Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1264.3;Cardiomyocytes: 398.0;Endothelial cells: 864.5;Hepatocytes: 661.1;Kupffer cells: 338.8;Microglial cells: 345.7;Smooth muscle cells: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;liver cancer: 139.1;skin cancer: 83.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: Liver cancer - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 151.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 69: Macrophages - Innate immune response" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 30.2;Proximal enterocytes: 19.5;Proximal tubular cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 12.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in all" "Early spermatids: 236.4;Hepatocytes: 1012.8;Late spermatids: 534.6;monocytes: 273.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 6 "Breast myoepithelial cells: 539.9;Smooth muscle cells: 498.4" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 84.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;parathyroid gland: 82.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 82.1;Excitatory neurons: 404.1;Inhibitory neurons: 231.6;Late spermatids: 60.8;Oligodendrocyte precursor cells: 121.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "Myeloma: 43.7" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" NA NA 890000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: Myeloma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.0;Fibroblasts: 10.4;Granulosa cells: 22.2;Theca cells: 18.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA061013 Approved Vesicles "Secreted to extracellular matrix" NA No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA061013: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;heart muscle: 105.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 94.1;Excitatory neurons: 33.5;Horizontal cells: 38.5;Inhibitory neurons: 42.9;Oligodendrocytes: 84.7;Paneth cells: 55.2;Peritubular cells: 71.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in all" 5 "basal ganglia: 388.0" "Region enriched" "Detected in all" 6 "basal ganglia: 155.9" "HPA017730, HPA077682" Uncertain Approved "Vesicles,Intermediate filaments" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 65: Breast cancer - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Intermediate filaments" Vesicles "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 29.4;epididymis: 22.8" "Group enriched" "Detected in some" 5 "Astrocytes: 147.1;Inhibitory neurons: 245.5;Oligodendrocyte precursor cells: 132.9" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.6;Rhabdoid: 1.0" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 37: Neurons - Neuronal signaling" "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1739.4;Excitatory neurons: 3790.8;Inhibitory neurons: 2675.1;Oligodendrocyte precursor cells: 1950.0;Oligodendrocytes: 1142.7" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.0" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 890.6;Inhibitory neurons: 631.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 325.3" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" AGBL1 "CCP4, FLJ32310" ENSG00000273540 "ATP/GTP binding protein like 1" Q96MI9 15 86079871-87049169 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 7.8;tongue: 23.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.4;Astrocytes: 27.8;Excitatory neurons: 15.5;Inhibitory neurons: 25.2;Oligodendrocyte precursor cells: 45.2;Skeletal myocytes: 46.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "unprognostic (3.70e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" AHCYL2 "IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 488.0;intestine: 177.4" "Cell type enhanced" "Detected in many" "Astrocytes: 549.8;Distal enterocytes: 229.9;Excitatory neurons: 129.3;Inhibitory neurons: 113.0;Oligodendrocyte precursor cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol NA NA 500000 "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 50: Enterocytes - Absorption" Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favorable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favorable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 249.0;Basal squamous epithelial cells: 284.7;Squamous epithelial cells: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 157.4" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Myeloma: 63.1" "Breast - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Skeletal myocytes, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Cell type enhanced" "Detected in many" "Astrocytes: 58.5;Fibroblasts: 30.0;Inhibitory neurons: 36.8;Serous glandular cells: 32.8;Smooth muscle cells: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 43.8" "Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 72: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 469.5;Excitatory neurons: 846.0;Inhibitory neurons: 859.4;Oligodendrocyte precursor cells: 567.5;Oligodendrocytes: 1491.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 108.1;Astrocytes: 63.6;Inhibitory neurons: 27.4;Microglial cells: 26.5;Oligodendrocyte precursor cells: 36.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 10.3" "Colon - Enteric glia cells, Lung - Alveolar cells type 1, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: BEWO - Unknown function" "Cluster 32: Neurons - Synaptic function" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 24.5;Basal respiratory cells: 41.0;Basal squamous epithelial cells: 37.2;Squamous epithelial cells: 133.2;Suprabasal keratinocytes: 41.2;Thymic epithelial cells: 55.2" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 156.9;head and neck cancer: 228.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Skin - Keratinocyte (other)" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 322.2;NK-cells: 230.9;Syncytiotrophoblasts: 844.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 93.9;lymphoid tissue: 48.3;urinary bladder: 24.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 92.8;Hofbauer cells: 134.5;Kupffer cells: 76.9;Langerhans cells: 47.0;Macrophages: 48.9;monocytes: 172.9;Serous glandular cells: 82.1;Squamous epithelial cells: 56.1;Suprabasal keratinocytes: 122.3" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1014.5" "Lineage enriched" "Detected in many" 8 "monocytes: 1014.5" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 8.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.4;intestine: 12.1" "Cell type enhanced" "Detected in some" "Ductal cells: 10.9;Erythroid cells: 8.7;Pancreatic endocrine cells: 8.6;Plasma cells: 24.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung)" "HPA056980, HPA066719" Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 34731.7" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cancer enhanced" "Detected in all" "Leukemia: 229.9;liver cancer: 258.0" "Liver - Hepatocytes, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 8379.2;Hofbauer cells: 5636.7;Leydig cells: 2655.2;Melanocytes: 3312.6;Muller glia cells: 8525.9;Peritubular cells: 4801.9;Proximal tubular cells: 6176.1;Theca cells: 8535.1" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 529.4" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 12: Non-specific - Chromatin organization" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1573.3;Basal squamous epithelial cells: 1021.8;Collecting duct cells: 1086.9;Squamous epithelial cells: 2389.1;Suprabasal keratinocytes: 2174.6" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 392.4" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.8;Ductal cells: 25.3;Exocrine glandular cells: 26.0;Undifferentiated cells: 21.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Not detected" "Not detected" HPA069694 Approved NA No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "HPA069694: AB_2686173" "unprognostic (4.14e-1)" "unprognostic (1.21e-2)" "unprognostic (6.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-2)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (8.78e-3)" "unprognostic (9.58e-2)" "unprognostic (7.65e-6)" "unprognostic (8.59e-2)" "unprognostic (3.29e-1)" "unprognostic (2.32e-2)" "unprognostic (2.22e-2)" ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 65.0;Extravillous trophoblasts: 66.1;Gastric mucus-secreting cells: 57.2;Intestinal goblet cells: 57.0;Paneth cells: 49.2;Proximal enterocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" ARHGEF4 "ASEF, KIAA1112, STM6" ENSG00000136002 "Rho guanine nucleotide exchange factor 4" Q9NR80 2 130836914-131047263 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.3;skin 1: 39.8" "Cell type enhanced" "Detected in many" "Astrocytes: 323.0;Excitatory neurons: 81.8;Horizontal cells: 64.1;Inhibitory neurons: 81.6;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 12 "dendritic cells: 1.0;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 18.4" "Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes" HPA018267 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA018267: AB_1845006" "unprognostic (2.30e-3)" "unprognostic (8.84e-2)" "unprognostic (5.32e-2)" "unprognostic (1.18e-2)" "unprognostic (4.44e-1)" "unprognostic (2.60e-2)" "unprognostic (4.69e-2)" "unprognostic (2.14e-2)" "unprognostic (8.97e-2)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.68e-2)" "prognostic favorable (7.00e-4)" "unprognostic (3.93e-3)" "unprognostic (9.71e-3)" ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in many" "Astrocytes: 44.9;Excitatory neurons: 36.6;Inhibitory neurons: 36.8;Microglial cells: 31.0;Oligodendrocyte precursor cells: 63.5;Theca cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Lung - Fibroblast_2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 56: Neurons - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 313.9;Kupffer cells: 225.1;Langerhans cells: 205.6;Macrophages: 224.2;monocytes: 307.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Plasma membrane" Cytosol "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 38.0;Erythroid cells: 35.6;Extravillous trophoblasts: 35.7;Late spermatids: 35.4;Spermatocytes: 89.9;Spermatogonia: 69.4;Undifferentiated cells: 43.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 773.1" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cancer enriched" "Detected in some" 12 "liver cancer: 103.7" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Hepatocytes, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Intellectual disability, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1482.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1731.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 59: Proximal enterocytes - Transmembrane transport" "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169132722 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Immunity, Innate immunity, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1337.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 1563.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 2100000 "Cluster 27: Non-specific - Gene expression" "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "HPA012911: AB_1845173" "unprognostic (4.20e-2)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (1.95e-1)" "unprognostic (5.34e-2)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (6.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "prognostic favorable (7.08e-7)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (1.97e-3)" "unprognostic (9.39e-2)" ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 291.7;Inhibitory neurons: 250.0;Oligodendrocytes: 1149.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 17.6" "Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.6;Early spermatids: 46.0;Erythroid cells: 54.7;Extravillous trophoblasts: 69.6;Spermatocytes: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 248.9;Endometrial ciliated cells: 105.2;Late spermatids: 181.7;Respiratory ciliated cells: 125.7;Spermatocytes: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Non-specific - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA022957: AB_1848220" "unprognostic (3.13e-2)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.66e-3)" "unprognostic (9.82e-3)" "unprognostic (1.37e-2)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "prognostic favorable (4.14e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.8" "Cell type enhanced" "Detected in many" "Melanocytes: 264.7;Mucus glandular cells: 252.0;Syncytiotrophoblasts: 528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cancer enhanced" "Detected in many" "skin cancer: 46.1" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Enzymes" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 81.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 167.3;Breast myoepithelial cells: 167.9;Granulosa cells: 319.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 357.8" "Lung - Fibroblast_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 6: BEWO - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: AB_2668371, HPA010866: AB_10601686" "unprognostic (7.02e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-2)" "unprognostic (3.17e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (9.42e-6)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-3)" "unprognostic (9.29e-2)" "prognostic favorable (5.25e-4)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (2.38e-2)" "unprognostic (2.10e-2)" BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 245.5;Rod photoreceptor cells: 62.2;Spermatocytes: 49.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA046125 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "HPA046125: AB_2679549" "unprognostic (4.37e-2)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (1.21e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-1)" "unprognostic (5.83e-2)" "unprognostic (2.35e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.55e-1)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (1.67e-1)" BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in many" "Adipocytes: 363.1;Basal respiratory cells: 438.9;Collecting duct cells: 494.2;Cytotrophoblasts: 694.8;Syncytiotrophoblasts: 411.6" "Cancer enhanced" "Detected in all" "ovarian cancer: 493.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 18000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 28: Cytotrophoblasts - Unknown function" "Nucleoli fibrillar center" "HPA005654: AB_2667378" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (2.61e-3)" "unprognostic (1.41e-1)" "prognostic favorable (5.94e-6)" "unprognostic (1.83e-2)" "unprognostic (5.74e-2)" "unprognostic (2.14e-2)" "unprognostic (9.97e-3)" BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175510-112224699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.2;liver: 52.3;retina: 55.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.3;Hepatocytes: 67.9;Rod photoreceptor cells: 264.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061542 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "HPA061542: " "unprognostic (2.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (7.60e-3)" "unprognostic (1.88e-1)" "unprognostic (3.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.7;Bipolar cells: 9.8;Cardiomyocytes: 11.6;Excitatory neurons: 22.0;Skeletal myocytes: 7.9;Smooth muscle cells: 13.1;Theca cells: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB009564 Enhanced "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 18: Non-specific - Mixed function" "CAB009564: AB_2064213" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 194.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 472.7;Muller glia cells: 248.0;Proximal tubular cells: 201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.7;NK-cells: 62.0;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 68: Epididymis - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 35: Bipolar cells - Visual perception" Cytosol "HPA045384: AB_2679305, HPA078630: " "unprognostic (7.56e-2)" "unprognostic (7.08e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (8.54e-7)" "unprognostic (3.21e-1)" "unprognostic (1.65e-1)" "unprognostic (4.27e-2)" "prognostic favorable (1.52e-4)" "unprognostic (7.36e-3)" "unprognostic (6.82e-2)" "unprognostic (8.22e-3)" "unprognostic (6.63e-2)" "prognostic favorable (3.05e-13)" "unprognostic (4.14e-3)" "unprognostic (6.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" BIN2 BRAP-1 ENSG00000110934 "Bridging integrator 2" Q9UBW5 12 51281038-51324668 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 101.3;lymphoid tissue: 48.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.1;Extravillous trophoblasts: 199.7;monocytes: 168.6;NK-cells: 422.6;Syncytiotrophoblasts: 146.9;T-cells: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 51.4;Myeloma: 46.7" "Kidney - T-cells, Lung - Neutrophil_2, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038666, HPA038667" Enhanced Enhanced "Plasma membrane" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA038666: AB_2676139, HPA038667: AB_2676140" "unprognostic (8.44e-3)" "prognostic favorable (1.33e-4)" "unprognostic (2.48e-1)" "prognostic favorable (6.34e-4)" "unprognostic (4.63e-1)" "unprognostic (2.00e-3)" "unprognostic (1.21e-1)" "unprognostic (3.59e-2)" "unprognostic (3.72e-2)" "unprognostic (7.47e-2)" "unprognostic (5.71e-2)" "unprognostic (3.29e-1)" "unprognostic (1.65e-3)" "unprognostic (4.03e-1)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-1)" BLACAT1 "linc-UBC1, LINC00912, onco-lncRNA-30" ENSG00000281406 "Bladder cancer associated transcript 1" 1 205434885-205457091 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.7;epididymis: 3.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.2;Collecting duct cells: 9.8;Horizontal cells: 3.8;Mucus glandular cells: 3.2;Salivary duct cells: 2.5;Sertoli cells: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Sertoli cells" NA NA "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (3.01e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-3)" "unprognostic (5.22e-2)" "unprognostic (7.97e-2)" "unprognostic (5.59e-2)" "unprognostic (5.02e-2)" "unprognostic (2.13e-2)" "unprognostic (7.37e-3)" "unprognostic (5.36e-2)" "unprognostic (6.23e-7)" "unprognostic (3.09e-2)" "unprognostic (6.78e-2)" "unprognostic (1.84e-2)" "unprognostic (4.59e-1)" BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.2;lung: 18.3;pituitary gland: 12.1" "Group enriched" "Detected in some" 4 "Club cells: 974.3;Ionocytes: 627.1;Serous glandular cells: 541.7" "Cancer enriched" "Detected in many" 27 "lung cancer: 262.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "pancreatic cancer: 30.9" "Lung - Respiratory ciliated cells" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" NA NA 1200000 "Cluster 19: Lung - Lung function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "CAB025669: " "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 447.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 60.9;Ductal cells: 59.8;Exocrine glandular cells: 66.3;Serous glandular cells: 111.4;Suprabasal keratinocytes: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm Cytosol "HPA042889: AB_10795515, HPA077485: " "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.20e-3)" "unprognostic (1.68e-1)" "unprognostic (2.10e-3)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "prognostic favorable (4.56e-14)" "unprognostic (1.15e-3)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-1)" BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.1;Granulosa cells: 70.9;Plasma cells: 46.8;Spermatocytes: 91.3;Spermatogonia: 21.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" C1orf226 FLJ13137 ENSG00000239887 "Chromosome 1 open reading frame 226" A1L170 1 162378841-162386812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 15.5;Early spermatids: 18.3;Hepatocytes: 26.1;Late spermatids: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "HPA052251, HPA074060" Approved Approved Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA052251: AB_2681775, HPA074060: " "prognostic favorable (2.60e-4)" "unprognostic (1.30e-1)" "unprognostic (2.69e-2)" "unprognostic (1.59e-2)" "unprognostic (6.71e-3)" "unprognostic (9.80e-2)" "unprognostic (8.55e-2)" "unprognostic (1.65e-1)" "unprognostic (2.05e-1)" "unprognostic (4.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-3)" "prognostic favorable (4.44e-5)" "unprognostic (9.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.13e-4)" C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1562.4;Kupffer cells: 1127.1;Macrophages: 2261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 47: Retina - Visual perception" "Cluster 69: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 8 "Hofbauer cells: 1355.4;Kupffer cells: 1035.4;Macrophages: 2260.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 4 "Hofbauer cells: 1168.5;Macrophages: 1118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 641.9;Hepatocytes: 3195.0;Kupffer cells: 731.3;Thymic epithelial cells: 2259.7" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Cancer enhanced" "Detected in many" "liver cancer: 248.6" "Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 29: Hepatocytes - Metabolism" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.4;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.6;Basal squamous epithelial cells: 51.1;Gastric mucus-secreting cells: 57.8;Intestinal goblet cells: 61.5;Syncytiotrophoblasts: 82.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 5 "Fibroblasts: 708.6;Leydig cells: 1128.7;Theca cells: 421.0" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Neuroblastoma: 31.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" CA1 Car1 ENSG00000133742 "Carbonic anhydrase 1" P00915 8 85327608-85379014 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 55 "bone marrow: 1798.9;intestine: 2109.9" "Group enriched" "Detected in some" 21 "Distal enterocytes: 3094.2;Erythroid cells: 8956.3" "Group enriched" "Detected in some" 10 "colorectal cancer: 3.4;stomach cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "Leukemia: 110.4" "Colon - Colon enterocytes, Liver - Erythroid cells, Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006558, CAB025790" Enhanced NA NA 4600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "CAB025790: , HPA006558: AB_1845989" "unprognostic (1.44e-1)" "unprognostic (7.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.84e-2)" "unprognostic (2.03e-2)" "unprognostic (1.73e-2)" "unprognostic (6.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (5.61e-2)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 39.9;Alveolar cells type 2: 121.1;Horizontal cells: 61.5;Inhibitory neurons: 35.2" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.3;thyroid cancer: 12.8" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 41: Alveolar cells - Lung function" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" CACNB1 CACNLB1 ENSG00000067191 "Calcium voltage-gated channel auxiliary subunit beta 1" Q02641 17 39173453-39197703 "FDA approved drug targets, Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 328.8;tongue: 216.0" "Cell type enriched" "Detected in many" 7 "Skeletal myocytes: 153.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023343 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 65: Breast cancer - Unknown function" "Cluster 27: Skeletal myocytes - Muscle contraction" "HPA023343: AB_1845866" "unprognostic (3.44e-2)" "unprognostic (1.89e-2)" "unprognostic (1.69e-3)" "prognostic unfavorable (3.80e-4)" "unprognostic (3.99e-2)" "unprognostic (1.52e-2)" "unprognostic (1.37e-2)" "unprognostic (2.80e-3)" "unprognostic (4.43e-1)" "unprognostic (1.04e-3)" "unprognostic (5.98e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-11)" "unprognostic (7.62e-2)" "unprognostic (2.30e-1)" "unprognostic (1.34e-2)" "unprognostic (7.44e-3)" CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.4;skin 1: 7.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 488.2;Horizontal cells: 108.9;Inhibitory neurons: 461.0;Microglial cells: 133.2;Oligodendrocyte precursor cells: 148.7" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 6: Brain - Smell perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "HPA015601: AB_1845873" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.49e-2)" "unprognostic (3.70e-1)" "unprognostic (9.42e-4)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.55e-2)" "unprognostic (7.26e-3)" "unprognostic (3.93e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" CADM1 "BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1" ENSG00000182985 "Cell adhesion molecule 1" Q9BY67 11 115169218-115504957 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 287.7" "Cell type enhanced" "Detected in many" "Astrocytes: 950.2;Bipolar cells: 525.1;Muller glia cells: 428.5;Oligodendrocyte precursor cells: 647.9;Oligodendrocytes: 587.9;Rod photoreceptor cells: 766.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.0;myeloid DC: 8.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.1;T-cells: 8.0" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037266 Enhanced Supported "Cell Junctions" NA NA 220000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" "Cell Junctions" "CAB037266: AB_532287" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "prognostic favorable (1.32e-4)" "unprognostic (4.11e-3)" "unprognostic (1.50e-1)" "unprognostic (2.75e-3)" "unprognostic (1.13e-2)" "unprognostic (1.77e-1)" "unprognostic (2.67e-1)" "unprognostic (6.61e-3)" "unprognostic (9.22e-2)" "unprognostic (2.92e-3)" "unprognostic (1.77e-2)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (5.40e-2)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.3;Excitatory neurons: 35.0;Horizontal cells: 56.4;Inhibitory neurons: 39.5;Melanocytes: 64.4;Muller glia cells: 32.5;Schwann cells: 89.8" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 54.1;skin cancer: 22.2" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 666.1;Cone photoreceptor cells: 305.0;Excitatory neurons: 817.6;Horizontal cells: 239.7;Inhibitory neurons: 1128.7;Oligodendrocyte precursor cells: 255.6" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.0" "Colon - Colon enteroendocrine cells, Lung - Mast cells, Skin - Fibroblast_2" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Group enriched" "Detected in many" 5 "granulocytes: 129.0;Thymic epithelial cells: 489.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 39.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Mast cells, Stomach - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 46: Granulocytes - Mast cell degranulation" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.5;Fibroblasts: 37.8;Hofbauer cells: 49.1;Leydig cells: 45.8;monocytes: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.8;Gastric mucus-secreting cells: 22.7;Paneth cells: 12.4;Proximal enterocytes: 23.6;Proximal tubular cells: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 184.3;non-classical monocyte: 216.9" "Lineage enriched" "Detected in many" 7 "monocytes: 216.9" "Cancer enhanced" "Detected in all" "Myeloma: 77.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 461.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 466.6;Distal tubular cells: 314.1;Intestinal goblet cells: 456.6;Paneth cells: 283.2;Proximal tubular cells: 486.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075200 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA075200: " "unprognostic (1.67e-1)" "unprognostic (2.70e-3)" "unprognostic (9.71e-3)" "unprognostic (3.13e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (1.37e-7)" "prognostic unfavorable (5.49e-4)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.48e-3)" "unprognostic (1.93e-2)" "unprognostic (1.40e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-2)" CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043830 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: Liver cancer - Metabolism" "Cluster 30: Breast - Lactation" "HPA043830: AB_10795879" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 631.8;Hofbauer cells: 1060.