25.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.4;Horizontal cells: 30.8;Muller glia cells: 9.3;Skeletal myocytes: 19.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Skeletal muscle - Skeletal myocytes" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 9: Neurons - Nervous system development" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 128.1;Excitatory neurons: 137.6;Oligodendrocytes: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 38: Neurons - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 414.0;Inhibitory neurons: 345.8;Oligodendrocyte precursor cells: 249.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;fallopian tube: 16.8;placenta: 19.0;skeletal muscle: 22.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 52.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 75.0;Oligodendrocyte precursor cells: 43.3;Oligodendrocytes: 99.1;Syncytiotrophoblasts: 25.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.4" "Breast - Fibroblasts" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 591.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 727.9;monocytes: 143.5;Oligodendrocyte precursor cells: 246.0;Skeletal myocytes: 250.4" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.2;skin cancer: 3.2" "Breast - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 41: Alveolar cells - Lung function" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.6;Leydig cells: 975.0;Peritubular cells: 618.8;Schwann cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 53.7" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 49: Non-specific - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 27.2;Cardiomyocytes: 29.4;Cholangiocytes: 26.9;Endometrial stromal cells: 30.1;Fibroblasts: 17.1;Hepatocytes: 58.1" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.0;Rhabdoid: 14.0" "Breast - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 238.8;Fibroblasts: 59.2;Granulosa cells: 89.6;Leydig cells: 55.4;Peritubular cells: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 118.5;Extravillous trophoblasts: 262.6;Pancreatic endocrine cells: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 10.5;Fibroblasts: 17.9;Leydig cells: 12.7;NK-cells: 10.6;Peritubular cells: 22.3;Thymic epithelial cells: 41.3" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.6;Leydig cells: 413.2;Paneth cells: 236.9;Peritubular cells: 381.9;Proximal enterocytes: 413.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 65: Fibroblasts - ECM organization" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 17: Granulosa cells - Transcription regulation" "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 56.9;Endometrial stromal cells: 26.7;Fibroblasts: 22.3;Smooth muscle cells: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.6" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2410.7;Hofbauer cells: 3070.5" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 46: Non-specific - Unknown function" "Cluster 69: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 63.2;Oligodendrocyte precursor cells: 58.7;Paneth cells: 57.7;Rod photoreceptor cells: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 22.8;Club cells: 23.7;Ionocytes: 34.4;Oligodendrocyte precursor cells: 131.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 108.3;Hepatocytes: 197.7;Muller glia cells: 269.0;Theca cells: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 14.1;Fibroblasts: 46.2;Leydig cells: 42.3;Peritubular cells: 39.0;Smooth muscle cells: 18.9;Thymic epithelial cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 116.1;Endometrial stromal cells: 34.8;Leydig cells: 35.4;Peritubular cells: 45.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048682 Uncertain "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA048682: AB_2680492" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 68.2;Fibroblasts: 53.1;Leydig cells: 39.2;Peritubular cells: 57.2;Smooth muscle cells: 30.7;Theca cells: 19.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6;testis cancer: 38.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.3;Endometrial stromal cells: 3.3;Fibroblasts: 4.0;Leydig cells: 2.4;Peritubular cells: 2.8;Sertoli cells: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 1.9;Bipolar cells: 4.3;Endometrial stromal cells: 2.6;Fibroblasts: 2.4;Melanocytes: 1.7;Mucus glandular cells: 1.8;Peritubular cells: 2.0;Skeletal myocytes: 2.0;Smooth muscle cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.1" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Testis - Early spermatids" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.3;Bipolar cells: 7.6;Fibroblasts: 11.8;Serous glandular cells: 8.6;Skeletal myocytes: 7.9;Thymic epithelial cells: 11.0" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.9;Fibroblasts: 7.3;granulocytes: 12.6;Langerhans cells: 14.1;Leydig cells: 6.9;Microglial cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 374.7;Fibroblasts: 250.2;Leydig cells: 430.4;Oligodendrocyte precursor cells: 478.5;Peritubular cells: 384.7" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 76.7;thyroid cancer: 37.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Basal respiratory cells: 93.9;Muller glia cells: 80.7;Peritubular cells: 65.7;Thymic epithelial cells: 324.9" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 119.0;thyroid cancer: 95.0" "Breast - Fibroblasts, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 130.8;Inhibitory neurons: 138.3;Langerhans cells: 264.8;Microglial cells: 175.1;Oligodendrocyte precursor cells: 520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in some" 6 "Oligodendrocytes: 377.