Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.6;Fibroblasts: 123.0;Hepatocytes: 86.4;Inhibitory neurons: 76.1;Langerhans cells: 57.8;Microglial cells: 91.2;Schwann cells: 70.7;Theca cells: 55.3" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;lymphoma: 3.1;pancreatic cancer: 2.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.7;Fibroblasts: 92.7;Inhibitory neurons: 71.6;Leydig cells: 96.7;Microglial cells: 221.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.9;Fibroblasts: 204.1;Leydig cells: 99.8;Muller glia cells: 80.2" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.4;thyroid cancer: 48.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 348.6;Hepatocytes: 965.9;Proximal tubular cells: 592.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Skin - Sebaceous gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 9 "Adipocytes: 579.9;Endothelial cells: 700.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.7;Brain cancer: 2.0;Leukemia: 1.5;Neuroblastoma: 2.1;skin cancer: 2.7" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.0;Endothelial cells: 140.5;Extravillous trophoblasts: 192.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Enzymes" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 83.5;Endothelial cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111479 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 148.0" "Group enriched" "Detected in some" 4 "Astrocytes: 55.4;Inhibitory neurons: 44.6" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "Neuroblastoma: 33.4" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 63: Astrocytes - Nervous system maintenance" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133070929-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 38.4" "Group enriched" "Detected in some" 7 "Excitatory neurons: 24.9;Horizontal cells: 24.4;Inhibitory neurons: 24.1;Oligodendrocyte precursor cells: 27.9" "Cancer enriched" "Detected in single" 13 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.9" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 14: Bone cancer - Transcription" "Cluster 37: Neurons - Neuronal signaling" "HPA042773: AB_10794764" "unprognostic (8.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (1.09e-2)" "unprognostic (7.51e-3)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.66e-1)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.5;kidney: 20.3;urinary bladder: 42.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.1;Club cells: 126.1;Collecting duct cells: 102.4;Glandular and luminal cells: 56.6;Ionocytes: 160.0;Respiratory ciliated cells: 125.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 66.3" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 5: Bronchus - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 399.4;Alveolar cells type 1: 207.5;Alveolar cells type 2: 288.4;Endothelial cells: 221.8;Microglial cells: 101.2;Smooth muscle cells: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.7;lung cancer: 11.1;pancreatic cancer: 7.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 6 "Adipocytes: 567.1;Endothelial cells: 303.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 12.4;thyroid cancer: 14.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 77.2;Cardiomyocytes: 43.6;Early spermatids: 95.1;Endothelial cells: 74.2;Extravillous trophoblasts: 54.4;Late spermatids: 71.0;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 7 "Hofbauer cells: 2459.1;Kupffer cells: 1902.8;Langerhans cells: 1685.0;Macrophages: 1457.6;monocytes: 3085.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Cancer enriched" "Detected in some" 28 "Leukemia: 77.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Intellectual disability, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 232.2;Proximal tubular cells: 331.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" AKAIN1 C18orf42 ENSG00000231824 "A-kinase anchor inhibitor 1" P0CW23 18 5142911-5197503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.2;brain: 22.9" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.7;Neuroblastoma: 2.9" "Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" HPA049365 Uncertain NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 37: Neurons - Neuronal signaling" "HPA049365: AB_2680729" "unprognostic (4.86e-1)" "unprognostic (1.49e-3)" "unprognostic (7.05e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 388.0;Cholangiocytes: 196.3;Distal enterocytes: 190.9;Gastric mucus-secreting cells: 499.0;Proximal enterocytes: 373.1;Suprabasal keratinocytes: 540.4" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 2640.5;liver cancer: 687.1" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 136.1;Kupffer cells: 27.4;Prostatic glandular cells: 62.5;Squamous epithelial cells: 51.9;Suprabasal keratinocytes: 29.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Group enriched" "Detected in some" 18 "breast cancer: 7.4;head and neck cancer: 4.5" "Pancreas - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 41: Alveolar cells - Lung function" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1312.6;granulocytes: 632.3;Hofbauer cells: 501.4;Langerhans cells: 421.8;Macrophages: 563.9;NK-cells: 345.3;T-cells: 308.1" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Group enriched" "Detected in many" 6 "Leukemia: 131.8;lymphoma: 164.0;Myeloma: 44.