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Supported Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 19: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 514.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 2800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 13 "Gastric mucus-secreting cells: 825.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 29.2;colorectal cancer: 29.2;Gastric cancer: 36.3" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 58: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2061.1;Alveolar cells type 1: 1354.7;Basal keratinocytes: 839.9;Endothelial cells: 1053.2;Smooth muscle cells: 716.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.6;Fibroblasts: 20.6;Rod photoreceptor cells: 44.2;Sertoli cells: 19.3;Theca cells: 56.2;Thymic epithelial cells: 25.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 38.4" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_2" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" CCDC89 FLJ38159 ENSG00000179071 "Coiled-coil domain containing 89" Q8N998 11 85683848-85686195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 43.6" "Cell type enriched" "Detected in many" 6 "Early spermatids: 509.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.9" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040628 Enhanced Approved Nucleoplasm NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA040628: AB_2677053" "unprognostic (5.81e-2)" "unprognostic (1.93e-1)" "unprognostic (1.99e-1)" "unprognostic (3.04e-2)" "unprognostic (5.37e-2)" "unprognostic (6.38e-2)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (2.00e-1)" "unprognostic (2.41e-3)" "unprognostic (7.75e-3)" "unprognostic (5.10e-2)" "unprognostic (8.47e-2)" "unprognostic (3.52e-1)" CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 5 "Extravillous trophoblasts: 824.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 54: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.5;Extravillous trophoblasts: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: Non-specific - Transcription" "Cluster 43: Non-specific - Cell proliferation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" CCNI CCNI1 ENSG00000118816 "Cyclin I" Q14094 4 77047155-77076309 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010206, HPA039853, HPA061470" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 15: Smooth muscle cells - Muscle contraction" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "CAB010206: AB_2073599, HPA039853: AB_2676710, HPA061470: AB_2684533" "unprognostic (3.68e-1)" "unprognostic (2.25e-1)" "unprognostic (7.59e-2)" "unprognostic (1.11e-1)" "unprognostic (4.64e-2)" "unprognostic (1.38e-1)" "unprognostic (8.57e-3)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.10e-4)" "unprognostic (3.81e-2)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 99.1;Thymic epithelial cells: 145.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 50: Enterocytes - Absorption" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370854-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 10.3;Langerhans cells: 41.3;Macrophages: 11.6;T-cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 39.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 1.5;Myeloma: 1.4" "Lung - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2691.3;Exocrine glandular cells: 1866.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Thyroid - Thyroid glandular cells" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 68: Kidney - Mixed function" "Cluster 30: Breast - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 22 "NK-cells: 788.2;T-cells: 243.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 24 "Leukemia: 23.3;lymphoma: 24.2;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.0;lung: 17.7;lymphoid tissue: 28.9" "Group enriched" "Detected in some" 5 "Hofbauer cells: 41.6;Kupffer cells: 30.0;Macrophages: 39.0;monocytes: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 234.2" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.2;monocytes: 193.0" "Cancer enriched" "Detected in single" 62 "Leukemia: 18.8" "Lung - Macrophages" "Low region specificity" "Detected in some" HPA013712 Supported NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "HPA013712: AB_2668874" "unprognostic (6.51e-2)" "unprognostic (1.49e-3)" "unprognostic (3.81e-2)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (9.60e-2)" "unprognostic (4.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.79e-2)" CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 68.6;Hofbauer cells: 91.5;Kupffer cells: 67.0;Langerhans cells: 50.7;Macrophages: 62.0;monocytes: 91.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cancer enriched" "Detected in many" 7 "Leukemia: 52.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 9 "T-cells: 77.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cancer enriched" "Detected in single" 14 "Leukemia: 2.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321532-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1461.4;monocytes: 950.6;Syncytiotrophoblasts: 882.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 662.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" NA No 32300000 360000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" "CAB010454: AB_2075970, HPA002190: AB_1078472, HPA024386: AB_1846319" "unprognostic (4.08e-2)" "unprognostic (3.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (3.41e-2)" "unprognostic (2.04e-1)" "unprognostic (9.70e-2)" "unprognostic (2.33e-2)" CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 226.4;Kupffer cells: 162.8;Langerhans cells: 81.8;Macrophages: 192.6;Proximal enterocytes: 196.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Cell type enriched" "Detected in many" 6 "T-cells: 154.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Group enriched" "Detected in some" 8 "Leukemia: 8.8;Myeloma: 33.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 193.5;esophagus: 87.1;liver: 86.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 247.8;Hepatocytes: 136.8;Kupffer cells: 93.1;monocytes: 75.0;Paneth cells: 147.4;Proximal enterocytes: 119.0;Suprabasal keratinocytes: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1234.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 1234.7" "Cancer enhanced" "Detected in many" "cervical cancer: 197.6" "Lung - Neutrophil_2, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.6;Distal enterocytes: 29.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.7;Erythroid cells: 49.3;Extravillous trophoblasts: 80.9;Proximal enterocytes: 68.8;Spermatocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 258.8;Distal enterocytes: 274.4;Glandular and luminal cells: 317.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 275.8" "Group enriched" "Detected in many" 4 "Late spermatids: 706.3;Proximal enterocytes: 500.1" "Group enriched" "Detected in many" 14 "colorectal cancer: 9.1;liver cancer: 5.7;pancreatic cancer: 11.7;renal cancer: 8.6;stomach cancer: 9.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 4.6;Gastric cancer: 6.5;liver cancer: 4.1;pancreatic cancer: 9.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "hypothalamus: 2.1" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 8800000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA012569: AB_1845298, HPA017053: AB_1845297" "unprognostic (1.34e-2)" "unprognostic (8.90e-4)" "unprognostic (3.82e-2)" "unprognostic (8.51e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (6.66e-2)" "unprognostic (2.06e-3)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (7.66e-3)" "unprognostic (1.75e-1)" "prognostic favorable (9.29e-4)" "unprognostic (6.58e-2)" "unprognostic (3.55e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75576496-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.3;choroid plexus: 8.6;retina: 9.6;testis: 11.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 50.0;Early spermatids: 77.9;Horizontal cells: 35.2;Inhibitory neurons: 40.0;Oligodendrocytes: 43.8;Spermatocytes: 95.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 139.7;Respiratory ciliated cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Group enriched" "Detected in some" 7 "Hofbauer cells: 9.5;Kupffer cells: 30.4;Macrophages: 22.3;monocytes: 16.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.8" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 86.9;Spermatocytes: 245.3;Spermatogonia: 191.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 126.5;Erythroid cells: 77.2;Plasma cells: 74.5;Respiratory ciliated cells: 56.3;Undifferentiated cells: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 50.8" "Group enriched" "Detected in many" 6 "B-cells: 38.6;T-cells: 50.8" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 17: RS4;11 - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "HPA042404: AB_2677981" "unprognostic (3.78e-2)" "prognostic favorable (3.40e-5)" "unprognostic (7.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.50e-5)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.99e-7)" "unprognostic (9.54e-3)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (5.61e-2)" CEP126 KIAA1377 ENSG00000110318 "Centrosomal protein 126" Q9P2H0 11 101915010-102001062 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 144.1;Excitatory neurons: 123.2;Horizontal cells: 114.7;Respiratory ciliated cells: 142.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038381, HPA038399" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Cytosol" "HPA038381: AB_10669780, HPA038399: AB_10670157" "unprognostic (7.61e-2)" "unprognostic (6.75e-2)" "unprognostic (9.07e-2)" "unprognostic (1.02e-2)" "unprognostic (9.31e-2)" "unprognostic (8.87e-2)" "unprognostic (1.55e-4)" "unprognostic (1.52e-2)" "unprognostic (5.77e-2)" "unprognostic (9.55e-2)" "unprognostic (7.72e-3)" "unprognostic (8.87e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.30e-2)" "unprognostic (3.41e-1)" "unprognostic (9.61e-2)" "unprognostic (6.99e-3)" CEP70 "BITE, FLJ13036" ENSG00000114107 "Centrosomal protein 70" Q8NHQ1 3 138494344-138594538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.7;Endometrial ciliated cells: 121.8;Late spermatids: 303.8;Spermatocytes: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 2.8;MAIT T-cell: 3.3;memory B-cell: 1.7;memory CD4 T-cell: 2.1;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.1;naive CD8 T-cell: 4.0;NK-cell: 2.3;T-reg: 1.3" "Group enriched" "Detected in many" 10 "B-cells: 1.7;NK-cells: 2.3;T-cells: 4.1" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036941, HPA036942" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Cytosol" Centrosome "HPA036941: AB_10670567, HPA036942: AB_10670957" "unprognostic (1.61e-1)" "prognostic favorable (2.93e-4)" "unprognostic (2.27e-2)" "unprognostic (3.59e-2)" "unprognostic (3.31e-2)" "unprognostic (3.44e-2)" "unprognostic (1.95e-2)" "unprognostic (9.92e-3)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (5.01e-3)" "prognostic unfavorable (9.60e-5)" "unprognostic (8.90e-3)" "unprognostic (8.07e-3)" "unprognostic (1.46e-1)" "unprognostic (8.71e-3)" "unprognostic (6.43e-2)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 591.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" CFAP298 "C21orf48, C21orf59, CILD26, FBB18, FLJ20467, Kur" ENSG00000159079 "Cilia and flagella associated protein 298" P57076 21 32592079-32612603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 174.8;Muller glia cells: 203.7;Respiratory ciliated cells: 264.6;Spermatocytes: 238.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "HPA018453, HPA019055, HPA028849, CAB034170" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 56: Ciliated cells - Cilium assembly" Cytosol Microtubules "CAB034170: AB_1564311, HPA018453: AB_1845700, HPA019055: AB_1845701, HPA028849: AB_10602111" "unprognostic (9.76e-2)" "unprognostic (2.99e-1)" "unprognostic (2.39e-1)" "prognostic favorable (8.90e-4)" "unprognostic (1.55e-1)" "unprognostic (2.80e-2)" "unprognostic (5.05e-3)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (1.81e-3)" "unprognostic (2.07e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.74e-2)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (4.37e-2)" CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells" "HPA038925, HPA038934" Supported "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 77.2;Microglial cells: 152.3;Prostatic glandular cells: 68.1;Serous glandular cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 37.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 15: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 21: Serous glandular cells - Salivary secretion" "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: AB_2683274, HPA069214: AB_2686102" "unprognostic (1.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.52e-2)" "prognostic favorable (3.55e-4)" "unprognostic (3.22e-1)" "unprognostic (1.51e-3)" "prognostic favorable (5.58e-4)" "unprognostic (4.32e-2)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "prognostic favorable (1.37e-6)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.88e-3)" "unprognostic (1.18e-2)" CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.9;Erythroid cells: 30.4;Extravillous trophoblasts: 37.0;Spermatocytes: 48.9;Spermatogonia: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1407.8;Respiratory ciliated cells: 946.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825, HPA074310" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Plasma membrane" "CAB012991: AB_2533205, HPA042413: AB_2732498, HPA048825: AB_2680533, HPA074310: " "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (7.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.77e-1)" "unprognostic (4.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (1.85e-1)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in all" "Erythroid cells: 115.5;Granulosa cells: 87.4;Spermatocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Supported "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: Non-specific - Nuclear processes" "Cluster 43: Non-specific - Cell proliferation" Microtubules "Mitotic spindle, Centrosome" "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1325.5;Intestinal goblet cells: 775.6;Paneth cells: 891.5;Proximal enterocytes: 1352.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.8;Club cells: 39.0;Gastric mucus-secreting cells: 32.8;Ionocytes: 24.3;Mucus glandular cells: 22.9;Respiratory ciliated cells: 75.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.5;lung cancer: 2.9" "Heart muscle - Cardiomyocytes, Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" CLINT1 "CLINT, ENTH, EPNR, KIAA0171" ENSG00000113282 "Clathrin interactor 1" Q14677 5 157785743-157859145 "Plasma proteins, Predicted intracellular proteins, Transporters" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 749.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 749.5" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043280, HPA056947" Supported Supported Nucleoplasm,Vesicles NA NA 540000 "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 57: Non-specific - Translation" "Cluster 40: Plasma cells - Humoral immune response" Vesicles Nucleoplasm "HPA043280: AB_10793944, HPA056947: AB_2683283" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "prognostic favorable (2.95e-4)" "unprognostic (7.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (2.53e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.56e-1)" CMTM2 "CKLFSF2, FLJ25732, MGC39436" ENSG00000140932 "CKLF like MARVEL transmembrane domain containing 2" Q8TAZ6 16 66579448-66588275 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 429 "testis: 648.9" "Group enriched" "Detected in some" 56 "Early spermatids: 3421.7;Late spermatids: 3443.2;Spermatocytes: 1129.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Low cancer specificity" "Detected in single" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Stomach - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 36: Testis - Spermatogenesis" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "unprognostic (2.81e-1)" "unprognostic (3.75e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (8.71e-2)" "unprognostic (3.31e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-2)" "unprognostic (3.27e-2)" "unprognostic (1.02e-4)" "unprognostic (1.80e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.2" "Cell type enhanced" "Detected in many" "Ionocytes: 50.5;Respiratory ciliated cells: 41.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Cytosol "HPA030847: AB_10601100" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-2)" "unprognostic (5.26e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-1)" "unprognostic (2.49e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-2)" "unprognostic (3.27e-2)" "unprognostic (2.91e-1)" "prognostic favorable (5.91e-4)" CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 96.5;Distal enterocytes: 65.3;Rod photoreceptor cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 65: Breast cancer - Unknown function" "Cluster 50: Enterocytes - Absorption" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" COLCA2 "C11orf93, CASC13" ENSG00000214290 "Colorectal cancer associated 2" A8K830 11 111298555-111308735 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.6;Cholangiocytes: 28.9;Early spermatids: 48.8;Ionocytes: 25.4;Late spermatids: 82.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 5: Bronchus - Unknown function" "unprognostic (2.73e-3)" "unprognostic (5.15e-2)" "unprognostic (6.97e-3)" "unprognostic (1.30e-3)" "unprognostic (1.15e-1)" "unprognostic (9.04e-2)" "unprognostic (1.13e-3)" "unprognostic (3.28e-2)" "unprognostic (6.03e-3)" "unprognostic (3.54e-2)" "unprognostic (3.34e-2)" "unprognostic (1.90e-1)" "prognostic favorable (8.97e-6)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.05e-2)" "unprognostic (2.46e-1)" COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: AB_1847105" "unprognostic (1.56e-2)" "unprognostic (4.75e-3)" "unprognostic (7.57e-2)" "unprognostic (4.40e-3)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-3)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "prognostic favorable (8.54e-4)" "unprognostic (4.94e-2)" "unprognostic (2.40e-1)" "unprognostic (6.08e-3)" "unprognostic (7.24e-2)" "unprognostic (1.71e-1)" "unprognostic (7.31e-3)" "unprognostic (1.88e-1)" CPXM1 "CPX-1, CPX1, CPXM" ENSG00000088882 "Carboxypeptidase X, M14 family member 1" Q96SM3 20 2794074-2800627 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 145.5;Fibroblasts: 40.6;Theca cells: 53.3;Thymic epithelial cells: 77.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 6.9" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Leukemia: 44.5;Neuroblastoma: 78.2" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "Secreted in other tissues" NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: RS4;11 - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" "unprognostic (7.48e-2)" "unprognostic (3.61e-1)" "unprognostic (6.70e-2)" "unprognostic (1.47e-2)" "unprognostic (3.41e-1)" "unprognostic (5.24e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (9.32e-2)" "unprognostic (7.02e-2)" "unprognostic (3.23e-2)" "prognostic unfavorable (4.62e-10)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (5.55e-3)" "unprognostic (1.27e-2)" CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 145.3;Exocrine glandular cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 20 "B-cells: 3.1;T-cells: 9.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 499.4;Kupffer cells: 270.2;Macrophages: 260.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Cell type enhanced" "Detected in some" "dendritic cells: 3.7;granulocytes: 17.2;Langerhans cells: 9.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Cancer enhanced" "Detected in some" "Leukemia: 7.6;Myeloma: 5.6" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Mast cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA075272 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" "HPA075272: " "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 120.3;Basal prostatic cells: 68.6;Horizontal cells: 28.2;Inhibitory neurons: 62.4;Oligodendrocyte precursor cells: 52.5" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.6" "Colon - Enteric glia cells, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 41: Alveolar cells - Lung function" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "esophagus: 11304.7" "Cell type enriched" "Detected in all" 4 "Suprabasal keratinocytes: 27723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 8700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Nucleoli "CAB047320: , HPA017380: AB_1847414, HPA058557: AB_2683755" "unprognostic (1.69e-1)" "unprognostic (3.35e-1)" "unprognostic (2.09e-1)" "unprognostic (3.05e-2)" "unprognostic (3.05e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (6.66e-5)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (3.63e-1)" "unprognostic (4.88e-1)" "unprognostic (4.24e-2)" "unprognostic (1.24e-1)" CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2308.8;Excitatory neurons: 1236.3;Inhibitory neurons: 1097.8;Oligodendrocyte precursor cells: 1357.9;Oligodendrocytes: 409.5" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.1" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2520.2;Kupffer cells: 1044.3;Macrophages: 1561.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 69: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 3579.4;Macrophages: 1413.3;Proximal enterocytes: 1613.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Lung - Macrophages" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 68: Kidney - Mixed function" "Cluster 19: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 997.8;Langerhans cells: 1157.0;Macrophages: 773.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 19: Macrophages - Innate immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" CTXND1 LINC01314 ENSG00000259417 "Cortexin domain containing 1" A0A1B0GTU2 15 80195481-80252213 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 30.9;liver: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 36.1;Cholangiocytes: 19.2;Hepatocytes: 17.2;Inhibitory neurons: 47.2;Melanocytes: 24.4;Oligodendrocyte precursor cells: 58.7" "Group enriched" "Detected in many" 7 "glioma: 3.4;liver cancer: 2.7;melanoma: 9.1;thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Rhabdoid: 5.9;skin cancer: 3.7" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Region enriched" "Detected in all" 4 "hippocampal formation: 35.0" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 32: Neurons - Synaptic function" "unprognostic (4.15e-5)" "unprognostic (8.42e-2)" "unprognostic (6.08e-2)" "unprognostic (1.86e-3)" "unprognostic (5.59e-2)" "unprognostic (3.48e-1)" "unprognostic (1.90e-2)" "unprognostic (2.61e-1)" "unprognostic (2.41e-1)" "unprognostic (7.04e-2)" "unprognostic (3.90e-4)" "unprognostic (2.43e-1)" "unprognostic (1.72e-2)" "unprognostic (1.92e-3)" "unprognostic (1.06e-1)" "unprognostic (5.14e-3)" "unprognostic (1.34e-1)" CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.6;Basal squamous epithelial cells: 1379.7;Breast myoepithelial cells: 1749.0;Fibroblasts: 1472.7;Glandular and luminal cells: 1617.8;Proximal tubular cells: 3452.0;Suprabasal keratinocytes: 1279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 170.2;head and neck cancer: 230.8" "Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: DU4475 - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;intestine: 6.4;lymphoid tissue: 16.3" "Cell type enriched" "Detected in some" 8 "dendritic cells: 385.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 306.7" "Group enriched" "Detected in many" 5 "dendritic cells: 306.7;NK-cells: 198.9;T-cells: 124.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 1.6;Leukemia: 1.5;lymphoma: 5.9;Myeloma: 4.3" "Adipose subcutaneous - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 88.1;T-cells: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 445.8" "Lineage enriched" "Detected in many" 5 "T-cells: 445.8" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0" "Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" CYB5R4 "b5+b5R, dJ676J13.1, NCB5OR" ENSG00000065615 "Cytochrome b5 reductase 4" Q7L1T6 6 83859656-83967423 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 157.7;Late spermatids: 380.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 199.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018992 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 6: Late spermatids - Spermatogenesis" "HPA018992: AB_1847371" "unprognostic (4.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-2)" "unprognostic (1.72e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (4.77e-1)" "unprognostic (6.77e-2)" "unprognostic (1.39e-2)" "unprognostic (5.44e-1)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.15e-1)" "unprognostic (8.15e-2)" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 367.9;Hofbauer cells: 149.1;Proximal enterocytes: 197.5" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cancer enhanced" "Detected in many" "liver cancer: 32.5;skin cancer: 61.9" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 19: Macrophages - Innate immune response" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 110.7;Cytotrophoblasts: 116.1;Oligodendrocytes: 64.6;Proximal enterocytes: 118.1;Syncytiotrophoblasts: 255.4" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 254.6;Hepatocytes: 104.3;Late spermatids: 96.6;Spermatocytes: 56.7;Spermatogonia: 47.2" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 49: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" DLEU7 FLJ44882 ENSG00000186047 "Deleted in lymphocytic leukemia 7" Q6UYE1 13 50519364-50843939 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 5.0;choroid plexus: 2.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 25.7;Excitatory neurons: 26.5;Inhibitory neurons: 43.9;Macrophages: 10.7;Microglial cells: 34.7;Oligodendrocyte precursor cells: 20.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Lung - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA053750 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" "HPA053750: AB_2682249" "unprognostic (3.97e-2)" "unprognostic (2.53e-1)" "unprognostic (7.03e-2)" "unprognostic (9.31e-2)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (4.47e-3)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (8.75e-3)" "unprognostic (1.23e-1)" "unprognostic (1.69e-1)" "unprognostic (5.88e-2)" "unprognostic (1.59e-1)" "unprognostic (4.52e-2)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" DNAJC5B "CSP-beta, MGC26226" ENSG00000147570 "DnaJ heat shock protein family (Hsp40) member C5 beta" Q9UF47 8 66021553-66101245 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 65.4" "Group enriched" "Detected in some" 131 "Early spermatids: 767.4;Late spermatids: 2900.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 5.7" "Lineage enriched" "Detected in many" 5 "B-cells: 5.7" "Group enriched" "Detected in some" 11 "Leukemia: 1.7;lymphoma: 6.2;Myeloma: 3.2;Rhabdoid: 5.1" "Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" "unprognostic (1.01e-1)" "unprognostic (7.29e-3)" "unprognostic (7.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.76e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (7.78e-2)" "unprognostic (2.53e-3)" "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (8.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.80e-1)" "unprognostic (4.42e-2)" "unprognostic (1.88e-1)" "unprognostic (8.84e-2)" DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 319.