Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
GZMH	"CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2"	ENSG00000100450	"Granzyme H"	P20718	14	24606480-24609699	"Enzymes, Predicted secreted proteins"	Cytolysis	"Hydrolase, Protease, Serine protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 33.9;lymphoid tissue: 25.2"	"Group enriched"	"Detected in some"	19	"NK-cells: 568.5;T-cells: 241.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0"	"Lineage enriched"	"Detected in all"	7	"T-cells: 1678.5"	"Cancer enriched"	"Detected in single"	8	"lymphoma: 1.7"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells"					"Low region specificity"	"Detected in many"			HPA029200	Enhanced				"Secreted to blood"	NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 54: Lymphoma - Cytokine signaling"	"Cluster 7: NK-cells - Immune response regulation"			"HPA029200: AB_10602908"	"unprognostic (3.72e-3)"	"unprognostic (1.47e-3)"	"unprognostic (5.35e-2)"	"prognostic favorable (2.00e-6)"	"unprognostic (8.80e-2)"	"unprognostic (1.65e-3)"	"unprognostic (2.08e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.62e-2)"	"unprognostic (4.41e-2)"	"unprognostic (1.14e-1)"	"unprognostic (2.68e-1)"	"prognostic unfavorable (1.74e-6)"	"unprognostic (1.23e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.35e-2)"	"unprognostic (2.77e-3)"
GZMM	"LMET1, MET1"	ENSG00000197540	"Granzyme M"	P51124	19	544034-549924	"Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Cytolysis, Immunity, Innate immunity"	"Hydrolase, Protease, Serine protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 21.6;lymphoid tissue: 22.7"	"Group enriched"	"Detected in many"	41	"NK-cells: 678.2;T-cells: 222.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 583.9"	"Group enriched"	"Detected in all"	33	"NK-cells: 194.9;T-cells: 583.9"	"Cancer enhanced"	"Detected in some"		"Leukemia: 5.6"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA015624	Enhanced				"Secreted to blood"	NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"			"HPA015624: AB_2669245"	"unprognostic (2.97e-3)"	"unprognostic (2.29e-3)"	"unprognostic (7.53e-2)"	"prognostic favorable (1.89e-4)"	"unprognostic (1.07e-1)"	"prognostic favorable (1.87e-7)"	"unprognostic (2.35e-1)"	"unprognostic (7.46e-2)"	"unprognostic (1.67e-1)"	"unprognostic (4.98e-2)"	"unprognostic (4.53e-2)"	"unprognostic (7.94e-2)"	"prognostic unfavorable (1.21e-4)"	"unprognostic (1.32e-1)"	"unprognostic (9.51e-2)"	"unprognostic (2.69e-3)"	"unprognostic (9.94e-2)"
KLRB1	"CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A"	ENSG00000111796	"Killer cell lectin like receptor B1"	Q12918	12	9594551-9607916	"CD markers, Predicted membrane proteins"		Receptor		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 47.4;lymphoid tissue: 36.4"	"Group enriched"	"Detected in many"	7	"NK-cells: 1508.8;T-cells: 767.7"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in all"		"MAIT T-cell: 2177.1"	"Group enriched"	"Detected in all"	140	"NK-cells: 756.7;T-cells: 2177.1"	"Not detected"	"Not detected"			"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells"					"Not detected"	"Not detected"			HPA039113	Approved		Uncertain	Nucleoplasm,Cytosol		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 2: Immune cells - Immune response"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"	Nucleoplasm	Cytosol	"HPA039113: AB_10674979"	"prognostic favorable (3.51e-5)"	"unprognostic (1.23e-3)"	"unprognostic (7.03e-3)"	"prognostic favorable (1.42e-5)"	"unprognostic (1.69e-1)"	"prognostic favorable (6.99e-5)"	"unprognostic (1.54e-3)"	"unprognostic (7.15e-3)"	"unprognostic (4.12e-1)"	"unprognostic (8.23e-3)"	"unprognostic (3.57e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.17e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.34e-1)"	"prognostic favorable (5.61e-4)"	"unprognostic (1.17e-2)"
KLRC4	NKG2-F	ENSG00000183542	"Killer cell lectin like receptor C4"	O43908	12	10407382-10409757	"Predicted membrane proteins, Transporters"		Receptor		"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Tissue enhanced"	"Detected in some"		"lymphoid tissue: 9.4"	"Group enriched"	"Detected in some"	7	"NK-cells: 25.4;T-cells: 13.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	20	"gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7"	"Group enriched"	"Detected in many"	59	"NK-cells: 4.7;T-cells: 8.2"	"Cancer enhanced"	"Detected in some"		"lymphoma: 8.0"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Thyroid - T-cells"															NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"				"unprognostic (3.96e-2)"	"unprognostic (1.35e-2)"	"unprognostic (4.60e-1)"		"unprognostic (7.00e-2)"	"unprognostic (1.55e-4)"		"unprognostic (1.89e-2)"	"unprognostic (1.52e-1)"	"unprognostic (3.32e-1)"	"unprognostic (2.92e-1)"	"unprognostic (4.36e-1)"	"unprognostic (3.44e-7)"	"unprognostic (1.49e-1)"	"unprognostic (2.85e-1)"	"unprognostic (2.68e-1)"	"unprognostic (5.51e-3)"