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 157.4" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Myeloma: 63.1" "Breast - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Skeletal myocytes, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 195.6;Cone photoreceptor cells: 55.1;Erythroid cells: 169.1;Horizontal cells: 85.9;Inhibitory neurons: 173.2;Skeletal myocytes: 223.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Cancer enhanced" "Detected in many" "Leukemia: 42.9;Sarcoma: 29.4" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Erythroid cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 51.7;Fibroblasts: 35.2;Leydig cells: 37.5;Muller glia cells: 50.3;Peritubular cells: 54.0;Serous glandular cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 144.3;intestine: 293.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 55.0;Cholangiocytes: 173.2;Enteroendocrine cells: 42.1;Intestinal goblet cells: 128.1;Paneth cells: 56.4;Proximal enterocytes: 131.4;Undifferentiated cells: 48.0" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 30.4;Kidney cancer: 24.9" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 70: Basal prostatic cells - Lipid metabolism" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5376.8;Ductal cells: 3505.5;Pancreatic endocrine cells: 3402.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 19.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.7;Breast myoepithelial cells: 6.2;Fibroblasts: 3.0;Oligodendrocyte precursor cells: 5.8;Pancreatic endocrine cells: 10.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 43.5" "Heart muscle - Fibroblasts, Pancreas - Beta cells" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 830.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Cancer enhanced" "Detected in many" "Brain cancer: 65.9;Leukemia: 75.8;liver cancer: 82.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Macrophages" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4323.7;Leydig cells: 2033.2;Melanocytes: 1367.2;Peritubular cells: 1126.1;Serous glandular cells: 724.4" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 4 "breast cancer: 69.2;prostate cancer: 99.4;skin cancer: 182.0" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 8379.2;Hofbauer cells: 5636.7;Leydig cells: 2655.2;Melanocytes: 3312.6;Muller glia cells: 8525.9;Peritubular cells: 4801.9;Proximal tubular cells: 6176.1;Theca cells: 8535.1" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 529.4" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 12: Non-specific - Chromatin organization" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 7945.2" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 48 "liver cancer: 169.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.7;Granulosa cells: 102.3;Hepatocytes: 247.1;Prostatic glandular cells: 470.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "prostate cancer: 92.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 73: Prostatic glandular cells - Transcription" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 31.5;Endothelial cells: 31.1;Horizontal cells: 16.0;Microglial cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 5 "Adipocytes: 62.8;Endothelial cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 1.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" ARNT2 "bHLHe1, KIAA0307" ENSG00000172379 "Aryl hydrocarbon receptor nuclear translocator 2" Q9HBZ2 15 80404350-80597933 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 128.0" "Group enriched" "Detected in many" 4 "Astrocytes: 203.1;Excitatory neurons: 202.1;Inhibitory neurons: 294.7;Microglial cells: 95.8;Oligodendrocyte precursor cells: 222.9;Oligodendrocytes: 129.2" "Cancer enhanced" "Detected in all" "glioma: 27.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 25.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001056, CAB005081" Enhanced Supported Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 56: Neurons - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "CAB005081: AB_2243005, HPA001056: AB_1845042" "unprognostic (2.04e-3)" "unprognostic (8.32e-2)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (5.65e-2)" "unprognostic (2.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.74e-2)" "unprognostic (3.00e-1)" "prognostic favorable (1.46e-6)" "unprognostic (2.20e-1)" "prognostic favorable (7.51e-4)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (3.39e-1)" "unprognostic (3.62e-2)" ATCAY BNIP-H ENSG00000167654 "ATCAY kinesin light chain interacting caytaxin" Q86WG3 19 3879864-3928082 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 46.6;pituitary gland: 25.6;retina: 17.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 93.3;Excitatory neurons: 66.0;Horizontal cells: 81.4;Inhibitory neurons: 80.2;Oligodendrocyte precursor cells: 90.0" "Cancer enriched" "Detected in some" 8 "glioma: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 34.4" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017755 Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "HPA017755: AB_2669655" "unprognostic (7.