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 110.0;Cone photoreceptor cells: 106.8;Excitatory neurons: 173.6;Horizontal cells: 165.3;Inhibitory neurons: 178.2;Rod photoreceptor cells: 126.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 319.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910" Enhanced NA NA 8800 "Cluster 10: Brain - Neuronal signaling" "Cluster 68: Kidney - Mixed function" "Cluster 37: Neurons - Neuronal signaling" "CAB005920: , HPA049910: AB_2680948" "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 107.2;Excitatory neurons: 48.9;Horizontal cells: 34.6;Inhibitory neurons: 77.7;Muller glia cells: 57.0;Oligodendrocyte precursor cells: 55.8" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.6" "Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" EDEM1 "EDEM, KIAA0212" ENSG00000134109 "ER degradation enhancing alpha-mannosidase like protein 1" Q92611 3 5187646-5219958 "Plasma proteins, Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 79.1" "Cell type enhanced" "Detected in many" "dendritic cells: 115.1;Langerhans cells: 231.5;Plasma cells: 136.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029565 Uncertain Enhanced "Endoplasmic reticulum,Aggresome" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "Endoplasmic reticulum" Aggresome "HPA029565: AB_10602032" "unprognostic (3.03e-1)" "unprognostic (3.02e-2)" "unprognostic (3.57e-3)" "unprognostic (4.30e-3)" "unprognostic (1.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.29e-2)" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (5.72e-3)" "unprognostic (1.51e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "unprognostic (2.34e-2)" "unprognostic (1.37e-1)" "unprognostic (3.09e-1)" EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 287.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 518.7;Basal respiratory cells: 394.5;Club cells: 415.3;Glandular and luminal cells: 411.1;Mucus glandular cells: 530.1;Salivary duct cells: 463.9;Squamous epithelial cells: 392.3;Suprabasal keratinocytes: 389.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "Golgi apparatus" "HPA050923: AB_2681275, HPA060734: AB_2684351" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.38e-1)" "unprognostic (6.79e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (7.08e-2)" ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.3;Gastric mucus-secreting cells: 4.2;Proximal enterocytes: 5.6;Squamous epithelial cells: 20.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cancer enriched" "Detected in many" 7 "lymphoma: 61.6" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044305 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 52.5;placenta: 35.3;retina: 27.9" "Cell type enhanced" "Detected in many" "Astrocytes: 92.0;Cone photoreceptor cells: 51.7;Extravillous trophoblasts: 22.2;Spermatocytes: 22.0" "Group enriched" "Detected in many" 8 "breast cancer: 11.9;glioma: 25.8;liver cancer: 24.0;melanoma: 14.2;prostate cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 27.0" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 63: Astrocytes - Nervous system maintenance" "prognostic favorable (6.73e-5)" "unprognostic (4.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-5)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.89e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (6.92e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-12)" "unprognostic (9.98e-4)" "unprognostic (8.86e-2)" "unprognostic (3.41e-1)" "unprognostic (9.47e-2)" EML5 "EMAP-2, FAP16, HuEMAP-2" ENSG00000165521 "EMAP like 5" Q05BV3 14 88612431-88792752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7;ovary: 17.4;retina: 9.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 78.3;Granulosa cells: 92.1;Inhibitory neurons: 104.2;Oligodendrocyte precursor cells: 93.9;Prostatic glandular cells: 44.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 17.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 15 "Neuroblastoma: 33.8" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 41.5" "HPA054019, HPA055379" Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" "HPA054019: AB_2682345, HPA055379: AB_2682799" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (2.49e-1)" "unprognostic (8.68e-2)" "unprognostic (1.15e-1)" "unprognostic (4.67e-4)" "unprognostic (3.42e-2)" "unprognostic (4.50e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.36e-1)" "unprognostic (1.11e-4)" "unprognostic (1.21e-2)" "unprognostic (1.05e-1)" "unprognostic (3.82e-1)" "unprognostic (1.53e-3)" EML6 FLJ42562 ENSG00000214595 "EMAP like 6" Q6ZMW3 2 54723499-54972025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.3;retina: 13.9" "Cell type enhanced" "Detected in many" "Astrocytes: 140.4;Excitatory neurons: 367.6;Inhibitory neurons: 259.0;Oligodendrocyte precursor cells: 91.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 14.1;Neuroblastoma: 8.0" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062808, HPA068759" Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" Mitochondria Vesicles "HPA062808: AB_2684872, HPA068759: AB_2686027" "unprognostic (1.06e-1)" "unprognostic (6.89e-4)" "unprognostic (7.83e-2)" "unprognostic (9.96e-2)" "unprognostic (6.24e-2)" "unprognostic (3.26e-4)" "unprognostic (5.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (6.27e-2)" "unprognostic (6.85e-6)" "unprognostic (5.00e-1)" "unprognostic (5.81e-2)" "unprognostic (6.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (5.13e-3)" ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 246.4;Endometrial ciliated cells: 137.5;Glandular and luminal cells: 373.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Cancer enhanced" "Detected in some" "Bone cancer: 4.4;Leukemia: 6.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mast cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" EPX "EPO, EPP, EPX-PEN" ENSG00000121053 "Eosinophil peroxidase" P11678 17 58192726-58205174 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "bone marrow: 33.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.5;Inhibitory neurons: 1.1;Oligodendrocyte precursor cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cancer enriched" "Detected in some" 5 "lymphoma: 23.9" "Lung - Neutrophil_1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076792 Enhanced NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 71: Erythroid cells - Oxygen transport" "HPA076792: " "unprognostic (5.67e-2)" "unprognostic (1.73e-2)" "unprognostic (3.36e-2)" "unprognostic (3.30e-1)" "unprognostic (2.18e-1)" "unprognostic (1.34e-3)" "unprognostic (4.83e-1)" "unprognostic (3.16e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-2)" "unprognostic (1.71e-4)" "unprognostic (7.38e-2)" "unprognostic (1.64e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.02e-2)" "unprognostic (1.73e-1)" ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in all" 5 "breast cancer: 837.2;Esophageal cancer: 442.3;Gastric cancer: 212.0" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 5: Bronchus - Unknown function" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 87.1;Endothelial cells: 103.9;granulocytes: 26.0;Microglial cells: 85.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Leukemia: 24.7;prostate cancer: 23.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 385.2;Endothelial cells: 271.5;Sertoli cells: 63.6;Smooth muscle cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 15.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 89.9;Intestinal goblet cells: 92.8;Suprabasal keratinocytes: 94.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 26: Intestinal epithelial cells - Absorption" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 70.0" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.1" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 680.9;Basal respiratory cells: 349.4;Club cells: 393.3;Exocrine glandular cells: 480.8;Ionocytes: 314.5;Peritubular cells: 515.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "head and neck cancer: 689.5" "Kidney - Podocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489193 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 73.4;Excitatory neurons: 108.6;Inhibitory neurons: 128.1;Oligodendrocyte precursor cells: 105.9;Oligodendrocytes: 99.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 16.7" "Lineage enriched" "Detected in many" 9 "T-cells: 16.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favorable (2.66e-4)" "prognostic favorable (6.83e-5)" FAIM2 "KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2" ENSG00000135472 "Fas apoptotic inhibitory molecule 2" Q9BWQ8 12 49866896-49904217 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 359.4;parathyroid gland: 98.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 118.5;Early spermatids: 246.7;Excitatory neurons: 76.5;Horizontal cells: 160.2;Inhibitory neurons: 102.5;Oligodendrocytes: 52.4" "Cancer enriched" "Detected in many" 8 "glioma: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.9" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 33.6" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018790, HPA048800" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "Intermediate filaments" "HPA018790: AB_1852822, HPA048800: AB_2680526" "unprognostic (1.74e-1)" "unprognostic (5.98e-4)" "unprognostic (2.22e-1)" "unprognostic (9.75e-3)" "unprognostic (3.36e-2)" "unprognostic (2.61e-4)" "unprognostic (2.62e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (1.75e-2)" "unprognostic (5.66e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-6)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.47e-1)" "unprognostic (6.78e-4)" FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35044907-35113130 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 761.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 46: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" Vesicles Nucleoplasm "HPA053222: AB_2682083, HPA055440: AB_2682817" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (4.64e-3)" "unprognostic (6.28e-2)" "unprognostic (7.79e-2)" "prognostic favorable (8.51e-5)" "unprognostic (1.12e-2)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (8.28e-2)" "unprognostic (1.91e-1)" FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 8 "Early spermatids: 199.5;Late spermatids: 140.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 52: Spermatids - Smell perception" "Cluster 49: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" FAM229B "C6orf225, DKFZp586F0922, LOC619208" ENSG00000203778 "Family with sequence similarity 229 member B" Q4G0N7 6 112087591-112102790 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 448.1" "Group enriched" "Detected in many" 9 "Early spermatids: 2952.3;Late spermatids: 7719.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA036068 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 15: Non-specific - Protein binding" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA036068: AB_10673495" "unprognostic (1.65e-1)" "unprognostic (9.41e-2)" "unprognostic (4.29e-2)" "unprognostic (4.67e-3)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (2.71e-2)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-3)" "unprognostic (4.74e-2)" "prognostic favorable (8.76e-4)" "unprognostic (3.74e-3)" "unprognostic (1.36e-1)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" FAM43B FLJ44952 ENSG00000183114 "Family with sequence similarity 43 member B" Q6ZT52 1 20552573-20555020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 21.0;brain: 21.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Excitatory neurons: 2.5;Fibroblasts: 3.8;Horizontal cells: 3.8;Inhibitory neurons: 7.3" "Cancer enhanced" "Detected in some" "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.1;cervical cancer: 2.6;Rhabdoid: 3.4" "Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050813 Approved Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: Bone cancer - Transcription" "Cluster 65: Fibroblasts - ECM organization" Cytosol "HPA050813: AB_2681244" "unprognostic (1.51e-1)" "unprognostic (5.85e-2)" "unprognostic (2.80e-3)" "unprognostic (1.48e-1)" "unprognostic (5.97e-3)" "unprognostic (1.74e-1)" "unprognostic (8.33e-2)" "unprognostic (5.87e-4)" "unprognostic (1.86e-2)" "unprognostic (7.46e-2)" "unprognostic (8.85e-3)" "unprognostic (2.73e-1)" "unprognostic (1.78e-4)" "unprognostic (1.06e-2)" "unprognostic (6.05e-3)" "unprognostic (6.48e-2)" "unprognostic (2.12e-2)" FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Basal squamous epithelial cells: 40.5;Squamous epithelial cells: 35.5;Suprabasal keratinocytes: 49.9;Syncytiotrophoblasts: 26.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.3" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.8;Enteroendocrine cells: 54.8;Gastric mucus-secreting cells: 127.6;Intestinal goblet cells: 162.1;Paneth cells: 66.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.7;Gastric cancer: 11.6" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.0;Spermatogonia: 30.4;Syncytiotrophoblasts: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: Non-specific - Unknown function" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.0;Spermatocytes: 63.3;Spermatogonia: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 6: BEWO - Unknown function" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.7;Fibroblasts: 429.8;Inhibitory neurons: 120.7;Leydig cells: 240.1;Oligodendrocytes: 206.4;Peritubular cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 81.0;thyroid cancer: 77.9" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Group enriched" "Detected in many" 6 "Hofbauer cells: 243.9;Kupffer cells: 232.2;Macrophages: 324.9;monocytes: 901.8;NK-cells: 607.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Cell type enriched" "Detected in many" 9 "NK-cells: 1206.6" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Group enriched" "Detected in some" 17 "Rhabdoid: 70.9;skin cancer: 23.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Lacrimo-auriculo-dento-digital syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 221.1;Cholangiocytes: 192.5;Oligodendrocytes: 531.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 215.7" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: NCI-H716 - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.5;lung: 65.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.6;Hepatocytes: 23.6;Theca cells: 30.1;Undifferentiated cells: 35.4" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 102.2" "Liver - Hepatocytes, Lung - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 7400000 "Cluster 18: Non-specific - Mitochondria" "Cluster 35: Liver cancer - Metabolism" "Cluster 11: Non-specific - Transcription" "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 101.2;Cone photoreceptor cells: 74.1;Excitatory neurons: 130.2;Granulosa cells: 84.1;Inhibitory neurons: 182.6;Oligodendrocyte precursor cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 37: Neurons - Neuronal signaling" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 62.6;Endothelial cells: 81.0;Kupffer cells: 94.4;Macrophages: 57.9;Microglial cells: 225.3;monocytes: 83.6;NK-cells: 75.3;T-cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.1;Myeloma: 20.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 414.8;Skeletal myocytes: 263.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 97.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Approved "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 77: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 270.8;Excitatory neurons: 542.5;Inhibitory neurons: 313.2;Leydig cells: 214.3;Microglial cells: 421.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 23.8" "Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22580998-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 36.2;pancreas: 26.6;stomach 1: 31.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 47.8;Alveolar cells type 2: 54.8;Cholangiocytes: 52.0;Endometrial ciliated cells: 30.6;Enteroendocrine cells: 30.5;Exocrine glandular cells: 34.6;Gastric mucus-secreting cells: 40.5;Hepatocytes: 60.9;Intestinal goblet cells: 58.9;Undifferentiated cells: 30.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 18.2" "Colon - Colon enterocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "midbrain: 3.9" "CAB001388, HPA066846" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 26: Intestinal epithelial cells - Absorption" "Nucleoplasm, Cell Junctions" "CAB001388: AB_2262810, HPA066846: AB_2685736" "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "prognostic favorable (7.57e-6)" "unprognostic (6.82e-2)" "unprognostic (1.50e-6)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "prognostic favorable (6.28e-4)" "prognostic favorable (2.34e-4)" "unprognostic (3.18e-1)" "unprognostic (2.55e-15)" "unprognostic (2.50e-2)" "unprognostic (1.68e-1)" "unprognostic (7.12e-2)" "unprognostic (3.93e-3)" FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86566829-86569728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 10.5;Peritubular cells: 29.2;Salivary duct cells: 18.8;Smooth muscle cells: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 14.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 42.7" HPA056302 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA056302: AB_2683093" "unprognostic (3.17e-2)" "unprognostic (1.76e-3)" "unprognostic (4.87e-2)" "unprognostic (4.32e-1)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (4.49e-2)" "unprognostic (1.15e-2)" "unprognostic (4.71e-2)" "unprognostic (8.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.57e-7)" "unprognostic (1.12e-2)" "unprognostic (3.47e-2)" "unprognostic (2.43e-1)" "unprognostic (1.84e-4)" FOXL1 "FKH6, FKHL11, FREAC7" ENSG00000176678 "Forkhead box L1" Q12952 16 86576368-86583478 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Pancreatic endocrine cells: 1.7;Peritubular cells: 10.6;Sertoli cells: 2.8;Smooth muscle cells: 4.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "spinal cord: 5.0" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (3.21e-1)" "unprognostic (3.31e-3)" "unprognostic (2.98e-1)" "unprognostic (1.12e-2)" "unprognostic (3.79e-1)" "unprognostic (4.62e-2)" "unprognostic (1.43e-3)" "unprognostic (1.79e-2)" "unprognostic (1.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.33e-3)" "unprognostic (1.35e-1)" "unprognostic (2.36e-8)" "unprognostic (1.50e-1)" "unprognostic (9.77e-2)" "unprognostic (3.16e-2)" "unprognostic (5.17e-3)" FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enriched" "Detected in some" 9 "monocytes: 410.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.7;Leukemia: 2.7;liver cancer: 2.2" "Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Neutrophils" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.3" "Cancer enriched" "Detected in all" 4 "testis cancer: 70.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.2" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Mitochondria "HPA049763: AB_2680868" "unprognostic (4.93e-2)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (4.04e-3)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.17e-3)" "unprognostic (2.60e-1)" "unprognostic (8.02e-2)" "unprognostic (4.60e-2)" "unprognostic (3.25e-2)" "prognostic favorable (2.55e-4)" "unprognostic (7.87e-3)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.08e-2)" FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.7;thyroid gland: 4.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 18.5;Astrocytes: 44.6;Cholangiocytes: 15.4;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 42.9;Proximal tubular cells: 19.8;Skeletal myocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 29.7" "Lung - Alveolar cells type 2, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA028831 Uncertain Approved Cytosol NA NA 1500000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: Skin cancer - Membrane components" "Cluster 14: Endometrium - Transcription regulation" Cytosol "HPA028831: AB_10603668" "unprognostic (1.71e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-1)" "unprognostic (6.24e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.25e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.23e-7)" "unprognostic (7.21e-2)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (3.14e-1)" GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 152.4;Extravillous trophoblasts: 164.1;Syncytiotrophoblasts: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.8;intermediate monocyte: 50.3;myeloid DC: 39.7;neutrophil: 27.0;non-classical monocyte: 68.5" "Group enriched" "Detected in all" 10 "dendritic cells: 39.7;granulocytes: 27.0;monocytes: 68.5" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3800000 "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: Myeloma - Humoral immune response" "Cluster 19: Macrophages - Innate immune response" Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 131.6;Oligodendrocytes: 154.2;Schwann cells: 262.9" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cancer enriched" "Detected in many" 5 "skin cancer: 129.1" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" GAS8 "DRC4, GAS11" ENSG00000141013 "Growth arrest specific 8" O95995 16 90019629-90044975 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 132.0;Late spermatids: 311.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041311, HPA048238" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: Non-specific - Unknown function" "Cluster 36: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA041311: AB_2677402, HPA048238: AB_2680324" "unprognostic (2.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.73e-1)" "unprognostic (3.91e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (4.47e-1)" "prognostic favorable (7.67e-4)" "unprognostic (3.06e-2)" "prognostic favorable (1.09e-7)" "unprognostic (1.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.19e-2)" GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 81.6;Hepatocytes: 18.0;Microglial cells: 19.2;Oligodendrocyte precursor cells: 21.7;Peritubular cells: 19.1" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.1;Neuroblastoma: 2.1" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Cardiomyocytes: 2.4;Distal tubular cells: 3.1;Excitatory neurons: 1.6;Fibroblasts: 2.2;Oligodendrocyte precursor cells: 6.7;Pancreatic endocrine cells: 1.7;Spermatogonia: 2.2;Thymic epithelial cells: 2.8" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 32.6;testis cancer: 15.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 14: Bone cancer - Transcription" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Group enriched" "Detected in many" 4 "Adipocytes: 65.2;Endothelial cells: 82.1;Kupffer cells: 66.5;Macrophages: 30.7;Microglial cells: 31.9;monocytes: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 1.5;lymphoma: 2.3;Myeloma: 1.2" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.3" "Cell type enhanced" "Detected in all" "Early spermatids: 97.4;Late spermatids: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 36000 "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 65: Breast cancer - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: AB_1078966, HPA004186: AB_1078967" "unprognostic (3.66e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-2)" "unprognostic (6.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.00e-3)" "unprognostic (2.79e-1)" "unprognostic (5.23e-2)" "unprognostic (2.12e-2)" "unprognostic (3.08e-1)" "unprognostic (8.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 27.0" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "cervical cancer: 36.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" GMIP ARHGAP46 ENSG00000089639 "GEM interacting protein" Q9P107 19 19629476-19643657 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.9;lymphoid tissue: 54.3" "Cell type enhanced" "Detected in many" "B-cells: 26.9;Hofbauer cells: 25.5;Kupffer cells: 29.0;Macrophages: 27.5;monocytes: 46.5;T-cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042484, HPA045481" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 2: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042484: AB_2678018, HPA045481: AB_2679343" "unprognostic (7.54e-2)" "unprognostic (5.35e-3)" "unprognostic (3.10e-3)" "unprognostic (4.54e-3)" "unprognostic (1.44e-1)" "unprognostic (1.24e-3)" "unprognostic (1.23e-2)" "unprognostic (4.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.85e-2)" "unprognostic (6.75e-3)" "prognostic unfavorable (3.97e-5)" "prognostic favorable (3.03e-4)" "unprognostic (4.92e-2)" "unprognostic (2.54e-1)" "prognostic favorable (5.15e-4)" GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 288.7;endometrium 1: 71.9;lymphoid tissue: 86.3" "Cell type enriched" "Detected in many" 4 "NK-cells: 8296.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17623.2" "Group enriched" "Detected in all" 63 "NK-cells: 17623.2;T-cells: 7874.6" "Cancer enhanced" "Detected in some" "Leukemia: 3.9;lymphoma: 7.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" NA NA 2920000 17000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 246.3;Cardiomyocytes: 254.1;Fibroblasts: 248.0;Hofbauer cells: 715.1;Macrophages: 348.0;Melanocytes: 947.5" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cancer enriched" "Detected in all" 4 "skin cancer: 688.7" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Macrophages, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;pancreas: 6.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Extravillous trophoblasts: 5.9;Hofbauer cells: 2.9;Respiratory ciliated cells: 2.4;Sertoli cells: 2.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Macrophages, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 20: Airway & Pancreas - Proteolysis" "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "granulocytes: 51.9;Hofbauer cells: 222.8;Kupffer cells: 61.6;Macrophages: 136.6;Microglial cells: 52.9" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 3735.0;Kupffer cells: 2302.2;Macrophages: 1734.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 4: Platelets - Platelet activation" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 53.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in all" "B-cells: 68.8;Late spermatids: 76.2;monocytes: 83.0;NK-cells: 87.5;Plasma cells: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favorable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;parathyroid gland: 4.4" "Group enriched" "Detected in some" 15 "Excitatory neurons: 763.7;Inhibitory neurons: 580.5;Oligodendrocyte precursor cells: 1138.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1448.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 19: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.4;Enteroendocrine cells: 10.1;Extravillous trophoblasts: 7.7;Granulosa cells: 10.2;Hepatocytes: 17.8" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 46.5;liver cancer: 16.8;skin cancer: 29.6;testis cancer: 59.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 98.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cancer enhanced" "Detected in some" "Leukemia: 6.4;liver cancer: 3.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 29: Hepatocytes - Metabolism" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 120.8;Basal respiratory cells: 103.8;Squamous epithelial cells: 27.8;Suprabasal keratinocytes: 92.7" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 180.2" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 187.4;Kupffer cells: 178.4;Langerhans cells: 103.8;Macrophages: 142.2;monocytes: 256.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 5 "Leukemia: 21.9;lymphoma: 31.