Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1264.3;Cardiomyocytes: 398.0;Endothelial cells: 864.5;Hepatocytes: 661.1;Kupffer cells: 338.8;Microglial cells: 345.7;Smooth muscle cells: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;liver cancer: 139.1;skin cancer: 83.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: Liver cancer - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 184.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.4;Oligodendrocytes: 229.6;Schwann cells: 86.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Approved Uncertain Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.6;Fibroblasts: 123.0;Hepatocytes: 86.4;Inhibitory neurons: 76.1;Langerhans cells: 57.8;Microglial cells: 91.2;Schwann cells: 70.7;Theca cells: 55.3" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;lymphoma: 3.1;pancreatic cancer: 2.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 121.0;Syncytiotrophoblasts: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 19: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Cell type enhanced" "Detected in some" "Hepatocytes: 68.3;Paneth cells: 16.5;Proximal enterocytes: 34.4" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 265.7;Syncytiotrophoblasts: 488.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Kidney - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 19: Macrophages - Innate immune response" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" ABRACL "C6orf115, Costars, HSPC280, PRO2013" ENSG00000146386 "ABRA C-terminal like" Q9P1F3 6 139028745-139043302 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 370.9;Proximal tubular cells: 421.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030217 Enhanced Approved Nucleoplasm,Cytosol NA NA 9200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm Cytosol "HPA030217: AB_10602335" "unprognostic (1.10e-2)" "unprognostic (1.63e-1)" "unprognostic (9.30e-2)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.21e-1)" "unprognostic (8.17e-2)" "unprognostic (2.16e-1)" "unprognostic (3.07e-3)" "unprognostic (5.90e-3)" "unprognostic (3.63e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.65e-6)" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 348.6;Hepatocytes: 965.9;Proximal tubular cells: 592.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Skin - Sebaceous gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" ACAD11 FLJ12592 ENSG00000240303 "Acyl-CoA dehydrogenase family member 11" Q709F0 3 132558138-132660082 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 64.4;liver: 103.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 4.6;Plasma cells: 4.8;Syncytiotrophoblasts: 8.0" "Cancer enhanced" "Detected in single" "renal cancer: 1.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048317 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 61: Non-specific - Transcription" "HPA048317: AB_2680354" "unprognostic (5.04e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (3.31e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-4)" "unprognostic (1.20e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (5.90e-2)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (1.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.48e-1)" "unprognostic (2.71e-2)" "unprognostic (2.93e-1)" ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 10 "Late spermatids: 3052.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 84 "Leukemia: 30.1;lymphoma: 34.7;Myeloma: 16.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 51: Late spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 19.5;Gastric mucus-secreting cells: 73.3;Microglial cells: 25.5;Syncytiotrophoblasts: 12.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 176.4;Proximal tubular cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 60: Proximal tubular cells - Absorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 30.2;Proximal enterocytes: 19.5;Proximal tubular cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 12.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.3;Endometrial ciliated cells: 136.1;Glandular and luminal cells: 300.7;Proximal enterocytes: 467.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 89.6;colorectal cancer: 87.7" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 222.1;Basal prostatic cells: 74.8;Cone photoreceptor cells: 163.7;Excitatory neurons: 69.6;Inhibitory neurons: 108.2;Rod photoreceptor cells: 142.9" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - T-cells" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 125.5;Hepatocytes: 109.2;Intestinal goblet cells: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 29: Hepatocytes - Metabolism" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 100.1;Distal enterocytes: 126.4;Endothelial cells: 100.7;Extravillous trophoblasts: 44.3;Fibroblasts: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.9" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 24.8;Fibroblasts: 20.2;Leydig cells: 24.1;Microglial cells: 71.1;Peritubular cells: 17.9;Sertoli cells: 24.9;Theca cells: 57.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 67.8;testis cancer: 36.9" "Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 46: Non-specific - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 83.8;Excitatory neurons: 30.7;Inhibitory neurons: 89.1;Leydig cells: 48.2;Oligodendrocytes: 71.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.0" "Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 32: Neurons - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 83.5;Endothelial cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 348.1;Rod photoreceptor cells: 620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Endometrial stromal cells: 45.7;Endothelial cells: 22.7;Fibroblasts: 38.1;Leydig cells: 53.3;Microglial cells: 23.7;Muller glia cells: 26.7;Peritubular cells: 41.4;Smooth muscle cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 31.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Astrocytes: 11.1;Early spermatids: 6.0;Late spermatids: 30.3;Microglial cells: 5.5;Oligodendrocytes: 6.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2138.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 23.2" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 754.0;Hepatocytes: 4232.0;Thymic epithelial cells: 1166.4" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Endothelial cells" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 737.0;Hepatocytes: 1489.3;Proximal tubular cells: 1346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" ADRA2A "ADRA2, ADRA2R, ADRAR" ENSG00000150594 "Adrenoceptor alpha 2A" P08913 10 111077029-111080907 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 50.5;cervix: 46.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 67.4;Glandular and luminal cells: 31.9;Paneth cells: 130.0;Smooth muscle cells: 81.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 17.7" "Region enhanced" "Detected in all" "pons: 26.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.1" "Adipose visceral - Adipocytes (Visceral), Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 72: Smooth muscle cells - ECM organization" "unprognostic (3.87e-2)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "prognostic favorable (8.06e-4)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-1)" "unprognostic (4.64e-3)" "unprognostic (5.86e-2)" "unprognostic (5.63e-2)" "unprognostic (3.08e-6)" "unprognostic (1.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-3)" AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.5;Fibroblasts: 274.8;Leydig cells: 151.0;Melanocytes: 116.7;Peritubular cells: 489.4;Smooth muscle cells: 213.3;Thymic epithelial cells: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cancer enhanced" "Detected in many" "Leukemia: 59.9;skin cancer: 58.9" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 222.7;dendritic cells: 122.9;Excitatory neurons: 484.1;Inhibitory neurons: 293.5;Oligodendrocyte precursor cells: 202.6;Prostatic glandular cells: 143.4" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cancer enhanced" "Detected in many" "lymphoma: 22.4" "Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" AGAP2 CENTG1 ENSG00000135439 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Q99490 12 57723761-57742157 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 219.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 21.9;Horizontal cells: 21.1;Inhibitory neurons: 12.0;NK-cells: 21.7;Sertoli cells: 13.8;T-cells: 17.7" "Cancer enriched" "Detected in many" 12 "glioma: 20.6" "Region enhanced" "Detected in many" "cerebral cortex: 219.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023474, HPA075831" Enhanced Supported "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 72: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Midbody ring" "HPA023474: AB_1855378, HPA075831: " "unprognostic (1.87e-1)" "unprognostic (2.46e-3)" "unprognostic (9.26e-2)" "unprognostic (5.56e-4)" "unprognostic (3.95e-1)" "unprognostic (1.14e-2)" "unprognostic (5.00e-2)" "unprognostic (2.36e-2)" "unprognostic (3.39e-1)" "unprognostic (2.80e-1)" "unprognostic (1.93e-3)" "unprognostic (4.18e-1)" "unprognostic (4.81e-9)" "unprognostic (3.30e-1)" "unprognostic (2.72e-2)" "unprognostic (3.07e-1)" "unprognostic (5.75e-2)" AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol NA NA 5000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" AHCYL2 "IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 488.0;intestine: 177.4" "Cell type enhanced" "Detected in many" "Astrocytes: 549.8;Distal enterocytes: 229.9;Excitatory neurons: 129.3;Inhibitory neurons: 113.0;Oligodendrocyte precursor cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol NA NA 500000 "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 50: Enterocytes - Absorption" Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favorable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favorable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" AHRR "AHH, AHHR, bHLHe77, KIAA1234" ENSG00000063438 "Aryl-hydrocarbon receptor repressor" A9YTQ3 5 321759-438291 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 46.4" "Group enriched" "Detected in some" 15 "Early spermatids: 251.4;Late spermatids: 169.8;Spermatocytes: 97.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA021483 Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA021483: AB_1855110" "unprognostic (2.06e-4)" "unprognostic (3.48e-2)" "unprognostic (8.71e-3)" "unprognostic (2.23e-1)" "unprognostic (1.09e-1)" "unprognostic (9.33e-4)" "unprognostic (4.08e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.02e-5)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.65e-6)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.55e-2)" AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 834.6" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.0;colorectal cancer: 4.5;liver cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Hepatocytes: 550.1;Proximal tubular cells: 166.9;Serous glandular cells: 92.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 18.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 994.8;Proximal tubular cells: 653.6" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 123.2;Early spermatids: 43.0;Glandular and luminal cells: 50.2;Granulosa cells: 59.5;Spermatocytes: 52.8;Spermatogonia: 37.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 5.9;lymphoma: 12.9" "Kidney - Proximal tubular cells, Liver - Cholangiocyte, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" ANKRD33B ENSG00000164236 "Ankyrin repeat domain 33B" A6NCL7 5 10564070-10657816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.5;retina: 50.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 313.6;Excitatory neurons: 109.0;Rod photoreceptor cells: 81.8;Skeletal myocytes: 59.4" "Cancer enhanced" "Detected in many" "renal cancer: 7.4" "Region enhanced" "Detected in many" "hippocampal formation: 20.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 7.7;basal ganglia: 16.2;cerebral cortex: 19.6;hippocampal formation: 16.0;olfactory bulb: 10.0" HPA056974 Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 68: Kidney - Mixed function" "Cluster 44: Photoreceptor cells - Visual perception" Mitochondria "HPA056974: AB_2683295" "unprognostic (6.19e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-2)" "unprognostic (5.65e-3)" "unprognostic (2.84e-2)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.50e-3)" "unprognostic (4.41e-1)" "unprognostic (2.42e-3)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "prognostic favorable (4.16e-5)" "unprognostic (1.17e-1)" "unprognostic (4.80e-2)" "unprognostic (2.39e-2)" "unprognostic (5.47e-2)" ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 124.8;Breast myoepithelial cells: 72.3;Hepatocytes: 120.1;Late spermatids: 80.7;Serous glandular cells: 71.1;Smooth muscle cells: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 114.2;pancreatic cancer: 104.5" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 21: Serous glandular cells - Salivary secretion" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 126.5;Endometrial stromal cells: 83.0;Oligodendrocyte precursor cells: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 162.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 80.2;Schwann cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" AP003108.2 ENSG00000256591 "Novel transcript" 11 61429220-61485822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.6;Rod photoreceptor cells: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" HPA039732 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 61: Non-specific - Transcription" "HPA039732: AB_10962868" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (9.60e-2)" "unprognostic (4.91e-2)" "unprognostic (5.69e-2)" "unprognostic (5.98e-2)" "unprognostic (4.41e-2)" "unprognostic (6.40e-2)" "unprognostic (3.53e-2)" "unprognostic (5.83e-2)" "unprognostic (4.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-7)" "unprognostic (5.74e-2)" "unprognostic (9.69e-2)" "unprognostic (1.40e-1)" "unprognostic (4.66e-3)" AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 434.4;Kupffer cells: 369.1;Langerhans cells: 721.3;Macrophages: 351.2;monocytes: 557.3;Schwann cells: 370.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cancer enhanced" "Detected in all" "skin cancer: 169.9" "Breast - Endothelial cells, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" APBA2 "D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11L" ENSG00000034053 "Amyloid beta precursor protein binding family A member 2" Q99767 15 28884483-29118315 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Astrocytes: 51.6;Excitatory neurons: 140.7;Horizontal cells: 54.5;Inhibitory neurons: 103.8;NK-cells: 67.0;Oligodendrocyte precursor cells: 92.9;Oligodendrocytes: 70.0" "Cancer enhanced" "Detected in many" "glioma: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 5.4;naive CD8 T-cell: 5.6" "Lineage enriched" "Detected in many" 4 "T-cells: 5.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.3" "Adipose visceral - T-cells, Kidney - T-cells, Stomach - T-cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037065, HPA058796, HPA070376" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus" "CAB037065: AB_477178, HPA058796: , HPA070376: " "unprognostic (2.18e-1)" "unprognostic (9.20e-2)" "unprognostic (1.13e-1)" "unprognostic (6.16e-3)" "unprognostic (2.42e-1)" "unprognostic (5.96e-2)" "unprognostic (1.41e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-1)" "unprognostic (8.19e-2)" "unprognostic (4.71e-2)" "unprognostic (9.25e-2)" "unprognostic (4.21e-5)" "unprognostic (1.98e-2)" "unprognostic (4.74e-2)" "unprognostic (7.63e-3)" "unprognostic (4.28e-1)" APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 3.9;Cytotrophoblasts: 6.8;Hofbauer cells: 4.2;NK-cells: 8.3;Sertoli cells: 5.5;T-cells: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Group enriched" "Detected in some" 5 "Leukemia: 6.6;lymphoma: 7.8;Myeloma: 5.3" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Sertoli cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 88653.4" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 42.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 7945.2" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 48 "liver cancer: 169.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 108.5;Endometrial ciliated cells: 115.5;Glandular and luminal cells: 222.6;Hepatocytes: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 337.3" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" APOM "G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 390.7" "Group enriched" "Detected in many" 7 "Hepatocytes: 711.7;Proximal tubular cells: 406.4" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "liver cancer: 7.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 7400000000 8200000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 230.0;Excitatory neurons: 603.2;Inhibitory neurons: 255.6;Late spermatids: 214.1;Microglial cells: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 80.3;Early spermatids: 119.5;Hofbauer cells: 50.7;NK-cells: 176.8;Spermatocytes: 78.1;T-cells: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 35.3;lymphoma: 19.9;Myeloma: 14.7" "Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" ARHGEF3 "DKFZP434F2429, GEF3, STA3, XPLN" ENSG00000163947 "Rho guanine nucleotide exchange factor 3" Q9NR81 3 56727418-57079329 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 155.7;NK-cells: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034715, HPA064945" Uncertain Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA034715: AB_10600780, HPA064945: AB_2685389" "unprognostic (1.84e-2)" "unprognostic (2.22e-2)" "unprognostic (1.62e-2)" "prognostic favorable (2.17e-4)" "unprognostic (8.25e-2)" "prognostic favorable (2.61e-4)" "unprognostic (9.42e-2)" "unprognostic (3.83e-2)" "unprognostic (9.67e-2)" "unprognostic (7.44e-2)" "unprognostic (6.90e-2)" "unprognostic (4.99e-2)" "prognostic favorable (1.96e-7)" "unprognostic (8.24e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-2)" ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 15.4;Hofbauer cells: 33.4;Kupffer cells: 19.2;Macrophages: 21.5;monocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Leukemia: 12.2;lymphoma: 8.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 19: Macrophages - Innate immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" ARRDC3 "KIAA1376, TLIMP" ENSG00000113369 "Arrestin domain containing 3" Q96B67 5 91368631-91383317 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 396.3;Syncytiotrophoblasts: 347.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (2.28e-1)" "unprognostic (2.24e-1)" "unprognostic (9.42e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-3)" "unprognostic (4.91e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.25e-8)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.34e-1)" "unprognostic (5.74e-2)" "unprognostic (2.15e-1)" ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 396.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.0;Hepatocytes: 514.1;Proximal enterocytes: 271.8;Proximal tubular cells: 223.4" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085686-104115582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.4;liver: 151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.9;Distal enterocytes: 25.5;Granulosa cells: 65.4;Hepatocytes: 76.4;Proximal tubular cells: 45.5;Suprabasal keratinocytes: 64.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA069761 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA069761: AB_2686191" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in some" "Early spermatids: 58.2;Endometrial ciliated cells: 28.6;Late spermatids: 27.0;Respiratory ciliated cells: 23.9;Syncytiotrophoblasts: 149.8" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 136.7;Inhibitory neurons: 93.3;Oligodendrocyte precursor cells: 78.0;Oligodendrocytes: 129.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 22.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.3" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "HPA027550: AB_10600983" "unprognostic (2.06e-2)" "unprognostic (7.57e-3)" "unprognostic (1.82e-1)" "unprognostic (7.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (1.23e-2)" ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.5;Cardiomyocytes: 30.7;Excitatory neurons: 61.7;Inhibitory neurons: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (3.31e-2)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "unprognostic (6.17e-3)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.91e-1)" "unprognostic (3.28e-3)" "unprognostic (6.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.26e-1)" "unprognostic (5.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 11.3;Peritubular cells: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 192.0;Excitatory neurons: 129.4;Inhibitory neurons: 60.8;Muller glia cells: 116.7;Oligodendrocyte precursor cells: 120.3" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 119.1;pancreas: 271.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 155.1;Late spermatids: 358.4;Oligodendrocytes: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 51: Late spermatids - Spermatogenesis" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810024-24949101 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis, Lipid metabolism" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 58.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 171.6;Langerhans cells: 333.1;Late spermatids: 354.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 19.0;glioma: 10.7;lung cancer: 7.2;ovarian cancer: 24.0;testis cancer: 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 17.1" "Group enriched" "Detected in many" 10 "dendritic cells: 5.8;monocytes: 17.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain NA NA 97000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 36: Spermatids - Spermatogenesis" "HPA048592: AB_2680454" "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.38e-4)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavorable (8.54e-4)" BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 525.1" "Group enriched" "Detected in many" 7 "Hepatocytes: 511.9;Oligodendrocyte precursor cells: 201.2;Thymic epithelial cells: 172.6" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 9400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.8;Basal squamous epithelial cells: 90.5;Inhibitory neurons: 103.1;NK-cells: 137.8;Suprabasal keratinocytes: 77.0;T-cells: 295.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "Bone cancer: 18.1;Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" BCL7C ENSG00000099385 "BAF chromatin remodeling complex subunit BCL7C" Q8WUZ0 16 30833626-30894302 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018676, HPA052654" Uncertain Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: Non-specific - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA018676: AB_1845322, HPA052654: AB_2681903" "unprognostic (2.27e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (1.21e-1)" "unprognostic (3.60e-1)" "unprognostic (3.18e-3)" "unprognostic (4.91e-3)" "unprognostic (2.44e-1)" "unprognostic (3.41e-2)" "unprognostic (3.84e-2)" "unprognostic (9.22e-2)" "unprognostic (2.05e-2)" "unprognostic (2.45e-1)" "unprognostic (2.97e-1)" "unprognostic (2.07e-2)" "unprognostic (2.85e-1)" BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 223.9;Proximal enterocytes: 189.8;Proximal tubular cells: 777.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.4;Basal squamous epithelial cells: 30.2;Squamous epithelial cells: 20.6;Suprabasal keratinocytes: 23.5;Thymic epithelial cells: 25.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.6" "Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 16.3;Ionocytes: 16.5;Langerhans cells: 19.2;Squamous epithelial cells: 15.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 261.7;Pancreatic endocrine cells: 163.2;Peritubular cells: 661.5;Sertoli cells: 516.9;Smooth muscle cells: 422.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 153.9;thyroid cancer: 160.9" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 203.2;Skeletal myocytes: 761.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 7: NK-cells - Immune response regulation" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" BIN2 BRAP-1 ENSG00000110934 "Bridging integrator 2" Q9UBW5 12 51281038-51324668 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 101.3;lymphoid tissue: 48.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.1;Extravillous trophoblasts: 199.7;monocytes: 168.6;NK-cells: 422.6;Syncytiotrophoblasts: 146.9;T-cells: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 51.4;Myeloma: 46.7" "Kidney - T-cells, Lung - Neutrophil_2, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038666, HPA038667" Enhanced Enhanced "Plasma membrane" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA038666: AB_2676139, HPA038667: AB_2676140" "unprognostic (8.44e-3)" "prognostic favorable (1.33e-4)" "unprognostic (2.48e-1)" "prognostic favorable (6.34e-4)" "unprognostic (4.63e-1)" "unprognostic (2.00e-3)" "unprognostic (1.21e-1)" "unprognostic (3.59e-2)" "unprognostic (3.72e-2)" "unprognostic (7.47e-2)" "unprognostic (5.71e-2)" "unprognostic (3.29e-1)" "unprognostic (1.65e-3)" "unprognostic (4.03e-1)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-1)" BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 43.5;Endothelial cells: 21.5;Inhibitory neurons: 22.1;Microglial cells: 72.1;Plasma cells: 19.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "cervical cancer: 32.0;Myeloma: 43.5;Rhabdoid: 29.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Uncertain Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal keratinocytes: 48.3;Basal squamous epithelial cells: 42.3;Cytotrophoblasts: 139.0;Oligodendrocyte precursor cells: 71.2;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 55.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 138.2;Inhibitory neurons: 78.2;Oligodendrocyte precursor cells: 117.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 63: Astrocytes - Nervous system maintenance" Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 141.8;pituitary gland: 53.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.9;Excitatory neurons: 29.7;Horizontal cells: 35.9;Inhibitory neurons: 26.9;Oligodendrocyte precursor cells: 16.4;Oligodendrocytes: 27.7;Proximal enterocytes: 21.5" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 44.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.1;Kupffer cells: 21.8;Langerhans cells: 19.5;monocytes: 54.7;NK-cells: 37.9;T-cells: 15.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 9 "Leukemia: 24.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" C11orf95 MGC3032 ENSG00000188070 "Chromosome 11 open reading frame 95" C9JLR9 11 63759892-63768775 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045002 Approved "Intermediate filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Intermediate filaments" "HPA045002: AB_2679179" "unprognostic (4.23e-3)" "unprognostic (7.24e-3)" "unprognostic (6.47e-2)" "unprognostic (9.01e-3)" "unprognostic (7.54e-2)" "unprognostic (3.89e-1)" "unprognostic (8.94e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" "unprognostic (8.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.52e-3)" "unprognostic (1.85e-2)" "unprognostic (6.60e-2)" "unprognostic (5.68e-2)" "unprognostic (1.31e-3)" C12orf56 ENSG00000185306 "Chromosome 12 open reading frame 56" Q8IXR9 12 64264762-64390758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 6.6;testis: 7.5" "Cell type enhanced" "Detected in some" "Early spermatids: 54.2;Late spermatids: 43.7;Oligodendrocytes: 12.8;Proximal tubular cells: 11.3;Spermatocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;thyroid cancer: 1.4" "Kidney - Podocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA056986 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA056986: AB_2683300" "unprognostic (5.85e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (9.24e-2)" "unprognostic (9.35e-4)" "unprognostic (1.79e-4)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (9.51e-2)" "unprognostic (6.22e-3)" "unprognostic (4.00e-2)" "unprognostic (2.38e-4)" "unprognostic (8.86e-2)" "unprognostic (3.91e-2)" "unprognostic (3.40e-2)" "unprognostic (1.69e-2)" C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 98.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 64.7;Kupffer cells: 114.6;Macrophages: 50.5;monocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.3;eosinophil: 169.4;intermediate monocyte: 312.5;myeloid DC: 162.2;neutrophil: 230.1;non-classical monocyte: 392.8" "Group enriched" "Detected in all" 20 "dendritic cells: 162.2;granulocytes: 230.1;monocytes: 392.8" "Group enriched" "Detected in some" 4 "Leukemia: 11.1;lymphoma: 5.5;Myeloma: 5.9" "Kidney - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: AB_10603448, HPA055027: " "unprognostic (6.65e-3)" "prognostic favorable (2.43e-4)" "unprognostic (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-3)" "unprognostic (3.56e-1)" "unprognostic (8.27e-2)" "unprognostic (5.60e-2)" "unprognostic (6.02e-2)" "unprognostic (9.74e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.75e-7)" "unprognostic (2.31e-1)" "unprognostic (4.00e-2)" "unprognostic (1.03e-2)" "unprognostic (2.11e-2)" C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 361.1;Kupffer cells: 668.2;Langerhans cells: 256.1;Macrophages: 441.8;monocytes: 553.5;NK-cells: 193.9;Schwann cells: 450.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Leukemia: 20.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" C2CD4B "FAM148B, NLF2" ENSG00000205502 "C2 calcium dependent domain containing 4B" A6NLJ0 15 62163535-62165285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 172.3;Endothelial cells: 179.8;Enteroendocrine cells: 112.7;Glandular and luminal cells: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.5;ovarian cancer: 1.2" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells" HPA046880 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" "HPA046880: AB_10959458" "unprognostic (6.60e-2)" "prognostic favorable (4.22e-4)" "unprognostic (2.24e-2)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (4.06e-3)" "unprognostic (2.29e-1)" "unprognostic (5.02e-2)" "unprognostic (3.36e-2)" "unprognostic (2.33e-1)" "unprognostic (5.30e-2)" "unprognostic (1.83e-1)" "unprognostic (6.16e-3)" "unprognostic (7.89e-2)" "unprognostic (5.24e-1)" "unprognostic (8.64e-3)" "unprognostic (1.48e-1)" C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Group enriched" "Detected in some" 4 "Hepatocytes: 6.9;Thymic epithelial cells: 8.7" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 7.2;Myeloma: 7.8" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" C5orf49 LOC134121 ENSG00000215217 "Chromosome 5 open reading frame 49" A4QMS7 5 7830378-7851151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 29.1;choroid plexus: 27.4;fallopian tube: 75.7;testis: 37.1" "Group enriched" "Detected in many" 5 "Early spermatids: 734.1;Endometrial ciliated cells: 364.8;Late spermatids: 505.9;Respiratory ciliated cells: 458.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.7" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043759 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" "HPA043759: AB_2678655" "unprognostic (1.55e-1)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.13e-3)" "unprognostic (4.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (7.93e-2)" "unprognostic (7.54e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-2)" "unprognostic (2.20e-2)" C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;choroid plexus: 6.4;fallopian tube: 13.9" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 60.6;Respiratory ciliated cells: 71.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021286 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA021286: AB_1845760" "unprognostic (1.74e-2)" "unprognostic (4.82e-2)" "unprognostic (3.13e-2)" "unprognostic (1.28e-2)" "unprognostic (2.77e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.37e-1)" "unprognostic (4.98e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-5)" "unprognostic (5.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.42e-3)" "unprognostic (1.20e-1)" CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.9;cervix: 21.8;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1539.4" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7;thyroid cancer: 4.1" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116558868 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 23.1" "Group enriched" "Detected in some" 46 "Cytotrophoblasts: 27.2;Syncytiotrophoblasts: 87.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA048014: " "unprognostic (7.95e-2)" "unprognostic (3.44e-4)" "unprognostic (1.99e-1)" "unprognostic (1.44e-2)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.8;Gastric mucus-secreting cells: 22.7;Paneth cells: 12.4;Proximal enterocytes: 23.6;Proximal tubular cells: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 184.3;non-classical monocyte: 216.9" "Lineage enriched" "Detected in many" 7 "monocytes: 216.9" "Cancer enhanced" "Detected in all" "Myeloma: 77.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.0;dendritic cells: 36.4;Microglial cells: 48.3;NK-cells: 52.7;T-cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cancer enhanced" "Detected in many" "lymphoma: 69.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183668-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "parathyroid gland: 654.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 48.1;Enteroendocrine cells: 12.0;Granulosa cells: 20.7;Pancreatic endocrine cells: 17.2" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "thyroid cancer: 6.8" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA039686, HPA050335" Enhanced NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 17: Granulosa cells - Transcription regulation" "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2061.1;Alveolar cells type 1: 1354.7;Basal keratinocytes: 839.9;Endothelial cells: 1053.2;Smooth muscle cells: 716.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" CCDC102A MGC10992 ENSG00000135736 "Coiled-coil domain containing 102A" Q96A19 16 57512181-57536571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040598, HPA040958" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm "Nuclear bodies" "HPA040598: AB_10794035, HPA040958: AB_10794156" "unprognostic (3.46e-2)" "unprognostic (3.04e-2)" "unprognostic (1.88e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.42e-1)" "unprognostic (4.01e-3)" "unprognostic (7.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.38e-1)" "unprognostic (5.24e-3)" "unprognostic (8.40e-3)" "unprognostic (4.08e-1)" "unprognostic (2.75e-1)" "unprognostic (2.37e-1)" "unprognostic (8.42e-3)" CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 291.3;Fibroblasts: 994.9;Late spermatids: 492.2;Thymic epithelial cells: 831.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "cervical cancer: 356.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "head and neck cancer: 6.1;Leukemia: 21.8;lymphoma: 23.4;Myeloma: 15.7" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1411.1;Macrophages: 1080.9;monocytes: 1343.3;NK-cells: 4730.9;T-cells: 2177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Cancer enriched" "Detected in some" 5 "lymphoma: 53.2" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 10 "NK-cells: 2748.9;T-cells: 2015.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Group enriched" "Detected in many" 4 "head and neck cancer: 18.5;Leukemia: 60.2;lymphoma: 48.9;Myeloma: 36.5;thyroid cancer: 41.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 45.4;Glandular and luminal cells: 69.4;Melanocytes: 116.7;Smooth muscle cells: 67.9" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cancer enhanced" "Detected in many" "lung cancer: 42.6;skin cancer: 56.7" "Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Thyroid - Fibroblasts" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.8;Hofbauer cells: 50.5;Langerhans cells: 45.2;Macrophages: 49.2;monocytes: 93.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 6.6" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 4 "NK-cells: 202.8;T-cells: 464.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 88 "Leukemia: 10.9;lymphoma: 16.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 16.8" "Cell type enhanced" "Detected in some" "Kupffer cells: 12.7;Macrophages: 7.4;monocytes: 15.7;NK-cells: 40.4;T-cells: 18.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 472.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 472.1" "Cancer enriched" "Detected in some" 14 "Leukemia: 15.0" "Adipose subcutaneous - T-cells, Adipose visceral - Mesothelial cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 280000 "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (6.11e-3)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (6.95e-6)" "unprognostic (5.79e-2)" "unprognostic (1.43e-4)" "unprognostic (1.93e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (5.40e-4)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 22 "NK-cells: 788.2;T-cells: 243.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 24 "Leukemia: 23.3;lymphoma: 24.2;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 31.5;granulocytes: 32.3;Langerhans cells: 63.4;Syncytiotrophoblasts: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 10 "Hofbauer cells: 31.4;T-cells: 58.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Cancer enriched" "Detected in some" 14 "Myeloma: 98.7" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Skin - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 1: T-cells - Immune response" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 317.5;Kupffer cells: 276.3;Langerhans cells: 130.6;Macrophages: 206.1;monocytes: 167.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 68.6;Hofbauer cells: 91.5;Kupffer cells: 67.0;Langerhans cells: 50.7;Macrophages: 62.0;monocytes: 91.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cancer enriched" "Detected in many" 7 "Leukemia: 52.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Cell type enriched" "Detected in many" 6 "T-cells: 664.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 234.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 6 "NK-cells: 218.3;T-cells: 639.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Cancer enriched" "Detected in some" 7 "Leukemia: 123.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 4 "NK-cells: 96.8;T-cells: 326.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Cancer enriched" "Detected in some" 7 "Leukemia: 19.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 9 "T-cells: 77.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cancer enriched" "Detected in single" 14 "Leukemia: 2.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 361.7;granulocytes: 198.2;Hofbauer cells: 226.3;Kupffer cells: 257.1;Macrophages: 195.3;monocytes: 853.5;NK-cells: 408.9;Schwann cells: 201.6;T-cells: 432.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 207.9;Myeloma: 445.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.5" "Cell type enriched" "Detected in some" 4 "T-cells: 56.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 138.2" "Lineage enriched" "Detected in many" 33 "T-cells: 138.2" "Group enriched" "Detected in some" 9 "Leukemia: 17.2;lymphoma: 28.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Group enriched" "Detected in some" 8 "NK-cells: 40.8;T-cells: 99.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "Leukemia: 10.2;lymphoma: 14.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" CD69 CLEC2C ENSG00000110848 "CD69 molecule" Q07108 12 9752486-9760901 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 169.1;lymphoid tissue: 94.4" "Group enriched" "Detected in many" 5 "B-cells: 947.5;granulocytes: 1937.7;NK-cells: 517.3;T-cells: 1179.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 26.7;T-cells: 30.8" "Group enriched" "Detected in some" 6 "Leukemia: 44.2;lymphoma: 26.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002503, HPA050525" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "CAB002503: AB_563625, HPA050525: AB_2681157" "prognostic favorable (3.31e-5)" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-3)" "unprognostic (4.76e-3)" "unprognostic (9.53e-3)" "unprognostic (9.73e-3)" "unprognostic (1.64e-2)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.88e-2)" "unprognostic (3.32e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 153.9;Kupffer cells: 66.3;Langerhans cells: 193.7;Macrophages: 137.3;Microglial cells: 76.6;monocytes: 280.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Cell type enriched" "Detected in many" 4 "T-cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Group enriched" "Detected in some" 8 "Leukemia: 6.0;lymphoma: 10.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Cell type enriched" "Detected in many" 6 "T-cells: 154.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Group enriched" "Detected in some" 8 "Leukemia: 8.8;Myeloma: 33.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 6 "NK-cells: 121.7;T-cells: 195.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cancer enhanced" "Detected in many" "Leukemia: 31.4;skin cancer: 16.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 53: Non-specific - mRNA processing" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" CDC42SE2 "FLJ21967, SPEC2" ENSG00000158985 "CDC42 small effector 2" Q9NRR3 5 131245493-131398447 "Predicted intracellular proteins" "Cell shape, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Kidney - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038624 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 57: Non-specific - Translation" "Cluster 1: T-cells - Immune response" "HPA038624: AB_10670783" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "prognostic favorable (4.50e-5)" "unprognostic (2.37e-3)" "unprognostic (7.38e-2)" "unprognostic (4.31e-2)" "unprognostic (2.91e-3)" "unprognostic (2.11e-1)" "unprognostic (2.37e-1)" "unprognostic (8.65e-3)" "unprognostic (2.18e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-3)" "unprognostic (5.44e-2)" "unprognostic (3.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (7.50e-4)" CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Endometrial stromal cells: 115.4;Excitatory neurons: 120.0;Microglial cells: 141.4;Oligodendrocyte precursor cells: 151.6;Oligodendrocytes: 100.4;Theca cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 104.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_1, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.4;fallopian tube: 108.8" "Cell type enhanced" "Detected in many" "Astrocytes: 165.4;Endometrial ciliated cells: 139.7;Enteroendocrine cells: 92.1;Excitatory neurons: 69.1;Inhibitory neurons: 62.5;Respiratory ciliated cells: 291.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "lymphoma: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" HPA011218 Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" "HPA011218: AB_1078886" "unprognostic (4.38e-4)" "unprognostic (9.18e-2)" "unprognostic (8.16e-3)" "unprognostic (8.08e-3)" "unprognostic (5.23e-2)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.70e-3)" "unprognostic (3.51e-3)" CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 15.2;ovary: 6.1" "Group enriched" "Detected in some" 6 "Early spermatids: 27.2;granulocytes: 60.6;Late spermatids: 41.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Group enriched" "Detected in some" 28 "basophil: 1.8;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cancer enhanced" "Detected in many" "Kidney cancer: 9.6" "Adipose subcutaneous - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Kidney - Fibroblasts, Lung - Mast cells, Skin - Mast cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 100.1;Oligodendrocytes: 244.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 61: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 92.5;Extravillous trophoblasts: 79.2;Langerhans cells: 51.9;Melanocytes: 121.9;Syncytiotrophoblasts: 192.0" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 245.