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.63e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" "unprognostic (3.05e-2)" "unprognostic (4.89e-2)" "unprognostic (9.83e-4)" "unprognostic (7.22e-2)" "unprognostic (8.78e-3)" "unprognostic (1.78e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-2)" "unprognostic (2.67e-1)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.8;Basal squamous epithelial cells: 90.5;Inhibitory neurons: 103.1;NK-cells: 137.8;Suprabasal keratinocytes: 77.0;T-cells: 295.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "Bone cancer: 18.1;Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2;stomach 1: 18.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.0;Exocrine glandular cells: 77.3;Gastric mucus-secreting cells: 35.8;Intestinal goblet cells: 42.2;Proximal enterocytes: 161.0;Undifferentiated cells: 43.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 13.2;colorectal cancer: 15.5;Gastric cancer: 5.5;pancreatic cancer: 5.4" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "HPA029732: AB_10599615, HPA029733: AB_10600422" "unprognostic (5.96e-2)" "unprognostic (6.41e-3)" "unprognostic (5.82e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.16e-1)" "unprognostic (6.23e-3)" "unprognostic (4.97e-4)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-7)" "unprognostic (5.20e-2)" "unprognostic (2.24e-2)" "unprognostic (9.04e-3)" "unprognostic (4.27e-2)" BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.0;lymphoid tissue: 141.5" "Cell type enhanced" "Detected in many" "granulocytes: 737.3;Langerhans cells: 1603.7;monocytes: 693.9;Proximal enterocytes: 883.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 209.0;naive B-cell: 159.9" "Group enriched" "Detected in all" 13 "B-cells: 209.0;T-cells: 83.6" "Cancer enhanced" "Detected in many" "lymphoma: 122.5" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "monocytes: 36.6;Oligodendrocyte precursor cells: 55.8;Plasma cells: 21.8;Serous glandular cells: 72.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Mitotic cells (Lung), Pancreas - Macrophages, Skin - Mitotic cells (Skin), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 159.6;Alveolar cells type 2: 120.0;Basal keratinocytes: 110.4;Basal squamous epithelial cells: 63.6;Distal enterocytes: 66.9;Suprabasal keratinocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 25.6" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 61: Liver - Metabolism" "Cluster 41: Alveolar cells - Lung function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 71.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 15.4;Fibroblasts: 11.3;Microglial cells: 25.5;Pancreatic endocrine cells: 39.5;Skeletal myocytes: 8.9;Smooth muscle cells: 23.3" "Cancer enhanced" "Detected in many" "lung cancer: 2.8" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.3;pons: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.8" "Liver - Hepatic stellate cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 40: Non-specific - Enzymes" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Leydig cells: 91.9;Microglial cells: 224.4;Peritubular cells: 69.0;Thymic epithelial cells: 79.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" BNIP5 "C6orf222, DKFZp779B1540" ENSG00000189325 "BCL2 interacting protein 5" P0C671 6 36315761-36336888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 24.7" "Group enriched" "Detected in some" 4 "Distal enterocytes: 102.4;Enteroendocrine cells: 48.4;Exocrine glandular cells: 64.4;Gastric mucus-secreting cells: 28.6;Intestinal goblet cells: 92.1;Paneth cells: 68.8;Proximal enterocytes: 84.4;Undifferentiated cells: 32.3" "Group enriched" "Detected in some" 19 "colorectal cancer: 8.7;pancreatic cancer: 5.1;stomach cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.5" "Colon - Colon enterocytes, Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA038407, HPA058189" Uncertain Approved Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Cytosol "HPA038407: AB_10669644, HPA058189: AB_2683634" "unprognostic (1.97e-5)" "unprognostic (5.46e-3)" "unprognostic (3.93e-1)" "unprognostic (1.49e-1)" "unprognostic (7.52e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (6.75e-2)" "unprognostic (3.04e-2)" "unprognostic (4.55e-2)" "unprognostic (3.16e-2)" "unprognostic (3.98e-1)" "unprognostic (1.66e-4)" BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 167.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 45: Non-specific - Cell proliferation" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" BRS3 "BB3, BB3R, BBR3" ENSG00000102239 "Bombesin receptor subtype 3" P32247 X 136487947-136493780 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "epididymis: 25.7" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 2.1;Pancreatic endocrine cells: 5.2;Spermatogonia: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "hypothalamus: 6.1" "Low region specificity" "Detected in many" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 26: NCI-H716 - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.07e-1)" "unprognostic (1.79e-2)" "unprognostic (3.73e-6)" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (5.59e-2)" BTBD11 "ABTB2B, FLJ33957" ENSG00000151136 "BTB domain containing 11" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 100.3" "Cell type enriched" "Detected in many" 8 "Inhibitory neurons: 261.