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 168.9;Hofbauer cells: 166.8;Kupffer cells: 419.9;Macrophages: 339.0;monocytes: 388.0;NK-cells: 186.3;T-cells: 179.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Leukemia: 183.8;lymphoma: 217.7;Myeloma: 213.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 463.3;Hofbauer cells: 320.1;Syncytiotrophoblasts: 515.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 59: Fibroblasts - Metabolism" "Cluster 19: Macrophages - Innate immune response" "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 12 "Early spermatids: 14.1;Hofbauer cells: 36.9;Kupffer cells: 37.9;Macrophages: 32.7;monocytes: 45.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cancer enhanced" "Detected in single" "Leukemia: 3.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.9;Early spermatids: 19.2;Glandular and luminal cells: 12.6;Granulosa cells: 29.8;Smooth muscle cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 18: Non-specific - Mixed function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" HMGCR ENSG00000113161 "3-hydroxy-3-methylglutaryl-CoA reductase" P04035 5 75336329-75364001 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 105.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 236.4;Suprabasal keratinocytes: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008338, CAB016797, CAB078688" Supported NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "CAB016797: , CAB078688: AB_2665607, HPA008338: AB_10960401" "unprognostic (5.07e-2)" "unprognostic (1.65e-2)" "unprognostic (3.65e-3)" "unprognostic (1.02e-2)" "unprognostic (1.65e-3)" "unprognostic (1.02e-1)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "unprognostic (1.90e-2)" "unprognostic (1.41e-1)" "unprognostic (3.99e-2)" "prognostic favorable (9.42e-6)" "unprognostic (2.44e-1)" "unprognostic (2.55e-2)" "unprognostic (3.64e-3)" "unprognostic (4.37e-2)" HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 401.5;Hepatocytes: 446.5;Kupffer cells: 286.3;Suprabasal keratinocytes: 346.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686431-37745105 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.1;pancreas: 33.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 86.6;Collecting duct cells: 47.3;Ductal cells: 42.4;Early spermatids: 36.4;Exocrine glandular cells: 30.5;Glandular and luminal cells: 41.1;Proximal tubular cells: 37.1" "Cancer enhanced" "Detected in many" "renal cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 44.7" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in single" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm Vesicles "CAB068192: AB_2665649, HPA002083: AB_1080232" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (5.29e-3)" "unprognostic (5.29e-2)" "unprognostic (3.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "prognostic favorable (6.00e-4)" "unprognostic (7.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.49e-2)" "prognostic favorable (2.51e-6)" HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 10.8;Endometrial ciliated cells: 10.5;Granulosa cells: 10.7;Squamous epithelial cells: 7.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "medulla oblongata: 16.7;pons: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_2" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 49 "medulla oblongata: 4.9;pons: 3.7;spinal cord: 6.0" HPA053910 Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 56: Neurons - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" HOXC6 "HOX3, HOX3C" ENSG00000197757 "Homeobox C6" P09630 12 53990624-54030823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.1;ovary: 26.2" "Cell type enhanced" "Detected in some" "Distal tubular cells: 12.4;Granulosa cells: 13.3;Leydig cells: 21.0;Melanocytes: 15.7;Peritubular cells: 14.6;Spermatocytes: 39.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 15 "medulla oblongata: 4.1;pons: 4.3;spinal cord: 3.1;white matter: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 40.1" "Lung - Fibroblast_2" "Region enriched" "Detected in single" 14 "pons and medulla: 1.4" "Region enriched" "Detected in single" 32 "spinal cord: 9.7" HPA054981 Supported Nucleoplasm,Cytosol No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm Cytosol "HPA054981: AB_2682662" "unprognostic (3.54e-2)" "unprognostic (9.20e-2)" "unprognostic (1.68e-6)" "unprognostic (3.92e-2)" "unprognostic (1.10e-3)" "unprognostic (5.01e-4)" "unprognostic (5.52e-3)" "unprognostic (3.32e-3)" "unprognostic (2.81e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (3.55e-6)" "unprognostic (8.63e-2)" "unprognostic (5.76e-2)" "unprognostic (1.40e-2)" "unprognostic (4.71e-2)" HOXD1 "HOX4, HOX4G" ENSG00000128645 "Homeobox D1" Q9GZZ0 2 176188668-176190907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.9;epididymis: 7.5" "Cell type enhanced" "Detected in some" "Adipocytes: 16.6;Basal prostatic cells: 19.3;Distal enterocytes: 27.1;Distal tubular cells: 21.8;Enteroendocrine cells: 15.9;Intestinal goblet cells: 26.7;Oligodendrocytes: 26.5;Paneth cells: 19.7;Proximal enterocytes: 21.8;Undifferentiated cells: 28.6" "Cancer enriched" "Detected in many" 5 "ovarian cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 4.5" "Lung - Alveolar cells type 2" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in many" "HPA040062, HPA056900" Enhanced Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "HPA040062: AB_2676826, HPA056900: AB_2683270" "unprognostic (8.78e-2)" "unprognostic (9.97e-2)" "unprognostic (7.11e-3)" "unprognostic (1.06e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-2)" "unprognostic (7.33e-2)" "unprognostic (4.10e-2)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (9.64e-2)" "unprognostic (4.02e-1)" "unprognostic (1.54e-5)" "unprognostic (4.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 247.5;Granulosa cells: 673.5;Muller glia cells: 340.9;Thymic epithelial cells: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" ICA1L "ALS2CR14, ALS2CR15" ENSG00000163596 "Islet cell autoantigen 1 like" Q8NDH6 2 202773150-202871766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 169.2;Inhibitory neurons: 111.5;Oligodendrocyte precursor cells: 89.5;Rod photoreceptor cells: 85.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042507 Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" Mitochondria "HPA042507: AB_10797016" "unprognostic (4.14e-3)" "unprognostic (3.60e-3)" "unprognostic (5.15e-2)" "unprognostic (5.63e-3)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-4)" "unprognostic (1.66e-1)" "unprognostic (9.60e-2)" "unprognostic (4.50e-4)" "unprognostic (4.15e-1)" "unprognostic (8.15e-3)" "unprognostic (2.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.58e-3)" ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 146.4;Hepatocytes: 177.1;monocytes: 254.2;NK-cells: 246.5;Plasma cells: 138.3;T-cells: 179.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Group enriched" "Detected in all" 6 "Leukemia: 98.4;lymphoma: 73.3;Myeloma: 127.4" "Adipose subcutaneous - T-cells, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Lung - Neutrophil_2, Prostate - T-cells" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 574.8;Cytotrophoblasts: 749.3;Distal tubular cells: 945.4;Extravillous trophoblasts: 657.6;Syncytiotrophoblasts: 615.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Mitotic cells (Lung), Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049119 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved NA NA 28000 "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 29: Hepatocytes - Metabolism" "HPA039169: AB_10674280" "unprognostic (1.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.58e-2)" "unprognostic (1.97e-1)" "unprognostic (5.72e-3)" "unprognostic (1.27e-1)" "unprognostic (1.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.46e-4)" "unprognostic (9.63e-2)" "unprognostic (2.01e-2)" "unprognostic (2.19e-3)" "unprognostic (2.61e-2)" IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 208.4;Kupffer cells: 151.9;Langerhans cells: 137.9;Macrophages: 249.0;monocytes: 224.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" IFT81 "CDV-1R, CDV1, MGC4027" ENSG00000122970 "Intraflagellar transport 81" Q8WYA0 12 110124335-110218793 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 88.1;Respiratory ciliated cells: 72.3;Spermatocytes: 180.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019087, HPA020051" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" "Centrosome, Cytosol" "HPA019087: AB_1851462, HPA020051: AB_1851465" "unprognostic (2.54e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "unprognostic (9.79e-2)" "unprognostic (1.10e-1)" "unprognostic (7.95e-2)" "unprognostic (3.91e-1)" "unprognostic (3.21e-1)" "unprognostic (1.40e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-3)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (1.88e-1)" "unprognostic (2.45e-1)" IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 538.2;Fibroblasts: 1434.1;Leydig cells: 997.0;Peritubular cells: 1559.1;Sertoli cells: 500.3;Smooth muscle cells: 554.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" IGHD3-9 "DXP1, IGHD39" ENSG00000211924 "Immunoglobulin heavy diversity 3-9" 14 105904681-105904711 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.9;stomach 1: 4.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 214 "memory B-cell: 8.9;naive B-cell: 33.8" "Lineage enriched" "Detected in single" 339 "B-cells: 33.8" "Cancer enriched" "Detected in single" 10 "Leukemia: 6.9" "Breast - Plasma cells, Lung - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "unprognostic (1.74e-1)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Cell type enhanced" "Detected in some" "B-cells: 429.3;Basal keratinocytes: 123.6;Plasma cells: 568.0;T-cells: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Group enriched" "Detected in some" 38 "lymphoma: 133.9;Myeloma: 34.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" IGHV1OR21-1 IGHV1/OR21-1 ENSG00000277282 "Immunoglobulin heavy variable 1/OR21-1 (non-functional)" 21 10649400-10649835 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 6.3;stomach 1: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "memory B-cell: 2.0;naive B-cell: 1.7" "Lineage enriched" "Detected in single" 15 "B-cells: 2.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (3.93e-3)" "unprognostic (2.55e-2)" "unprognostic (1.28e-2)" "unprognostic (8.48e-5)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (3.32e-1)" IGHV3OR15-7 IGHV3/OR15-7 ENSG00000259490 "Immunoglobulin heavy variable 3/OR15-7 (pseudogene)" 15 19987656-19988117 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.0;stomach 1: 1.8" "Cell type enriched" "Detected in some" 5 "Plasma cells: 5.1" "Cancer enhanced" "Detected in many" "lung cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.43e-5)" "unprognostic (4.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-4)" "unprognostic (7.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.50e-1)" "unprognostic (1.24e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 913 "Plasma cells: 4001.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cancer enriched" "Detected in single" 33 "Myeloma: 22.0" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;intestine: 3.4;lymphoid tissue: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Cancer enriched" "Detected in single" 23 "lymphoma: 2.2" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" NA NA 32000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.6;lymphoid tissue: 9.5" "Cell type enriched" "Detected in single" 9 "Plasma cells: 3.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Cancer enriched" "Detected in single" 13 "Myeloma: 4.2" "Breast - Plasma cells, Lung - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1100000000 "Cluster 37: B-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 51: Myeloma - Humoral immune response" "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 91 "Plasma cells: 843.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 36 "Leukemia: 236.9;lymphoma: 904.2" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 5 "B-cells: 2.8;Plasma cells: 8.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 11 "Plasma cells: 36.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cancer enhanced" "Detected in single" "Myeloma: 1.2" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 188.3;Late spermatids: 42.1;Microglial cells: 60.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 13.6;Rhabdoid: 6.6" "Colon - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 36.8;Peritubular cells: 13.4;Sertoli cells: 19.3;Skeletal myocytes: 7.9;Smooth muscle cells: 8.0;Theca cells: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cancer enriched" "Detected in some" 12 "Brain cancer: 13.8" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 26.4;skin 1: 37.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.4;Endometrial ciliated cells: 105.4;Glandular and luminal cells: 72.8;Muller glia cells: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.8" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" Cytosol "CAB024990: , HPA042281: AB_10806235" "unprognostic (3.75e-2)" "unprognostic (8.23e-2)" "unprognostic (1.96e-2)" "prognostic favorable (1.43e-6)" "unprognostic (1.57e-2)" "prognostic favorable (2.29e-5)" "unprognostic (9.87e-3)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (8.03e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-6)" "unprognostic (9.38e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-3)" "unprognostic (1.64e-3)" INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 123.2;thyroid gland: 204.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 17.7;Distal enterocytes: 30.6;Inhibitory neurons: 19.2;Muller glia cells: 22.1;Paneth cells: 17.2;Proximal enterocytes: 60.9" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.7" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 65: Breast cancer - Unknown function" "Cluster 50: Enterocytes - Absorption" Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" IQCA1 "DRC11, FLJ22527, IQCA" ENSG00000132321 "IQ motif containing with AAA domain 1" Q86XH1 2 236324147-236507535 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;choroid plexus: 22.7;thyroid gland: 19.2" "Cell type enhanced" "Detected in many" "Astrocytes: 175.2;Endometrial ciliated cells: 57.6;Respiratory ciliated cells: 73.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.3" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.2" HPA057320 Uncertain Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA057320: " "unprognostic (1.73e-2)" "unprognostic (6.38e-2)" "unprognostic (3.75e-3)" "unprognostic (1.62e-2)" "unprognostic (6.27e-3)" "unprognostic (1.73e-2)" "unprognostic (3.23e-5)" "unprognostic (1.55e-1)" "unprognostic (7.23e-3)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.62e-1)" "prognostic favorable (2.54e-4)" "unprognostic (1.19e-3)" "unprognostic (1.67e-3)" "unprognostic (1.91e-3)" "unprognostic (5.30e-2)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 169.2;Early spermatids: 44.6;Peritubular cells: 86.8;Sertoli cells: 35.9;Smooth muscle cells: 100.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.8;Alveolar cells type 2: 101.5;Basal respiratory cells: 120.6;Collecting duct cells: 72.9;Ductal cells: 64.0;Exocrine glandular cells: 185.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 78.0;Gastric mucus-secreting cells: 116.3;Late spermatids: 235.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.9;Hofbauer cells: 80.3;Horizontal cells: 80.8;Melanocytes: 95.8;monocytes: 203.1;NK-cells: 81.9" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 139.3;lymphoma: 102.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 196.1;parathyroid gland: 269.2;thyroid gland: 139.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 29.5;Cholangiocytes: 46.2;Collecting duct cells: 198.9;Distal tubular cells: 43.5;Oligodendrocyte precursor cells: 52.5;Proximal tubular cells: 88.3" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 28.8;Sarcoma: 17.3" "Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4;kidney: 37.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.9;Cytotrophoblasts: 28.5;Distal enterocytes: 36.2;Proximal enterocytes: 56.4;Salivary duct cells: 35.5;Syncytiotrophoblasts: 41.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 50: Enterocytes - Absorption" Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.8;Bipolar cells: 3.4;Fibroblasts: 6.5;Horizontal cells: 9.6;Skeletal myocytes: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.5" "Kidney - T-cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" KIAA0895 ENSG00000164542 KIAA0895 Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.3" "Cell type enhanced" "Detected in many" "Early spermatids: 76.0;Endometrial ciliated cells: 40.6;Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Stomach - Chief cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: AB_2670571, HPA061066: AB_2684423" "unprognostic (4.94e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-1)" "unprognostic (1.39e-1)" "unprognostic (8.85e-2)" "unprognostic (1.15e-3)" "unprognostic (3.79e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (4.71e-3)" "unprognostic (1.46e-1)" "unprognostic (3.49e-1)" "unprognostic (4.51e-2)" "unprognostic (6.68e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 61.4;Microglial cells: 65.7;Oligodendrocytes: 128.0" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 20.8;skin cancer: 27.6" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" KIAA1841 ENSG00000162929 KIAA1841 Q6NSI8 2 61065871-61138034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 11.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 44.8;Excitatory neurons: 89.9;Inhibitory neurons: 76.8;Oligodendrocytes: 60.2;Rod photoreceptor cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051240 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "HPA051240: AB_2681401" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.18e-2)" "unprognostic (5.71e-8)" "unprognostic (1.13e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (6.09e-2)" "unprognostic (8.92e-2)" "unprognostic (7.85e-6)" "unprognostic (8.54e-2)" "unprognostic (1.04e-2)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" KIF27 DKFZp434D0917 ENSG00000165115 "Kinesin family member 27" Q86VH2 9 83834099-83921465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 23.8;testis: 26.2" "Cell type enhanced" "Detected in many" "Early spermatids: 146.8;Endometrial ciliated cells: 75.7;Late spermatids: 89.1;Respiratory ciliated cells: 53.1;Spermatocytes: 58.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.1" "Lineage enriched" "Detected in many" 9 "granulocytes: 16.1" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 55: Non-specific - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "unprognostic (9.75e-2)" "unprognostic (3.86e-2)" "unprognostic (1.46e-1)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (2.83e-3)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" "unprognostic (3.86e-3)" "unprognostic (9.81e-2)" "unprognostic (1.94e-1)" "unprognostic (2.55e-1)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (1.85e-1)" "unprognostic (2.01e-1)" KIR2DL1 "47.11, CD158A, cl-42, nkat1, p58.1" ENSG00000125498 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1" P43626 19 54769793-54784322 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.0" "Cell type enriched" "Detected in some" 5 "NK-cells: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - NK-cells (Lung)" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (2.14e-1)" "unprognostic (9.82e-2)" "unprognostic (8.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.93e-1)" "unprognostic (1.55e-2)" "unprognostic (3.19e-4)" "unprognostic (4.11e-2)" "unprognostic (6.87e-2)" "unprognostic (1.14e-2)" "unprognostic (1.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.61e-2)" KIR2DL3 "CD158B2, cl-6, nkat2, nkat2a, nkat2b, p58" ENSG00000243772 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3" P43628 19 54738513-54753052 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Group enriched" "Detected in some" 35 "NK-cells: 16.6;Pancreatic endocrine cells: 5.2;T-cells: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - NK-cells (Lung)" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (7.37e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-1)" "unprognostic (6.88e-2)" "unprognostic (2.92e-1)" "unprognostic (7.76e-3)" "unprognostic (1.55e-2)" "unprognostic (1.99e-1)" "unprognostic (1.41e-2)" "unprognostic (2.41e-4)" "unprognostic (1.19e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (1.59e-2)" KIR3DL1 "AMB11, CD158E1, CD158e1/2, CD158e2, cl-11, cl-2, KIR, nkat3, NKB1, NKB1B" ENSG00000167633 "Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1" P43629 19 54816468-54830778 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Cell type enriched" "Detected in some" 8 "NK-cells: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Not detected" "Not detected" "Lung - NK-cells (Lung)" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.18e-1)" "unprognostic (8.01e-2)" "unprognostic (3.53e-2)" "unprognostic (4.85e-1)" "unprognostic (5.18e-3)" "unprognostic (6.19e-2)" "unprognostic (4.37e-2)" "unprognostic (9.97e-2)" "unprognostic (1.89e-2)" "unprognostic (3.28e-1)" "unprognostic (7.34e-2)" "unprognostic (2.07e-3)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.73e-1)" "unprognostic (2.19e-2)" KIR3DL2 "CD158K, cl-5, nkat4, nkat4a, nkat4b" ENSG00000240403 "Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2" P43630 19 54850443-54867207 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.9" "Group enriched" "Detected in some" 7 "NK-cells: 38.0;T-cells: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Thyroid - T-cells" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (6.99e-2)" "unprognostic (1.83e-1)" "unprognostic (3.64e-1)" "unprognostic (4.56e-4)" "unprognostic (1.40e-1)" "unprognostic (2.99e-2)" "unprognostic (8.39e-3)" "unprognostic (5.96e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-1)" "unprognostic (4.04e-3)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.65e-3)" "unprognostic (3.62e-2)" KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 31 "Syncytiotrophoblasts: 1384.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Cell type enriched" "Detected in many" 4 "NK-cells: 1409.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 512.6;memory CD8 T-cell: 217.7;naive CD8 T-cell: 218.7;NK-cell: 737.5" "Group enriched" "Detected in many" 68 "NK-cells: 737.5;T-cells: 512.6" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 7: NK-cells - Immune response regulation" "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1931.7;Basal respiratory cells: 12085.1;Club cells: 2543.4;Ionocytes: 3922.1;Salivary duct cells: 1857.3;Suprabasal keratinocytes: 1831.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 3850.8;head and neck cancer: 2928.2" "Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 153.0;Distal enterocytes: 137.3;Ductal cells: 158.2;Proximal enterocytes: 235.7;Squamous epithelial cells: 215.3;Suprabasal keratinocytes: 358.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 251.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 146.7;granulocytes: 66.1;Hofbauer cells: 191.3;Kupffer cells: 83.7;Macrophages: 128.4;monocytes: 80.2;NK-cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 4.3;Myeloma: 2.5" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" LARGE2 "FLJ35207, GYLTL1B, PP5656" ENSG00000165905 "LARGE xylosyl- and glucuronyltransferase 2" Q8N3Y3 11 45921621-45929096 "Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 36.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 43.2;Cytotrophoblasts: 181.8;Syncytiotrophoblasts: 99.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056621 Approved "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: DU4475 - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA056621: AB_2683194" "unprognostic (9.82e-2)" "unprognostic (3.63e-2)" "unprognostic (3.65e-2)" "unprognostic (2.43e-2)" "unprognostic (6.20e-2)" "unprognostic (4.46e-3)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (2.87e-1)" "unprognostic (3.30e-2)" "unprognostic (6.94e-2)" "prognostic favorable (3.04e-12)" "unprognostic (2.31e-1)" "unprognostic (9.77e-2)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.1;granulocytes: 129.5;Hofbauer cells: 108.1;Kupffer cells: 95.4;Langerhans cells: 105.7;Macrophages: 84.5;monocytes: 53.3;NK-cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 200.2;lymphoma: 105.0" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 296.7;Hofbauer cells: 352.7;Kupffer cells: 434.2;Langerhans cells: 373.3;Late spermatids: 293.1;Macrophages: 482.1;monocytes: 755.7;NK-cells: 534.7;Schwann cells: 352.8;T-cells: 372.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 555.7;lymphoma: 804.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skin - Langerhans cells, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA019493, CAB020673" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Actin filaments, Cytosol" "CAB020673: , HPA000895: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "epididymis: 14.8;testis: 55.1" "Cell type enriched" "Detected in many" 5 "Late spermatids: 4356.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Group enriched" "Detected in many" 5 "cerebellum: 2.6;medulla oblongata: 2.4;midbrain: 1.2;pons: 2.8;thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 17.8" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 6 "cerebellum: 3.9" HPA045425 Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA045425: AB_10960538" "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (1.88e-2)" "unprognostic (4.20e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.26e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.31e-1)" "unprognostic (5.66e-6)" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-2)" LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328700-104907232 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 30.5;retina: 23.6" "Cell type enriched" "Detected in some" 19 "Oligodendrocyte precursor cells: 4587.3" "Cancer enriched" "Detected in some" 12 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.1;skin cancer: 1.2" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Vesicles "HPA069691: AB_2686171" "unprognostic (1.20e-2)" "unprognostic (6.91e-2)" "unprognostic (4.59e-3)" "unprognostic (5.03e-2)" "unprognostic (2.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-2)" "unprognostic (5.81e-2)" "unprognostic (5.99e-3)" "unprognostic (8.50e-3)" "unprognostic (3.07e-1)" "unprognostic (1.33e-1)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 8 "Hofbauer cells: 52.7;Kupffer cells: 69.8;Macrophages: 41.6;monocytes: 102.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 463.5;Kupffer cells: 217.4;Macrophages: 321.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 59: Fibroblasts - Metabolism" "Cluster 69: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.7;stomach 1: 48.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.3;Gastric mucus-secreting cells: 174.1;Intestinal goblet cells: 156.8;Ionocytes: 403.8;Proximal enterocytes: 140.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 38.6;pancreatic cancer: 33.6" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA049079 Approved "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" LMOD1 "1D, 64kD, D1" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 513.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 194.7;Leydig cells: 127.6;Peritubular cells: 278.4;Sertoli cells: 110.6;Smooth muscle cells: 324.7" "Cancer enhanced" "Detected in all" "prostate cancer: 43.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "HPA028325: AB_10600300, HPA028435: AB_10602180, HPA030097: AB_10601223" "unprognostic (3.84e-2)" "unprognostic (5.