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388869-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Enhanced "Cell Junctions,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 59: Non-specific - Translation" "Cluster 55: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Centrosome "Cell Junctions" "CAB079753: AB_2665827, HPA035820: AB_10671939, HPA035821: , HPA046529: AB_2679688" "unprognostic (7.72e-2)" "unprognostic (2.04e-2)" "unprognostic (2.84e-2)" "unprognostic (4.48e-2)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" "unprognostic (6.70e-3)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (7.36e-2)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (4.94e-2)" "unprognostic (2.36e-1)" "unprognostic (3.33e-2)" "unprognostic (7.41e-2)" CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.8;Distal enterocytes: 144.9;Proximal enterocytes: 129.1;Squamous epithelial cells: 168.6;Suprabasal keratinocytes: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cancer enhanced" "Detected in many" "cervical cancer: 55.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327, HPA073143" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Nucleoplasm Cytosol "CAB000349: , HPA052838: , HPA063327: AB_2684987, HPA073143: " "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.8;Suprabasal keratinocytes: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" CEBPG "GPE1BP, IG/EBP-1" ENSG00000153879 "CCAAT enhancer binding protein gamma" P53567 19 33373685-33382686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012024 Enhanced Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 50: Enterocytes - Absorption" Nucleoplasm "HPA012024: AB_1846503" "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (3.29e-3)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.12e-2)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.16e-1)" "unprognostic (5.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.01e-2)" CELF3 "BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4" ENSG00000159409 "CUGBP Elav-like family member 3" Q5SZQ8 1 151700058-151716803 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.7;pituitary gland: 109.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 124.2;Cone photoreceptor cells: 70.7;Enteroendocrine cells: 41.0;Excitatory neurons: 20.8;Horizontal cells: 27.6;Inhibitory neurons: 19.9" "Group enriched" "Detected in many" 5 "glioma: 4.4;pancreatic cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Neuroblastoma: 67.7" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006292 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "HPA006292: AB_10602250" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (7.67e-2)" "unprognostic (1.96e-1)" "unprognostic (1.75e-1)" "unprognostic (6.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.02e-2)" "unprognostic (3.12e-1)" "unprognostic (3.48e-3)" "unprognostic (3.49e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-8)" "unprognostic (8.50e-2)" "unprognostic (9.01e-2)" "unprognostic (2.41e-1)" "unprognostic (3.05e-2)" CENATAC "CCDC84, DLNB14" ENSG00000186166 "Centrosomal AT-AC splicing factor" Q86UT8 11 118998138-119015793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 153.5;Rod photoreceptor cells: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039906, HPA071715" Uncertain Approved Nucleoplasm No No "Cluster 37: B-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA039906: AB_2676740, HPA071715: AB_2686436" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (1.54e-1)" "unprognostic (4.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-3)" "unprognostic (3.45e-2)" "unprognostic (4.64e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.93e-5)" "unprognostic (8.14e-2)" "unprognostic (8.24e-2)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 83.2;Excitatory neurons: 42.4;Horizontal cells: 96.8;Inhibitory neurons: 44.6" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.4;Rhabdoid: 26.2" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" CENPO "CENP-O, MGC11266" ENSG00000138092 "Centromere protein O" Q9BU64 2 24793136-24822376 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.2;Spermatocytes: 10.4;Spermatogonia: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA046189 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "Nuclear bodies" "HPA046189: AB_2679579" "unprognostic (1.67e-2)" "unprognostic (2.42e-1)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.79e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.56e-2)" "unprognostic (4.02e-1)" "unprognostic (4.81e-2)" "unprognostic (5.93e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.71e-13)" "unprognostic (4.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 591.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 109.7;Hepatocytes: 459.9;Muller glia cells: 116.0;Proximal tubular cells: 197.0" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 29: Hepatocytes - Metabolism" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells" "HPA038925, HPA038934" Supported "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 1209.9;Pancreatic endocrine cells: 647.5" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Gastric cancer: 82.4;lung cancer: 62.8;Neuroblastoma: 219.3;thyroid cancer: 189.6" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Testis - Spermatocytes, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Langerhans cells: 55.7;monocytes: 53.6;Peritubular cells: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.5" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.2;T-cells: 18.5" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 9800 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 218.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 41.2;Fibroblasts: 163.9;Leydig cells: 226.7;Peritubular cells: 56.4;Skeletal myocytes: 74.2;Theca cells: 79.2" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ovarian cancer: 3.8;Uterine cancer: 3.9" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" CLASP2 KIAA0627 ENSG00000163539 "Cytoplasmic linker associated protein 2" O75122 3 33496245-33718356 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 176.6;retina: 126.4" "Cell type enhanced" "Detected in all" "Astrocytes: 285.3;Excitatory neurons: 506.7;Inhibitory neurons: 514.1;Oligodendrocyte precursor cells: 708.5;Oligodendrocytes: 1242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067071 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA067071: AB_2685775" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (7.24e-3)" "unprognostic (5.46e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (1.27e-2)" "unprognostic (4.51e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-2)" "unprognostic (2.60e-3)" "unprognostic (3.25e-2)" "prognostic favorable (1.48e-6)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "unprognostic (1.07e-2)" "unprognostic (5.72e-2)" CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enhanced" "Detected in many" "dendritic cells: 49.9;Microglial cells: 45.6" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 11: Non-specific - Transcription" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" CLCNKB hClC-Kb ENSG00000184908 "Chloride voltage-gated channel Kb" P51801 1 16043736-16057308 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 209.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 25.6;Distal tubular cells: 28.0;Early spermatids: 12.6;Ionocytes: 15.0;Late spermatids: 82.3" "Cancer enriched" "Detected in some" 9 "renal cancer: 24.9" "Region enriched" "Detected in some" 6 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Testis - Late spermatids" HPA057717 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (9.05e-4)" "unprognostic (1.72e-1)" "unprognostic (2.41e-2)" "unprognostic (2.68e-3)" "unprognostic (1.44e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-4)" "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.27e-7)" "unprognostic (2.04e-2)" "unprognostic (4.62e-1)" "unprognostic (1.78e-2)" "unprognostic (5.14e-2)" CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 14 "Adipocytes: 2811.5;Endothelial cells: 858.8" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 7 "Bone cancer: 7.1;Leukemia: 3.4;lung cancer: 2.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 66: Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.9;intestine: 50.8;kidney: 69.3;salivary gland: 40.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 196.9;Distal enterocytes: 86.8;Salivary duct cells: 37.7" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 16.7;prostate cancer: 8.9" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 384.2;Endothelial cells: 325.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Leukemia: 8.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Group enriched" "Detected in many" 8 "Hofbauer cells: 188.6;Kupffer cells: 344.7;Langerhans cells: 338.1;Macrophages: 242.9;monocytes: 527.0;Schwann cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 12 "Myeloma: 69.4" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Alveolar cells type 1: 79.0;Alveolar cells type 2: 44.9;Endothelial cells: 53.3;Langerhans cells: 140.8;Macrophages: 37.8;Schwann cells: 73.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Cancer enhanced" "Detected in many" "Myeloma: 35.7" "Breast - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99897134 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.7" "Cell type enhanced" "Detected in all" "Astrocytes: 82.2;Distal tubular cells: 121.3;Hepatocytes: 113.1;Proximal tubular cells: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 7300 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: Non-specific - Nuclear processes" "Cluster 60: Proximal tubular cells - Absorption" "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049095 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 8400000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 68: Kidney - Mixed function" "Cluster 2: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Actin filaments" "HPA049095: AB_2680627" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (1.74e-1)" "unprognostic (4.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.70e-7)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (2.50e-1)" "unprognostic (1.54e-1)" CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 553.1" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 66: Endothelial cells - Angiogenesis" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.9;Leydig cells: 34.7;Peritubular cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 740.2;Excitatory neurons: 832.7;Inhibitory neurons: 682.3;Oligodendrocyte precursor cells: 978.1" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 239.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 152.7;Endometrial stromal cells: 70.3;Excitatory neurons: 52.0;Fibroblasts: 131.6;Leydig cells: 68.5;Smooth muscle cells: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 267.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 105.6;Oligodendrocyte precursor cells: 59.7;Oligodendrocytes: 115.2;Peritubular cells: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 55.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027235 Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA027235: AB_1847101" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1863.1;Fibroblasts: 1830.1;Leydig cells: 557.7;Pancreatic endocrine cells: 1576.7;Smooth muscle cells: 657.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1245.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 15.7;Basal respiratory cells: 16.4;Cardiomyocytes: 10.2;Microglial cells: 8.2;Peritubular cells: 10.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 18.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 72: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 129.4;Fibroblasts: 126.5;Leydig cells: 61.6;Pancreatic endocrine cells: 61.8;Schwann cells: 50.9;Smooth muscle cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 233.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 494.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 8.5;skin cancer: 8.1" "Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 441.3;Fibroblasts: 1248.3;Leydig cells: 579.0;Peritubular cells: 443.1;Smooth muscle cells: 597.2;Thymic epithelial cells: 303.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 487.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 213.4;Endometrial stromal cells: 331.7;Fibroblasts: 695.7;Leydig cells: 305.8;Smooth muscle cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 354.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_2" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.9;Basal respiratory cells: 59.2;Basal squamous epithelial cells: 44.3;Endometrial stromal cells: 39.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Endothelial cells" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 143.0;Hofbauer cells: 132.0;Microglial cells: 239.0;Syncytiotrophoblasts: 97.6" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 905.2;Syncytiotrophoblasts: 638.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Bipolar cells: 39.4;Excitatory neurons: 95.3;Inhibitory neurons: 48.9;Oligodendrocytes: 138.2" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Endothelial cells, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" CPED1 "C7orf58, FLJ21986" ENSG00000106034 "Cadherin like and PC-esterase domain containing 1" A4D0V7 7 120988697-121297442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 78.5" "Cell type enhanced" "Detected in many" "Microglial cells: 223.5;Peritubular cells: 84.4;Skeletal myocytes: 55.4;Theca cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 10.8;intermediate monocyte: 11.3;myeloid DC: 25.2;non-classical monocyte: 7.6;plasmacytoid DC: 15.0" "Group enriched" "Detected in many" 9 "dendritic cells: 25.2;monocytes: 11.3" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012058 Uncertain Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA012058: AB_1845761" "unprognostic (7.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (4.48e-4)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.52e-3)" "prognostic favorable (3.00e-4)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (8.69e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.28e-3)" "unprognostic (5.05e-2)" "unprognostic (3.78e-1)" "unprognostic (6.54e-4)" CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 113.9;Microglial cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 166.2;Late spermatids: 505.2;Proximal enterocytes: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 65: Breast cancer - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 454.9;Cone photoreceptor cells: 118.9;Inhibitory neurons: 126.9;Oligodendrocyte precursor cells: 268.1;Oligodendrocytes: 99.7;Rod photoreceptor cells: 152.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Group enriched" "Detected in some" 5 "cervical cancer: 6.3;Sarcoma: 4.8" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 61: Liver - Metabolism" "Cluster 63: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 225.4;Plasma cells: 187.5;Syncytiotrophoblasts: 166.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 27.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 65.1;Inhibitory neurons: 26.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 12 "amygdala: 8.7;basal ganglia: 17.2;cerebral cortex: 26.3;hippocampal formation: 27.8;white matter: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038224 Enhanced "Secreted in brain" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Enzymes" "Cluster 38: Neurons - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Muller glia cells: 3.9;Proximal tubular cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 60: Proximal tubular cells - Absorption" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" CRYGN ENSG00000127377 "Crystallin gamma N" Q8WXF5 7 151428832-151440813 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "thyroid gland: 15.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Basal prostatic cells: 1.7;Breast myoepithelial cells: 1.5;Endometrial stromal cells: 1.4" "Cancer enriched" "Detected in some" 25 "thyroid cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 1.1;naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Not detected" "Not detected" "Colon - Enteric glia cells, Kidney - Fibroblasts" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;white matter: 11.4" "Not detected" "Not detected" HPA050788 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA050788: AB_2681239" "unprognostic (1.69e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-3)" "unprognostic (5.50e-2)" "unprognostic (2.94e-5)" "unprognostic (2.49e-3)" "unprognostic (1.55e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (3.67e-2)" "unprognostic (1.39e-1)" "unprognostic (8.48e-2)" "unprognostic (8.93e-10)" "unprognostic (2.55e-4)" "unprognostic (2.71e-1)" "unprognostic (2.36e-2)" "unprognostic (3.36e-1)" CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 963.3;Extravillous trophoblasts: 424.0;Smooth muscle cells: 499.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enhanced" "Detected in all" "Langerhans cells: 22509.9;Schwann cells: 11118.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" CTCF "CFAP108, FAP108" ENSG00000102974 "CCCTC-binding factor" P49711 16 67562467-67639177 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 63: T-cells - Adaptive immune response" "Cluster 36: Non-specific - Unknown function" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm "CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139" "unprognostic (2.70e-1)" "unprognostic (4.21e-2)" "unprognostic (3.41e-2)" "unprognostic (4.70e-2)" "unprognostic (4.41e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.71e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (1.99e-2)" "prognostic favorable (4.06e-4)" "unprognostic (3.47e-1)" "unprognostic (5.99e-2)" "unprognostic (4.58e-2)" "unprognostic (1.11e-2)" CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Group enriched" "Detected in some" 8 "Schwann cells: 28.4;T-cells: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.9;skin cancer: 5.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Kidney - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 1: T-cells - Immune response" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 310.9;Hofbauer cells: 299.4;Proximal enterocytes: 289.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 4: Platelets - Platelet activation" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2520.2;Kupffer cells: 1044.3;Macrophages: 1561.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 69: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 8 "NK-cells: 922.6;T-cells: 340.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Cancer enriched" "Detected in some" 11 "Leukemia: 42.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 297.3;Distal tubular cells: 118.2;Endothelial cells: 139.5;Fibroblasts: 456.2;Smooth muscle cells: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 47.1;testis cancer: 63.6" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1675.4;dendritic cells: 2180.0;monocytes: 1143.3;NK-cells: 1206.4;Schwann cells: 1000.5;T-cells: 1642.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 184.9;lymphoma: 220.2;Myeloma: 144.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Skin - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 88.1;T-cells: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 445.8" "Lineage enriched" "Detected in many" 5 "T-cells: 445.8" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0" "Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Fibroblasts: 75.3;Leydig cells: 89.1;Melanocytes: 102.8;Sertoli cells: 41.5;Smooth muscle cells: 69.9" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Neuroblastoma: 93.0;skin cancer: 107.6" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 65: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSG00000231852 "Cytochrome P450 family 21 subfamily A member 2" P08686 6 32038327-32041644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "adrenal gland: 2041.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Hepatocytes: 11.0;Proximal tubular cells: 1.9;Salivary duct cells: 3.9;Thymic epithelial cells: 2.8" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048979, HPA053371" Enhanced NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 29: Hepatocytes - Metabolism" "HPA048979: AB_2680584, HPA053371: AB_2682131" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-4)" "unprognostic (2.58e-1)" "unprognostic (2.97e-1)" "unprognostic (2.93e-2)" "unprognostic (2.76e-2)" "unprognostic (8.75e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (6.67e-7)" "unprognostic (7.39e-2)" "unprognostic (5.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.82e-1)" CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 1625.4" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.8;liver cancer: 1.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 110.7;Cytotrophoblasts: 116.1;Oligodendrocytes: 64.6;Proximal enterocytes: 118.1;Syncytiotrophoblasts: 255.4" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 29.7;Inhibitory neurons: 33.6;Melanocytes: 27.9;Schwann cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 59 "Hepatocytes: 2605.9;Proximal enterocytes: 1368.9" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.2;Gastric mucus-secreting cells: 58.4;Intestinal goblet cells: 32.0;Paneth cells: 45.9;Proximal enterocytes: 115.4;Suprabasal keratinocytes: 41.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cancer enhanced" "Detected in many" "Gastric cancer: 5.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Urothelial cells, Thyroid - Fibroblasts" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" CYTH3 "ARNO3, cytohesin-3, GRP1, PSCD3" ENSG00000008256 "Cytohesin 3" O43739 7 6161776-6272644 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 65.5;Inhibitory neurons: 94.3;Melanocytes: 55.7;Microglial cells: 55.6" "Cancer enriched" "Detected in all" 5 "melanoma: 47.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013979 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 37: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA013979: AB_1855799" "unprognostic (6.58e-2)" "unprognostic (1.37e-2)" "unprognostic (1.65e-2)" "unprognostic (5.75e-3)" "unprognostic (1.27e-3)" "unprognostic (1.27e-2)" "unprognostic (2.32e-2)" "unprognostic (2.63e-1)" "unprognostic (8.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (1.73e-2)" "unprognostic (2.20e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (2.63e-5)" CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 190.8;Endothelial cells: 162.0;Microglial cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cancer enhanced" "Detected in many" "Bone cancer: 14.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" DACT1 "DAPPER, DAPPER1, FRODO, HDPR1, THYEX3" ENSG00000165617 "Dishevelled binding antagonist of beta catenin 1" Q9NYF0 14 58633967-58648321 "Disease related genes, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.7;Late spermatids: 17.1;Peritubular cells: 28.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 17.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003016, HPA074619" Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "HPA003016: AB_1078623, HPA074619: " "unprognostic (2.47e-2)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (3.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (4.79e-2)" "unprognostic (1.93e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 15.1" "Group enriched" "Detected in all" 7 "Early spermatids: 630.5;Spermatocytes: 474.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 341.3;Langerhans cells: 321.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 91.2;Late spermatids: 146.4;NK-cells: 73.5;T-cells: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 75.5;Myeloma: 54.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 2: T-cells - T-cell receptor" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1746.1;pancreas: 747.8;salivary gland: 1975.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1865.1;Distal tubular cells: 12886.7;Ductal cells: 1858.4;Mucus glandular cells: 5908.3;Salivary duct cells: 3380.1" "Cancer enhanced" "Detected in many" "renal cancer: 522.9" "Group enriched" "Detected in many" 4 "amygdala: 1.2;cerebellum: 1.5;hypothalamus: 1.0;midbrain: 2.4;thalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 56.1;ovarian cancer: 42.9" "Kidney - Intercalated cells" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 16: Non-specific - RNA binding" "unprognostic (2.31e-2)" "unprognostic (8.35e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-3)" "unprognostic (4.41e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (5.94e-4)" "unprognostic (3.24e-1)" "prognostic favorable (1.90e-5)" "unprognostic (9.62e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" DENND2C "dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1" ENSG00000175984 "DENN domain containing 2C" Q68D51 1 114582848-114670422 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.7;skeletal muscle: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.0;Endometrial ciliated cells: 90.9;Glandular and luminal cells: 147.3;Skeletal myocytes: 131.6;Squamous epithelial cells: 118.2;Suprabasal keratinocytes: 186.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bone cancer: 10.9;Myeloma: 9.9" "Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029935, HPA054955" Uncertain Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 59: Non-specific - Translation" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA029935: AB_10601208, HPA054955: AB_2682648" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "unprognostic (9.97e-2)" "unprognostic (4.89e-4)" "unprognostic (1.52e-1)" "unprognostic (2.46e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (2.20e-2)" "unprognostic (7.43e-2)" "unprognostic (2.77e-2)" "unprognostic (2.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.57e-2)" DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 21.2;Erythroid cells: 31.3;Extravillous trophoblasts: 22.6;Spermatocytes: 34.6;Syncytiotrophoblasts: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Intercalated cells, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 206.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617" "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 173.4;Endothelial cells: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 632.7;Excitatory neurons: 1257.4;Inhibitory neurons: 701.1;Oligodendrocyte precursor cells: 1112.4;Oligodendrocytes: 576.0;Rod photoreceptor cells: 401.8;Skeletal myocytes: 722.5" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 47: Retina - Visual perception" "Cluster 38: Neurons - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 22.8;Hepatocytes: 30.7;Proximal tubular cells: 26.6;Squamous epithelial cells: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.2" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 14: Endometrium - Transcription regulation" Vesicles "HPA044764: AB_10959788, HPA062253: AB_2684726" "unprognostic (1.47e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.67e-3)" "unprognostic (4.36e-2)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.64e-2)" "unprognostic (3.65e-3)" "unprognostic (2.92e-1)" "prognostic favorable (1.14e-6)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (8.53e-3)" DNAH17 "DNAHL1, DNEL2, FLJ40457" ENSG00000187775 "Dynein axonemal heavy chain 17" Q9UFH2 17 78423697-78577396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 2.1;retina: 2.5;testis: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 55.6;Cone photoreceptor cells: 22.4;Early spermatids: 30.2;Late spermatids: 41.9;Oligodendrocytes: 49.6;Spermatocytes: 13.6" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.9;lung cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.3" "Kidney - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA024354, HPA076261" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 35: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" Cytosol "HPA024354: AB_1847911, HPA076261: AB_2732305" "unprognostic (4.98e-4)" "unprognostic (2.26e-1)" "unprognostic (2.30e-3)" "unprognostic (8.70e-3)" "unprognostic (6.66e-2)" "unprognostic (9.23e-2)" "unprognostic (3.72e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.20e-3)" "unprognostic (8.35e-3)" "unprognostic (1.58e-10)" "unprognostic (5.25e-2)" "unprognostic (1.54e-1)" "unprognostic (5.12e-1)" "unprognostic (6.04e-3)" DNAJC12 JDP1 ENSG00000108176 "DnaJ heat shock protein family (Hsp40) member C12" Q9UKB3 10 67796669-67838188 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 70.3;liver: 67.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 81.0;Enteroendocrine cells: 137.3;Hepatocytes: 102.7;Pancreatic endocrine cells: 147.7;Proximal tubular cells: 150.5" "Cancer enhanced" "Detected in many" "breast cancer: 22.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 7.7" "Lineage enriched" "Detected in single" 24 "dendritic cells: 7.7" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036289 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 30: Breast - Lactation" "HPA036289: AB_10670794" "unprognostic (1.52e-2)" "unprognostic (3.65e-3)" "unprognostic (4.12e-2)" "unprognostic (2.28e-2)" "unprognostic (5.28e-2)" "unprognostic (6.59e-3)" "unprognostic (6.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (5.05e-2)" "unprognostic (3.97e-2)" "unprognostic (7.31e-3)" "prognostic unfavorable (1.97e-10)" "unprognostic (7.35e-3)" "unprognostic (1.37e-1)" "unprognostic (5.81e-3)" "unprognostic (7.99e-2)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 24.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.3;Distal enterocytes: 31.8;Enteroendocrine cells: 33.0;Hepatocytes: 38.5;Intestinal goblet cells: 31.8;Paneth cells: 34.1;Proximal enterocytes: 56.8;Thymic epithelial cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in all" 12 "Proximal enterocytes: 654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881466 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 211.8;Paneth cells: 141.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" NA NA 560000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 19: Macrophages - Innate immune response" "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" DNPH1 "C6orf108, dJ330M21.3, rcl" ENSG00000112667 "2'-deoxynucleoside 5'-phosphate N-hydrolase 1" O43598 6 43225629-43229481 "Predicted intracellular proteins" "Nucleotide metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 844.2;Proximal tubular cells: 1015.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029675, HPA029676" Enhanced Approved Nucleoplasm,Cytosol No No 540000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 57: Non-specific - Translation" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm Cytosol "HPA029675: AB_10599998, HPA029676: AB_10599424" "unprognostic (1.12e-2)" "unprognostic (1.38e-1)" "unprognostic (4.03e-3)" "unprognostic (8.24e-3)" "unprognostic (1.69e-1)" "unprognostic (3.53e-2)" "unprognostic (2.61e-1)" "unprognostic (7.72e-2)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (2.25e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-1)" "unprognostic (5.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (5.10e-2)" DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 766.4;Excitatory neurons: 415.9;Microglial cells: 1526.9;Oligodendrocyte precursor cells: 415.9;Oligodendrocytes: 769.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 64.2;Endothelial cells: 47.2;Gastric mucus-secreting cells: 32.8;Microglial cells: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 6 "B-cells: 31.5;granulocytes: 20.6;Hofbauer cells: 58.7;Kupffer cells: 55.3;Macrophages: 38.7;monocytes: 44.6;Plasma cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cancer enhanced" "Detected in all" "Leukemia: 72.7;lymphoma: 107.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 187.1;Excitatory neurons: 233.1;Inhibitory neurons: 253.0;Oligodendrocyte precursor cells: 170.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.4;testis cancer: 7.6" "Kidney - Proximal tubular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.3;Prostatic glandular cells: 199.1;Proximal enterocytes: 281.4;Serous glandular cells: 123.3;Syncytiotrophoblasts: 169.5" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Fibroblast_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1616.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" DTHD1 FLJ16686 ENSG00000197057 "Death domain containing 1" Q6ZMT9 4 36281616-36347511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.8;fallopian tube: 13.7;lung: 3.5;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "Early spermatids: 110.7;Endometrial ciliated cells: 135.2;NK-cells: 67.2;Respiratory ciliated cells: 174.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 56: Ciliated cells - Cilium assembly" "unprognostic (9.79e-6)" "unprognostic (4.04e-2)" "unprognostic (1.15e-2)" "unprognostic (5.54e-3)" "unprognostic (2.85e-1)" "unprognostic (5.45e-5)" "unprognostic (5.12e-3)" "unprognostic (9.11e-2)" "unprognostic (1.82e-2)" "unprognostic (7.59e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.05e-5)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.65e-2)" "unprognostic (7.12e-3)" DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 421.3;tongue: 204.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.9;Cardiomyocytes: 60.5;Cone photoreceptor cells: 98.2;Rod photoreceptor cells: 54.7;Skeletal myocytes: 120.7" "Cancer enhanced" "Detected in some" "glioma: 6.7;pancreatic cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.7;Neuroblastoma: 28.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350684 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.2;stomach 1: 32.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 500.2;Exocrine glandular cells: 187.3;Glandular and luminal cells: 165.8;Schwann cells: 397.7" "Cancer enhanced" "Detected in all" "melanoma: 42.9" "Region enhanced" "Detected in many" "hippocampal formation: 20.9" "Immune cell enriched" "Detected in single" 9 "T-reg: 6.7" "Lineage enriched" "Detected in single" 20 "T-cells: 6.7" "Cancer enhanced" "Detected in all" "skin cancer: 143.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077183 Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA077183: " "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347235-89352501 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 226.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 196.9;granulocytes: 243.1;Kupffer cells: 231.4;Macrophages: 216.8;monocytes: 227.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 97.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1636.7" "Group enriched" "Detected in all" 13 "granulocytes: 1636.7;monocytes: 842.3" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favorable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 27.6;Endothelial cells: 42.2;Excitatory neurons: 34.3;Oligodendrocytes: 59.1;Skeletal myocytes: 38.6;Syncytiotrophoblasts: 66.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Ductal cells: 283.0;Endometrial ciliated cells: 211.2;Endothelial cells: 212.0;Enteroendocrine cells: 235.7;Exocrine glandular cells: 329.5;Glandular and luminal cells: 315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cancer enhanced" "Detected in many" "Kidney cancer: 82.5;testis cancer: 117.2" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 14: Endometrium - Transcription regulation" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 106.0;Leydig cells: 95.6;Muller glia cells: 83.7;Peritubular cells: 102.7;Smooth muscle cells: 99.7;Theca cells: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 97.5;Basal squamous epithelial cells: 89.8;Extravillous trophoblasts: 87.5;Granulosa cells: 136.9;Theca cells: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;esophagus: 43.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 35.7;Kupffer cells: 36.3;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.8;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.8" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Approved "Plasma membrane" NA NA 15000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (3.44e-1)" "unprognostic (8.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (5.49e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.72e-2)" "unprognostic (9.92e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (4.88e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-3)" "unprognostic (4.92e-3)" EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 156.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 12: Non-specific - Chromatin organization" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 171.3;Endothelial cells: 171.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.1;Fibroblasts: 140.8;Leydig cells: 109.7;Peritubular cells: 137.6;Skeletal myocytes: 116.8;Smooth muscle cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 67.3;Sarcoma: 195.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.2;Fibroblasts: 118.1;Leydig cells: 84.6;Peritubular cells: 165.2;Smooth muscle cells: 59.5;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 105.1" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 811.4;Basal keratinocytes: 635.2;Endothelial cells: 499.2;Squamous epithelial cells: 933.1;Suprabasal keratinocytes: 1153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cancer enhanced" "Detected in all" "Rhabdoid: 567.9" "Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.1;kidney: 36.4" "Group enriched" "Detected in some" 4 "Collecting duct cells: 41.4;Excitatory neurons: 12.9;Proximal tubular cells: 30.8" "Cancer enriched" "Detected in some" 5 "renal cancer: 3.7" "Region enriched" "Detected in some" 10 "cerebral cortex: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "amygdala: 2.7;cerebral cortex: 10.5;hippocampal formation: 7.8" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: AB_2667542, HPA006421: AB_1078739" "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (8.71e-2)" "unprognostic (2.22e-6)" "unprognostic (4.82e-2)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (2.99e-1)" "unprognostic (3.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-3)" "unprognostic (5.02e-2)" ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 64: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.4;lymphoid tissue: 15.0" "Group enriched" "Detected in some" 4 "NK-cells: 79.7;T-cells: 32.0" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Region enriched" "Detected in single" 13 "cerebellum: 8.4" "Group enriched" "Detected in many" 7 "gdT-cell: 16.5;MAIT T-cell: 26.2;memory CD8 T-cell: 19.5;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Group enriched" "Detected in some" 6 "lymphoma: 4.7;Rhabdoid: 8.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Thyroid - T-cells" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 27 "cerebellum: 30.2;olfactory bulb: 12.7" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: AB_10601370" "unprognostic (1.53e-4)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.60e-4)" "unprognostic (4.13e-2)" "unprognostic (9.63e-4)" "unprognostic (4.29e-4)" "unprognostic (3.14e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (6.32e-3)" "unprognostic (1.49e-2)" EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Late spermatids: 349.9;Microglial cells: 422.3;Muller glia cells: 397.8;Rod photoreceptor cells: 1231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 192.6;dendritic cells: 111.8;Early spermatids: 41.8;Excitatory neurons: 47.3;Inhibitory neurons: 43.3;Late spermatids: 41.7;Oligodendrocyte precursor cells: 74.6" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Cancer enhanced" "Detected in many" "lymphoma: 11.2" "Breast - Breast myoepithelial cells, Kidney - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" ERICH5 "C8orf47, FLJ39553" ENSG00000177459 "Glutamate rich 5" Q6P6B1 8 98064522-98093610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 34.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 107.8;Ductal cells: 53.2;Endometrial ciliated cells: 29.9;Proximal tubular cells: 25.5;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "liver cancer: 23.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 2.2" "Lineage enriched" "Detected in single" 11 "dendritic cells: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA025070, HPA025293, HPA027233" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: Non-specific - Cilium assembly" "Cluster 74: Pancreatic cells - Mixed function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA025070: AB_1845778, HPA025293: AB_1845779, HPA027233: AB_1845780" "unprognostic (2.88e-3)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (6.86e-2)" "unprognostic (2.39e-1)" "unprognostic (8.66e-2)" "unprognostic (1.57e-1)" "unprognostic (4.66e-1)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (5.73e-1)" "prognostic favorable (3.76e-4)" "unprognostic (4.36e-2)" "unprognostic (9.22e-2)" "unprognostic (3.17e-2)" "prognostic favorable (9.38e-4)" ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.3;Hepatocytes: 383.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 4: Platelets - Platelet activation" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1230.0;Proximal enterocytes: 725.2;Proximal tubular cells: 981.1" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 244.0;Endothelial cells: 180.2;NK-cells: 650.0;T-cells: 359.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 712.9;Glandular and luminal cells: 526.8;monocytes: 507.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.0;monocytes: 32.4" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: AB_2666824" "unprognostic (2.06e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (5.33e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (7.36e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" "unprognostic (8.10e-2)" "unprognostic (7.10e-2)" EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Cell type enhanced" "Detected in some" "Adipocytes: 18.8;Endothelial cells: 27.7;Fibroblasts: 7.6;Kupffer cells: 8.9;Spermatogonia: 9.9;Theca cells: 23.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402141-177409564 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "liver: 604.6" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 379.9" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 1.2;eosinophil: 3.6" "Group enriched" "Detected in many" 5 "granulocytes: 3.6;monocytes: 1.2" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA003825 Approved "Secreted to blood" NA NA 1040000 7000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 29: Hepatocytes - Metabolism" "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 680.9;Basal respiratory cells: 349.4;Club cells: 393.3;Exocrine glandular cells: 480.8;Ionocytes: 314.5;Peritubular cells: 515.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "head and neck cancer: 689.5" "Kidney - Podocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Group enriched" "Detected in many" 4 "Cholangiocytes: 96.2;Cytotrophoblasts: 84.2;Hepatocytes: 223.3;Syncytiotrophoblasts: 61.1" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Cancer enhanced" "Detected in many" "liver cancer: 17.0" "Breast - Adipocytes (Breast), Kidney - Podocytes, Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Endothelial cells: 206.2;Fibroblasts: 40.9" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 48: Non-specific - RNA binding" "Cluster 66: Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 310.6;Proximal tubular cells: 255.0" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 13 "Adipocytes: 93.7;Endothelial cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 27: TE 441.T - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" FAM117A ENSG00000121104 "Family with sequence similarity 117 member A" Q9C073 17 49710332-49789180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 83.0;NK-cells: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 50.