Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ADAP2	CENTA2	ENSG00000184060	"ArfGAP with dual PH domains 2"	Q9NPF8	17	30906344-30959322	"Predicted intracellular proteins"		"GTPase activation"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 101.7;Hofbauer cells: 191.2;Kupffer cells: 74.9;Macrophages: 126.5;monocytes: 55.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	9	"classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5"	"Group enriched"	"Detected in many"	9	"dendritic cells: 12.6;monocytes: 43.5"	"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Testis - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 69: Macrophages - Innate immune response"				"unprognostic (4.00e-2)"	"unprognostic (1.68e-2)"	"prognostic unfavorable (5.62e-4)"	"unprognostic (2.25e-1)"	"unprognostic (9.26e-2)"	"prognostic favorable (3.97e-4)"	"prognostic unfavorable (3.12e-4)"	"unprognostic (2.38e-1)"	"unprognostic (3.40e-1)"	"unprognostic (1.54e-1)"	"unprognostic (2.51e-1)"	"unprognostic (9.49e-2)"	"prognostic unfavorable (2.36e-6)"	"unprognostic (1.42e-1)"	"unprognostic (1.42e-2)"	"unprognostic (1.17e-2)"	"unprognostic (1.14e-2)"
AIF1	"AIF-1, Em:AF129756.17, IBA1, IRT-1"	ENSG00000204472	"Allograft inflammatory factor 1"	P55008	6	31615217-31617021	"Predicted intracellular proteins"		Actin-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 235.0;lymphoid tissue: 346.6"	"Group enriched"	"Detected in many"	7	"Hofbauer cells: 2459.1;Kupffer cells: 1902.8;Langerhans cells: 1685.0;Macrophages: 1457.6;monocytes: 3085.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	26	"classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5"	"Group enriched"	"Detected in all"	74	"dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5"	"Cancer enriched"	"Detected in some"	28	"Leukemia: 77.4"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049234, HPA062949"	Enhanced		Uncertain	Cytosol		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 2: Immune cells - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	Cytosol		"HPA049234: AB_2680685, HPA062949: AB_2732694"	"unprognostic (3.20e-2)"	"unprognostic (7.21e-3)"	"unprognostic (6.11e-2)"	"unprognostic (2.33e-2)"	"unprognostic (2.46e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.98e-2)"	"unprognostic (4.83e-2)"	"unprognostic (2.72e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.94e-1)"	"prognostic unfavorable (2.30e-5)"	"unprognostic (1.29e-1)"	"unprognostic (1.02e-2)"	"unprognostic (9.59e-2)"	"unprognostic (4.89e-2)"
C1QA		ENSG00000173372	"Complement C1q A chain"	P02745	1	22636628-22639678	"Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins"	"Complement pathway, Host-virus interaction, Immunity, Innate immunity"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 1092.6"	"Group enriched"	"Detected in many"	5	"Hofbauer cells: 1562.4;Kupffer cells: 1127.1;Macrophages: 2261.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	39	"intermediate monocyte: 226.1;non-classical monocyte: 181.7"	"Lineage enriched"	"Detected in many"	60	"monocytes: 226.1"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002350, CAB009823"	Supported				"Secreted to blood"	NA	NA		2700000000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 47: Retina - Visual perception"	"Cluster 69: Macrophages - Innate immune response"			"CAB009823: AB_2228238, HPA002350: AB_1078552"	"unprognostic (1.97e-1)"	"unprognostic (1.14e-2)"	"unprognostic (1.98e-3)"	"unprognostic (3.07e-2)"	"unprognostic (6.10e-2)"	"unprognostic (2.60e-1)"	"unprognostic (1.16e-1)"	"unprognostic (2.13e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.99e-1)"	"unprognostic (4.42e-2)"	"unprognostic (1.86e-1)"	"prognostic unfavorable (1.58e-6)"	"unprognostic (1.54e-1)"	"unprognostic (2.11e-3)"	"unprognostic (2.75e-2)"	"unprognostic (7.30e-2)"