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (5.64e-1)" "unprognostic (6.35e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.73e-2)" "unprognostic (3.51e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (1.15e-2)" LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 113.3;Inhibitory neurons: 67.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 25.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 31: Non-specific - Transcription" "Cluster 38: Neurons - Neuronal signaling" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 39.5;Endometrial ciliated cells: 31.6;Glandular and luminal cells: 51.3;Prostatic glandular cells: 59.8;Sertoli cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 14.3;prostate cancer: 19.4" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA013421 Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" LRP2BP DKFZp761O0113 ENSG00000109771 "LRP2 binding protein" Q9P2M1 4 185363872-185395924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Astrocytes: 55.7;Early spermatids: 54.0;Inhibitory neurons: 33.4;Late spermatids: 51.1;Oligodendrocyte precursor cells: 38.5;Oligodendrocytes: 32.9;Rod photoreceptor cells: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036664, HPA036665" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA036664: AB_10672361, HPA036665: AB_10673660" "unprognostic (2.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-3)" "unprognostic (3.15e-5)" "unprognostic (2.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (9.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.84e-2)" "unprognostic (4.35e-4)" "unprognostic (2.17e-2)" "unprognostic (9.76e-3)" "unprognostic (2.15e-1)" "unprognostic (5.26e-3)" "unprognostic (1.29e-1)" "unprognostic (4.54e-4)" LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 604.2;Syncytiotrophoblasts: 761.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518, HPA073239" Enhanced Supported Enhanced "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 28: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292, HPA073239: " "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" LRRC36 FLJ11004 ENSG00000159708 "Leucine rich repeat containing 36" Q1X8D7 16 67326798-67385204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.3" "Group enriched" "Detected in some" 5 "Early spermatids: 173.2;Late spermatids: 140.8;Spermatocytes: 62.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 7 "dendritic cells: 9.7" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA055237, HPA058479" Enhanced Approved Vesicles,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 49: Early spermatids - Spermatogenesis" Mitochondria Vesicles "HPA055237: AB_2682751, HPA058479: AB_2683728" "unprognostic (4.59e-2)" "unprognostic (6.84e-2)" "unprognostic (2.17e-2)" "unprognostic (2.26e-5)" "unprognostic (5.27e-2)" "unprognostic (4.32e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.99e-2)" "unprognostic (1.65e-1)" "unprognostic (3.32e-3)" "unprognostic (4.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (3.70e-1)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" LRRC4 NAG14 ENSG00000128594 "Leucine rich repeat containing 4" Q9HBW1 7 128027071-128032107 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5" "Cell type enhanced" "Detected in many" "Horizontal cells: 34.0;Inhibitory neurons: 22.1;Respiratory ciliated cells: 44.8;Rod photoreceptor cells: 47.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 38.5" "Immune cell enriched" "Detected in some" 5 "neutrophil: 13.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.4" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051100 Approved "Golgi apparatus" NA NA 2100000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" "Golgi apparatus" "HPA051100: AB_2797241" "unprognostic (7.98e-2)" "unprognostic (6.15e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.34e-3)" "unprognostic (3.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (3.23e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.98e-4)" "unprognostic (4.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (5.84e-3)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 228.7;Ductal cells: 243.5;Exocrine glandular cells: 304.9;Syncytiotrophoblasts: 251.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane, Cell Junctions" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4255.5;salivary gland: 1162.5" "Group enriched" "Detected in many" 5 "Breast glandular cells: 1486.1;Club cells: 399.4;Mucus glandular cells: 1406.3;Serous glandular cells: 1394.3" "Group enriched" "Detected in all" 5 "breast cancer: 239.0;endometrial cancer: 170.3;glioma: 152.6;prostate cancer: 195.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Cancer enriched" "Detected in single" 5 "Myeloma: 2.9" "Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" NA NA 350000000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 30: Breast - Lactation" "CAB008646: AB_1618695, CAB016201: AB_629860, HPA057177: AB_2683361, HPA059976: AB_2684185" "unprognostic (7.24e-3)" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.14e-3)" "unprognostic (3.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.04e-1)" "prognostic favorable (6.30e-5)" "unprognostic (1.66e-2)" "unprognostic (3.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-3)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 10 "B-cells: 154.3;Hofbauer cells: 258.4;Kupffer cells: 157.5;Langerhans cells: 123.9;Macrophages: 146.7;Microglial cells: 103.1;monocytes: 146.5;Schwann cells: 66.4" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Group enriched" "Detected in some" 176 "Leukemia: 38.8;lymphoma: 38.4;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 211.1;dendritic cells: 162.4;Hofbauer cells: 164.2;Macrophages: 197.4;monocytes: 535.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 404.8;Kupffer cells: 407.4;Macrophages: 500.9;monocytes: 673.1;Squamous epithelial cells: 374.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cancer enhanced" "Detected in many" "Bone cancer: 31.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 26.6;dendritic cells: 39.8;Langerhans cells: 29.3;Macrophages: 25.5;Plasma cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 34: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 10.8;choroid plexus: 13.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Granulosa cells: 7.5;Theca cells: 19.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.7" "Kidney - Ascending Loop of Henle cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;retina: 9.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 48.9;Inhibitory neurons: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 354.6;Early spermatids: 343.2;Oligodendrocytes: 1417.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol Microtubules "HPA029712: AB_10600303, HPA029713: AB_10601339" "unprognostic (8.68e-3)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.33e-3)" "unprognostic (4.35e-3)" "unprognostic (6.95e-2)" "unprognostic (3.35e-1)" "prognostic favorable (9.22e-4)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (4.61e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.07e-7)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "unprognostic (3.62e-1)" "unprognostic (6.51e-2)" MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 79.0;neutrophil: 24.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 79.0" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 970000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: Non-specific - Protein binding" "Cluster 33: Macrophages - Degranulation" "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in many" "Astrocytes: 196.4;Excitatory neurons: 103.9;Inhibitory neurons: 56.8;Late spermatids: 56.8;Muller glia cells: 56.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4;skin cancer: 5.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Alveolar cells type 1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Enzymes" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" MBIP ENSG00000151332 "MAP3K12 binding inhibitory protein 1" Q9NS73 14 36298564-36320637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 236.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 30.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003388 Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 1: Thyroid gland - Transcription" "Cluster 46: Non-specific - Unknown function" "Cluster 41: Alveolar cells - Lung function" Cytosol "Nucleoplasm, Nucleoli" "HPA003388: AB_1079322" "unprognostic (8.79e-2)" "unprognostic (9.92e-2)" "unprognostic (5.07e-2)" "unprognostic (8.66e-2)" "unprognostic (9.85e-2)" "unprognostic (4.71e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.52e-4)" "unprognostic (5.24e-2)" "prognostic favorable (1.14e-4)" "unprognostic (4.65e-1)" "unprognostic (9.27e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-1)" "unprognostic (1.74e-3)" "unprognostic (1.09e-1)" MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 8 "Adipocytes: 63.0;Endothelial cells: 36.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cancer enhanced" "Detected in some" "ovarian cancer: 16.2;Rhabdoid: 19.3;Uterine cancer: 11.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 91.1;Cytotrophoblasts: 76.5;Glandular and luminal cells: 140.3;Salivary duct cells: 115.3;Thymic epithelial cells: 73.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 46: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.9;Extravillous trophoblasts: 1260.6;Fibroblasts: 678.9;Syncytiotrophoblasts: 285.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "ovarian cancer: 94.1;testis cancer: 137.1" "Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.2;Kupffer cells: 211.1;Macrophages: 207.6;monocytes: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 289.6;Basal prostatic cells: 215.8;Hepatocytes: 294.2;Proximal enterocytes: 204.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 70: Basal prostatic cells - Lipid metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" MIPOL1 CCDC193 ENSG00000151338 "Mirror-image polydactyly 1" Q8TD10 14 37197913-37552361 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 120.4;Excitatory neurons: 157.1;Inhibitory neurons: 137.9;Late spermatids: 147.3;Oligodendrocyte precursor cells: 87.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002893, HPA050179" Enhanced Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 46: Non-specific - Unknown function" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA002893: AB_1079386, HPA050179: AB_2681043" "unprognostic (3.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-1)" "unprognostic (4.30e-2)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "unprognostic (4.61e-4)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (2.39e-2)" "unprognostic (3.54e-2)" "unprognostic (8.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.17e-1)" "unprognostic (9.78e-3)" "unprognostic (3.41e-3)" "unprognostic (1.85e-2)" MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 12 "Plasma cells: 22.7" "Cancer enriched" "Detected in some" 9 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 35: Liver cancer - Metabolism" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "HPA005662: AB_2667382" "unprognostic (4.09e-2)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (7.40e-3)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.71e-13)" "unprognostic (1.54e-1)" "unprognostic (1.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.47e-2)" MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 90.5;Enteroendocrine cells: 83.8;Hepatocytes: 201.1;Kupffer cells: 87.5;Proximal enterocytes: 93.9;Skeletal myocytes: 49.5" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 21.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 29: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 2300.4" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.5" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 38: Neurons - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 26.7;testis: 15.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.5;Oligodendrocytes: 22.0;Plasma cells: 5.7;Spermatogonia: 4.8;Squamous epithelial cells: 8.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043499 Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 17: RS4;11 - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "HPA043499: AB_2732506" "unprognostic (2.21e-2)" "unprognostic (6.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (6.21e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.28e-2)" "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (2.71e-8)" "unprognostic (7.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.84e-2)" "unprognostic (7.64e-2)" MOBP ENSG00000168314 "Myelin associated oligodendrocyte basic protein" Q13875 3 39467198-39529479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 918.8" "Cell type enriched" "Detected in some" 13 "Oligodendrocytes: 1517.1" "Cancer enriched" "Detected in single" 63 "glioma: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA035152 Enhanced Supported "Cytoplasmic bodies" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 2: DU4475 - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Cytoplasmic bodies" "HPA035152: AB_10603020" "unprognostic (1.76e-2)" "unprognostic (2.34e-1)" "unprognostic (3.53e-2)" "unprognostic (7.35e-2)" "unprognostic (5.67e-2)" "unprognostic (3.60e-2)" "unprognostic (7.47e-2)" "unprognostic (2.82e-1)" "unprognostic (7.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (2.04e-5)" "unprognostic (2.28e-1)" "unprognostic (8.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" MPP5 "FLJ12615, PALS1" ENSG00000072415 "Membrane palmitoylated protein 5" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "Plasma membrane, Cytosol" "HPA000993: AB_1079407, HPA063890: AB_2732707" "unprognostic (3.65e-1)" "unprognostic (3.82e-3)" "unprognostic (4.56e-2)" "unprognostic (9.20e-2)" "unprognostic (9.86e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-3)" "unprognostic (9.89e-3)" "prognostic favorable (1.71e-12)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (6.90e-2)" "unprognostic (6.87e-2)" MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 91.1;Excitatory neurons: 75.5;Suprabasal keratinocytes: 83.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 294.4;Basal respiratory cells: 269.4;Glandular and luminal cells: 182.6;Squamous epithelial cells: 371.0;Suprabasal keratinocytes: 444.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.7;Kupffer cells: 305.4;Macrophages: 613.9;monocytes: 1048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cancer enhanced" "Detected in some" "Leukemia: 7.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 418.6;Hepatocytes: 471.9;Kupffer cells: 264.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25147.7;heart muscle: 26116.9;skeletal muscle: 25697.4" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 32207.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (2.87e-1)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-3)" "unprognostic (1.06e-2)" "unprognostic (3.01e-1)" "unprognostic (3.29e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.31e-5)" "unprognostic (9.93e-3)" "unprognostic (8.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.68e-2)" MT-ND6 "MTND6, NAD6, ND6" ENSG00000198695 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6" P03923 MT 14149-14673 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 35802.7;skeletal muscle: 57879.2" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 12019.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (1.96e-1)" "unprognostic (3.27e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (1.03e-3)" "unprognostic (6.02e-3)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (6.06e-3)" "unprognostic (2.91e-1)" "prognostic favorable (8.91e-6)" "unprognostic (3.64e-2)" "unprognostic (1.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.92e-2)" MTHFD2L MGC72244 ENSG00000163738 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" Q9H903 4 74114174-74303099 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035434 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 30: Breast - Lactation" "HPA035434: AB_10601038" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (2.03e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-2)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (7.73e-3)" "unprognostic (1.42e-4)" "unprognostic (3.45e-3)" "unprognostic (4.23e-2)" "unprognostic (5.07e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (1.19e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-3)" MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Enzymes" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17800917 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 403.7;Oligodendrocytes: 442.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoli, Microtubules" "HPA067903: AB_2685921, HPA069795: AB_2686198" "unprognostic (3.20e-1)" "unprognostic (3.29e-1)" "prognostic favorable (1.05e-4)" "unprognostic (2.50e-2)" "unprognostic (2.27e-1)" "unprognostic (7.72e-3)" "unprognostic (1.36e-1)" "unprognostic (1.86e-3)" "unprognostic (2.44e-1)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (3.33e-1)" "prognostic favorable (2.76e-4)" "unprognostic (2.04e-1)" "unprognostic (2.38e-2)" "unprognostic (2.53e-3)" "unprognostic (2.43e-1)" MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 135.8;esophagus: 696.3;vagina: 244.5" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 524.9" "Group enriched" "Detected in many" 9 "cervical cancer: 6.8;head and neck cancer: 6.6;lung cancer: 13.9;stomach cancer: 7.0;thyroid cancer: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "lung cancer: 2.2" "Lung - Alveolar cells type 2" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA052028: AB_2681700" "unprognostic (2.27e-2)" "unprognostic (4.85e-3)" "unprognostic (5.24e-3)" "unprognostic (1.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.98e-3)" "unprognostic (1.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" MYO5C MGC74969 ENSG00000128833 "Myosin VC" Q9NQX4 15 52192322-52295804 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Alveolar cells type 1: 107.7;Alveolar cells type 2: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020790, HPA032115, HPA032116" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 41: Alveolar cells - Lung function" Cytosol Nucleoplasm "CAB020790: , HPA032115: AB_2674158, HPA032116: AB_2674159" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "prognostic favorable (5.18e-5)" "unprognostic (2.94e-1)" "unprognostic (4.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.53e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-3)" "unprognostic (4.82e-2)" "prognostic favorable (2.47e-5)" "prognostic favorable (5.82e-4)" "unprognostic (9.15e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" MYOZ2 "C4orf5, CS-1, FATZ-2" ENSG00000172399 "Myozenin 2" Q9NPC6 4 119135832-119187789 "Disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 771.4;skeletal muscle: 225.5;tongue: 173.4" "Cell type enriched" "Detected in some" 39 "Cardiomyocytes: 3128.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Rhabdoid: 1.2;Sarcoma: 3.4;skin cancer: 3.6;testis cancer: 1.0" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035763, HPA035764" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: Skin cancer - Membrane components" "Cluster 77: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA035763: AB_2674770, HPA035764: AB_10696509" "unprognostic (2.53e-1)" "unprognostic (9.20e-2)" "unprognostic (6.94e-2)" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.34e-2)" "unprognostic (5.71e-1)" "unprognostic (2.18e-1)" "unprognostic (4.77e-2)" "unprognostic (4.04e-1)" "unprognostic (8.25e-2)" "unprognostic (5.07e-2)" "unprognostic (6.19e-7)" "unprognostic (6.66e-4)" "unprognostic (2.43e-1)" "unprognostic (3.06e-1)" "unprognostic (2.83e-2)" MYRF "C11orf9, MRF, Ndt80, pqn-47" ENSG00000124920 "Myelin regulatory factor" Q9Y2G1 11 61752636-61788518 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 168.0;stomach 1: 88.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 79.6;Cholangiocytes: 52.0;Gastric mucus-secreting cells: 119.8;Oligodendrocytes: 241.5;Thymic epithelial cells: 69.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 47.4" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018310 Approved Nucleoplasm,Cytosol NA NA 1400000 "Cluster 70: Brain - Nervous system development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA018310: AB_1845534" "unprognostic (3.51e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (5.39e-2)" "unprognostic (1.54e-1)" "unprognostic (3.65e-2)" "unprognostic (1.34e-1)" "unprognostic (9.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.91e-3)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.1;Paneth cells: 34.1;Respiratory ciliated cells: 24.8" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "CAB017782, HPA043704" Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 50: Enterocytes - Absorption" "CAB017782: , HPA043704: AB_2678625" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 45.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 263.7;Kupffer cells: 154.3;Langerhans cells: 170.6;Macrophages: 199.3;monocytes: 262.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 63.9;lymphoma: 45.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 72.8;granulocytes: 74.1;Hofbauer cells: 204.4;Kupffer cells: 58.9;Langerhans cells: 56.1;Macrophages: 98.8;Plasma cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Group enriched" "Detected in some" 7 "Leukemia: 116.3;lymphoma: 49.4" "Breast - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Astrocytes: 463.7;Oligodendrocyte precursor cells: 741.8;Oligodendrocytes: 2036.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.3" "Adipose subcutaneous - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 47: Retina - Visual perception" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 67.3;Inhibitory neurons: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 55: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.0;Alveolar cells type 2: 42.5;Bipolar cells: 64.3;Early spermatids: 157.2;Late spermatids: 266.5" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" NEBL "bA165O3.1, C10orf113, LASP2, LNEBL" ENSG00000078114 Nebulette O76041 10 20779973-21293011 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "heart muscle: 312.0" "Group enriched" "Detected in many" 4 "Astrocytes: 921.4;Cardiomyocytes: 3250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 9.8" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013994, HPA013995" Approved NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA013994: AB_1854359, HPA013995: AB_1854360" "unprognostic (3.79e-2)" "unprognostic (1.92e-3)" "unprognostic (3.44e-2)" "unprognostic (3.57e-3)" "unprognostic (1.50e-1)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.25e-2)" "unprognostic (1.05e-1)" "unprognostic (6.20e-3)" "unprognostic (2.36e-2)" "unprognostic (8.42e-2)" "prognostic favorable (2.77e-8)" "unprognostic (3.51e-1)" "unprognostic (8.11e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (5.56e-4)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enhanced" "Detected in many" "Ionocytes: 90.9;Squamous epithelial cells: 111.1;Suprabasal keratinocytes: 185.4;Syncytiotrophoblasts: 467.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 29.0" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 642.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Group enriched" "Detected in many" 6 "Bone cancer: 139.8;Neuroblastoma: 54.7" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 14: Bone cancer - Transcription" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 157.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Cancer enriched" "Detected in many" 7 "Leukemia: 90.2" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skin - Keratinocyte (granular), Stomach - Neutrophils, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Cell type enriched" "Detected in many" 5 "NK-cells: 6101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 26 "Leukemia: 62.9;lymphoma: 64.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" NLRP12 "CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2" ENSG00000142405 "NLR family pyrin domain containing 12" P59046 19 53793741-53824394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.3" "Group enriched" "Detected in some" 5 "Hofbauer cells: 6.7;Kupffer cells: 14.4;Macrophages: 7.8;monocytes: 9.9" "Cancer enriched" "Detected in single" 5 "testis cancer: 2.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;classical monocyte: 18.1;eosinophil: 23.2;neutrophil: 29.8" "Group enriched" "Detected in many" 5 "granulocytes: 56.9;monocytes: 18.1" "Cancer enhanced" "Detected in single" "Leukemia: 1.8" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042981 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA042981: AB_10795712" "unprognostic (6.92e-2)" "unprognostic (3.11e-1)" "unprognostic (6.66e-3)" "unprognostic (9.82e-2)" "unprognostic (1.81e-4)" "unprognostic (3.90e-2)" "unprognostic (5.79e-2)" "unprognostic (6.26e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-5)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-2)" "unprognostic (4.48e-1)" NLRP6 "CLR11.4, NALP6, PAN3, PYPAF5" ENSG00000174885 "NLR family pyrin domain containing 6" P59044 11 278407-285388 "Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 39.9" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 9.8;T-cells: 3.7" "Group enriched" "Detected in some" 4 "colorectal cancer: 0.9;liver cancer: 1.2;renal cancer: 1.5;stomach cancer: 1.8" "Region enhanced" "Detected in single" "cerebral cortex: 3.6" "Group enriched" "Detected in many" 4 "neutrophil: 15.4;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.4;monocytes: 4.6" "Cancer enhanced" "Detected in some" "Leukemia: 1.1;lymphoma: 1.3;Myeloma: 2.0" "Adipose visceral - Neutrophils, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043681, HPA048500" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA043681: AB_2678614, HPA048500: AB_2680422" "unprognostic (6.37e-3)" "unprognostic (4.69e-2)" "unprognostic (4.26e-2)" "unprognostic (3.42e-2)" "unprognostic (6.40e-2)" "unprognostic (1.18e-2)" "prognostic favorable (4.23e-5)" "unprognostic (8.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (2.19e-1)" "unprognostic (3.11e-3)" "unprognostic (4.96e-2)" "unprognostic (2.14e-2)" "unprognostic (6.90e-3)" "unprognostic (3.69e-2)" NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 63.2;Oligodendrocyte precursor cells: 58.7;Paneth cells: 57.7;Rod photoreceptor cells: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.7;Basal squamous epithelial cells: 48.6;Breast myoepithelial cells: 11.7;Peritubular cells: 11.0;Sertoli cells: 13.8;Smooth muscle cells: 18.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.3" "Cell type enhanced" "Detected in some" "Peritubular cells: 28.4;Sertoli cells: 33.2;Spermatogonia: 8.2" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 6.7;Neuroblastoma: 7.3;testis cancer: 5.1" "Lung - Fibroblast_2, Testis - Sertoli cells" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Club cells: 912.1;Ductal cells: 550.8;Enteroendocrine cells: 425.1;Exocrine glandular cells: 1845.5;Undifferentiated cells: 2310.8" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "colorectal cancer: 127.6;Gastric cancer: 51.3" "Colon - Colon enterocytes, Lung - Neutrophil_1, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706421 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 189.0;retina: 92.2" "Group enriched" "Detected in some" 7 "Collecting duct cells: 7.9;Rod photoreceptor cells: 19.1" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 44: Photoreceptor cells - Visual perception" "unprognostic (1.59e-2)" "unprognostic (3.74e-1)" "unprognostic (8.03e-2)" "unprognostic (9.77e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.84e-2)" "unprognostic (3.06e-1)" "unprognostic (9.27e-2)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" OVOL1 HOVO1 ENSG00000172818 "Ovo like transcriptional repressor 1" O14753 11 65787063-65797214 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 57.2;skin 1: 51.0;testis: 35.