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 60.7" "Kidney - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022531 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Nucleoplasm "HPA022531: AB_2101087" "prognostic favorable (5.30e-5)" "unprognostic (8.06e-3)" "unprognostic (2.82e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-1)" "unprognostic (3.90e-3)" "unprognostic (1.69e-1)" "prognostic favorable (8.25e-7)" "unprognostic (4.05e-1)" "unprognostic (3.58e-1)" "prognostic favorable (1.81e-4)" "unprognostic (1.99e-2)" "unprognostic (3.73e-2)" "unprognostic (9.12e-2)" "unprognostic (1.45e-1)" "unprognostic (4.07e-2)" "unprognostic (4.66e-2)" FAM135A "FLJ20176, KIAA1411" ENSG00000082269 "Family with sequence similarity 135 member A" Q9P2D6 6 70412941-70561174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 167.7;Inhibitory neurons: 168.9;Microglial cells: 128.6;Oligodendrocyte precursor cells: 209.9;Oligodendrocytes: 114.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031743, HPA031744" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA031743: AB_10600767, HPA031744: AB_10601101" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "prognostic favorable (8.00e-4)" "unprognostic (1.59e-1)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (6.69e-4)" "unprognostic (4.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "prognostic favorable (3.46e-4)" "unprognostic (3.99e-1)" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "unprognostic (2.65e-2)" FAM217A "C6orf146, MGC43581" ENSG00000145975 "Family with sequence similarity 217 member A" Q8IXS0 6 4049434-4087344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 14.9" "Group enriched" "Detected in some" 19 "Early spermatids: 253.7;Late spermatids: 424.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" HPA035455 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 6: Late spermatids - Spermatogenesis" "HPA035455: AB_10669905" "unprognostic (5.93e-2)" "unprognostic (3.70e-2)" "unprognostic (1.24e-1)" "unprognostic (8.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.53e-2)" "unprognostic (2.99e-2)" "unprognostic (1.08e-2)" "unprognostic (2.09e-2)" "unprognostic (1.13e-1)" "unprognostic (1.85e-1)" "unprognostic (4.54e-1)" "unprognostic (6.55e-2)" "unprognostic (2.86e-1)" "unprognostic (1.85e-1)" "unprognostic (1.53e-2)" "unprognostic (5.51e-2)" FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 31.8;Cone photoreceptor cells: 39.6;Horizontal cells: 39.7;Oligodendrocytes: 74.1;Rod photoreceptor cells: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 45.2" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 271.8;Endothelial cells: 98.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 111.3;vagina: 55.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 32.0;Basal respiratory cells: 69.3;Club cells: 51.3;Ionocytes: 52.7;Squamous epithelial cells: 20.2;Suprabasal keratinocytes: 23.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 52.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 90.4" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Nucleoplasm Cytosol "HPA052615: AB_2797244" "unprognostic (4.48e-2)" "unprognostic (2.03e-3)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.98e-9)" "unprognostic (2.62e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (2.04e-1)" "unprognostic (2.22e-16)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "unprognostic (6.07e-2)" FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Basal squamous epithelial cells: 40.5;Squamous epithelial cells: 35.5;Suprabasal keratinocytes: 49.9;Syncytiotrophoblasts: 26.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.3" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 7 "NK-cells: 72.9;T-cells: 26.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.7;Fibroblasts: 429.8;Inhibitory neurons: 120.7;Leydig cells: 240.1;Oligodendrocytes: 206.4;Peritubular cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 81.0;thyroid cancer: 77.9" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Group enriched" "Detected in many" 4 "Hofbauer cells: 203.5;Kupffer cells: 184.5;Langerhans cells: 426.8;Macrophages: 271.2;monocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 31.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "dendritic cells: 19.5;Langerhans cells: 17.7;Oligodendrocytes: 44.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 33.4;lymphoma: 45.9" "Adipose subcutaneous - Macrophages, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 4: Platelets - Platelet activation" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 46.2;Late spermatids: 10.8;NK-cells: 29.1;T-cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cancer enriched" "Detected in single" 67 "lymphoma: 14.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Testis - Late spermatids" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 66.4;dendritic cells: 58.3;Kupffer cells: 85.5;Langerhans cells: 53.1;Macrophages: 56.6;Microglial cells: 42.0;monocytes: 117.4;Schwann cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Group enriched" "Detected in some" 6 "Leukemia: 2.8;lymphoma: 9.5;Myeloma: 3.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 53.9;Fibroblasts: 52.9;Leydig cells: 25.1;Peritubular cells: 33.3" "Cancer enriched" "Detected in some" 6 "breast cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 3.0;Neuroblastoma: 4.9;Sarcoma: 1.5" "Kidney - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 65: Fibroblasts - ECM organization" "CAB010315: AB_2262731" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (4.06e-3)" "unprognostic (2.72e-2)" "unprognostic (6.73e-2)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.14e-2)" "unprognostic (5.23e-4)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 179.2;Leydig cells: 196.8;Oligodendrocyte precursor cells: 159.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 202.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 453.6;Skeletal myocytes: 330.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.2" "Breast - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 200.4;Early spermatids: 339.9;Late spermatids: 227.0;Sertoli cells: 232.2;Smooth muscle cells: 334.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 37.6" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 1156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 133.2;Endometrial stromal cells: 56.9;Fibroblasts: 58.1;Late spermatids: 49.8;Leydig cells: 66.1;Peritubular cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FLRT1 "MGC21624, SPG68" ENSG00000126500 "Fibronectin leucine rich transmembrane protein 1" 11 64103188-64119173 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 8.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 8.7;Horizontal cells: 7.7;Inhibitory neurons: 15.7;Muller glia cells: 5.8;Oligodendrocyte precursor cells: 30.8;Oligodendrocytes: 12.4;Schwann cells: 9.5" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.6" "Colon - Enteric glia cells, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054589 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA054589: AB_2682533" "unprognostic (5.13e-3)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (8.65e-2)" "unprognostic (2.89e-1)" "unprognostic (9.55e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (2.98e-1)" "unprognostic (4.64e-3)" "unprognostic (6.02e-2)" "unprognostic (1.79e-1)" "unprognostic (2.62e-2)" "unprognostic (5.62e-2)" "unprognostic (1.29e-3)" "unprognostic (4.37e-2)" FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Adipocytes: 23.7;Endothelial cells: 36.2;Extravillous trophoblasts: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cancer enhanced" "Detected in many" "Sarcoma: 6.0" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 27: TE 441.T - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 277.6;lymphoid tissue: 104.9" "Cell type enhanced" "Detected in many" "B-cells: 102.2;dendritic cells: 123.8;Kupffer cells: 94.2;Langerhans cells: 178.4;Macrophages: 113.9;monocytes: 208.5;NK-cells: 191.6;Schwann cells: 91.4;T-cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Leukemia: 72.1;lymphoma: 88.8;Myeloma: 125.1" "Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA008129: AB_1848963, HPA028288: AB_10612110" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (8.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (5.44e-2)" "unprognostic (6.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "prognostic unfavorable (4.23e-8)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.16e-1)" FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 48.6;liver: 61.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.8;Oligodendrocytes: 17.5;Proximal enterocytes: 16.1;Proximal tubular cells: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" FOXD1 "FKHL8, FREAC4" ENSG00000251493 "Forkhead box D1" Q16676 5 73444827-73448777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.6;Fibroblasts: 5.4;Microglial cells: 9.1;Muller glia cells: 17.6;Proximal enterocytes: 5.4;Smooth muscle cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 9.6" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (7.06e-4)" "unprognostic (1.02e-3)" "unprognostic (3.00e-5)" "unprognostic (1.48e-4)" "unprognostic (1.09e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.11e-2)" "unprognostic (2.24e-2)" "unprognostic (2.26e-1)" "unprognostic (7.92e-2)" "unprognostic (2.06e-2)" "unprognostic (6.18e-2)" "unprognostic (2.61e-10)" "unprognostic (3.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (9.65e-4)" FOXD2 "FKHL17, FREAC9" ENSG00000186564 "Forkhead box D2" O60548 1 47438044-47440691 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.8" "Group enriched" "Detected in some" 4 "Distal enterocytes: 23.1;Enteroendocrine cells: 15.0;Intestinal goblet cells: 13.4;Paneth cells: 9.3;Undifferentiated cells: 13.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 3.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Podocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 4.0" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 26: Intestinal epithelial cells - Absorption" "unprognostic (5.10e-2)" "unprognostic (4.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (9.85e-3)" "unprognostic (2.81e-3)" "unprognostic (1.92e-1)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (4.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.79e-12)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (5.91e-2)" FOXI2 FLJ46831 ENSG00000186766 "Forkhead box I2" Q6ZQN5 10 127737185-127741183 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.9;kidney: 3.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Distal tubular cells: 3.1;granulocytes: 3.0;Salivary duct cells: 1.7;Squamous epithelial cells: 1.4" "Cancer enriched" "Detected in some" 6 "renal cancer: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 46: Granulocytes - Mast cell degranulation" "unprognostic (4.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (2.02e-1)" "unprognostic (1.06e-1)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "unprognostic (5.12e-3)" "unprognostic (4.71e-4)" "unprognostic (6.78e-3)" "prognostic favorable (4.23e-7)" "unprognostic (6.31e-3)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "unprognostic (1.65e-2)" FOXN3 "C14orf116, CHES1" ENSG00000053254 "Forkhead box N3" O00409 14 89124871-89619149 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 503.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059209 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA059209: AB_2683949" "unprognostic (1.69e-1)" "unprognostic (6.13e-3)" "unprognostic (2.08e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-2)" "unprognostic (2.03e-1)" "unprognostic (3.03e-1)" "unprognostic (1.34e-2)" "unprognostic (8.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.19e-1)" "prognostic favorable (9.58e-5)" "unprognostic (2.22e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (2.11e-1)" FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 10 "Hofbauer cells: 209.6;Kupffer cells: 392.0;Macrophages: 159.5;monocytes: 470.0" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Low cancer specificity" "Detected in many" "Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Skin - Macrophages" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" FRMPD1 "FRMD2, KIAA0967" ENSG00000070601 "FERM and PDZ domain containing 1" Q5SYB0 9 37650954-37746904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 68.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 47.6;Cone photoreceptor cells: 82.7;Inhibitory neurons: 23.8;Rod photoreceptor cells: 79.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Group enriched" "Detected in many" 4 "granulocytes: 3.2;NK-cells: 1.3" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042934 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 44: Photoreceptor cells - Visual perception" "HPA042934: AB_10960422" "unprognostic (6.41e-2)" "unprognostic (6.74e-3)" "unprognostic (1.25e-1)" "unprognostic (1.48e-3)" "unprognostic (4.04e-1)" "unprognostic (7.26e-2)" "unprognostic (1.45e-1)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (2.53e-3)" "unprognostic (2.63e-3)" "unprognostic (3.94e-2)" "unprognostic (1.12e-3)" "unprognostic (7.80e-2)" "unprognostic (4.41e-2)" "unprognostic (2.13e-2)" "unprognostic (5.91e-2)" FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 5.2;retina: 24.9" "Group enriched" "Detected in some" 14 "Astrocytes: 35.4;Bipolar cells: 49.9;Cone photoreceptor cells: 115.5;Early spermatids: 73.9;Endometrial ciliated cells: 58.9;Late spermatids: 123.2;Respiratory ciliated cells: 58.3;Rod photoreceptor cells: 97.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "prostate cancer: 2.5" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 56: Ciliated cells - Cilium assembly" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Group enriched" "Detected in many" 6 "Granulosa cells: 676.3;Skeletal myocytes: 213.8" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.5" "Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 397.1;Fibroblasts: 529.3;Leydig cells: 330.6;Peritubular cells: 269.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 385.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 49.4" "Kidney - Intercalated cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Approved "Nuclear membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" Mitochondria "Nuclear membrane" "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 38.6;Excitatory neurons: 42.9;Oligodendrocytes: 108.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.3;Leydig cells: 59.5;Muller glia cells: 60.1;Schwann cells: 246.7;Skeletal myocytes: 78.2" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 11: Non-specific - Transcription" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 104.2;Astrocytes: 33.5;Early spermatids: 29.5;Endothelial cells: 59.4;Fibroblasts: 52.5;Muller glia cells: 47.2;Oligodendrocytes: 65.4" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Macrophages, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.6;Excitatory neurons: 175.6;Inhibitory neurons: 180.1;Microglial cells: 47.4;Oligodendrocyte precursor cells: 43.3;Oligodendrocytes: 156.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.3" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA028757: AB_2294383, HPA074886: AB_2732270" "unprognostic (3.15e-2)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (3.40e-2)" "unprognostic (3.12e-2)" "unprognostic (1.19e-3)" "unprognostic (5.58e-3)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (6.88e-4)" "unprognostic (2.22e-1)" "unprognostic (3.23e-7)" "unprognostic (6.39e-2)" "unprognostic (6.60e-2)" "unprognostic (7.04e-3)" "unprognostic (1.78e-5)" GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 81.6;Hepatocytes: 18.0;Microglial cells: 19.2;Oligodendrocyte precursor cells: 21.7;Peritubular cells: 19.1" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.1;Neuroblastoma: 2.1" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.6;Endothelial cells: 72.9;monocytes: 41.4;Theca cells: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.3;Leukemia: 11.4" "Breast - Endothelial cells, Kidney - Endothelial cells" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "Plasma membrane" "HPA030101: AB_10601654, HPA062039: " "unprognostic (1.32e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.07e-3)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "unprognostic (5.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "prognostic favorable (9.29e-5)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.02e-3)" GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Group enriched" "Detected in many" 4 "monocytes: 38.2;NK-cells: 74.0;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 11.7;lymphoma: 11.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 505.4;Extravillous trophoblasts: 1288.6;Proximal tubular cells: 493.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: Non-specific - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.3;Cone photoreceptor cells: 58.6;Horizontal cells: 42.3;Rod photoreceptor cells: 53.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 62: Granulocytes - Innate immune response" "Cluster 35: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.9" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 28.7" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 109 "testis cancer: 77.2" "Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: BEWO - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 53.7;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in some" "granulocytes: 5.1;Intestinal goblet cells: 16.9;NK-cells: 16.2;Plasma cells: 7.6;T-cells: 16.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "Leukemia: 62.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB011197: AB_532302" "unprognostic (5.67e-4)" "unprognostic (8.67e-3)" "prognostic favorable (5.68e-5)" "unprognostic (4.88e-3)" "unprognostic (3.57e-2)" "unprognostic (5.86e-3)" "unprognostic (2.06e-1)" "unprognostic (3.87e-3)" "unprognostic (1.26e-3)" "unprognostic (4.47e-3)" "unprognostic (5.20e-2)" "unprognostic (1.72e-1)" "unprognostic (6.80e-6)" "unprognostic (2.63e-1)" "unprognostic (8.27e-2)" "unprognostic (3.97e-1)" "unprognostic (4.37e-2)" GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.2;Breast glandular cells: 27.4;Fibroblasts: 49.5;Hepatocytes: 34.8;Oligodendrocyte precursor cells: 87.1;Schwann cells: 25.2" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 60.9" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.0;Endothelial cells: 43.9;Fibroblasts: 68.4;Leydig cells: 34.1;Sertoli cells: 88.5;Smooth muscle cells: 86.6;Thymic epithelial cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cancer enhanced" "Detected in many" "Bile duct cancer: 23.1;testis cancer: 22.7" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 59: Fibroblasts - Metabolism" "Cluster 72: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Group enriched" "Detected in many" 6 "Adipocytes: 185.2;Endothelial cells: 224.0;Hofbauer cells: 119.8;Kupffer cells: 109.7;Macrophages: 128.3;monocytes: 122.4;NK-cells: 206.6;T-cells: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;pancreatic cancer: 9.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 7: NK-cells - Immune response regulation" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Group enriched" "Detected in some" 4 "Adipocytes: 19.9;Endothelial cells: 13.5;Macrophages: 5.7;NK-cells: 8.6;T-cells: 20.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Leukemia: 9.1" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 94.7;Endothelial cells: 90.8;Hofbauer cells: 28.5;Kupffer cells: 55.9;Macrophages: 25.6;monocytes: 29.0;NK-cells: 52.6;T-cells: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cancer enriched" "Detected in some" 7 "Leukemia: 16.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Group enriched" "Detected in many" 4 "Adipocytes: 65.2;Endothelial cells: 82.1;Kupffer cells: 66.5;Macrophages: 30.7;Microglial cells: 31.9;monocytes: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 1.5;lymphoma: 2.3;Myeloma: 1.2" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 19.0;Endothelial cells: 10.0;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" GJD2 "CX36, GJA9" ENSG00000159248 "Gap junction protein delta 2" Q9UKL4 15 34751032-34754998 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.9;pituitary gland: 7.5;retina: 21.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.7;Cone photoreceptor cells: 50.0;Horizontal cells: 10.9;Pancreatic endocrine cells: 5.2;Rod photoreceptor cells: 18.2" "Cancer enriched" "Detected in single" 32 "pancreatic cancer: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 3.5;Sarcoma: 1.3;testis cancer: 2.1" "Kidney - Intercalated cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "unprognostic (4.30e-2)" "unprognostic (2.87e-2)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 160.6" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 170.9" "Cancer enhanced" "Detected in many" "prostate cancer: 21.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 24 "NK-cells: 3.1;T-cells: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm Vesicles "HPA054808: AB_2682608, HPA059955: AB_2684178" "unprognostic (2.63e-2)" "unprognostic (9.77e-3)" "unprognostic (2.32e-2)" "unprognostic (2.20e-2)" "unprognostic (8.07e-2)" "unprognostic (1.54e-1)" "unprognostic (5.98e-2)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-1)" "unprognostic (4.73e-2)" "unprognostic (1.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.88e-3)" "unprognostic (1.01e-1)" GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.8;Extravillous trophoblasts: 39.5;Hepatocytes: 79.6;Oligodendrocyte precursor cells: 50.1;Syncytiotrophoblasts: 35.6" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 36.6" "Breast - Plasma cells, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" GLI1 GLI ENSG00000111087 "GLI family zinc finger 1" P08151 12 57459785-57472268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 11.1" "Group enriched" "Detected in some" 4 "Leydig cells: 35.1;Peritubular cells: 43.4;Sertoli cells: 13.8;Theca cells: 11.1" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.9" "Group enriched" "Detected in many" 6 "Bone cancer: 33.2;Brain cancer: 8.9;Rhabdoid: 21.5;Sarcoma: 8.5" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009460, HPA065172, HPA068903" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm Cytosol "CAB009460: AB_2111764, HPA065172: AB_2685427, HPA068903: AB_2732122" "unprognostic (4.97e-4)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (5.58e-3)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (9.00e-2)" "unprognostic (1.88e-1)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-8)" "unprognostic (4.59e-3)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-2)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 38.3;Fibroblasts: 9.8;Leydig cells: 25.1;Peritubular cells: 29.6;Theca cells: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 360.3;Excitatory neurons: 421.1;Proximal tubular cells: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 443.6" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" No No 92000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 285.0;Hepatocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 1: T-cells - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" GNA14 ENSG00000156049 "G protein subunit alpha 14" O95837 9 77423079-77648322 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Astrocytes: 212.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 95 "basophil: 27.3" "Lineage enriched" "Detected in single" 95 "granulocytes: 27.3" "Group enriched" "Detected in some" 7 "Bone cancer: 16.4;Rhabdoid: 4.4" "Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA048886: AB_2680544" "unprognostic (7.80e-3)" "unprognostic (1.10e-2)" "unprognostic (1.09e-2)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.53e-4)" "unprognostic (2.48e-6)" "unprognostic (6.35e-3)" "unprognostic (3.34e-1)" "unprognostic (9.04e-2)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (2.92e-2)" "unprognostic (1.04e-3)" "unprognostic (1.79e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-1)" GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 1816.6;Endothelial cells: 1155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 82.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 4: Platelets - Platelet activation" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" GP5 CD42d ENSG00000178732 "Glycoprotein V platelet" P40197 3 194394821-194398354 "CD markers, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.1" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA072646 Approved Cytosol NA NA 270000000 "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Cytosol "HPA072646: " "unprognostic (3.74e-2)" "unprognostic (3.40e-1)" "unprognostic (5.22e-2)" "unprognostic (2.96e-2)" "unprognostic (1.74e-2)" "unprognostic (1.35e-3)" "unprognostic (1.69e-3)" "unprognostic (1.68e-1)" "unprognostic (3.41e-1)" "unprognostic (2.80e-2)" "unprognostic (1.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (4.18e-2)" "unprognostic (3.14e-1)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.1;Extravillous trophoblasts: 70.5;Fibroblasts: 243.6;Muller glia cells: 71.1;Smooth muscle cells: 96.8;Syncytiotrophoblasts: 119.0" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in many" 5 "Gastric cancer: 93.1;liver cancer: 297.4;Rhabdoid: 106.3;testis cancer: 233.8" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 35: Liver cancer - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 14.9;Granulosa cells: 40.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 10.6" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.6;Horizontal cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 9: Neurons - Nervous system development" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enriched" "Detected in some" 4 "T-cells: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.3" "Lineage enriched" "Detected in many" 15 "T-cells: 110.3" "Group enriched" "Detected in some" 43 "Leukemia: 2.3;lymphoma: 7.6;Myeloma: 2.8" "Kidney - T-cells, Liver - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "B-cells: 34.3;NK-cells: 37.3;T-cells: 75.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 10.7;lymphoma: 3.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;lymphoid tissue: 38.9;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 88.7;Late spermatids: 242.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.3;NK-cells: 52.9;T-cells: 41.9" "Group enriched" "Detected in some" 13 "Leukemia: 6.8;lymphoma: 21.4" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013873 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" GPRC6A bA86F4.3 ENSG00000173612 "G protein-coupled receptor class C group 6 member A" Q5T6X5 6 116792085-116829083 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 11 "Salivary duct cells: 21.7" "Cancer enriched" "Detected in single" 11 "renal cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (9.16e-2)" "unprognostic (2.48e-1)" "unprognostic (4.38e-3)" GRAP ENSG00000154016 "GRB2 related adaptor protein" Q13588 17 19020656-19047011 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 37.5" "Cell type enhanced" "Detected in some" "Adipocytes: 11.0;B-cells: 18.6;Endothelial cells: 20.8;Hofbauer cells: 7.6;Microglial cells: 9.1;T-cells: 7.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 99.7;T-cells: 133.6" "Group enriched" "Detected in some" 10 "Leukemia: 14.3;lymphoma: 40.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046595, HPA066654" Uncertain Approved Centrosome NA NA 1400000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Centrosome "HPA046595: AB_10966385, HPA066654: AB_2685699" "unprognostic (3.02e-1)" "unprognostic (6.85e-2)" "unprognostic (6.25e-2)" "unprognostic (2.78e-2)" "unprognostic (3.43e-2)" "unprognostic (3.86e-6)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (4.03e-3)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (5.11e-2)" "unprognostic (2.67e-5)" "unprognostic (2.25e-1)" "unprognostic (1.57e-2)" "unprognostic (2.16e-1)" "unprognostic (5.77e-3)" GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Group enriched" "Detected in many" 7 "Erythroid cells: 28.7;granulocytes: 107.3;NK-cells: 43.6;T-cells: 56.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Cancer enriched" "Detected in some" 6 "Leukemia: 27.7" "Adipose visceral - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 4: Platelets - Platelet activation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 114.9;Squamous epithelial cells: 117.3;Syncytiotrophoblasts: 107.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 165.0;Esophageal cancer: 159.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Endothelial cells" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 31.4;liver: 26.3" "Cell type enriched" "Detected in many" 10 "Syncytiotrophoblasts: 316.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9" "Kidney - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" NA NA 12000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" GRTP1 "FLJ22474, TBC1D6" ENSG00000139835 "Growth hormone regulated TBC protein 1" Q5TC63 13 113324163-113364148 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.7;Distal enterocytes: 59.8;Proximal enterocytes: 68.0;Rod photoreceptor cells: 70.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046201 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 44: Photoreceptor cells - Visual perception" "HPA046201: AB_2679584" "unprognostic (5.31e-2)" "unprognostic (2.27e-3)" "unprognostic (1.94e-1)" "unprognostic (1.89e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (6.05e-2)" "unprognostic (1.30e-2)" "unprognostic (3.07e-3)" "prognostic favorable (1.50e-5)" "unprognostic (4.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.56e-2)" "unprognostic (4.50e-3)" GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.5;granulocytes: 43.5;Leydig cells: 149.6;Muller glia cells: 200.3;Peritubular cells: 127.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 11 "Bone cancer: 2.9;head and neck cancer: 1.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 68: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 68.1" "Cell type enhanced" "Detected in many" "Astrocytes: 46.8;Inhibitory neurons: 41.1;Rod photoreceptor cells: 44.8;Skeletal myocytes: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA044254: AB_10964747" "unprognostic (8.92e-2)" "unprognostic (6.94e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.71e-5)" "unprognostic (2.24e-1)" "unprognostic (3.35e-2)" "unprognostic (2.71e-3)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (6.26e-2)" "unprognostic (4.89e-3)" "unprognostic (3.31e-1)" "unprognostic (2.53e-1)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-3)" GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 127.3;Cardiomyocytes: 103.0;Inhibitory neurons: 69.6;Prostatic glandular cells: 173.1;Sertoli cells: 77.4;Smooth muscle cells: 150.6" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2" "Cancer enhanced" "Detected in many" "prostate cancer: 24.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674019-107018476 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;placenta: 17.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 348.3;Inhibitory neurons: 138.7;Oligodendrocyte precursor cells: 199.8;Smooth muscle cells: 83.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 42.8;Endometrial stromal cells: 45.2;Fibroblasts: 27.2;Late spermatids: 32.3;Oligodendrocytes: 57.9;Thymic epithelial cells: 44.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 29 "NK-cells: 1219.1;T-cells: 707.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cancer enriched" "Detected in some" 7 "lymphoma: 89.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" HAO1 "GOX, GOX1" ENSG00000101323 "Hydroxyacid oxidase 1" Q9UJM8 20 7882985-7940458 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 583 "liver: 607.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 308.1" "Cancer enriched" "Detected in some" 184 "liver cancer: 93.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049552, HPA072442" Enhanced Supported Vesicles NA NA 240000 "Cluster 62: Liver - Hemostasis" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA049552: AB_2680814, HPA072442: " "unprognostic (4.88e-2)" "unprognostic (2.87e-3)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 6.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.65e-4)" HDC ENSG00000140287 "Histidine decarboxylase" P19113 15 50241947-50265965 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 102.9;epididymis: 46.1" "Cell type enriched" "Detected in some" 15 "granulocytes: 233.9" "Cancer enhanced" "Detected in some" "breast cancer: 2.9;testis cancer: 2.7" "Region enriched" "Detected in many" 6 "hypothalamus: 102.9" "Immune cell enriched" "Detected in single" 2140 "basophil: 686.2" "Lineage enriched" "Detected in single" 2140 "granulocytes: 686.2" "Group enriched" "Detected in some" 9 "Leukemia: 44.2;Rhabdoid: 13.3" "Colon - Mast cells, Kidney - T-cells, Lung - Mast cells" "Region enriched" "Detected in many" 5 "hypothalamus: 43.9" "Group enriched" "Detected in some" 10 "hypothalamus: 16.5;midbrain: 4.2" HPA038891 Enhanced Approved "Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" "Nuclear bodies" "HPA038891: AB_10673231" "unprognostic (4.97e-2)" "unprognostic (7.42e-2)" "unprognostic (1.43e-4)" "unprognostic (1.08e-1)" "unprognostic (6.16e-2)" "unprognostic (3.93e-7)" "unprognostic (4.18e-5)" "unprognostic (8.79e-3)" "unprognostic (1.48e-1)" "unprognostic (8.46e-2)" "unprognostic (4.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (7.20e-2)" "unprognostic (9.78e-2)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 72.0" "Cell type enhanced" "Detected in many" "NK-cells: 38.9;Spermatocytes: 172.9;Spermatogonia: 117.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 19 "cerebellum: 9.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: RS4;11 - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favorable (2.56e-4)" "prognostic favorable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 9.3;testis: 13.8" "Cell type enhanced" "Detected in some" "Astrocytes: 49.3;Early spermatids: 23.7;Inhibitory neurons: 37.5;Oligodendrocyte precursor cells: 86.6;Spermatocytes: 58.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.8" "Kidney - Endothelial cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.1;Fibroblasts: 21.6;Inhibitory neurons: 22.0;Muller glia cells: 28.2;Smooth muscle cells: 62.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 105.6;Rhabdoid: 240.2" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 53: Connective tissue cells - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.0;dendritic cells: 27.7;Excitatory neurons: 47.0;Oligodendrocytes: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 32.3;Bipolar cells: 9.4;Excitatory neurons: 8.2;Inhibitory neurons: 11.9;Muller glia cells: 12.9;Oligodendrocyte precursor cells: 12.5;Thymic epithelial cells: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 66.8;Intestinal goblet cells: 87.1;Paneth cells: 97.7;Proximal enterocytes: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 80.6" "Breast - Breast glandular cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.6" "Group enriched" "Detected in many" 5 "Astrocytes: 81.3;Excitatory neurons: 216.2;Inhibitory neurons: 265.6;Microglial cells: 159.6;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 185.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005728 Approved Approved Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA005728: AB_10612117" "unprognostic (2.87e-3)" "unprognostic (2.38e-2)" "unprognostic (4.65e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (2.70e-3)" "unprognostic (3.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-8)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 38: Non-specific - mRNA processing" "Cluster 60: Proximal tubular cells - Absorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 21 "Endometrial stromal cells: 124.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 26: NCI-H716 - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enhanced" "Detected in some" "Club cells: 13.5;Distal enterocytes: 27.5;Enteroendocrine cells: 10.4;Fibroblasts: 7.0;Intestinal goblet cells: 9.7;Paneth cells: 10.3;Prostatic glandular cells: 37.1;Undifferentiated cells: 9.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 12.4" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 21.7;Distal enterocytes: 15.0;Endometrial stromal cells: 27.8;Enteroendocrine cells: 14.6;Intestinal goblet cells: 8.5;Paneth cells: 6.5;Undifferentiated cells: 8.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Kidney - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: Bone cancer - Transcription" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Club cells: 299.8;Distal enterocytes: 280.8;Extravillous trophoblasts: 889.9;granulocytes: 1505.8;Hepatocytes: 281.1;Proximal enterocytes: 478.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cancer enhanced" "Detected in many" "testis cancer: 121.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 46: Granulocytes - Mast cell degranulation" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 718.3;skeletal muscle: 453.0;tongue: 244.7" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 2420.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Myeloma: 6.3;Rhabdoid: 2.8;Sarcoma: 5.9" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004833 Enhanced "Intracellular and membrane" NA NA 100000 "Cluster 38: Heart - Muscle contraction" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA004833: AB_1079083" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (1.46e-2)" "unprognostic (4.94e-2)" "unprognostic (5.66e-2)" "unprognostic (9.75e-3)" "unprognostic (3.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.41e-3)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734949 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 968.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 637.6" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 5.6" "Lineage enriched" "Detected in single" 17 "T-cells: 5.6" "Cancer enhanced" "Detected in many" "Esophageal cancer: 19.5" "Colon - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced NA NA 110000 "Cluster 35: T-regs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA047729: AB_2680135" "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 141.8;Distal enterocytes: 585.7;Enteroendocrine cells: 135.1;Intestinal goblet cells: 249.2;Paneth cells: 276.6;Proximal enterocytes: 251.6;Syncytiotrophoblasts: 167.7" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 14.2;prostate cancer: 13.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Supported Vesicles NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Vesicles "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" HSPA4L "APG-1, HSPH3, Osp94" ENSG00000164070 "Heat shock protein family A (Hsp70) member 4 like" O95757 4 127781821-127840733 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.7" "Cell type enhanced" "Detected in many" "Early spermatids: 366.0;Late spermatids: 925.2;Spermatocytes: 175.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB034450, HPA039149, HPA061446" Enhanced Approved Centrosome,Cytosol NA NA 1000000 "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 6: Late spermatids - Spermatogenesis" "Centrosome, Cytosol" "CAB034450: AB_2119823, HPA039149: AB_2676366, HPA061446: AB_2684520" "unprognostic (6.66e-2)" "unprognostic (2.39e-1)" "unprognostic (5.33e-2)" "unprognostic (9.40e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (1.23e-3)" "unprognostic (2.41e-1)" "unprognostic (3.90e-1)" "unprognostic (2.38e-4)" "unprognostic (1.40e-2)" "unprognostic (3.28e-1)" "prognostic favorable (3.80e-9)" "unprognostic (8.53e-2)" "unprognostic (1.56e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (6.78e-4)" HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 179.3;Fibroblasts: 146.6;Leydig cells: 266.6;Peritubular cells: 222.4;Skeletal myocytes: 405.8;Smooth muscle cells: 178.7;Theca cells: 235.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 61.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nuclear speckles,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "Mitochondria, Cytosol" "Nuclear speckles" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" HTATSF1 TAT-SF1 ENSG00000102241 "HIV-1 Tat specific factor 1" O43719 X 136497079-136512346 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 274.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000504 Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA000504: AB_10752094" "unprognostic (3.56e-2)" "prognostic favorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (6.72e-2)" "unprognostic (3.70e-1)" "unprognostic (3.32e-3)" "unprognostic (3.27e-1)" "unprognostic (2.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.73e-2)" "unprognostic (3.37e-2)" "prognostic favorable (8.13e-8)" "unprognostic (7.12e-2)" "unprognostic (2.67e-2)" "unprognostic (2.25e-2)" "unprognostic (4.05e-1)" HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 17.4;cervix: 21.5;endometrium 1: 18.8;smooth muscle: 16.8" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 16.7;Microglial cells: 4.6;Peritubular cells: 4.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 1.8;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.8;T-cells: 1.0" "Group enriched" "Detected in some" 5 "Rhabdoid: 18.0;skin cancer: 12.9" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "HPA012867: AB_1856710, HPA063658: AB_2685079" "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 182.2;dendritic cells: 70.3;Early spermatids: 85.7;Hofbauer cells: 63.7;Late spermatids: 72.5;Spermatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 31.5;lymphoma: 38.8;Myeloma: 32.1" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 351.0;Endothelial cells: 214.4;monocytes: 114.0;NK-cells: 87.6;Plasma cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bile duct cancer: 27.7;Leukemia: 72.6;lymphoma: 49.9;Myeloma: 72.4;ovarian cancer: 30.4;pancreatic cancer: 44.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 146.4;Hepatocytes: 177.1;monocytes: 254.2;NK-cells: 246.5;Plasma cells: 138.3;T-cells: 179.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Group enriched" "Detected in all" 6 "Leukemia: 98.4;lymphoma: 73.3;Myeloma: 127.4" "Adipose subcutaneous - T-cells, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Lung - Neutrophil_2, Prostate - T-cells" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 10 "T-cells: 89.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Cancer enhanced" "Detected in some" "Leukemia: 2.4;lymphoma: 3.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 371.4;NK-cells: 400.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3562.2;Distal enterocytes: 3300.8;Endothelial cells: 1616.6;Intestinal goblet cells: 2142.6;Paneth cells: 1898.0;Proximal enterocytes: 3146.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 997.5" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 74: Pancreatic cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 911.0" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Gastric cancer: 32.4;liver cancer: 84.6;ovarian cancer: 103.1;pancreatic cancer: 51.0" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 538.2;Fibroblasts: 1434.1;Leydig cells: 997.0;Peritubular cells: 1559.1;Sertoli cells: 500.3;Smooth muscle cells: 554.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11591.8;Peritubular cells: 12013.4;Sertoli cells: 3618.3;Smooth muscle cells: 3737.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney cancer: 772.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 30300000 190000000 "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Cell type enriched" "Detected in many" 10 "Plasma cells: 70370.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cancer enriched" "Detected in some" 26 "Myeloma: 2211.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" IGHD3-22 IGHD322 ENSG00000211911 "Immunoglobulin heavy diversity 3-22" 14 105886031-105886061 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.6;lymphoid tissue: 2.7;stomach 1: 3.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 48.9" "Lineage enriched" "Detected in many" 7 "B-cells: 48.9" "Cancer enriched" "Detected in single" 10 "Leukemia: 1.6" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "unprognostic (4.12e-1)" "unprognostic (1.53e-1)" IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 31 "B-cells: 2040.6;Plasma cells: 6710.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Cancer enriched" "Detected in some" 10 "Myeloma: 1216.