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 711.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 631.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1727.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1727.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Colon - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1468.6;Oligodendrocytes: 443.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 20.9" "Lineage enriched" "Detected in all" 5 "monocytes: 20.9" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" NA NA 60000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 26: Intestinal epithelial cells - Absorption" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 14.6;Endometrial stromal cells: 6.0;Excitatory neurons: 7.8;Fibroblasts: 8.6;Inhibitory neurons: 6.3;Oligodendrocytes: 10.3;Smooth muscle cells: 7.5;Theca cells: 8.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.1;seminal vesicle: 27.2" "Cell type enriched" "Detected in many" 5 "Bipolar cells: 240.9" "Cancer enhanced" "Detected in many" "prostate cancer: 4.6" "Region enhanced" "Detected in many" "cerebral cortex: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 24: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 35: Bipolar cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA057253: AB_2683382" "unprognostic (2.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.65e-1)" "unprognostic (7.95e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.89e-11)" "unprognostic (4.64e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-1)" PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 264.5;Thymic epithelial cells: 87.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 29: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 3013.6;Kupffer cells: 1947.7;Macrophages: 1803.4;monocytes: 2022.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 69: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 4511.3;Inhibitory neurons: 1126.6;Oligodendrocyte precursor cells: 1120.6;Oligodendrocytes: 2974.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "bone marrow: 58.9" "Cell type enriched" "Detected in some" 10 "granulocytes: 25.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cancer enriched" "Detected in single" 104 "Leukemia: 26.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA079390 Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" Vesicles "HPA079390: " "unprognostic (8.86e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (9.56e-2)" "unprognostic (6.35e-4)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" "unprognostic (2.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.13e-3)" "unprognostic (3.03e-2)" "unprognostic (9.67e-3)" "unprognostic (5.79e-2)" RCVRN RCV1 ENSG00000109047 Recoverin P35243 17 9896320-9905271 "Plasma proteins, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 434 "retina: 463.8" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 2383.4;Rod photoreceptor cells: 1489.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Breast - Fibroblasts" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA015783, CAB022363" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "CAB022363: , HPA015783: AB_2669298" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" "unprognostic (7.95e-3)" "unprognostic (4.82e-2)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-4)" "unprognostic (1.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.41e-2)" "unprognostic (9.23e-2)" RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 129.4;Excitatory neurons: 173.7;Inhibitory neurons: 138.7;Macrophages: 81.6;Microglial cells: 74.8;Oligodendrocytes: 174.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" RTF2 "C20orf43, CDAO5, HSPC164, RTFDC1" ENSG00000022277 "Replication termination factor 2" Q9BY42 20 56468585-56519449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053986 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Nucleoli" "HPA053986: AB_2682333" "unprognostic (1.65e-1)" "unprognostic (1.94e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.54e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (8.90e-2)" "unprognostic (4.02e-3)" "unprognostic (1.16e-1)" "unprognostic (8.98e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (4.58e-1)" "unprognostic (8.48e-3)" RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.3;Excitatory neurons: 194.0;Inhibitory neurons: 317.9;Microglial cells: 100.3;Oligodendrocyte precursor cells: 251.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6;testis cancer: 7.8" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 68: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 301.5;Proximal enterocytes: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" SEC14L5 "KIAA0420, PRELID4B" ENSG00000103184 "SEC14 like lipid binding 5" O43304 16 4958330-5019157 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 78.7" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 48.3;Excitatory neurons: 66.0;Oligodendrocytes: 178.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041492, HPA041825" Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: DU4475 - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA041492: AB_10794519, HPA041825: AB_10794526" "unprognostic (1.90e-3)" "unprognostic (4.08e-2)" "unprognostic (5.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (7.33e-3)" "unprognostic (8.71e-4)" "unprognostic (6.87e-2)" "unprognostic (1.56e-4)" "unprognostic (1.01e-3)" "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 7 "Fibroblasts: 712.4" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.9;Brain cancer: 15.