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 110.5;Late spermatids: 92.3;Squamous epithelial cells: 134.2;Suprabasal keratinocytes: 95.5;Syncytiotrophoblasts: 306.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003984 Uncertain Approved Nucleoplasm Yes NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA003984: AB_1854854" "unprognostic (4.26e-3)" "unprognostic (3.39e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (3.37e-1)" "unprognostic (1.26e-2)" "unprognostic (1.95e-1)" "unprognostic (2.31e-2)" "unprognostic (2.01e-3)" "unprognostic (1.91e-1)" "prognostic favorable (1.00e-13)" "unprognostic (4.26e-2)" "unprognostic (3.51e-2)" "unprognostic (2.42e-1)" "unprognostic (9.04e-3)" P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 68.5;Granulosa cells: 118.5;Microglial cells: 89.4;Prostatic glandular cells: 65.1;Theca cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cancer enhanced" "Detected in all" "Kidney cancer: 118.0" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 68: Kidney - Mixed function" "Cluster 17: Granulosa cells - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" P4HTM "EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4" ENSG00000178467 "Prolyl 4-hydroxylase, transmembrane" Q9NXG6 3 48989889-49007153 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 161.3;Respiratory ciliated cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007199 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 63: Non-specific - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "Vesicles, Cytosol" "HPA007199: AB_1855272" "unprognostic (1.95e-2)" "unprognostic (3.12e-2)" "unprognostic (9.47e-2)" "prognostic favorable (8.18e-4)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-2)" "prognostic favorable (3.28e-5)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (2.60e-2)" "unprognostic (9.65e-3)" PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 9 "B-cells: 112.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 11 "Leukemia: 32.8;lymphoma: 76.6" "Lung - B-cells, Skin - Outer root sheath cells" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm "CAB026269: , CAB026869: , HPA056394: AB_2683116" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 159.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4204.4;Excitatory neurons: 5180.8;Inhibitory neurons: 2437.4;Oligodendrocyte precursor cells: 6046.3;Oligodendrocytes: 13327.1" "Cancer enriched" "Detected in single" 8 "glioma: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cancer enhanced" "Detected in many" "liver cancer: 16.6;Rhabdoid: 31.4" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Centrosome" "HPA015581: AB_1855048" "unprognostic (1.77e-1)" "unprognostic (8.36e-2)" "unprognostic (9.12e-3)" "unprognostic (4.42e-5)" "unprognostic (7.54e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (8.47e-4)" "unprognostic (6.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.35e-4)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 508.7;Fibroblasts: 353.8;Leydig cells: 145.9;Smooth muscle cells: 366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 216.0;Neuroblastoma: 221.5;Sarcoma: 153.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 239.9;Excitatory neurons: 309.6;Oligodendrocyte precursor cells: 713.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 6.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.9;Ionocytes: 13.5;Suprabasal keratinocytes: 21.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "head and neck cancer: 10.6" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.0;Excitatory neurons: 47.8;Inhibitory neurons: 15.0;Thymic epithelial cells: 34.2" "Cancer enhanced" "Detected in many" "glioma: 6.3;thyroid cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Lung - Fibroblast_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 101.1;basal ganglia: 300.5;cerebellum: 251.7;cerebral cortex: 256.5;hippocampal formation: 296.8" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Mitochondria Nucleoplasm "HPA068030: AB_2685944, HPA069318: AB_2686117" "unprognostic (1.19e-2)" "unprognostic (2.33e-2)" "unprognostic (3.06e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.80e-1)" "unprognostic (3.01e-2)" "unprognostic (7.44e-3)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (4.44e-5)" "unprognostic (8.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (4.09e-3)" PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 405.4;Basal squamous epithelial cells: 515.4;Serous glandular cells: 276.8;Squamous epithelial cells: 1186.7;Suprabasal keratinocytes: 1131.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 152.7" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.3;Distal enterocytes: 250.2;Extravillous trophoblasts: 189.3;Proximal enterocytes: 184.4;Suprabasal keratinocytes: 357.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 16.8;Basal keratinocytes: 4.1;Breast glandular cells: 7.6;Suprabasal keratinocytes: 20.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.8" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 30: Breast - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" PLAGL2 ZNF900 ENSG00000126003 "PLAG1 like zinc finger 2" Q9UPG8 20 32192504-32207743 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.2" "Cell type enhanced" "Detected in all" "Late spermatids: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "intermediate monocyte: 18.3;non-classical monocyte: 34.8" "Lineage enriched" "Detected in many" 15 "monocytes: 34.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005900 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA005900: AB_1079629" "unprognostic (9.40e-2)" "unprognostic (1.67e-1)" "unprognostic (6.95e-3)" "unprognostic (1.09e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-3)" "unprognostic (8.63e-2)" "unprognostic (8.97e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-2)" "unprognostic (2.26e-1)" "unprognostic (3.08e-1)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (7.90e-2)" "unprognostic (1.09e-1)" PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6;retina: 12.4" "Group enriched" "Detected in many" 4 "Astrocytes: 90.8;Early spermatids: 237.2;Excitatory neurons: 124.0;Inhibitory neurons: 128.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.4" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Astrocytes: 52.2;Hepatocytes: 104.9;Serous glandular cells: 85.8;Skeletal myocytes: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 21: Serous glandular cells - Salivary secretion" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1473.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 181.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;Granulosa cells: 1.5;Late spermatids: 1.7;Oligodendrocyte precursor cells: 1.4;Proximal enterocytes: 1.7;Proximal tubular cells: 5.7;Suprabasal keratinocytes: 2.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Kidney - Proximal tubular cells, Lung - Neutrophil_2, Skin - Keratinocyte (other), Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.1;Early spermatids: 41.2;Extravillous trophoblasts: 35.6;Late spermatids: 76.9;Spermatocytes: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 521.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in all" 8 "lymphoma: 193.4;Myeloma: 230.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 12.4;Basal prostatic cells: 14.3;Collecting duct cells: 9.8;Gastric mucus-secreting cells: 9.5;Ionocytes: 10.8;Suprabasal keratinocytes: 23.7;Syncytiotrophoblasts: 11.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.0" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 56: Neurons - Neuronal signaling" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" PPP2R5A "B56A, B56alpha, PR61A" ENSG00000066027 "Protein phosphatase 2 regulatory subunit B'alpha" Q15172 1 212285410-212361853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 246.3;Late spermatids: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059288, HPA078841" Approved Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: Non-specific - RNA binding" "Cluster 6: Late spermatids - Spermatogenesis" Cytosol "HPA059288: AB_2683966, HPA078841: " "unprognostic (3.56e-1)" "unprognostic (2.71e-1)" "unprognostic (8.48e-2)" "unprognostic (2.54e-1)" "unprognostic (9.21e-2)" "unprognostic (1.01e-1)" "unprognostic (5.01e-2)" "unprognostic (1.12e-2)" "unprognostic (8.07e-2)" "unprognostic (1.84e-2)" "unprognostic (3.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.40e-3)" "unprognostic (8.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" PPP4R4 "CFAP14, KIAA1622, PP4R4" ENSG00000119698 "Protein phosphatase 4 regulatory subunit 4" Q6NUP7 14 94146128-94279734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Group enriched" "Detected in many" 5 "Astrocytes: 43.0;Cone photoreceptor cells: 27.6;Early spermatids: 18.5;Excitatory neurons: 62.3;Granulosa cells: 18.3;Inhibitory neurons: 61.6;Late spermatids: 15.8;Oligodendrocyte precursor cells: 16.8;Spermatocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.0" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041866, HPA050321" Approved Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA041866: AB_10804120, HPA050321: AB_2681086" "unprognostic (2.65e-3)" "unprognostic (3.06e-1)" "unprognostic (9.07e-2)" "unprognostic (9.49e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (2.45e-1)" "unprognostic (1.25e-1)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (1.72e-2)" "unprognostic (8.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (6.24e-2)" PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: Non-specific - RNA binding" "Cluster 40: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2616.3" "Group enriched" "Detected in some" 7 "Erythroid cells: 35.4;Extravillous trophoblasts: 107.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.2" "Lineage enriched" "Detected in single" 73 "granulocytes: 7.2" "Cancer enriched" "Detected in some" 47 "Leukemia: 365.0" "Lung - Neutrophil_1" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" NA NA 100000000 "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 62: Granulocytes - Innate immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA038515: AB_10675800" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (3.49e-1)" "unprognostic (8.62e-4)" "unprognostic (4.77e-3)" "unprognostic (3.20e-2)" "unprognostic (4.17e-2)" "unprognostic (2.26e-2)" "unprognostic (5.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.40e-11)" "unprognostic (4.26e-2)" "unprognostic (4.52e-3)" "unprognostic (6.47e-2)" "unprognostic (2.32e-1)" PRG3 "MBP2, MBPH" ENSG00000156575 "Proteoglycan 3, pro eosinophil major basic protein 2" Q9Y2Y8 11 57376769-57381150 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "bone marrow: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "Leukemia: 2.9" "Lung - Neutrophil_1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 3.5" HPA064183 Enhanced "Secreted in other tissues" NA NA 680000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 62: Granulocytes - Innate immune response" "HPA064183: AB_2685205" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 260.9;NK-cells: 221.1;T-cells: 121.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" PRKG2 "cGKII, PKG2, PRKGR2" ENSG00000138669 "Protein kinase cGMP-dependent 2" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.1;prostate: 9.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 32.2;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 102.0;Prostatic glandular cells: 26.1;Proximal enterocytes: 18.7" "Group enriched" "Detected in some" 4 "melanoma: 4.1;prostate cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 18: Non-specific - Mixed function" "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 54.6;Extravillous trophoblasts: 39.0;Granulosa cells: 26.7;Undifferentiated cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 122.4;Basal squamous epithelial cells: 127.9;Squamous epithelial cells: 148.1;Suprabasal keratinocytes: 189.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 10 "Horizontal cells: 19.9;Inhibitory neurons: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 29.4;Neuroblastoma: 62.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Neutrophil_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 151.2;Club cells: 243.7;Ductal cells: 107.1;Ionocytes: 452.1;Respiratory ciliated cells: 117.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 23.8" "Colon - Colon enterocytes, Kidney - Endothelial cells, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "bone marrow: 165.3" "Cell type enriched" "Detected in some" 6 "Erythroid cells: 70.2" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 177 "Leukemia: 199.8" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 71: Erythroid cells - Oxygen transport" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 268.2;Extravillous trophoblasts: 775.7;Proximal enterocytes: 336.5;Syncytiotrophoblasts: 640.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.4;Cone photoreceptor cells: 93.1;Oligodendrocyte precursor cells: 49.6;Rod photoreceptor cells: 77.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "testis cancer: 172.9" "Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: BEWO - Unknown function" "Cluster 44: Photoreceptor cells - Visual perception" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 3013.6;Kupffer cells: 1947.7;Macrophages: 1803.4;monocytes: 2022.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 69: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.9;lymphoid tissue: 6.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 16.4;NK-cells: 118.8;T-cells: 29.8;Undifferentiated cells: 27.6" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 68.0;NK-cell: 90.3" "Group enriched" "Detected in many" 33 "NK-cells: 90.3;T-cells: 68.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.8" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Stomach - Fibroblasts, Thyroid - T-cells" "Low region specificity" "Detected in some" HPA049668 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 80.7;urinary bladder: 81.7" "Cell type enriched" "Detected in many" 4 "Thymic epithelial cells: 448.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.4" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.3;Erythroid cells: 44.1;Extravillous trophoblasts: 51.2;Spermatocytes: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 53.3;Excitatory neurons: 80.7;Horizontal cells: 96.1;Intestinal goblet cells: 122.3;Oligodendrocyte precursor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" RARB "HAP, NR1B2, RRB2" ENSG00000077092 "Retinoic acid receptor beta" P10826 3 25174332-25597932 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Microphthalmia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.2;Excitatory neurons: 65.8;Inhibitory neurons: 90.6;Microglial cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Region enriched" "Detected in all" 9 "basal ganglia: 109.2" "CAB002617, HPA004174" Enhanced Enhanced Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "CAB002617: , HPA004174: AB_1079744" "unprognostic (2.04e-2)" "unprognostic (3.53e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.43e-1)" "unprognostic (4.71e-2)" "unprognostic (1.62e-1)" "unprognostic (2.86e-1)" "prognostic favorable (3.43e-5)" "unprognostic (9.24e-3)" "unprognostic (2.28e-1)" "unprognostic (9.99e-2)" "unprognostic (6.56e-3)" RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 221.9;fallopian tube: 206.4" "Cell type enhanced" "Detected in many" "Club cells: 987.3;Ionocytes: 380.3;Mucus glandular cells: 970.9;Salivary duct cells: 800.8;Thymic epithelial cells: 1760.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bile duct cancer: 60.1;breast cancer: 239.9;pancreatic cancer: 81.4" "Lung - Fibroblast_2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 314.2;Glandular and luminal cells: 83.5;Intestinal goblet cells: 90.2;Mucus glandular cells: 84.7;Prostatic glandular cells: 135.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 52: Spermatids - Smell perception" "Cluster 58: Gastric mucus-secreting cells - Digestion" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" RBP2 "CRABP-II, CRBP2, CRBPII, RBPC2" ENSG00000114113 "Retinol binding protein 2" P50120 3 139452884-139480747 "Metabolic proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 294 "intestine: 2713.5" "Cell type enriched" "Detected in some" 41 "Proximal enterocytes: 7177.3" "Group enriched" "Detected in many" 4 "colorectal cancer: 7.1;pancreatic cancer: 4.5;stomach cancer: 8.4;testis cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 13.1;ovarian cancer: 25.7" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA035866 Enhanced Approved "Golgi apparatus" NA NA 140000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 61: Liver - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Golgi apparatus" "HPA035866: AB_10672232" "unprognostic (1.74e-1)" "unprognostic (2.66e-2)" "unprognostic (3.34e-2)" "unprognostic (6.72e-6)" "unprognostic (2.33e-1)" "unprognostic (4.10e-2)" "unprognostic (1.56e-2)" "unprognostic (2.24e-1)" "unprognostic (8.51e-3)" "unprognostic (3.92e-2)" "unprognostic (7.35e-2)" "unprognostic (1.24e-3)" "unprognostic (5.57e-3)" "unprognostic (1.10e-1)" "unprognostic (9.23e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Plasma cells: 11.3;Spermatocytes: 23.9;Spermatogonia: 16.8;Undifferentiated cells: 15.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 79.2;Hofbauer cells: 173.9;Macrophages: 44.2;Melanocytes: 50.5;Proximal tubular cells: 167.8" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Group enriched" "Detected in many" 6 "Leukemia: 20.6;Myeloma: 22.9;skin cancer: 50.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 60: Proximal tubular cells - Absorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "dendritic cells: 36.1;Kupffer cells: 95.2;Langerhans cells: 37.1;Macrophages: 65.8;monocytes: 148.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.1" "Cancer enriched" "Detected in some" 4 "Leukemia: 18.1" "Lung - Neutrophil_2, Prostate - Macrophages, Testis - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 340000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 4: Platelets - Platelet activation" "Golgi apparatus" "HPA028727: AB_2797219, HPA045780: AB_10962728" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (8.66e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-2)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.30e-3)" "unprognostic (8.21e-3)" "unprognostic (2.81e-4)" "unprognostic (1.73e-2)" "unprognostic (9.91e-2)" RHAG "CD241, RH50A, SLC42A1" ENSG00000112077 "Rh associated glycoprotein" Q02094 6 49605175-49636839 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "bone marrow: 119.6" "Cell type enriched" "Detected in some" 16 "Erythroid cells: 370.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 103.0" "Liver - Erythroid cells, Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA046051, HPA055331" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "HPA046051: , HPA055331: AB_2682785" "unprognostic (8.16e-2)" "unprognostic (6.86e-2)" "unprognostic (1.25e-3)" "unprognostic (1.65e-1)" RHEBL1 "FLJ25797, MGC34869, RHEB2" ENSG00000167550 "RHEB like 1" Q8TAI7 12 49064676-49070025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.0;Excitatory neurons: 6.8;Granulosa cells: 12.8;NK-cells: 15.0;Plasma cells: 7.5;Respiratory ciliated cells: 10.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.1" "Group enriched" "Detected in all" 5 "granulocytes: 16.1;T-cells: 10.4" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA053111, HPA061001" Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Centrosome" "HPA053111: AB_2682047, HPA061001: AB_2684409" "unprognostic (2.94e-1)" "unprognostic (1.11e-3)" "unprognostic (2.36e-2)" "unprognostic (9.81e-3)" "unprognostic (8.76e-2)" "unprognostic (2.03e-2)" "unprognostic (3.03e-5)" "unprognostic (9.13e-2)" "unprognostic (9.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.98e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-10)" "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (7.66e-2)" "unprognostic (2.07e-1)" RIPOR2 "C6orf32, DIFF48, FAM65B, KIAA0386, MYONAP" ENSG00000111913 "RHO family interacting cell polarization regulator 2" Q9Y4F9 6 24804282-25042170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Differentiation, Hearing, Myogenesis" "Developmental protein, Signal transduction inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.6" "Cell type enhanced" "Detected in many" "B-cells: 259.2;dendritic cells: 148.2;Kupffer cells: 249.2;monocytes: 273.0;NK-cells: 202.2;Syncytiotrophoblasts: 141.6;T-cells: 143.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 951.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 951.9" "Cancer enhanced" "Detected in many" "lymphoma: 46.0" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (4.05e-3)" "unprognostic (1.34e-3)" "unprognostic (3.55e-2)" "unprognostic (1.91e-2)" "unprognostic (1.47e-2)" "unprognostic (1.75e-2)" "unprognostic (5.89e-4)" "unprognostic (2.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.40e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-2)" "unprognostic (8.55e-2)" "unprognostic (3.33e-2)" "unprognostic (2.30e-2)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.3;Erythroid cells: 41.7;Peritubular cells: 44.6;Spermatocytes: 44.4;Spermatogonia: 53.5;Syncytiotrophoblasts: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 124.1" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 28: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 133.7;dendritic cells: 427.9;Hofbauer cells: 263.8;Kupffer cells: 391.5;Langerhans cells: 225.3;Macrophages: 270.2;Schwann cells: 226.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 22.4;lymphoma: 7.3;Myeloma: 9.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Astrocytes: 28.2;Intestinal goblet cells: 23.4;Undifferentiated cells: 33.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 44.6;colorectal cancer: 72.4;Gastric cancer: 38.7" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 17 "Excitatory neurons: 74.3;Inhibitory neurons: 84.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.9;Rhabdoid: 6.2" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Testis - Spermatogonia" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 20.2;Endothelial cells: 18.7;Fibroblasts: 49.6;Inhibitory neurons: 17.3;Leydig cells: 27.9;Smooth muscle cells: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.2;Rhabdoid: 19.5" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 61: Liver - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" RTKN2 "bA531F24.1, Em:AC024597.2, FLJ39352, PLEKHK1" ENSG00000182010 "Rhotekin 2" Q8IZC4 10 62183035-62268844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 77.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 107.1;Early spermatids: 456.7;Late spermatids: 168.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Immune cell enriched" "Detected in some" 8 "T-reg: 16.7" "Lineage enriched" "Detected in single" 72 "T-cells: 16.7" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037946, HPA038446" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 19: Lung - Lung function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Nucleoplasm Mitochondria "HPA037946: AB_10795398, HPA038446: AB_10796218" "unprognostic (2.33e-1)" "unprognostic (2.59e-1)" "unprognostic (2.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.26e-1)" "unprognostic (8.92e-3)" "unprognostic (6.66e-5)" "unprognostic (7.81e-3)" "unprognostic (2.33e-2)" "unprognostic (3.24e-1)" "unprognostic (3.72e-2)" "unprognostic (9.48e-4)" "unprognostic (3.70e-11)" "unprognostic (3.95e-2)" "unprognostic (9.34e-3)" "unprognostic (4.68e-3)" "unprognostic (1.55e-1)" S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;brain: 60.2" "Cell type enriched" "Detected in some" 6 "NK-cells: 173.2" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 299.4;MAIT T-cell: 184.9;memory CD8 T-cell: 144.9;naive CD8 T-cell: 109.3" "Lineage enriched" "Detected in many" 7 "T-cells: 299.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.4" "Adipose subcutaneous - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 7: NK-cells - Immune response regulation" "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" SAMD11 MGC45873 ENSG00000187634 "Sterile alpha motif domain containing 11" Q96NU1 1 923923-944575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 61.3" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030110 Approved Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "HPA030110: " "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (4.11e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-2)" "unprognostic (2.42e-1)" "unprognostic (9.28e-2)" "unprognostic (6.90e-2)" "unprognostic (3.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.35e-5)" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.26e-2)" "unprognostic (1.18e-1)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Group enriched" "Detected in many" 7 "B-cells: 78.9;Hofbauer cells: 42.8;Kupffer cells: 89.4;Macrophages: 63.9;monocytes: 119.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cancer enhanced" "Detected in many" "lymphoma: 15.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 226.5;Alveolar cells type 2: 187.3;Distal enterocytes: 120.6;Glandular and luminal cells: 185.6;Intestinal goblet cells: 186.4;Salivary duct cells: 181.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.0;Club cells: 26.4;Collecting duct cells: 41.4;Gastric mucus-secreting cells: 14.9;Glandular and luminal cells: 16.7;Ionocytes: 17.9;Salivary duct cells: 27.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 15.9" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 14: Bone cancer - Transcription" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7;choroid plexus: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 44.9;Melanocytes: 50.5;Muller glia cells: 138.4;Oligodendrocyte precursor cells: 97.7;Sertoli cells: 94.0" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Brain cancer: 2.2;skin cancer: 3.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" NA NA 240000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 68: Muller glia cells - Visual perception" "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 667.9;Ductal cells: 640.1;Fibroblasts: 830.3;Hepatocytes: 2202.4;Leydig cells: 755.1;Thymic epithelial cells: 1994.0" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Cancer enhanced" "Detected in many" "liver cancer: 32.4;testis cancer: 41.8" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 7 "Fibroblasts: 712.4" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.9;Brain cancer: 15.