C1QB		ENSG00000173369	"Complement C1q B chain"		1	22652762-22661637	"Human disease related genes, Predicted secreted proteins"				"Evidence at transcript level"	"Evidence at transcript level"			"Tissue enhanced"	"Detected in all"		"lung: 546.4;lymphoid tissue: 990.2"	"Group enriched"	"Detected in many"	8	"Hofbauer cells: 1355.4;Kupffer cells: 1035.4;Macrophages: 2260.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	71	"intermediate monocyte: 140.6;non-classical monocyte: 101.2"	"Lineage enriched"	"Detected in many"	85	"monocytes: 140.6"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA052116	Approved				"Secreted to blood"	NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 69: Macrophages - Innate immune response"			"HPA052116: AB_2681735"	"unprognostic (1.42e-1)"	"unprognostic (3.36e-2)"	"unprognostic (5.61e-3)"	"unprognostic (8.20e-2)"	"unprognostic (5.93e-2)"	"unprognostic (4.09e-1)"	"unprognostic (1.25e-1)"	"unprognostic (2.35e-1)"	"unprognostic (2.87e-2)"	"unprognostic (2.21e-1)"	"unprognostic (2.63e-2)"	"unprognostic (1.57e-1)"	"prognostic unfavorable (9.58e-6)"	"unprognostic (4.14e-2)"	"unprognostic (7.76e-3)"	"unprognostic (4.83e-2)"	"unprognostic (2.35e-2)"
C1QC	C1QG	ENSG00000159189	"Complement C1q C chain"	P02747	1	22643633-22648110	"Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins"	"Complement pathway, Immunity, Innate immunity"		"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 950.7"	"Group enriched"	"Detected in many"	4	"Hofbauer cells: 1168.5;Macrophages: 1118.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	5	"intermediate monocyte: 57.2"	"Lineage enriched"	"Detected in single"	541	"monocytes: 57.2"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001471, CAB009828"	Supported				"Secreted to blood"	NA	NA	513000000	2100000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 64: Macrophages - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 69: Macrophages - Innate immune response"			"CAB009828: AB_2067541, HPA001471: AB_1078553"	"unprognostic (2.97e-1)"	"unprognostic (6.80e-2)"	"unprognostic (2.40e-2)"	"unprognostic (1.84e-1)"	"unprognostic (7.40e-2)"	"unprognostic (2.38e-1)"	"unprognostic (1.98e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.66e-2)"	"unprognostic (7.44e-2)"	"unprognostic (2.75e-2)"	"unprognostic (1.32e-1)"	"prognostic unfavorable (1.17e-5)"	"unprognostic (1.06e-1)"	"unprognostic (1.63e-3)"	"unprognostic (2.21e-2)"	"unprognostic (3.73e-2)"
FCGR3A	"CD16, CD16a, FCG3, FCGR3"	ENSG00000203747	"Fc fragment of IgG receptor IIIa"	P08637	1	161541759-161550737	"CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins"	Immunity	"IgG-binding protein, Receptor"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lung: 206.3;lymphoid tissue: 306.8"	"Group enriched"	"Detected in many"	6	"Hofbauer cells: 243.9;Kupffer cells: 232.2;Macrophages: 324.9;monocytes: 901.8;NK-cells: 607.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7"	"Group enriched"	"Detected in all"	5	"granulocytes: 1169.8;monocytes: 3948.7"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages"									"CAB032435, HPA055431"	Supported				"Secreted to blood"	NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 69: Macrophages - Innate immune response"			"CAB032435: AB_626925, HPA055431: AB_2682815"	"unprognostic (5.27e-2)"	"unprognostic (9.95e-2)"	"unprognostic (2.37e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.82e-1)"	"unprognostic (2.24e-2)"	"unprognostic (6.06e-2)"	"unprognostic (2.41e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.98e-2)"	"unprognostic (7.52e-2)"	"prognostic unfavorable (3.22e-6)"	"unprognostic (1.14e-1)"	"unprognostic (4.66e-2)"	"unprognostic (1.03e-2)"	"unprognostic (7.51e-2)"