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Keratinocyte (other), Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA055898: AB_2682964, HPA061334: " "unprognostic (3.40e-2)" "unprognostic (4.06e-1)" "unprognostic (2.37e-1)" "unprognostic (7.85e-2)" "unprognostic (8.78e-3)" "unprognostic (4.82e-2)" "unprognostic (3.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-8)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (9.07e-3)" C11orf53 MGC50104 ENSG00000150750 "Chromosome 11 open reading frame 53" Q8IXP5 11 111245726-111286401 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 3.4;testis: 5.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.5;Early spermatids: 53.3;Exocrine glandular cells: 12.8;Ionocytes: 9.0;Late spermatids: 7.8;Respiratory ciliated cells: 9.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.6" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA056128, HPA073101" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 56: Neurons - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Nucleoplasm Vesicles "HPA056128: AB_2683046, HPA073101: " "unprognostic (3.51e-2)" "unprognostic (3.60e-2)" "unprognostic (4.84e-2)" "unprognostic (5.84e-2)" "unprognostic (1.94e-1)" "unprognostic (8.07e-3)" "unprognostic (5.60e-3)" "unprognostic (3.09e-1)" "unprognostic (2.50e-1)" "unprognostic (9.95e-2)" "unprognostic (8.66e-2)" "unprognostic (3.52e-2)" C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Group enriched" "Detected in some" 6 "Horizontal cells: 293.5;Oligodendrocyte precursor cells: 80.9;Thymic epithelial cells: 114.1" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 86.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Cholangiocyte, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Kidney - Mixed function" "Cluster 9: Neurons - Nervous system development" Vesicles Cytosol "HPA071349: " "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.7;Fibroblasts: 27.7;granulocytes: 9.9;Leydig cells: 21.3;Peritubular cells: 34.1;Smooth muscle cells: 12.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" C21orf58 ENSG00000160298 "Chromosome 21 open reading frame 58" P58505 21 46300181-46323875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.4;pituitary gland: 20.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 140.4;Erythroid cells: 70.8;Respiratory ciliated cells: 109.0;Spermatocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "HPA035110, HPA035111" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 56: Ciliated cells - Cilium assembly" Nucleoplasm "Nuclear bodies" "HPA035110: AB_10603683, HPA035111: AB_2674468" "unprognostic (2.19e-1)" "unprognostic (6.74e-3)" "unprognostic (2.51e-1)" "unprognostic (6.31e-3)" "unprognostic (1.08e-2)" "prognostic favorable (7.00e-4)" "unprognostic (4.74e-3)" "unprognostic (6.14e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (1.38e-1)" "prognostic favorable (4.20e-4)" "unprognostic (1.27e-1)" "unprognostic (1.01e-10)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (6.07e-2)" C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 5 "Fibroblasts: 708.6;Leydig cells: 1128.7;Theca cells: 421.0" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Neuroblastoma: 31.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" CABP7 MGC57793 ENSG00000100314 "Calcium binding protein 7" Q86V35 22 29720003-29731833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 38.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Inhibitory neurons: 1.0;Muller glia cells: 1.1;Oligodendrocyte precursor cells: 1.4;Rod photoreceptor cells: 1.1" "Group enriched" "Detected in some" 4 "glioma: 2.3;ovarian cancer: 1.0;pancreatic cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.5" "Pancreas - Beta cells, Thyroid - Parafollicular cells" "Group enriched" "Detected in all" 4 "cerebellum: 74.4;hippocampal formation: 204.8;midbrain: 60.3;pons and medulla: 110.0" "Region enhanced" "Detected in all" "hippocampal formation: 51.0" HPA016439 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 26: NCI-H716 - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA016439: AB_2669357" "unprognostic (1.88e-1)" "unprognostic (4.75e-2)" "unprognostic (1.18e-1)" "unprognostic (5.37e-2)" "unprognostic (4.55e-1)" "unprognostic (2.29e-4)" "unprognostic (2.05e-3)" "unprognostic (7.96e-2)" "unprognostic (8.69e-3)" "unprognostic (3.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (7.44e-7)" "unprognostic (1.25e-4)" "unprognostic (3.60e-2)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;pituitary gland: 6.8;testis: 5.1" "Group enriched" "Detected in some" 8 "Excitatory neurons: 383.1;Inhibitory neurons: 323.