Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AARD "C8orf85, LOC441376" ENSG00000205002 "Alanine and arginine rich domain containing protein" Q4LEZ3 8 116938207-116944487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.5;urinary bladder: 7.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.6;Breast glandular cells: 27.0;Breast myoepithelial cells: 30.9;granulocytes: 18.7;Sertoli cells: 63.6;Spermatocytes: 45.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 27.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 10 "breast cancer: 39.3;Sarcoma: 23.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 4 "midbrain: 4.4" HPA068290 Approved "Lipid droplets" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 65: Breast cancer - Unknown function" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Lipid droplets" "HPA068290: " "unprognostic (5.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" "unprognostic (7.28e-8)" "unprognostic (3.42e-2)" "unprognostic (4.32e-3)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (8.57e-3)" "unprognostic (4.20e-1)" "unprognostic (2.23e-6)" "unprognostic (1.67e-1)" "unprognostic (9.78e-3)" "unprognostic (3.77e-2)" "unprognostic (5.27e-4)" ABCC9 "CMD1O, SUR2" ENSG00000069431 "ATP binding cassette subfamily C member 9" O60706 12 21797389-21942529 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport Receptor "Atrial fibrillation, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Cardiomyocytes: 37.4;Hepatocytes: 84.2;Sertoli cells: 47.0;Skeletal myocytes: 54.4;Smooth muscle cells: 91.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007279 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 72: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA007279: AB_1844435" "unprognostic (4.82e-2)" "unprognostic (3.62e-2)" "unprognostic (5.51e-4)" "unprognostic (1.09e-1)" "unprognostic (1.09e-1)" "unprognostic (8.30e-2)" "unprognostic (3.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.47e-2)" "unprognostic (8.72e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-1)" "prognostic unfavorable (1.85e-5)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (3.10e-3)" "unprognostic (8.22e-5)" ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.8;retina: 15.6;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Muller glia cells: 167.7" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.0;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (granular)" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "HPA002873: AB_2220573" "unprognostic (6.61e-2)" "unprognostic (3.49e-2)" "unprognostic (2.92e-3)" "unprognostic (1.99e-3)" "unprognostic (4.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" "unprognostic (4.31e-2)" "unprognostic (6.27e-2)" "unprognostic (3.30e-1)" "unprognostic (3.35e-1)" "unprognostic (1.70e-3)" "unprognostic (3.16e-2)" "unprognostic (9.62e-2)" "unprognostic (3.18e-3)" "unprognostic (1.68e-1)" ABLIM2 KIAA1808 ENSG00000163995 "Actin binding LIM protein family member 2" Q6H8Q1 4 7965310-8158832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 204.8;tongue: 73.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 92.0;Inhibitory neurons: 66.1;Skeletal myocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035808 Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Mitochondria Nucleoplasm "HPA035808: AB_10601962" "unprognostic (7.57e-2)" "unprognostic (3.24e-3)" "unprognostic (7.78e-2)" "unprognostic (3.33e-1)" "unprognostic (2.86e-2)" "unprognostic (6.09e-2)" "unprognostic (1.49e-2)" "unprognostic (5.54e-2)" "unprognostic (1.46e-1)" "unprognostic (5.01e-3)" "unprognostic (2.04e-2)" "unprognostic (3.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.32e-2)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.45e-2)" ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 180.4;Cardiomyocytes: 69.9;Hepatocytes: 95.2;Oligodendrocyte precursor cells: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.2" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 325.3;Hepatocytes: 791.9;Proximal enterocytes: 428.9;Proximal tubular cells: 528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Group enriched" "Detected in all" 4 "Cardiomyocytes: 640.9;Distal tubular cells: 236.3;Hepatocytes: 282.5;Proximal tubular cells: 529.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 825.5;Distal tubular cells: 562.9;Hepatocytes: 785.7;Proximal tubular cells: 1461.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 754.0;Hepatocytes: 295.9;Late spermatids: 302.8;Proximal tubular cells: 492.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 61: Liver - Metabolism" "Cluster 49: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 30.2;Proximal enterocytes: 19.5;Proximal tubular cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 12.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.6;Proximal enterocytes: 30.1;Proximal tubular cells: 40.8" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.8;liver cancer: 3.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Astrocytes: 113.2;Early spermatids: 68.6;Inhibitory neurons: 271.2;Late spermatids: 114.9;Oligodendrocyte precursor cells: 323.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.3;Fibroblasts: 9.4;Microglial cells: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 2: DU4475 - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 15.3;Intestinal goblet cells: 7.2;Plasma cells: 5.8;Proximal enterocytes: 5.9;Proximal tubular cells: 25.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 23.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Ductal cells: 12.2;Excitatory neurons: 17.8;Muller glia cells: 41.6;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 29.7" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 68: Kidney - Mixed function" "Cluster 68: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;brain: 101.4;lymphoid tissue: 54.1" "Cell type enhanced" "Detected in some" "B-cells: 6.2;Gastric mucus-secreting cells: 1.8;Plasma cells: 10.5;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 101.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 44.1;Myeloma: 41.0" "Kidney - Endothelial cells" "Region enriched" "Detected in many" 9 "basal ganglia: 399.8" "Region enriched" "Detected in many" 50 "basal ganglia: 142.2" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "granulocytes: 11.6;Hofbauer cells: 16.9;Kupffer cells: 13.7;Late spermatids: 18.0;Macrophages: 43.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 62: Granulocytes - Innate immune response" "Cluster 69: Macrophages - Innate immune response" AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 77.2;Cardiomyocytes: 43.6;Early spermatids: 95.1;Endothelial cells: 74.2;Extravillous trophoblasts: 54.4;Late spermatids: 71.0;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 961.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 297.6" "Cancer enriched" "Detected in single" 167 "liver cancer: 62.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017006, HPA052437" Enhanced Uncertain "Plasma membrane" "Secreted to blood" NA NA 54900000000 8700000000 "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Plasma membrane" "HPA017006: AB_1844635, HPA052437: AB_2732575" "prognostic favorable (1.80e-4)" "unprognostic (5.73e-2)" "unprognostic (4.24e-2)" AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 6 "Cholangiocytes: 993.2;Hepatocytes: 1921.0;Kupffer cells: 509.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 190.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol NA NA 5000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 7 "Hofbauer cells: 2459.1;Kupffer cells: 1902.8;Langerhans cells: 1685.0;Macrophages: 1457.6;monocytes: 3085.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Cancer enriched" "Detected in some" 28 "Leukemia: 77.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 151.2;Hepatocytes: 230.2;Proximal tubular cells: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 940.7;Proximal tubular cells: 1043.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol NA NA 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 17: RS4;11 - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favorable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favorable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 380.9;Cholangiocytes: 313.7;Exocrine glandular cells: 438.2;Hepatocytes: 456.7;Proximal enterocytes: 617.1;Proximal tubular cells: 502.4" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1700.4" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "liver: 212494.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 60343.6" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 24 "liver cancer: 2047.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA 40000000000000 "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 67.4;Ductal cells: 57.9;Hepatocytes: 116.1;Proximal tubular cells: 171.4;Theca cells: 66.7;Undifferentiated cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1312.6;granulocytes: 632.3;Hofbauer cells: 501.4;Langerhans cells: 421.8;Macrophages: 563.9;NK-cells: 345.3;T-cells: 308.1" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Group enriched" "Detected in many" 6 "Leukemia: 131.8;lymphoma: 164.0;Myeloma: 44.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" ALX1 CART1 ENSG00000180318 "ALX homeobox 1" Q15699 12 85280220-85301784 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 3.9;kidney: 6.1" "Cell type enriched" "Detected in some" 6 "Melanocytes: 41.8" "Cancer enriched" "Detected in some" 10 "melanoma: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 20.1" "Kidney - Fibroblasts, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001598, HPA018905" Uncertain Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nuclear bodies" "Nucleoplasm, Golgi apparatus" "HPA001598: AB_1078400, HPA018905: AB_1844783" "unprognostic (4.92e-3)" "unprognostic (8.09e-2)" "unprognostic (1.09e-3)" "unprognostic (1.84e-1)" "unprognostic (6.24e-2)" "unprognostic (2.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-5)" "unprognostic (8.97e-2)" "unprognostic (1.43e-1)" AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.0;Hepatocytes: 18.7;Late spermatids: 15.0;Proximal tubular cells: 40.2" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Stomach - Chief cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 134.6" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Esophageal cancer: 67.9;head and neck cancer: 73.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 29: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 84.4;Leydig cells: 430.0;Peritubular cells: 209.8;Schwann cells: 94.3;Smooth muscle cells: 75.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.0" "Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" ANKRD30B NY-BR-1.1 ENSG00000180777 "Ankyrin repeat domain 30B" Q9BXX2 18 14728272-14854038 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 8.2" "Group enriched" "Detected in some" 6 "Excitatory neurons: 32.0;Inhibitory neurons: 38.2;Spermatocytes: 17.7" "Cancer enriched" "Detected in single" 5 "breast cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.3;Sarcoma: 5.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Chief cells, Testis - Early spermatids" "HPA060455, HPA071849" Uncertain Approved Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 65: Breast cancer - Unknown function" "Cluster 37: Neurons - Neuronal signaling" Nucleoli "HPA060455: AB_2684282, HPA071849: " "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (9.74e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-9)" "unprognostic (1.38e-2)" "unprognostic (1.53e-1)" "unprognostic (7.98e-2)" ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 51.7;Fibroblasts: 35.2;Leydig cells: 37.5;Muller glia cells: 50.3;Peritubular cells: 54.0;Serous glandular cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" APCDD1 B7323 ENSG00000154856 "APC down-regulated 1" Q8J025 18 10454635-10489949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 129.8" "Cell type enhanced" "Detected in many" "Astrocytes: 116.7;Cholangiocytes: 102.0;Endometrial stromal cells: 424.2;Melanocytes: 106.2;Oligodendrocyte precursor cells: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 129.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 52: Endometrial stromal cells - ECM organization" "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.39e-4)" "prognostic favorable (8.23e-4)" "unprognostic (5.61e-3)" "unprognostic (6.79e-3)" "unprognostic (1.24e-1)" "unprognostic (5.59e-3)" "unprognostic (2.59e-2)" "unprognostic (3.14e-1)" "unprognostic (7.77e-2)" "unprognostic (2.04e-3)" "unprognostic (1.77e-1)" "unprognostic (3.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" APELA "ELA, Ende, tdl" ENSG00000248329 "Apelin receptor early endogenous ligand" P0DMC3 4 164877178-164898965 "Predicted secreted proteins" "Angiogenesis, Differentiation, Gastrulation" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.2;prostate: 4.2" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 28.6;Prostatic glandular cells: 11.3;Proximal tubular cells: 37.7;Syncytiotrophoblasts: 34.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 8.9;testis cancer: 25.1" "Kidney - Ascending Loop of Henle cells" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: BEWO - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (2.97e-2)" "unprognostic (6.97e-2)" "unprognostic (9.83e-4)" "unprognostic (8.92e-3)" "unprognostic (1.43e-3)" "unprognostic (4.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (3.38e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-1)" "unprognostic (8.35e-2)" "unprognostic (1.95e-4)" APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;placenta: 54.0" "Cell type enhanced" "Detected in some" "Astrocytes: 7.9;Breast myoepithelial cells: 8.2;Cardiomyocytes: 14.2;Endothelial cells: 43.5" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "prostate cancer: 70.4" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 830.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Cancer enhanced" "Detected in many" "Brain cancer: 65.9;Leukemia: 75.8;liver cancer: 82.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Macrophages" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 8379.2;Hofbauer cells: 5636.7;Leydig cells: 2655.2;Melanocytes: 3312.6;Muller glia cells: 8525.9;Peritubular cells: 4801.9;Proximal tubular cells: 6176.1;Theca cells: 8535.1" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 529.4" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 12: Non-specific - Chromatin organization" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" AQP11 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.6;liver: 16.1" "Cell type enhanced" "Detected in many" "Early spermatids: 45.7;Hepatocytes: 37.8;Late spermatids: 64.7;Proximal enterocytes: 33.8;Spermatocytes: 50.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077460 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA077460: " "unprognostic (4.95e-2)" "unprognostic (7.61e-2)" "unprognostic (2.15e-2)" "unprognostic (9.62e-5)" "unprognostic (2.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "prognostic favorable (9.89e-4)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (2.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.66e-3)" ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 31.5;Endothelial cells: 31.1;Horizontal cells: 16.0;Microglial cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" ARHGEF25 "GEFT, p63RhoGEF" ENSG00000240771 "Rho guanine nucleotide exchange factor 25" Q86VW2 12 57610180-57617245 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 151.2" "Cell type enhanced" "Detected in some" "Astrocytes: 8.2;Excitatory neurons: 15.1;Inhibitory neurons: 8.3;Microglial cells: 8.2;Smooth muscle cells: 8.0;Thymic epithelial cells: 4.7" "Cancer enhanced" "Detected in all" "glioma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052016 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 72: Smooth muscle cells - ECM organization" "HPA052016: AB_2681695" "unprognostic (8.43e-2)" "unprognostic (4.24e-3)" "unprognostic (2.13e-3)" "unprognostic (6.95e-3)" "unprognostic (8.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.45e-2)" "unprognostic (2.39e-2)" "unprognostic (4.63e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.20e-7)" "unprognostic (1.41e-2)" "unprognostic (2.03e-1)" "unprognostic (6.82e-3)" "unprognostic (3.22e-3)" ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934521-2968475 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.6;liver: 86.3;pancreas: 105.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 32.1;Enteroendocrine cells: 41.5;Hepatocytes: 65.7;Paneth cells: 47.6;Proximal enterocytes: 48.5;Proximal tubular cells: 78.3;Undifferentiated cells: 58.3" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 32.0;liver cancer: 34.8" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 68: Kidney - Mixed function" "Cluster 26: Intestinal epithelial cells - Absorption" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.2;Melanocytes: 78.4;Oligodendrocytes: 204.8;Peritubular cells: 48.3;Proximal tubular cells: 61.2;Schwann cells: 52.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.9;Fibroblasts: 68.4;Microglial cells: 23.7;Sertoli cells: 22.1;Smooth muscle cells: 63.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 19.7;Cytotrophoblasts: 13.6;Distal tubular cells: 18.7;Ionocytes: 11.6;Melanocytes: 8.7;Salivary duct cells: 24.8;Serous glandular cells: 11.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 9.9;Gastric cancer: 11.2" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 127.4;salivary gland: 139.8" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 29.3;Distal tubular cells: 80.9" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 16.3;ovarian cancer: 12.8" "Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: AB_2674072" "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2106.8;Inhibitory neurons: 1445.3;Oligodendrocyte precursor cells: 1395.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1516.2" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 9.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133400056-133475222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Plasma cells: 17.9" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "T-reg: 13.4" "Lineage enriched" "Detected in single" 43 "T-cells: 13.4" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Kidney - Intercalated cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA038464: AB_10672746, HPA062959: AB_2684912" "unprognostic (1.58e-3)" "unprognostic (7.47e-4)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (9.59e-2)" "unprognostic (4.04e-5)" "unprognostic (8.13e-2)" "unprognostic (5.57e-2)" "unprognostic (6.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.74e-2)" "unprognostic (4.70e-2)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.23e-2)" "unprognostic (2.21e-2)" C16orf87 ENSG00000155330 "Chromosome 16 open reading frame 87" Q6PH81 16 46796603-46831180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 134.0;Spermatocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041179 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: Non-specific - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "Nuclear bodies" "HPA041179: AB_10795002" "unprognostic (2.44e-1)" "unprognostic (4.21e-1)" "unprognostic (2.91e-1)" "unprognostic (1.80e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (7.95e-5)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (3.21e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (9.90e-2)" "unprognostic (1.35e-2)" "unprognostic (2.08e-2)" "unprognostic (2.66e-1)" "unprognostic (6.61e-3)" "unprognostic (1.84e-2)" C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Group enriched" "Detected in some" 6 "Horizontal cells: 293.5;Oligodendrocyte precursor cells: 80.9;Thymic epithelial cells: 114.1" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 86.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Cholangiocyte, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Kidney - Mixed function" "Cluster 9: Neurons - Nervous system development" Vesicles Cytosol "HPA071349: " "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 17.7;Leydig cells: 22.0;Peritubular cells: 30.8;Smooth muscle cells: 21.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Sarcoma: 7.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Group enriched" "Detected in many" 4 "granulocytes: 50.8;Hofbauer cells: 173.4;Kupffer cells: 115.3;Macrophages: 148.5;monocytes: 107.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" C4orf54 "FOPV, LOC285556" ENSG00000248713 "Chromosome 4 open reading frame 54" D6RIA3 4 99636529-99654648 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 72.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 13.2;Excitatory neurons: 5.4;Sertoli cells: 5.5;Skeletal myocytes: 29.7" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Kidney - Ascending Loop of Henle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" HPA079091 Approved "Nuclear bodies,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 27: Skeletal myocytes - Muscle contraction" "Nuclear bodies" Cytosol "HPA079091: " "unprognostic (3.91e-2)" "unprognostic (3.76e-1)" "unprognostic (4.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.76e-2)" "unprognostic (4.00e-3)" "unprognostic (2.31e-3)" "unprognostic (1.50e-1)" "unprognostic (4.31e-2)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" "unprognostic (2.20e-1)" "unprognostic (2.42e-3)" "unprognostic (1.89e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 221.3;Kupffer cells: 524.8;Macrophages: 438.4;monocytes: 1802.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Heart muscle - Macrophages, Kidney - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 5 "Fibroblasts: 708.6;Leydig cells: 1128.7;Theca cells: 421.0" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Neuroblastoma: 31.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1268.6;Leydig cells: 1812.3;Peritubular cells: 2058.2;Sertoli cells: 1210.7;Smooth muscle cells: 2342.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cancer enhanced" "Detected in all" "testis cancer: 491.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.8;Gastric mucus-secreting cells: 22.7;Paneth cells: 12.4;Proximal enterocytes: 23.6;Proximal tubular cells: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 184.3;non-classical monocyte: 216.9" "Lineage enriched" "Detected in many" 7 "monocytes: 216.9" "Cancer enhanced" "Detected in all" "Myeloma: 77.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" CAPN12 ENSG00000182472 "Calpain 12" Q6ZSI9 19 38730187-38769904 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 22.8;liver: 24.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.3;NK-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "basophil: 59.3;NK-cell: 25.5" "Group enriched" "Detected in many" 9 "granulocytes: 59.3;NK-cells: 25.5" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 3.0" HPA053322 Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 7: NK-cells - Immune response regulation" "Focal adhesion sites" Nucleoplasm "HPA053322: AB_2682111" "unprognostic (1.81e-1)" "unprognostic (4.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-3)" "unprognostic (7.20e-2)" "unprognostic (2.45e-2)" "unprognostic (1.29e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (5.90e-6)" "unprognostic (7.04e-2)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (4.59e-2)" CAPN14 ENSG00000214711 "Calpain 14" A8MX76 2 31173056-31233858 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "esophagus: 144.