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Cell type enriched" "Detected in some" 11 "Plasma cells: 4718.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Cancer enriched" "Detected in some" 4 "Myeloma: 53.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 25 "B-cells: 1189.2;Plasma cells: 2469.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 29 "lymphoma: 76.6;Myeloma: 22.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Cell type enhanced" "Detected in some" "B-cells: 429.3;Basal keratinocytes: 123.6;Plasma cells: 568.0;T-cells: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Group enriched" "Detected in some" 38 "lymphoma: 133.9;Myeloma: 34.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 156 "Plasma cells: 15.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Group enriched" "Detected in some" 14 "lymphoma: 24.6;Myeloma: 56.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 67 "Plasma cells: 31.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cancer enriched" "Detected in some" 13 "lymphoma: 17.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 34: Plasma cells - Humoral immune response" IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 23 "Plasma cells: 9683.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cancer enriched" "Detected in single" 127 "lymphoma: 44.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 24 "Plasma cells: 1122.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 31 "Plasma cells: 8505.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Myeloma: 18.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Cell type enriched" "Detected in some" 26 "Plasma cells: 59.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 153 "Plasma cells: 228.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.6" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Cell type enriched" "Detected in some" 190 "Plasma cells: 7357.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 30.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Cell type enriched" "Detected in some" 16 "Plasma cells: 123.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 228 "Plasma cells: 7582.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cancer enriched" "Detected in some" 1612 "Myeloma: 2170.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 127 "Plasma cells: 43.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 70 "Plasma cells: 1747.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cancer enriched" "Detected in single" 7 "Myeloma: 1.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 167 "Plasma cells: 697.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cancer enhanced" "Detected in single" "Leukemia: 1.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3489.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 26 "lymphoma: 88.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 11756.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cancer enriched" "Detected in some" 24 "Myeloma: 787.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 148 "Plasma cells: 10222.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cancer enriched" "Detected in some" 6 "Myeloma: 299.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 99 "Plasma cells: 1565.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cancer enhanced" "Detected in some" "Leukemia: 4.3;lymphoma: 6.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Cell type enriched" "Detected in single" 31 "Plasma cells: 3.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 660.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 81 "Plasma cells: 4032.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Group enriched" "Detected in some" 140 "lymphoma: 22.9;Myeloma: 23.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 75 "Plasma cells: 666.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Group enriched" "Detected in some" 99 "Leukemia: 8.5;lymphoma: 24.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 198 "Plasma cells: 1621.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cancer enriched" "Detected in some" 4 "lymphoma: 31.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 145 "Plasma cells: 13920.0" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Group enriched" "Detected in some" 299 "Leukemia: 223.7;lymphoma: 108.5;Myeloma: 186.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Cell type enriched" "Detected in single" 13 "Plasma cells: 1.3" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cancer enriched" "Detected in single" 140 "lymphoma: 14.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" IGHV3OR16-8 IGHV3/OR16-8 ENSG00000271130 "Immunoglobulin heavy variable 3/OR16-8 (non-functional)" 16 33009175-33009620 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 32.0;lymphoid tissue: 49.4;stomach 1: 32.9;urinary bladder: 40.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "memory B-cell: 7.3" "Lineage enriched" "Detected in single" 74 "B-cells: 7.3" "Cancer enriched" "Detected in single" 42 "Myeloma: 4.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (2.58e-4)" "unprognostic (3.25e-2)" "unprognostic (9.53e-3)" "unprognostic (1.56e-1)" "unprognostic (2.43e-4)" "unprognostic (1.31e-1)" "unprognostic (4.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-7)" "unprognostic (2.24e-2)" "unprognostic (4.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.16e-2)" IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 175 "Plasma cells: 270.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Cancer enriched" "Detected in single" 10 "Myeloma: 3.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 177 "Plasma cells: 12683.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 53 "lymphoma: 256.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 176 "Plasma cells: 8419.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cancer enriched" "Detected in some" 9 "lymphoma: 98.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 38 "Plasma cells: 1873.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cancer enriched" "Detected in single" 45 "lymphoma: 20.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 146 "Plasma cells: 1746.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 19 "B-cells: 31159.1;Plasma cells: 107120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Cancer enriched" "Detected in many" 8 "Myeloma: 32460.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cancer enriched" "Detected in many" 7 "Myeloma: 2637.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in some" 10 "lymphoma: 295.8;Myeloma: 182.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 18 "lymphoma: 255.6;Myeloma: 432.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cancer enriched" "Detected in many" 12 "Myeloma: 5675.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Group enriched" "Detected in some" 15 "lymphoma: 390.0;Myeloma: 390.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 226 "Plasma cells: 7657.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cancer enriched" "Detected in single" 4 "Myeloma: 2.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 11644.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cancer enriched" "Detected in single" 1009 "Myeloma: 161.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 136 "Plasma cells: 4201.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 66 "Plasma cells: 1039.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cancer enriched" "Detected in some" 5 "lymphoma: 214.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 154 "Plasma cells: 9939.2" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cancer enriched" "Detected in some" 10 "Myeloma: 166.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 189 "Plasma cells: 27048.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cancer enriched" "Detected in some" 8 "Myeloma: 919.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Group enriched" "Detected in some" 30 "lymphoma: 4.2;Myeloma: 1.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 29 "Plasma cells: 313.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4448.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cancer enriched" "Detected in single" 8 "lymphoma: 5.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 913 "Plasma cells: 4001.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cancer enriched" "Detected in single" 33 "Myeloma: 22.0" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 288 "Plasma cells: 4205.7" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Cancer enriched" "Detected in many" 30 "Myeloma: 6429.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 25.3" "Cell type enriched" "Detected in single" 39 "Plasma cells: 4.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 41000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 54 "Plasma cells: 335.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cancer enriched" "Detected in single" 4 "Myeloma: 2.8" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 161 "Plasma cells: 1378.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cancer enriched" "Detected in some" 146 "lymphoma: 184.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 296 "Plasma cells: 16045.5" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cancer enriched" "Detected in some" 5 "lymphoma: 156.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 26 "Plasma cells: 380.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Group enriched" "Detected in some" 27 "lymphoma: 7.8;Myeloma: 4.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 108 "Plasma cells: 19383.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cancer enriched" "Detected in some" 22 "Myeloma: 5294.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 136 "Plasma cells: 44838.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 308 "lymphoma: 325.1;Myeloma: 1137.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 407 "Plasma cells: 1863.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cancer enriched" "Detected in many" 241 "Myeloma: 3594.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 61 "Plasma cells: 480.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cancer enriched" "Detected in some" 455 "Myeloma: 2694.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 521 "Plasma cells: 95.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Group enriched" "Detected in some" 25 "lymphoma: 1.9;Myeloma: 3.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 37 "Plasma cells: 31810.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cancer enriched" "Detected in some" 8 "lymphoma: 466.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 94 "Plasma cells: 1098.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cancer enriched" "Detected in single" 12 "Myeloma: 1.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cancer enriched" "Detected in many" 129 "Myeloma: 17348.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Cell type enriched" "Detected in many" 4 "Plasma cells: 55429.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Cancer enriched" "Detected in many" 13 "Myeloma: 16187.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 16 "lymphoma: 274.0;Myeloma: 867.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 270 "Plasma cells: 31725.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cancer enriched" "Detected in some" 38 "Myeloma: 3258.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 12 "Plasma cells: 10227.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cancer enriched" "Detected in some" 363 "Myeloma: 3377.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 19 "Plasma cells: 242.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cancer enriched" "Detected in single" 389 "Myeloma: 110.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 163 "Plasma cells: 44094.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cancer enriched" "Detected in many" 14 "Myeloma: 6603.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 219 "Plasma cells: 2096.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Cancer enriched" "Detected in some" 3236 "Myeloma: 8855.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 86 "Plasma cells: 8217.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cancer enriched" "Detected in some" 68 "Myeloma: 5175.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 82 "Plasma cells: 3934.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Cancer enriched" "Detected in many" 71 "Myeloma: 5051.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 70 "Plasma cells: 37887.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cancer enriched" "Detected in some" 5 "lymphoma: 193.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 94 "Plasma cells: 1131.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cancer enriched" "Detected in many" 150 "Myeloma: 4413.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 91 "Plasma cells: 843.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 36 "Leukemia: 236.9;lymphoma: 904.2" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 60 "Plasma cells: 5699.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cancer enriched" "Detected in single" 519 "lymphoma: 248.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 78 "Plasma cells: 4681.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Cancer enriched" "Detected in single" 11 "Myeloma: 1.6" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 172 "Plasma cells: 9060.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Group enriched" "Detected in some" 24 "lymphoma: 41.1;Myeloma: 31.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA028862 Supported "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA028862: " "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 51 "Plasma cells: 956.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 40: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 231 "Plasma cells: 6180.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 34: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 7 "Plasma cells: 41.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Cancer enriched" "Detected in single" 131 "lymphoma: 50.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 35.6;Exocrine glandular cells: 33.8;Fibroblasts: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 65: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 308.6;Glandular and luminal cells: 316.8;Langerhans cells: 224.1;Prostatic glandular cells: 296.8;Thymic epithelial cells: 249.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" IL22RA1 "CRF2-9, IL22R" ENSG00000142677 "Interleukin 22 receptor subunit alpha 1" Q8N6P7 1 24119771-24143140 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 199.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 16.4;Intestinal goblet cells: 15.8;Proximal enterocytes: 36.3;Respiratory ciliated cells: 14.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.68e-3)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-3)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (7.63e-2)" "unprognostic (1.72e-3)" "unprognostic (2.28e-1)" "unprognostic (4.78e-3)" "unprognostic (1.05e-2)" "unprognostic (2.57e-1)" "unprognostic (2.63e-1)" "unprognostic (1.64e-2)" IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 97.8;NK-cells: 304.7;T-cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cancer enriched" "Detected in some" 10 "lymphoma: 85.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 112.9;dendritic cells: 93.7;Distal enterocytes: 87.2;Langerhans cells: 151.6;NK-cells: 284.8;Plasma cells: 91.0;Proximal enterocytes: 80.8;T-cells: 197.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 203.1;lymphoma: 129.5;Myeloma: 347.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA046641 Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Plasma membrane" "Endoplasmic reticulum" "HPA046641: AB_2679733" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 72.7;granulocytes: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 135.3" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" INSYN1 "C15orf59, LOC388135, MGC131524" ENSG00000205363 "Inhibitory synaptic factor 1" Q2T9L4 15 73735458-73753351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.6;heart muscle: 48.5" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Bipolar cells: 13.1;Cardiomyocytes: 8.3;Excitatory neurons: 4.6;Horizontal cells: 13.5;Inhibitory neurons: 9.6;Muller glia cells: 7.4" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041563 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 65: Breast cancer - Unknown function" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Cytosol" "HPA041563: AB_10794670" "unprognostic (2.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.85e-2)" "unprognostic (2.36e-1)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (8.36e-2)" "unprognostic (2.67e-4)" "unprognostic (2.67e-2)" "prognostic favorable (5.38e-9)" "unprognostic (4.98e-2)" "unprognostic (5.19e-2)" "unprognostic (2.46e-4)" "unprognostic (1.20e-3)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 169.2;Early spermatids: 44.6;Peritubular cells: 86.8;Sertoli cells: 35.9;Smooth muscle cells: 100.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108334 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 60.3;lymphoid tissue: 202.8" "Cell type enhanced" "Detected in many" "B-cells: 69.0;Microglial cells: 67.5;monocytes: 57.2;NK-cells: 80.8;Plasma cells: 52.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 210.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Leukemia: 186.1;lymphoma: 341.9;Myeloma: 121.8" "Breast - Endothelial cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" IRX3 IRX-1 ENSG00000177508 "Iroquois homeobox 3" P78415 16 54283304-54286787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 89.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 134.0;Basal prostatic cells: 176.3;Breast glandular cells: 124.5;Breast myoepithelial cells: 82.0;Glandular and luminal cells: 112.7;Respiratory ciliated cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 35.6" "Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066576 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm Cytosol "HPA066576: " "unprognostic (4.21e-3)" "unprognostic (4.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" "unprognostic (9.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (3.15e-2)" "unprognostic (5.40e-2)" "unprognostic (2.39e-1)" "unprognostic (8.20e-2)" "unprognostic (1.25e-1)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 194.0;Fibroblasts: 156.8;Leydig cells: 219.8;Peritubular cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" ISX RAXLX ENSG00000175329 "Intestine specific homeobox" Q2M1V0 22 35066136-35087387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "intestine: 37.5" "Group enriched" "Detected in some" 33 "Distal enterocytes: 32.2;Enteroendocrine cells: 23.3;Intestinal goblet cells: 20.2;Paneth cells: 24.4;Proximal enterocytes: 29.8;Undifferentiated cells: 17.2" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 10.8;colorectal cancer: 4.9" "Colon - Colon enterocytes, Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA060328 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "Nuclear bodies" "HPA060328: AB_2684254" "unprognostic (5.02e-2)" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "unprognostic (3.33e-1)" "unprognostic (3.86e-1)" "unprognostic (2.55e-1)" ITFG2 "FGGAP1, MDS028" ENSG00000111203 "Integrin alpha FG-GAP repeat containing 2" Q969R8 12 2812622-2859791 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038664, HPA038665" Uncertain Uncertain "Endoplasmic reticulum" NA No "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Endoplasmic reticulum" "HPA038664: AB_10672722, HPA038665: AB_2676138" "unprognostic (5.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (2.96e-1)" "unprognostic (2.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-2)" "unprognostic (3.64e-2)" "unprognostic (1.60e-2)" "unprognostic (4.36e-2)" "unprognostic (5.05e-3)" "unprognostic (8.40e-2)" "unprognostic (2.60e-1)" "unprognostic (4.24e-1)" "unprognostic (5.89e-1)" "unprognostic (4.35e-2)" "unprognostic (7.43e-2)" ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.3;endometrium 1: 53.1;smooth muscle: 25.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 9.3;Cardiomyocytes: 12.6;Excitatory neurons: 13.1;Fibroblasts: 27.8;Horizontal cells: 14.7;Microglial cells: 18.2;Peritubular cells: 10.1;Smooth muscle cells: 10.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 33.8" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 7.3;spinal cord: 2.1" HPA051813 Uncertain NA NA 260000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA051813: AB_2681622" "unprognostic (4.85e-2)" "unprognostic (3.51e-1)" "unprognostic (6.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (9.29e-3)" "unprognostic (6.63e-2)" "unprognostic (5.68e-3)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (8.38e-3)" "unprognostic (2.28e-4)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 282.9;Ductal cells: 117.7;Exocrine glandular cells: 114.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.6;monocytes: 151.0;NK-cells: 195.1;T-cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 125 "Leukemia: 74.5;lymphoma: 40.6;Myeloma: 51.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in some" "granulocytes: 57.7;Hofbauer cells: 71.9;Langerhans cells: 143.3;Macrophages: 114.2;Microglial cells: 54.7;monocytes: 272.2;NK-cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;lymphoma: 9.2" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Liver - Neutrophils, Skeletal muscle - Neutrophils, Thyroid - T-cells" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871, CAB080214" Enhanced Supported "Vesicles,Plasma membrane" NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Vesicles, Plasma membrane" "CAB004458: AB_626859, CAB072871: AB_2665723, CAB080214: , HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 760.4;Kupffer cells: 784.3;Langerhans cells: 320.5;Macrophages: 522.0;monocytes: 733.4;NK-cells: 698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 67.2;Leukemia: 198.4;lymphoma: 74.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Cell type enhanced" "Detected in some" "granulocytes: 29.4;NK-cells: 75.1;Serous glandular cells: 22.9;T-cells: 127.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 44 "Leukemia: 7.3;lymphoma: 5.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 263.6;Endometrial ciliated cells: 189.9;Smooth muscle cells: 165.8;Squamous epithelial cells: 339.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 72: Smooth muscle cells - ECM organization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 7 "dendritic cells: 275.0;Hofbauer cells: 105.6;Kupffer cells: 135.5;Langerhans cells: 331.4;Macrophages: 148.9;monocytes: 205.6;T-cells: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Group enriched" "Detected in some" 10 "Leukemia: 6.4;lymphoma: 15.9" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 12 "Plasma cells: 72765.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cancer enriched" "Detected in many" 13 "Myeloma: 13933.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 82.7;monocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" JPH1 JP-1 ENSG00000104369 "Junctophilin 1" Q9HDC5 8 74234700-74321540 "Human disease related genes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 237.4;tongue: 106.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 33.5;Excitatory neurons: 81.0;Inhibitory neurons: 49.2;Skeletal myocytes: 153.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 20.9" "Kidney - Podocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008996, HPA009413, CAB013461" Enhanced Enhanced Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "CAB013461: , HPA008996: AB_1852023, HPA009413: AB_1079163" "unprognostic (2.91e-3)" "unprognostic (3.01e-1)" "unprognostic (8.85e-2)" "unprognostic (8.73e-6)" "unprognostic (2.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.63e-2)" "prognostic favorable (5.77e-5)" "unprognostic (8.97e-2)" "unprognostic (1.30e-1)" "unprognostic (2.38e-1)" "unprognostic (5.99e-2)" "unprognostic (9.80e-2)" "unprognostic (6.87e-2)" "unprognostic (3.03e-1)" "unprognostic (4.88e-2)" "unprognostic (1.08e-2)" KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.6;Gastric mucus-secreting cells: 34.0;Intestinal goblet cells: 60.9;Proximal enterocytes: 73.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 27.8" "Kidney - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;retina: 18.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9688.5;Inhibitory neurons: 1921.9;Oligodendrocyte precursor cells: 4956.5" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Kidney - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 58: Brain - Synaptic function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" KCNJ1 "Kir1.1, ROMK1" ENSG00000151704 "Potassium inwardly rectifying channel subfamily J member 1" P48048 11 128836315-128867373 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Bartter syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 117 "kidney: 198.0" "Group enriched" "Detected in some" 93 "Collecting duct cells: 23.6;Distal tubular cells: 80.9" "Cancer enriched" "Detected in some" 7 "renal cancer: 3.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA026962 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 16: Non-specific - RNA binding" "HPA026962: AB_10601934" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-1)" "unprognostic (2.44e-2)" "unprognostic (6.47e-2)" "unprognostic (2.78e-1)" "unprognostic (6.05e-2)" "unprognostic (4.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (7.81e-3)" KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 305.2;Inhibitory neurons: 421.9" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.3" "Adipose subcutaneous - Smooth muscle cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4;kidney: 37.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.9;Cytotrophoblasts: 28.5;Distal enterocytes: 36.2;Proximal enterocytes: 56.4;Salivary duct cells: 35.5;Syncytiotrophoblasts: 41.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 50: Enterocytes - Absorption" Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" KHDRBS2 "MGC26664, SLM-1, SLM1" ENSG00000112232 "KH RNA binding domain containing, signal transduction associated 2" Q5VWX1 6 61679961-62286225 "Predicted intracellular proteins" "mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;retina: 4.0;thyroid gland: 4.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1402.3;Inhibitory neurons: 704.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.6" "Region enhanced" "Detected in many" "cerebral cortex: 5.8" "Group enriched" "Detected in some" 13 "memory B-cell: 5.9;naive B-cell: 6.9;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 12 "B-cells: 6.9;dendritic cells: 1.9" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000500, HPA029392" Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA000500: AB_1079184, HPA029392: AB_10600816" "unprognostic (6.98e-2)" "unprognostic (1.21e-1)" "unprognostic (3.06e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-3)" "unprognostic (4.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.25e-4)" "unprognostic (1.45e-2)" "unprognostic (2.19e-5)" "unprognostic (5.52e-2)" "unprognostic (4.54e-2)" "unprognostic (6.24e-3)" "unprognostic (1.15e-1)" KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.8;Bipolar cells: 3.4;Fibroblasts: 6.5;Horizontal cells: 9.6;Skeletal myocytes: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.5" "Kidney - T-cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" KIAA1191 "FLJ21022, p33MONOX, p60MONOX" ENSG00000122203 KIAA1191 Q96A73 5 176346062-176361807 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 245.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044701, HPA048145" Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 7: Kidney - Transmembrane transport" "Cluster 57: Non-specific - Translation" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "HPA044701: AB_2679053, HPA048145: AB_2680283" "unprognostic (7.59e-3)" "unprognostic (1.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.94e-2)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.46e-1)" "unprognostic (1.48e-2)" "unprognostic (4.39e-1)" "unprognostic (7.10e-2)" "unprognostic (8.93e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.94e-5)" "unprognostic (5.02e-3)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.73e-2)" KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Astrocytes: 21.8;Bipolar cells: 26.6;Cone photoreceptor cells: 34.5;Late spermatids: 84.4;monocytes: 22.6;NK-cells: 21.9;Rod photoreceptor cells: 28.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Group enriched" "Detected in many" 8 "Leukemia: 30.4;lymphoma: 35.2;Myeloma: 74.8" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 51: Late spermatids - Spermatogenesis" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" KIF7 JBTS12 ENSG00000166813 "Kinesin family member 7" Q2M1P5 15 89608789-89655467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Repressor" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 13.9;Leydig cells: 5.8;Oligodendrocyte precursor cells: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043145 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA043145: AB_10969200" "unprognostic (9.52e-2)" "unprognostic (1.07e-1)" "unprognostic (2.74e-3)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.81e-1)" "unprognostic (3.67e-3)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.81e-2)" "unprognostic (3.54e-1)" "unprognostic (4.01e-2)" "unprognostic (3.13e-1)" "unprognostic (1.39e-8)" "unprognostic (2.67e-1)" "unprognostic (2.92e-2)" "unprognostic (4.84e-2)" "unprognostic (1.66e-1)" KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Group enriched" "Detected in some" 4 "Prostatic glandular cells: 41.0;Proximal tubular cells: 108.6" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;Kidney cancer: 2.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 89.7;Oligodendrocytes: 151.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 182.4;Microglial cells: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 1674.3" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Gastric cancer: 7.0;liver cancer: 9.1" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" KRTAP5-8 "KRTAP5-2, KRTAP5.8, UHSKerB" ENSG00000241233 "Keratin associated protein 5-8" O75690 11 71538025-71539209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 6.0;skin 1: 7.6" "Group enriched" "Detected in some" 12 "Distal tubular cells: 6.2;Schwann cells: 4.0" "Cancer enhanced" "Detected in single" "renal cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 41: Non-specific - Cilium assembly" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "unprognostic (9.72e-2)" "unprognostic (8.49e-2)" "unprognostic (9.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-2)" "unprognostic (1.99e-1)" "unprognostic (6.92e-2)" "unprognostic (2.89e-2)" "unprognostic (2.42e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.21e-3)" KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 174.7;Ionocytes: 235.2;Langerhans cells: 296.6;monocytes: 242.4;Syncytiotrophoblasts: 205.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 118.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 146.7;granulocytes: 66.1;Hofbauer cells: 191.3;Kupffer cells: 83.7;Macrophages: 128.4;monocytes: 80.2;NK-cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 4.3;Myeloma: 2.5" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 129.4;Basal respiratory cells: 107.2;Distal enterocytes: 83.3;Gastric mucus-secreting cells: 123.4;Paneth cells: 85.5;Salivary duct cells: 76.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 149.4" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.1;granulocytes: 129.5;Hofbauer cells: 108.1;Kupffer cells: 95.4;Langerhans cells: 105.7;Macrophages: 84.5;monocytes: 53.3;NK-cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 200.2;lymphoma: 105.0" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 71.5;Basal respiratory cells: 41.1;Endothelial cells: 45.3;Peritubular cells: 57.2;Thymic epithelial cells: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 123 "dendritic cells: 11.2;T-cells: 13.4" "Cancer enhanced" "Detected in many" "Brain cancer: 73.4" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 489.4;Smooth muscle cells: 279.2;T-cells: 198.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.4;MAIT T-cell: 110.2;memory B-cell: 92.0;memory CD4 T-cell: 83.8;memory CD8 T-cell: 86.1;naive B-cell: 123.0;naive CD4 T-cell: 140.2;naive CD8 T-cell: 124.6;T-reg: 89.2" "Group enriched" "Detected in all" 7 "B-cells: 123.0;T-cells: 140.2" "Cancer enhanced" "Detected in all" "Bone cancer: 152.8" "Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA034669: AB_10600820" "unprognostic (2.13e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (4.77e-3)" "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (3.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.25e-2)" "unprognostic (7.91e-3)" "unprognostic (1.67e-1)" LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 392.6" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 7.8;thyroid cancer: 2.8" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 29: Hepatocytes - Metabolism" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "NK-cells: 191.1;T-cells: 253.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in many" 5 "Leukemia: 91.2;lymphoma: 54.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Excitatory neurons: 1296.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cancer enriched" "Detected in many" 6 "Bone cancer: 30.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" LDLRAP1 "ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705" ENSG00000157978 "Low density lipoprotein receptor adaptor protein 1" Q5SW96 1 25543606-25568886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Atherosclerosis, Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "NK-cells: 39.5;T-cells: 107.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003705, HPA050358" Uncertain Approved Microtubules NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 2: T-cells - T-cell receptor" Microtubules "CAB003705: AB_425923, HPA050358: AB_2681103" "unprognostic (2.52e-2)" "unprognostic (5.39e-3)" "unprognostic (7.49e-3)" "unprognostic (4.12e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-2)" "unprognostic (1.70e-2)" "unprognostic (7.27e-3)" "unprognostic (4.79e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-3)" "unprognostic (9.96e-2)" "unprognostic (6.49e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.74e-2)" "unprognostic (4.24e-1)" LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 92.8;Late spermatids: 54.7;Spermatocytes: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 882.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 19: Macrophages - Innate immune response" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" LGALS8 PCTA-1 ENSG00000116977 "Galectin 8" O00214 1 236518000-236552981 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.4;Late spermatids: 249.5;Syncytiotrophoblasts: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 118.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012734, HPA030491" Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 6: Late spermatids - Spermatogenesis" "Plasma membrane" "HPA012734: AB_2668720, HPA030491: AB_10602345" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (4.71e-3)" "unprognostic (3.93e-2)" "prognostic favorable (9.40e-4)" "unprognostic (9.96e-2)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.93e-7)" "unprognostic (1.41e-1)" "unprognostic (1.57e-1)" "unprognostic (3.15e-2)" "unprognostic (8.21e-2)" LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 44.9;Excitatory neurons: 17.5;Horizontal cells: 17.9;Inhibitory neurons: 23.2;Melanocytes: 78.4;Oligodendrocytes: 55.2" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 31 "skin cancer: 14.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Uncertain Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 41: Alveolar cells - Lung function" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "dendritic cells: 117.4;Hofbauer cells: 64.1;Kupffer cells: 246.4;Langerhans cells: 84.7;Macrophages: 119.5;monocytes: 561.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 188.5;Hofbauer cells: 139.3;Kupffer cells: 84.7;Macrophages: 91.4;monocytes: 45.8;Plasma cells: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cancer enriched" "Detected in some" 5 "Myeloma: 25.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" LIN52 C14orf46 ENSG00000205659 "Lin-52 DREAM MuvB core complex component" Q52LA3 14 74084796-74201235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.8;Inhibitory neurons: 63.9;Oligodendrocyte precursor cells: 57.8;Oligodendrocytes: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000900, HPA001777" Uncertain Approved "Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Nuclear speckles" "HPA000900: AB_2135058, HPA001777: AB_2666431" "unprognostic (2.34e-2)" "unprognostic (6.51e-3)" "unprognostic (1.86e-1)" "unprognostic (1.94e-1)" "unprognostic (7.90e-3)" "prognostic favorable (6.60e-4)" "prognostic unfavorable (6.08e-5)" "unprognostic (2.48e-3)" "unprognostic (9.34e-2)" "unprognostic (8.65e-2)" "unprognostic (1.39e-3)" "unprognostic (3.18e-1)" "unprognostic (1.74e-3)" "unprognostic (1.20e-2)" "unprognostic (8.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.04e-1)" LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 108.4;Endothelial cells: 156.7;Erythroid cells: 86.4;monocytes: 120.3" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cancer enriched" "Detected in many" 4 "Leukemia: 47.0" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" LMOD1 "1D, 64kD, D1" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 513.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 194.7;Leydig cells: 127.6;Peritubular cells: 278.4;Sertoli cells: 110.6;Smooth muscle cells: 324.7" "Cancer enhanced" "Detected in all" "prostate cancer: 43.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "HPA028325: AB_10600300, HPA028435: AB_10602180, HPA030097: AB_10601223" "unprognostic (3.84e-2)" "unprognostic (5.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (5.64e-1)" "unprognostic (6.35e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.73e-2)" "unprognostic (3.51e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (1.15e-2)" LRCOL1 ENSG00000204583 "Leucine rich colipase like 1" A6NCL2 12 132603150-132610582 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "epididymis: 50.1" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 27.8" "Group enriched" "Detected in some" 4 "endometrial cancer: 0.8;liver cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "unprognostic (5.09e-3)" "unprognostic (7.83e-3)" "unprognostic (3.26e-1)" "unprognostic (6.94e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-2)" "prognostic favorable (7.04e-4)" "unprognostic (4.54e-2)" "unprognostic (6.08e-2)" "unprognostic (5.29e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (6.50e-6)" "unprognostic (1.46e-3)" "unprognostic (9.63e-2)" "unprognostic (3.31e-1)" "unprognostic (4.00e-3)" LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Host-virus interaction" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 320.3;Leydig cells: 234.3;Peritubular cells: 183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" LRP2BP DKFZp761O0113 ENSG00000109771 "LRP2 binding protein" Q9P2M1 4 185363872-185395924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Astrocytes: 55.7;Early spermatids: 54.0;Inhibitory neurons: 33.4;Late spermatids: 51.1;Oligodendrocyte precursor cells: 38.5;Oligodendrocytes: 32.9;Rod photoreceptor cells: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036664, HPA036665" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA036664: AB_10672361, HPA036665: AB_10673660" "unprognostic (2.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-3)" "unprognostic (3.15e-5)" "unprognostic (2.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (9.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.84e-2)" "unprognostic (4.35e-4)" "unprognostic (2.17e-2)" "unprognostic (9.76e-3)" "unprognostic (2.15e-1)" "unprognostic (5.26e-3)" "unprognostic (1.29e-1)" "unprognostic (4.54e-4)" LRP3 "hLRp105, LRP-3" ENSG00000130881 "LDL receptor related protein 3" O75074 19 33177603-33208864 "Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Bipolar cells: 12.1;Excitatory neurons: 19.2;Horizontal cells: 24.4;Inhibitory neurons: 19.0;Oligodendrocyte precursor cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041658 Approved "Lipid droplets" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Lipid droplets" "HPA041658: " "unprognostic (3.10e-1)" "unprognostic (2.55e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (1.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.07e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.12e-7)" "unprognostic (1.34e-1)" "unprognostic (2.71e-3)" "unprognostic (4.36e-1)" "unprognostic (2.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.32e-1)" LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 79.0;Endothelial cells: 138.4;Extravillous trophoblasts: 195.3;Smooth muscle cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Cancer enhanced" "Detected in many" "lymphoma: 9.7;Sarcoma: 9.5;testis cancer: 7.6" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" LRRC39 "MGC14816, myomasp" ENSG00000122477 "Leucine rich repeat containing 39" Q96DD0 1 100148448-100178273 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 107.0;retina: 117.9;skeletal muscle: 431.0;tongue: 172.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 178.5;Cone photoreceptor cells: 58.6;Early spermatids: 263.1;Hofbauer cells: 65.6;Inhibitory neurons: 60.9;Rod photoreceptor cells: 66.9;Skeletal myocytes: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077159 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 52: Spermatids - Smell perception" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA077159: AB_2732333" "unprognostic (7.68e-2)" "unprognostic (3.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-1)" "unprognostic (6.40e-2)" "unprognostic (1.27e-1)" "unprognostic (4.07e-3)" "unprognostic (1.58e-2)" "unprognostic (1.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (3.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (8.17e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-4)" LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 3.6;Endothelial cells: 2.6;granulocytes: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 105.0;Cardiomyocytes: 89.9;Fibroblasts: 92.5;Leydig cells: 95.6;Mucus glandular cells: 116.8;Peritubular cells: 162.3;Smooth muscle cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 67.4;Fibroblasts: 84.9;Peritubular cells: 81.6;Salivary duct cells: 57.4;Smooth muscle cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Kidney - Fibroblasts" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 46: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.6;Leydig cells: 975.0;Peritubular cells: 618.8;Schwann cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 233.3;Spermatocytes: 449.6" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cancer enhanced" "Detected in many" "cervical cancer: 140.9" "Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 10 "B-cells: 154.3;Hofbauer cells: 258.4;Kupffer cells: 157.5;Langerhans cells: 123.9;Macrophages: 146.7;Microglial cells: 103.1;monocytes: 146.5;Schwann cells: 66.4" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Group enriched" "Detected in some" 176 "Leukemia: 38.8;lymphoma: 38.4;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Group enriched" "Detected in many" 4 "Early spermatids: 42.3;Late spermatids: 99.0;Syncytiotrophoblasts: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.8" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3373.9;Hofbauer cells: 2648.2;Kupffer cells: 5103.6;Langerhans cells: 5870.5;Macrophages: 4276.5;monocytes: 3002.5;Serous glandular cells: 2631.0" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 1889.9;Leukemia: 787.2" "Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;monocytes: 5.4" "Cancer enhanced" "Detected in all" "Bone cancer: 113.8" "Kidney - Fibroblasts, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: Bone cancer - Transcription" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA035865: AB_10672099, HPA041189: AB_2677357" "unprognostic (1.