Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
AOC3	"HPAO, VAP-1, VAP1"	ENSG00000131471	"Amine oxidase copper containing 3"	Q16853	17	42851184-42858130	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Cell adhesion"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 422.8"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 57.1;Fibroblasts: 23.5;Peritubular cells: 71.0;Sertoli cells: 55.3;Smooth muscle cells: 94.1;Theca cells: 48.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Smooth muscle cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"HPA000980, CAB025797"	Enhanced		Approved	"Golgi apparatus,Cytosol"	"Secreted - unknown location"	NA	NA		240000000		"Cluster 46: Fibroblasts - ECM organization"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 72: Smooth muscle cells - ECM organization"	Cytosol	"Golgi apparatus"	"CAB025797: , HPA000980: AB_1078170"	"unprognostic (2.20e-1)"	"unprognostic (4.49e-2)"	"prognostic unfavorable (3.68e-4)"	"unprognostic (2.97e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.64e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.15e-2)"	"unprognostic (1.48e-1)"	"unprognostic (4.00e-2)"	"unprognostic (2.95e-1)"	"unprognostic (9.02e-2)"	"prognostic unfavorable (1.79e-5)"	"unprognostic (5.61e-2)"	"unprognostic (1.67e-1)"	"unprognostic (8.39e-2)"	"prognostic unfavorable (6.98e-4)"
DCN	"DSPG2, SLRR1B"	ENSG00000011465	Decorin	P07585	12	91140484-91183217	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"			"Cancer-related genes, Corneal dystrophy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 1265.2;Fibroblasts: 6648.3;Leydig cells: 6373.4;Peritubular cells: 1909.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	9	"basophil: 24.5"	"Lineage enriched"	"Detected in single"	35	"granulocytes: 24.5"	"Cancer enriched"	"Detected in all"	4	"Rhabdoid: 698.3"	"Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Region enriched"	"Detected in all"	8	"spinal cord: 544.7"	"HPA003315, CAB017118, HPA064736, CAB068930"	Enhanced				"Secreted to extracellular matrix"	NA	NA		1900000	"Cluster 46: Basophils - DNA binding"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 65: Fibroblasts - ECM organization"			"CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340"	"unprognostic (1.73e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.43e-1)"	"unprognostic (3.22e-2)"	"unprognostic (8.63e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.01e-2)"	"unprognostic (2.68e-1)"	"unprognostic (1.98e-1)"	"unprognostic (6.12e-2)"	"unprognostic (1.65e-1)"	"unprognostic (5.15e-2)"	"prognostic unfavorable (1.46e-5)"	"unprognostic (3.06e-3)"	"unprognostic (5.37e-2)"	"unprognostic (1.59e-3)"	"unprognostic (7.56e-3)"
DKK3	"REIC, RIG"	ENSG00000050165	"Dickkopf WNT signaling pathway inhibitor 3"	Q9UBP4	11	11956207-12009769	"Plasma proteins, Predicted secreted proteins"	"Wnt signaling pathway"	"Developmental protein"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"heart muscle: 1224.0"	"Group enriched"	"Detected in many"	9	"Cardiomyocytes: 889.2;Muller glia cells: 1843.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"MAIT T-cell: 6.2;memory CD8 T-cell: 3.8"	"Lineage enriched"	"Detected in single"	62	"T-cells: 6.2"	"Cancer enhanced"	"Detected in many"		"Brain cancer: 325.0"	"Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA011868, CAB024949"	Approved		Supported	"Nuclear bodies,Vesicles,Cytosol"	"Secreted in other tissues"	No	No		18000000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 68: Muller glia cells - Visual perception"	Vesicles	"Nuclear bodies, Cytosol"	"CAB024949: , HPA011868: AB_1847716"	"unprognostic (4.24e-2)"	"unprognostic (6.40e-2)"	"unprognostic (1.96e-1)"	"unprognostic (7.84e-2)"	"unprognostic (3.06e-3)"	"unprognostic (6.58e-3)"	"unprognostic (1.14e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.31e-3)"	"unprognostic (5.28e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.87e-2)"	"prognostic unfavorable (6.31e-5)"	"unprognostic (7.41e-3)"	"unprognostic (1.09e-1)"	"unprognostic (2.97e-2)"	"unprognostic (1.02e-3)"
FBLN5	"ARMD3, DANCE, EVEC, UP50"	ENSG00000140092	"Fibulin 5"	Q9UBX5	14	91869411-91947987	"Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins"	"Cell adhesion"		"Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	7	"Fibroblasts: 214.7;Leydig cells: 626.8;Peritubular cells: 787.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 6.6"	"Group enriched"	"Detected in many"	19	"granulocytes: 6.6;T-cells: 1.8"	"Cancer enhanced"	"Detected in many"		"cervical cancer: 21.2"	"Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000848, HPA000868, CAB025843"	Supported		Uncertain	"Plasma membrane"	"Secreted to extracellular matrix"	NA	NA		12000000	"Cluster 46: Basophils - DNA binding"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 65: Fibroblasts - ECM organization"	"Plasma membrane"		"CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619"	"unprognostic (5.53e-3)"	"unprognostic (1.14e-1)"	"unprognostic (7.78e-2)"	"unprognostic (9.29e-2)"	"unprognostic (5.55e-3)"	"unprognostic (4.73e-2)"	"prognostic favorable (6.75e-4)"	"unprognostic (5.21e-3)"	"unprognostic (4.76e-2)"	"unprognostic (1.25e-2)"	"unprognostic (3.74e-2)"	"unprognostic (1.90e-1)"	"unprognostic (7.26e-2)"	"unprognostic (1.56e-3)"	"unprognostic (1.73e-1)"	"unprognostic (5.18e-2)"	"unprognostic (3.17e-3)"