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.9;Excitatory neurons: 3.1;granulocytes: 3.3;Inhibitory neurons: 4.1;Squamous epithelial cells: 9.4" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 2.5" "Kidney - Endothelial cells" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (5.81e-3)" "unprognostic (1.20e-1)" "unprognostic (4.57e-2)" "unprognostic (1.88e-2)" "unprognostic (3.85e-2)" "unprognostic (3.30e-1)" "unprognostic (3.61e-2)" "unprognostic (4.67e-2)" "unprognostic (1.71e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" "unprognostic (1.60e-1)" "unprognostic (3.71e-4)" "unprognostic (8.42e-2)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (4.47e-4)" CAPZA3 "CAPPA3, Gsg3" ENSG00000177938 "Capping actin protein of muscle Z-line subunit alpha 3" Q96KX2 12 18738119-18739188 "Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "testis: 182.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 7677.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA038688 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 51: Late spermatids - Spermatogenesis" "HPA038688: AB_2676151" "unprognostic (5.56e-2)" "unprognostic (1.43e-1)" "unprognostic (4.45e-3)" "unprognostic (5.67e-2)" CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1272.2;Alveolar cells type 1: 281.7;Cardiomyocytes: 187.7;Endothelial cells: 437.4;granulocytes: 241.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 4: Platelets - Platelet activation" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" CCDC150 FLJ39660 ENSG00000144395 "Coiled-coil domain containing 150" Q8NCX0 2 196639554-196763490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;testis: 4.9" "Cell type enhanced" "Detected in many" "Early spermatids: 72.9;Granulosa cells: 15.6;Late spermatids: 16.6;Oligodendrocytes: 15.5;Spermatocytes: 31.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048104 Uncertain Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 45: Non-specific - Cell proliferation" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA048104: AB_2680264" "unprognostic (1.92e-1)" "unprognostic (3.75e-1)" "unprognostic (2.95e-1)" "unprognostic (2.58e-4)" "unprognostic (9.88e-2)" "unprognostic (1.42e-3)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (5.91e-4)" "unprognostic (2.01e-2)" "unprognostic (3.16e-2)" "unprognostic (9.17e-3)" "unprognostic (5.66e-4)" "unprognostic (7.29e-2)" "unprognostic (1.99e-2)" "unprognostic (4.35e-2)" "unprognostic (2.69e-5)" CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 43.9;Excitatory neurons: 53.7;Glandular and luminal cells: 41.2;Inhibitory neurons: 54.3;Syncytiotrophoblasts: 73.4;Thymic epithelial cells: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.7;naive B-cell: 83.6" "Lineage enriched" "Detected in many" 23 "B-cells: 83.6" "Cancer enhanced" "Detected in many" "skin cancer: 32.3" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 66: Endothelial cells - Angiogenesis" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "Hofbauer cells: 43.1;Kupffer cells: 12.5;Langerhans cells: 16.2;Macrophages: 27.4;monocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 5.3;lymphoma: 5.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 316.5;Endothelial cells: 281.4;Kupffer cells: 156.2;Macrophages: 116.9;monocytes: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "Leukemia: 18.7;lymphoma: 10.5;ovarian cancer: 5.0" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105, DFNB32" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520277 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 141.4;Early spermatids: 122.5;Late spermatids: 211.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 18.4" "Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" CDC20B FLJ37927 ENSG00000164287 "Cell division cycle 20B" Q86Y33 5 55112971-55173177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.1;kidney: 1.1;testis: 2.6" "Cell type enhanced" "Detected in some" "Club cells: 4.8;Endometrial ciliated cells: 21.3;Ionocytes: 10.5;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in some" "endometrial cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Esophageal cancer: 1.0" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053900 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" "HPA053900: AB_2682299" "unprognostic (7.39e-3)" "unprognostic (1.02e-1)" "unprognostic (8.19e-2)" "unprognostic (1.78e-3)" "unprognostic (9.94e-2)" "unprognostic (1.59e-2)" "unprognostic (3.12e-1)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (7.84e-3)" "unprognostic (2.83e-2)" "unprognostic (3.06e-1)" "unprognostic (5.15e-4)" "unprognostic (1.99e-2)" "unprognostic (2.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.29e-2)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 296.8;Endothelial cells: 212.8;Extravillous trophoblasts: 50.9;Late spermatids: 86.2;Syncytiotrophoblasts: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 13.1;Rhabdoid: 12.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.4;fallopian tube: 108.8" "Cell type enhanced" "Detected in many" "Astrocytes: 165.4;Endometrial ciliated cells: 139.7;Enteroendocrine cells: 92.1;Excitatory neurons: 69.1;Inhibitory neurons: 62.5;Respiratory ciliated cells: 291.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lymphoma: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" HPA011218 Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" "HPA011218: AB_1078886" "unprognostic (4.38e-4)" "unprognostic (9.18e-2)" "unprognostic (8.16e-3)" "unprognostic (8.08e-3)" "unprognostic (5.23e-2)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.70e-3)" "unprognostic (3.51e-3)" CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 591.7;Extravillous trophoblasts: 1810.8;Syncytiotrophoblasts: 2119.7;Theca cells: 517.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Podocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: DU4475 - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Group enriched" "Detected in some" 7 "Hofbauer cells: 9.5;Kupffer cells: 30.4;Macrophages: 22.3;monocytes: 16.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.8" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 703.3;liver: 345.7" "Group enriched" "Detected in all" 4 "Distal enterocytes: 785.7;Proximal enterocytes: 2644.1" "Cancer enhanced" "Detected in all" "liver cancer: 104.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558, HPA074629: " "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" CFAP45 "CCDC19, NESG1" ENSG00000213085 "Cilia and flagella associated protein 45" Q9UL16 1 159872364-159900165 "Predicted intracellular proteins" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 13.5;fallopian tube: 44.8;testis: 28.4" "Group enriched" "Detected in many" 4 "Early spermatids: 278.1;Endometrial ciliated cells: 105.4;Late spermatids: 79.8;Respiratory ciliated cells: 161.9" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 10.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "eosinophil: 3.0;neutrophil: 2.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.1" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042204, HPA043618" Enhanced Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" Nucleoplasm "HPA042204: AB_10966555, HPA043618: AB_10959305" "unprognostic (1.88e-1)" "unprognostic (4.15e-2)" "unprognostic (3.95e-1)" "unprognostic (5.18e-3)" "unprognostic (4.78e-3)" "unprognostic (1.49e-1)" "unprognostic (8.80e-4)" "unprognostic (2.57e-1)" "unprognostic (1.76e-1)" "unprognostic (5.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-12)" "unprognostic (2.95e-1)" "unprognostic (1.87e-1)" "unprognostic (3.83e-3)" "unprognostic (1.65e-1)" CFAP58 "bA554P13.1, C10orf80, CCDC147, FLJ35908" ENSG00000120051 "Cilia and flagella associated protein 58" Q5T655 10 104353833-104455102 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.4;testis: 13.4" "Cell type enhanced" "Detected in some" "Early spermatids: 84.6;Endometrial ciliated cells: 25.3;Late spermatids: 57.0;Respiratory ciliated cells: 27.2;Spermatocytes: 30.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.9" "HPA036555, HPA071938" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 56: Ciliated cells - Cilium assembly" Vesicles "Plasma membrane, Cytosol" "HPA036555: AB_10673622, HPA071938: " "unprognostic (5.32e-1)" "unprognostic (2.59e-1)" "unprognostic (6.26e-2)" "unprognostic (1.57e-3)" "unprognostic (5.41e-3)" "unprognostic (1.01e-1)" "unprognostic (9.62e-2)" "unprognostic (5.64e-2)" "unprognostic (3.11e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-2)" "unprognostic (3.15e-1)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (6.81e-2)" "unprognostic (4.19e-2)" "unprognostic (1.59e-1)" CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 37.6;liver: 35.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 64.5;Proximal tubular cells: 73.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 3.1;T-reg: 1.3" "Group enriched" "Detected in many" 17 "granulocytes: 3.1;T-cells: 1.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036633, HPA058130" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "HPA036633: AB_10670841, HPA058130: AB_2683615" "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favorable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.2;Basal respiratory cells: 93.4;Ductal cells: 91.5;Hofbauer cells: 285.3;Thymic epithelial cells: 209.6" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 264.1;Brain cancer: 118.6" "Kidney - Podocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524155-126543291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 59.6;testis: 18.3" "Cell type enhanced" "Detected in some" "Early spermatids: 144.7;Hepatocytes: 33.5;Spermatocytes: 103.5" "Group enriched" "Detected in many" 4 "liver cancer: 25.0;renal cancer: 6.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 5 "eosinophil: 155.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 155.2" "Cancer enriched" "Detected in some" 4 "liver cancer: 12.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA067960 Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Golgi apparatus" "HPA067960: " "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (6.42e-4)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (8.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (5.16e-2)" "unprognostic (6.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-2)" CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "monocytes: 75.0;Muller glia cells: 94.1;NK-cells: 148.2;Plasma cells: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1007.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.7" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Smooth muscle cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 470.9;Spermatocytes: 700.6;Spermatogonia: 525.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Unknown function" "Cluster 11: Non-specific - Transcription" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" CLDN19 ENSG00000164007 "Claudin 19" Q8N6F1 1 42733093-42740254 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "choroid plexus: 19.8;kidney: 39.1;placenta: 9.8" "Cell type enriched" "Detected in some" 17 "Extravillous trophoblasts: 265.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "liver cancer: 2.9;testis cancer: 3.5" "Kidney - Ascending Loop of Henle cells" "Region enhanced" "Detected in many" "olfactory bulb: 5.4" "Region enriched" "Detected in many" 6 "spinal cord: 41.8" HPA014412 Supported "Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: Liver cancer - Metabolism" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA014412: " "unprognostic (6.23e-4)" "unprognostic (1.80e-1)" "unprognostic (1.85e-6)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-1)" "unprognostic (9.45e-2)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (7.22e-2)" "unprognostic (8.76e-3)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.29e-3)" CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 114.7;gallbladder: 101.6;kidney: 165.2;seminal vesicle: 90.1" "Cell type enhanced" "Detected in some" "Ductal cells: 74.6;Exocrine glandular cells: 55.0;Hepatocytes: 26.0;Proximal enterocytes: 31.8;Proximal tubular cells: 89.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 53.3;liver cancer: 24.6;pancreatic cancer: 48.5;renal cancer: 87.2;stomach cancer: 30.5" "Region enriched" "Detected in some" 5 "hippocampal formation: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 124.8;colorectal cancer: 47.8;Gastric cancer: 48.7;Kidney cancer: 97.3;liver cancer: 33.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Region enhanced" "Detected in some" "medulla oblongata: 1.7" "CAB002609, HPA051548" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Cell Junctions" "CAB002609: , HPA051548: AB_2681530" "unprognostic (2.31e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-2)" "unprognostic (6.07e-2)" "unprognostic (7.47e-3)" "unprognostic (2.24e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (8.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "prognostic favorable (1.70e-4)" "unprognostic (9.76e-2)" CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 130.6;Fibroblasts: 100.0;Melanocytes: 114.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 288.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: RS4;11 - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 48.6;Cytotrophoblasts: 53.5;Endothelial cells: 35.3;Extravillous trophoblasts: 65.6;Syncytiotrophoblasts: 52.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "testis cancer: 5.6" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 54: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 2.0;Inhibitory neurons: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Sinusoid Endothelial cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 56: Neurons - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 8 "Hofbauer cells: 34.4;Langerhans cells: 94.9;Macrophages: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Cancer enriched" "Detected in single" 141 "Leukemia: 14.0" "Kidney - Macrophages, Prostate - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.2;Excitatory neurons: 26.1;Fibroblasts: 59.3;Inhibitory neurons: 31.3;Peritubular cells: 60.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enhanced" "Detected in some" "B-cells: 16.3;Distal tubular cells: 21.8;granulocytes: 39.9;Ionocytes: 13.8;Salivary duct cells: 18.1;Schwann cells: 37.5" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.5" "Breast - T-cells, Kidney - Intercalated cells, Liver - NK-cells (Liver), Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 46: Granulocytes - Mast cell degranulation" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124915287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 7.9" "Group enriched" "Detected in some" 56 "Excitatory neurons: 545.5;Inhibitory neurons: 884.8;Oligodendrocyte precursor cells: 727.8" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 47: Retina - Visual perception" "Cluster 32: Neurons - Synaptic function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: AB_2686083, HPA069356: AB_2686127" "unprognostic (6.32e-3)" "unprognostic (6.38e-2)" "unprognostic (1.23e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-6)" "unprognostic (3.65e-3)" "unprognostic (5.32e-2)" "unprognostic (9.58e-2)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 101.5;Fibroblasts: 182.8;Schwann cells: 66.2;Smooth muscle cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Brain cancer: 29.5;colorectal cancer: 45.5;Sarcoma: 64.1;thyroid cancer: 21.1" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: NCI-H716 - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 711.3;Fibroblasts: 1913.7;Glandular and luminal cells: 452.3;Leydig cells: 999.0;Pancreatic endocrine cells: 498.1;Peritubular cells: 495.5;Smooth muscle cells: 640.7;Theca cells: 555.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1492.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA068464, HPA068494" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA068464: , HPA068494: " "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 64.5;Cardiomyocytes: 47.4;Extravillous trophoblasts: 87.4;Inhibitory neurons: 61.6;Schwann cells: 70.1;Skeletal myocytes: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 9.0;Brain cancer: 5.0;liver cancer: 5.4;prostate cancer: 10.2;Rhabdoid: 8.4;testis cancer: 11.1" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 2622.9;Fibroblasts: 1426.6;Smooth muscle cells: 709.7;Theca cells: 729.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 1260.1;testis cancer: 954.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 175.7;Excitatory neurons: 182.8;Fibroblasts: 155.6;Smooth muscle cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 466.3;testis cancer: 373.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Hypogonadotropic hypogonadism, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 704.7;Bipolar cells: 616.6;Cone photoreceptor cells: 1283.9;Leydig cells: 497.8;Muller glia cells: 521.8;Peritubular cells: 616.4;Prostatic glandular cells: 924.9;Rod photoreceptor cells: 746.0;Sertoli cells: 514.1" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 342.6;thyroid cancer: 385.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 44: Photoreceptor cells - Visual perception" "Vesicles, Centrosome" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 273.5" "Cell type enhanced" "Detected in many" "Adipocytes: 48.4;Bipolar cells: 30.9;dendritic cells: 38.5;Excitatory neurons: 43.6;Horizontal cells: 69.2;Inhibitory neurons: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.7" "Kidney - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" CPNE6 ENSG00000100884 "Copine 6" O95741 14 24070837-24078100 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.3;retina: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.9;Bipolar cells: 20.2;Horizontal cells: 27.6;Inhibitory neurons: 11.1;Late spermatids: 18.5" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Uterine cancer: 3.3" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031636, HPA076665" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 47: Retina - Visual perception" "Cluster 9: Neurons - Nervous system development" "Golgi apparatus" Vesicles "HPA031636: AB_10601203, HPA076665: " "unprognostic (1.02e-2)" "unprognostic (3.26e-4)" "unprognostic (1.64e-1)" "unprognostic (5.66e-5)" "unprognostic (3.51e-3)" "unprognostic (2.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.09e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" "unprognostic (1.01e-2)" "unprognostic (5.79e-2)" "unprognostic (4.50e-2)" "unprognostic (2.71e-1)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Group enriched" "Detected in some" 4 "B-cells: 41.1;Erythroid cells: 17.2;Hofbauer cells: 17.1;Kupffer cells: 35.6;Macrophages: 45.8;monocytes: 18.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 7 "Leukemia: 3.5;lymphoma: 1.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophil_2, Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Cell type enhanced" "Detected in some" "Adipocytes: 104.1;Endothelial cells: 76.6;Fibroblasts: 199.8;Granulosa cells: 439.7;Kupffer cells: 91.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Brain cancer: 14.3" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 505.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 22575.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" NA NA 820000 "Cluster 83: Testis - Spermatogenesis" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 6: Late spermatids - Spermatogenesis" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 329.8;liver: 254.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 320.3;Hepatocytes: 338.4;Paneth cells: 269.6;Proximal enterocytes: 581.5;Proximal tubular cells: 743.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 690000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632, HPA058848: " "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favorable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favorable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 45.4;Granulosa cells: 32.0;Horizontal cells: 23.1;Muller glia cells: 42.9;Proximal tubular cells: 31.7;Sertoli cells: 110.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Group enriched" "Detected in many" 5 "Extravillous trophoblasts: 116.5;Hofbauer cells: 330.9;Kupffer cells: 139.9;Langerhans cells: 99.2;Macrophages: 223.6;Microglial cells: 131.3;monocytes: 181.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Cancer enhanced" "Detected in many" "Leukemia: 10.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enriched" "Detected in all" 4 "Alveolar cells type 2: 1718.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 41: Alveolar cells - Lung function" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.3;Cytotrophoblasts: 136.3;Extravillous trophoblasts: 179.8;Rod photoreceptor cells: 95.5;Sertoli cells: 152.0;Syncytiotrophoblasts: 74.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Cancer enriched" "Detected in all" 8 "testis cancer: 739.0" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 6: BEWO - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.7;Distal enterocytes: 26.6;Endometrial ciliated cells: 40.2;Glandular and luminal cells: 20.8;Prostatic glandular cells: 81.9;Respiratory ciliated cells: 27.3;Suprabasal keratinocytes: 66.5" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 18.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.6;Basal squamous epithelial cells: 1379.7;Breast myoepithelial cells: 1749.0;Fibroblasts: 1472.7;Glandular and luminal cells: 1617.8;Proximal tubular cells: 3452.0;Suprabasal keratinocytes: 1279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 170.2;head and neck cancer: 230.8" "Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: DU4475 - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "dendritic cells: 334.1;Hofbauer cells: 226.4;Kupffer cells: 358.4;Macrophages: 451.2;monocytes: 516.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Cancer enhanced" "Detected in some" "Leukemia: 17.9;lymphoma: 28.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.6;Leydig cells: 197.5;Peritubular cells: 219.1;Proximal enterocytes: 701.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 102.3;Fibroblasts: 126.4;Kupffer cells: 118.0;Leydig cells: 158.9;Macrophages: 125.8;Peritubular cells: 171.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 145.1;Basal squamous epithelial cells: 38.5;Ionocytes: 109.2;Proximal tubular cells: 65.8" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022261 Enhanced Approved Mitochondria NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Enzymes" "Cluster 5: Bronchus - Unknown function" Mitochondria "HPA022261: AB_1847427" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" CYP4A22 ENSG00000162365 "Cytochrome P450 family 4 subfamily A member 22" Q5TCH4 1 47137435-47149735 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 214.2" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 98.8" "Cancer enriched" "Detected in some" 13 "liver cancer: 20.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 85: Liver - Metabolism" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-2)" "unprognostic (2.88e-3)" "unprognostic (2.76e-3)" "unprognostic (1.50e-3)" "unprognostic (2.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-2)" "unprognostic (5.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.71e-1)" "unprognostic (8.59e-4)" CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 61 "Hepatocytes: 791.7" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 179.1;placenta: 226.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1525.6;Proximal tubular cells: 1866.0;Syncytiotrophoblasts: 1812.1" "Cancer enhanced" "Detected in all" "renal cancer: 52.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.7" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.7" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 130000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: AB_638976, HPA028888: AB_2672814" "unprognostic (1.24e-1)" "unprognostic (7.