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.46e-2)" "unprognostic (1.46e-2)" "unprognostic (7.71e-3)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.17e-2)" "unprognostic (7.32e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (3.27e-2)" "unprognostic (4.58e-2)" "unprognostic (8.78e-2)" "unprognostic (4.66e-2)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 404.8;Kupffer cells: 407.4;Macrophages: 500.9;monocytes: 673.1;Squamous epithelial cells: 374.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cancer enhanced" "Detected in many" "Bone cancer: 31.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" MAFK "NFE2U, P18" ENSG00000198517 "MAF bZIP transcription factor K" O60675 7 1530702-1543043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 85.3;Syncytiotrophoblasts: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026820, HPA060841" Enhanced Enhanced Nucleoplasm No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB026820: , HPA060841: AB_2684377" "unprognostic (6.82e-2)" "unprognostic (3.71e-3)" "unprognostic (1.49e-2)" "unprognostic (2.55e-1)" "unprognostic (6.44e-3)" "unprognostic (1.19e-1)" "unprognostic (9.44e-2)" "unprognostic (2.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-2)" "unprognostic (2.81e-1)" "unprognostic (1.40e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (5.59e-2)" "unprognostic (2.14e-1)" MAG "GMA, S-MAG, SIGLEC-4A, SIGLEC4A" ENSG00000105695 "Myelin associated glycoprotein" P20916 19 35292125-35313807 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 731.4" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 252.8" "Cancer enriched" "Detected in some" 7 "glioma: 20.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enriched" "Detected in some" 7 "skin cancer: 7.9" "Kidney - Intercalated cells" "Region enhanced" "Detected in all" "white matter: 2742.2" "Low region specificity" "Detected in all" "CAB009345, HPA012499" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "CAB009345: AB_670104, HPA012499: AB_1854238" "unprognostic (2.70e-3)" "unprognostic (2.70e-2)" "unprognostic (8.06e-3)" "unprognostic (1.23e-1)" "unprognostic (6.93e-2)" "unprognostic (3.74e-1)" "unprognostic (1.50e-1)" "unprognostic (2.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (5.62e-2)" "unprognostic (5.18e-4)" "unprognostic (6.29e-2)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" "unprognostic (1.66e-1)" MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 515.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 57.3" "Breast - Fibroblasts, Kidney - Fibroblasts, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoli, Nucleoli rim" "HPA011324: AB_1853499, HPA011971: " "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.95e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-2)" "unprognostic (9.93e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "prognostic favorable (2.60e-4)" "unprognostic (6.37e-2)" "unprognostic (1.81e-2)" "unprognostic (1.29e-3)" "unprognostic (1.90e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.5" "Cell type enriched" "Detected in some" 7 "Spermatocytes: 181.6" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0" "Region enriched" "Detected in single" 4 "cerebellum: 2.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Cancer enriched" "Detected in some" 9 "Gallbladder cancer: 12.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.37e-1)" "unprognostic (6.43e-3)" "unprognostic (3.69e-2)" "unprognostic (7.05e-2)" "unprognostic (9.64e-3)" "unprognostic (2.92e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" "unprognostic (9.11e-2)" "unprognostic (4.11e-2)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-2)" MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 187.3;Alveolar cells type 2: 230.3;Distal enterocytes: 557.1;Ductal cells: 264.8;Paneth cells: 210.1;Proximal enterocytes: 780.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" MAP1LC3B ATG8F ENSG00000140941 "Microtubule associated protein 1 light chain 3 beta" Q9GZQ8 16 87383953-87404779 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 725.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB037216, HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 14: Endometrium - Transcription regulation" Vesicles Nucleoplasm "CAB037216: AB_796155, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (4.70e-3)" "unprognostic (2.89e-1)" "unprognostic (3.21e-1)" "unprognostic (9.70e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-2)" "unprognostic (4.98e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "prognostic favorable (2.77e-7)" "prognostic unfavorable (8.97e-4)" "unprognostic (9.66e-2)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 10.8;choroid plexus: 13.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Granulosa cells: 7.5;Theca cells: 19.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.7" "Kidney - Ascending Loop of Henle cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 43.5;dendritic cells: 52.8;Langerhans cells: 30.6;monocytes: 22.5;Plasma cells: 34.7;Rod photoreceptor cells: 65.2;T-cells: 39.5" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 39 "Leukemia: 16.9;lymphoma: 52.8;Myeloma: 29.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 386.6;Microglial cells: 328.4;Oligodendrocytes: 1071.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 353.3" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 29.9" "Kidney - Podocytes, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.0;Oligodendrocytes: 411.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced NA NA 13000000 "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA016738: AB_1853571, HPA016739: AB_1853570" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (2.55e-2)" "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (8.53e-2)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.93e-2)" "unprognostic (5.40e-2)" "unprognostic (2.22e-3)" "unprognostic (5.83e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (3.99e-3)" MARVELD1 "bA548K23.8, FLJ22343, FLJ23440, GB14, MGC4415, MRVLDC1" ENSG00000155254 "MARVEL domain containing 1" Q9BSK0 10 97713173-97718150 "Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 83.7;Schwann cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.2;intermediate monocyte: 2.7;myeloid DC: 3.1" "Group enriched" "Detected in many" 18 "dendritic cells: 3.1;monocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" "unprognostic (3.28e-2)" "unprognostic (2.11e-2)" "unprognostic (1.26e-3)" "unprognostic (3.05e-2)" "unprognostic (1.36e-3)" "unprognostic (8.82e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (5.85e-5)" "unprognostic (1.54e-2)" "unprognostic (7.44e-3)" "unprognostic (3.40e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (8.89e-7)" "unprognostic (3.92e-3)" "unprognostic (7.02e-2)" "unprognostic (1.50e-1)" "unprognostic (3.86e-3)" MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 127.9;Bipolar cells: 62.9;Cone photoreceptor cells: 98.2;Endothelial cells: 66.6;Intestinal goblet cells: 66.0;Microglial cells: 90.3;Oligodendrocytes: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 33.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Group enriched" "Detected in all" 4 "Cardiomyocytes: 3168.9;Proximal tubular cells: 1478.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Macrophages, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 77: Cardiomyocytes - Muscle contraction" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 437.7;Excitatory neurons: 725.5;Inhibitory neurons: 743.2;Microglial cells: 711.5;Skeletal myocytes: 625.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Group enriched" "Detected in all" 5 "Leukemia: 98.5;lymphoma: 66.9;Myeloma: 168.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 102.8" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Disease related genes, Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 108.6;Oligodendrocytes: 214.7;Rod photoreceptor cells: 136.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 39.6" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "CAB011521: AB_776272, HPA056000: AB_2683004, HPA058641: AB_2683784" "unprognostic (6.84e-2)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-1)" "prognostic favorable (2.70e-5)" "unprognostic (2.45e-2)" "unprognostic (7.78e-3)" "unprognostic (2.36e-2)" "unprognostic (5.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (6.52e-2)" "unprognostic (9.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-2)" METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase like 1" Q9UBP6 12 57768471-57772119 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 16: Non-specific - RNA binding" Nucleoplasm "HPA020914: AB_1853830, HPA050450: AB_2681130" "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 238.8;Fibroblasts: 59.2;Granulosa cells: 89.6;Leydig cells: 55.4;Peritubular cells: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 109.0;Distal enterocytes: 44.0;Excitatory neurons: 47.5;Gastric mucus-secreting cells: 32.2;Glandular and luminal cells: 40.8;Intestinal goblet cells: 39.4;Ionocytes: 35.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 5.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Ascending Loop of Henle cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 125.3;Basal squamous epithelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 646.2;Intestinal goblet cells: 236.6;Paneth cells: 471.1;Proximal enterocytes: 1075.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 12 "Plasma cells: 22.7" "Cancer enriched" "Detected in some" 9 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 35: Liver cancer - Metabolism" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "HPA005662: AB_2667382" "unprognostic (4.09e-2)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (7.40e-3)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.71e-13)" "unprognostic (1.54e-1)" "unprognostic (1.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.47e-2)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 77.6;Cytotrophoblasts: 79.6;Endometrial stromal cells: 274.1;Prostatic glandular cells: 121.5;Proximal enterocytes: 327.5;Syncytiotrophoblasts: 128.8" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Fibroblasts, Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Adipocytes: 220.5;Endothelial cells: 134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 549.0;Hepatocytes: 617.4;Paneth cells: 523.7;Proximal enterocytes: 1336.8;Proximal tubular cells: 464.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 50: Enterocytes - Absorption" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 294.4;Basal respiratory cells: 269.4;Glandular and luminal cells: 182.6;Squamous epithelial cells: 371.0;Suprabasal keratinocytes: 444.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 59.8;Fibroblasts: 123.2;Late spermatids: 91.7;Leydig cells: 73.3;Peritubular cells: 96.6;Theca cells: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 100.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 44.7;kidney: 24.1;testis: 28.9" "Cell type enhanced" "Detected in some" "Astrocytes: 29.1;Granulosa cells: 14.7;Proximal enterocytes: 22.5;Sertoli cells: 35.9" "Cancer enriched" "Detected in some" 7 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 2.0" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" "HPA022011: AB_2670880" "unprognostic (9.21e-5)" "unprognostic (5.22e-2)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (5.11e-2)" "unprognostic (3.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.71e-1)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (6.06e-4)" MS4A2 "APY, FCER1B, IGER, MS4A1" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.6" "Cell type enriched" "Detected in some" 23 "granulocytes: 963.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 908 "basophil: 275.5" "Lineage enriched" "Detected in single" 1467 "granulocytes: 275.5" "Cancer enriched" "Detected in single" 10 "Leukemia: 1.8" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Kidney - T-cells, Lung - Mast cells, Skin - Mast cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 15.3" HPA059967 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 46: Granulocytes - Mast cell degranulation" "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 234.7;Peritubular cells: 118.5;Smooth muscle cells: 148.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cancer enhanced" "Detected in all" "Rhabdoid: 93.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 198.3;Proximal enterocytes: 54.8;Proximal tubular cells: 42.9;Thymic epithelial cells: 45.4" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" MSX1 "HOX7, HYD1, OFC5" ENSG00000163132 "Msh homeobox 1" P28360 4 4859665-4863936 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.0;choroid plexus: 98.0" "Cell type enhanced" "Detected in many" "Adipocytes: 116.5;Endometrial ciliated cells: 349.0;Glandular and luminal cells: 481.2" "Cancer enriched" "Detected in all" 17 "endometrial cancer: 246.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.9" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB026198, HPA063895, HPA073604" Enhanced Supported Nucleoplasm NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB026198: , HPA063895: AB_2685145, HPA073604: AB_2686617" "unprognostic (1.12e-1)" "unprognostic (1.93e-2)" "unprognostic (3.39e-2)" "prognostic favorable (1.64e-7)" "unprognostic (9.13e-2)" "unprognostic (1.16e-3)" "unprognostic (4.07e-3)" "unprognostic (3.81e-2)" "unprognostic (1.48e-2)" "unprognostic (2.21e-3)" "unprognostic (4.78e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (4.35e-2)" "unprognostic (2.06e-1)" "unprognostic (2.34e-3)" "unprognostic (1.33e-2)" MT1G "MT1, MT1K" ENSG00000125144 "Metallothionein 1G" P13640 16 56666730-56668065 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 3543.0;liver: 6959.4;thyroid gland: 2886.6" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 91030.0" "Group enriched" "Detected in all" 4 "liver cancer: 320.1;ovarian cancer: 106.9;prostate cancer: 103.9;testis cancer: 269.9;thyroid cancer: 369.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 158.0;colorectal cancer: 123.9;Leukemia: 130.6" "Kidney - Proximal tubular cells, Stomach - Chief cells" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.62e-1)" "unprognostic (4.21e-1)" "unprognostic (2.77e-2)" "unprognostic (3.15e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (5.97e-2)" "unprognostic (2.49e-2)" "unprognostic (4.21e-1)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (7.92e-2)" "unprognostic (2.26e-2)" MT1H MT1 ENSG00000205358 "Metallothionein 1H" P80294 16 56669814-56671129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 845.2;liver: 1137.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 22589.8" "Cancer enhanced" "Detected in many" "testis cancer: 173.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 17.3;Myeloma: 12.2" "Kidney - Proximal tubular cells, Stomach - Chief cells" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-1)" "unprognostic (8.65e-2)" "prognostic unfavorable (2.37e-7)" "unprognostic (8.48e-3)" "unprognostic (6.26e-2)" "unprognostic (7.44e-2)" "unprognostic (3.31e-1)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (5.77e-2)" "unprognostic (3.50e-2)" "unprognostic (2.37e-2)" "unprognostic (1.34e-1)" MT1X "MT-1l, MT1" ENSG00000187193 "Metallothionein 1X" P80297 16 56682470-56684196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 4031.0;skeletal muscle: 6099.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 9983.4;Proximal enterocytes: 3651.1;Proximal tubular cells: 13199.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (8.15e-2)" "unprognostic (9.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.18e-3)" "unprognostic (7.05e-3)" "unprognostic (7.26e-3)" "unprognostic (9.49e-3)" "unprognostic (9.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.40e-2)" "unprognostic (4.85e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-10)" "unprognostic (1.56e-1)" "unprognostic (4.25e-2)" "unprognostic (4.11e-1)" "unprognostic (1.37e-3)" MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 559.0;Proximal tubular cells: 458.0;Spermatocytes: 402.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" MTFR1 "CHPPR, FAM54A2, KIAA0009" ENSG00000066855 "Mitochondrial fission regulator 1" Q15390 8 65644734-65771261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 234.9;Late spermatids: 862.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023152, HPA056120" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Spermatids - Spermatogenesis" Mitochondria Cytosol "HPA023152: AB_1854176, HPA056120: AB_2683043" "prognostic unfavorable (4.06e-4)" "unprognostic (4.58e-2)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (6.56e-3)" "unprognostic (3.93e-2)" "unprognostic (1.66e-1)" "unprognostic (3.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.53e-1)" "unprognostic (5.69e-3)" "unprognostic (5.44e-2)" "unprognostic (6.63e-3)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (8.25e-2)" MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 225.7;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 46: Non-specific - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 203.2;monocytes: 241.5;Oligodendrocyte precursor cells: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 12: Non-specific - Chromatin organization" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 437.7;Endometrial ciliated cells: 117.6;Enteroendocrine cells: 163.6;Intestinal goblet cells: 440.6;Paneth cells: 328.1;Proximal enterocytes: 406.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 166.1;Gastric cancer: 61.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1949.7" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 965.0" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enriched" "Detected in single" 7 "basal ganglia: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 12.0" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in many" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Myeloma - Humoral immune response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 150.8;Extravillous trophoblasts: 294.8;Fibroblasts: 183.8;Leydig cells: 169.3;Peritubular cells: 176.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.1;testis: 11.8" "Cell type enhanced" "Detected in many" "NK-cells: 185.7;Spermatocytes: 33.2;T-cells: 78.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA008791: AB_1078540" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.57e-1)" "unprognostic (7.23e-4)" "unprognostic (2.26e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.78e-2)" "unprognostic (1.13e-2)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.03e-8)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.87e-2)" MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.1;Excitatory neurons: 218.1;Inhibitory neurons: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 165.0" "Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 49: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "B-cells: 58.8;Kupffer cells: 72.8;Langerhans cells: 76.6;Macrophages: 64.6;monocytes: 252.2;NK-cells: 164.4;T-cells: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 84.6;lymphoma: 99.5" "Adipose subcutaneous - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.1;kidney: 5.3;parathyroid gland: 8.8;retina: 5.8" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 50.0;Early spermatids: 32.9;Inhibitory neurons: 17.9;Late spermatids: 27.4;Rod photoreceptor cells: 55.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.6" "Kidney - Ascending Loop of Henle cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Not detected" "Not detected" HPA045483 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 44: Photoreceptor cells - Visual perception" "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" MYO7A "DFNA11, DFNB2, NSRD2, USH1B" ENSG00000137474 "Myosin VIIA" Q13402 11 77128246-77215241 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Leber congenital amaurosis, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 41.9;choroid plexus: 53.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.6;Cone photoreceptor cells: 22.4;Cytotrophoblasts: 43.7;Hofbauer cells: 25.9;Muller glia cells: 15.6;Rod photoreceptor cells: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.6;intermediate monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.6" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB034059 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 28: Cytotrophoblasts - Unknown function" "CAB034059: AB_2148626" "unprognostic (1.14e-3)" "unprognostic (2.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (4.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (3.03e-2)" MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 8 "Plasma cells: 4370.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Cancer enriched" "Detected in some" 5 "Myeloma: 791.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.9;Inhibitory neurons: 158.2;Oligodendrocyte precursor cells: 683.5;Oligodendrocytes: 212.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 514.3;Excitatory neurons: 454.5;Inhibitory neurons: 430.4;Oligodendrocyte precursor cells: 899.2;Oligodendrocytes: 956.8;Schwann cells: 253.4" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 117.9" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" NCF1 "NCF1A, NOXO2, p47phox, SH3PXD1A" ENSG00000158517 "Neutrophil cytosolic factor 1" P14598 7 74773962-74789376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.4;lymphoid tissue: 97.5" "Cell type enhanced" "Detected in some" "B-cells: 61.1;dendritic cells: 17.8;Macrophages: 28.0;Plasma cells: 85.1;T-cells: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1165.0;classical monocyte: 673.5;eosinophil: 1467.3;neutrophil: 2128.0" "Group enriched" "Detected in all" 5 "granulocytes: 2128.0;monocytes: 673.5" "Cancer enhanced" "Detected in some" "Leukemia: 30.5;lymphoma: 81.5" "Kidney - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004524, HPA047836, HPA052095" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" "CAB004524: AB_627987, HPA047836: AB_2680173, HPA052095: AB_2681721" "unprognostic (4.93e-2)" "unprognostic (8.34e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (3.55e-3)" "unprognostic (7.60e-2)" "unprognostic (4.75e-2)" "unprognostic (6.23e-3)" "unprognostic (9.99e-2)" "unprognostic (6.61e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-3)" "unprognostic (3.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-1)" NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 720.8;Mucus glandular cells: 704.5;Salivary duct cells: 557.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: AB_10670031, HPA030290: AB_10601971, HPA030291: AB_10669597, HPA030292: AB_10670834" "unprognostic (1.01e-2)" "unprognostic (3.21e-2)" "unprognostic (7.32e-3)" "unprognostic (7.27e-3)" "unprognostic (1.54e-1)" "unprognostic (4.67e-2)" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (2.73e-1)" "unprognostic (2.14e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-2)" "prognostic favorable (1.78e-6)" "unprognostic (2.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 244.9;Peritubular cells: 206.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cancer enhanced" "Detected in many" "testis cancer: 57.4" "Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Melanocytes: 438.9;Muller glia cells: 492.5;Schwann cells: 416.7;Serous glandular cells: 858.8" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;liver: 1.3;lymphoid tissue: 2.9;retina: 2.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 296.0;Inhibitory neurons: 126.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056189 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA056189: AB_2683061" "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.1;Inhibitory neurons: 172.1;Oligodendrocyte precursor cells: 76.1;Theca cells: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" "HPA013180: AB_1854383" "unprognostic (2.67e-2)" "unprognostic (3.46e-2)" "unprognostic (3.90e-1)" "unprognostic (1.51e-3)" "unprognostic (2.25e-1)" "unprognostic (5.26e-3)" "unprognostic (1.10e-2)" "unprognostic (5.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (5.53e-6)" "unprognostic (3.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.79e-2)" "unprognostic (1.32e-1)" NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 71.7;Hepatocytes: 119.6;Intestinal goblet cells: 37.5;Oligodendrocyte precursor cells: 48.1;Paneth cells: 49.5;Proximal enterocytes: 69.7" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.4;liver cancer: 8.7" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.3" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 179.9;Skeletal myocytes: 206.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Skeletal myocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA007533: AB_2667855" "unprognostic (3.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.84e-1)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (8.12e-2)" "prognostic favorable (4.66e-4)" "prognostic favorable (2.35e-4)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.92e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-2)" NFYB "CBF-A, HAP3, NF-YB" ENSG00000120837 "Nuclear transcription factor Y subunit beta" P25208 12 104117086-104138241 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 143.8;Syncytiotrophoblasts: 375.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004211, HPA065646" Supported Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "CAB004211: AB_628018, HPA065646: " "unprognostic (5.82e-2)" "unprognostic (2.44e-3)" "unprognostic (4.90e-2)" "unprognostic (7.10e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "unprognostic (2.10e-2)" "unprognostic (2.44e-1)" "unprognostic (7.36e-2)" "unprognostic (2.63e-1)" "unprognostic (9.39e-2)" "unprognostic (8.51e-2)" "prognostic unfavorable (9.28e-5)" "unprognostic (1.62e-3)" "unprognostic (4.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.81e-3)" NHLRC4 ENSG00000257108 "NHL repeat containing 4" P0CG21 16 567005-569495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.7;kidney: 10.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 19.7;Endometrial ciliated cells: 23.8;Erythroid cells: 10.5;Leydig cells: 8.6;Respiratory ciliated cells: 26.5;Theca cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 2.9" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" HPA077301 Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 56: Ciliated cells - Cilium assembly" Mitochondria "HPA077301: " "unprognostic (7.95e-2)" "unprognostic (5.87e-2)" "unprognostic (4.28e-3)" "unprognostic (2.53e-2)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-3)" "unprognostic (1.19e-2)" "unprognostic (1.16e-2)" "unprognostic (5.16e-3)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.60e-1)" NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 117.6;Proximal tubular cells: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 16: Non-specific - RNA binding" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" NIT2 ENSG00000114021 "Nitrilase family member 2" Q9NQR4 3 100334739-100361635 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.9;Proximal tubular cells: 678.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036999, HPA041289" Approved Supported Centrosome,Cytosol NA NA 1700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Centrosome "HPA036999: AB_10672105, HPA041289: " "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.06e-3)" "prognostic unfavorable (4.62e-4)" "unprognostic (6.28e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-1)" "unprognostic (1.12e-1)" "unprognostic (6.60e-3)" "unprognostic (2.21e-1)" "unprognostic (6.68e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (8.26e-2)" "unprognostic (1.47e-3)" NLRP6 "CLR11.4, NALP6, PAN3, PYPAF5" ENSG00000174885 "NLR family pyrin domain containing 6" P59044 11 278407-285388 "Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 39.9" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 9.8;T-cells: 3.7" "Group enriched" "Detected in some" 4 "colorectal cancer: 0.9;liver cancer: 1.2;renal cancer: 1.5;stomach cancer: 1.8" "Region enhanced" "Detected in single" "cerebral cortex: 3.6" "Group enriched" "Detected in many" 4 "neutrophil: 15.4;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.4;monocytes: 4.6" "Cancer enhanced" "Detected in some" "Leukemia: 1.1;lymphoma: 1.3;Myeloma: 2.0" "Adipose visceral - Neutrophils, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043681, HPA048500" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA043681: AB_2678614, HPA048500: AB_2680422" "unprognostic (6.37e-3)" "unprognostic (4.69e-2)" "unprognostic (4.26e-2)" "unprognostic (3.42e-2)" "unprognostic (6.40e-2)" "unprognostic (1.18e-2)" "prognostic favorable (4.23e-5)" "unprognostic (8.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (2.19e-1)" "unprognostic (3.11e-3)" "unprognostic (4.96e-2)" "unprognostic (2.14e-2)" "unprognostic (6.90e-3)" "unprognostic (3.69e-2)" NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015781-139045939 "Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.1;monocytes: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 75: Myeloid cells - Innate immune response" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: AB_2668640, HPA053714: AB_2682238" "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavorable (6.23e-4)" NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.5;Microglial cells: 25.5;Schwann cells: 16.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 63: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 54.6;Astrocytes: 65.2;Endothelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913975 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.9;liver: 142.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 84.7;Exocrine glandular cells: 34.0;Gastric mucus-secreting cells: 100.2;Hepatocytes: 210.5;Proximal enterocytes: 40.2" "Cancer enriched" "Detected in many" 5 "liver cancer: 52.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 13.3;liver cancer: 16.6" "Kidney - Intercalated cells, Lung - Alveolar cells type 2" "Region enriched" "Detected in single" 6 "cerebellum: 1.7" "Not detected" "Not detected" HPA003983 Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 29: Hepatocytes - Metabolism" Nucleoplasm Vesicles "HPA003983: " "unprognostic (2.99e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-3)" "unprognostic (9.21e-2)" "unprognostic (8.22e-2)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (2.11e-2)" "unprognostic (6.74e-3)" "unprognostic (1.04e-1)" "unprognostic (2.03e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 540.8;Leydig cells: 512.2;Peritubular cells: 619.7;Smooth muscle cells: 474.2;Theca cells: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 264.9" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 17: Granulosa cells - Transcription regulation" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" NRIP3 C11orf14 ENSG00000175352 "Nuclear receptor interacting protein 3" Q9NQ35 11 8980576-9004049 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.9;retina: 24.5;testis: 43.5" "Cell type enhanced" "Detected in many" "Early spermatids: 507.6;Horizontal cells: 128.2;Inhibitory neurons: 93.8;Late spermatids: 530.7;Spermatocytes: 174.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 13.1" "Lineage enriched" "Detected in many" 12 "granulocytes: 13.1" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058827, HPA072961" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 32: Neurons - Synaptic function" Cytosol "HPA058827: AB_2683829, HPA072961: " "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.84e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (2.03e-4)" "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (3.63e-2)" "unprognostic (1.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" "unprognostic (5.88e-3)" "unprognostic (1.30e-1)" NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Group enriched" "Detected in many" 5 "Adipocytes: 273.8;Endothelial cells: 119.1;Excitatory neurons: 71.0;Extravillous trophoblasts: 78.5;Schwann cells: 142.1" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cancer enhanced" "Detected in many" "Bone cancer: 96.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 192.6;Cytotrophoblasts: 120.3;Granulosa cells: 124.0;Melanocytes: 426.7;Suprabasal keratinocytes: 146.3;Theca cells: 129.9" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.4;skin cancer: 66.8" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No 21000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 63: Non-specific - Unknown function" "Cluster 43: Non-specific - Cell proliferation" Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" NUTM2F "DKFZp434I1117, FAM22F" ENSG00000130950 "NUT family member 2F" A1L443 9 94318196-94328644 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.9" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Excitatory neurons: 42.3;Inhibitory neurons: 28.3;Microglial cells: 10.9;Oligodendrocyte precursor cells: 26.0;Oligodendrocytes: 29.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Testis - Late spermatids" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 6: BEWO - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Nuclear bodies" "HPA064635: " "unprognostic (1.40e-1)" "unprognostic (4.93e-3)" "unprognostic (4.16e-2)" "unprognostic (1.47e-1)" "unprognostic (9.26e-3)" "unprognostic (1.03e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (6.72e-3)" "unprognostic (8.48e-2)" "unprognostic (1.11e-2)" "unprognostic (5.14e-1)" "unprognostic (1.83e-2)" NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 24.1;Endometrial ciliated cells: 39.8;Glandular and luminal cells: 14.1;Granulosa cells: 14.2;Late spermatids: 10.1;Proximal tubular cells: 17.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 7.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" Cytosol "HPA045526: AB_10961044" "prognostic favorable (6.53e-4)" "unprognostic (9.70e-2)" "unprognostic (4.78e-3)" "prognostic favorable (3.83e-8)" "unprognostic (2.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-4)" "unprognostic (1.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-3)" "unprognostic (5.58e-2)" "prognostic favorable (9.60e-4)" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-2)" NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 151.5" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.5;Rhabdoid: 6.3" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 925.4;Pancreatic endocrine cells: 647.5;Proximal enterocytes: 719.1;Proximal tubular cells: 1238.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" ODF2L KIAA1229 ENSG00000122417 "Outer dense fiber of sperm tails 2 like" Q9ULJ1 1 86346824-86396342 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 338.9;Respiratory ciliated cells: 255.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028020, HPA028095, HPA028333" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 38: Non-specific - mRNA processing" "Cluster 1: T-cells - Immune response" "HPA028020: AB_10601670, HPA028095: AB_10611385, HPA028333: AB_10601007" "unprognostic (4.81e-2)" "unprognostic (3.11e-1)" "unprognostic (1.03e-1)" "unprognostic (4.72e-2)" "unprognostic (2.92e-2)" "unprognostic (3.80e-3)" "unprognostic (5.61e-3)" "unprognostic (2.25e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-1)" "unprognostic (6.27e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (4.69e-7)" "unprognostic (2.40e-1)" "unprognostic (5.86e-2)" "unprognostic (2.40e-1)" "unprognostic (5.04e-3)" OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 555.7;choroid plexus: 246.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 94.8;Endothelial cells: 97.9;Excitatory neurons: 190.6;Inhibitory neurons: 68.3;Schwann cells: 74.5" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cancer enhanced" "Detected in many" "Bone cancer: 119.8;Neuroblastoma: 76.6" "Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" NA NA 200000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA057444: AB_2683443" "unprognostic (6.77e-2)" "prognostic favorable (7.14e-4)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.04e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (9.46e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" "unprognostic (7.53e-4)" OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 20 "Cone photoreceptor cells: 86.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Cytosol" "Cytokinetic bridge" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Group enriched" "Detected in some" 6 "Hofbauer cells: 50.1;Kupffer cells: 31.8;Langerhans cells: 16.1;Macrophages: 43.9;monocytes: 41.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cancer enhanced" "Detected in some" "Leukemia: 7.8;thyroid cancer: 5.9" "Adipose subcutaneous - Macrophages, Kidney - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 50.6;Oligodendrocyte precursor cells: 40.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.4" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762481-42764261 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 56.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 6.5;Melanocytes: 5.2;Paneth cells: 5.3;Proximal enterocytes: 14.1" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 67.0;eosinophil: 144.5" "Lineage enriched" "Detected in many" 79 "granulocytes: 144.5" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" HPA051433 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cancer enhanced" "Detected in some" "Rhabdoid: 8.7" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4" "Cell type enhanced" "Detected in some" "B-cells: 111.8;Langerhans cells: 74.1;NK-cells: 27.5;Plasma cells: 36.2;Schwann cells: 38.3;T-cells: 85.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 256.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Leukemia: 4.5;lymphoma: 14.3;Myeloma: 17.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036757, HPA065766" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 24.2;Kupffer cells: 38.1;Macrophages: 63.2;Microglial cells: 64.8;monocytes: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Kidney - Macrophages, Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "B-cells: 42.1;Kupffer cells: 15.6;NK-cells: 72.2;Plasma cells: 37.5;T-cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 32 "Leukemia: 62.4;lymphoma: 76.5;Myeloma: 48.9" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - T-cells" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 45.0;Cone photoreceptor cells: 167.2;Leydig cells: 50.6;Peritubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" P4HA2 C-P4Halpha(II) ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 129.7;Basal respiratory cells: 105.0;Endometrial stromal cells: 104.1;Pancreatic endocrine cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 13000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" PACC1 "C1orf75, FLJ10874, PAC, TMEM206" ENSG00000065600 "Proton activated chloride channel 1" Q9H813 1 212363928-212414901 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.1" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 32.3;Oligodendrocytes: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008540 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 18: Non-specific - RNA binding" "Cluster 68: Muller glia cells - Visual perception" "HPA008540: AB_10794083" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (9.23e-2)" "unprognostic (1.02e-1)" "unprognostic (2.74e-2)" "unprognostic (3.09e-2)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.06e-3)" "unprognostic (6.33e-2)" "unprognostic (1.02e-1)" "unprognostic (9.10e-2)" "unprognostic (6.98e-2)" PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 149.3;retina: 64.3" "Group enriched" "Detected in some" 8 "Bipolar cells: 65.1;Cone photoreceptor cells: 105.1;dendritic cells: 64.9;Excitatory neurons: 49.2;Horizontal cells: 88.4;Inhibitory neurons: 46.6;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cancer enhanced" "Detected in many" "Myeloma: 20.7;prostate cancer: 9.6" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 44: Photoreceptor cells - Visual perception" Vesicles Nucleoplasm "CAB009929: AB_2268057, HPA028852: AB_10602812, HPA055491: AB_2682834" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.72e-2)" "unprognostic (2.47e-3)" "unprognostic (2.14e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (6.63e-2)" "unprognostic (3.95e-4)" "unprognostic (9.12e-2)" "unprognostic (3.02e-2)" "unprognostic (4.18e-2)" "unprognostic (9.90e-2)" "unprognostic (5.50e-2)" "unprognostic (9.33e-2)" PAGR1 "C16orf53, GAS, MGC4606, PA1" ENSG00000280789 "PAXIP1 associated glutamate rich protein 1" Q9BTK6 16 29816152-29822489 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 166.5" "Cell type enhanced" "Detected in many" "Astrocytes: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "HPA041440, HPA043608" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 8: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "HPA041440: AB_10795541, HPA043608: AB_10797144" "unprognostic (2.35e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" "unprognostic (1.44e-2)" "unprognostic (4.20e-1)" "unprognostic (1.14e-3)" "unprognostic (7.09e-3)" "unprognostic (5.12e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (1.84e-3)" "unprognostic (3.41e-2)" "unprognostic (1.51e-2)" "unprognostic (8.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (5.39e-2)" PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 742.2;Peritubular cells: 400.9;Smooth muscle cells: 300.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" PANK1 "MGC24596, PANK, PANK1a, PANK1b" ENSG00000152782 "Pantothenate kinase 1" Q8TE04 10 89579497-89645572 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 45.2;liver: 109.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 41.5;Hepatocytes: 143.6;Proximal tubular cells: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (6.71e-2)" "unprognostic (6.97e-2)" "prognostic favorable (1.50e-4)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.55e-4)" "unprognostic (4.61e-2)" "prognostic favorable (1.55e-10)" "unprognostic (3.49e-2)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" "unprognostic (6.64e-2)" PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.6;Oligodendrocyte precursor cells: 24.5;Squamous epithelial cells: 25.6;Suprabasal keratinocytes: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 27: TE 441.T - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" PARP14 "ARTD8, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 197.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "B-cells: 86.0;granulocytes: 13.0;NK-cells: 41.7;T-cells: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 18.2;lymphoma: 18.0" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.8;Cardiomyocytes: 22.4;NK-cells: 39.6;T-cells: 27.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cancer enhanced" "Detected in some" "lymphoma: 6.4;Myeloma: 12.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 429.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 713.1;Proximal tubular cells: 698.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: AB_2684594" "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 5 "Adipocytes: 34.8;Endothelial cells: 34.3;Hofbauer cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.8;Endometrial stromal cells: 8.3;Fibroblasts: 9.3;Horizontal cells: 6.4;Peritubular cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear membrane" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Early spermatids: 40.8;Late spermatids: 29.5;Spermatocytes: 20.8" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 7 "Late spermatids: 4124.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 35: Bipolar cells - Visual perception" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 189.1;Oligodendrocytes: 530.4" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.9;Fibroblasts: 7.3;granulocytes: 12.6;Langerhans cells: 14.1;Leydig cells: 6.9;Microglial cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Cell type enhanced" "Detected in many" "Adipocytes: 114.4;Endothelial cells: 72.1;Excitatory neurons: 69.1;Inhibitory neurons: 34.