Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CD22	"SIGLEC-2, SIGLEC2"	ENSG00000012124	"CD22 molecule"	P20273	19	35319261-35347361	"CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 141.3;lymphoid tissue: 230.2;ovary: 132.8"	"Group enriched"	"Detected in many"	7	"B-cells: 157.6;granulocytes: 47.4;Granulosa cells: 51.9;Oligodendrocytes: 86.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	24	"memory B-cell: 97.6;naive B-cell: 120.3"	"Lineage enriched"	"Detected in many"	26	"B-cells: 120.3"	"Cancer enriched"	"Detected in many"	4	"lymphoma: 197.3"	"Colon - Mast cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"CAB002418, HPA024353, HPA066523"	Enhanced					NA	NA		13000	"Cluster 21: B-cells - Adaptive immune response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 64: Lymphoma - Humoral immune response"	"Cluster 62: B-cells - B-cell activation"			"CAB002418: AB_563529, HPA024353: AB_10600695, HPA066523: "	"unprognostic (2.80e-3)"	"unprognostic (3.99e-2)"	"unprognostic (6.79e-3)"	"unprognostic (9.17e-2)"	"unprognostic (3.07e-1)"	"unprognostic (6.45e-3)"	"unprognostic (3.79e-1)"	"unprognostic (3.32e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.47e-1)"	"unprognostic (1.75e-3)"	"unprognostic (1.98e-2)"	"unprognostic (1.48e-2)"	"unprognostic (9.05e-2)"	"unprognostic (3.04e-1)"	"unprognostic (2.35e-2)"	"unprognostic (1.48e-1)"
HPGDS	"GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS"	ENSG00000163106	"Hematopoietic prostaglandin D synthase"	O60760	4	94298535-94342876	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism"	"Isomerase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 18.7"	"Group enriched"	"Detected in some"	30	"granulocytes: 1366.7;Hofbauer cells: 579.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	28	"basophil: 18.1"	"Lineage enriched"	"Detected in single"	28	"granulocytes: 18.1"	"Cancer enriched"	"Detected in single"	35	"Leukemia: 7.3"	"Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA024035	Enhanced		Approved	Nucleoplasm,Vesicles,Cytosol		NA	NA		250000	"Cluster 46: Basophils - DNA binding"	"Cluster 19: Lung - Lung function"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 46: Granulocytes - Mast cell degranulation"	"Vesicles, Cytosol"	Nucleoplasm	"HPA024035: AB_1855743"	"unprognostic (5.71e-2)"	"unprognostic (5.80e-3)"	"unprognostic (1.17e-1)"	"unprognostic (5.36e-3)"	"unprognostic (2.76e-1)"	"unprognostic (2.38e-4)"	"unprognostic (1.01e-2)"	"unprognostic (4.41e-3)"	"unprognostic (1.35e-1)"	"unprognostic (7.75e-4)"	"unprognostic (1.44e-1)"	"unprognostic (1.14e-1)"	"unprognostic (5.15e-3)"	"unprognostic (4.07e-2)"	"unprognostic (6.48e-2)"	"unprognostic (2.61e-2)"	"unprognostic (6.14e-2)"
IL5RA	"CD125, CDw125, IL5R"	ENSG00000091181	"Interleukin 5 receptor subunit alpha"	Q01344	3	3066324-3126613	"CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 9.0;fallopian tube: 10.7"	"Group enriched"	"Detected in some"	5	"Endometrial ciliated cells: 28.2;granulocytes: 25.9;Plasma cells: 16.1;Respiratory ciliated cells: 25.9"	"Cancer enhanced"	"Detected in some"		"prostate cancer: 1.4"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	192	"basophil: 178.4;eosinophil: 355.1"	"Lineage enriched"	"Detected in many"	255	"granulocytes: 355.1"	"Cancer enhanced"	"Detected in some"		"lymphoma: 3.4;Myeloma: 8.2"	"Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Mast cells, Testis - Early spermatids, Testis - Late