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (5.37e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.38e-6)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 22.5;Horizontal cells: 23.1;Oligodendrocytes: 25.7;Smooth muscle cells: 29.2" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2831.9;Proximal tubular cells: 2882.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.5;Endometrial stromal cells: 15.5;Endothelial cells: 29.3;Fibroblasts: 18.8;Granulosa cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 12.9;Neuroblastoma: 25.8;Sarcoma: 6.5" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" DDN KIAA0749 ENSG00000181418 Dendrin O94850 12 48995149-48999375 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 165.7;skeletal muscle: 297.1" "Group enriched" "Detected in some" 4 "Collecting duct cells: 5.9;Excitatory neurons: 5.8;Inhibitory neurons: 2.5" "Cancer enhanced" "Detected in some" "glioma: 2.2;head and neck cancer: 2.6" "Group enriched" "Detected in many" 31 "amygdala: 142.5;basal ganglia: 115.5;cerebral cortex: 165.7;hippocampal formation: 126.2;white matter: 54.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 11.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "amygdala: 165.3;basal ganglia: 212.8;cerebral cortex: 178.3;hippocampal formation: 171.2;olfactory bulb: 62.7" HPA060952 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA060952: AB_2684396" "unprognostic (2.80e-2)" "unprognostic (3.19e-3)" "unprognostic (4.56e-2)" "unprognostic (8.10e-3)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (6.20e-5)" "unprognostic (8.61e-4)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (5.08e-2)" "unprognostic (1.37e-6)" "unprognostic (1.72e-2)" "unprognostic (5.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.53e-2)" DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.6;Muller glia cells: 7.7;Oligodendrocytes: 12.5;Proximal enterocytes: 8.9;Proximal tubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 165.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.8;Proximal enterocytes: 78.0;Proximal tubular cells: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 8: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes Microtubules "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.2;lymphoid tissue: 20.9;parathyroid gland: 46.4" "Cell type enriched" "Detected in some" 11 "Distal tubular cells: 118.2" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 6.4;Sarcoma: 5.8" "Kidney - Intercalated cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" DNAJC12 JDP1 ENSG00000108176 "DnaJ heat shock protein family (Hsp40) member C12" Q9UKB3 10 67796669-67838188 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 70.3;liver: 67.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 81.0;Enteroendocrine cells: 137.3;Hepatocytes: 102.7;Pancreatic endocrine cells: 147.7;Proximal tubular cells: 150.5" "Cancer enhanced" "Detected in many" "breast cancer: 22.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 7.7" "Lineage enriched" "Detected in single" 24 "dendritic cells: 7.7" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036289 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 30: Breast - Lactation" "HPA036289: AB_10670794" "unprognostic (1.52e-2)" "unprognostic (3.65e-3)" "unprognostic (4.12e-2)" "unprognostic (2.28e-2)" "unprognostic (5.28e-2)" "unprognostic (6.59e-3)" "unprognostic (6.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (5.05e-2)" "unprognostic (3.97e-2)" "unprognostic (7.31e-3)" "prognostic unfavorable (1.97e-10)" "unprognostic (7.35e-3)" "unprognostic (1.37e-1)" "unprognostic (5.81e-3)" "unprognostic (7.99e-2)" DNPH1 "C6orf108, dJ330M21.3, rcl" ENSG00000112667 "2'-deoxynucleoside 5'-phosphate N-hydrolase 1" O43598 6 43225629-43229481 "Predicted intracellular proteins" "Nucleotide metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 844.2;Proximal tubular cells: 1015.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029675, HPA029676" Enhanced Approved Nucleoplasm,Cytosol No No 540000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm Cytosol "HPA029675: AB_10599998, HPA029676: AB_10599424" "unprognostic (1.12e-2)" "unprognostic (1.38e-1)" "unprognostic (4.03e-3)" "unprognostic (8.24e-3)" "unprognostic (1.69e-1)" "unprognostic (3.53e-2)" "unprognostic (2.61e-1)" "unprognostic (7.72e-2)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (2.25e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-1)" "unprognostic (5.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (5.10e-2)" EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 19 "Extravillous trophoblasts: 590.0;Syncytiotrophoblasts: 298.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cancer enriched" "Detected in many" 5 "lymphoma: 77.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.6;skeletal muscle: 128.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.6;Distal tubular cells: 146.2;Hepatocytes: 182.0;Proximal tubular cells: 187.2" "Cancer enhanced" "Detected in all" "liver cancer: 35.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 120000 "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "HPA038306: AB_10672586" "unprognostic (8.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (5.07e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-1)" "prognostic favorable (3.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (3.91e-4)" ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 260.4;Cytotrophoblasts: 301.8;Distal tubular cells: 366.9;Proximal tubular cells: 504.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 60: Proximal tubular cells - Absorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 57.3;Hepatocytes: 47.5;Leydig cells: 123.8;Peritubular cells: 72.2;Smooth muscle cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 221.0;Endothelial cells: 159.6;Gastric mucus-secreting cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 46.2;Suprabasal keratinocytes: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA001581: AB_2666367, HPA001790: " "unprognostic (9.58e-3)" "unprognostic (1.10e-2)" "unprognostic (3.68e-2)" "unprognostic (1.78e-1)" "unprognostic (6.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-1)" "unprognostic (3.85e-2)" "unprognostic (7.36e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.09e-5)" "unprognostic (3.44e-3)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 793.8;Endothelial cells: 499.6;Hofbauer cells: 263.6;Spermatogonia: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" ELF5 ENSG00000135374 "E74 like ETS transcription factor 5" Q9UKW6 11 34478791-34525193 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 151.2;salivary gland: 147.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 146.7;Breast glandular cells: 154.5;Breast myoepithelial cells: 50.4;Collecting duct cells: 88.6;Mucus glandular cells: 65.1;Serous glandular cells: 92.3" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 18.0;breast cancer: 24.9" "Kidney - Ascending Loop of Henle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062706 Approved Nucleoplasm NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" "Cluster 30: Breast - Lactation" Nucleoplasm "HPA062706: AB_2684841" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (7.55e-2)" "unprognostic (3.31e-2)" "unprognostic (2.41e-4)" "unprognostic (6.90e-2)" "unprognostic (3.93e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.12e-1)" "unprognostic (3.40e-2)" "unprognostic (8.15e-2)" "unprognostic (3.15e-2)" "unprognostic (1.78e-3)" "unprognostic (3.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (2.86e-1)" ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 32.8;pituitary gland: 21.7;retina: 32.6;skin 1: 28.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 27.8;Excitatory neurons: 124.4;Horizontal cells: 30.8;Inhibitory neurons: 101.5;Oligodendrocyte precursor cells: 77.5" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 25.3" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066479 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Nuclear speckles" "HPA066479: " "unprognostic (2.74e-1)" "unprognostic (1.72e-4)" "unprognostic (2.58e-2)" "unprognostic (9.13e-2)" "unprognostic (3.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-1)" "unprognostic (6.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (6.29e-2)" "unprognostic (9.44e-2)" "unprognostic (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" ELOVL4 "CT118, SCA34, STGD2, STGD3" ENSG00000118402 "ELOVL fatty acid elongase 4" Q9GZR5 6 79914814-79947553 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, FDA approved drug targets, Ichthyosis, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia, Stargardt disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 105.5;retina: 176.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 89.5;Cone photoreceptor cells: 274.0;Rod photoreceptor cells: 312.7;Suprabasal keratinocytes: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 23.7" "Lineage enriched" "Detected in single" 238 "T-cells: 23.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.1" "Heart muscle - Fibroblasts, Kidney - Podocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 44: Photoreceptor cells - Visual perception" "unprognostic (1.67e-2)" "unprognostic (8.58e-3)" "unprognostic (2.38e-2)" "unprognostic (3.08e-6)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (3.46e-1)" "unprognostic (6.91e-3)" "unprognostic (3.39e-1)" "unprognostic (1.38e-2)" "unprognostic (3.45e-3)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.27e-4)" ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730943-79742219 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 104.6" "Group enriched" "Detected in some" 25 "Hepatocytes: 7.9;Proximal enterocytes: 28.1;Proximal tubular cells: 8.6" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA024603 Approved "Intracellular and membrane" NA NA 450000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 302.7;Inhibitory neurons: 232.4;Late spermatids: 306.6;Oligodendrocytes: 150.3;Syncytiotrophoblasts: 256.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.4" "Lineage enriched" "Detected in many" 5 "monocytes: 12.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 385.2;Endothelial cells: 271.5;Sertoli cells: 63.6;Smooth muscle cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 15.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 19.0;Squamous epithelial cells: 8.2;Suprabasal keratinocytes: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" EVX1 ENSG00000106038 "Even-skipped homeobox 1" P49640 7 27242700-27250493 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.9;prostate: 3.8;seminal vesicle: 2.9;urinary bladder: 3.3;vagina: 3.5" "Group enriched" "Detected in some" 11 "Early spermatids: 33.3;Late spermatids: 92.8" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.6" "Region enhanced" "Detected in single" "medulla oblongata: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.1" "Kidney - Podocytes, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.0" "Not detected" "Not detected" HPA055132 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "HPA055132: AB_2682707" "unprognostic (2.73e-2)" "unprognostic (3.59e-1)" "unprognostic (4.31e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-3)" "unprognostic (2.08e-2)" "unprognostic (8.48e-3)" "unprognostic (5.94e-2)" "unprognostic (1.26e-8)" "unprognostic (2.94e-1)" "unprognostic (1.39e-1)" "unprognostic (9.12e-2)" "unprognostic (1.83e-2)" EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Endothelial cells: 18.7;Granulosa cells: 19.9;Leydig cells: 16.2;Peritubular cells: 18.3;Theca cells: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 70.0" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.1" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 652.4;Cardiomyocytes: 2566.2;Distal tubular cells: 478.9;Proximal tubular cells: 899.3" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Kupffer cells, Prostate - Smooth muscle cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 59: Fibroblasts - Metabolism" "Cluster 30: Breast - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" FAIM2 "KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2" ENSG00000135472 "Fas apoptotic inhibitory molecule 2" Q9BWQ8 12 49866896-49904217 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 359.4;parathyroid gland: 98.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 118.5;Early spermatids: 246.7;Excitatory neurons: 76.5;Horizontal cells: 160.2;Inhibitory neurons: 102.5;Oligodendrocytes: 52.4" "Cancer enriched" "Detected in many" 8 "glioma: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.9" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 33.6" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018790, HPA048800" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "Intermediate filaments" "HPA018790: AB_1852822, HPA048800: AB_2680526" "unprognostic (1.74e-1)" "unprognostic (5.98e-4)" "unprognostic (2.22e-1)" "unprognostic (9.75e-3)" "unprognostic (3.36e-2)" "unprognostic (2.61e-4)" "unprognostic (2.62e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (1.75e-2)" "unprognostic (5.66e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-6)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.47e-1)" "unprognostic (6.78e-4)" FAM24B "AC073585.2, MGC45962" ENSG00000213185 "Family with sequence similarity 24 member B" Q8N5W8 10 122849078-122879641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0" "Group enriched" "Detected in many" 4 "Distal tubular cells: 84.0;Early spermatids: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Testis - Early spermatids" HPA052490 Supported "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "HPA052490: AB_2681851" "unprognostic (4.03e-2)" "unprognostic (4.27e-2)" "unprognostic (3.13e-3)" "unprognostic (8.40e-5)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (6.42e-7)" "unprognostic (2.99e-1)" "unprognostic (7.06e-3)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (9.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.81e-3)" FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.3" "Cell type enhanced" "Detected in some" "Astrocytes: 257.5;Excitatory neurons: 506.5;Inhibitory neurons: 145.0;Oligodendrocyte precursor cells: 84.7" "Cancer enriched" "Detected in single" 6 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 4700 "Cluster 65: Brain - Ion transport" "Cluster 56: Neurons - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Cell Junctions" "HPA026878: AB_1848430, HPA074824: " "unprognostic (5.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.76e-6)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-1)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-4)" "unprognostic (8.83e-2)" "unprognostic (7.72e-2)" "unprognostic (2.25e-1)" FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 642.8;Endometrial stromal cells: 621.5;Extravillous trophoblasts: 725.8;Fibroblasts: 1239.4;Syncytiotrophoblasts: 1320.1" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" FCAMR "CD351, FCA/MR, FKSG87" ENSG00000162897 "Fc fragment of IgA and IgM receptor" Q8WWV6 1 206957965-206970625 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 38.1;lymphoid tissue: 26.2" "Group enriched" "Detected in some" 14 "Distal tubular cells: 6.2;Proximal tubular cells: 24.2" "Group enriched" "Detected in some" 5 "liver cancer: 2.4;renal cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056505 Enhanced NA NA 5300000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "HPA056505: AB_2732604" "unprognostic (2.94e-1)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (2.92e-1)" "unprognostic (7.44e-2)" "unprognostic (4.55e-3)" "unprognostic (2.69e-3)" "unprognostic (1.08e-4)" "unprognostic (3.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Group enriched" "Detected in some" 5 "Hofbauer cells: 239.6;Kupffer cells: 107.6;Late spermatids: 61.2;Macrophages: 76.3" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cancer enriched" "Detected in single" 46 "Leukemia: 22.9" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 73.8;Kupffer cells: 33.9;Macrophages: 24.9;Microglial cells: 10.9;monocytes: 12.2" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Cancer enriched" "Detected in single" 14 "Leukemia: 7.3" "Adipose visceral - Macrophages, Kidney - Macrophages, Prostate - Macrophages" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Group enriched" "Detected in many" 6 "Hofbauer cells: 243.9;Kupffer cells: 232.2;Macrophages: 324.9;monocytes: 901.8;NK-cells: 607.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 46.8" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266599-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.7;gallbladder: 3.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Exocrine glandular cells: 4.3;Melanocytes: 1.7;Microglial cells: 1.8;Proximal tubular cells: 3.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.5" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.5;Intestinal goblet cells: 63.8;Leydig cells: 27.9;Peritubular cells: 29.2;Prostatic glandular cells: 34.8;Smooth muscle cells: 34.4;Thymic epithelial cells: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "breast cancer: 49.6;skin cancer: 25.9;thyroid cancer: 16.5" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 266.4;prostate: 76.0" "Group enriched" "Detected in many" 16 "Oligodendrocytes: 347.0;Prostatic glandular cells: 556.8" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "prostate cancer: 223.1;Rhabdoid: 170.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Prostate glandular cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 73: Prostatic glandular cells - Transcription" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" FOLR1 "FOLR, FRα" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 480.2;fallopian tube: 187.2;lung: 193.5;salivary gland: 219.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 392.0;Alveolar cells type 2: 262.4;Breast glandular cells: 225.7;Club cells: 188.5;Collecting duct cells: 257.9;Cytotrophoblasts: 473.3;Proximal tubular cells: 247.5;Syncytiotrophoblasts: 328.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 259.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 137.8;ovarian cancer: 122.5" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077030 Approved "Nuclear membrane" "Secreted to blood" NA NA 448000 140000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 30: Breast - Lactation" "Nuclear membrane" "HPA077030: " "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (6.55e-2)" "unprognostic (3.49e-2)" "unprognostic (7.67e-3)" "unprognostic (1.98e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.18e-2)" "unprognostic (8.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (2.69e-1)" FOXE3 "FKHL12, FREAC8" ENSG00000186790 "Forkhead box E3" Q13461 1 47416285-47418052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cataract, Disease variant, Peters anomaly" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "Spermatogonia: 2.5" "Group enriched" "Detected in some" 4 "cervical cancer: 0.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "testis cancer: 10.1" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 39: Non-specific - Unknown function" "Cluster 47: Spermatogonia - Spermatogenesis" "unprognostic (2.11e-1)" "unprognostic (1.31e-2)" "unprognostic (1.23e-3)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (6.24e-2)" "unprognostic (1.24e-2)" "unprognostic (8.21e-2)" "unprognostic (1.49e-1)" "unprognostic (2.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.04e-1)" "unprognostic (2.39e-7)" "unprognostic (2.41e-1)" "unprognostic (5.46e-2)" "unprognostic (3.60e-1)" FOXI1 "FKHL10, FREAC6" ENSG00000168269 "Forkhead box I1" Q12951 5 170105897-170109734 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 44.0;salivary gland: 11.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.2;Distal tubular cells: 34.2;Ionocytes: 23.2;Melanocytes: 5.2;Salivary duct cells: 16.2" "Group enriched" "Detected in many" 7 "breast cancer: 5.8;renal cancer: 23.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "breast cancer: 4.1;testis cancer: 2.1" "Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA071469 Enhanced Supported Nucleoli,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 56: Neurons - Neuronal signaling" "Cluster 16: Non-specific - RNA binding" Nucleoli Vesicles "HPA071469: AB_2686403" "unprognostic (3.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (2.48e-2)" "unprognostic (8.06e-2)" "unprognostic (7.47e-2)" "unprognostic (2.73e-1)" "unprognostic (1.52e-2)" "unprognostic (9.71e-3)" "unprognostic (4.88e-3)" "unprognostic (6.20e-2)" "unprognostic (1.34e-2)" "unprognostic (2.22e-1)" FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 64.2;Kupffer cells: 29.6;Langerhans cells: 301.0;Macrophages: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Cancer enriched" "Detected in some" 5 "Gastric cancer: 6.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.9;kidney: 2.7;smooth muscle: 2.2" "Cell type enriched" "Detected in single" 20 "Distal tubular cells: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in single" 86 "olfactory bulb: 21.3" HPA000886 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 16: Non-specific - RNA binding" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14422.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 30146.1;Hofbauer cells: 78770.7;Macrophages: 37797.2;Proximal tubular cells: 53657.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125209.0;monocytes: 102128.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 69: Macrophages - Innate immune response" Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 629.4;Hofbauer cells: 179.1;Proximal enterocytes: 746.5;Proximal tubular cells: 328.9" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" FUT5 FUC-TV ENSG00000130383 "Fucosyltransferase 5" Q11128 19 5865826-5870540 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" HPA046966 Uncertain NA NA "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 47: Spermatogonia - Spermatogenesis" "HPA046966: AB_2679879" "unprognostic (7.72e-2)" "unprognostic (3.59e-1)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" G6PC "G6PC1, G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit" P35575 17 42900797-42914438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 75.1;liver: 286.7" "Group enriched" "Detected in some" 8 "Hepatocytes: 233.9;Proximal enterocytes: 170.1" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "liver cancer: 2.5" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052324 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA052324: AB_2681790" "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favorable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favorable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 25.8;tongue: 11.3" "Cell type enriched" "Detected in some" 7 "Skeletal myocytes: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Ascending Loop of Henle cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 14: Bone cancer - Transcription" "Cluster 27: Skeletal myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132144-71713600 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.0;choroid plexus: 46.0;heart muscle: 43.5" "Group enriched" "Detected in many" 13 "Excitatory neurons: 370.3;Inhibitory neurons: 376.2" "Cancer enhanced" "Detected in many" "prostate cancer: 8.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 10.4;testis cancer: 14.1" "Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Uncertain "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 32: Neurons - Synaptic function" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: AB_1858787, HPA047986: " "unprognostic (2.79e-2)" "unprognostic (6.83e-2)" "unprognostic (5.54e-2)" "unprognostic (3.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (6.