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in many" 8 "amygdala: 5.9;basal ganglia: 7.8;cerebral cortex: 10.2;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022919, HPA044347" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" Mitochondria "HPA022919: , HPA044347: AB_10960837" "unprognostic (1.34e-3)" "unprognostic (2.70e-2)" "unprognostic (8.08e-2)" "unprognostic (2.51e-7)" "unprognostic (8.10e-2)" "unprognostic (1.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (9.73e-4)" "unprognostic (5.98e-2)" "unprognostic (6.63e-6)" "unprognostic (4.25e-2)" "unprognostic (4.72e-1)" "unprognostic (7.77e-3)" "unprognostic (8.69e-2)" CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 39.9;Alveolar cells type 2: 121.1;Horizontal cells: 61.5;Inhibitory neurons: 35.2" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.3;thyroid cancer: 12.8" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 41: Alveolar cells - Lung function" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.6;Fibroblasts: 20.6;Rod photoreceptor cells: 44.2;Sertoli cells: 19.3;Theca cells: 56.2;Thymic epithelial cells: 25.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 38.4" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_2" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.9;Ductal cells: 32.1;Mucus glandular cells: 25.1;Sertoli cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 4.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.3" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 226.8;Enteroendocrine cells: 99.6;Intestinal goblet cells: 172.0;Paneth cells: 301.4;Proximal enterocytes: 491.7;Undifferentiated cells: 109.9" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 25.0;Gastric cancer: 11.6;liver cancer: 17.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 162.6;lymphoid tissue: 165.5;urinary bladder: 192.8" "Group enriched" "Detected in many" 9 "Basal respiratory cells: 29500.9;Ionocytes: 11560.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 67.0" "Pancreas - Ductal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 28000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: Liver cancer - Metabolism" "Cluster 5: Bronchus - Unknown function" "unprognostic (2.40e-1)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (7.06e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.53e-3)" "unprognostic (1.37e-1)" "unprognostic (5.21e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.19e-8)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.82e-1)" CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 401.6;Leydig cells: 405.9;Schwann cells: 200.4;Smooth muscle cells: 129.8" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cervical cancer: 41.2;Kidney cancer: 17.2;liver cancer: 45.7;Sarcoma: 37.5" "Adipose subcutaneous - Adipose progenitor cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2969.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 69: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 22 "NK-cells: 788.2;T-cells: 243.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 24 "Leukemia: 23.3;lymphoma: 24.2;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 68.6;Hofbauer cells: 91.5;Kupffer cells: 67.0;Langerhans cells: 50.7;Macrophages: 62.0;monocytes: 91.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cancer enriched" "Detected in many" 7 "Leukemia: 52.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 301.7;Endothelial cells: 261.2;Fibroblasts: 116.9;Leydig cells: 144.5;Peritubular cells: 120.1;Thymic epithelial cells: 170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Leukemia: 59.0;Rhabdoid: 112.2;Sarcoma: 91.0" "Breast - Fibroblasts, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 4 "NK-cells: 96.8;T-cells: 326.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Cancer enriched" "Detected in some" 7 "Leukemia: 19.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 333.8;dendritic cells: 239.0;Hofbauer cells: 395.4;Kupffer cells: 347.0;Langerhans cells: 203.1;Macrophages: 287.0;monocytes: 398.6;NK-cells: 431.6;T-cells: 288.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 71 "Leukemia: 172.3;lymphoma: 257.3;Myeloma: 140.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 14 "NK-cells: 1172.5;T-cells: 544.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Group enriched" "Detected in some" 7 "Leukemia: 49.8;liver cancer: 16.2;Myeloma: 24.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 153.9;Kupffer cells: 66.3;Langerhans cells: 193.7;Macrophages: 137.3;Microglial cells: 76.6;monocytes: 280.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Cell type enriched" "Detected in many" 4 "T-cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Group enriched" "Detected in some" 8 "Leukemia: 6.0;lymphoma: 10.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Cell type enriched" "Detected in many" 6 "T-cells: 154.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Group enriched" "Detected in some" 8 "Leukemia: 8.8;Myeloma: 33.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 6 "NK-cells: 121.7;T-cells: 195.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cancer enhanced" "Detected in many" "Leukemia: 31.4;skin cancer: 16.