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cancer enriched" "Detected in many" 4 "cervical cancer: 104.1" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 56: Neurons - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 95.2;Bipolar cells: 80.4;Cardiomyocytes: 212.4;Horizontal cells: 97.4;Inhibitory neurons: 76.7;Smooth muscle cells: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 15.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 65.2;Inhibitory neurons: 56.9;Oligodendrocyte precursor cells: 54.4;Peritubular cells: 98.2;Smooth muscle cells: 74.7" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Peritubular cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 9.6;Gastric mucus-secreting cells: 8.3;Plasma cells: 14.2;Squamous epithelial cells: 19.6;Thymic epithelial cells: 7.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 36: Non-specific - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.4;dendritic cells: 67.4;Endothelial cells: 80.2;Exocrine glandular cells: 64.5;Langerhans cells: 77.8;Macrophages: 45.1;Schwann cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 374.7;Fibroblasts: 250.2;Leydig cells: 430.4;Oligodendrocyte precursor cells: 478.5;Peritubular cells: 384.7" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 76.7;thyroid cancer: 37.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 139.1;Leydig cells: 161.7;Peritubular cells: 206.1;Sertoli cells: 522.4;Smooth muscle cells: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 30.9;testis cancer: 38.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 54: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" PDSS1 "COQ1, COQ1A, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697701-26746798 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism, Ubiquinone biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.1;lymphoid tissue: 13.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 31.7;Proximal enterocytes: 29.4;Undifferentiated cells: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 32: Neurons - Synaptic function" Cytosol "HPA038032: AB_10670650, HPA042741: AB_2678139" "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 231.5;Langerhans cells: 285.2;Muller glia cells: 295.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" Cytosol "Nucleoplasm, Vesicles" "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "monocytes: 275.0;Plasma cells: 237.5;Squamous epithelial cells: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 83.3" "Cell type enhanced" "Detected in many" "Astrocytes: 101.9;Cardiomyocytes: 88.2;dendritic cells: 108.2;Late spermatids: 161.1;Rod photoreceptor cells: 109.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 20.8;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 8 "dendritic cells: 23.8;granulocytes: 20.8" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "HPA049975: AB_2680977, HPA063575: AB_2685046" "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favorable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (1.86e-2)" PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.7;Endothelial cells: 46.6;Microglial cells: 121.3;Smooth muscle cells: 42.5" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Cancer enhanced" "Detected in many" "Sarcoma: 7.3" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Sinusoid Endothelial cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378649-78425114 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "HPA022526: AB_1855271" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (5.76e-3)" "unprognostic (3.17e-2)" "unprognostic (8.46e-3)" "prognostic favorable (7.33e-5)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (1.16e-5)" "unprognostic (9.94e-2)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 130.8;Inhibitory neurons: 138.3;Langerhans cells: 264.8;Microglial cells: 175.1;Oligodendrocyte precursor cells: 520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 59.6;Langerhans cells: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 75: Myeloid cells - Innate immune response" "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1216.9;Inhibitory neurons: 323.2;Oligodendrocyte precursor cells: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 63: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 30.4;Excitatory neurons: 131.2;Inhibitory neurons: 134.4;Oligodendrocyte precursor cells: 81.8" "Cancer enhanced" "Detected in many" "melanoma: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 5.9;Sarcoma: 10.2;skin cancer: 10.2;testis cancer: 6.1" "Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "Cytokinetic bridge" "CAB034342: AB_2164138, HPA028867: AB_2672802, HPA055368: AB_2682796, HPA066962: AB_2685757" "unprognostic (2.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (7.26e-2)" "unprognostic (9.46e-2)" "unprognostic (3.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (3.70e-1)" "unprognostic (4.10e-6)" "unprognostic (1.76e-3)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (6.48e-3)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.3;Distal enterocytes: 250.2;Extravillous trophoblasts: 189.3;Proximal enterocytes: 184.4;Suprabasal keratinocytes: 357.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 65.1;Endometrial ciliated cells: 31.3;Microglial cells: 112.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skin - Mitotic cells (Skin), Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 56: Neurons - Neuronal signaling" "Cluster 70: Basal prostatic cells - Lipid metabolism" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28644142 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 39.0" "Cell type enhanced" "Detected in many" "Early spermatids: 26.3;Extravillous trophoblasts: 31.4;Late spermatids: 18.7;Proximal enterocytes: 121.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 3.0;eosinophil: 3.0;intermediate monocyte: 4.4;myeloid DC: 5.7;neutrophil: 8.8;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 40 "dendritic cells: 5.7;granulocytes: 8.8;monocytes: 5.0" "Low cancer specificity" "Detected in many" "Kidney - Macrophages, Lung - Neutrophil_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.7;Kupffer cells: 40.2;Macrophages: 42.0;Microglial cells: 38.3;monocytes: 57.5;NK-cells: 23.1;Schwann cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.3" "Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "B-cells: 84.2;Microglial cells: 93.0;NK-cells: 44.5;Plasma cells: 97.6" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 34.8;lymphoma: 123.9;Myeloma: 32.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Intercalated cells, Liver - Hepatocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 490.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Group enriched" "Detected in many" 5 "Adipocytes: 86.7;Astrocytes: 95.5;B-cells: 58.6;Endothelial cells: 58.1;Microglial cells: 127.7;Oligodendrocytes: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 62: B-cells - B-cell activation" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 185.3;Alveolar cells type 1: 320.2;Suprabasal keratinocytes: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Cytosol" "HPA000895: , HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction, Lipid transport, Transport" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 267.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 12 "Adipocytes: 460.8;Endothelial cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Group enriched" "Detected in some" 15 "Leukemia: 10.6;lymphoma: 2.9;ovarian cancer: 7.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 48.4" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 277.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 13.4" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012805 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "HPA012805: AB_1857893" "unprognostic (4.28e-1)" "unprognostic (3.55e-1)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (6.07e-3)" "unprognostic (4.62e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (9.15e-8)" "unprognostic (9.37e-3)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1468.6;Oligodendrocytes: 443.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 606.9;Basal squamous epithelial cells: 471.7;Endometrial ciliated cells: 483.2;Glandular and luminal cells: 557.5;Squamous epithelial cells: 446.1;Suprabasal keratinocytes: 601.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Low cancer specificity" "Detected in many" "Breast - T-cells, Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 14: Endometrium - Transcription regulation" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.7;brain: 41.6" "Cell type enhanced" "Detected in some" "Adipocytes: 8.8;Bipolar cells: 11.1;Cone photoreceptor cells: 6.9;Horizontal cells: 23.7;Muller glia cells: 6.7;Peritubular cells: 8.9;Theca cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "HPA054810: AB_2682609" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-1)" "unprognostic (4.15e-1)" "unprognostic (4.19e-3)" "unprognostic (4.26e-4)" "unprognostic (7.30e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.32e-2)" PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 88.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 137.9;Proximal tubular cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "HPA023204: AB_1855506, HPA027776: AB_10601246" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-2)" "unprognostic (6.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.02e-3)" "unprognostic (7.47e-3)" "unprognostic (8.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.74e-1)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" POLR3GL "flj32422, MGC3200" ENSG00000121851 "RNA polymerase III subunit GL" Q9BT43 1 145964690-145978848 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" HPA027288 Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 18: Non-specific - RNA binding" "Cluster 7: NK-cells - Immune response regulation" "HPA027288: AB_10602119" "prognostic favorable (2.96e-4)" "unprognostic (3.58e-3)" "unprognostic (1.55e-2)" "prognostic favorable (6.52e-5)" "unprognostic (2.88e-1)" "unprognostic (1.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.15e-2)" "unprognostic (2.11e-1)" "unprognostic (5.98e-3)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 212.2;Breast myoepithelial cells: 181.2;Endothelial cells: 211.0;Fibroblasts: 216.2;Smooth muscle cells: 107.9" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 399.4;testis cancer: 440.5" "Kidney - Podocytes, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" "HPA012306, HPA071023" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA012306: AB_1854827, HPA071023: " "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" PPP2R5D "B56D, B56delta" ENSG00000112640 "Protein phosphatase 2 regulatory subunit B'delta" Q14738 6 42984553-43012342 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029045, HPA029046" Approved Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 39: Non-specific - mRNA processing" "Cluster 80: Striated muscle - Unknown function" "Cluster 15: Non-specific - Protein binding" "Cluster 61: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA029045: AB_10598912, HPA029046: AB_10600988" "unprognostic (2.25e-1)" "unprognostic (7.14e-2)" "unprognostic (4.73e-2)" "unprognostic (6.89e-2)" "unprognostic (1.74e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (4.08e-2)" "unprognostic (1.24e-1)" "unprognostic (9.44e-2)" "unprognostic (2.59e-1)" "unprognostic (2.71e-1)" "unprognostic (1.21e-1)" "unprognostic (9.96e-2)" "unprognostic (2.70e-1)" "unprognostic (7.95e-2)" "unprognostic (6.05e-2)" PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 286.7;Langerhans cells: 346.9;Macrophages: 246.2;Schwann cells: 216.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 60.8;Excitatory neurons: 303.3;Inhibitory neurons: 119.3;Microglial cells: 62.9;Oligodendrocyte precursor cells: 109.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" PRIM2 PRIM2A ENSG00000146143 "DNA primase subunit 2" P49643 6 57314805-57646850 "Plasma proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 30.6" "Cell type enhanced" "Detected in all" "Microglial cells: 68.4;Oligodendrocyte precursor cells: 54.4;Oligodendrocytes: 51.4;Prostatic glandular cells: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046566 Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 15: Non-specific - Protein binding" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "HPA046566: AB_2679701" "unprognostic (1.24e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (3.08e-1)" "unprognostic (6.24e-2)" "prognostic unfavorable (3.44e-5)" "unprognostic (2.31e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.00e-5)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.89e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (2.04e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" PRIMPOL "CCDC111, FLJ33167" ENSG00000164306 "Primase and DNA directed polymerase" Q96LW4 4 184649667-184694963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.0" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054372 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol Nucleoplasm "HPA054372: AB_2682466" "unprognostic (1.68e-1)" "unprognostic (1.27e-3)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (2.67e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-2)" "unprognostic (3.34e-2)" "unprognostic (3.32e-3)" "unprognostic (5.86e-2)" "unprognostic (2.52e-2)" "unprognostic (5.02e-1)" "unprognostic (3.04e-1)" "unprognostic (3.04e-2)" "unprognostic (3.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.05e-1)" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 260.9;NK-cells: 221.1;T-cells: 121.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" PRLR ENSG00000113494 "Prolactin receptor" P16471 5 35048756-35230487 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "choroid plexus: 781.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 59.7;Breast glandular cells: 72.3;Endometrial stromal cells: 109.1;Granulosa cells: 92.6;Proximal tubular cells: 47.1;Syncytiotrophoblasts: 65.8" "Cancer enriched" "Detected in many" 9 "breast cancer: 20.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "breast cancer: 32.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "unprognostic (3.81e-2)" "unprognostic (2.41e-1)" "unprognostic (2.37e-2)" "unprognostic (6.04e-2)" "unprognostic (5.05e-2)" "unprognostic (8.21e-2)" "unprognostic (3.99e-2)" "unprognostic (7.94e-2)" "unprognostic (4.89e-2)" "unprognostic (1.67e-3)" "unprognostic (4.84e-4)" "unprognostic (2.50e-3)" "unprognostic (4.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (9.84e-5)" "unprognostic (1.24e-1)" PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 38.5;Club cells: 53.2;Ionocytes: 50.1;Squamous epithelial cells: 40.2;Suprabasal keratinocytes: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 77.9;head and neck cancer: 88.1" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" PRR33 "C11orf89, LOC728008" ENSG00000283787 "Proline rich 33" 11 1888078-1891895 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.4;lymphoid tissue: 28.3;skeletal muscle: 35.2" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Group enriched" "Detected in some" 13 "Leukemia: 1.6;lymphoma: 5.7;Myeloma: 2.6" "Adipose subcutaneous - Adipose progenitor cells, Kidney - T-cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 27: Skeletal myocytes - Muscle contraction" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 151.2;Club cells: 243.7;Ductal cells: 107.1;Ionocytes: 452.1;Respiratory ciliated cells: 117.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 23.8" "Colon - Colon enterocytes, Kidney - Endothelial cells, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 249.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 352.6;Club cells: 331.2;Endothelial cells: 345.4;Granulosa cells: 344.5;Ionocytes: 367.6;Theca cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.6" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.6" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" NA NA 440000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 5: Bronchus - Unknown function" "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 39 "Muller glia cells: 336.3" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Group enriched" "Detected in many" 5 "Bone cancer: 40.4;Brain cancer: 17.0;testis cancer: 17.9" "Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: Bone cancer - Transcription" "Cluster 68: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.4;Hofbauer cells: 16.9;Proximal enterocytes: 48.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favorable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "brain: 22.6" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 1.7;Early spermatids: 3.8;Horizontal cells: 2.6;Late spermatids: 5.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 12 "cerebellum: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 2.2;Myeloma: 7.6;Rhabdoid: 4.4" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 24: Spermatids - Unknown function" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 54.7;Kupffer cells: 54.0;Langerhans cells: 38.0;Macrophages: 41.3;monocytes: 32.9;NK-cells: 72.7;T-cells: 64.7;Theca cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 13.3;lymphoma: 11.8" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.9;lymphoid tissue: 6.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 16.4;NK-cells: 118.8;T-cells: 29.8;Undifferentiated cells: 27.6" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 68.0;NK-cell: 90.3" "Group enriched" "Detected in many" 33 "NK-cells: 90.3;T-cells: 68.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.8" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Stomach - Fibroblasts, Thyroid - T-cells" "Low region specificity" "Detected in some" HPA049668 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 31099.3;Peritubular cells: 49871.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 79.7;ovarian cancer: 30.2" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 278.5;liver: 594.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 423.5;Hepatocytes: 990.0;Proximal enterocytes: 1250.7;Proximal tubular cells: 461.3;Suprabasal keratinocytes: 865.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 5.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 5.9" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 2400000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favorable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: Non-specific - Transcription" "Cluster 19: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity, Lipid metabolism" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Cell type enhanced" "Detected in many" "B-cells: 57.0;granulocytes: 38.6;NK-cells: 204.4;T-cells: 143.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 15.4;lymphoma: 22.3;Myeloma: 12.6" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 208.8;Endothelial cells: 225.2;Inhibitory neurons: 67.1;Microglial cells: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 11.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 506.7;Kupffer cells: 464.5;Macrophages: 507.9;monocytes: 1400.2;NK-cells: 1356.4;T-cells: 1034.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 117.5;lymphoma: 158.9" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" PYGO1 ENSG00000171016 "Pygopus family PHD finger 1" Q9Y3Y4 15 55538884-55588947 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 22.8;Inhibitory neurons: 29.7;Oligodendrocyte precursor cells: 57.3;Prostatic glandular cells: 19.0;Skeletal myocytes: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042248 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm Cytosol "HPA042248: AB_10794272" "unprognostic (5.55e-2)" "unprognostic (9.82e-2)" "unprognostic (2.61e-2)" "unprognostic (4.54e-2)" "unprognostic (7.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (2.29e-1)" "unprognostic (6.72e-6)" "unprognostic (3.36e-4)" "unprognostic (4.84e-2)" "unprognostic (2.30e-2)" "unprognostic (1.80e-2)" RAB27A "GS2, HsT18676, RAB27, RAM" ENSG00000069974 "RAB27A, member RAS oncogene family" P51159 15 55202966-55319113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Exocytosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 119.9" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 123.0;Intestinal goblet cells: 262.0;Melanocytes: 106.2;NK-cells: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 261.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001333, CAB034046" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 37: Intestine - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 26: Intestinal epithelial cells - Absorption" "CAB034046: AB_2176724, HPA001333: AB_1079730" "prognostic favorable (2.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (2.77e-1)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.23e-2)" "unprognostic (4.34e-1)" "unprognostic (7.95e-3)" "unprognostic (4.32e-1)" RAB3B ENSG00000169213 "RAB3B, member RAS oncogene family" P20337 1 51907956-51990700 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 31.0;pituitary gland: 10.6;prostate: 11.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 125.1;Inhibitory neurons: 46.9;Pancreatic endocrine cells: 51.5;Prostatic glandular cells: 124.7" "Group enriched" "Detected in many" 6 "prostate cancer: 19.4;testis cancer: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 24.6" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003159, CAB023293" Enhanced Approved "Cell Junctions" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 55: Endocrine cells - Hormone signaling" "Cell Junctions" "CAB023293: , HPA003159: AB_1856005" "unprognostic (1.10e-1)" "unprognostic (2.20e-3)" "unprognostic (5.43e-3)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (1.38e-2)" "unprognostic (1.20e-2)" "unprognostic (8.77e-3)" "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-2)" "unprognostic (2.02e-3)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;breast: 2.5;parathyroid gland: 3.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.4;Oligodendrocytes: 3.1" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;prostate cancer: 1.3" "Breast - Breast glandular cells, Kidney - Podocytes, Prostate - Prostate glandular cells" HPA059131 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 65: Breast cancer - Unknown function" "Cluster 12: Non-specific - Chromatin organization" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (8.62e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-1)" RADIL "FLJ10324, KIAA1849, RASIP2" ENSG00000157927 "Rap associating with DIL domain" Q96JH8 7 4797055-4883716 "Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0" "Cell type enhanced" "Detected in many" "Astrocytes: 9.8;Early spermatids: 10.7;Horizontal cells: 12.2;Melanocytes: 12.2;Microglial cells: 13.7;Spermatocytes: 15.0;Spermatogonia: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.8" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051776 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear membrane" "HPA051776: AB_2681605" "unprognostic (6.77e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.80e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "unprognostic (9.74e-4)" "unprognostic (4.63e-2)" "unprognostic (3.48e-1)" "unprognostic (2.83e-2)" "unprognostic (7.89e-4)" "unprognostic (5.32e-2)" "unprognostic (1.49e-4)" "unprognostic (5.10e-3)" "unprognostic (2.46e-1)" "unprognostic (3.33e-3)" "unprognostic (4.28e-3)" RALYL HNRPCL3 ENSG00000184672 "RALY RNA binding protein like" Q86SE5 8 84182787-84921844 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 19.8;brain: 68.1;kidney: 19.2" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 2787.8" "Cancer enhanced" "Detected in single" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.2;prostate cancer: 3.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055868, HPA059112" Enhanced Enhanced Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA055868: AB_2682950, HPA059112: AB_2683908" "unprognostic (1.13e-5)" "unprognostic (1.62e-1)" "unprognostic (7.48e-2)" "unprognostic (1.36e-1)" "unprognostic (5.04e-2)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (4.82e-5)" "unprognostic (2.74e-2)" "unprognostic (2.52e-1)" RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 4 "Adipocytes: 318.2;Endothelial cells: 301.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Bone cancer: 13.2" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;kidney: 24.6" "Cell type enriched" "Detected in some" 7 "Astrocytes: 344.8" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;glioma: 3.7;prostate cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.6" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 59: Fibroblasts - Metabolism" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA037471: AB_10671756, HPA037472: AB_2675489, HPA061526: AB_2684552" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (5.52e-3)" "unprognostic (2.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (9.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (3.76e-4)" "unprognostic (1.68e-2)" "unprognostic (9.13e-2)" "unprognostic (8.87e-3)" "unprognostic (5.71e-2)" RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 498.0;Inhibitory neurons: 189.6;Microglial cells: 135.0;Oligodendrocytes: 604.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.5;dendritic cells: 22.6;granulocytes: 24.5;monocytes: 31.6;NK-cells: 90.9;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Leukemia: 24.3;lymphoma: 22.6;Myeloma: 28.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;skeletal muscle: 42.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.1;Endothelial cells: 50.7;Exocrine glandular cells: 71.5;Oligodendrocytes: 176.0;Plasma cells: 70.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 13.9;memory B-cell: 12.3;naive B-cell: 15.2" "Group enriched" "Detected in many" 16 "B-cells: 15.2;granulocytes: 13.9" "Group enriched" "Detected in many" 7 "lymphoma: 47.5;Myeloma: 42.1" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058937 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus" "HPA058937: AB_2683858" "unprognostic (2.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (3.90e-1)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (9.96e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "granulocytes: 28.0;Hofbauer cells: 22.7;Kupffer cells: 34.2;Langerhans cells: 15.0;Macrophages: 20.9;monocytes: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Leukemia: 7.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 21.8;Cardiomyocytes: 23.8;Muller glia cells: 21.2;Peritubular cells: 59.2;Schwann cells: 19.6;Sertoli cells: 55.3;Smooth muscle cells: 68.9" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 6.9;testis cancer: 17.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" RASSF5 "Maxp1, NORE1, RAPL" ENSG00000266094 "Ras association domain family member 5" Q8WWW0 1 206507531-206589448 "Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 109.3;lymphoid tissue: 83.1" "Cell type enhanced" "Detected in many" "granulocytes: 150.8;Langerhans cells: 178.3;monocytes: 230.3;NK-cells: 139.9;T-cells: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 48.6;lymphoma: 46.9;Myeloma: 80.7" "Adipose subcutaneous - Adipose progenitor cells, Kidney - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070480 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA070480: AB_2686271" "unprognostic (1.92e-3)" "prognostic favorable (1.46e-4)" "unprognostic (1.37e-2)" "unprognostic (4.44e-3)" "unprognostic (1.93e-1)" "unprognostic (5.17e-3)" "unprognostic (4.19e-2)" "unprognostic (3.95e-2)" "unprognostic (2.79e-1)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (1.22e-6)" "unprognostic (3.29e-1)" "unprognostic (5.58e-2)" "unprognostic (4.28e-2)" "unprognostic (6.28e-3)" RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 119.4;Spermatocytes: 124.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.2;Enteroendocrine cells: 58.0;Intestinal goblet cells: 60.9;Paneth cells: 53.6;Proximal enterocytes: 151.7;Undifferentiated cells: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.2" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042627 Approved Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nucleoplasm, Vesicles" "HPA042627: AB_10797504" "unprognostic (8.99e-2)" "unprognostic (6.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-3)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.91e-4)" RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 73.9;heart muscle: 25.2;skeletal muscle: 95.3;tongue: 45.3" "Group enriched" "Detected in many" 8 "Excitatory neurons: 5717.8;Inhibitory neurons: 5786.0" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Group enriched" "Detected in many" 10 "basal ganglia: 28.1;cerebral cortex: 73.9;hippocampal formation: 26.6;white matter: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.2;Neuroblastoma: 4.3;Sarcoma: 4.4" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: AB_10796228, HPA066746: , HPA075862: " "unprognostic (3.75e-3)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (5.19e-3)" "unprognostic (8.82e-5)" "unprognostic (5.02e-1)" "unprognostic (3.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.23e-1)" "unprognostic (5.00e-2)" "unprognostic (2.28e-1)" RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.1;Inhibitory neurons: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "HPA054962: AB_2682652, HPA056525: AB_2683165" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-2)" "unprognostic (3.70e-3)" "unprognostic (2.13e-1)" "unprognostic (1.51e-1)" "unprognostic (6.25e-5)" "unprognostic (6.91e-2)" "unprognostic (7.19e-3)" "unprognostic (1.20e-1)" "unprognostic (4.49e-3)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (3.15e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" RBM11 ENSG00000185272 "RNA binding motif protein 11" P57052 21 14216130-14228372 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "epididymis: 45.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 18.7;Early spermatids: 11.0;Excitatory neurons: 12.8;Inhibitory neurons: 14.4;Spermatogonia: 10.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.2" "Lineage enriched" "Detected in single" 10 "T-cells: 1.2" "Cancer enriched" "Detected in some" 27 "Bone cancer: 28.8" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045885 Supported Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "HPA045885: AB_10963937" "unprognostic (1.95e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-1)" "unprognostic (5.44e-4)" "unprognostic (2.18e-1)" "unprognostic (7.97e-2)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "unprognostic (3.23e-2)" "unprognostic (9.92e-4)" "unprognostic (5.74e-2)" "unprognostic (1.16e-4)" "unprognostic (3.45e-2)" "unprognostic (4.81e-2)" "unprognostic (2.69e-1)" "unprognostic (9.24e-3)" RBM44 FLJ40411 ENSG00000177483 "RNA binding motif protein 44" Q6ZP01 2 237798389-237842808 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 15.7" "Group enriched" "Detected in some" 4 "Spermatocytes: 109.2;Spermatogonia: 48.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Kidney - Endothelial cells, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003298 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA003298: AB_2284846" "unprognostic (1.29e-1)" "unprognostic (2.66e-1)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "unprognostic (8.47e-3)" "unprognostic (3.15e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (1.83e-2)" "unprognostic (8.12e-2)" "unprognostic (4.10e-2)" "unprognostic (4.57e-2)" "unprognostic (5.01e-5)" "unprognostic (1.90e-1)" "unprognostic (4.27e-2)" "unprognostic (6.85e-3)" "unprognostic (7.89e-3)" RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 437.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 18: Non-specific - Mixed function" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Cell type enhanced" "Detected in many" "Ductal cells: 937.0;Endometrial stromal cells: 1067.0;Exocrine glandular cells: 869.9;Granulosa cells: 5685.6;Theca cells: 2489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 282.2" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Leydig cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: DU4475 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" RCBTB2 CHC1L ENSG00000136161 "RCC1 and BTB domain containing protein 2" O95199 13 48488963-48533256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 25.5" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040242 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 12: Non-specific - Chromatin organization" "Nucleoplasm, Golgi apparatus" "HPA040242: AB_10795362" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (8.47e-2)" "unprognostic (9.47e-3)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-1)" "unprognostic (5.40e-3)" "unprognostic (8.28e-3)" "unprognostic (1.20e-1)" "unprognostic (4.85e-2)" "unprognostic (3.60e-1)" "prognostic favorable (2.45e-4)" "unprognostic (1.06e-2)" "unprognostic (8.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.98e-1)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.5;Proximal enterocytes: 36.2;Rod photoreceptor cells: 73.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" REPS2 POB1 ENSG00000169891 "RALBP1 associated Eps domain containing 2" Q8NFH8 X 16946658-17153272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 116.3;Inhibitory neurons: 139.2;Oligodendrocyte precursor cells: 81.3;Oligodendrocytes: 192.6" "Cancer enhanced" "Detected in all" "prostate cancer: 13.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "basophil: 5.8;eosinophil: 4.5;neutrophil: 14.3" "Lineage enriched" "Detected in single" 28 "granulocytes: 14.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000565, HPA026073" Uncertain "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA000565: AB_1079800, HPA026073: AB_1856176" "unprognostic (6.58e-2)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (7.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.70e-3)" "prognostic favorable (5.36e-4)" "unprognostic (4.85e-2)" "unprognostic (2.87e-2)" "unprognostic (5.53e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (1.83e-1)" "prognostic favorable (4.08e-4)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (2.43e-2)" "prognostic favorable (4.56e-4)" RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 93.8" "Cell type enhanced" "Detected in many" "Late spermatids: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 6: Late spermatids - Spermatogenesis" Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favorable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 138.9;Basal squamous epithelial cells: 44.6;Leydig cells: 118.0;Peritubular cells: 115.2;Skeletal myocytes: 51.5;Spermatogonia: 46.2;Squamous epithelial cells: 59.2" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.9;Sarcoma: 9.5" "Kidney - Fibroblasts, Lung - Fibroblast_2, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" RGPD8 "RanBP2alpha, RANBP2L1" ENSG00000169629 "RANBP2 like and GRIP domain containing 8" O14715 2 112368369-112434488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 15.6" "Cell type enhanced" "Detected in some" "Early spermatids: 18.0;Excitatory neurons: 9.7;Inhibitory neurons: 6.9;Late spermatids: 12.9;Microglial cells: 9.1;Oligodendrocyte precursor cells: 7.2;Spermatocytes: 6.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 61: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (3.62e-1)" "unprognostic (7.61e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-3)" "unprognostic (3.17e-3)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" "unprognostic (2.57e-1)" "unprognostic (9.18e-3)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" RGS1 "1R20, BL34, IER1, IR20" ENSG00000090104 "Regulator of G protein signaling 1" Q08116 1 192575763-192580024 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 496.4;granulocytes: 1099.8;Hofbauer cells: 391.3;Langerhans cells: 1304.4;Macrophages: 662.0;Plasma cells: 677.2;Schwann cells: 793.9;T-cells: 630.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 25.7;T-reg: 21.9" "Group enriched" "Detected in many" 5 "granulocytes: 25.7;T-cells: 21.9" "Cancer enhanced" "Detected in some" "lymphoma: 74.7;Myeloma: 129.8" "Kidney - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 85.5" HPA074572 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA074572: " "unprognostic (3.68e-3)" "unprognostic (1.14e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-1)" "unprognostic (4.37e-1)" "unprognostic (3.87e-3)" "unprognostic (6.61e-2)" "unprognostic (1.38e-1)" "unprognostic (3.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (4.91e-5)" "prognostic unfavorable (9.57e-4)" "unprognostic (4.01e-2)" "unprognostic (9.90e-2)" "unprognostic (4.56e-2)" RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 452.7;Sertoli cells: 1998.5;Smooth muscle cells: 1501.8" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 848.3" "Adipose subcutaneous - Endothelial cells, Kidney - Fibroblasts, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" RGS7 ENSG00000182901 "Regulator of G protein signaling 7" P49802 1 240775514-241357230 "Plasma proteins, Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.0;brain: 28.1;retina: 12.8" "Cell type enhanced" "Detected in some" "Astrocytes: 279.3;Excitatory neurons: 1333.7;Inhibitory neurons: 1068.0;Oligodendrocyte precursor cells: 589.7" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Intercalated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017561 Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 32: Neurons - Synaptic function" Cytosol Mitochondria "CAB017561: AB_2285043" "unprognostic (6.48e-2)" "unprognostic (4.30e-2)" "unprognostic (4.67e-2)" "unprognostic (6.65e-2)" "unprognostic (7.84e-3)" "unprognostic (4.09e-2)" "unprognostic (1.49e-2)" "unprognostic (3.61e-1)" "unprognostic (1.42e-2)" "unprognostic (2.51e-4)" "unprognostic (3.54e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (2.28e-1)" RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 120.6;Horizontal cells: 30.8;Inhibitory neurons: 166.4;Oligodendrocyte precursor cells: 65.0" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.5;Astrocytes: 170.5;Endothelial cells: 70.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;skin cancer: 36.2" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" RHOU "ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1" ENSG00000116574 "Ras homolog family member U" Q7L0Q8 1 228735479-228746664 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 114.6;Endometrial stromal cells: 98.3;Extravillous trophoblasts: 101.9;Oligodendrocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049592 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 6: BEWO - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "HPA049592: AB_2680827" "unprognostic (7.90e-2)" "unprognostic (1.18e-2)" "unprognostic (1.76e-2)" "unprognostic (8.26e-3)" "unprognostic (3.26e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (6.21e-2)" "prognostic favorable (3.56e-5)" "unprognostic (4.20e-1)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" "unprognostic (1.87e-2)" RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.3;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 25.1;monocytes: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" RIPPLY3 DSCR6 ENSG00000183145 "Ripply transcriptional repressor 3" P57055 21 37006150-37019662 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.0;Extravillous trophoblasts: 2.8;Prostatic glandular cells: 1.8;Squamous epithelial cells: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" HPA055541 Uncertain NA NA "Cluster 41: Non-specific - Cilium assembly" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA055541: AB_2682840" "unprognostic (1.77e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-3)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.91e-2)" "unprognostic (2.11e-2)" "unprognostic (2.17e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-2)" "unprognostic (3.58e-1)" "unprognostic (2.31e-1)" "unprognostic (1.57e-4)" "unprognostic (2.69e-1)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 133.7;dendritic cells: 427.9;Hofbauer cells: 263.8;Kupffer cells: 391.5;Langerhans cells: 225.3;Macrophages: 270.2;Schwann cells: 226.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 22.4;lymphoma: 7.3;Myeloma: 9.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 318.2;Langerhans cells: 339.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 57: Non-specific - Translation" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808067-61894247 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.3;choroid plexus: 62.3;kidney: 56.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 84.9;Proximal tubular cells: 141.1;Salivary duct cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favorable (1.13e-8)" "prognostic unfavorable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" RNF183 MGC4734 ENSG00000165188 "Ring finger protein 183" Q96D59 9 113297093-113303376 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.4;kidney: 11.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 16.1;Endometrial ciliated cells: 11.1;Enteroendocrine cells: 9.3;Glandular and luminal cells: 17.3;Ionocytes: 32.2;Proximal tubular cells: 25.9;Respiratory ciliated cells: 12.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.1" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057675 Uncertain NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "HPA057675: AB_2683499" "unprognostic (1.23e-2)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.95e-6)" "unprognostic (2.56e-1)" "unprognostic (1.75e-2)" "unprognostic (1.54e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.51e-4)" "unprognostic (5.50e-2)" "unprognostic (8.84e-2)" "unprognostic (9.61e-2)" "unprognostic (2.53e-3)" ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3385.3;Inhibitory neurons: 4585.4" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Podocytes, Lung - Fibroblast_1, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" RTL5 "KIAA2001, Mar5, Mart5, RGAG4, SIRH8" ENSG00000242732 "Retrotransposon Gag like 5" Q5HYW3 X 72127110-72131901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 7.2" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 12.1;granulocytes: 11.4;Sertoli cells: 13.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.4" "Region enhanced" "Detected in many" "cerebellum: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.2" "Kidney - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003652 Approved Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 11: Non-specific - Transcription" Nucleoplasm "HPA003652: AB_1079805" "unprognostic (7.97e-2)" "unprognostic (1.31e-2)" "unprognostic (5.29e-3)" "unprognostic (2.98e-2)" "unprognostic (3.93e-2)" "unprognostic (3.64e-1)" "unprognostic (4.20e-1)" "prognostic favorable (7.30e-4)" "unprognostic (1.62e-1)" "unprognostic (2.82e-1)" "prognostic favorable (3.41e-4)" "unprognostic (4.23e-1)" "unprognostic (4.18e-3)" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-2)" RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 147.2;NK-cells: 443.6;T-cells: 232.6" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bone cancer: 17.8;Leukemia: 19.3;lymphoma: 47.9;Myeloma: 36.7;skin cancer: 28.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.3;brain: 7.6;endometrium 1: 6.2" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 57.1;Excitatory neurons: 165.1;Glandular and luminal cells: 164.3" "Cancer enriched" "Detected in single" 9 "endometrial cancer: 3.9" "Group enriched" "Detected in many" 4 "amygdala: 4.6;basal ganglia: 5.3;cerebral cortex: 7.6;hippocampal formation: 4.6;white matter: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 33.3;Uterine cancer: 13.6" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 11.8;hippocampal formation: 7.8" HPA027067 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 38: Neurons - Neuronal signaling" "HPA027067: AB_10602127" "unprognostic (3.07e-3)" "unprognostic (3.02e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-3)" "unprognostic (6.13e-2)" "unprognostic (6.18e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-6)" "unprognostic (8.