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.00e-1)" "prognostic favorable (4.60e-4)" "unprognostic (2.00e-1)" "unprognostic (4.73e-1)" "unprognostic (1.96e-2)" "unprognostic (9.63e-3)" "prognostic favorable (3.91e-4)" "unprognostic (1.92e-1)" "unprognostic (7.94e-3)" GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 806.1;Proximal tubular cells: 387.5;Skeletal myocytes: 960.0" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 17: RS4;11 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902826 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease variant, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;liver: 36.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 101.6;Hepatocytes: 85.5;monocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 11.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 12.7" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: Non-specific - Cilium assembly" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: AB_10602135" "unprognostic (3.77e-2)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (2.39e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.75e-1)" "unprognostic (3.97e-1)" "prognostic favorable (8.69e-4)" "prognostic favorable (1.41e-4)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (7.22e-3)" "unprognostic (1.76e-2)" "unprognostic (2.23e-1)" "prognostic favorable (6.67e-4)" GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 350.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 859.3;Hofbauer cells: 490.1;Proximal enterocytes: 617.2;Proximal tubular cells: 401.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 170000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 19: Macrophages - Innate immune response" Nucleoplasm "HPA046258: AB_10967205" "unprognostic (2.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (9.89e-3)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "prognostic favorable (5.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.67e-1)" "unprognostic (3.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.03e-3)" "unprognostic (9.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.55e-1)" GGACT A2LD1 ENSG00000134864 "Gamma-glutamylamine cyclotransferase" Q9BVM4 13 100530164-100589528 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "kidney: 75.5" "Group enriched" "Detected in many" 4 "Proximal tubular cells: 88.9;Spermatocytes: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065320 Enhanced NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "HPA065320: AB_2685466" "unprognostic (1.93e-1)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (1.30e-3)" "unprognostic (9.12e-3)" "unprognostic (1.64e-2)" "unprognostic (1.58e-2)" "unprognostic (2.07e-2)" "unprognostic (7.41e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-2)" "unprognostic (2.45e-1)" "unprognostic (1.95e-2)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Group enriched" "Detected in some" 4 "Distal enterocytes: 20.0;Ductal cells: 54.8;Exocrine glandular cells: 40.9;Proximal enterocytes: 50.7" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 112.1" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 100.9;liver: 335.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 130.9;Distal enterocytes: 63.9;Hepatocytes: 264.2;Paneth cells: 63.6;Proximal enterocytes: 119.6;Undifferentiated cells: 62.7" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 41.0;skin cancer: 81.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 10 "Hepatocytes: 155.3;Proximal enterocytes: 50.9;Proximal tubular cells: 120.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 275.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 187.0;Proximal enterocytes: 115.0;Proximal tubular cells: 78.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" GMNC GEMC1 ENSG00000205835 "Geminin coiled-coil domain containing" A6NCL1 3 190852737-190892429 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.8;fallopian tube: 8.1;liver: 4.1" "Group enriched" "Detected in some" 4 "Early spermatids: 20.1;Endometrial ciliated cells: 5.2;Hepatocytes: 5.9;Proximal tubular cells: 6.9" "Cancer enriched" "Detected in some" 5 "ovarian cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA043663 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 35: Bipolar cells - Visual perception" "HPA043663: AB_10959313" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (5.45e-2)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (2.22e-3)" "unprognostic (2.73e-2)" "unprognostic (2.55e-3)" GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.6;esophagus: 108.8" "Cell type enhanced" "Detected in many" "dendritic cells: 270.4;Hofbauer cells: 77.8;Langerhans cells: 207.1;monocytes: 82.4;Schwann cells: 96.0;Suprabasal keratinocytes: 96.2" "Group enriched" "Detected in all" 4 "cervical cancer: 39.9;head and neck cancer: 46.4;lung cancer: 17.3;pancreatic cancer: 11.9;urothelial cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.1" "Group enriched" "Detected in many" 4 "dendritic cells: 67.1;granulocytes: 19.4;monocytes: 29.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.6;Leukemia: 83.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "HPA043113: AB_10967343" "prognostic favorable (7.57e-5)" "unprognostic (6.06e-2)" "unprognostic (3.43e-1)" "prognostic favorable (2.01e-4)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (1.14e-2)" "unprognostic (5.38e-3)" "unprognostic (1.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (4.26e-6)" "unprognostic (1.04e-1)" "unprognostic (2.16e-3)" "unprognostic (2.36e-1)" "unprognostic (2.07e-1)" GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 83.4;stomach 1: 52.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 117.2;Inhibitory neurons: 127.9;Melanocytes: 268.2;Oligodendrocyte precursor cells: 124.7;Schwann cells: 245.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nuclear bodies, Cytosol" "HPA036159: AB_10671835, HPA057384: AB_2683424" "unprognostic (3.91e-2)" "unprognostic (7.93e-2)" "unprognostic (3.14e-2)" "unprognostic (4.11e-4)" "unprognostic (5.03e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (4.82e-2)" "unprognostic (2.59e-2)" "unprognostic (9.90e-2)" "unprognostic (1.82e-2)" "unprognostic (4.54e-2)" GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "granulocytes: 51.9;Hofbauer cells: 222.8;Kupffer cells: 61.6;Macrophages: 136.6;Microglial cells: 52.9" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Group enriched" "Detected in some" 7 "Adipocytes: 26.1;Endothelial cells: 33.3;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 2.4;prostate cancer: 1.3;Rhabdoid: 3.2;Sarcoma: 4.2;thyroid cancer: 4.0" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 193.3;Paneth cells: 64.5;Proximal enterocytes: 137.1;Proximal tubular cells: 153.1" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 461.9;Inhibitory neurons: 387.3;Oligodendrocyte precursor cells: 368.7" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;liver cancer: 6.3;thyroid cancer: 5.1" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 66: Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 156.3" "Cell type enriched" "Detected in some" 308 "Erythroid cells: 1211.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "Leukemia: 33.3" "Kidney - Proximal tubular cells, Liver - Erythroid cells, Lung - Neutrophil_1" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 15000000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: AB_1849827" "unprognostic (1.60e-1)" "unprognostic (2.47e-2)" GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in some" 19 "NK-cells: 568.5;T-cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cancer enriched" "Detected in single" 8 "lymphoma: 1.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 41 "NK-cells: 678.2;T-cells: 222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 229.3;Proximal enterocytes: 255.1;Proximal tubular cells: 137.9" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.3;liver cancer: 10.0" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 292.5;Hepatocytes: 314.6;Proximal enterocytes: 392.7;Proximal tubular cells: 252.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" HAPLN4 "BRAL2, KIAA1926" ENSG00000187664 "Hyaluronan and proteoglycan link protein 4" Q86UW8 19 19254756-19262804 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 107.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 15.8;Inhibitory neurons: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055856 Enhanced "Secreted in brain" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 6: BEWO - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA055856: AB_2682946" "unprognostic (3.36e-4)" HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 187.4;Kupffer cells: 178.4;Langerhans cells: 103.8;Macrophages: 142.2;monocytes: 256.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 5 "Leukemia: 21.9;lymphoma: 31.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" HDHD3 "C9orf158, MGC12904" ENSG00000119431 "Haloacid dehalogenase like hydrolase domain containing 3" Q9BSH5 9 113373419-113376999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 193.6;Paneth cells: 154.5;Proximal enterocytes: 254.0;Proximal tubular cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020427, HPA024158, HPA024585" Enhanced Enhanced Nucleoli,Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Nucleoli Vesicles "HPA020427: AB_1850561, HPA024158: AB_1850563, HPA024585: AB_1850565" "unprognostic (1.30e-1)" "prognostic favorable (2.72e-4)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (8.24e-3)" "unprognostic (1.57e-2)" "unprognostic (6.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (5.87e-2)" "prognostic favorable (3.54e-7)" "unprognostic (2.16e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-1)" "unprognostic (1.19e-3)" HELT "bHLHb44, HCM1228, HESL, MEGANE, Mgn" ENSG00000187821 "Helt bHLH transcription factor" A6NFD8 4 185018841-185020804 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "kidney: 1.5" "Group enriched" "Detected in some" 13 "Alveolar cells type 1: 2.1;Distal tubular cells: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036188, HPA036189" Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 16: Non-specific - RNA binding" "HPA036188: AB_10672237, HPA036189: AB_2674997" HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 75.6;Distal enterocytes: 133.8;Enteroendocrine cells: 49.6;Intestinal goblet cells: 105.9;Paneth cells: 68.8;Proximal enterocytes: 125.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 38.0;testis cancer: 68.6" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Group enriched" "Detected in many" 4 "Hepatocytes: 630.9;Proximal tubular cells: 426.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 45.4;liver cancer: 42.6" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 78.9;Cholangiocytes: 146.3;dendritic cells: 58.6;Ductal cells: 102.4;Endothelial cells: 71.3;Hepatocytes: 56.4;Hofbauer cells: 72.2;Kupffer cells: 55.1;monocytes: 56.7" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 68.0" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 275.5;Leydig cells: 144.8;Oligodendrocytes: 390.1;Theca cells: 130.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Rhabdoid: 111.4" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296490-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 129.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 26.9;Distal enterocytes: 134.5;Exocrine glandular cells: 42.8;Proximal enterocytes: 174.3" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.8;Rhabdoid: 14.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 50: Enterocytes - Absorption" "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 280.0;Proximal tubular cells: 352.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 12 "Early spermatids: 14.1;Hofbauer cells: 36.9;Kupffer cells: 37.9;Macrophages: 32.7;monocytes: 45.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cancer enhanced" "Detected in single" "Leukemia: 3.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 315.8;Hofbauer cells: 514.0;Kupffer cells: 245.0;Macrophages: 496.0;Syncytiotrophoblasts: 650.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 6: BEWO - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" HNF1A "HNF1, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 8.2;Hepatocytes: 14.5;Intestinal goblet cells: 12.9;Paneth cells: 16.2;Proximal enterocytes: 31.5;Proximal tubular cells: 14.4;Undifferentiated cells: 13.1" "Group enriched" "Detected in many" 4 "colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.9;liver cancer: 16.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm "CAB010430: AB_2116746, HPA035231: AB_2674528" "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in some" "Astrocytes: 38.6;Distal enterocytes: 45.6;Enteroendocrine cells: 27.6;Intestinal goblet cells: 37.9;Paneth cells: 48.7;Proximal enterocytes: 137.9;Undifferentiated cells: 29.3" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 5 "Hepatocytes: 378.7;Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "liver cancer: 21.4;prostate cancer: 58.4" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5433.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 401.6" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" NA NA 120000000000 28000000000 "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 1769.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 56.0;Proximal enterocytes: 89.1;Proximal tubular cells: 175.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 55: Non-specific - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: AB_2683716" "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 102 "Plasma cells: 446.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cancer enriched" "Detected in some" 274 "Myeloma: 305.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "dendritic cells: 473.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cancer enhanced" "Detected in many" "Leukemia: 20.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859117 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.5;kidney: 3.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.2;Collecting duct cells: 2.0;Horizontal cells: 1.9;Late spermatids: 1.6;Sertoli cells: 2.8;Spermatocytes: 6.3;Spermatogonia: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "medulla oblongata: 14.5;pons: 13.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Neuroblastoma: 7.2" "Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA025285 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" IQSEC3 "KIAA1110, MGC30156" ENSG00000120645 "IQ motif and Sec7 domain ArfGEF 3" Q9UPP2 12 66767-178455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 39.1" "Group enriched" "Detected in some" 8 "Bipolar cells: 39.3;Excitatory neurons: 80.5;Horizontal cells: 141.6;Inhibitory neurons: 74.5;Spermatocytes: 51.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.4" "Kidney - Proximal tubular cells, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039025 Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Cytosol" "HPA039025: AB_10672768" "unprognostic (2.73e-2)" "unprognostic (1.56e-2)" "unprognostic (1.26e-2)" "unprognostic (4.24e-3)" "unprognostic (4.32e-2)" "unprognostic (1.28e-1)" "unprognostic (4.44e-2)" "unprognostic (5.14e-2)" "unprognostic (3.91e-1)" "unprognostic (8.82e-3)" "unprognostic (2.83e-3)" "unprognostic (7.16e-2)" "unprognostic (2.28e-2)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-2)" "unprognostic (1.36e-2)" ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 447.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 54: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" JAKMIP2 "JAMIP2, KIAA0555" ENSG00000176049 "Janus kinase and microtubule interacting protein 2" Q96AA8 5 147585438-147782775 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Group enriched" "Detected in many" 7 "Astrocytes: 189.5;Excitatory neurons: 247.0;Horizontal cells: 64.1;Inhibitory neurons: 223.9;Oligodendrocyte precursor cells: 152.6;Oligodendrocytes: 187.4" "Cancer enriched" "Detected in some" 6 "glioma: 4.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;MAIT T-cell: 5.3;memory CD4 T-cell: 2.8;memory CD8 T-cell: 5.5;naive CD8 T-cell: 4.6;NK-cell: 7.0" "Group enriched" "Detected in many" 6 "NK-cells: 7.0;T-cells: 7.3" "Cancer enhanced" "Detected in many" "Bone cancer: 26.4" "Kidney - Podocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046929, HPA065023" Approved Supported "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus" "HPA046929: AB_2679867, HPA065023: AB_2685407" "unprognostic (3.69e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (3.58e-2)" "unprognostic (1.63e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.21e-4)" "unprognostic (1.28e-1)" "unprognostic (5.20e-8)" "unprognostic (1.54e-3)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.9;Hofbauer cells: 80.3;Horizontal cells: 80.8;Melanocytes: 95.8;monocytes: 203.1;NK-cells: 81.9" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 139.3;lymphoma: 102.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79863668-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.2" "Cell type enhanced" "Detected in some" "dendritic cells: 28.4;Excitatory neurons: 19.0;Extravillous trophoblasts: 9.6;Horizontal cells: 27.6;Inhibitory neurons: 30.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 10.3" HPA048628 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 37: Neurons - Neuronal signaling" "HPA048628: AB_2680466" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-1)" "unprognostic (1.99e-1)" "unprognostic (9.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (3.78e-1)" "unprognostic (3.61e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-5)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" KCNJ10 "Kir1.2, Kir4.1" ENSG00000177807 "Potassium inwardly rectifying channel subfamily J member 10" P78508 1 159998651-160070160 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 100.7;kidney: 28.0;retina: 36.7" "Group enriched" "Detected in some" 7 "Astrocytes: 90.1;Muller glia cells: 67.2;Oligodendrocyte precursor cells: 34.2;Oligodendrocytes: 88.5" "Cancer enriched" "Detected in some" 6 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.8" "Kidney - Ascending Loop of Henle cells, Liver - Kupffer cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078302 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "HPA078302: AB_2732378" "unprognostic (2.64e-2)" "unprognostic (3.54e-3)" "unprognostic (6.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (6.98e-4)" "unprognostic (1.96e-1)" "unprognostic (7.13e-2)" "unprognostic (3.43e-1)" "unprognostic (1.28e-3)" "unprognostic (5.80e-4)" "unprognostic (9.52e-2)" "unprognostic (2.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "unprognostic (6.70e-3)" KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.7;Cholangiocytes: 88.5;Early spermatids: 133.4;Late spermatids: 78.9;Proximal tubular cells: 200.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cancer enhanced" "Detected in many" "Bladder cancer: 21.6;head and neck cancer: 20.4" "Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 60: Proximal tubular cells - Absorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.7;Alveolar cells type 2: 19.4;Cardiomyocytes: 24.4;Hepatocytes: 23.0;Muller glia cells: 20.7;Sertoli cells: 74.6;Smooth muscle cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.9;liver cancer: 9.2;Neuroblastoma: 11.1" "Breast - Endothelial cells, Kidney - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031066 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 72: Smooth muscle cells - ECM organization" "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" KHDRBS2 "MGC26664, SLM-1, SLM1" ENSG00000112232 "KH RNA binding domain containing, signal transduction associated 2" Q5VWX1 6 61679961-62286225 "Predicted intracellular proteins" "mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;retina: 4.0;thyroid gland: 4.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1402.3;Inhibitory neurons: 704.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.6" "Region enhanced" "Detected in many" "cerebral cortex: 5.8" "Group enriched" "Detected in some" 13 "memory B-cell: 5.9;naive B-cell: 6.9;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 12 "B-cells: 6.9;dendritic cells: 1.9" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000500, HPA029392" Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA000500: AB_1079184, HPA029392: AB_10600816" "unprognostic (6.98e-2)" "unprognostic (1.21e-1)" "unprognostic (3.06e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-3)" "unprognostic (4.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.25e-4)" "unprognostic (1.45e-2)" "unprognostic (2.19e-5)" "unprognostic (5.52e-2)" "unprognostic (4.54e-2)" "unprognostic (6.24e-3)" "unprognostic (1.15e-1)" KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Group enriched" "Detected in some" 4 "Prostatic glandular cells: 41.0;Proximal tubular cells: 108.6" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;Kidney cancer: 2.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" KLHL3 KIAA1129 ENSG00000146021 "Kelch like family member 3" Q9UH77 5 137617500-137736089 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Excitatory neurons: 90.5;Inhibitory neurons: 54.8;Late spermatids: 73.3;Muller glia cells: 39.8;Oligodendrocytes: 62.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051291 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA051291: AB_2681423" "unprognostic (4.31e-2)" "unprognostic (5.31e-1)" "unprognostic (4.99e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.41e-1)" "unprognostic (6.39e-3)" "unprognostic (3.28e-1)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.71e-1)" "unprognostic (5.20e-3)" "unprognostic (1.50e-4)" KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 25.4;Breast myoepithelial cells: 17.2;Mucus glandular cells: 66.3;Oligodendrocytes: 83.0;Salivary duct cells: 23.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 633.4;Gallbladder cancer: 339.7" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 30: Breast - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 7 "NK-cells: 1508.8;T-cells: 767.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Group enriched" "Detected in some" 7 "NK-cells: 25.4;T-cells: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Group enriched" "Detected in some" 5 "NK-cells: 26.5;T-cells: 41.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Group enriched" "Detected in some" 11 "Leukemia: 10.3;lymphoma: 33.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Group enriched" "Detected in many" 4 "Spermatocytes: 319.1;Spermatogonia: 108.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 174.7;Ionocytes: 235.2;Langerhans cells: 296.6;monocytes: 242.4;Syncytiotrophoblasts: 205.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 118.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 59.7;Inhibitory neurons: 60.0;Rod photoreceptor cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 32: Neurons - Synaptic function" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" LACTB2 CGI-83 ENSG00000147592 "Lactamase beta 2" Q53H82 8 70635318-70669185 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.0" "Cell type enhanced" "Detected in all" "Early spermatids: 365.5;Proximal tubular cells: 321.6;Spermatocytes: 224.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044391, HPA053040" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 37000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "Nucleoplasm, Golgi apparatus" "HPA044391: AB_10965168, HPA053040: AB_2682022" "unprognostic (6.33e-3)" "unprognostic (3.13e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-2)" "unprognostic (1.82e-1)" "unprognostic (4.