spermatids"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"								"Intracellular and membrane"	NA	NA		910000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 50: L-1236 & L-428 - Unknown function"	"Cluster 56: Ciliated cells - Cilium assembly"				"unprognostic (1.38e-3)"	"unprognostic (2.26e-2)"	"unprognostic (2.66e-1)"	"unprognostic (6.13e-3)"	"unprognostic (2.66e-1)"	"unprognostic (1.54e-3)"	"unprognostic (7.79e-3)"	"unprognostic (8.42e-2)"	"unprognostic (2.83e-1)"	"unprognostic (1.67e-1)"	"unprognostic (9.84e-4)"	"unprognostic (4.32e-3)"	"unprognostic (3.08e-2)"	"unprognostic (6.95e-2)"	"unprognostic (2.20e-1)"	"unprognostic (7.49e-2)"	"unprognostic (4.93e-2)"
LAX1	"FLJ20340, LAX"	ENSG00000122188	"Lymphocyte transmembrane adaptor 1"	Q8IWV1	1	203765177-203776372	"Predicted membrane proteins"	"Adaptive immunity, Immunity"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	4	"lymphoid tissue: 21.2"	"Cell type enhanced"	"Detected in some"		"granulocytes: 176.3;NK-cells: 31.2;Plasma cells: 63.0;T-cells: 31.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	14	"B-cells: 7.5;NK-cells: 5.2;T-cells: 12.0"	"Cancer enriched"	"Detected in some"	6	"Myeloma: 38.5"	"Adipose subcutaneous - Mast cells, Breast - Plasma cells, Colon - Mast cells"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA002461, HPA003887, CAB025358"	Enhanced		Enhanced	"Golgi apparatus,Plasma membrane,Cytosol"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 46: Granulocytes - Mast cell degranulation"	"Plasma membrane, Cytosol"	"Golgi apparatus"	"CAB025358: , HPA002461: AB_1079239, HPA003887: AB_1079240"	"unprognostic (2.85e-3)"	"unprognostic (3.83e-3)"	"unprognostic (3.90e-4)"	"unprognostic (3.65e-2)"	"unprognostic (5.22e-2)"	"unprognostic (1.03e-5)"	"unprognostic (2.99e-2)"	"unprognostic (4.91e-2)"	"unprognostic (4.36e-2)"	"unprognostic (3.31e-3)"	"unprognostic (4.77e-1)"	"unprognostic (4.36e-1)"	"unprognostic (4.23e-4)"	"unprognostic (3.07e-1)"	"unprognostic (1.12e-1)"	"unprognostic (2.15e-1)"	"unprognostic (1.51e-1)"
MRGPRX2	MRGX2	ENSG00000183695	"MAS related GPR family member X2"	Q96LB1	11	19054455-19060717	"G-protein coupled receptors, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in single"		"skin 1: 1.0"	"Cell type enriched"	"Detected in some"	9	"granulocytes: 16.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Adipose subcutaneous - Mast cells, Colon - Mast cells, Skin - Mast cells"									HPA055220	Approved					NA	NA				"Cluster 31: Skin - Epidermis development"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 46: Granulocytes - Mast cell degranulation"			"HPA055220: AB_2682743"						"unprognostic (1.56e-2)"											"unprognostic (1.79e-1)"
PIK3R6	"C17orf38, FLJ34500, HsT41028, p87PIKAP"	ENSG00000276231	"Phosphoinositide-3-kinase regulatory subunit 6"	Q5UE93	17	8802722-8867677	"Metabolic proteins, Predicted intracellular proteins"	Angiogenesis			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"lymphoid tissue: 2.9"	"Cell type enhanced"	"Detected in some"		"Early spermatids: 7.6;granulocytes: 33.7;Hofbauer cells: 7.2;Late spermatids: 22.4;Microglial cells: 7.