FOLR2	FRÃŽÂ²	ENSG00000165457	"Folate receptor beta"	P14207	11	72216601-72221950	"Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"	Transport	Receptor		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 168.4"	"Cell type enriched"	"Detected in many"	4	"Hofbauer cells: 997.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"classical monocyte: 64.2;intermediate monocyte: 50.6"	"Group enriched"	"Detected in many"	4	"dendritic cells: 18.7;monocytes: 64.2"	"Cancer enhanced"	"Detected in single"		"lymphoma: 3.8"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Secreted to blood"	NA	NA		15000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 64: Lymphoma - Humoral immune response"	"Cluster 69: Macrophages - Innate immune response"				"unprognostic (2.03e-1)"	"unprognostic (6.58e-3)"	"prognostic unfavorable (8.42e-4)"	"unprognostic (1.47e-1)"	"unprognostic (2.76e-1)"	"unprognostic (2.83e-1)"	"unprognostic (1.39e-1)"	"unprognostic (3.36e-1)"	"unprognostic (3.38e-1)"	"unprognostic (2.51e-1)"	"unprognostic (8.11e-2)"	"unprognostic (1.16e-1)"	"unprognostic (3.91e-3)"	"unprognostic (6.16e-3)"	"unprognostic (1.14e-1)"	"prognostic favorable (8.41e-4)"	"unprognostic (7.98e-3)"
IGSF6	DORA	ENSG00000140749	"Immunoglobulin superfamily member 6"	O95976	16	21639550-21652608	"Predicted membrane proteins"				"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 29.8"	"Group enriched"	"Detected in many"	10	"Hofbauer cells: 264.5;Kupffer cells: 171.3;Langerhans cells: 199.4;Macrophages: 321.3;monocytes: 246.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in some"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 1213.7"	"Lineage enhanced"	"Detected in all"		"granulocytes: 1213.7"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skin - Langerhans cells, Stomach - Macrophages"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA041023, HPA041072"	Uncertain					NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 64: Macrophages - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 19: Macrophages - Innate immune response"			"HPA041023: AB_10794434, HPA041072: AB_10794262"	"unprognostic (7.94e-2)"	"prognostic favorable (4.92e-4)"	"unprognostic (1.18e-2)"	"prognostic favorable (1.54e-5)"	"unprognostic (3.27e-1)"	"unprognostic (4.03e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.74e-2)"	"unprognostic (1.35e-2)"	"unprognostic (6.76e-2)"	"unprognostic (1.10e-1)"	"unprognostic (6.28e-2)"	"unprognostic (8.12e-2)"	"unprognostic (1.81e-1)"	"unprognostic (4.42e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.02e-1)"
KCNJ10	"Kir1.2, Kir4.1"	ENSG00000177807	"Potassium inwardly rectifying channel subfamily J member 10"	P78508	1	159998651-160070160	"Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Ion transport, Potassium transport, Transport"	"Ion channel, Voltage-gated channel"	"Deafness, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"brain: 100.7;kidney: 28.0;retina: 36.7"	"Group enriched"	"Detected in some"	7	"Astrocytes: 90.1;Muller glia cells: 67.2;Oligodendrocyte precursor cells: 34.2;Oligodendrocytes: 88.5"	"Cancer enriched"	"Detected in some"	6	"glioma: 27.