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.34e-1)" "unprognostic (8.10e-2)" "unprognostic (3.95e-1)" "unprognostic (7.73e-3)" "unprognostic (1.96e-1)" "prognostic favorable (5.60e-4)" "unprognostic (3.70e-1)" "unprognostic (7.49e-2)" "unprognostic (2.93e-1)" "unprognostic (5.93e-2)" LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 48.7" "Group enriched" "Detected in many" 5 "Leydig cells: 113.2;Peritubular cells: 366.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.9" "Kidney - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" NA NA 1100000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 152.1" "Cell type enriched" "Detected in single" 9 "Suprabasal keratinocytes: 2.4" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "head and neck cancer: 1.1" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" LCNL1 FLJ45224 ENSG00000214402 "Lipocalin like 1" Q6ZST4 9 136981904-136986410 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.4;testis: 1.6" "Cell type enhanced" "Detected in some" "Astrocytes: 69.0;dendritic cells: 64.6;Horizontal cells: 28.8;Leydig cells: 53.3;Muller glia cells: 27.1;Peritubular cells: 121.7" "Cancer enhanced" "Detected in some" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "unprognostic (1.39e-1)" "unprognostic (4.60e-3)" "unprognostic (1.08e-3)" "unprognostic (5.14e-2)" "unprognostic (3.39e-1)" "unprognostic (2.03e-5)" "unprognostic (6.46e-2)" "unprognostic (6.67e-2)" "unprognostic (7.79e-2)" "unprognostic (9.51e-2)" "unprognostic (2.16e-1)" "unprognostic (9.82e-2)" "unprognostic (1.34e-9)" "unprognostic (4.31e-2)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "unprognostic (1.93e-1)" LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 335.5;intestine: 198.0;kidney: 153.0;pancreas: 211.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 896.9;Distal enterocytes: 884.1;Langerhans cells: 1130.9;Proximal enterocytes: 2822.2;Proximal tubular cells: 1688.4" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 27 "classical monocyte: 1464.7;intermediate monocyte: 553.8;myeloid DC: 1207.2" "Group enriched" "Detected in all" 50 "dendritic cells: 1207.2;monocytes: 1464.7" "Cancer enhanced" "Detected in many" "Gastric cancer: 40.5;liver cancer: 21.2" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Exocrine glandular cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1278.0;Macrophages: 365.1;Syncytiotrophoblasts: 513.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 8 "Hofbauer cells: 52.7;Kupffer cells: 69.8;Macrophages: 41.6;monocytes: 102.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 20.2;Kupffer cells: 87.1;Macrophages: 29.8;monocytes: 21.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 54.2;Kupffer cells: 16.7;Macrophages: 75.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 52: Spermatids - Smell perception" "Cluster 69: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" LRRC19 FLJ21302 ENSG00000184434 "Leucine rich repeat containing 19" Q9H756 9 26993136-27005672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 36.2;kidney: 42.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.6;Distal enterocytes: 112.9;Enteroendocrine cells: 20.3;Intestinal goblet cells: 24.7;Paneth cells: 29.7;Proximal enterocytes: 70.2;Proximal tubular cells: 52.5" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.0;renal cancer: 5.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 190000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (6.30e-2)" "unprognostic (5.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.05e-2)" "unprognostic (1.85e-2)" "unprognostic (4.16e-2)" "unprognostic (9.21e-5)" "unprognostic (1.87e-2)" "unprognostic (4.48e-2)" "prognostic favorable (7.08e-8)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" LRRC4 NAG14 ENSG00000128594 "Leucine rich repeat containing 4" Q9HBW1 7 128027071-128032107 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5" "Cell type enhanced" "Detected in many" "Horizontal cells: 34.0;Inhibitory neurons: 22.1;Respiratory ciliated cells: 44.8;Rod photoreceptor cells: 47.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 38.5" "Immune cell enriched" "Detected in some" 5 "neutrophil: 13.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.4" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051100 Approved "Golgi apparatus" NA NA 2100000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" "Golgi apparatus" "HPA051100: AB_2797241" "unprognostic (7.98e-2)" "unprognostic (6.15e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.34e-3)" "unprognostic (3.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (3.23e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.98e-4)" "unprognostic (4.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (5.84e-3)" LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Group enriched" "Detected in many" 10 "Endometrial stromal cells: 990.9;Fibroblasts: 1398.8;Leydig cells: 414.2;Smooth muscle cells: 491.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 221.2" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Early spermatids: 37.7;Inhibitory neurons: 64.7;Late spermatids: 246.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 51: Late spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Cell type enhanced" "Detected in many" "Endothelial cells: 119.5;Hofbauer cells: 720.1;Macrophages: 208.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 69: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" MARCHF10 "FLJ35757, MARCH-X, MARCH10, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 137.6" "Group enriched" "Detected in some" 9 "Early spermatids: 364.2;Late spermatids: 1306.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8" "Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 6: Late spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 86.0;Microglial cells: 111.3;Spermatocytes: 71.8;Syncytiotrophoblasts: 88.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 61: Non-specific - Transcription" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 55.2;Hofbauer cells: 178.9;Kupffer cells: 84.2;Langerhans cells: 58.7;Macrophages: 285.7" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.3;head and neck cancer: 1.4;lymphoma: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 19: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 257.7;Schwann cells: 274.2;Theca cells: 310.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Fibroblasts: 596.9;Peritubular cells: 231.7;Smooth muscle cells: 172.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cancer enhanced" "Detected in many" "Bone cancer: 116.5;Neuroblastoma: 110.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.2;Rod photoreceptor cells: 960.5;Sertoli cells: 481.0;Smooth muscle cells: 480.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cancer enhanced" "Detected in all" "ovarian cancer: 380.6" "Kidney - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1600.2;Basal respiratory cells: 1213.4;Hepatocytes: 4707.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 5: Bronchus - Unknown function" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" MINAR2 KIAA1024L ENSG00000186367 "Membrane integral NOTCH2 associated receptor 2" P59773 5 129748094-129766732 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 22 "skeletal muscle: 35.9" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "prostate cancer: 1.7" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA013760 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" "HPA013760: AB_1852363" "unprognostic (1.77e-1)" "unprognostic (5.13e-1)" MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 223.5;Extravillous trophoblasts: 531.3;Fibroblasts: 756.3;Leydig cells: 338.9;Peritubular cells: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 849.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 64.2;smooth muscle: 78.6" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Basal squamous epithelial cells: 80.4;Early spermatids: 82.8;Endometrial stromal cells: 53.9;Excitatory neurons: 35.6;Oligodendrocyte precursor cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cancer enhanced" "Detected in many" "skin cancer: 64.5" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035740 Approved Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" Cytosol "HPA035740: AB_10610141" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (8.05e-2)" "unprognostic (9.87e-3)" "unprognostic (5.62e-2)" "prognostic favorable (7.09e-5)" "unprognostic (5.77e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.92e-2)" "unprognostic (6.24e-2)" "unprognostic (1.73e-2)" MRLN "Linc-RAM, LINC00948, M1, MLN, MUSER1" ENSG00000227877 Myoregulin P0DMT0 10 59736692-59756041 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "skeletal muscle: 269.3;tongue: 147.3" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 91.6;Respiratory ciliated cells: 26.9;Rod photoreceptor cells: 27.6;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enriched" "Detected in some" 4 "cerebellum: 4.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 11 "cerebellum: 21.6" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 47: Retina - Visual perception" "Cluster 27: Skeletal myocytes - Muscle contraction" "unprognostic (2.32e-2)" "unprognostic (1.52e-1)" "unprognostic (2.27e-1)" "unprognostic (4.54e-1)" "unprognostic (3.17e-3)" "unprognostic (9.77e-2)" "unprognostic (1.09e-2)" "unprognostic (8.49e-2)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (6.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "granulocytes: 20.6;Kupffer cells: 6.3;Macrophages: 15.8;monocytes: 5.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.8" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" HPA040075 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "dendritic cells: 427.6;Hofbauer cells: 531.2;Kupffer cells: 705.2;Langerhans cells: 553.8;Macrophages: 755.6;monocytes: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cancer enriched" "Detected in some" 11 "Leukemia: 17.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 4 "Hofbauer cells: 124.3;Kupffer cells: 81.6;Langerhans cells: 98.4;Macrophages: 193.1;monocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 19: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943293 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 307.9;Proximal tubular cells: 477.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1414.9;neutrophil: 3051.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 3051.8" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Neutrophil_2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153" "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" MTNR1A MEL-1A-R ENSG00000168412 "Melatonin receptor 1A" P48039 4 186533655-186555567 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;intestine: 1.2;kidney: 2.1;testis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (7.99e-2)" "unprognostic (2.27e-1)" "unprognostic (2.16e-1)" "unprognostic (3.67e-1)" "unprognostic (2.14e-1)" "unprognostic (9.88e-2)" "unprognostic (9.20e-2)" "unprognostic (8.81e-2)" MYH8 "MyHC-peri, MyHC-pn" ENSG00000133020 "Myosin heavy chain 8" P13535 17 10390322-10421950 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 15.9;lymphoid tissue: 10.7;skeletal muscle: 16.7;tongue: 10.0" "Cell type enriched" "Detected in some" 15 "Skeletal myocytes: 1332.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7;renal cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "Rhabdoid: 9.8" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB016527" Enhanced Uncertain "Focal adhesion sites" NA NA 53000000 "Cluster 59: Non-specific - Translation" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 27: Skeletal myocytes - Muscle contraction" "Focal adhesion sites" "CAB016527: AB_2147291, HPA001349: AB_1079437" "unprognostic (5.87e-2)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" "unprognostic (1.25e-2)" "unprognostic (2.29e-3)" "unprognostic (1.08e-1)" "unprognostic (5.02e-3)" "unprognostic (7.87e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 917.4;Peritubular cells: 716.6;Sertoli cells: 223.9;Smooth muscle cells: 552.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Brain cancer: 98.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750922 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 30.1;tongue: 72.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.7;Inhibitory neurons: 7.1;Microglial cells: 4.6;Oligodendrocyte precursor cells: 7.7;Skeletal myocytes: 8.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.9;Cholangiocytes: 26.9;Cytotrophoblasts: 55.8;Distal enterocytes: 41.6;Hepatocytes: 46.4;Paneth cells: 29.1;Proximal enterocytes: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358477-50365830 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 1075.5" "Group enriched" "Detected in many" 10 "Alveolar cells type 1: 1775.0;Alveolar cells type 2: 4574.4" "Cancer enriched" "Detected in many" 18 "lung cancer: 249.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 8.7" "Group enriched" "Detected in many" 7 "B-cells: 4.3;dendritic cells: 8.7" "Group enriched" "Detected in some" 4 "lung cancer: 14.2;lymphoma: 20.9;ovarian cancer: 43.6" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" NA NA 1500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 41: Alveolar cells - Lung function" "CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143" "unprognostic (5.36e-2)" "unprognostic (4.77e-2)" "unprognostic (1.64e-3)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (4.65e-2)" "unprognostic (1.02e-1)" "unprognostic (8.30e-3)" "unprognostic (2.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.76e-3)" "unprognostic (7.67e-3)" "prognostic favorable (1.21e-4)" "unprognostic (4.08e-4)" "unprognostic (3.29e-1)" "unprognostic (9.83e-3)" "unprognostic (7.26e-5)" NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in many" "Astrocytes: 122.7;Excitatory neurons: 45.4;Horizontal cells: 87.8;Inhibitory neurons: 36.8;Muller glia cells: 25.8" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Skin - Adipocytes (Skin), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 63: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 453.4;skin 1: 273.2;vagina: 181.7" "Cell type enriched" "Detected in many" 4 "Suprabasal keratinocytes: 134.7" "Group enriched" "Detected in many" 4 "cervical cancer: 42.8;head and neck cancer: 48.5;melanoma: 28.3;urothelial cancer: 33.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "breast cancer: 10.4;head and neck cancer: 10.8" "Kidney - Intercalated cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in some" "HPA052812, HPA077239" Approved Supported Cytosol NA NA 400000 "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 23: Langerhans cells - Immune response" Cytosol "HPA052812: AB_2681960, HPA077239: " "unprognostic (3.56e-3)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.59e-3)" "unprognostic (3.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.37e-3)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (2.04e-2)" "unprognostic (1.90e-1)" "unprognostic (6.37e-6)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-1)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.0;Alveolar cells type 2: 42.5;Bipolar cells: 64.3;Early spermatids: 157.2;Late spermatids: 266.5" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1939.5;Inhibitory neurons: 1226.2;Oligodendrocyte precursor cells: 695.6;Oligodendrocytes: 417.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 753.1;Oligodendrocyte precursor cells: 581.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" NKAIN4 "bA261N11.2, C20orf58, FAM77A" ENSG00000101198 "Sodium/potassium transporting ATPase interacting 4" Q8IVV8 20 63240784-63272694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 68.1;choroid plexus: 20.3;kidney: 52.2" "Cell type enriched" "Detected in some" 4 "Proximal tubular cells: 336.6" "Cancer enriched" "Detected in many" 6 "glioma: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 29.5;Uterine cancer: 16.5" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029876 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 60: Proximal tubular cells - Absorption" "HPA029876: AB_10602038" "unprognostic (1.26e-1)" "unprognostic (4.27e-1)" "unprognostic (6.07e-5)" "prognostic unfavorable (3.14e-4)" "unprognostic (6.65e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-3)" "unprognostic (1.94e-1)" "unprognostic (3.62e-2)" "unprognostic (2.69e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.44e-4)" "unprognostic (5.66e-2)" "unprognostic (6.74e-2)" "unprognostic (4.01e-1)" NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Cell type enriched" "Detected in many" 5 "NK-cells: 6101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 26 "Leukemia: 62.9;lymphoma: 64.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800529 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.1;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 31.4;Granulosa cells: 55.0;Proximal enterocytes: 12.7;Undifferentiated cells: 12.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.3;Uterine cancer: 2.8" "Kidney - Endothelial cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002014 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 47: Retina - Visual perception" "Cluster 17: Granulosa cells - Transcription regulation" "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 19.1;Early spermatids: 86.3;Endothelial cells: 25.7;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 153.0;Endothelial cells: 151.7;Serous glandular cells: 91.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.3;Gastric cancer: 10.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 248.1;Endothelial cells: 123.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" NPC1L1 SLC65A2 ENSG00000015520 "NPC1 like intracellular cholesterol transporter 1" Q9UHC9 7 44512535-44541330 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 54.2;liver: 48.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 33.9" "Group enriched" "Detected in many" 5 "liver cancer: 8.5;pancreatic cancer: 7.8;stomach cancer: 4.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 9.0;liver cancer: 7.8" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB070127, CAB070128" Enhanced NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 29: Hepatocytes - Metabolism" "CAB070127: AB_10002744, CAB070128: AB_10000815" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-3)" "unprognostic (8.43e-2)" "unprognostic (1.62e-1)" "unprognostic (2.07e-1)" "unprognostic (9.40e-2)" "unprognostic (6.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.96e-2)" "unprognostic (4.51e-2)" "unprognostic (7.59e-2)" "unprognostic (8.08e-10)" "unprognostic (1.64e-2)" "unprognostic (2.83e-1)" "unprognostic (3.62e-2)" "unprognostic (5.83e-2)" NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 164.8;Cytotrophoblasts: 120.1;Hofbauer cells: 425.7;Macrophages: 101.7;Microglial cells: 122.2;Proximal tubular cells: 106.6;Syncytiotrophoblasts: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 69: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 168.0;Alveolar cells type 2: 89.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 69.2" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 41: Alveolar cells - Lung function" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.2;Fibroblasts: 25.0;Inhibitory neurons: 18.3;Paneth cells: 21.8;Smooth muscle cells: 33.6" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Bone cancer: 61.4;breast cancer: 33.4" "Kidney - Fibroblasts, Skeletal muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 65: Breast cancer - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Excitatory neurons: 4.6;Inhibitory neurons: 3.4;Smooth muscle cells: 2.6;Spermatocytes: 2.5" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Bone cancer: 7.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 14: Bone cancer - Transcription" "Cluster 72: Smooth muscle cells - ECM organization" "unprognostic (4.63e-6)" "unprognostic (3.00e-1)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (3.74e-2)" "unprognostic (3.94e-2)" "unprognostic (5.40e-2)" "unprognostic (4.30e-2)" "unprognostic (3.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.94e-1)" NR2F1 "COUP-TFI, COUPTF1, EAR-3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1" ENSG00000175745 "Nuclear receptor subfamily 2 group F member 1" P10589 5 93583222-93594611 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 329.6;Fibroblasts: 116.4;Leydig cells: 110.4;Thymic epithelial cells: 174.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 85.9" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019281, HPA058974" Approved Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB019281: , HPA058974: AB_2732629" "unprognostic (8.07e-2)" "unprognostic (1.06e-2)" "unprognostic (3.86e-2)" "unprognostic (2.26e-1)" "unprognostic (4.75e-1)" "unprognostic (7.68e-3)" "unprognostic (3.18e-3)" "unprognostic (3.07e-2)" "unprognostic (2.21e-1)" "unprognostic (2.71e-3)" "unprognostic (5.24e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.28e-2)" "prognostic unfavorable (1.47e-4)" NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.7;Basal squamous epithelial cells: 48.6;Breast myoepithelial cells: 11.7;Peritubular cells: 11.0;Sertoli cells: 13.8;Smooth muscle cells: 18.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 25.4;granulocytes: 30.0;Horizontal cells: 18.6" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Group enriched" "Detected in some" 6 "Leukemia: 8.5;Neuroblastoma: 17.7" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 62: Granulocytes - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" "Vesicles, Cytosol" "CAB004606: AB_628397, CAB080140: , HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 11.2;intestine: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.3;Excitatory neurons: 1.5;Inhibitory neurons: 1.3;Kupffer cells: 5.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 7 "midbrain: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 14.1" "Kidney - Ascending Loop of Henle cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050299 Supported "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 35: Bipolar cells - Visual perception" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" NXF3 ENSG00000147206 "Nuclear RNA export factor 3" Q9H4D5 X 103075810-103093143 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 25.0;testis: 57.8" "Cell type enhanced" "Detected in some" "Early spermatids: 3.2;Endometrial ciliated cells: 8.8;Late spermatids: 2.7;Sertoli cells: 16.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 19.8;Sarcoma: 10.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Podocytes, Skeletal muscle - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003132, HPA046757" Approved Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 4: Platelets - Platelet activation" Nucleoplasm "HPA003132: AB_1079514, HPA046757: AB_2679789" "unprognostic (1.20e-3)" "unprognostic (6.72e-2)" "unprognostic (2.74e-1)" "unprognostic (3.05e-2)" "unprognostic (6.75e-4)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (8.86e-2)" "unprognostic (6.19e-2)" "unprognostic (3.13e-2)" "unprognostic (3.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.21e-10)" "unprognostic (1.90e-2)" "unprognostic (4.51e-2)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 14.1;Fibroblasts: 46.2;Leydig cells: 42.3;Peritubular cells: 39.0;Smooth muscle cells: 18.9;Thymic epithelial cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.2;Fibroblasts: 210.9;Leydig cells: 78.1;Smooth muscle cells: 69.8;Theca cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cancer enhanced" "Detected in many" "Bone cancer: 155.0;testis cancer: 143.3" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 76.3;Leydig cells: 131.8;Peritubular cells: 159.5;Rod photoreceptor cells: 44.5;Thymic epithelial cells: 47.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812142-28871267 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 4.