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 116.5;Alveolar cells type 2: 122.6;Endometrial ciliated cells: 167.6;Glandular and luminal cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015076, HPA015541" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 14: Endometrium - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA015076: AB_1857298, HPA015541: " "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" SGPP2 "FLJ39004, SPP2" ENSG00000163082 "Sphingosine-1-phosphate phosphatase 2" Q8IWX5 2 222424543-222562621 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.9;Glandular and luminal cells: 110.5;Suprabasal keratinocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.56e-3)" "unprognostic (1.79e-1)" "unprognostic (8.50e-2)" "unprognostic (2.97e-2)" "unprognostic (1.24e-3)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.31e-2)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.74e-2)" "unprognostic (2.69e-2)" SH3GL3 "CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13" ENSG00000140600 "SH3 domain containing GRB2 like 3, endophilin A3" Q99963 15 83447228-83618743 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 77.2;choroid plexus: 19.4;testis: 26.5" "Group enriched" "Detected in many" 4 "Early spermatids: 467.4;Late spermatids: 1355.9;Oligodendrocytes: 1078.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 15.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039381, HPA077877" Enhanced Approved Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 14: Bone cancer - Transcription" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA039381: AB_10794635, HPA077877: AB_2686863" "unprognostic (1.10e-3)" "unprognostic (6.62e-2)" "unprognostic (4.25e-2)" "unprognostic (1.86e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-1)" "unprognostic (9.76e-2)" "unprognostic (2.26e-1)" "unprognostic (8.20e-3)" "unprognostic (2.72e-3)" "unprognostic (1.43e-6)" "unprognostic (4.42e-2)" "unprognostic (3.59e-2)" "unprognostic (2.93e-1)" "unprognostic (5.78e-4)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Group enriched" "Detected in some" 5 "Hofbauer cells: 36.7;Kupffer cells: 39.7;Macrophages: 33.3;monocytes: 16.7;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 4.0;Myeloma: 5.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Group enriched" "Detected in some" 10 "dendritic cells: 36.0;Hofbauer cells: 29.7;Kupffer cells: 70.2;Macrophages: 32.0;monocytes: 48.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Cancer enhanced" "Detected in many" "Leukemia: 18.2;Sarcoma: 15.1;thyroid cancer: 22.7" "Adipose subcutaneous - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650950 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 95.4" "Group enriched" "Detected in some" 7 "B-cells: 80.9;dendritic cells: 39.5;Plasma cells: 23.8;T-cells: 80.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 202.7;memory B-cell: 213.6;memory CD4 T-cell: 249.2;memory CD8 T-cell: 223.4;naive B-cell: 192.1;naive CD4 T-cell: 170.4;naive CD8 T-cell: 169.5;plasmacytoid DC: 203.1;T-reg: 352.4" "Group enriched" "Detected in many" 56 "B-cells: 213.6;dendritic cells: 203.1;T-cells: 352.4" "Group enriched" "Detected in some" 9 "Leukemia: 22.7;lymphoma: 66.8" "Colon - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018506 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA018506: AB_2669896" "unprognostic (4.28e-3)" "prognostic favorable (6.56e-4)" "unprognostic (8.01e-3)" "prognostic favorable (1.94e-6)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-4)" "unprognostic (1.75e-2)" "unprognostic (9.34e-3)" "prognostic favorable (8.17e-4)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (8.87e-2)" "unprognostic (6.34e-2)" SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.6;Kupffer cells: 202.1;Macrophages: 156.4;monocytes: 190.1;NK-cells: 323.6;T-cells: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Leukemia: 36.4;lymphoma: 23.9;Myeloma: 17.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Group enriched" "Detected in some" 5 "B-cells: 22.0;Late spermatids: 23.2;NK-cells: 39.8;Plasma cells: 18.2;Serous glandular cells: 12.7;T-cells: 34.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 9.2;lymphoma: 34.1" "Breast - Plasma cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 34.9;Kupffer cells: 12.3;Langerhans cells: 69.9;Macrophages: 41.4;Schwann cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 1.3;lymphoma: 2.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Fibroblasts, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 75: Myeloid cells - Innate immune response" "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 1967.1;Syncytiotrophoblasts: 699.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 68: Kidney - Mixed function" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" SLC1A1 "EAAC1, EAAT3" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 45.0;intestine: 64.7;kidney: 51.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.0;Glandular and luminal cells: 122.1;Hepatocytes: 58.4;Inhibitory neurons: 48.9;Microglial cells: 65.7;Oligodendrocyte precursor cells: 154.5;Proximal enterocytes: 95.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 14: Endometrium - Transcription regulation" "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 186.9;Cone photoreceptor cells: 81.0;Rod photoreceptor cells: 70.1" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Group enriched" "Detected in some" 5 "Brain cancer: 4.9;breast cancer: 9.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" SLC26A8 ENSG00000112053 "Solute carrier family 26 member 8" Q96RN1 6 35943516-36024868 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Differentiation, Ion transport, Meiosis, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 64.2;Excitatory neurons: 15.6;Inhibitory neurons: 11.8;Late spermatids: 10.2;Spermatocytes: 51.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.3" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Stomach - Neutrophils, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA038081 Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA038081: AB_10670653" "unprognostic (8.18e-2)" "unprognostic (1.74e-1)" "unprognostic (6.71e-2)" "unprognostic (1.31e-2)" "unprognostic (2.46e-1)" "unprognostic (7.07e-3)" "unprognostic (2.93e-1)" "unprognostic (6.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (1.85e-1)" "unprognostic (3.78e-1)" "unprognostic (4.63e-6)" "unprognostic (7.14e-2)" "unprognostic (4.24e-1)" "unprognostic (2.31e-1)" "unprognostic (5.24e-8)" SLC34A3 "FLJ38680, NPTIIc" ENSG00000198569 "Solute carrier family 34 member 3" Q8N130 9 137230757-137236555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 9.7;kidney: 13.6" "Group enriched" "Detected in some" 11 "Proximal enterocytes: 78.5;Proximal tubular cells: 22.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA023776 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA023776: AB_1857102" "unprognostic (2.69e-1)" "unprognostic (4.16e-1)" "unprognostic (9.08e-3)" "unprognostic (1.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.05e-2)" "unprognostic (9.84e-3)" "unprognostic (2.05e-2)" "unprognostic (2.20e-2)" "unprognostic (5.94e-2)" "unprognostic (1.94e-2)" "unprognostic (9.12e-2)" "unprognostic (5.80e-2)" "unprognostic (2.20e-1)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Club cells: 222.1;Distal enterocytes: 465.4;Gastric mucus-secreting cells: 191.4;Intestinal goblet cells: 261.7;Ionocytes: 217.2;Paneth cells: 187.6;Prostatic glandular cells: 326.4;Proximal enterocytes: 260.4;Respiratory ciliated cells: 403.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 27.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 74: Pancreatic cells - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 760.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.2;colorectal cancer: 7.7;Gastric cancer: 2.5" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Cholangiocyte, Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Uncertain "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nuclear membrane, Golgi apparatus" "Nucleoplasm, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" SLC5A5 NIS ENSG00000105641 "Solute carrier family 5 member 5" Q92911 19 17871945-17895174 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 163.3;salivary gland: 64.4;stomach 1: 58.8" "Cell type enriched" "Detected in some" 38 "Gastric mucus-secreting cells: 219.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.7" "Group enriched" "Detected in many" 5 "cerebellum: 5.6;hippocampal formation: 10.6;thalamus: 3.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022364, HPA049055" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: Non-specific - Unknown function" "Cluster 58: Gastric mucus-secreting cells - Digestion" "CAB022364: , HPA049055: AB_2680614" "unprognostic (2.72e-2)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (4.02e-2)" "unprognostic (2.57e-1)" "unprognostic (1.94e-2)" "unprognostic (3.07e-1)" "unprognostic (2.01e-2)" "unprognostic (3.03e-1)" "unprognostic (3.93e-2)" "unprognostic (5.51e-8)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-2)" "unprognostic (3.23e-1)" SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.0;salivary gland: 20.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 183.9;Basal respiratory cells: 111.6;Club cells: 169.1;Ionocytes: 280.1;Mucus glandular cells: 108.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 11.2" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" HPA003193 Uncertain Approved Vesicles NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 46: Non-specific - Unknown function" "Cluster 5: Bronchus - Unknown function" Vesicles "HPA003193: AB_2190122" "unprognostic (3.06e-2)" "unprognostic (3.55e-2)" "unprognostic (8.49e-2)" "unprognostic (1.00e-3)" "unprognostic (1.30e-3)" "unprognostic (1.49e-2)" "unprognostic (7.41e-3)" "unprognostic (3.67e-3)" "unprognostic (2.66e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" SLC6A20 "IMINO, SIT1, XT3, Xtrp3" ENSG00000163817 "Solute carrier family 6 member 20" Q9NP91 3 45755449-45796536 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 59.2;intestine: 24.2" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 70.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 5.2;colorectal cancer: 14.6;Gastric cancer: 11.2;pancreatic cancer: 8.0" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (1.57e-1)" "unprognostic (5.26e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-2)" "unprognostic (1.48e-1)" "unprognostic (9.43e-3)" "unprognostic (3.26e-2)" "unprognostic (4.33e-3)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.55e-5)" "unprognostic (2.87e-1)" "unprognostic (1.23e-1)" "unprognostic (7.55e-2)" "unprognostic (2.09e-2)" SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 250.9;Kupffer cells: 227.4;Macrophages: 158.7;monocytes: 228.8;Proximal enterocytes: 406.0;Proximal tubular cells: 266.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: Non-specific - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 188.4;Hofbauer cells: 108.1;Kupffer cells: 79.1;Macrophages: 128.7;Microglial cells: 226.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 20.9;liver cancer: 20.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 69: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.1;kidney: 22.1;stomach 1: 33.1;testis: 26.1" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1360.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Group enriched" "Detected in many" 5 "Bile duct cancer: 7.9;colorectal cancer: 4.1;Gastric cancer: 9.6;Kidney cancer: 9.7;liver cancer: 6.1;lung cancer: 2.4;ovarian cancer: 3.9;pancreatic cancer: 6.7;Uterine cancer: 3.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "HPA065721: AB_2685546" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (7.07e-2)" "prognostic favorable (1.49e-4)" "unprognostic (3.42e-1)" "unprognostic (1.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (8.06e-2)" "prognostic favorable (4.09e-4)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.58e-2)" "prognostic favorable (1.64e-4)" SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 92.0;Excitatory neurons: 84.8;Fibroblasts: 35.9;Inhibitory neurons: 31.7;Leydig cells: 93.2;Microglial cells: 75.7;Peritubular cells: 68.2;Theca cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 38: Neurons - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 89.7;Astrocytes: 49.0;Excitatory neurons: 56.8;Inhibitory neurons: 59.2;Oligodendrocyte precursor cells: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 41: Alveolar cells - Lung function" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.1;lymphoid tissue: 7.1;testis: 5.0" "Cell type enhanced" "Detected in some" "B-cells: 10.9;Extravillous trophoblasts: 48.7;Hofbauer cells: 17.7;Proximal enterocytes: 11.1;Syncytiotrophoblasts: 11.3" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA065955: AB_2685586" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.10e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (4.38e-2)" "unprognostic (2.03e-1)" "unprognostic (7.20e-2)" "unprognostic (3.45e-2)" "unprognostic (6.07e-2)" "unprognostic (5.80e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-5)" "unprognostic (5.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.22e-2)" "unprognostic (3.74e-3)" SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.7;Erythroid cells: 33.4;Extravillous trophoblasts: 39.0;Pancreatic endocrine cells: 37.8;Plasma cells: 22.5;Spermatocytes: 28.8;Spermatogonia: 19.3;Undifferentiated cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 44.3;Cardiomyocytes: 58.2;Excitatory neurons: 20.2;Inhibitory neurons: 20.3;Sertoli cells: 27.6;Skeletal myocytes: 32.7;Smooth muscle cells: 33.4;Thymic epithelial cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1223.0;Proximal enterocytes: 474.3;Syncytiotrophoblasts: 1720.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 228.5;Syncytiotrophoblasts: 301.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 26: NCI-H716 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" SRRM3 FLJ37078 ENSG00000177679 "Serine/arginine repetitive matrix 3" 7 76201896-76287288 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 56.0;retina: 27.2" "Group enriched" "Detected in many" 6 "Bipolar cells: 118.7;Cone photoreceptor cells: 232.6;Excitatory neurons: 137.2;Horizontal cells: 222.4;Inhibitory neurons: 141.3;Rod photoreceptor cells: 433.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 16.6" "Lung - Fibroblast_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019337 Approved "Plasma membrane,Intermediate filaments,Microtubules" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "Intermediate filaments, Microtubules" "HPA019337: AB_1848909" "unprognostic (1.65e-1)" "unprognostic (1.96e-1)" "unprognostic (8.37e-3)" "unprognostic (4.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (6.51e-2)" "unprognostic (1.89e-3)" "unprognostic (1.62e-2)" "unprognostic (5.07e-3)" "unprognostic (6.37e-2)" "unprognostic (3.73e-3)" "unprognostic (5.05e-1)" "unprognostic (2.98e-1)" "unprognostic (1.84e-1)" "unprognostic (5.15e-2)" ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643786 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 61.1;intestine: 195.9;stomach 1: 64.9" "Cell type enriched" "Detected in many" 4 "Intestinal goblet cells: 631.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 8.9;naive CD4 T-cell: 3.4" "Lineage enriched" "Detected in single" 32 "T-cells: 8.9" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 3500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 37: Intestine - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: AB_1857529" "unprognostic (4.59e-2)" "unprognostic (8.60e-3)" "unprognostic (5.32e-3)" "unprognostic (1.86e-3)" "unprognostic (6.31e-3)" "prognostic favorable (2.54e-5)" "unprognostic (1.39e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.58e-2)" "unprognostic (8.64e-3)" "unprognostic (2.81e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (5.87e-3)" "unprognostic (5.58e-2)" STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in some" "Early spermatids: 100.7;Late spermatids: 48.2;Microglial cells: 26.5;Oligodendrocyte precursor cells: 162.2" "Cancer enhanced" "Detected in many" "renal cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 22.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 33: Skin cancer - Membrane components" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 951.6;lymphoid tissue: 1343.2" "Cell type enhanced" "Detected in all" "Late spermatids: 2566.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 424.6" "Group enriched" "Detected in all" 5 "dendritic cells: 424.6;T-cells: 143.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 320000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 43: Non-specific - Cell proliferation" Cytosol "CAB010107: AB_628297, HPA068438: " "unprognostic (6.30e-2)" "unprognostic (2.40e-3)" "unprognostic (5.31e-2)" "unprognostic (7.94e-2)" "unprognostic (1.89e-1)" "unprognostic (5.02e-2)" "prognostic unfavorable (9.90e-7)" "unprognostic (9.45e-2)" "unprognostic (1.39e-2)" "unprognostic (1.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-3)" "unprognostic (1.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-2)" SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Group enriched" "Detected in many" 4 "Fibroblasts: 99.3;Inhibitory neurons: 49.1;Leydig cells: 43.0;Oligodendrocytes: 132.7;Syncytiotrophoblasts: 86.9;Theca cells: 34.8;Thymic epithelial cells: 98.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 191.9;Alveolar cells type 2: 269.3;Cardiomyocytes: 294.7;Syncytiotrophoblasts: 284.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Enzymes" "Cluster 41: Alveolar cells - Lung function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" TANC2 "DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA" ENSG00000170921 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2" Q9HCD6 17 63009556-63427699 "Disease related genes, Predicted intracellular proteins" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 588.9;Granulosa cells: 188.3;Inhibitory neurons: 385.9;Oligodendrocyte precursor cells: 614.2;Oligodendrocytes: 311.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 11.2;basal ganglia: 27.6;cerebral cortex: 22.3;hippocampal formation: 15.9;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023274 Uncertain Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA023274: AB_2199727" "unprognostic (8.37e-2)" "unprognostic (4.15e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-4)" "unprognostic (1.51e-1)" "unprognostic (4.09e-2)" "unprognostic (9.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.09e-2)" "unprognostic (5.52e-2)" "unprognostic (2.62e-1)" "unprognostic (2.69e-1)" "unprognostic (2.02e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (2.01e-1)" TARM1 ENSG00000248385 "T cell-interacting, activating receptor on myeloid cells 1" B6A8C7 19 54069895-54081365 "Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "bone marrow: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051022, HPA054401" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 44: Photoreceptor cells - Visual perception" "HPA051022: AB_2681315, HPA054401: AB_2682476" "unprognostic (1.56e-1)" TBX18 ENSG00000112837 "T-box transcription factor 18" O95935 6 84687351-84764598 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.3" "Cell type enriched" "Detected in some" 4 "Microglial cells: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006807 Supported Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "HPA006807: " "unprognostic (8.04e-2)" "unprognostic (7.06e-3)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (2.57e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-14)" "unprognostic (4.81e-5)" "unprognostic (1.86e-1)" "unprognostic (3.07e-3)" "unprognostic (1.78e-1)" TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.8;Plasma cells: 23.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 15: Non-specific - Protein binding" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" TCF23 "bHLHa24, OUT" ENSG00000163792 "Transcription factor 23" Q7RTU1 2 27149004-27156974 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 51.2;fallopian tube: 24.6;ovary: 18.5;smooth muscle: 20.4" "Group enriched" "Detected in some" 10 "Leydig cells: 10.3;Peritubular cells: 30.8;Sertoli cells: 19.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Lung - Fibroblast_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044596 Approved "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 52: Endometrial stromal cells - ECM organization" "Nuclear speckles" "HPA044596: AB_10797258" "unprognostic (1.04e-1)" "unprognostic (2.47e-3)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (3.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.70e-2)" "unprognostic (4.07e-2)" "unprognostic (3.21e-1)" "unprognostic (1.74e-2)" "unprognostic (4.08e-2)" "unprognostic (8.58e-2)" "unprognostic (2.41e-5)" "unprognostic (7.58e-3)" "unprognostic (3.01e-1)" "unprognostic (8.58e-4)" "unprognostic (2.64e-2)" TEDC2 "C16orf59, FLJ13909" ENSG00000162062 "Tubulin epsilon and delta complex 2" Q7L2K0 16 2460086-2464963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;testis: 5.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 13.7;Extravillous trophoblasts: 13.1;Spermatogonia: 37.3;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051394, HPA055389" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: RS4;11 - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Cell Junctions" "HPA051394: AB_2681465, HPA055389: AB_2732595" "unprognostic (3.23e-1)" "unprognostic (1.03e-2)" "unprognostic (2.14e-2)" "unprognostic (7.46e-3)" "unprognostic (1.27e-1)" "unprognostic (1.38e-3)" "prognostic unfavorable (2.43e-5)" "prognostic unfavorable (7.58e-4)" "unprognostic (4.04e-3)" "unprognostic (8.85e-2)" "unprognostic (3.74e-2)" "unprognostic (3.72e-2)" "unprognostic (1.16e-4)" "unprognostic (1.28e-3)" "unprognostic (1.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.03e-1)" TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 621.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 96.0;Basal squamous epithelial cells: 106.2;Breast glandular cells: 58.0;Breast myoepithelial cells: 64.1;Cytotrophoblasts: 89.6;Extravillous trophoblasts: 59.0;Squamous epithelial cells: 71.2;Suprabasal keratinocytes: 93.4;Syncytiotrophoblasts: 109.0" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 70.8" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 97.9;Endometrial stromal cells: 81.4;Leydig cells: 92.9;Pancreatic endocrine cells: 84.2;Peritubular cells: 182.6;Sertoli cells: 102.3;Smooth muscle cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020844, HPA072360" Enhanced Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Focal adhesion sites" "Vesicles, Cytosol" "CAB020844: , HPA072360: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "pituitary gland: 106.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.9;Distal tubular cells: 6.2;Excitatory neurons: 7.2;Plasma cells: 6.6;Proximal tubular cells: 7.7;Sertoli cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 53: Non-specific - mRNA processing" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 46.3;Microglial cells: 14.6;Serous glandular cells: 10.9;T-cells: 66.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 19 "Leukemia: 3.6;lymphoma: 3.1;Myeloma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.1;Excitatory neurons: 114.3;Fibroblasts: 173.9;Horizontal cells: 116.6;Inhibitory neurons: 101.6;Leydig cells: 99.8;Muller glia cells: 98.5;Proximal tubular cells: 162.8;Smooth muscle cells: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 436.6;thyroid cancer: 250.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" TIFAB ENSG00000255833 "TIFA inhibitor" Q6ZNK6 5 135444226-135452351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.6" "Cell type enhanced" "Detected in some" "dendritic cells: 11.8;Early spermatids: 4.3;Langerhans cells: 25.7;Late spermatids: 10.2;monocytes: 5.3;Schwann cells: 4.5" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "myeloid DC: 4.5;plasmacytoid DC: 13.9" "Lineage enriched" "Detected in many" 11 "dendritic cells: 13.9" "Cancer enriched" "Detected in single" 38 "Leukemia: 3.7" "Lung - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049372 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA049372: AB_2680733" "unprognostic (1.33e-2)" "unprognostic (1.09e-2)" "unprognostic (1.63e-2)" "unprognostic (1.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.98e-5)" "unprognostic (3.87e-1)" "unprognostic (3.25e-3)" "unprognostic (5.29e-2)" "unprognostic (1.09e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (9.01e-2)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 49.3;Endothelial cells: 41.5;Hofbauer cells: 73.7;Kupffer cells: 129.6;Macrophages: 89.3;monocytes: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cancer enhanced" "Detected in many" "Brain cancer: 11.8" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Proximal enterocytes: 218.0;Respiratory ciliated cells: 152.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 60.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.7;Gastric cancer: 3.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" TMEM41B KIAA0033 ENSG00000166471 "Transmembrane protein 41B" Q5BJD5 11 9280654-9314636 "Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Lipid transport, Neurogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014946 Uncertain Approved Peroxisomes NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 45: Intestine - Brush border" "Cluster 2: DU4475 - Unknown function" "Cluster 41: Alveolar cells - Lung function" Peroxisomes "HPA014946: AB_2205037" "unprognostic (1.21e-1)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.18e-6)" "unprognostic (6.18e-2)" "unprognostic (9.37e-3)" "unprognostic (4.90e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (8.18e-2)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.6;Gastric mucus-secreting cells: 172.9;Paneth cells: 149.4;Prostatic glandular cells: 377.5;Proximal enterocytes: 170.9" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 271.4" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 50: Enterocytes - Absorption" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 74.3;Kupffer cells: 45.0;Macrophages: 38.3;monocytes: 43.5;NK-cells: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 27.0;lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 23.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 2.9;Ionocytes: 3.7;Kupffer cells: 2.5;Proximal enterocytes: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3195.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3195.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Testis - Sertoli cells" CAB025635 Enhanced NA NA 14600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: BEWO - Unknown function" "Cluster 33: Macrophages - Degranulation" "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 15 "Plasma cells: 468.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cancer enriched" "Detected in some" 12 "Myeloma: 633.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" TOX "KIAA0808, TOX1" ENSG00000198846 "Thymocyte selection associated high mobility group box" O94900 8 58805412-59119147 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 52.4" "Group enriched" "Detected in many" 5 "Astrocytes: 306.5;Excitatory neurons: 194.9;Inhibitory neurons: 151.7;Oligodendrocyte precursor cells: 436.