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 429.1;Fibroblasts: 174.7;Granulosa cells: 98.3;Peritubular cells: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 6.9;Brain cancer: 10.6;Kidney cancer: 7.8;lung cancer: 7.7;Sarcoma: 3.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 88.3;Mucus glandular cells: 44.4;Oligodendrocytes: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;skeletal muscle: 219.7" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 43.5" "Cancer enhanced" "Detected in all" "glioma: 49.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA061273: AB_2684460, HPA067885: " "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (1.48e-3)" "unprognostic (2.12e-3)" "unprognostic (6.59e-2)" "unprognostic (8.29e-3)" "unprognostic (7.06e-2)" "unprognostic (5.00e-2)" "unprognostic (2.32e-1)" "unprognostic (1.44e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 69.9;Syncytiotrophoblasts: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 48: Non-specific - RNA binding" "Cluster 4: Platelets - Platelet activation" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 186.9;Cone photoreceptor cells: 81.0;Rod photoreceptor cells: 70.1" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Group enriched" "Detected in some" 5 "Brain cancer: 4.9;breast cancer: 9.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" SLC37A3 DKFZp761N0624 ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: Non-specific - Transcription" "Cluster 52: Endometrial stromal cells - ECM organization" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 253.9;Inhibitory neurons: 534.8;Oligodendrocytes: 149.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 25.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 199.3;Fibroblasts: 112.0;Smooth muscle cells: 101.1;Thymic epithelial cells: 48.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 149.3;Muller glia cells: 183.6;Rod photoreceptor cells: 136.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: Non-specific - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 275.7;Hofbauer cells: 338.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 290.2;naive B-cell: 289.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037400, HPA077664" Approved Enhanced Endosomes,Lysosomes NA NA 150000 "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 57: Non-specific - Translation" "Cluster 12: Non-specific - Chromatin organization" Endosomes Lysosomes "HPA037400: AB_10670381, HPA077664: " "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favorable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 125.0;Oligodendrocytes: 102.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 27.5" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 41: Alveolar cells - Lung function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 11 "Oligodendrocyte precursor cells: 293.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 8.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" SUMO3 "SMT3A, SMT3H1" ENSG00000184900 "Small ubiquitin like modifier 3" P55854 21 44805617-44818779 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "CAB012180, HPA042123, HPA048064" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 23: Langerhans cells - Immune response" "Nucleoplasm, Nuclear bodies" "CAB012180: AB_304041, HPA042123: AB_2677860, HPA048064: AB_2680244" "unprognostic (2.77e-2)" "unprognostic (2.52e-1)" "unprognostic (5.79e-2)" "prognostic unfavorable (7.88e-5)" "unprognostic (1.96e-1)" "unprognostic (1.21e-1)" "unprognostic (6.81e-2)" "unprognostic (7.13e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (7.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.00e-2)" "unprognostic (1.62e-1)" "unprognostic (7.50e-2)" "unprognostic (1.80e-2)" TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 2802.0;Syncytiotrophoblasts: 989.3" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 54: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981535-34985353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 19.3;Fibroblasts: 12.6;Gastric mucus-secreting cells: 10.1;Microglial cells: 10.9;Schwann cells: 32.5;T-cells: 12.8;Thymic epithelial cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 38: Non-specific - mRNA processing" "Cluster 61: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Immunity, Innate immunity" "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 199.3;Excitatory neurons: 395.1;Inhibitory neurons: 433.7;Microglial cells: 300.1;Oligodendrocyte precursor cells: 456.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 37: Neurons - Neuronal signaling" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 325.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 27: TE 441.T - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)" VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 337.9;Hepatocytes: 776.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219, HPA064649, HPA070916" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: NCI-H716 - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB034216: AB_2234159, CAB034219: AB_2130519, HPA064649: AB_2685312, HPA070916: AB_2686322" "unprognostic (1.98e-3)" "unprognostic (3.75e-2)" "unprognostic (8.40e-2)" "unprognostic (3.89e-3)" "unprognostic (2.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (2.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.69e-2)" "unprognostic (9.10e-3)" "unprognostic (1.53e-1)" "unprognostic (9.39e-3)" "unprognostic (5.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 232.3;Schwann cells: 136.7;Squamous epithelial cells: 166.8" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 2: DU4475 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)"