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 11.6;Inhibitory neurons: 15.5" "Cancer enhanced" "Detected in single" "melanoma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9;skin cancer: 4.4" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070831 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "HPA070831: AB_2732167" "unprognostic (1.44e-1)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-3)" "unprognostic (6.28e-3)" "unprognostic (5.92e-2)" "unprognostic (1.82e-2)" "unprognostic (5.95e-3)" "unprognostic (4.28e-3)" "unprognostic (2.98e-1)" "unprognostic (1.52e-7)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-3)" OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 245.2;Extravillous trophoblasts: 167.5;Leydig cells: 816.0;Peritubular cells: 774.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_2, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" PACRG "FLJ32724, Glup, HAK005771, PARK2CRG" ENSG00000112530 "Parkin coregulated" Q96M98 6 162727132-163315492 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.7;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 289.5;Excitatory neurons: 122.4;Inhibitory neurons: 170.7;Late spermatids: 393.9;Respiratory ciliated cells: 110.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066293 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" "HPA066293: AB_2685652" "unprognostic (3.06e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (1.84e-1)" "unprognostic (6.26e-4)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.34e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (8.35e-2)" "unprognostic (2.93e-3)" PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 63.8;Distal enterocytes: 177.3;Intestinal goblet cells: 75.6;Oligodendrocytes: 110.5;Paneth cells: 71.8;Schwann cells: 58.8;Skeletal myocytes: 61.4" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cancer enhanced" "Detected in many" "breast cancer: 38.6" "Colon - Colon enterocytes, Heart muscle - Neutrophils, Kidney - Ascending Loop of Henle cells, Liver - Neutrophils, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 50: Enterocytes - Absorption" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.6;Early spermatids: 126.5;Hepatocytes: 74.8;Serous glandular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 190.6;Distal enterocytes: 284.3;Intestinal goblet cells: 102.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "Myeloma: 38.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 72: Smooth muscle cells - ECM organization" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Adipocytes: 58.0;Astrocytes: 74.6;Early spermatids: 76.5;Endothelial cells: 127.1;Excitatory neurons: 123.1;Inhibitory neurons: 66.3;Oligodendrocyte precursor cells: 184.8;Oligodendrocytes: 95.5;Spermatocytes: 59.7" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.5;Neuroblastoma: 5.7" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 68.2;Fibroblasts: 53.1;Leydig cells: 39.2;Peritubular cells: 57.2;Smooth muscle cells: 30.7;Theca cells: 19.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6;testis cancer: 38.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 508.7;Fibroblasts: 353.8;Leydig cells: 145.9;Smooth muscle cells: 366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 216.0;Neuroblastoma: 221.5;Sarcoma: 153.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.8;Extravillous trophoblasts: 68.6;Fibroblasts: 180.5;Syncytiotrophoblasts: 258.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Fibroblasts, Kidney - Podocytes, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1011.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 48.0" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Basal respiratory cells: 93.9;Muller glia cells: 80.7;Peritubular cells: 65.7;Thymic epithelial cells: 324.9" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 119.0;thyroid cancer: 95.0" "Breast - Fibroblasts, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Group enriched" "Detected in many" 4 "Adipocytes: 691.0;Endothelial cells: 633.9;monocytes: 238.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Leukemia: 40.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 667.8;skeletal muscle: 483.6;tongue: 412.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 311.2;Hepatocytes: 171.1;Proximal tubular cells: 289.1" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Enzymes" "Cluster 60: Proximal tubular cells - Absorption" "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favorable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 1638.0" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823, HPA053770" Supported Approved Vesicles "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" Vesicles "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532, HPA053770: AB_2682256" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 362.5;Fibroblasts: 403.1;Leydig cells: 881.4;Peritubular cells: 311.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 64.2" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Lipid metabolism" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.1;Exocrine glandular cells: 5.1;Gastric mucus-secreting cells: 4.8;Inhibitory neurons: 3.4;Proximal tubular cells: 3.7;Respiratory ciliated cells: 9.8" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" PNMA6A "MGC15827, PNMA6C" ENSG00000235961 "PNMA family member 6A" P0CW24 X 153072454-153075019 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.1;Horizontal cells: 57.0;Muller glia cells: 20.3;Proximal tubular cells: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "eosinophil: 2.0" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "HPA045007, HPA052115" Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 9: Neurons - Nervous system development" Mitochondria "HPA045007: AB_2679181, HPA052115: AB_2681734" "unprognostic (2.14e-2)" "unprognostic (2.35e-1)" "unprognostic (2.33e-2)" "unprognostic (4.12e-3)" "unprognostic (4.39e-2)" "unprognostic (3.44e-2)" "unprognostic (9.27e-3)" "unprognostic (2.15e-1)" "unprognostic (1.85e-1)" "unprognostic (2.46e-1)" "unprognostic (7.76e-4)" "unprognostic (5.75e-3)" "prognostic favorable (1.93e-5)" "unprognostic (4.61e-2)" "unprognostic (3.04e-1)" "unprognostic (4.04e-3)" "unprognostic (3.22e-2)" PPP1R14D "CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016" ENSG00000166143 "Protein phosphatase 1 regulatory inhibitor subunit 14D" Q9NXH3 15 40815451-40828709 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 111.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 274.5;Enteroendocrine cells: 98.8;Paneth cells: 193.1;Proximal enterocytes: 439.1;Undifferentiated cells: 72.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 6.2;colorectal cancer: 24.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA041846 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA041846: AB_10794307" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (5.91e-3)" "unprognostic (1.17e-2)" "unprognostic (4.68e-2)" "unprognostic (1.89e-1)" "unprognostic (7.74e-2)" "unprognostic (2.86e-1)" "unprognostic (5.26e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.55e-1)" "unprognostic (1.43e-2)" "unprognostic (3.74e-3)" "unprognostic (3.11e-2)" PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 62.9;Excitatory neurons: 117.7;Inhibitory neurons: 45.6;Oligodendrocyte precursor cells: 47.7;Oligodendrocytes: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Leukemia: 16.3;lymphoma: 37.0;Myeloma: 27.4;Neuroblastoma: 15.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 1135.4;liver: 675.2" "Cell type enriched" "Detected in some" 16 "Proximal enterocytes: 12421.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 75.9;Gastric cancer: 42.0;liver cancer: 32.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA038713, HPA052451" Supported "Secreted to digestive system" NA NA 210000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Fibroblasts: 257.0;Leydig cells: 98.4;Melanocytes: 323.9;Muller glia cells: 150.0;Peritubular cells: 202.9;Smooth muscle cells: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Brain cancer: 4.5;testis cancer: 5.2" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" PROX1 ENSG00000117707 "Prospero homeobox 1" Q92786 1 213983181-214041510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2;liver: 86.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 175.3;Cardiomyocytes: 128.9;Cholangiocytes: 119.3;Hepatocytes: 252.7;Horizontal cells: 163.4;Oligodendrocytes: 107.7;Paneth cells: 137.0" "Cancer enhanced" "Detected in many" "liver cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Ascending Loop of Henle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000842, HPA001030, HPA027298" Enhanced Nucleoplasm,Cytosol No No "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA000842: AB_2666112, HPA001030: AB_2666177, HPA027298: " "unprognostic (3.07e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (3.42e-1)" "unprognostic (7.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (3.29e-3)" "unprognostic (6.64e-2)" "unprognostic (4.56e-6)" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.71e-4)" "unprognostic (1.05e-1)" PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 706.5;Extravillous trophoblasts: 498.3;Muller glia cells: 490.5;Squamous epithelial cells: 477.4" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 148.5;Neuroblastoma: 67.4" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 4511.3;Inhibitory neurons: 1126.6;Oligodendrocyte precursor cells: 1120.6;Oligodendrocytes: 2974.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.1;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "Early spermatids: 13.3;Excitatory neurons: 11.0;Late spermatids: 4.3;Thymic epithelial cells: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.1;Gallbladder cancer: 6.3" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Alveolar cells type 1, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053245 Uncertain Approved Cytosol No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" PWWP3B "FLJ33516, MUM1L1" ENSG00000157502 "PWWP domain containing 3B" Q5H9M0 X 106168305-106208956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "ovary: 189.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 23.1;Endometrial stromal cells: 49.7;Leydig cells: 44.0;Peritubular cells: 69.4;Sertoli cells: 41.5;Thymic epithelial cells: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000168, HPA020464" Enhanced NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA000168: AB_1079431, HPA020464: AB_1854209" "unprognostic (2.79e-1)" "unprognostic (1.08e-2)" "unprognostic (3.83e-2)" "unprognostic (6.08e-2)" "unprognostic (5.06e-2)" "unprognostic (4.12e-6)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.86e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (8.43e-3)" "unprognostic (2.11e-5)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.53e-2)" PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 45.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 53.7;Early spermatids: 51.5;Excitatory neurons: 24.8;Inhibitory neurons: 67.6;Microglial cells: 16.4;Spermatocytes: 19.7" "Group enriched" "Detected in some" 4 "breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 1.3" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 68: Kidney - Mixed function" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavorable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 225.8;Hepatocytes: 630.6;Proximal enterocytes: 357.8;Proximal tubular cells: 258.3" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" PYGM GSD5 ENSG00000068976 "Glycogen phosphorylase, muscle associated" P11217 11 64746389-64759974 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 65 "skeletal muscle: 8468.3;tongue: 3594.2" "Cell type enriched" "Detected in many" 10 "Skeletal myocytes: 538.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 8.1" "Cancer enriched" "Detected in some" 10 "Rhabdoid: 23.9" "Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056003 Enhanced NA NA 10000000 "Cluster 10: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 27: Skeletal myocytes - Muscle contraction" "HPA056003: AB_2683006" "unprognostic (3.33e-1)" "unprognostic (6.03e-3)" "unprognostic (3.87e-4)" "unprognostic (1.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (2.92e-1)" "unprognostic (3.88e-1)" "unprognostic (3.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.64e-1)" "unprognostic (6.33e-6)" "unprognostic (3.37e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-2)" "unprognostic (5.68e-2)" PYHIN1 "IFIX, MGC23885" ENSG00000163564 "Pyrin and HIN domain family member 1" Q6K0P9 1 158930796-158977059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 23.1" "Group enriched" "Detected in some" 12 "NK-cells: 289.6;T-cells: 96.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "gdT-cell: 97.3;MAIT T-cell: 56.3;memory CD4 T-cell: 40.8;memory CD8 T-cell: 74.7;naive CD8 T-cell: 45.1;NK-cell: 36.8;T-reg: 67.3" "Group enriched" "Detected in many" 5 "NK-cells: 36.8;T-cells: 97.3" "Cancer enriched" "Detected in some" 5 "lymphoma: 13.8" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "HPA051224, HPA055373" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoli Nucleoplasm "HPA051224: AB_2681394, HPA055373: " "unprognostic (1.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.93e-3)" "unprognostic (2.64e-3)" "unprognostic (3.99e-2)" "unprognostic (3.57e-3)" "unprognostic (2.44e-3)" "unprognostic (2.10e-2)" "unprognostic (1.52e-1)" "unprognostic (1.47e-3)" "unprognostic (3.94e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-6)" "unprognostic (1.83e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-2)" "unprognostic (4.45e-3)" RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 332.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "NK-cells: 130.6;Proximal tubular cells: 185.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 93.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 28.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (other), Testis - Late spermatids" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 434.8;Inhibitory neurons: 407.0;Microglial cells: 138.6;Oligodendrocyte precursor cells: 290.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.1" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 37: Neurons - Neuronal signaling" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 65.1;Distal enterocytes: 80.1;Squamous epithelial cells: 102.3;Suprabasal keratinocytes: 122.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Kidney - Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.3;Endothelial cells: 92.4;Theca cells: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "cervical cancer: 22.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 79.2;Hofbauer cells: 173.9;Macrophages: 44.2;Melanocytes: 50.5;Proximal tubular cells: 167.8" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Group enriched" "Detected in many" 6 "Leukemia: 20.6;Myeloma: 22.9;skin cancer: 50.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 60: Proximal tubular cells - Absorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 93.1;dendritic cells: 46.5;Endothelial cells: 75.6;Hofbauer cells: 43.1;Kupffer cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 62: Granulocytes - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675671-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.7;Excitatory neurons: 29.7;Horizontal cells: 34.0;Inhibitory neurons: 26.5;Rod photoreceptor cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "HPA030359: AB_2673445, HPA030360: AB_2673446, HPA046593: AB_2679711" "prognostic favorable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32265832-32324659 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.0;heart muscle: 13.8;retina: 26.1" "Cell type enhanced" "Detected in some" "Astrocytes: 40.5;Cone photoreceptor cells: 19.0;Excitatory neurons: 46.2;Horizontal cells: 38.5;Oligodendrocyte precursor cells: 72.7;Rod photoreceptor cells: 35.7" "Cancer enriched" "Detected in some" 4 "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 38: Neurons - Neuronal signaling" "HPA059607: AB_2684081" "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Group enriched" "Detected in many" 5 "Squamous epithelial cells: 1909.7;Suprabasal keratinocytes: 4570.8" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 20.4;head and neck cancer: 42.3" "Kidney - Intercalated cells, Prostate - Urothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808067-61894247 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.3;choroid plexus: 62.3;kidney: 56.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 84.9;Proximal tubular cells: 141.1;Salivary duct cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favorable (1.13e-8)" "prognostic unfavorable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;choroid plexus: 10.8" "Group enriched" "Detected in some" 4 "Early spermatids: 84.5;Excitatory neurons: 90.1;Inhibitory neurons: 93.5;Oligodendrocyte precursor cells: 37.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bone cancer: 4.8;skin cancer: 3.9" "Colon - Colon enteroendocrine cells, Kidney - Macrophages, Liver - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" HPA035837 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 37: Neurons - Neuronal signaling" "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" RNF212B C14orf164 ENSG00000215277 "Ring finger protein 212B" A8MTL3 14 23185316-23273477 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 27.1" "Cell type enhanced" "Detected in some" "Early spermatids: 54.2;Proximal tubular cells: 19.0;Spermatocytes: 94.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053574 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053574: AB_2682195" "unprognostic (2.88e-1)" "unprognostic (2.17e-1)" "unprognostic (4.65e-1)" "unprognostic (8.54e-2)" "unprognostic (1.30e-1)" "unprognostic (4.79e-1)" "unprognostic (4.48e-2)" "unprognostic (2.98e-2)" "unprognostic (3.82e-1)" "unprognostic (1.83e-2)" "unprognostic (4.96e-3)" "unprognostic (4.45e-1)" "unprognostic (7.33e-5)" "unprognostic (9.60e-2)" "unprognostic (3.40e-1)" "unprognostic (7.56e-2)" "unprognostic (5.39e-3)" RNF224 ENSG00000233198 "Ring finger protein 224" P0DH78 9 137227502-137229640 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 3.4;pituitary gland: 5.8" "Cell type enhanced" "Detected in some" "Paneth cells: 1.2;Proximal tubular cells: 2.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA079078 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Golgi apparatus" "HPA079078: " "unprognostic (2.45e-1)" "unprognostic (2.34e-3)" "unprognostic (7.01e-4)" "unprognostic (6.04e-2)" "unprognostic (5.26e-2)" "unprognostic (1.70e-3)" "unprognostic (3.87e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-3)" "unprognostic (4.57e-2)" "unprognostic (5.24e-2)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "unprognostic (4.95e-2)" "unprognostic (1.27e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 148.2;Endothelial cells: 80.2;Rod photoreceptor cells: 80.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112454500-112457112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 11.6;Oligodendrocytes: 45.2" "Group enriched" "Detected in some" 8 "testis cancer: 1.4;thyroid cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: Liver - Metabolism" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: AB_2257414" "unprognostic (9.86e-2)" "unprognostic (2.04e-4)" "unprognostic (6.35e-2)" "unprognostic (5.33e-3)" RUNDC3B "RPIB9, RPIP9" ENSG00000105784 "RUN domain containing 3B" Q96NL0 7 87627548-87832296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.3;brain: 6.3;liver: 5.6" "Group enriched" "Detected in many" 6 "Excitatory neurons: 165.1;Inhibitory neurons: 167.0;Microglial cells: 105.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056968, HPA057155, HPA075760" Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 37: Neurons - Neuronal signaling" Cytosol Vesicles "HPA056968: AB_2683292, HPA057155: AB_2683353, HPA075760: " "unprognostic (2.49e-1)" "unprognostic (1.99e-1)" "unprognostic (2.12e-1)" "unprognostic (1.83e-1)" "unprognostic (2.20e-2)" "unprognostic (1.77e-3)" "unprognostic (1.19e-2)" "unprognostic (4.16e-2)" "unprognostic (2.56e-1)" "unprognostic (1.19e-1)" "unprognostic (9.42e-5)" "unprognostic (4.44e-1)" "prognostic favorable (2.62e-6)" "unprognostic (1.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.32e-1)" "unprognostic (9.55e-2)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 261.4;Endothelial cells: 153.5;NK-cells: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 21.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 112.3;Hofbauer cells: 65.6;Langerhans cells: 53.8;Oligodendrocyte precursor cells: 128.0;Schwann cells: 90.9;Sertoli cells: 74.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.9" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.8;retina: 75.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 75.1;Cone photoreceptor cells: 63.8;Excitatory neurons: 385.0;Inhibitory neurons: 138.0;Late spermatids: 48.2" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 12.7" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: AB_628099, HPA026685: AB_1856817, HPA063573: AB_2685045" "unprognostic (4.78e-2)" "unprognostic (3.24e-2)" "unprognostic (1.68e-2)" "unprognostic (5.05e-5)" "unprognostic (4.23e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (5.90e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-3)" "unprognostic (8.76e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.68e-12)" "unprognostic (2.65e-2)" "unprognostic (8.29e-2)" "unprognostic (2.25e-2)" "unprognostic (8.44e-2)" SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Astrocytes: 45.5;Excitatory neurons: 106.4;Inhibitory neurons: 157.5;Microglial cells: 160.5;Oligodendrocyte precursor cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.0;Endothelial cells: 75.3;Excitatory neurons: 27.9;Microglial cells: 42.9;Oligodendrocytes: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 53.6;Alveolar cells type 1: 21.8;Endothelial cells: 77.6;Late spermatids: 21.5;Microglial cells: 25.5;Spermatocytes: 27.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 320.3;Proximal tubular cells: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 49: Non-specific - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" SHOC1 "C9orf84, FLJ32779, MZIP2, Zip2" ENSG00000165181 "Shortage in chiasmata 1" Q5VXU9 9 111686173-111795008 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 17.1" "Cell type enhanced" "Detected in some" "Early spermatids: 128.9;Microglial cells: 24.6;Oligodendrocyte precursor cells: 31.8;Spermatocytes: 96.5" "Cancer enhanced" "Detected in some" "cervical cancer: 0.