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 36.6" "Group enriched" "Detected in many" 5 "granulocytes: 21.5;NK-cells: 18.4;T-cells: 36.6" "Cancer enhanced" "Detected in many" "Leukemia: 20.9" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018322, HPA073241" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 32: Neurons - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "HPA018322: AB_1858199, HPA073241: AB_2686584" "unprognostic (7.60e-4)" "unprognostic (6.16e-3)" "unprognostic (5.65e-2)" "unprognostic (2.27e-1)" "unprognostic (9.53e-2)" "unprognostic (4.52e-1)" "unprognostic (1.22e-1)" "prognostic favorable (5.20e-4)" "unprognostic (1.46e-1)" "unprognostic (3.46e-3)" "unprognostic (6.73e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.90e-7)" "unprognostic (1.12e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" TPBG "5T4, 5T4-AG" ENSG00000146242 "Trophoblast glycoprotein" Q13641 6 82363206-82367420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 108.3;Extravillous trophoblasts: 94.8;Thymic epithelial cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010554 Enhanced Approved Nucleoplasm NA NA 310000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "HPA010554: AB_1858206" "unprognostic (3.03e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (6.68e-4)" "unprognostic (1.06e-1)" "unprognostic (4.52e-3)" "unprognostic (7.47e-3)" "unprognostic (8.55e-2)" "unprognostic (3.55e-3)" "unprognostic (8.39e-2)" "unprognostic (3.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.94e-1)" "unprognostic (3.77e-1)" "unprognostic (7.46e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (5.57e-2)" TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.4;Endometrial ciliated cells: 171.1;Respiratory ciliated cells: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 45: Non-specific - Cell proliferation" "Cluster 56: Ciliated cells - Cilium assembly" "HPA037857: AB_2675706, HPA037858: AB_10671724" "unprognostic (1.25e-1)" "unprognostic (9.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.80e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (9.04e-2)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (4.78e-3)" "unprognostic (7.48e-3)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.07e-1)" TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 9.0;Spermatocytes: 14.2;Spermatogonia: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: Non-specific - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" TRAV12-2 ENSG00000211789 "T cell receptor alpha variable 12-2" A0A075B6T6 14 21887857-21888502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 22.4" "Cell type enriched" "Detected in some" 4 "T-cells: 9.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 101.9;memory CD8 T-cell: 87.7;naive CD4 T-cell: 90.3;naive CD8 T-cell: 65.2;T-reg: 143.3" "Lineage enriched" "Detected in many" 77 "T-cells: 143.3" "Cancer enriched" "Detected in single" 328 "lymphoma: 32.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.74e-2)" "unprognostic (4.98e-3)" "unprognostic (4.75e-2)" "unprognostic (2.41e-4)" "unprognostic (2.22e-2)" "unprognostic (7.44e-2)" "unprognostic (5.23e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-3)" "unprognostic (3.69e-1)" "unprognostic (3.34e-3)" "unprognostic (9.87e-2)" "unprognostic (3.01e-2)" TRAV12-3 "TCRAV12S3, TCRAV2S2, TRAV123" ENSG00000211794 "T cell receptor alpha variable 12-3" A0A0B4J271 14 21965451-21966061 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 60.3" "Cell type enriched" "Detected in some" 4 "T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 186.5;T-reg: 256.6" "Lineage enriched" "Detected in many" 23 "T-cells: 256.6" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.62e-4)" "unprognostic (7.68e-4)" "unprognostic (5.17e-2)" "unprognostic (1.33e-3)" "unprognostic (2.32e-1)" "unprognostic (1.80e-3)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.55e-4)" "unprognostic (9.00e-3)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (4.52e-5)" "unprognostic (3.75e-1)" "unprognostic (4.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.68e-2)" TRAV13-1 ENSG00000211788 "T cell receptor alpha variable 13-1" A0A0B4J241 14 21868839-21869365 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 62.5" "Cell type enriched" "Detected in single" 29 "T-cells: 14.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 329.3" "Lineage enriched" "Detected in many" 28 "T-cells: 329.3" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.10e-3)" "unprognostic (9.80e-3)" "unprognostic (1.60e-2)" "unprognostic (3.04e-3)" "unprognostic (5.71e-2)" "unprognostic (3.30e-5)" "unprognostic (7.68e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (7.16e-5)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.20e-2)" "unprognostic (5.59e-2)" TRAV13-2 ENSG00000211791 "T cell receptor alpha variable 13-2" A0A0B4J235 14 21918188-21918756 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "lymphoid tissue: 51.7" "Cell type enhanced" "Detected in some" "NK-cells: 2.0;Prostatic glandular cells: 1.8;T-cells: 6.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "MAIT T-cell: 32.9;memory CD4 T-cell: 94.0;memory CD8 T-cell: 57.3;naive CD4 T-cell: 101.8;naive CD8 T-cell: 114.1;T-reg: 114.8" "Lineage enriched" "Detected in many" 53 "T-cells: 114.8" "Group enriched" "Detected in some" 4 "lymphoma: 2.8;Rhabdoid: 1.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.15e-3)" "unprognostic (1.47e-2)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" "unprognostic (5.58e-1)" "unprognostic (4.38e-4)" "unprognostic (1.08e-1)" "unprognostic (6.47e-2)" "unprognostic (2.85e-2)" "unprognostic (4.16e-2)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (3.66e-4)" "unprognostic (1.52e-1)" "unprognostic (9.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.77e-2)" TRAV14DV4 "hADV14S1, TCRAV6S1-hDV104S1, TRAV14/DV4" ENSG00000211792 "T cell receptor alpha variable 14/delta variable 4" A0A0A6YYC5 14 21924063-21924651 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 25.7" "Cell type enriched" "Detected in single" 10 "T-cells: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 38.2;memory CD8 T-cell: 78.1;naive CD4 T-cell: 30.7;naive CD8 T-cell: 122.3;T-reg: 42.6" "Lineage enriched" "Detected in single" 176 "T-cells: 122.3" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.82e-3)" "unprognostic (1.00e-2)" "unprognostic (1.43e-1)" "unprognostic (3.06e-3)" "unprognostic (3.00e-5)" "unprognostic (2.52e-1)" "unprognostic (7.61e-4)" "unprognostic (3.77e-1)" "unprognostic (2.82e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-5)" "unprognostic (3.01e-1)" "unprognostic (4.17e-2)" "unprognostic (2.90e-1)" "unprognostic (1.60e-2)" TRAV16 "TCRAV16S1, TCRAV9S1" ENSG00000211796 "T cell receptor alpha variable 16" A0A0A6YYK6 14 21990496-21990938 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 39.8" "Cell type enriched" "Detected in some" 5 "T-cells: 5.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 48.0;T-reg: 58.0" "Lineage enriched" "Detected in single" 164 "T-cells: 58.0" "Cancer enriched" "Detected in some" 5 "lymphoma: 8.3" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.93e-2)" "unprognostic (1.06e-4)" "unprognostic (6.22e-3)" "unprognostic (3.67e-3)" "unprognostic (1.01e-4)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (2.79e-2)" "unprognostic (6.94e-4)" "unprognostic (5.25e-2)" "unprognostic (2.33e-1)" "unprognostic (5.27e-5)" "unprognostic (1.55e-1)" "unprognostic (3.91e-2)" "unprognostic (4.01e-1)" "unprognostic (2.07e-3)" TRAV17 "TCRAV17S1, TCRAV3S1" ENSG00000211797 "T cell receptor alpha variable 17" A0A0B4J275 14 21997539-21998168 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in single" 8 "T-cells: 7.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 81.4;memory CD8 T-cell: 63.7;naive CD4 T-cell: 61.8;naive CD8 T-cell: 53.2;T-reg: 116.3" "Lineage enriched" "Detected in single" 226 "T-cells: 116.3" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (8.22e-4)" "unprognostic (4.50e-3)" "unprognostic (1.37e-3)" "unprognostic (2.06e-2)" "unprognostic (2.72e-6)" "unprognostic (6.44e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-2)" "unprognostic (1.67e-3)" "unprognostic (8.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (8.43e-3)" "unprognostic (8.53e-2)" "unprognostic (2.21e-1)" TRAV19 "TCRAV12S1, TCRAV19S1" ENSG00000211799 "T cell receptor alpha variable 19" A0A0A6YYK7 14 22007512-22008181 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 36.8" "Cell type enriched" "Detected in single" 8 "T-cells: 3.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "memory CD4 T-cell: 17.8;memory CD8 T-cell: 45.6;naive CD4 T-cell: 23.2;naive CD8 T-cell: 24.5;T-reg: 23.9" "Lineage enriched" "Detected in single" 173 "T-cells: 45.6" "Cancer enriched" "Detected in single" 128 "Leukemia: 36.7" "Adipose visceral - T-cells, Lung - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (5.04e-3)" "unprognostic (2.11e-2)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (1.52e-1)" "unprognostic (2.95e-4)" "unprognostic (2.15e-3)" "unprognostic (1.50e-1)" "unprognostic (4.92e-2)" "unprognostic (2.99e-3)" "unprognostic (1.15e-1)" "unprognostic (3.41e-1)" "unprognostic (3.79e-2)" "unprognostic (1.22e-1)" "unprognostic (7.40e-2)" "unprognostic (1.18e-1)" "unprognostic (4.33e-3)" TRAV21 ENSG00000211801 "T cell receptor alpha variable 21" A0A0B4J279 14 22052514-22053056 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 63.2" "Cell type enriched" "Detected in some" 6 "T-cells: 24.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 220.5;memory CD8 T-cell: 233.5;naive CD4 T-cell: 198.6;naive CD8 T-cell: 204.8;T-reg: 391.9" "Lineage enriched" "Detected in many" 76 "T-cells: 391.9" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.53e-4)" "unprognostic (1.03e-2)" "unprognostic (3.94e-3)" "unprognostic (3.69e-4)" "unprognostic (1.74e-1)" "unprognostic (1.22e-3)" "unprognostic (4.86e-3)" "unprognostic (2.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" "unprognostic (4.20e-2)" "unprognostic (9.80e-2)" "unprognostic (4.53e-3)" "unprognostic (3.13e-1)" "unprognostic (2.96e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" TRAV25 "TCRAV25S1, TCRAV32S1" ENSG00000211806 "T cell receptor alpha variable 25" A0A0B4J276 14 22112347-22113031 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 15.2" "Cell type enriched" "Detected in single" 5 "T-cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 63 "memory CD4 T-cell: 33.5;memory CD8 T-cell: 20.9;naive CD4 T-cell: 32.6;naive CD8 T-cell: 22.5;T-reg: 49.4" "Lineage enriched" "Detected in single" 404 "T-cells: 49.4" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Breast - T-cells, Lung - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (9.50e-3)" "unprognostic (1.49e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-5)" "unprognostic (6.65e-3)" "unprognostic (7.53e-3)" "unprognostic (7.30e-3)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (9.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (3.74e-1)" TRAV26-1 ENSG00000211807 "T cell receptor alpha variable 26-1" A0A087WT03 14 22123318-22124285 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 14.0" "Cell type enriched" "Detected in single" 32 "T-cells: 3.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 37.4;naive CD4 T-cell: 39.7;T-reg: 55.8" "Lineage enriched" "Detected in single" 69 "T-cells: 55.8" "Not detected" "Not detected" "Lung - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.36e-3)" "unprognostic (1.33e-5)" "unprognostic (1.21e-2)" "unprognostic (3.60e-2)" "unprognostic (1.50e-3)" "unprognostic (1.08e-2)" "unprognostic (4.89e-2)" "unprognostic (1.99e-1)" "unprognostic (4.67e-4)" "unprognostic (3.93e-3)" "unprognostic (3.28e-1)" "unprognostic (4.01e-5)" "unprognostic (1.63e-1)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-2)" TRAV29DV5 TRAV29/DV5 ENSG00000211810 "T cell receptor alpha variable 29/delta variable 5" P04437 14 22163238-22163870 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 26.6" "Cell type enriched" "Detected in some" 10 "T-cells: 13.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "memory CD4 T-cell: 99.2;memory CD8 T-cell: 126.3;naive CD4 T-cell: 105.5;naive CD8 T-cell: 66.4;T-reg: 123.9" "Lineage enriched" "Detected in single" 129 "T-cells: 126.3" "Not detected" "Not detected" "Adipose visceral - T-cells, Lung - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 2: T-cells - T-cell receptor" "unprognostic (7.25e-4)" "unprognostic (3.20e-3)" "unprognostic (4.50e-2)" "unprognostic (8.49e-4)" "unprognostic (3.24e-3)" "unprognostic (9.16e-2)" "unprognostic (2.73e-1)" "unprognostic (4.17e-3)" "unprognostic (4.47e-2)" "unprognostic (3.81e-1)" "unprognostic (1.03e-1)" "unprognostic (5.11e-4)" "unprognostic (7.53e-2)" "unprognostic (4.69e-2)" "unprognostic (9.86e-2)" "unprognostic (7.28e-2)" TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.1" "Cell type enriched" "Detected in some" 5 "T-cells: 6.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.8;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.2;naive CD8 T-cell: 47.8;T-reg: 112.7" "Lineage enriched" "Detected in single" 144 "T-cells: 112.7" "Group enriched" "Detected in some" 26 "Bone cancer: 15.8;Leukemia: 11.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.32e-3)" "unprognostic (4.61e-4)" "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (7.75e-2)" "unprognostic (8.35e-4)" "unprognostic (8.65e-3)" "unprognostic (4.31e-3)" "unprognostic (2.88e-3)" "unprognostic (4.24e-3)" "unprognostic (5.27e-2)" "unprognostic (3.35e-1)" "unprognostic (1.91e-4)" "unprognostic (1.67e-1)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" TRAV5 ENSG00000211779 "T cell receptor alpha variable 5" A0A0B4J249 14 21749178-21749705 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.9" "Cell type enriched" "Detected in some" 4 "T-cells: 5.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 52 "MAIT T-cell: 24.7;memory CD4 T-cell: 49.5;memory CD8 T-cell: 77.3;naive CD4 T-cell: 39.9;naive CD8 T-cell: 74.0;T-reg: 81.4" "Lineage enriched" "Detected in many" 73 "T-cells: 81.4" "Group enriched" "Detected in some" 9 "Leukemia: 34.9;lymphoma: 12.8" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.04e-3)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.69e-2)" "unprognostic (6.26e-5)" "unprognostic (3.58e-1)" "unprognostic (8.15e-2)" "unprognostic (5.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-2)" "unprognostic (8.38e-6)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.70e-2)" TRAV8-4 ENSG00000211790 "T cell receptor alpha variable 8-4" P01737 14 21894433-21895030 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 20.8" "Cell type enriched" "Detected in single" 11 "T-cells: 5.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 184.9;memory CD8 T-cell: 101.6;naive CD4 T-cell: 154.6;naive CD8 T-cell: 74.5;T-reg: 235.1" "Lineage enriched" "Detected in many" 49 "T-cells: 235.1" "Cancer enriched" "Detected in some" 5 "Leukemia: 7.5" "Adipose visceral - T-cells, Lung - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.41e-4)" "unprognostic (1.74e-3)" "unprognostic (2.29e-2)" "unprognostic (1.14e-4)" "unprognostic (3.47e-4)" "unprognostic (5.06e-2)" "unprognostic (1.42e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-3)" "unprognostic (1.42e-1)" "unprognostic (3.80e-2)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" TRAV9-2 ENSG00000211793 "T cell receptor alpha variable 9-2" A0A087WT02 14 21941128-21941657 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in single" 8 "T-cells: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 178.3;naive CD4 T-cell: 172.2;T-reg: 350.8" "Lineage enriched" "Detected in many" 78 "T-cells: 350.8" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.02e-3)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (1.25e-4)" "unprognostic (1.14e-5)" "unprognostic (1.37e-2)" "unprognostic (2.23e-2)" "unprognostic (5.98e-4)" "unprognostic (9.53e-3)" "unprognostic (1.92e-1)" "unprognostic (2.51e-1)" "unprognostic (9.00e-4)" "unprognostic (2.49e-1)" "unprognostic (4.28e-2)" "unprognostic (3.38e-1)" "unprognostic (2.56e-2)" TRBV12-4 "TCRBV12S4, TCRBV8S2A1T, TRBV124" ENSG00000276953 "T cell receptor beta variable 12-4" A0A0B4J2E0 7 142563740-142564245 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "lymphoid tissue: 110.3" "Cell type enriched" "Detected in single" 22 "T-cells: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 32 "memory CD4 T-cell: 28.6;memory CD8 T-cell: 38.8;naive CD4 T-cell: 39.7;naive CD8 T-cell: 33.7;T-reg: 54.4" "Lineage enriched" "Detected in single" 68 "T-cells: 54.4" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.97e-4)" "unprognostic (1.20e-4)" "unprognostic (7.96e-2)" "unprognostic (1.32e-3)" "unprognostic (3.96e-4)" "unprognostic (1.20e-2)" "unprognostic (5.27e-3)" "unprognostic (1.50e-2)" "unprognostic (9.59e-4)" "unprognostic (1.53e-2)" "unprognostic (1.25e-1)" "unprognostic (8.22e-5)" "unprognostic (4.32e-2)" "unprognostic (5.32e-3)" "unprognostic (1.44e-1)" "unprognostic (5.08e-3)" TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 1.8;T-cells: 5.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Cancer enriched" "Detected in single" 5 "Leukemia: 3.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" TRBV4-1 "BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41" ENSG00000211710 "T cell receptor beta variable 4-1" A0A577 7 142313184-142313666 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 115.0" "Group enriched" "Detected in some" 6 "Erythroid cells: 4.2;T-cells: 11.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 176.7" "Lineage enriched" "Detected in many" 89 "T-cells: 176.7" "Cancer enriched" "Detected in single" 71 "lymphoma: 11.0" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.58e-4)" "unprognostic (3.14e-3)" "unprognostic (1.49e-2)" "unprognostic (5.74e-4)" "unprognostic (1.88e-1)" "unprognostic (6.43e-3)" "unprognostic (5.89e-2)" "unprognostic (2.96e-2)" "unprognostic (6.43e-3)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (6.71e-5)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.67e-2)" "unprognostic (8.99e-2)" TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 14.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in some" 7 "Hofbauer cells: 916.9" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;Leukemia: 2.4;testis cancer: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Sebaceous gland cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" TRGV9 "TCRGV9, V2" ENSG00000211695 "T cell receptor gamma variable 9" Q99603 7 38317017-38318861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9;prostate: 5.5" "Group enriched" "Detected in some" 7 "NK-cells: 26.1;T-cells: 31.6" "Cancer enriched" "Detected in single" 126 "prostate cancer: 13.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "gdT-cell: 426.5" "Lineage enriched" "Detected in many" 13 "T-cells: 426.5" "Cancer enriched" "Detected in some" 20 "prostate cancer: 62.3" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - Prostate glandular cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 19: Lung - Lung function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (3.98e-3)" "unprognostic (4.43e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (2.41e-1)" "unprognostic (6.60e-4)" "unprognostic (1.29e-1)" "unprognostic (4.95e-1)" TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407935-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 42.0" "Group enriched" "Detected in some" 28 "Early spermatids: 264.9;Late spermatids: 129.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.9" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA054908 Approved Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 49: Early spermatids - Spermatogenesis" Vesicles "HPA054908: AB_2682638" "prognostic favorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 5.2;Alveolar cells type 2: 8.3;Extravillous trophoblasts: 16.9;Horizontal cells: 10.9;Spermatogonia: 14.9" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "testis cancer: 76.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 6: BEWO - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" TTC34 ENSG00000215912 "Tetratricopeptide repeat domain 34" A8MYJ7 1 2635976-2801717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.8;Early spermatids: 23.6;Late spermatids: 25.4;Respiratory ciliated cells: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA066832 Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 56: Ciliated cells - Cilium assembly" "HPA066832: AB_2685731" "unprognostic (1.45e-4)" "unprognostic (5.00e-2)" "unprognostic (7.09e-2)" "unprognostic (3.25e-2)" "unprognostic (3.55e-2)" "unprognostic (3.52e-2)" "unprognostic (1.70e-1)" "unprognostic (3.93e-2)" "unprognostic (1.98e-3)" "unprognostic (1.71e-1)" "unprognostic (3.69e-3)" "unprognostic (9.93e-2)" "unprognostic (1.95e-1)" "unprognostic (9.16e-3)" "unprognostic (2.43e-1)" "unprognostic (1.46e-2)" "unprognostic (2.68e-4)" TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134250 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.4;lymphoid tissue: 15.8" "Group enriched" "Detected in many" 6 "NK-cells: 224.8;T-cells: 63.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 152.3" "Group enriched" "Detected in many" 19 "NK-cells: 152.3;T-cells: 54.8" "Cancer enhanced" "Detected in many" "Myeloma: 4.6" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078636 Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA078636: " "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in some" "Early spermatids: 19.8;Late spermatids: 14.7;Skeletal myocytes: 20.8;Spermatocytes: 20.0" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 47: Retina - Visual perception" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Alveolar cells type 1, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" NA NA 24000 "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 4: Platelets - Platelet activation" "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 28.2;Fibroblasts: 84.2;Granulosa cells: 44.9;Leydig cells: 118.7;Peritubular cells: 23.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cancer enriched" "Detected in many" 6 "testis cancer: 62.2" "Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "stomach 1: 619.2" "Group enriched" "Detected in many" 4 "Club cells: 180.4;Distal enterocytes: 581.0;Gastric mucus-secreting cells: 618.9;Intestinal goblet cells: 235.4;Paneth cells: 367.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gastric cancer: 20.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 884.4;Kupffer cells: 409.6;Langerhans cells: 148.0;Macrophages: 445.0" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Cancer enriched" "Detected in single" 29 "Leukemia: 2.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000, HPA072756" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776, HPA072756: " "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 86.4;dendritic cells: 66.9;Hofbauer cells: 142.9;Kupffer cells: 133.6;Macrophages: 108.5;monocytes: 203.6;NK-cells: 98.3;T-cells: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Group enriched" "Detected in many" 37 "Leukemia: 64.4;lymphoma: 65.1;Myeloma: 43.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 98.1;Extravillous trophoblasts: 130.8;Granulosa cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "HPA029128: AB_10603460" "unprognostic (4.27e-2)" "unprognostic (5.05e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.13e-6)" "unprognostic (7.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-2)" "unprognostic (6.97e-3)" "unprognostic (2.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.36e-3)" "unprognostic (5.33e-3)" "unprognostic (6.20e-2)" "unprognostic (5.02e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (3.64e-2)" WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 293.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells, Lung - Alveolar cells type 1, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 45: Non-specific - Cell proliferation" "Cluster 12: Non-specific - Chromatin organization" Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.4;Basal keratinocytes: 2.4;Basal squamous epithelial cells: 4.0;Distal tubular cells: 3.1;Salivary duct cells: 3.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.4;head and neck cancer: 3.0" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 16.1;Basal keratinocytes: 30.7;Basal squamous epithelial cells: 37.4;Club cells: 37.4;Respiratory ciliated cells: 17.1;Squamous epithelial cells: 18.9;Suprabasal keratinocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 76.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.5;Astrocytes: 157.2;Glandular and luminal cells: 140.1;Mucus glandular cells: 105.1;Serous glandular cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1715.4;Plasma cells: 2575.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 662.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: Non-specific - Transcription" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" YTHDF2 "CAHL, HGRG8, NY-REN-2" ENSG00000198492 "YTH N6-methyladenosine RNA binding protein 2" Q9Y5A9 1 28736621-28769775 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Immunity, Innate immunity, Mitosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 274.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030063, HPA054080, HPA059621" Approved Enhanced "Cytosol,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - mRNA processing" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Cytosol "Cytoplasmic bodies" "HPA030063: AB_2732453, HPA054080: AB_2682371, HPA059621: AB_2684084" "unprognostic (8.75e-2)" "unprognostic (1.90e-2)" "unprognostic (4.66e-3)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.14e-9)" "unprognostic (1.75e-2)" "unprognostic (4.82e-2)" "unprognostic (4.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.11e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-1)" "unprognostic (6.38e-2)" "unprognostic (9.29e-2)" "unprognostic (6.97e-3)" ZDHHC19 MGC33345 ENSG00000163958 "Zinc finger DHHC-type palmitoyltransferase 19" Q8WVZ1 3 196197452-196211437 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 50.1" "Group enriched" "Detected in some" 19 "Early spermatids: 290.2;Late spermatids: 822.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "eosinophil: 1.2;memory B-cell: 2.5;naive B-cell: 2.4;neutrophil: 1.5" "Group enriched" "Detected in many" 20 "B-cells: 2.5;granulocytes: 1.5" "Not detected" "Not detected" "Heart muscle - Neutrophils, Lung - Neutrophil_2, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 37: B-cells - Transcription" "Cluster 74: Testis - Spermatogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" "unprognostic (1.15e-1)" "unprognostic (7.50e-4)" "unprognostic (2.87e-3)" "unprognostic (6.72e-3)" "unprognostic (3.79e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (3.66e-3)" "unprognostic (4.63e-2)" "unprognostic (6.52e-2)" "unprognostic (2.86e-2)" "unprognostic (3.46e-7)" "unprognostic (8.05e-4)" "unprognostic (4.71e-1)" "unprognostic (7.08e-3)" "unprognostic (4.28e-2)" ZFYVE9 "MADHIP, PPP1R173, SARA, SMADIP" ENSG00000157077 "Zinc finger FYVE-type containing 9" O95405 1 52142089-52348671 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 158.9;Oligodendrocyte precursor cells: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017702, HPA065852, HPA065862" Approved Enhanced Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 38: Non-specific - mRNA processing" "Cluster 37: Neurons - Neuronal signaling" "Vesicles, Cytosol" "CAB017702: AB_1128462, HPA065852: AB_2685568, HPA065862: AB_2685570" "unprognostic (5.05e-2)" "unprognostic (4.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-3)" "unprognostic (6.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (2.47e-2)" "unprognostic (5.36e-2)" "unprognostic (1.17e-3)" "unprognostic (2.14e-1)" "unprognostic (3.69e-1)" "unprognostic (1.99e-3)" "unprognostic (1.73e-2)" ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 101.2;Basal squamous epithelial cells: 56.2;Serous glandular cells: 49.7;Squamous epithelial cells: 159.8;Suprabasal keratinocytes: 198.8;Syncytiotrophoblasts: 69.0" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 15.1;head and neck cancer: 8.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883572-29057488 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 488.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)"