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.33e-4)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (6.22e-3)" S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 973.9;Squamous epithelial cells: 1202.5;Suprabasal keratinocytes: 2430.8;Theca cells: 1030.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.7;Ductal cells: 18.4;Endometrial stromal cells: 20.2;Exocrine glandular cells: 13.4;Ionocytes: 10.5;Pancreatic endocrine cells: 12.0" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.2;plasmacytoid DC: 7.4" "Group enriched" "Detected in many" 11 "dendritic cells: 7.4;monocytes: 6.2" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.8" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" SALL3 ZNF796 ENSG00000256463 "Spalt like transcription factor 3" Q9BXA9 18 78980275-79002677 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;prostate: 6.0;vagina: 8.0" "Group enriched" "Detected in some" 4 "Astrocytes: 24.7;Bipolar cells: 13.5;Cone photoreceptor cells: 32.7;Horizontal cells: 12.2;Oligodendrocyte precursor cells: 20.2" "Cancer enriched" "Detected in some" 6 "glioma: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;testis cancer: 1.6" "Kidney - Intercalated cells, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.5" "Low region specificity" "Detected in many" HPA016656 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA016656: AB_1856546" "unprognostic (3.96e-2)" "unprognostic (3.41e-3)" "unprognostic (8.16e-2)" "unprognostic (1.87e-2)" "unprognostic (2.37e-1)" "unprognostic (4.23e-1)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (5.86e-3)" SAMD11 MGC45873 ENSG00000187634 "Sterile alpha motif domain containing 11" Q96NU1 1 923923-944575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 61.3" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030110 Approved Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "HPA030110: " "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (4.11e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-2)" "unprognostic (2.42e-1)" "unprognostic (9.28e-2)" "unprognostic (6.90e-2)" "unprognostic (3.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.35e-5)" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.26e-2)" "unprognostic (1.18e-1)" SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 5 "NK-cells: 253.7;T-cells: 72.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - Alpha cells, Prostate - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 7: NK-cells - Immune response regulation" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.3;Endothelial cells: 47.7;Langerhans cells: 45.1;Microglial cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Group enriched" "Detected in many" 7 "B-cells: 78.9;Hofbauer cells: 42.8;Kupffer cells: 89.4;Macrophages: 63.9;monocytes: 119.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cancer enhanced" "Detected in many" "lymphoma: 15.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.1;lymphoid tissue: 12.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.2;Late spermatids: 173.4;NK-cells: 47.2;Serous glandular cells: 29.8;T-cells: 87.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 48.2;MAIT T-cell: 47.7;memory CD4 T-cell: 74.8;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.1;naive CD8 T-cell: 59.5;NK-cell: 53.2" "Group enriched" "Detected in many" 6 "NK-cells: 53.2;T-cells: 74.8" "Cancer enhanced" "Detected in some" "skin cancer: 9.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA063326: AB_2684986, HPA065958: AB_2685587" "unprognostic (4.00e-5)" "unprognostic (2.10e-3)" "unprognostic (4.71e-2)" "unprognostic (4.24e-3)" "unprognostic (1.38e-3)" "unprognostic (4.75e-4)" "unprognostic (3.84e-3)" "unprognostic (6.65e-3)" "unprognostic (4.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-4)" "unprognostic (3.68e-1)" "unprognostic (3.77e-4)" "unprognostic (8.65e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-3)" "unprognostic (5.09e-3)" SCRN2 ENSG00000141295 "Secernin 2" Q96FV2 17 47837692-47841289 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Proximal enterocytes: 141.1;Proximal tubular cells: 256.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022934, HPA023434" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA 370000 "Cluster 44: Non-specific - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "Golgi apparatus" "HPA022934: AB_1856638, HPA023434: AB_1856639" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (2.86e-1)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (1.73e-1)" "prognostic favorable (3.86e-4)" "unprognostic (4.63e-2)" "unprognostic (3.25e-2)" "unprognostic (5.77e-2)" "unprognostic (1.28e-3)" "unprognostic (8.72e-2)" "unprognostic (3.43e-2)" "unprognostic (5.28e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "prognostic favorable (5.83e-4)" SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 538.0;Proximal tubular cells: 804.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: Non-specific - RNA binding" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (1.48e-2)" "unprognostic (6.88e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-2)" "unprognostic (1.90e-2)" "unprognostic (5.02e-2)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" "unprognostic (7.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.20e-4)" "unprognostic (9.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.19e-3)" "unprognostic (3.77e-1)" SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891962 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 1375.7;Langerhans cells: 2779.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 471.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 471.4" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "HPA008196: AB_1856665" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-1)" "prognostic favorable (7.18e-4)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.02e-2)" "prognostic favorable (3.76e-4)" "unprognostic (2.75e-1)" "unprognostic (5.21e-2)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-2)" "unprognostic (8.43e-2)" "unprognostic (8.12e-2)" "unprognostic (9.35e-2)" "unprognostic (2.56e-3)" SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 295.4;Kupffer cells: 92.0;Macrophages: 68.4;monocytes: 178.2;NK-cells: 166.0;T-cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 33 "Leukemia: 71.3;lymphoma: 66.0;Myeloma: 244.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: BEWO - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.2;Hepatocytes: 46.6;Intestinal goblet cells: 39.0;Paneth cells: 38.3;Proximal enterocytes: 46.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Cell type enriched" "Detected in many" 7 "Oligodendrocyte precursor cells: 1139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 13000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA004632: AB_1079905" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "unprognostic (6.67e-2)" "unprognostic (3.65e-1)" "prognostic favorable (2.45e-4)" "unprognostic (7.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (8.15e-2)" "prognostic favorable (3.66e-8)" "unprognostic (8.51e-3)" "unprognostic (1.27e-2)" "unprognostic (3.57e-1)" "unprognostic (3.01e-2)" SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 37.8;Endothelial cells: 39.8;Excitatory neurons: 30.2;Horizontal cells: 26.9;Inhibitory neurons: 29.6;Macrophages: 20.5;Oligodendrocyte precursor cells: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 50.0" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 66: Endothelial cells - Angiogenesis" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5;Cone photoreceptor cells: 86.2;Excitatory neurons: 118.8;Granulosa cells: 69.6;Inhibitory neurons: 313.3;Oligodendrocytes: 132.3" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 14.2" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 47: Retina - Visual perception" "Cluster 32: Neurons - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in many" "B-cells: 98.3;NK-cells: 87.5;T-cells: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 58 "Leukemia: 27.5;lymphoma: 32.6;Myeloma: 19.8" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 669.4;Exocrine glandular cells: 626.5;Suprabasal keratinocytes: 727.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 74: Pancreatic cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 167.6;Excitatory neurons: 174.3;Inhibitory neurons: 224.1;Muller glia cells: 73.2;Oligodendrocytes: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "thyroid cancer: 71.2" "Heart muscle - Smooth muscle cells, Kidney - Proximal tubular cells, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 2: DU4475 - Unknown function" "Cluster 35: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" SERPINI2 "MEPI, PANCPIN, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441789-167479004 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "pancreas: 1370.0" "Cell type enhanced" "Detected in some" "Astrocytes: 36.4;Exocrine glandular cells: 25.5;Respiratory ciliated cells: 109.4" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.1" "Kidney - Podocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Secreted to digestive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 20: Airway & Pancreas - Proteolysis" "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" SESN3 "MGC29667, SEST3" ENSG00000149212 "Sestrin 3" P58005 11 95165513-95232541 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 673.4;Late spermatids: 599.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "testis cancer: 110.9" "Kidney - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037935 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 49: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA037935: AB_10670534" "unprognostic (2.72e-2)" "unprognostic (3.06e-1)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (5.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.18e-1)" "unprognostic (8.19e-3)" "unprognostic (1.38e-1)" "unprognostic (3.78e-1)" "unprognostic (2.34e-3)" "unprognostic (4.43e-2)" "unprognostic (1.67e-3)" "unprognostic (1.69e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-2)" "unprognostic (9.42e-2)" SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 343.9;Inhibitory neurons: 536.3;Oligodendrocyte precursor cells: 163.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 57: Non-specific - Translation" "Cluster 1: T-cells - Immune response" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.6" "Cell type enhanced" "Detected in all" "Astrocytes: 392.5;Late spermatids: 191.3" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "dendritic cells: 216.4;Kupffer cells: 84.7;Langerhans cells: 142.9;Macrophages: 95.1;monocytes: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 8 "NK-cells: 146.9;T-cells: 98.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Cancer enriched" "Detected in some" 4 "Leukemia: 38.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 48.6;dendritic cells: 36.0;Endothelial cells: 52.0;Microglial cells: 22.8;monocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 33.7;lymphoma: 25.7;Myeloma: 27.6;Neuroblastoma: 16.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" SH3PXD2A "FISH, KIAA0418, SH3MD1" ENSG00000107957 "SH3 and PX domains 2A" Q5TCZ1 10 103594027-103855543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037922, HPA037923" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA037922: AB_10697088, HPA037923: AB_10672612" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-2)" "unprognostic (3.00e-2)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.83e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (1.25e-1)" "unprognostic (2.59e-1)" "unprognostic (5.78e-3)" "unprognostic (2.62e-2)" SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 17.8;Extravillous trophoblasts: 30.5;Plasma cells: 56.0;Spermatocytes: 35.3;Spermatogonia: 21.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 40: Plasma cells - Humoral immune response" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" SHF ENSG00000138606 "Src homology 2 domain containing F" Q7M4L6 15 45167214-45201175 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.7;Granulosa cells: 56.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 143.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 42.6" "Kidney - Fibroblasts, Skin - Outer root sheath cells" "Region enriched" "Detected in all" 5 "cerebellum: 240.6" "Region enriched" "Detected in all" 4 "cerebellum: 106.2" HPA057381 Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA057381: AB_2683423" "unprognostic (4.05e-2)" "unprognostic (2.02e-3)" "unprognostic (7.59e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" "unprognostic (7.61e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (6.88e-2)" "unprognostic (5.12e-2)" "unprognostic (6.89e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (5.09e-3)" "unprognostic (1.83e-2)" SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 121.3;Oligodendrocytes: 437.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 4.5;testis cancer: 3.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" SIAH3 FLJ39203 ENSG00000215475 "Siah E3 ubiquitin protein ligase family member 3" Q8IW03 13 45777242-45851753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;fallopian tube: 3.1" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 26.5;Horizontal cells: 10.9;Inhibitory neurons: 34.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.5;ovarian cancer: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Bone cancer: 3.1" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060576 Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 21: Non-specific - Transcription" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 37: Neurons - Neuronal signaling" Mitochondria Nucleoplasm "HPA060576: AB_2684325" "unprognostic (1.07e-3)" "unprognostic (1.26e-1)" "unprognostic (3.00e-2)" "unprognostic (1.14e-1)" "unprognostic (4.96e-2)" "unprognostic (1.00e-2)" "unprognostic (1.05e-1)" "unprognostic (7.53e-2)" "unprognostic (3.24e-4)" "unprognostic (1.11e-1)" "unprognostic (4.77e-3)" "unprognostic (3.24e-3)" "unprognostic (9.03e-4)" "unprognostic (2.03e-1)" "unprognostic (2.18e-1)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Hofbauer cells: 77.2;Macrophages: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 31.1;kidney: 61.3" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 86.2;Squamous epithelial cells: 60.4" "Cancer enhanced" "Detected in many" "prostate cancer: 11.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 38.8" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.2" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 7: Kidney - Transmembrane transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA029295: AB_10610425" "unprognostic (1.17e-3)" "unprognostic (6.46e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (8.62e-2)" "unprognostic (1.43e-2)" "unprognostic (8.30e-2)" "unprognostic (5.46e-3)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-3)" "unprognostic (9.18e-2)" "unprognostic (9.18e-7)" "unprognostic (2.98e-2)" "unprognostic (3.79e-2)" "unprognostic (1.07e-2)" "prognostic favorable (2.88e-4)" SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6" "Cell type enhanced" "Detected in many" "Microglial cells: 178.8;Schwann cells: 107.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: Skin cancer - Membrane components" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" SIRPG "bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma" ENSG00000089012 "Signal regulatory protein gamma" Q9P1W8 20 1629152-1657779 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 39.1" "Group enriched" "Detected in some" 4 "Early spermatids: 63.4;T-cells: 39.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 369.4" "Lineage enriched" "Detected in many" 6 "T-cells: 369.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;ovarian cancer: 2.2;thyroid cancer: 4.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.35e-3)" "unprognostic (4.09e-3)" "unprognostic (7.32e-3)" "prognostic favorable (1.05e-6)" "unprognostic (4.23e-3)" "prognostic favorable (2.24e-4)" "unprognostic (4.49e-2)" "unprognostic (1.30e-2)" "prognostic favorable (7.36e-7)" "unprognostic (1.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.40e-2)" "unprognostic (2.95e-3)" SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 29.1;NK-cells: 133.2;T-cells: 52.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Cancer enriched" "Detected in some" 8 "Leukemia: 14.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" SLC12A3 NCCT ENSG00000070915 "Solute carrier family 12 member 3" P55017 16 56865207-56915850 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "kidney: 101.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.9;dendritic cells: 21.1;Glandular and luminal cells: 4.3" "Cancer enhanced" "Detected in some" "renal cancer: 2.5" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 14.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 14.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 9.7;Uterine cancer: 6.7" "Kidney - Intercalated cells, Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA028748 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "HPA028748: AB_10603886" "unprognostic (1.54e-3)" "unprognostic (7.09e-5)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "unprognostic (2.91e-1)" "unprognostic (2.38e-4)" "unprognostic (1.81e-1)" "unprognostic (9.70e-2)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (6.84e-2)" "unprognostic (1.83e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.38e-1)" "unprognostic (1.40e-2)" "unprognostic (1.70e-1)" SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.7;skeletal muscle: 41.2" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 46.7;Macrophages: 35.3;Melanocytes: 67.9;Skeletal myocytes: 90.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Stomach - Chief cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 75: Myeloid cells - Innate immune response" "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 16.4;Excitatory neurons: 18.3;Inhibitory neurons: 20.6;Microglial cells: 43.8;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" SLC1A1 "EAAC1, EAAT3" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 45.0;intestine: 64.7;kidney: 51.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.0;Glandular and luminal cells: 122.1;Hepatocytes: 58.4;Inhibitory neurons: 48.9;Microglial cells: 65.7;Oligodendrocyte precursor cells: 154.5;Proximal enterocytes: 95.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.7" "Group enriched" "Detected in many" 5 "Erythroid cells: 34.9;Proximal enterocytes: 25.4;Respiratory ciliated cells: 68.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.2" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in all" "CAB015468, HPA036974" Approved Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 56: Ciliated cells - Cilium assembly" Mitochondria "CAB015468: , HPA036974: AB_2732474" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (8.42e-3)" "unprognostic (6.17e-2)" "unprognostic (6.22e-3)" "unprognostic (4.17e-3)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.82e-2)" "unprognostic (1.74e-2)" "unprognostic (2.31e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" "unprognostic (4.06e-2)" SLC25A2 ORNT2 ENSG00000120329 "Solute carrier family 25 member 2" Q9BXI2 5 141302635-141304049 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 6.6" "Group enriched" "Detected in some" 22 "Early spermatids: 21.1;Late spermatids: 10.8;Spermatocytes: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042146 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA042146: AB_2677874" "unprognostic (1.55e-1)" "unprognostic (3.53e-1)" "unprognostic (4.63e-2)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (4.72e-3)" "unprognostic (2.81e-1)" "unprognostic (2.62e-2)" "unprognostic (6.69e-2)" "unprognostic (1.17e-1)" "unprognostic (8.82e-10)" "unprognostic (2.56e-1)" "unprognostic (1.87e-1)" "unprognostic (1.26e-2)" "unprognostic (1.14e-1)" SLC26A1 "EDM4, SAT-1" ENSG00000145217 "Solute carrier family 26 member 1" Q9H2B4 4 979073-993440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 6.0;Excitatory neurons: 4.4;Hepatocytes: 9.5;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 5.3;Proximal enterocytes: 6.7;Proximal tubular cells: 6.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 5.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA041654 Uncertain Approved Microtubules NA NA "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Microtubules "HPA041654: AB_10796350" "unprognostic (1.96e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-1)" "unprognostic (4.91e-2)" "unprognostic (1.74e-1)" "unprognostic (2.67e-4)" "unprognostic (5.13e-2)" "unprognostic (5.82e-2)" "unprognostic (2.16e-1)" "unprognostic (3.88e-2)" "unprognostic (1.53e-3)" "unprognostic (2.92e-2)" "prognostic favorable (1.19e-4)" "unprognostic (1.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.65e-3)" SLC26A5 "DFNB61, PRES" ENSG00000170615 "Solute carrier family 26 member 5" P58743 7 103352730-103446207 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell shape, Hearing" "Motor protein" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.2" "Group enriched" "Detected in some" 4 "Astrocytes: 5.4;Excitatory neurons: 4.1;Fibroblasts: 2.3;Gastric mucus-secreting cells: 7.2;Inhibitory neurons: 3.5;Microglial cells: 6.4;Oligodendrocyte precursor cells: 1.9;Oligodendrocytes: 3.9;Prostatic glandular cells: 4.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "basal ganglia: 10.4" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (3.86e-2)" "unprognostic (5.13e-2)" "unprognostic (6.38e-3)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.56e-4)" "unprognostic (4.21e-3)" "unprognostic (8.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.97e-1)" "unprognostic (3.67e-5)" "unprognostic (3.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.94e-2)" "unprognostic (2.69e-3)" SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 92.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 11.9;Distal enterocytes: 27.5;Intestinal goblet cells: 17.8;Paneth cells: 29.5;Proximal enterocytes: 42.9;Undifferentiated cells: 24.1" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Gastric cancer: 8.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Vesicles "Golgi apparatus" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" SLC2A10 GLUT10 ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 41.0;Intestinal goblet cells: 67.2;Prostatic glandular cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 75 "basophil: 20.9" "Lineage enriched" "Detected in single" 75 "granulocytes: 20.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" SLC35F3 FLJ37712 ENSG00000183780 "Solute carrier family 35 member F3" Q8IY50 1 233904676-234324511 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 478.1;Inhibitory neurons: 211.7;Oligodendrocyte precursor cells: 182.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 35 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 35 "dendritic cells: 3.5" "Low cancer specificity" "Detected in many" "Kidney - Intercalated cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051327, HPA061582" Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoli "HPA051327: AB_2681443, HPA061582: AB_2684563" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-2)" "unprognostic (2.69e-5)" "unprognostic (3.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (3.86e-2)" "unprognostic (9.09e-2)" "unprognostic (1.57e-3)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (3.62e-1)" "unprognostic (3.58e-1)" SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 52.5;Early spermatids: 83.3;Excitatory neurons: 33.5;Inhibitory neurons: 41.4;Spermatocytes: 36.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 57.4;Macrophages: 32.9;monocytes: 20.8;Serous glandular cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 40.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 69: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 136.2;kidney: 649.3;pancreas: 217.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 75.1;Glandular and luminal cells: 97.1;Proximal enterocytes: 222.9;Proximal tubular cells: 223.4" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gastric cancer: 15.1;Kidney cancer: 13.9;ovarian cancer: 11.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 956.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 760.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.2;colorectal cancer: 7.7;Gastric cancer: 2.5" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Cholangiocyte, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Uncertain "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nuclear membrane, Golgi apparatus" "Nucleoplasm, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 8.7;Squamous epithelial cells: 7.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 61: Non-specific - Transcription" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" SLCO1C1 "OATP-F, OATP1, OATP1C1, SLC21A14" ENSG00000139155 "Solute carrier organic anion transporter family member 1C1" Q9NYB5 12 20695332-20753386 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 22.2;choroid plexus: 28.3;pituitary gland: 8.1" "Cell type enriched" "Detected in some" 12 "Astrocytes: 283.1" "Cancer enriched" "Detected in single" 17 "glioma: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "cervical cancer: 1.2" "Kidney - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 40: Non-specific - Enzymes" "Cluster 63: Astrocytes - Nervous system maintenance" "unprognostic (1.15e-1)" "unprognostic (8.18e-4)" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (4.64e-1)" "unprognostic (3.16e-2)" "unprognostic (1.76e-1)" "unprognostic (7.32e-2)" "unprognostic (8.89e-2)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (2.70e-2)" "unprognostic (2.37e-4)" "unprognostic (1.56e-3)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.76e-2)" SLFN12L ENSG00000205045 "Schlafen family member 12 like" Q6IEE8 17 35464249-35487857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 4 "NK-cells: 36.7;T-cells: 14.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;NK-cells: 3.6;T-cells: 1.9" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" HPA024447 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Disease variant, Hypotrichosis, Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Supported "Nucleoplasm,Vesicles,Intermediate filaments" NA NA 19000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "Vesicles, Intermediate filaments" "CAB037276: AB_477083, HPA029981: AB_10602406" "unprognostic (5.34e-2)" "unprognostic (1.99e-2)" "unprognostic (6.27e-2)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.60e-3)" "unprognostic (9.64e-2)" "prognostic favorable (1.26e-6)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (8.32e-3)" "unprognostic (8.50e-2)" SMARCAL1 "HARP, HHARP" ENSG00000138375 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1" Q9NZC9 2 216412414-216483053 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020337 Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "HPA020337: AB_2670410" "unprognostic (4.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-2)" "unprognostic (3.39e-2)" "unprognostic (2.68e-2)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.35e-3)" "unprognostic (3.31e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-1)" "unprognostic (7.46e-2)" "unprognostic (2.00e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.4;kidney: 3.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Collecting duct cells: 2.0;Distal tubular cells: 9.3;Prostatic glandular cells: 1.9;Proximal tubular cells: 6.1;Schwann cells: 4.6" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 1.4" "Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 60: Proximal tubular cells - Absorption" "Plasma membrane" "HPA040574: AB_2677026, HPA047804: AB_2680160" "unprognostic (1.16e-1)" "unprognostic (2.09e-4)" "unprognostic (2.40e-4)" "unprognostic (5.10e-2)" "unprognostic (3.88e-2)" "unprognostic (6.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (1.48e-8)" "unprognostic (2.85e-1)" "unprognostic (7.53e-3)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.6;Distal enterocytes: 151.2;Proximal enterocytes: 339.5;Proximal tubular cells: 107.9;Syncytiotrophoblasts: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cancer enhanced" "Detected in all" "prostate cancer: 42.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 50: Enterocytes - Absorption" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" SNX18 "SH3PX2, SH3PXD3B, SNAG1" ENSG00000178996 "Sorting nexin 18" Q96RF0 5 54517759-54546586 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0" "Cell type enhanced" "Detected in many" "monocytes: 201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037800 Approved Approved Cytosol NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA037800: AB_10672465" "unprognostic (2.22e-2)" "unprognostic (3.96e-3)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (4.12e-1)" "unprognostic (2.22e-1)" "unprognostic (9.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (9.13e-2)" "unprognostic (3.81e-3)" "prognostic favorable (1.58e-4)" "unprognostic (6.79e-3)" "unprognostic (7.96e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" SNX30 ATG24A ENSG00000148158 "Sorting nexin family member 30" Q5VWJ9 9 112750760-112881671 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 115.7;Oligodendrocytes: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019346 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 55: Non-specific - Unknown function" "Cluster 41: Alveolar cells - Lung function" "Nucleoplasm, Nucleoli, Cytosol" "HPA019346: AB_2286395" "unprognostic (1.67e-2)" "unprognostic (1.38e-1)" "unprognostic (1.08e-1)" "unprognostic (3.61e-1)" "unprognostic (3.61e-1)" "unprognostic (3.69e-1)" "unprognostic (8.05e-3)" "unprognostic (2.04e-3)" "unprognostic (4.48e-2)" "unprognostic (3.59e-3)" "unprognostic (3.39e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.01e-7)" "unprognostic (4.48e-3)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-2)" SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 203.0;Endometrial stromal cells: 98.0;Endothelial cells: 108.8;Leydig cells: 91.2;Peritubular cells: 103.5;Prostatic glandular cells: 131.5" "Cancer enhanced" "Detected in all" "prostate cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 177.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 177.8" "Cancer enhanced" "Detected in all" "Leukemia: 97.1" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favorable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favorable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" SOWAHB ANKRD56 ENSG00000186212 "Sosondowah ankyrin repeat domain family member B" A6NEL2 4 76894152-76898144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.2;Hepatocytes: 14.0;Intestinal goblet cells: 10.1;Paneth cells: 9.2;Proximal enterocytes: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036809, HPA036810" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Nucleoli fibrillar center" "HPA036809: AB_10672479, HPA036810: AB_2675327" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (3.06e-1)" "unprognostic (2.85e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.22e-15)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (3.73e-3)" SOX13 "ICA12, MGC117216, Sox-13" ENSG00000143842 "SRY-box transcription factor 13" Q9UN79 1 204073115-204127743 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051790, HPA054843" Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "HPA051790: AB_2681610, HPA054843: AB_2682622" "unprognostic (4.88e-3)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (4.74e-2)" "unprognostic (2.65e-1)" "unprognostic (3.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (2.75e-1)" "unprognostic (2.95e-1)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.48e-3)" "unprognostic (1.04e-1)" "unprognostic (8.20e-2)" "unprognostic (7.98e-2)" "unprognostic (1.92e-1)" SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 4 "Hofbauer cells: 490.5;Kupffer cells: 283.2;Langerhans cells: 617.7;Macrophages: 432.6;monocytes: 546.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Group enriched" "Detected in some" 14 "Leukemia: 124.1;lymphoma: 61.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 248.1;Inhibitory neurons: 341.8;Muller glia cells: 217.2;Oligodendrocyte precursor cells: 261.9;Oligodendrocytes: 862.0;Peritubular cells: 145.7" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 122.8;thyroid cancer: 125.9" "Kidney - Podocytes, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 387.5;Endometrial stromal cells: 81.6;Muller glia cells: 148.6" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in many" 8 "ovarian cancer: 145.2;Uterine cancer: 92.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077546 Uncertain "Secreted to blood" NA No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0;pituitary gland: 5.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 11.2;Excitatory neurons: 9.7;Horizontal cells: 7.0;Inhibitory neurons: 10.1" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 27: TE 441.T - Unknown function" "Cluster 55: Endocrine cells - Hormone signaling" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 816.2;Endothelial cells: 371.4;Fibroblasts: 221.9;Leydig cells: 411.8;Thymic epithelial cells: 318.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 9 "Club cells: 21.0;Early spermatids: 54.4;Endometrial ciliated cells: 26.6;Hepatocytes: 21.2;Late spermatids: 71.9;Respiratory ciliated cells: 18.7" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" SRGAP1 "ARHGAP13, KIAA1304" ENSG00000196935 "SLIT-ROBO Rho GTPase activating protein 1" Q7Z6B7 12 63844700-64162217 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 154.0;Early spermatids: 191.2;Microglial cells: 147.8;Oligodendrocyte precursor cells: 153.1;Oligodendrocytes: 128.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052416, HPA078079" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Kidney - Mixed function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Cytosol Centrosome "HPA052416: AB_2681824, HPA078079: " "unprognostic (3.05e-3)" "unprognostic (2.28e-1)" "unprognostic (1.58e-2)" "unprognostic (2.22e-3)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.45e-3)" "unprognostic (1.43e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (3.54e-3)" "unprognostic (8.56e-2)" "unprognostic (1.41e-3)" "unprognostic (8.16e-2)" "unprognostic (2.08e-1)" "unprognostic (8.31e-2)" "unprognostic (1.56e-2)" SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.2" "Cell type enhanced" "Detected in many" "Microglial cells: 176.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Podocytes, Skin - Keratinocyte (other)" HPA078079 Approved Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: Skin cancer - Membrane components" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Centrosome "HPA078079: " "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (7.65e-3)" "unprognostic (1.48e-6)" "unprognostic (2.40e-2)" "unprognostic (1.11e-1)" "unprognostic (7.18e-4)" "unprognostic (6.10e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (2.89e-1)" "unprognostic (3.71e-7)" "unprognostic (4.90e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" "unprognostic (7.66e-2)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Fibroblasts: 138.9;Leydig cells: 188.9;Peritubular cells: 269.9;Skeletal myocytes: 172.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Group enriched" "Detected in many" 5 "Endothelial cells: 127.8;Fibroblasts: 127.2;Hofbauer cells: 147.9;Kupffer cells: 242.8;Macrophages: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Cancer enriched" "Detected in single" 64 "Leukemia: 14.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" STAP1 "BRDG1, STAP-1" ENSG00000035720 "Signal transducing adaptor family member 1" Q9ULZ2 4 67558727-67607337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 51.0" "Cell type enhanced" "Detected in some" "B-cells: 68.2;dendritic cells: 22.6;Distal tubular cells: 28.0;granulocytes: 55.6;Plasma cells: 134.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 13.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 88.1;naive B-cell: 107.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Leukemia: 14.5;lymphoma: 55.0" "Colon - Mast cells, Kidney - Intercalated cells, Testis - Early spermatids" "Region enriched" "Detected in single" 5 "cerebellum: 2.3" "Low region specificity" "Detected in all" "HPA038529, HPA058018" Enhanced Supported "Nucleoplasm,Centriolar satellite,Mitochondria,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" "Nucleoplasm, Centriolar satellite, Mitochondria" Cytosol "HPA038529: AB_10673011, HPA058018: " "unprognostic (1.14e-4)" "unprognostic (1.49e-3)" "unprognostic (2.30e-2)" "unprognostic (2.17e-1)" "unprognostic (1.63e-3)" "unprognostic (6.30e-4)" "unprognostic (1.95e-3)" "unprognostic (6.95e-3)" "unprognostic (5.18e-2)" "unprognostic (6.38e-3)" "unprognostic (1.47e-1)" "unprognostic (8.43e-3)" "unprognostic (3.11e-2)" "unprognostic (1.49e-2)" "unprognostic (4.69e-2)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 65.7;Early spermatids: 320.6;Excitatory neurons: 84.7;Late spermatids: 77.7;NK-cells: 226.8;T-cells: 125.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cancer enhanced" "Detected in many" "Myeloma: 7.4" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 1: T-cells - Immune response" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 83.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 150.5;Club cells: 63.7;Ionocytes: 148.4;Prostatic glandular cells: 183.2;Thymic epithelial cells: 88.9" "Cancer enriched" "Detected in all" 6 "prostate cancer: 94.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 153.4" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA030985 Uncertain NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 5: Bronchus - Unknown function" "HPA030985: AB_2673686" "unprognostic (2.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.21e-3)" "unprognostic (9.20e-3)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" "unprognostic (6.74e-3)" "unprognostic (6.36e-2)" "unprognostic (6.45e-3)" "unprognostic (8.31e-3)" "unprognostic (3.79e-1)" "unprognostic (2.60e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-1)" "unprognostic (6.09e-2)" "unprognostic (1.38e-1)" STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 951.6;lymphoid tissue: 1343.2" "Cell type enhanced" "Detected in all" "Late spermatids: 2566.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 424.6" "Group enriched" "Detected in all" 5 "dendritic cells: 424.6;T-cells: 143.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 320000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 43: Non-specific - Cell proliferation" Cytosol "CAB010107: AB_628297, HPA068438: " "unprognostic (6.30e-2)" "unprognostic (2.40e-3)" "unprognostic (5.31e-2)" "unprognostic (7.94e-2)" "unprognostic (1.89e-1)" "unprognostic (5.02e-2)" "prognostic unfavorable (9.90e-7)" "unprognostic (9.45e-2)" "unprognostic (1.39e-2)" "unprognostic (1.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-3)" "unprognostic (1.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-2)" STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 437.6;Alveolar cells type 1: 397.5;Endothelial cells: 353.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Neutrophils, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.4;Inhibitory neurons: 87.7;Oligodendrocyte precursor cells: 97.2;Squamous epithelial cells: 79.5;Suprabasal keratinocytes: 50.0;Theca cells: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cancer enhanced" "Detected in many" "breast cancer: 16.5" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 34.5;retina: 56.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 132.3;Cone photoreceptor cells: 148.2;Excitatory neurons: 448.6;Rod photoreceptor cells: 147.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" SYNPO2 MYOPODIN ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 991.6;tongue: 493.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 195.8;Endometrial stromal cells: 136.1;Excitatory neurons: 147.5;Peritubular cells: 105.1;Sertoli cells: 116.1;Skeletal myocytes: 449.3;Smooth muscle cells: 256.9" "Group enriched" "Detected in all" 5 "prostate cancer: 25.7;stomach cancer: 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 43.0;Rhabdoid: 16.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Vesicles, Actin filaments" "CAB037231: AB_262098, HPA030665: AB_10696210, HPA049707: AB_2680857, HPA068563: AB_2686006" "unprognostic (1.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.50e-2)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (5.71e-4)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.91e-4)" SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;liver: 86.7;salivary gland: 57.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.8;Enteroendocrine cells: 49.8;Excitatory neurons: 80.9;Hepatocytes: 60.8;Horizontal cells: 78.2;Prostatic glandular cells: 107.1;Syncytiotrophoblasts: 77.8" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Region enhanced" "Detected in many" "cerebral cortex: 78.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 38.0" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;retina: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 47.1;Late spermatids: 26.2;Oligodendrocyte precursor cells: 52.9;Oligodendrocytes: 131.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.2" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 159.5;NK-cells: 150.6;Squamous epithelial cells: 181.7;Suprabasal keratinocytes: 151.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 62.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Skin - Keratinocyte (other), Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 102.9;Proximal enterocytes: 86.1;Proximal tubular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 81.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cancer enhanced" "Detected in some" "Brain cancer: 2.3;ovarian cancer: 1.3" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 32: Neurons - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 235.3;dendritic cells: 89.0;Langerhans cells: 70.5;Macrophages: 85.3;monocytes: 75.4;NK-cells: 128.5;Plasma cells: 202.8;T-cells: 211.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 9.8;lymphoma: 16.6;Myeloma: 7.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enhanced" "Detected in some" "Adipocytes: 24.0;Endothelial cells: 17.6;Erythroid cells: 82.7;granulocytes: 30.9;Late spermatids: 18.5;Microglial cells: 28.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 27.9" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 297.4;dendritic cells: 852.6;monocytes: 316.2;NK-cells: 154.9;Schwann cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.0" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 56: Neurons - Neuronal signaling" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 40.4;intestine: 25.6;lymphoid tissue: 58.6" "Cell type enhanced" "Detected in many" "B-cells: 110.1;monocytes: 54.0;NK-cells: 192.7;T-cells: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 33.5;lymphoma: 27.3" "Adipose subcutaneous - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear bodies" "HPA069743: AB_2686186" "prognostic favorable (3.83e-4)" "prognostic favorable (4.20e-4)" "unprognostic (9.23e-2)" "unprognostic (3.84e-2)" "unprognostic (1.28e-3)" "prognostic favorable (1.86e-5)" "unprognostic (6.22e-3)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (3.55e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (7.18e-2)" "unprognostic (3.81e-2)" TBC1D15 "DKFZp761D0223, FLJ12085" ENSG00000121749 "TBC1 domain family member 15" Q8TC07 12 71839707-71927248 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 207.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013388, HPA015592" Supported Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 14: Endometrium - Transcription regulation" "Mitochondria, Cytosol" "HPA013388: AB_2199233, HPA015592: AB_1857789" "unprognostic (3.87e-2)" "prognostic favorable (7.06e-4)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (4.63e-2)" "unprognostic (6.13e-3)" "unprognostic (2.96e-2)" "unprognostic (3.10e-1)" "unprognostic (2.61e-1)" "unprognostic (1.02e-2)" "unprognostic (4.07e-2)" "unprognostic (2.18e-1)" "prognostic favorable (5.34e-4)" "unprognostic (5.73e-2)" "unprognostic (4.34e-2)" "unprognostic (2.31e-1)" "unprognostic (2.78e-1)" TBC1D5 KIAA0210 ENSG00000131374 "TBC1 domain family member 5" Q92609 3 17157162-18444817 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 219.5;Excitatory neurons: 328.3;Inhibitory neurons: 342.8;Microglial cells: 315.6;Oligodendrocyte precursor cells: 327.3;Oligodendrocytes: 533.