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 5.8" "Kidney - Intercalated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA032108 Approved Vesicles,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "Vesicles, Cytosol" "HPA032108: AB_10669884" "unprognostic (2.63e-1)" "unprognostic (1.83e-4)" "unprognostic (9.12e-2)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (9.05e-2)" "unprognostic (5.02e-2)" "unprognostic (6.22e-2)" "unprognostic (1.65e-1)" "unprognostic (8.14e-2)" "unprognostic (2.30e-1)" "unprognostic (8.33e-5)" "unprognostic (6.93e-2)" "unprognostic (2.84e-1)" "unprognostic (3.77e-1)" "unprognostic (7.31e-2)" SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 32.3;Kupffer cells: 75.6;Macrophages: 62.9;monocytes: 132.9;Schwann cells: 25.4" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Group enriched" "Detected in many" 7 "Leukemia: 9.9;lymphoma: 31.8" "Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 8.0;Kupffer cells: 17.3;Langerhans cells: 4.0;Macrophages: 11.8;Microglial cells: 13.7;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" SLC12A1 NKCC2 ENSG00000074803 "Solute carrier family 12 member 1" Q13621 15 48178438-48304078 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Bartter syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 878 "kidney: 705.6" "Group enriched" "Detected in some" 4 "Collecting duct cells: 33.5;Distal tubular cells: 93.3" "Cancer enriched" "Detected in single" 4 "renal cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014967, HPA018107" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 16: Non-specific - RNA binding" Vesicles Nucleoplasm "HPA014967: AB_1854503, HPA018107: AB_1854504" "unprognostic (3.52e-2)" "unprognostic (1.30e-2)" "unprognostic (9.65e-2)" "unprognostic (1.74e-2)" "unprognostic (7.77e-2)" "unprognostic (1.04e-1)" "unprognostic (8.72e-2)" "unprognostic (2.06e-1)" "unprognostic (9.85e-3)" "unprognostic (2.81e-4)" "unprognostic (9.75e-2)" "unprognostic (2.61e-1)" "unprognostic (5.47e-2)" "unprognostic (2.03e-1)" "unprognostic (5.20e-4)" "unprognostic (8.52e-2)" SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 57.1;Extravillous trophoblasts: 39.4;Proximal tubular cells: 156.1" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 33.2" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 151.3;kidney: 191.1" "Cell type enhanced" "Detected in many" "Astrocytes: 81.3;Distal enterocytes: 48.7;Proximal tubular cells: 177.8;Theca cells: 70.6" "Cancer enhanced" "Detected in many" "renal cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "Cell Junctions" "HPA049286: AB_2680699" "unprognostic (3.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-3)" "unprognostic (1.76e-2)" "unprognostic (5.96e-2)" "unprognostic (3.50e-3)" "unprognostic (5.01e-2)" "unprognostic (2.11e-3)" "unprognostic (5.99e-2)" "unprognostic (4.60e-2)" "prognostic favorable (2.56e-6)" "unprognostic (7.57e-3)" "unprognostic (1.27e-2)" "unprognostic (3.72e-1)" "unprognostic (1.94e-1)" SLC17A4 KIAA2138 ENSG00000146039 "Solute carrier family 17 member 4" Q9Y2C5 6 25754699-25781199 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "gallbladder: 16.3;intestine: 31.9;liver: 47.3;pancreas: 22.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 82.8;Distal enterocytes: 68.9;Hepatocytes: 34.3;Intestinal goblet cells: 20.1;Paneth cells: 37.0;Proximal enterocytes: 43.8" "Group enriched" "Detected in some" 6 "liver cancer: 11.0;renal cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 3.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "cerebellum: 1.5" HPA055564 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 50: Enterocytes - Absorption" "HPA055564: AB_2682852" "unprognostic (6.52e-2)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1681.2;Microglial cells: 323.8;Muller glia cells: 519.5;Oligodendrocyte precursor cells: 227.7;Oligodendrocytes: 235.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" SLC22A13 "OAT10, OCTL1, OCTL3, ORCTL3" ENSG00000172940 "Solute carrier family 22 member 13" Q9Y226 3 38265812-38278757 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "kidney: 9.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 4.5;Ionocytes: 3.0;Proximal tubular cells: 6.7;Sertoli cells: 2.8" "Cancer enriched" "Detected in single" 7 "renal cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035603, HPA035962" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 52: Spermatids - Smell perception" "Cluster 60: Proximal tubular cells - Absorption" "HPA035603: AB_10672869, HPA035962: AB_2674890" "unprognostic (2.73e-2)" "unprognostic (6.70e-2)" "unprognostic (2.80e-1)" "unprognostic (5.68e-2)" "unprognostic (7.13e-3)" "unprognostic (3.50e-3)" "unprognostic (6.83e-2)" "unprognostic (1.49e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-5)" "unprognostic (3.39e-1)" "unprognostic (1.96e-2)" "unprognostic (5.24e-2)" "unprognostic (2.74e-1)" SLC26A4 "DFNB4, PDS" ENSG00000091137 "Solute carrier family 26 member 4" O43511 7 107660828-107717809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "thyroid gland: 263.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.8;Inhibitory neurons: 53.0;Ionocytes: 48.6;Serous glandular cells: 24.9" "Cancer enriched" "Detected in some" 8 "thyroid cancer: 37.6" "Group enriched" "Detected in many" 88 "amygdala: 4.0;basal ganglia: 10.2;cerebral cortex: 11.8;hippocampal formation: 8.8" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 8 "B-cells: 1.0" "Cancer enriched" "Detected in some" 6 "lymphoma: 17.0" "Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in many" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "hippocampal formation: 4.8" HPA042860 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 37: Neurons - Neuronal signaling" "HPA042860: AB_10796680" "unprognostic (1.19e-2)" "unprognostic (4.84e-2)" "unprognostic (5.44e-2)" "unprognostic (8.44e-2)" "unprognostic (3.25e-2)" "unprognostic (3.26e-2)" "unprognostic (6.69e-2)" "unprognostic (1.85e-1)" "unprognostic (5.72e-2)" "unprognostic (9.58e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-2)" "unprognostic (1.39e-1)" SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 70.9;Microglial cells: 31.0;Paneth cells: 58.8;Proximal enterocytes: 192.4;Spermatocytes: 71.3" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in many" 8 "Leukemia: 43.7;lymphoma: 50.6;Myeloma: 31.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 61.8" "Cell type enriched" "Detected in some" 20 "Pancreatic endocrine cells: 142.6" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 5.5;Sarcoma: 17.7" "Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 4.1" HPA076165 Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 51: Myeloma - Humoral immune response" "Cluster 55: Endocrine cells - Hormone signaling" "HPA076165: AB_2732304" "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 69: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" SLC37A4 "G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d" ENSG00000137700 "Solute carrier family 37 member 4" 11 119024114-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 177.1;Hepatocytes: 154.0;Proximal enterocytes: 267.6;Proximal tubular cells: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" SLC45A1 DNB5 ENSG00000162426 "Solute carrier family 45 member 1" Q9Y2W3 1 8318114-8344167 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Symport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.4;Cone photoreceptor cells: 8.6;Excitatory neurons: 9.9;Horizontal cells: 13.5;Inhibitory neurons: 10.8" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 9.3" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078818 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "HPA078818: " "unprognostic (1.77e-3)" "unprognostic (1.37e-2)" "unprognostic (4.32e-3)" "unprognostic (8.32e-2)" "unprognostic (3.22e-3)" "unprognostic (1.56e-1)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (1.39e-3)" "unprognostic (3.18e-1)" "unprognostic (5.67e-2)" "unprognostic (8.53e-3)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (2.51e-3)" SLC4A1 "AE1, CD233, DI, EPB3, FR, RTA1A, SW, WD, WR" ENSG00000004939 "Solute carrier family 4 member 1 (Diego blood group)" P02730 17 44248390-44268141 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Blood group antigen" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 407.2" "Cell type enriched" "Detected in some" 289 "Erythroid cells: 900.9" "Cancer enriched" "Detected in single" 91 "renal cancer: 16.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.7" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 21 "Leukemia: 15.9" "Kidney - Intercalated cells, Liver - Erythroid cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015584, CAB034438, HPA063911" Enhanced NA NA 22000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "CAB034438: AB_2123479, HPA015584: AB_1844824, HPA063911: AB_2685151" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-2)" "unprognostic (2.32e-2)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (6.72e-3)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (1.93e-2)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (2.13e-1)" SLC51A OSTalpha ENSG00000163959 "Solute carrier family 51 subunit alpha" Q86UW1 3 196211487-196243178 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 64.5;liver: 71.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 55.5;Hepatocytes: 44.6;Leydig cells: 63.6;Peritubular cells: 104.3;Proximal enterocytes: 318.8;Sertoli cells: 63.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045488 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 50: Enterocytes - Absorption" "HPA045488: " "unprognostic (1.63e-2)" "unprognostic (1.27e-3)" "unprognostic (2.80e-1)" "unprognostic (7.66e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.54e-4)" "unprognostic (5.02e-2)" "unprognostic (1.07e-1)" "unprognostic (5.98e-3)" "unprognostic (5.41e-2)" "unprognostic (2.90e-2)" "unprognostic (2.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-5)" SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 75.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "liver cancer: 3.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 35: Liver cancer - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" SLC6A19 ENSG00000174358 "Solute carrier family 6 member 19" Q695T7 5 1201595-1225111 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "intestine: 142.4;kidney: 88.7" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 521.3" "Group enriched" "Detected in many" 4 "renal cancer: 7.9;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 5.8;liver cancer: 5.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037415, HPA043207" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA037415: AB_10672346, HPA043207: AB_2678363" "unprognostic (1.26e-1)" "unprognostic (1.01e-3)" "unprognostic (6.04e-2)" "unprognostic (3.64e-1)" "prognostic favorable (4.14e-6)" "unprognostic (1.37e-1)" "unprognostic (7.36e-2)" SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 331.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 99.1;Endometrial stromal cells: 73.6;Proximal tubular cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 9.3;eosinophil: 14.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 14.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 70: Basal prostatic cells - Lipid metabolism" "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 954.7;Excitatory neurons: 1248.3;Inhibitory neurons: 614.0;Microglial cells: 559.1;Oligodendrocyte precursor cells: 721.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Intercalated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 188.4;Hofbauer cells: 108.1;Kupffer cells: 79.1;Macrophages: 128.7;Microglial cells: 226.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 20.9;liver cancer: 20.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 69: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 199.3;Fibroblasts: 112.0;Smooth muscle cells: 101.1;Thymic epithelial cells: 48.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.3;testis: 42.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 82.3;Distal tubular cells: 87.1;Erythroid cells: 292.9;Proximal tubular cells: 225.9;Sertoli cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.5" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA069088 Enhanced NA NA 340000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" SMIM10L2A "LED, LINC00086, LINC0086, MGC39606, NCRNA00086" ENSG00000178947 "Small integral membrane protein 10 like 2A" P0DMW4 X 135421944-135428075 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "adrenal gland: 30.3;brain: 28.2;epididymis: 14.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 9.2;Horizontal cells: 6.4;Proximal tubular cells: 10.9;Theca cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "unprognostic (4.22e-2)" "unprognostic (4.72e-2)" "unprognostic (4.50e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (8.62e-3)" "unprognostic (5.83e-2)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (9.55e-3)" "unprognostic (1.36e-1)" "prognostic favorable (8.28e-8)" "unprognostic (5.29e-2)" "unprognostic (3.26e-1)" "unprognostic (7.37e-3)" "unprognostic (2.28e-2)" SMIM18 ENSG00000253457 "Small integral membrane protein 18" P0DKX4 8 30638580-30646064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.4;pituitary gland: 5.4;retina: 3.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.4;Excitatory neurons: 2.8;Horizontal cells: 7.7;Inhibitory neurons: 5.1;Microglial cells: 4.6;Oligodendrocyte precursor cells: 5.3;Proximal tubular cells: 3.5" "Cancer enriched" "Detected in single" 8 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.7" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066648 Supported Uncertain Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm Centrosome "HPA066648: AB_2685697" "unprognostic (2.19e-2)" "unprognostic (9.37e-2)" "unprognostic (3.31e-1)" "unprognostic (4.24e-2)" "unprognostic (1.66e-1)" "unprognostic (2.60e-1)" "unprognostic (7.29e-2)" "unprognostic (4.70e-1)" "unprognostic (8.91e-3)" "unprognostic (1.05e-1)" "unprognostic (2.36e-1)" "unprognostic (6.08e-2)" "unprognostic (4.01e-3)" "unprognostic (1.33e-1)" "unprognostic (3.25e-1)" "unprognostic (4.14e-1)" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1580.8;intestine: 753.9;kidney: 844.8" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 4278.4;Proximal tubular cells: 1491.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.7;pancreatic cancer: 37.4;renal cancer: 78.4;stomach cancer: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Gastric cancer: 34.8;Leukemia: 93.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm Cytosol "HPA045046: AB_10964444, HPA056027: AB_2683012" "unprognostic (2.18e-4)" "unprognostic (4.63e-1)" "unprognostic (5.68e-2)" "unprognostic (9.60e-2)" "unprognostic (1.93e-1)" "unprognostic (6.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.13e-10)" "unprognostic (1.68e-2)" "unprognostic (2.14e-1)" "unprognostic (8.36e-2)" "unprognostic (3.11e-2)" SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.1;kidney: 22.1;stomach 1: 33.1;testis: 26.1" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1360.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Group enriched" "Detected in many" 5 "Bile duct cancer: 7.9;colorectal cancer: 4.1;Gastric cancer: 9.6;Kidney cancer: 9.7;liver cancer: 6.1;lung cancer: 2.4;ovarian cancer: 3.9;pancreatic cancer: 6.7;Uterine cancer: 3.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "HPA065721: AB_2685546" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (7.07e-2)" "prognostic favorable (1.49e-4)" "unprognostic (3.42e-1)" "unprognostic (1.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (8.06e-2)" "prognostic favorable (4.09e-4)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.58e-2)" "prognostic favorable (1.64e-4)" SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 324.4;Peritubular cells: 769.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.3" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enhanced" "Detected in some" "Adipocytes: 38.2;Alveolar cells type 1: 6.7;Endothelial cells: 15.1;Sertoli cells: 5.5" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 10.9;Sarcoma: 4.3" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.5;skeletal muscle: 123.9;tongue: 69.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 65.0;Horizontal cells: 25.6;Inhibitory neurons: 31.4;Skeletal myocytes: 147.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 7.4;lung cancer: 7.5" "Kidney - Podocytes, Liver - Erythroid cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 7800000 "Cluster 80: Striated muscle - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 27: Skeletal myocytes - Muscle contraction" Cytosol "CAB015169: AB_2194363, CAB016232: AB_785785, HPA003394: AB_1080076, HPA003398: AB_1080074" "unprognostic (2.69e-1)" "unprognostic (4.72e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (2.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (2.18e-2)" SRARP "C1orf64, ERRF, MGC24047" ENSG00000183888 "Steroid receptor associated and regulated protein" Q8NEQ6 1 16004236-16008807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;breast: 5.1;choroid plexus: 6.2" "Cell type enriched" "Detected in some" 5 "Distal tubular cells: 121.3" "Group enriched" "Detected in some" 4 "breast cancer: 7.7;endometrial cancer: 2.2;prostate cancer: 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.8" "Cancer enriched" "Detected in some" 5 "breast cancer: 8.6" "Breast - Breast glandular cells, Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026676 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 65: Breast cancer - Unknown function" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm "HPA026676: AB_1853866" "unprognostic (8.55e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.68e-6)" "unprognostic (3.32e-2)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (8.25e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-3)" "unprognostic (6.32e-2)" STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 203.2;Hepatocytes: 108.9;Proximal enterocytes: 122.8;Proximal tubular cells: 185.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 71: Erythroid cells - Oxygen transport" Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" STRIT1 DWORF ENSG00000240045 "Small transmembrane regulator of ion transport 1" P0DN84 3 155290227-155293683 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "skeletal muscle: 1711.3;tongue: 698.4" "Cell type enriched" "Detected in some" 51 "Skeletal myocytes: 347.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;prostate cancer: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Low cancer specificity" "Detected in single" "Kidney - Proximal tubular cells" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: DU4475 - Unknown function" "Cluster 27: Skeletal myocytes - Muscle contraction" "unprognostic (6.77e-4)" "unprognostic (1.60e-2)" "unprognostic (6.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.82e-3)" "unprognostic (1.33e-2)" SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 191.4;Alveolar cells type 2: 137.1;Proximal enterocytes: 136.8" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 63.0" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatic stellate cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 65: Breast cancer - Unknown function" "Cluster 41: Alveolar cells - Lung function" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" SUSD3 MGC26847 ENSG00000157303 "Sushi domain containing 3" Q96L08 9 93058688-93085133 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.3;testis: 77.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.7;Hofbauer cells: 46.6;Proximal tubular cells: 42.1;Sertoli cells: 74.6;T-cells: 41.0;Theca cells: 65.9;Thymic epithelial cells: 62.2" "Cancer enhanced" "Detected in all" "breast cancer: 50.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "breast cancer: 24.9;Leukemia: 29.5;lymphoma: 46.8;Myeloma: 21.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042310 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA042310: AB_10796902" "prognostic favorable (5.13e-4)" "unprognostic (5.42e-2)" "unprognostic (3.65e-1)" "unprognostic (8.34e-3)" "unprognostic (9.06e-2)" "unprognostic (2.84e-2)" "unprognostic (2.94e-2)" "unprognostic (7.41e-3)" "unprognostic (5.06e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (3.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.39e-3)" "unprognostic (5.33e-2)" SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Group enriched" "Detected in many" 4 "Fibroblasts: 99.3;Inhibitory neurons: 49.1;Leydig cells: 43.0;Oligodendrocytes: 132.7;Syncytiotrophoblasts: 86.9;Theca cells: 34.8;Thymic epithelial cells: 98.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" TAF7L "CT40, TAF2Q" ENSG00000102387 "TATA-box binding protein associated factor 7 like" Q5H9L4 X 101268253-101293057 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 31.6" "Group enriched" "Detected in some" 5 "Early spermatids: 28.7;Late spermatids: 14.5;Spermatocytes: 42.9;Spermatogonia: 25.5" "Cancer enhanced" "Detected in some" "cervical cancer: 2.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 12.5;thyroid cancer: 5.0" "Kidney - Intercalated cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "HPA001879, HPA072008" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 39: Non-specific - Unknown function" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "HPA001879: AB_1857751, HPA072008: " "unprognostic (1.70e-2)" "prognostic favorable (8.71e-4)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (2.52e-2)" "unprognostic (4.97e-3)" "unprognostic (3.87e-3)" "unprognostic (1.72e-1)" "unprognostic (4.67e-3)" "unprognostic (2.16e-1)" "unprognostic (3.29e-1)" "unprognostic (1.36e-1)" "unprognostic (3.49e-3)" "unprognostic (6.76e-2)" "unprognostic (2.88e-1)" "unprognostic (5.97e-2)" "unprognostic (1.12e-2)" TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 105.7;monocytes: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 30: Breast - Lactation" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" TCL1B TML1 ENSG00000213231 "TCL1 family AKT coactivator B" O95988 14 95686426-95692628 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;lymphoid tissue: 2.5;testis: 2.5" "Cell type enriched" "Detected in single" 11 "Syncytiotrophoblasts: 9.5" "Cancer enriched" "Detected in single" 72 "testis cancer: 8.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 24 "naive B-cell: 11.7;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 24 "B-cells: 11.7;dendritic cells: 6.2" "Cancer enriched" "Detected in some" 4 "lymphoma: 78.4" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA053163 Uncertain Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Cytosol "HPA053163: AB_2682064" "unprognostic (1.55e-1)" TCTEX1D1 FLJ40873 ENSG00000152760 "Tctex1 domain containing 1" Q8N7M0 1 66752459-66779047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.9;liver: 7.1" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 56.3;granulocytes: 21.1;Inhibitory neurons: 21.1;Respiratory ciliated cells: 96.3" "Cancer enriched" "Detected in single" 10 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Leukemia: 3.8" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028420 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 56: Ciliated cells - Cilium assembly" "HPA028420: AB_10603995" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" "unprognostic (3.72e-4)" "unprognostic (1.22e-1)" "unprognostic (9.65e-3)" "unprognostic (1.81e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.53e-6)" "unprognostic (9.28e-4)" "unprognostic (2.78e-2)" "unprognostic (6.13e-3)" "unprognostic (3.65e-2)" TEX51 ENSG00000237524 "Testis expressed 51" A0A1B0GUA7 2 126898864-126902097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 183 "testis: 59.9" "Group enriched" "Detected in some" 23 "Early spermatids: 467.8;Late spermatids: 296.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 36: Spermatids - Spermatogenesis" TEX55 "C3orf30, FLJ32859, TSCPA" ENSG00000163424 "Testis expressed 55" Q96M34 3 119146151-119160042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 168 "testis: 53.8" "Group enriched" "Detected in some" 71 "Early spermatids: 386.7;Late spermatids: 461.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "HPA062468, HPA068480" Enhanced Approved Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA062468: AB_2684772, HPA068480: " "unprognostic (4.06e-3)" "unprognostic (3.67e-2)" "unprognostic (2.66e-1)" TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "dendritic cells: 23.3;Hofbauer cells: 48.3;Kupffer cells: 45.1;Macrophages: 71.6;Microglial cells: 58.4;Proximal tubular cells: 81.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Group enriched" "Detected in some" 14 "Leukemia: 13.1;lymphoma: 18.0;Rhabdoid: 6.