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in single"		"skin cancer: 1.8"	"Kidney - Ascending Loop of Henle cells, Liver - Kupffer cells, Stomach - Parietal cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078302	Enhanced					NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 70: Brain - Nervous system development"	"Cluster 2: DU4475 - Unknown function"	"Cluster 68: Muller glia cells - Visual perception"			"HPA078302: AB_2732378"	"unprognostic (2.64e-2)"	"unprognostic (3.54e-3)"	"unprognostic (6.19e-2)"	"unprognostic (1.33e-1)"	"unprognostic (2.84e-1)"	"unprognostic (6.98e-4)"	"unprognostic (1.96e-1)"	"unprognostic (7.13e-2)"	"unprognostic (3.43e-1)"	"unprognostic (1.28e-3)"	"unprognostic (5.80e-4)"	"unprognostic (9.52e-2)"	"unprognostic (2.09e-2)"	"unprognostic (2.08e-2)"	"unprognostic (1.41e-1)"	"unprognostic (3.77e-1)"	"unprognostic (6.70e-3)"
LST1	"B144, D6S49E, LST-1"	ENSG00000204482	"Leukocyte specific transcript 1"	O00453	6	31586124-31588909	"Predicted intracellular proteins, Predicted membrane proteins"	"Cell shape, Immunity"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9"	"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 869.2;Kupffer cells: 1075.5;Langerhans cells: 1613.4;Macrophages: 784.1;monocytes: 3419.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"non-classical monocyte: 1746.7"	"Low lineage specificity"	"Detected in all"			"Cancer enriched"	"Detected in some"	16	"Leukemia: 40.1"	"Adipose visceral - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages"	"Low region specificity"	"Detected in all"							HPA079451			Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	"Plasma membrane, Cytosol"		"HPA079451: "	"unprognostic (1.08e-2)"	"prognostic favorable (7.89e-4)"	"unprognostic (6.99e-2)"	"unprognostic (4.16e-3)"	"unprognostic (3.13e-1)"	"unprognostic (3.92e-2)"	"unprognostic (3.65e-1)"	"unprognostic (7.06e-3)"	"unprognostic (2.81e-3)"	"unprognostic (2.12e-1)"	"unprognostic (1.70e-1)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (5.97e-5)"	"unprognostic (1.47e-1)"	"prognostic unfavorable (7.62e-4)"	"unprognostic (1.03e-1)"	"unprognostic (1.95e-1)"
MARCO	"SCARA2, SR-A6"	ENSG00000019169	"Macrophage receptor with collagenous structure"	Q9UEW3	2	118942194-118994660	"Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Immunity, Innate immunity"	Receptor		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 94.9;lung: 199.6;lymphoid tissue: 87.9"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 55.2;Hofbauer cells: 178.9;Kupffer cells: 84.2;Langerhans cells: 58.7;Macrophages: 285.7"	"Cancer enhanced"	"Detected in many"		"lung cancer: 21.6"	"Group enriched"	"Detected in many"	4	"cerebral cortex: 4.1;thalamus: 12.6"	"Group enriched"	"Detected in some"	4	"classical monocyte: 33.7;intermediate monocyte: 56.5"	"Lineage enriched"	"Detected in many"	5	"monocytes: 56.5"	"Cancer enhanced"	"Detected in some"		"Esophageal cancer: 1.3;head and neck cancer: 1.4;lymphoma: 1.5"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Thyroid - Macrophages"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA063793	Enhanced		Approved	"Golgi apparatus,Vesicles"		NA	NA		30000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 64: Macrophages - Immune response"	"Cluster 50: L-1236 & L-428 - Unknown function"	"Cluster 19: Macrophages - Innate immune response"	"Golgi apparatus"	Vesicles	"HPA063793: AB_2685123"	"unprognostic (1.30e-1)"	"unprognostic (1.61e-1)"	"unprognostic (5.96e-3)"	"unprognostic (3.36e-2)"	"unprognostic (1.71e-2)"	"unprognostic (3.58e-2)"	"unprognostic (3.67e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.95e-1)"	"unprognostic (2.83e-1)"	"unprognostic (6.27e-3)"	"unprognostic (5.13e-2)"	"unprognostic (2.24e-3)"	"unprognostic (1.80e-1)"	"unprognostic (1.09e-1)"	"unprognostic (1.40e-1)"	"unprognostic (6.55e-2)"