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035125, HPA035126" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 5: Non-specific - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Vesicles "Golgi apparatus" "HPA035125: AB_2674479, HPA035126: AB_10670696" "unprognostic (1.87e-1)" "unprognostic (3.57e-1)" "unprognostic (2.86e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (4.30e-3)" "unprognostic (3.07e-2)" "unprognostic (3.31e-1)" "unprognostic (3.56e-2)" "unprognostic (6.27e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (1.75e-7)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (5.72e-2)" "unprognostic (7.07e-2)" TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.3" "Cell type enriched" "Detected in some" 4 "Microglial cells: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006807 Supported Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "HPA006807: " "unprognostic (8.04e-2)" "unprognostic (7.06e-3)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (2.57e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-14)" "unprognostic (4.81e-5)" "unprognostic (1.86e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Asthma, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Group enriched" "Detected in some" 10 "NK-cells: 128.0;T-cells: 42.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Group enriched" "Detected in some" 13 "Leukemia: 1.8;lymphoma: 4.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 12.9;Hepatocytes: 10.2;Suprabasal keratinocytes: 7.7;Syncytiotrophoblasts: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Fibroblast_1" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 33: Skin cancer - Membrane components" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" TCEAL6 WEX2 ENSG00000204071 "Transcription elongation factor A like 6" Q6IPX3 X 102140476-102142970 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 73.4;testis: 26.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.8;Horizontal cells: 22.4;Inhibitory neurons: 10.2;Pancreatic endocrine cells: 10.3;Sertoli cells: 55.3;Thymic epithelial cells: 9.6" "Cancer enriched" "Detected in single" 9 "glioma: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Podocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "HPA045564, HPA058982" Supported Uncertain Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (5.43e-2)" "unprognostic (6.54e-2)" "unprognostic (1.87e-3)" "unprognostic (6.69e-3)" "unprognostic (1.39e-1)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (3.89e-2)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.33e-2)" "unprognostic (1.18e-1)" TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 195.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 62: Granulocytes - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 799.4;dendritic cells: 1077.5;Inhibitory neurons: 1149.1;Oligodendrocyte precursor cells: 689.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cancer enhanced" "Detected in many" "Neuroblastoma: 59.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 48.4;Early spermatids: 68.0;Exocrine glandular cells: 42.0;Late spermatids: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in some" 6 "Adipocytes: 67.9;Endothelial cells: 76.7;Microglial cells: 37.4;Oligodendrocyte precursor cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Rhabdoid: 16.9;testis cancer: 18.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" TESPA1 "ITPRID3, KIAA0748" ENSG00000135426 "Thymocyte expressed, positive selection associated 1" A2RU30 12 54948015-54984762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.3;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 32.3;Excitatory neurons: 200.1;granulocytes: 88.4;T-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Leukemia: 42.7;lymphoma: 24.5" "Adipose visceral - T-cells, Colon - Mast cells, Kidney - T-cells, Skeletal muscle - Fibroblasts, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058823, HPA079222" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA058823: AB_2683828, HPA079222: " "unprognostic (1.98e-5)" "unprognostic (3.70e-4)" "unprognostic (3.87e-4)" "unprognostic (1.13e-3)" "unprognostic (3.20e-2)" "unprognostic (4.55e-4)" "unprognostic (2.29e-3)" "unprognostic (5.34e-4)" "unprognostic (3.83e-4)" "unprognostic (1.35e-2)" "unprognostic (3.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.50e-2)" "unprognostic (4.11e-1)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 93.0;Horizontal cells: 337.7;Melanocytes: 182.9" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bone cancer: 24.1;breast cancer: 21.6;Neuroblastoma: 46.1" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 394.6;Alveolar cells type 1: 203.2;Endothelial cells: 391.4;Fibroblasts: 211.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "pituitary gland: 106.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.9;Distal tubular cells: 6.2;Excitatory neurons: 7.2;Plasma cells: 6.6;Proximal tubular cells: 7.7;Sertoli cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 53: Non-specific - mRNA processing" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 46.3;Microglial cells: 14.6;Serous glandular cells: 10.9;T-cells: 66.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 19 "Leukemia: 3.6;lymphoma: 3.1;Myeloma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 35.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.2;Hepatocytes: 12.1;Late spermatids: 2.9;Proximal tubular cells: 9.1" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 1.3;liver cancer: 3.9;lung cancer: 1.4;lymphoma: 3.5;testis cancer: 2.3" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1070000 "Cluster 15: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 59: Fibroblasts - Metabolism" "Cluster 9: Neurons - Nervous system development" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 8 "NK-cells: 60.8;T-cells: 79.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Group enriched" "Detected in some" 7 "lymphoma: 4.5;Myeloma: 1.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 445.3;Late spermatids: 482.9;Leydig cells: 362.3;Melanocytes: 360.5;Peritubular cells: 748.7;Theca cells: 461.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 12: Non-specific - Chromatin organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 110.2" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.9;lymphoid tissue: 51.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 91.8;Langerhans cells: 49.1;Macrophages: 109.0;monocytes: 207.7;Mucus glandular cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 199.6;intermediate monocyte: 178.9;myeloid DC: 121.3;neutrophil: 457.8;non-classical monocyte: 121.5" "Group enriched" "Detected in all" 49 "dendritic cells: 121.3;granulocytes: 457.8;monocytes: 199.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 14.0;Leukemia: 10.5" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 49.3;Endothelial cells: 41.5;Hofbauer cells: 73.7;Kupffer cells: 129.6;Macrophages: 89.3;monocytes: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cancer enhanced" "Detected in many" "Brain cancer: 11.8" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 52.0;granulocytes: 30.8;Hofbauer cells: 31.4;Langerhans cells: 43.5;monocytes: 38.7;NK-cells: 66.1;T-cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 67.0;lymphoma: 48.3;Myeloma: 71.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 230.3;Glandular and luminal cells: 552.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 79.7;Bipolar cells: 79.7;Ductal cells: 85.3;Horizontal cells: 156.4;Muller glia cells: 164.7;Rod photoreceptor cells: 171.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 65: Breast cancer - Unknown function" "Cluster 68: Muller glia cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 139.5;Early spermatids: 115.6;Late spermatids: 92.7;Proximal tubular cells: 71.0;Syncytiotrophoblasts: 129.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 59: Fibroblasts - Metabolism" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA019015: AB_2204758" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-3)" "unprognostic (4.09e-3)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-2)" "unprognostic (5.80e-2)" "unprognostic (2.64e-2)" "unprognostic (2.54e-3)" "unprognostic (7.16e-2)" "unprognostic (8.27e-3)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (6.87e-3)" TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1038.0;Paneth cells: 738.1;Proximal enterocytes: 1334.3;Proximal tubular cells: 883.1" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 34.0;Gastric cancer: 34.6;liver cancer: 13.0;lung cancer: 16.6;Neuroblastoma: 10.8;pancreatic cancer: 17.6;thyroid cancer: 16.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Excitatory neurons: 107.3;Horizontal cells: 32.7;Inhibitory neurons: 106.8;Oligodendrocyte precursor cells: 32.3" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 18.2;testis cancer: 23.7" "Colon - Enteric glia cells, Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Intestine - Brush border" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 89.3" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052596, HPA054732" Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 79: Retina - Phototransduction" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "HPA052596: AB_2681879, HPA054732: AB_2682587" "unprognostic (1.70e-1)" "unprognostic (7.10e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (1.73e-1)" "unprognostic (4.06e-1)" "unprognostic (8.30e-6)" "unprognostic (4.15e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.96e-6)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 484.4;Club cells: 528.6;Early spermatids: 253.0;Ionocytes: 620.0;Suprabasal keratinocytes: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 59: Fibroblasts - Metabolism" "Cluster 5: Bronchus - Unknown function" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.8;Kupffer cells: 31.5;Langerhans cells: 34.5;Macrophages: 23.2;monocytes: 20.0;NK-cells: 66.7;Schwann cells: 21.6;T-cells: 34.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7;Leukemia: 8.4" "Colon - Enteric glia cells, Kidney - T-cells, Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" TMEM88B ENSG00000205116 "Transmembrane protein 88B" A6NKF7 1 1426128-1427787 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "brain: 437.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065743 Enhanced NA NA "Cluster 70: Brain - Nervous system development" "Cluster 44: Myeloma - Humoral immune response" "HPA065743: AB_2685552" "unprognostic (3.17e-2)" "unprognostic (1.42e-2)" "unprognostic (1.63e-4)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "unprognostic (2.67e-1)" "unprognostic (2.91e-2)" "unprognostic (5.30e-5)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (3.53e-2)" "unprognostic (7.19e-2)" "unprognostic (1.45e-1)" "unprognostic (7.95e-2)" TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6;choroid plexus: 10.5;pituitary gland: 9.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Horizontal cells: 3.2;Skeletal myocytes: 3.0;Spermatocytes: 3.2;Spermatogonia: 3.1" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Breast - T-cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 9: Neurons - Nervous system development" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.6;Gastric mucus-secreting cells: 172.9;Paneth cells: 149.4;Prostatic glandular cells: 377.5;Proximal enterocytes: 170.9" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 271.4" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 50: Enterocytes - Absorption" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.6;choroid plexus: 20.8" "Cell type enhanced" "Detected in some" "Astrocytes: 25.6;Mucus glandular cells: 15.4;Oligodendrocytes: 14.6;Schwann cells: 17.5;Serous glandular cells: 11.4" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 5.3" "Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 56: Neurons - Neuronal signaling" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 103.5;granulocytes: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 19: Macrophages - Innate immune response" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.2" "Cell type enhanced" "Detected in many" "dendritic cells: 48.8;Inhibitory neurons: 75.1;Late spermatids: 22.8;Oligodendrocyte precursor cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bone cancer: 49.5" "Breast - Endothelial cells, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "HPA049900: AB_2680942, HPA058396: AB_2683704" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (8.97e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (7.53e-3)" "unprognostic (6.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (7.45e-8)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (7.60e-2)" "unprognostic (3.12e-1)" TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;retina: 17.6;stomach 1: 20.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 59.7;Inhibitory neurons: 135.5;Muller glia cells: 138.3;Oligodendrocyte precursor cells: 49.6;Oligodendrocytes: 70.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Breast - Breast glandular cells, Kidney - Intercalated cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 41: Non-specific - Cilium assembly" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA040240: , HPA040376: AB_10795522" "unprognostic (1.14e-2)" "unprognostic (9.75e-3)" "unprognostic (9.08e-3)" "unprognostic (3.32e-2)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (4.74e-3)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (2.59e-1)" "unprognostic (4.60e-3)" "prognostic favorable (3.08e-12)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.95e-4)" TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10621.0;skeletal muscle: 12678.0;tongue: 5183.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 15062.8;Exocrine glandular cells: 2704.5;Extravillous trophoblasts: 3641.6;Pancreatic endocrine cells: 3058.9;Skeletal myocytes: 5271.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.7" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.7;monocytes: 19.2" "Cancer enhanced" "Detected in all" "testis cancer: 3810.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 77: Cardiomyocytes - Muscle contraction" "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155077 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 76.4;liver: 68.8;thyroid gland: 76.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 129.1;Proximal tubular cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA 39000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "HPA019851: AB_1858213, HPA062364: " "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favorable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 11 "T-cells: 118.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Cancer enhanced" "Detected in some" "Leukemia: 10.2;lymphoma: 2.5;Myeloma: 2.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 24.1" "Cell type enriched" "Detected in single" 15 "T-cells: 12.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.1;memory CD4 T-cell: 143.4;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.2;naive CD8 T-cell: 80.1;T-reg: 190.6" "Lineage enriched" "Detected in many" 184 "T-cells: 190.6" "Group enriched" "Detected in some" 7 "Leukemia: 1.1;lymphoma: 2.8;Rhabdoid: 1.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - Podocytes, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (5.88e-3)" "unprognostic (9.98e-4)" "unprognostic (2.31e-2)" "unprognostic (2.23e-2)" "unprognostic (9.88e-5)" "unprognostic (1.94e-3)" "unprognostic (7.22e-3)" "unprognostic (9.30e-3)" "unprognostic (2.82e-3)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (7.57e-5)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.02e-1)" TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 17 "NK-cells: 443.4;T-cells: 435.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 98.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 150.2;NK-cells: 264.0;T-cells: 515.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cancer enriched" "Detected in single" 15 "Leukemia: 12.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 30.1" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Cancer enriched" "Detected in single" 46 "Leukemia: 13.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 4 "NK-cells: 84.0;T-cells: 110.9" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Group enriched" "Detected in some" 23 "Leukemia: 42.6;prostate cancer: 13.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - Prostate glandular cells, Skin - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" TRGV10 "TCRGV10, V3P" ENSG00000211694 "T cell receptor gamma variable 10 (non-functional)" 7 38299811-38300322 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.9" "Cell type enriched" "Detected in some" 4 "T-cells: 27.0" "Cancer enriched" "Detected in many" 8 "prostate cancer: 7.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 196.5" "Lineage enriched" "Detected in many" 8 "T-cells: 196.5" "Group enriched" "Detected in some" 6 "Leukemia: 5.2;prostate cancer: 1.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.59e-2)" "unprognostic (4.53e-3)" "unprognostic (5.13e-2)" "unprognostic (2.94e-3)" "unprognostic (1.54e-2)" "unprognostic (1.22e-4)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.53e-2)" "unprognostic (1.94e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-4)" "unprognostic (2.68e-1)" "unprognostic (9.00e-2)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" TRIL KIAA0644 ENSG00000255690 "TLR4 interactor with leucine rich repeats" Q7L0X0 7 28953358-28958330 "Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 68.0" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Fibroblasts: 15.2;Muller glia cells: 17.7;Oligodendrocyte precursor cells: 12.5" "Cancer enhanced" "Detected in many" "glioma: 20.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.8;Neuroblastoma: 5.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 65: Breast cancer - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (1.26e-3)" "unprognostic (3.29e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (4.27e-3)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.07e-2)" TRIM14 KIAA0129 ENSG00000106785 "Tripartite motif containing 14" Q14142 9 98069275-98119222 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053217 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 69: Macrophages - Innate immune response" "HPA053217: AB_2682082" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-1)" "unprognostic (9.80e-2)" "unprognostic (9.00e-2)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.55e-3)" "unprognostic (4.57e-2)" TRPM2 "EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7" ENSG00000142185 "Transient receptor potential cation channel subfamily M member 2" O94759 21 44350163-44443081 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sodium transport, Transport" "Calcium channel, Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.2;brain: 26.4;lymphoid tissue: 18.4" "Cell type enhanced" "Detected in many" "dendritic cells: 25.6;Excitatory neurons: 51.9;Hofbauer cells: 17.2;Inhibitory neurons: 44.2;Macrophages: 19.3;Microglial cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 7.8;plasmacytoid DC: 15.5" "Group enriched" "Detected in many" 6 "dendritic cells: 15.5;monocytes: 7.8" "Cancer enhanced" "Detected in many" "Leukemia: 43.8" "Adipose visceral - Macrophages, Kidney - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035260 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA035260: AB_2674540" "unprognostic (3.61e-2)" "unprognostic (2.18e-1)" "unprognostic (7.55e-2)" "prognostic favorable (9.28e-4)" "unprognostic (6.49e-2)" "unprognostic (4.54e-2)" "unprognostic (5.17e-2)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (2.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.40e-1)" "unprognostic (3.31e-2)" "unprognostic (8.88e-3)" "prognostic favorable (7.59e-4)" TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.6;intestine: 16.6" "Group enriched" "Detected in some" 6 "Distal enterocytes: 66.3;Glandular and luminal cells: 28.2;Microglial cells: 38.3;Oligodendrocytes: 76.5;Proximal enterocytes: 19.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.1;neutrophil: 7.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 23.1" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.8" "Kidney - Intercalated cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 50: Enterocytes - Absorption" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" TSHZ2 "C20orf17, OVC10-2, TSH2, ZABC2, ZNF218" ENSG00000182463 "Teashirt zinc finger homeobox 2" Q9NRE2 20 52972358-53495330 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 383.2;Leydig cells: 465.5;Mucus glandular cells: 263.2;Peritubular cells: 790.5;Theca cells: 306.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0;T-reg: 2.4" "Lineage enriched" "Detected in single" 4 "T-cells: 3.0" "Cancer enhanced" "Detected in many" "cervical cancer: 9.2" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA038123 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 17: Granulosa cells - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA038123: AB_10670657" "unprognostic (9.24e-3)" "unprognostic (1.58e-1)" "unprognostic (9.35e-2)" "unprognostic (1.13e-1)" "unprognostic (1.21e-4)" "unprognostic (3.30e-1)" "unprognostic (4.30e-1)" "unprognostic (1.28e-1)" "unprognostic (2.16e-1)" "unprognostic (3.23e-2)" "unprognostic (3.33e-1)" "unprognostic (3.14e-2)" "unprognostic (9.88e-8)" "unprognostic (6.26e-2)" "unprognostic (3.81e-2)" "unprognostic (3.37e-7)" "unprognostic (2.97e-3)" TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Cell type enhanced" "Detected in many" "Adipocytes: 70.9;Cardiomyocytes: 19.7;Early spermatids: 20.4;Endothelial cells: 58.5;Proximal tubular cells: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Neuroblastoma: 28.8;testis cancer: 99.8" "Breast - Endothelial cells, Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" TTC29 NYD-SP14 ENSG00000137473 "Tetratricopeptide repeat domain 29" Q8NA56 4 146706617-146945882 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "fallopian tube: 20.0;testis: 71.8" "Group enriched" "Detected in some" 4 "Early spermatids: 733.6;Late spermatids: 479.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037006, HPA061473" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "HPA037006: AB_10670379, HPA061473: AB_2684534" "unprognostic (1.28e-3)" "unprognostic (1.52e-2)" "unprognostic (8.21e-2)" "unprognostic (1.70e-1)" "unprognostic (6.70e-2)" "unprognostic (1.35e-1)" "unprognostic (6.94e-3)" "unprognostic (1.32e-1)" "unprognostic (5.67e-4)" "unprognostic (9.81e-4)" "unprognostic (7.30e-2)" "unprognostic (6.88e-4)" TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 387.9;choroid plexus: 154.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 233.2;Horizontal cells: 151.9;Melanocytes: 142.8;Muller glia cells: 832.0;Schwann cells: 143.8" "Cancer enriched" "Detected in many" 9 "glioma: 216.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 444.6" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: DU4475 - Unknown function" "Cluster 9: Neurons - Nervous system development" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (5.92e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.81e-2)" "unprognostic (3.26e-2)" "unprognostic (9.03e-3)" "unprognostic (8.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.78e-3)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "unprognostic (6.24e-3)" "unprognostic (6.04e-2)" "unprognostic (3.58e-4)" "unprognostic (2.30e-3)" TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 277.7;Extravillous trophoblasts: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 54: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" TXN TRX ENSG00000136810 Thioredoxin P10599 9 110243810-110256507 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transcription, Transcription regulation, Transport" Activator Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1058.8" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3571.8;Proximal tubular cells: 3392.0;Suprabasal keratinocytes: 4110.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1642.2;granulocytes: 1355.4" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008678, HPA047478, HPA055752" Enhanced Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 23: Langerhans cells - Immune response" "Nucleoplasm, Cytosol" "CAB008678: AB_1623676, HPA047478: AB_2680063, HPA055752: AB_2682907" "unprognostic (2.12e-2)" "unprognostic (1.27e-1)" "unprognostic (9.77e-2)" "prognostic favorable (3.40e-6)" "unprognostic (1.80e-2)" "unprognostic (2.13e-2)" "unprognostic (5.52e-3)" "unprognostic (1.37e-2)" "unprognostic (1.75e-1)" "unprognostic (3.36e-2)" "unprognostic (5.93e-3)" "unprognostic (1.66e-1)" "unprognostic (4.96e-3)" "unprognostic (7.80e-2)" "unprognostic (8.55e-2)" "unprognostic (2.99e-2)" "unprognostic (8.51e-2)" TXNDC17 "MGC14353, TRP14, TXNL5" ENSG00000129235 "Thioredoxin domain containing 17" Q9BRA2 17 6640985-6644541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 182.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 742.3;Proximal tubular cells: 768.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022931 Approved NA NA 820000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "HPA022931: AB_1858479" "unprognostic (8.94e-2)" "unprognostic (6.03e-2)" "unprognostic (5.33e-2)" "unprognostic (2.97e-2)" "unprognostic (5.02e-2)" "unprognostic (5.06e-2)" "unprognostic (7.65e-3)" "unprognostic (3.88e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-3)" "unprognostic (1.15e-2)" "unprognostic (9.97e-2)" "prognostic unfavorable (1.15e-5)" "unprognostic (8.86e-2)" "unprognostic (2.27e-1)" "unprognostic (3.09e-2)" "unprognostic (9.01e-2)" U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 60.5;Plasma cells: 36.3;Squamous epithelial cells: 57.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 61: Non-specific - Transcription" Nucleoplasm "HPA044833: AB_10960990, HPA052083: AB_2681720" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enriched" "Detected in some" 5 "T-cells: 21.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 57 "Leukemia: 8.9;lymphoma: 2.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.7;tongue: 65.3" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" UFM1 "bA131P10.1, C13orf20" ENSG00000120686 "Ubiquitin fold modifier 1" P61960 13 38349849-38363619 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039758 Approved NA NA 240000 "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 13: Non-specific - Nuclear processes" "Cluster 40: Plasma cells - Humoral immune response" "HPA039758: AB_10697555" "unprognostic (8.08e-2)" "unprognostic (3.29e-2)" "unprognostic (1.49e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.33e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (9.67e-2)" "unprognostic (1.68e-1)" "unprognostic (3.92e-2)" "unprognostic (1.45e-1)" "unprognostic (8.11e-2)" "unprognostic (7.03e-2)" "unprognostic (4.90e-3)" "unprognostic (1.12e-2)" "unprognostic (3.99e-1)" "unprognostic (8.23e-2)" "unprognostic (1.90e-1)" UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 22.0;intestine: 79.5;stomach 1: 32.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Distal enterocytes: 1.6;Gastric mucus-secreting cells: 4.8;Intestinal goblet cells: 1.2;Paneth cells: 1.4;Proximal enterocytes: 3.4;Squamous epithelial cells: 4.5" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 79.6;Gallbladder cancer: 128.2;pancreatic cancer: 73.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.6;Early spermatids: 25.0;Gastric mucus-secreting cells: 14.3;Late spermatids: 35.9;Squamous epithelial cells: 16.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 254.4" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844552 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 132.5;Hofbauer cells: 56.2;NK-cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1500000 "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol Vesicles "HPA067117: AB_2685784, HPA073525: AB_2686615" "unprognostic (6.79e-3)" "unprognostic (4.36e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.93e-1)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (5.28e-12)" "unprognostic (3.27e-2)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (8.59e-2)" UNC5CL "MGC34763, ZUD" ENSG00000124602 "Unc-5 family C-terminal like" Q8IV45 6 41026895-41039221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 37.1;kidney: 58.6;liver: 52.8;pancreas: 36.2;stomach 1: 23.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.6;Ductal cells: 33.0;Exocrine glandular cells: 68.3;Gastric mucus-secreting cells: 38.2;Hepatocytes: 24.6;Proximal enterocytes: 33.0;Proximal tubular cells: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA015725 Enhanced Approved Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Centrosome "HPA015725: AB_2669283" "unprognostic (1.10e-2)" "unprognostic (3.59e-2)" "unprognostic (1.60e-1)" "unprognostic (2.57e-1)" "unprognostic (7.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (8.55e-3)" "unprognostic (3.58e-1)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" "unprognostic (9.30e-2)" "unprognostic (2.35e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-1)" "unprognostic (5.60e-6)" USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Adipocytes: 37.9;Endothelial cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: BEWO - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179653032-179804366 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 149.2;tongue: 108.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 206.7;Inhibitory neurons: 51.0;Skeletal myocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 15.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: Non-specific - Mitochondria" "Cluster 77: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.06e-4)" UTP4 "CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292" ENSG00000141076 "UTP4 small subunit processome component" Q969X6 16 69131291-69231130 "Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041139, HPA043542" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 36: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" "Nucleoli fibrillar center" "HPA041139: AB_10961278, HPA043542: AB_2678542" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.89e-2)" "unprognostic (6.16e-3)" "prognostic unfavorable (9.05e-5)" "prognostic unfavorable (8.18e-7)" "unprognostic (1.31e-1)" "unprognostic (4.76e-2)" "prognostic favorable (2.88e-5)" "unprognostic (2.12e-2)" "unprognostic (4.45e-2)" "unprognostic (2.32e-3)" "unprognostic (9.57e-3)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.20e-2)" VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 503.4;Endothelial cells: 357.5;Melanocytes: 329.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 89.2;intestine: 136.3;liver: 218.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Ductal cells: 241.7;Exocrine glandular cells: 49.3;Glandular and luminal cells: 48.2;Hepatocytes: 68.3;monocytes: 95.2;Proximal enterocytes: 52.8" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.7;pancreatic cancer: 10.7" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" NA NA 980000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 264.4;Exocrine glandular cells: 158.2;Schwann cells: 374.0;Syncytiotrophoblasts: 261.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 112.1" "Kidney - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in all" "monocytes: 336.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" WEE2 "FLJ16107, WEE1B" ENSG00000214102 "WEE2 oocyte meiosis inhibiting kinase" P0C1S8 7 141708353-141731271 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Proximal tubular cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA027418, HPA054280" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 293.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells, Lung - Alveolar cells type 1, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 45: Non-specific - Cell proliferation" "Cluster 12: Non-specific - Chromatin organization" Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enhanced" "Detected in some" "Distal tubular cells: 174.1;Intestinal goblet cells: 75.0;Prostatic glandular cells: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.2;Extravillous trophoblasts: 26.7;Fibroblasts: 4.6;Inhibitory neurons: 4.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 17.5" "Kidney - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA055048 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA055048: AB_2682683" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.4" "Cell type enhanced" "Detected in some" "Adipocytes: 33.9;Fibroblasts: 22.1;Skeletal myocytes: 7.9;Theca cells: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 25.9" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050101 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "HPA050101: AB_2681015" "prognostic favorable (5.97e-4)" "unprognostic (9.27e-2)" "unprognostic (2.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (2.88e-2)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (3.16e-3)" "unprognostic (1.09e-3)" WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 3.5;prostate cancer: 1.9" "Kidney - Podocytes, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endothelial cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Skin cancer - Membrane components" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 14 "NK-cells: 529.3;T-cells: 240.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cancer enriched" "Detected in some" 7 "Sarcoma: 7.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: TE 441.T - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in some" 8 "NK-cells: 143.0;T-cells: 100.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 5 "Leukemia: 39.9;lymphoma: 13.5;Rhabdoid: 13.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 36.8;Inhibitory neurons: 38.5;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049584 Approved Approved Vesicles,Microtubules NA NA "Cluster 30: Non-specific - Translation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 48: Non-specific - RNA binding" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Vesicles, Microtubules" "HPA049584: AB_2680825" "unprognostic (9.55e-3)" "unprognostic (1.03e-1)" "unprognostic (4.40e-1)" "unprognostic (1.56e-1)" "unprognostic (7.29e-3)" "unprognostic (9.71e-2)" "unprognostic (1.64e-3)" "unprognostic (9.72e-2)" "unprognostic (2.98e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.44e-2)" "unprognostic (1.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.51e-5)" "unprognostic (5.34e-2)" ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 206.2;Endometrial stromal cells: 280.9;Excitatory neurons: 272.2;Inhibitory neurons: 255.3;Microglial cells: 467.0;Oligodendrocyte precursor cells: 927.6" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" ZFAND2A AIRAP ENSG00000178381 "Zinc finger AN1-type containing 2A" Q8N6M9 7 1152071-1160759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 180.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019469 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 63: Non-specific - Unknown function" "Cluster 50: Enterocytes - Absorption" "HPA019469: AB_1859009" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (3.08e-2)" "unprognostic (1.03e-2)" "unprognostic (7.12e-2)" "unprognostic (1.10e-2)" "unprognostic (2.10e-3)" "unprognostic (7.52e-2)" "unprognostic (8.78e-2)" "unprognostic (6.48e-2)" "prognostic unfavorable (5.47e-7)" "unprognostic (5.44e-3)" "unprognostic (7.60e-2)" "unprognostic (6.46e-2)" "unprognostic (2.59e-2)" ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 347.3;Bipolar cells: 81.2;Oligodendrocyte precursor cells: 224.3;Oligodendrocytes: 210.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" ZFP92 ZNF897 ENSG00000189420 "ZFP92 zinc finger protein" A6NM28 X 153418322-153426481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 3.0;Endometrial stromal cells: 2.9;Peritubular cells: 4.1;Sertoli cells: 8.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Fibroblasts" "Region enhanced" "Detected in many" "hypothalamus: 8.8" "Low region specificity" "Detected in all" HPA003030 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "HPA003030: AB_2666758" "unprognostic (6.94e-2)" "unprognostic (2.54e-2)" "unprognostic (7.85e-2)" "unprognostic (2.57e-4)" "unprognostic (1.01e-2)" "unprognostic (3.84e-2)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.62e-2)" "unprognostic (6.51e-3)" "unprognostic (6.71e-2)" "unprognostic (1.84e-1)" "unprognostic (8.49e-4)" "unprognostic (1.81e-1)" "unprognostic (2.71e-2)" "unprognostic (6.66e-3)" ZNF222 ENSG00000159885 "Zinc finger protein 222" Q9UK12 19 44025342-44033110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 10 "Early spermatids: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids" HPA004086 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies" "HPA004086: AB_2273259" "unprognostic (1.91e-3)" "unprognostic (3.41e-2)" "unprognostic (8.08e-2)" "unprognostic (1.02e-1)" "unprognostic (3.81e-2)" "unprognostic (7.45e-2)" "unprognostic (1.75e-3)" "unprognostic (6.75e-2)" "unprognostic (1.58e-2)" "unprognostic (7.58e-2)" "prognostic favorable (5.56e-7)" "unprognostic (2.19e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-1)" "unprognostic (8.42e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-3)" ZNF292 "bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16" ENSG00000188994 "Zinc finger protein 292" O60281 6 87152833-87265943 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032154, HPA050618" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Nuclear membrane" "HPA032154: AB_10601930, HPA050618: AB_2681190" "unprognostic (6.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (2.08e-3)" "unprognostic (2.28e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" "unprognostic (8.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.06e-2)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.02e-1)" "unprognostic (7.36e-2)" ZNF419 "ZAPHIR, ZNF419A" ENSG00000105136 "Zinc finger protein 419" Q96HQ0 19 57487711-57496098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "HPA003152, HPA003274" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA003152: AB_1080716, HPA003274: AB_1080714" "unprognostic (3.50e-2)" "unprognostic (1.40e-5)" "unprognostic (1.12e-1)" "unprognostic (2.63e-2)" "unprognostic (2.55e-2)" "unprognostic (8.26e-2)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (3.18e-1)" "unprognostic (1.33e-1)" "unprognostic (8.55e-5)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.53e-5)" ZNF432 KIAA0798 ENSG00000256087 "Zinc finger protein 432" O94892 19 52031378-52095738 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Prostate glandular cells" "HPA052082, HPA060274, HPA065606" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 4: Non-specific - Transcription" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "HPA052082: AB_2681719, HPA060274: AB_2684238, HPA065606: AB_2685518" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (1.92e-1)" "unprognostic (7.04e-3)" "unprognostic (1.08e-2)" "unprognostic (2.41e-3)" "unprognostic (3.19e-2)" "unprognostic (2.56e-1)" "unprognostic (6.92e-2)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (5.49e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "prognostic favorable (4.11e-5)" ZNF578 FLJ31384 ENSG00000258405 "Zinc finger protein 578" Q96N58 19 52453553-52516882 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.3" "Cell type enhanced" "Detected in many" "Early spermatids: 49.3;Late spermatids: 38.6" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 5.5" "Kidney - Endothelial cells, Testis - Early spermatids" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "unprognostic (6.57e-3)" "unprognostic (1.43e-2)" "unprognostic (1.56e-2)" "unprognostic (3.77e-2)" "unprognostic (1.60e-3)" "unprognostic (2.96e-3)" "unprognostic (5.42e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-2)" "unprognostic (8.14e-2)" "unprognostic (9.57e-3)" "unprognostic (7.61e-2)" "unprognostic (1.81e-1)" "unprognostic (2.64e-1)" "unprognostic (1.82e-1)" "unprognostic (3.96e-2)" "unprognostic (2.42e-1)" ZNF597 "FLJ33071, HIT-4" ENSG00000167981 "Zinc finger protein 597" Q96LX8 16 3432414-3443504 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 8.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA001556 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: Non-specific - Transcription" "Cluster 11: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "HPA001556: AB_1080740" "unprognostic (1.98e-1)" "unprognostic (8.07e-2)" "unprognostic (1.03e-1)" "unprognostic (9.15e-3)" "unprognostic (2.88e-1)" "unprognostic (6.16e-2)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (3.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.34e-1)" "unprognostic (8.75e-3)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (4.58e-1)" "unprognostic (2.89e-1)" "unprognostic (5.99e-3)" ZNF792 FLJ38451 ENSG00000180884 "Zinc finger protein 792" Q3KQV3 19 34956354-34964229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 6.9;Endothelial cells: 8.2;Skeletal myocytes: 4.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in many" "HPA035157, HPA035158" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Nuclear bodies" "HPA035157: AB_2674497, HPA035158: AB_10603010" "unprognostic (1.31e-1)" "unprognostic (7.31e-2)" "prognostic favorable (2.72e-4)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (7.91e-2)" "unprognostic (2.41e-5)" "unprognostic (2.49e-2)" "unprognostic (4.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.88e-1)" "unprognostic (2.48e-1)" "unprognostic (6.02e-2)" "unprognostic (2.77e-3)" ZNF799 "HIT-40, MGC71805, ZNF842" ENSG00000196466 "Zinc finger protein 799" Q96GE5 19 12390016-12401271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "HPA003150, HPA018683" Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "Centriolar satellite" "HPA003150: AB_1080725, HPA018683: AB_2669920" "unprognostic (2.96e-1)" "unprognostic (1.10e-1)" "unprognostic (8.84e-2)" "prognostic favorable (2.39e-4)" "unprognostic (3.63e-2)" "unprognostic (5.18e-3)" "unprognostic (3.02e-1)" "unprognostic (8.83e-3)" "unprognostic (4.47e-5)" "unprognostic (1.45e-1)" "unprognostic (5.56e-3)" "unprognostic (6.55e-2)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.04e-1)" "unprognostic (8.91e-3)" "unprognostic (1.23e-3)" ZNF80 pT17 ENSG00000174255 "Zinc finger protein 80" P51504 3 114234631-114237578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 5 "NK-cells: 3.6;Pancreatic endocrine cells: 3.4;T-cells: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enriched" "Detected in single" 6 "lymphoma: 1.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells" HPA065484 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "HPA065484: AB_2685496" "unprognostic (6.27e-3)" "unprognostic (3.00e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.52e-2)" "unprognostic (9.68e-5)" "unprognostic (5.36e-1)" "unprognostic (6.52e-3)" "unprognostic (2.80e-2)" "unprognostic (1.27e-2)" "unprognostic (6.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.69e-12)" "unprognostic (1.85e-1)" "unprognostic (3.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-2)" ZNF804B FLJ32110 ENSG00000182348 "Zinc finger protein 804B" A4D1E1 7 88759700-89338528 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.0;thyroid gland: 3.9" "Group enriched" "Detected in some" 13 "Excitatory neurons: 599.2;Inhibitory neurons: 260.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026702 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "HPA026702: AB_1859459" "unprognostic (1.10e-1)" "unprognostic (5.00e-2)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 6 "Excitatory neurons: 19.3;NK-cells: 29.9;T-cells: 53.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 1: T-cells - Immune response" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)"