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA050528, HPA063577" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm Cytosol "CAB032260: AB_2202845, HPA050528: , HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "pituitary gland: 106.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.9;Distal tubular cells: 6.2;Excitatory neurons: 7.2;Plasma cells: 6.6;Proximal tubular cells: 7.7;Sertoli cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 53: Non-specific - mRNA processing" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 325.4;Microglial cells: 240.8;Squamous epithelial cells: 111.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 126.1;Endothelial cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in many" 5 "Leukemia: 12.2;ovarian cancer: 22.4;Sarcoma: 24.1;thyroid cancer: 28.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 55.3;Macrophages: 25.3;monocytes: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1147.7;Ductal cells: 1249.3;Endothelial cells: 1190.6;Exocrine glandular cells: 1144.9;Glandular and luminal cells: 1929.9;Squamous epithelial cells: 951.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 14: Endometrium - Transcription regulation" "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 174.7;liver: 204.6" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 203.1;Hepatocytes: 240.2;Intestinal goblet cells: 193.7;Paneth cells: 254.8;Proximal enterocytes: 584.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 219.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 18.4;liver cancer: 39.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (4.44e-2)" "unprognostic (9.33e-2)" "unprognostic (3.57e-2)" "unprognostic (1.95e-1)" "unprognostic (5.21e-3)" TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 258.0" "Cell type enhanced" "Detected in all" "Late spermatids: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" TMEM106A MGC20235 ENSG00000184988 "Transmembrane protein 106A" Q96A25 17 43211835-43220041 "Predicted membrane proteins, Transporters" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 34.0;Granulosa cells: 45.4;Hofbauer cells: 42.7;Kupffer cells: 30.0;Langerhans cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 26.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 69: Macrophages - Innate immune response" "unprognostic (9.71e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (9.61e-5)" "unprognostic (4.95e-3)" "unprognostic (8.62e-2)" "unprognostic (1.79e-1)" "unprognostic (9.11e-2)" "unprognostic (1.76e-1)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (2.99e-2)" "unprognostic (6.08e-2)" "unprognostic (7.89e-3)" "unprognostic (1.39e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (8.30e-2)" TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 31.4;Late spermatids: 10.8;Microglial cells: 14.6;Peritubular cells: 25.2;Smooth muscle cells: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 29.9;thyroid cancer: 26.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "Early spermatids: 6.7;Excitatory neurons: 6.8;Late spermatids: 11.6;Oligodendrocyte precursor cells: 3.4;Prostatic glandular cells: 7.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.5;Neuroblastoma: 4.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Prostate - Prostate glandular cells, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 24: Spermatids - Unknown function" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.0;Horizontal cells: 9.0;Inhibitory neurons: 6.3;Oligodendrocyte precursor cells: 12.5;Proximal tubular cells: 11.7;Schwann cells: 3.5" "Cancer enriched" "Detected in some" 4 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.8;Sarcoma: 4.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 170000 "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: TE 441.T - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: AB_2686286" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-5)" "unprognostic (3.37e-1)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-3)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 60.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.7;Gastric cancer: 3.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" TMEM150C "FLJ12993, TTN3" ENSG00000249242 "Transmembrane protein 150C" B9EJG8 4 82483170-82562357 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 134.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 86.0;Granulosa cells: 101.1;Syncytiotrophoblasts: 114.7" "Cancer enhanced" "Detected in all" "breast cancer: 23.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 13.6" "Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052921 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 17: Granulosa cells - Transcription regulation" "HPA052921: AB_2681988" "unprognostic (2.99e-1)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.89e-3)" "unprognostic (1.71e-3)" "prognostic favorable (7.87e-4)" "unprognostic (2.94e-2)" "unprognostic (5.55e-2)" "unprognostic (1.06e-1)" "unprognostic (3.94e-2)" "prognostic favorable (5.68e-4)" "unprognostic (4.57e-2)" "prognostic favorable (4.59e-6)" "unprognostic (4.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 33.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 54.8;Enteroendocrine cells: 25.9;Intestinal goblet cells: 32.4;Paneth cells: 29.9;Proximal enterocytes: 92.6;Undifferentiated cells: 15.6" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045096 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 50: Enterocytes - Absorption" "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 60.9;Endothelial cells: 87.8;granulocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" TMEM52B "C12orf59, FLJ31166" ENSG00000165685 "Transmembrane protein 52B" Q4KMG9 12 10170542-10191801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "kidney: 175.8" "Cell type enriched" "Detected in some" 19 "Distal tubular cells: 827.2" "Cancer enriched" "Detected in some" 5 "renal cancer: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 15.7" "Kidney - Intercalated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA058096 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: BEWO - Unknown function" "Cluster 16: Non-specific - RNA binding" "Focal adhesion sites" "HPA058096: AB_2683603" "unprognostic (1.10e-2)" "unprognostic (7.61e-2)" "unprognostic (1.37e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (5.33e-3)" "unprognostic (1.37e-1)" "unprognostic (8.65e-2)" "unprognostic (7.14e-4)" "unprognostic (2.23e-1)" "unprognostic (6.36e-2)" "unprognostic (7.33e-2)" "unprognostic (3.24e-2)" "unprognostic (5.80e-2)" "unprognostic (5.51e-2)" "unprognostic (1.66e-1)" "unprognostic (3.18e-1)" TMEM72 "bA285G1.3, C10orf127, KSP37" ENSG00000187783 "Transmembrane protein 72" A0PK05 10 44911316-44937010 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 51.2;kidney: 74.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 25.6;Distal enterocytes: 26.8;Distal tubular cells: 24.9;Enteroendocrine cells: 6.6;Late spermatids: 16.6;Paneth cells: 11.6" "Cancer enriched" "Detected in some" 8 "renal cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 3.4" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039894, HPA062907" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 50: Enterocytes - Absorption" "HPA039894: AB_10795261, HPA062907: AB_2684900" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (8.58e-2)" "unprognostic (5.45e-2)" "prognostic favorable (1.01e-4)" "unprognostic (4.99e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" TMEM88 "FLJ20025, MGC71744" ENSG00000167874 "Transmembrane protein 88" Q6PEY1 17 7855066-7856099 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.5" "Group enriched" "Detected in many" 5 "Adipocytes: 176.0;Endothelial cells: 134.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Cancer enriched" "Detected in many" 6 "Rhabdoid: 57.5" "Colon - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052991 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "HPA052991: AB_2682006" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (3.44e-2)" "unprognostic (3.03e-1)" "unprognostic (6.49e-2)" "prognostic favorable (4.43e-6)" "unprognostic (1.98e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-3)" "unprognostic (9.04e-2)" "unprognostic (1.09e-2)" "unprognostic (2.68e-3)" "unprognostic (1.71e-1)" "unprognostic (7.56e-2)" "unprognostic (2.72e-1)" TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 140.5" "Group enriched" "Detected in some" 36 "Distal enterocytes: 151.0;Proximal enterocytes: 467.0" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Gastric cancer: 1.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Supported Mitochondria,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "Mitochondria, Cytosol" "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 32.3;Enteroendocrine cells: 22.2;Intestinal goblet cells: 25.8;Paneth cells: 39.7;Proximal enterocytes: 23.8;Serous glandular cells: 31.9;Undifferentiated cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 26: Intestinal epithelial cells - Absorption" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 205 "heart muscle: 10670.6" "Cell type enriched" "Detected in some" 56 "Cardiomyocytes: 1054.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 135.8;testis cancer: 61.2" "Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.8" "CAB015371, HPA015774, HPA017888" Enhanced Uncertain "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 57000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 77: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: AB_630390, HPA015774: AB_1858354, HPA017888: AB_1858355" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "unprognostic (2.33e-4)" "unprognostic (1.85e-1)" "unprognostic (7.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (8.63e-2)" "unprognostic (5.50e-3)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (9.98e-2)" TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155077 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 76.4;liver: 68.8;thyroid gland: 76.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 129.1;Proximal tubular cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA 39000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "HPA019851: AB_1858213, HPA062364: " "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favorable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in some" 7 "Hofbauer cells: 916.9" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;Leukemia: 2.4;testis cancer: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Sebaceous gland cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.6;Inhibitory neurons: 108.9;Microglial cells: 51.1;Oligodendrocyte precursor cells: 77.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: AB_2672381, HPA051273: AB_2681416, HPA059943: AB_2684173" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (2.39e-1)" "unprognostic (3.28e-3)" "unprognostic (6.64e-2)" "unprognostic (3.92e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-4)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (8.60e-2)" "unprognostic (5.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.78e-2)" TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 213.2;skeletal muscle: 580.7;tongue: 177.3" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 125.6;Skeletal myocytes: 213.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.1" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.7;liver cancer: 2.5" "Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" TRIM6 RNF89 ENSG00000121236 "Tripartite motif containing 6" Q9C030 11 5596109-5612958 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 20.9" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 73.1" "Cancer enhanced" "Detected in many" "testis cancer: 7.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 36.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA060514 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 60: Proximal tubular cells - Absorption" "HPA060514: AB_2684300" "unprognostic (9.00e-2)" "unprognostic (2.10e-3)" "unprognostic (9.16e-3)" "unprognostic (1.82e-1)" "unprognostic (3.25e-3)" "unprognostic (3.25e-3)" "unprognostic (2.35e-2)" "unprognostic (3.26e-3)" "unprognostic (8.59e-2)" "unprognostic (3.40e-2)" "unprognostic (8.61e-2)" "unprognostic (3.90e-1)" "unprognostic (5.68e-2)" "unprognostic (4.65e-4)" "unprognostic (4.77e-1)" "unprognostic (3.33e-2)" "unprognostic (4.36e-1)" TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051301-26068436 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1935.8" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 237.2;Skeletal myocytes: 514.7" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "skin cancer: 29.5" "Adipose subcutaneous - Mast cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 5.1" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" TRPC7 ENSG00000069018 "Transient receptor potential cation channel subfamily C member 7" Q9HCX4 5 136212745-136365545 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.3;Enteroendocrine cells: 3.5;Inhibitory neurons: 9.9;Proximal tubular cells: 5.4;Spermatocytes: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB022592, HPA031126" Uncertain NA NA "Cluster 41: Non-specific - Cilium assembly" "Cluster 32: Neurons - Synaptic function" "CAB022592: , HPA031126: AB_10603221" "unprognostic (1.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.03e-2)" "unprognostic (2.89e-5)" "unprognostic (3.26e-1)" "unprognostic (2.75e-1)" "unprognostic (9.99e-2)" "unprognostic (1.77e-1)" "unprognostic (6.78e-2)" TSPAN13 "NET-6, TM4SF13" ENSG00000106537 "Tetraspanin 13" O95857 7 16753755-16784536 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 299.3;Alveolar cells type 1: 434.3;Cytotrophoblasts: 294.0;dendritic cells: 375.9;Intestinal goblet cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 99.6;plasmacytoid DC: 231.7" "Group enriched" "Detected in many" 42 "B-cells: 99.6;dendritic cells: 231.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007426 Uncertain Uncertain Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "HPA007426: AB_10603137" "unprognostic (3.22e-1)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.56e-5)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (5.69e-2)" "unprognostic (6.63e-2)" "prognostic favorable (2.20e-4)" "unprognostic (1.50e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243481-43288258 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 20.7;pituitary gland: 9.2" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Bipolar cells: 6.4;Excitatory neurons: 11.9;Horizontal cells: 8.3;Inhibitory neurons: 12.7;Oligodendrocyte precursor cells: 11.6;Oligodendrocytes: 11.7" "Group enriched" "Detected in some" 4 "glioma: 3.0;liver cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 14.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA031735: AB_2674019, HPA031736: AB_10670294" "unprognostic (1.68e-1)" "unprognostic (7.88e-3)" "unprognostic (7.01e-2)" "unprognostic (1.62e-3)" "unprognostic (2.18e-1)" "unprognostic (2.24e-4)" "unprognostic (2.46e-3)" "unprognostic (3.01e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.01e-2)" "unprognostic (2.12e-4)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-3)" "unprognostic (3.04e-4)" TTLL6 FLJ35808 ENSG00000170703 "Tubulin tyrosine ligase like 6" Q8N841 17 48762235-48817214 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 18.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 177.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052397 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 14: Bone cancer - Transcription" "Cluster 6: Late spermatids - Spermatogenesis" Microtubules Vesicles "HPA052397: AB_2681812" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-1)" "unprognostic (8.04e-2)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.21e-5)" "unprognostic (1.10e-2)" "unprognostic (6.01e-5)" "unprognostic (1.17e-1)" "unprognostic (3.28e-1)" "unprognostic (6.68e-2)" "unprognostic (2.09e-3)" TTPA AVED ENSG00000137561 "Alpha tocopherol transfer protein" P49638 8 63048553-63086053 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 165.0" "Group enriched" "Detected in some" 4 "Astrocytes: 36.7;Hepatocytes: 76.0" "Cancer enriched" "Detected in some" 9 "liver cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" NA NA 10000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (7.82e-3)" "unprognostic (1.30e-7)" "unprognostic (1.78e-1)" "unprognostic (8.44e-2)" "unprognostic (1.25e-2)" "unprognostic (7.84e-2)" "unprognostic (4.04e-2)" "unprognostic (3.50e-1)" "unprognostic (5.40e-2)" "unprognostic (3.28e-1)" "unprognostic (1.14e-2)" "unprognostic (1.49e-2)" "unprognostic (3.57e-2)" "unprognostic (5.46e-3)" "unprognostic (6.16e-3)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 5212.6;Kupffer cells: 2893.4;Langerhans cells: 2460.5;Macrophages: 2602.8;monocytes: 3238.5;NK-cells: 1335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 53 "Leukemia: 105.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 94.7" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "liver cancer: 48.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;liver: 20.1;urinary bladder: 30.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.1;Paneth cells: 1.5;Proximal enterocytes: 1.0;Squamous epithelial cells: 1.1" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 8.7;Bladder cancer: 19.5;colorectal cancer: 7.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enhanced" "Detected in some" "Club cells: 1.1;Collecting duct cells: 2.0;Proximal tubular cells: 5.0" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lung cancer: 1.2;Myeloma: 1.4" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 31.4;kidney: 21.0;liver: 13.3;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 90.5;Distal enterocytes: 98.9;Enteroendocrine cells: 46.1;Hepatocytes: 51.7;Paneth cells: 58.7;Proximal enterocytes: 233.0;Proximal tubular cells: 114.4;Undifferentiated cells: 82.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045108 Supported NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: Liver cancer - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 124.1;Endometrial ciliated cells: 128.4;Glandular and luminal cells: 230.1;Hepatocytes: 515.3;Proximal tubular cells: 965.4" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 88.8;Uterine cancer: 39.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 25.8;Basal respiratory cells: 16.6;Exocrine glandular cells: 10.2;Late spermatids: 11.0;Squamous epithelial cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 11: Non-specific - Transcription" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 13.6;retina: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 98.9;Excitatory neurons: 425.8;Horizontal cells: 80.8;Inhibitory neurons: 346.7;Oligodendrocyte precursor cells: 278.2;Rod photoreceptor cells: 78.9" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.2;prostate cancer: 3.3" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Nuclear bodies" Vesicles "HPA042472: AB_10965318, HPA050959: " "unprognostic (7.91e-3)" "unprognostic (2.25e-4)" "unprognostic (1.44e-2)" "unprognostic (3.20e-4)" "unprognostic (1.92e-1)" "unprognostic (3.40e-2)" "unprognostic (3.31e-3)" "unprognostic (5.36e-2)" "unprognostic (5.16e-1)" "unprognostic (7.85e-2)" "unprognostic (5.24e-3)" "unprognostic (8.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.51e-2)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" "unprognostic (7.40e-3)" UNCX Uncx4.1 ENSG00000164853 "UNC homeobox" A6NJT0 7 1232872-1237326 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 17.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;Leukemia: 1.6" "Kidney - Ascending Loop of Henle cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.2" "Region enriched" "Detected in single" 8 "cerebellum: 7.5" HPA063294 Approved Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 47: Retina - Visual perception" Nucleoplasm "HPA063294: AB_2684977" "unprognostic (1.15e-1)" "unprognostic (9.71e-2)" VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 243.8;Langerhans cells: 275.3" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" VENTX "HPX42B, VENTX2" ENSG00000151650 "VENT homeobox" O95231 10 133237855-133241928 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Kupffer cells: 7.8;Langerhans cells: 10.8;Macrophages: 9.1;monocytes: 11.5" "Cancer enriched" "Detected in some" 15 "testis cancer: 30.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;granulocytes: 1.9;monocytes: 3.2" "Cancer enhanced" "Detected in some" "Leukemia: 1.8;testis cancer: 1.3" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" HPA050955 Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoli fibrillar center" "HPA050955: AB_2681288" "unprognostic (9.41e-2)" "unprognostic (8.89e-2)" "unprognostic (2.34e-1)" "unprognostic (4.26e-1)" "unprognostic (3.22e-2)" "unprognostic (2.01e-1)" "unprognostic (2.54e-1)" "unprognostic (9.62e-3)" "unprognostic (2.22e-1)" "unprognostic (3.00e-3)" "unprognostic (3.70e-4)" "unprognostic (4.22e-1)" "unprognostic (2.51e-3)" "unprognostic (3.43e-2)" "unprognostic (3.48e-1)" "unprognostic (7.54e-2)" "unprognostic (3.14e-1)" VSTM5 "C11orf90, LOC387804" ENSG00000214376 "V-set and transmembrane domain containing 5" A8MXK1 11 93818232-93850618 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.7;placenta: 4.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 21.4;Excitatory neurons: 5.1;Gastric mucus-secreting cells: 3.6;Inhibitory neurons: 9.0;Syncytiotrophoblasts: 4.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "prostate cancer: 4.8" "Kidney - Proximal tubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029525, HPA063591" Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 28: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA029525: AB_10600789, HPA063591: AB_2732704" "unprognostic (1.26e-1)" "unprognostic (4.48e-3)" "unprognostic (2.78e-1)" "unprognostic (1.54e-4)" "unprognostic (2.45e-2)" "unprognostic (9.91e-2)" "unprognostic (8.56e-2)" "unprognostic (1.37e-2)" "unprognostic (1.68e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.53e-2)" "unprognostic (2.37e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Early spermatids: 12.0;granulocytes: 1.6;Inhibitory neurons: 1.8;Late spermatids: 7.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 31.3;choroid plexus: 29.3;fallopian tube: 10.0" "Group enriched" "Detected in some" 11 "Astrocytes: 76.5;Endometrial ciliated cells: 38.5;Respiratory ciliated cells: 40.7" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cancer enriched" "Detected in single" 8 "Leukemia: 2.4" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.5" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" Cytosol "HPA036225: AB_10696652, HPA036226: AB_2675007" "unprognostic (1.68e-3)" "unprognostic (1.24e-3)" "unprognostic (2.48e-2)" "unprognostic (1.96e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (9.28e-3)" "unprognostic (1.34e-1)" "unprognostic (4.60e-9)" "unprognostic (1.79e-4)" "unprognostic (3.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.07e-1)" WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.5;Club cells: 20.5;Microglial cells: 19.2;Muller glia cells: 34.5;Prostatic glandular cells: 18.3;Salivary duct cells: 23.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 420.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Breast - Macrophages, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 59: Fibroblasts - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type palmitoyltransferase 6" Q9H6R6 10 112424428-112446917 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA014357: AB_2304658" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (6.24e-2)" "unprognostic (5.21e-1)" "unprognostic (3.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (9.30e-2)" "unprognostic (8.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.22e-2)"