MS4A7	"CD20L4, CFFM4, MS4A8"	ENSG00000166927	"Membrane spanning 4-domains A7"	Q9GZW8	11	60378485-60395951	"Predicted intracellular proteins, Predicted membrane proteins"		Receptor		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 196.6"	"Group enriched"	"Detected in many"	5	"Hofbauer cells: 372.7;Kupffer cells: 305.4;Macrophages: 613.9;monocytes: 1048.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"intermediate monocyte: 747.4;non-classical monocyte: 1486.0"	"Lineage enriched"	"Detected in many"	12	"monocytes: 1486.0"	"Cancer enhanced"	"Detected in some"		"Leukemia: 7.4"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"HPA017418, CAB026387"	Approved					NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 19: Macrophages - Innate immune response"			"CAB026387: , HPA017418: AB_1854137"	"unprognostic (1.43e-1)"	"unprognostic (2.60e-3)"	"unprognostic (3.24e-2)"	"unprognostic (9.67e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.81e-1)"	"unprognostic (1.04e-1)"	"unprognostic (9.51e-2)"	"unprognostic (3.02e-2)"	"unprognostic (4.85e-2)"	"unprognostic (5.79e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.43e-2)"	"unprognostic (4.59e-2)"	"unprognostic (3.90e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.03e-1)"
SIGLEC1	"CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN"	ENSG00000088827	"Sialic acid binding Ig like lectin 1"	Q9BZZ2	20	3686970-3712600	"CD markers, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion, Endocytosis"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	6	"Hofbauer cells: 77.2;Macrophages: 55.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"classical monocyte: 1.5"	"Lineage enhanced"	"Detected in single"		"monocytes: 1.5"	"Not detected"	"Not detected"			"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA053457	Supported				"Intracellular and membrane"	NA	NA		260000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 19: Lung - Lung function"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 69: Macrophages - Innate immune response"			"HPA053457: AB_2682158"	"unprognostic (2.05e-1)"	"unprognostic (9.27e-3)"	"unprognostic (3.83e-4)"	"unprognostic (4.87e-3)"	"unprognostic (3.40e-2)"	"unprognostic (1.06e-1)"	"unprognostic (2.15e-1)"	"unprognostic (6.98e-2)"	"unprognostic (2.27e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.57e-1)"	"prognostic unfavorable (8.69e-5)"	"unprognostic (8.71e-2)"	"prognostic unfavorable (4.36e-4)"	"unprognostic (1.11e-2)"	"unprognostic (9.31e-2)"
UCP2	"BMIQ4, SLC25A8"	ENSG00000175567	"Uncoupling protein 2"	P55851	11	73974672-73982843	"Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters"	Transport			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 278.1"	"Cell type enhanced"	"Detected in many"		"B-cells: 257.9;dendritic cells: 535.5;Erythroid cells: 450.9;Hofbauer cells: 448.8;monocytes: 280.1;NK-cells: 334.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in all"		"lymphoma: 245.9"	"Adipose subcutaneous - Macrophages, Adipose visceral - Adipocytes (Visceral), Liver - Kupffer cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025583, HPA075202"	Approved		Supported	Mitochondria		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 23: Langerhans cells - Immune response"	Mitochondria		"CAB025583: , HPA075202: AB_2732284"	"unprognostic (1.13e-1)"	"prognostic favorable (4.65e-5)"	"unprognostic (8.07e-2)"	"unprognostic (1.21e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.15e-2)"	"unprognostic (1.92e-1)"	"unprognostic (1.82e-3)"	"unprognostic (2.07e-1)"	"unprognostic (4.59e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (7.80e-6)"	"unprognostic (3.77e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.77e-3)"	"unprognostic (3.88e-3)"