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"basophil: 21.9;eosinophil: 75.8"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 75.8"	"Group enriched"	"Detected in some"	7	"Leukemia: 6.7;lymphoma: 6.7"	"Colon - Mast cells, Testis - Late spermatids, Thyroid - T-cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA023077	Approved		Approved	"Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 46: Granulocytes - Mast cell degranulation"	"Nucleoplasm, Golgi apparatus"	"Plasma membrane, Cytosol"	"HPA023077: AB_1854909"	"unprognostic (4.29e-2)"	"unprognostic (8.56e-3)"	"unprognostic (9.39e-2)"	"unprognostic (5.96e-3)"	"unprognostic (2.46e-1)"	"unprognostic (5.25e-3)"	"unprognostic (4.50e-3)"	"unprognostic (2.29e-2)"	"unprognostic (3.12e-2)"	"unprognostic (3.14e-1)"	"unprognostic (2.20e-2)"	"unprognostic (1.38e-1)"	"prognostic unfavorable (1.50e-6)"	"unprognostic (3.45e-1)"	"unprognostic (3.91e-2)"	"unprognostic (2.68e-1)"	"unprognostic (8.98e-2)"
STAP1	"BRDG1, STAP-1"	ENSG00000035720	"Signal transducing adaptor family member 1"	Q9ULZ2	4	67558727-67607337	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"lymphoid tissue: 51.0"	"Cell type enhanced"	"Detected in some"		"B-cells: 68.2;dendritic cells: 22.6;Distal tubular cells: 28.0;granulocytes: 55.6;Plasma cells: 134.2"	"Cancer enriched"	"Detected in many"	7	"renal cancer: 13.0"	"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in many"		"memory B-cell: 88.1;naive B-cell: 107.8"	"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in some"	10	"Leukemia: 14.5;lymphoma: 55.0"	"Colon - Mast cells, Kidney - Intercalated cells, Testis - Early spermatids"	"Region enriched"	"Detected in single"	5	"cerebellum: 2.3"	"Low region specificity"	"Detected in all"			"HPA038529, HPA058018"	Enhanced		Supported	"Nucleoplasm,Centriolar satellite,Mitochondria,Cytosol"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 64: Lymphoma - Humoral immune response"	"Cluster 62: B-cells - B-cell activation"	"Nucleoplasm, Centriolar satellite, Mitochondria"	Cytosol	"HPA038529: AB_10673011, HPA058018: "	"unprognostic (1.14e-4)"	"unprognostic (1.49e-3)"	"unprognostic (2.30e-2)"	"unprognostic (2.17e-1)"	"unprognostic (1.63e-3)"	"unprognostic (6.30e-4)"	"unprognostic (1.95e-3)"	"unprognostic (6.95e-3)"	"unprognostic (5.18e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.47e-1)"	"unprognostic (8.43e-3)"	"unprognostic (3.11e-2)"	"unprognostic (1.49e-2)"	"unprognostic (4.69e-2)"	"unprognostic (2.71e-2)"	"unprognostic (1.40e-1)"
TESPA1	"ITPRID3, KIAA0748"	ENSG00000135426	"Thymocyte expressed, positive selection associated 1"	A2RU30	12	54948015-54984762	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"brain: 81.3;lymphoid tissue: 75.2"	"Cell type enhanced"	"Detected in some"		"Erythroid cells: 32.3;Excitatory neurons: 200.1;granulocytes: 88.4;T-cells: 39.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in some"	9	"Leukemia: 42.7;lymphoma: 24.5"	"Adipose visceral - T-cells, Colon - Mast cells, Kidney - T-cells, Skeletal muscle - Fibroblasts, Thyroid - T-cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA058823, HPA079222"	Approved		Supported	Cytosol		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 38: Neurons - Neuronal signaling"	Cytosol		"HPA058823: AB_2683828, HPA079222: "	"unprognostic (1.98e-5)"	"unprognostic (3.70e-4)"	"unprognostic (3.87e-4)"	"unprognostic (1.13e-3)"	"unprognostic (3.20e-2)"	"unprognostic (4.55e-4)"	"unprognostic (2.29e-3)"	"unprognostic (5.34e-4)"	"unprognostic (3.83e-4)"	"unprognostic (1.35e-2)"	"unprognostic (3.97e-2)"	"unprognostic (5.89e-2)"	"unprognostic (4.50e-2)"	"unprognostic (4.11e-1)"	"unprognostic (1.28e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.71e-1)"