KLRK1	"CD314, D12S2489E, KLR, NKG2-D, NKG2D"	ENSG00000213809	"Killer cell lectin like receptor K1"	P26718	12	10372353-10391874	"Cancer-related genes, CD markers, Predicted membrane proteins, Transporters"	"Adaptive immunity, Differentiation, Immunity, Innate immunity"	Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 22.1;lymphoid tissue: 42.9"	"Group enriched"	"Detected in some"	5	"NK-cells: 26.5;T-cells: 41.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	40	"gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8"	"Group enriched"	"Detected in all"	50	"NK-cells: 335.8;T-cells: 287.4"	"Group enriched"	"Detected in some"	11	"Leukemia: 10.3;lymphoma: 33.7"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"CAB021896, HPA068877"	Enhanced		Supported	"Plasma membrane"		NA	NA		47000	"Cluster 48: NK-cells - Unknown function"	"Cluster 2: Immune cells - Immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 2: T-cells - T-cell receptor"	"Plasma membrane"		"CAB021896: , HPA068877: AB_2686052"	"unprognostic (3.34e-4)"	"unprognostic (2.65e-4)"	"unprognostic (3.25e-1)"	"unprognostic (2.59e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.01e-5)"	"unprognostic (5.61e-4)"	"unprognostic (1.00e-3)"	"unprognostic (1.33e-1)"	"unprognostic (9.22e-2)"	"unprognostic (1.28e-2)"	"unprognostic (2.10e-2)"	"unprognostic (6.56e-10)"	"unprognostic (1.24e-2)"	"unprognostic (6.32e-2)"	"unprognostic (7.59e-2)"	"unprognostic (7.08e-10)"
NKG7	"GIG1, GMP-17"	ENSG00000105374	"Natural killer cell granule protein 7"	Q16617	19	51371606-51372701	"Predicted intracellular proteins, Predicted membrane proteins"	"Cytolysis, Inflammatory response"			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	8	"bone marrow: 602.6;lymphoid tissue: 154.6"	"Cell type enriched"	"Detected in many"	5	"NK-cells: 6101.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8"	"Group enriched"	"Detected in all"	44	"NK-cells: 4796.8;T-cells: 6827.0"	"Group enriched"	"Detected in some"	26	"Leukemia: 62.9;lymphoma: 64.7"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA071454			Approved	Vesicles		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 54: Lymphoma - Cytokine signaling"	"Cluster 7: NK-cells - Immune response regulation"	Vesicles		"HPA071454: AB_2686399"	"unprognostic (1.56e-2)"	"unprognostic (1.05e-2)"	"unprognostic (6.54e-2)"	"prognostic favorable (7.42e-6)"	"unprognostic (1.27e-2)"	"unprognostic (3.25e-3)"	"unprognostic (2.96e-3)"	"unprognostic (2.14e-1)"	"unprognostic (3.22e-3)"	"unprognostic (3.89e-3)"	"unprognostic (3.39e-1)"	"unprognostic (9.93e-2)"	"prognostic unfavorable (3.32e-6)"	"unprognostic (7.62e-3)"	"unprognostic (2.61e-1)"	"unprognostic (1.30e-2)"	"unprognostic (6.44e-3)"
PYHIN1	"IFIX, MGC23885"	ENSG00000163564	"Pyrin and HIN domain family member 1"	Q6K0P9	1	158930796-158977059	"Predicted intracellular proteins"	"Cell cycle"		"Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"lymphoid tissue: 23.1"	"Group enriched"	"Detected in some"	12	"NK-cells: 289.6;T-cells: 96.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Group enriched"	"Detected in many"	4	"gdT-cell: 97.3;MAIT T-cell: 56.3;memory CD4 T-cell: 40.8;memory CD8 T-cell: 74.7;naive CD8 T-cell: 45.1;NK-cell: 36.8;T-reg: 67.3"	"Group enriched"	"Detected in many"	5	"NK-cells: 36.8;T-cells: 97.3"	"Cancer enriched"	"Detected in some"	5	"lymphoma: 13.8"	"Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells"									"HPA051224, HPA055373"	Enhanced		Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"	Nucleoli	Nucleoplasm	"HPA051224: AB_2681394, HPA055373: "	"unprognostic (1.64e-3)"	"unprognostic (1.75e-3)"	"unprognostic (2.93e-3)"	"unprognostic (2.64e-3)"	"unprognostic (3.99e-2)"	"unprognostic (3.57e-3)"	"unprognostic (2.44e-3)"	"unprognostic (2.10e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.47e-3)"	"unprognostic (3.94e-2)"	"unprognostic (2.23e-1)"	"unprognostic (1.70e-6)"	"unprognostic (1.83e-1)"	"unprognostic (2.31e-1)"	"unprognostic (2.76e-2)"	"unprognostic (4.45e-3)"