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Group enriched" "Detected in some" 146 "Distal enterocytes: 449.7;Enteroendocrine cells: 171.3;Intestinal goblet cells: 198.2;Paneth cells: 288.3;Proximal enterocytes: 316.8;Undifferentiated cells: 136.1" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Group enriched" "Detected in many" 5 "Bile duct cancer: 60.1;colorectal cancer: 155.8;Gastric cancer: 69.6;pancreatic cancer: 53.3" "Colon - Colon enterocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 296.8;Endothelial cells: 212.8;Extravillous trophoblasts: 50.9;Late spermatids: 86.2;Syncytiotrophoblasts: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 13.1;Rhabdoid: 12.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 139.7;Respiratory ciliated cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Group enriched" "Detected in some" 7 "Hofbauer cells: 9.5;Kupffer cells: 30.4;Macrophages: 22.3;monocytes: 16.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.8" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636463-48662886 "G-protein coupled receptors, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.3;pituitary gland: 7.3;retina: 3.8;testis: 2.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.3;Cone photoreceptor cells: 22.4;Excitatory neurons: 10.0;Horizontal cells: 21.1;Inhibitory neurons: 10.5;Rod photoreceptor cells: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "HPA062866: AB_2684886" "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (4.89e-1)" "unprognostic (9.12e-4)" "unprognostic (1.51e-1)" "unprognostic (1.59e-6)" "unprognostic (3.61e-6)" "unprognostic (1.86e-1)" "unprognostic (1.46e-3)" "unprognostic (5.07e-2)" "unprognostic (2.13e-3)" "unprognostic (2.87e-3)" "unprognostic (3.26e-3)" "unprognostic (9.53e-2)" "unprognostic (1.42e-1)" "unprognostic (3.86e-2)" "unprognostic (1.73e-1)" CEP126 KIAA1377 ENSG00000110318 "Centrosomal protein 126" Q9P2H0 11 101915010-102001062 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 144.1;Excitatory neurons: 123.2;Horizontal cells: 114.7;Respiratory ciliated cells: 142.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038381, HPA038399" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Cytosol" "HPA038381: AB_10669780, HPA038399: AB_10670157" "unprognostic (7.61e-2)" "unprognostic (6.75e-2)" "unprognostic (9.07e-2)" "unprognostic (1.02e-2)" "unprognostic (9.31e-2)" "unprognostic (8.87e-2)" "unprognostic (1.55e-4)" "unprognostic (1.52e-2)" "unprognostic (5.77e-2)" "unprognostic (9.55e-2)" "unprognostic (7.72e-3)" "unprognostic (8.87e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.30e-2)" "unprognostic (3.41e-1)" "unprognostic (9.61e-2)" "unprognostic (6.99e-3)" CERS1 "LAG1, LASS1, UOG1" ENSG00000223802 "Ceramide synthase 1" P27544 19 18868545-18896727 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 298.6;choroid plexus: 92.2" "Cell type enriched" "Detected in some" 8 "Late spermatids: 120.8" "Group enriched" "Detected in many" 5 "glioma: 13.5;melanoma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Sertoli cells" HPA045724 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 6: Late spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA045724: AB_10969762" "unprognostic (8.25e-2)" "unprognostic (8.91e-2)" "unprognostic (2.12e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.47e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (4.02e-1)" "unprognostic (7.04e-3)" "unprognostic (3.52e-3)" "unprognostic (1.92e-1)" "unprognostic (4.59e-2)" "unprognostic (2.99e-2)" "unprognostic (3.15e-2)" "unprognostic (9.15e-2)" "unprognostic (3.49e-1)" CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 41.8;Early spermatids: 165.0;Excitatory neurons: 79.3;Horizontal cells: 110.9;Inhibitory neurons: 54.9;Late spermatids: 153.4" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 36: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" CHRNB2 ENSG00000160716 "Cholinergic receptor nicotinic beta 2 subunit" P17787 1 154567778-154580013 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.4;retina: 8.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.2;Cone photoreceptor cells: 17.2;Excitatory neurons: 5.7;Horizontal cells: 21.8;Inhibitory neurons: 7.6;Late spermatids: 11.4;Rod photoreceptor cells: 5.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 17.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "unprognostic (1.13e-1)" "unprognostic (6.33e-2)" "unprognostic (8.15e-3)" "unprognostic (3.32e-1)" "unprognostic (4.37e-3)" "unprognostic (2.25e-1)" "unprognostic (3.51e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.37e-1)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (4.36e-1)" "unprognostic (2.32e-1)" "unprognostic (1.45e-1)" "unprognostic (5.65e-2)" "unprognostic (1.84e-1)" CHST8 GALNAC-4-ST1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "brain: 30.3;pituitary gland: 63.9" "Cell type enhanced" "Detected in some" "Early spermatids: 10.2;Excitatory neurons: 11.6;Horizontal cells: 13.5;Late spermatids: 54.9;Oligodendrocyte precursor cells: 11.6;Pancreatic endocrine cells: 13.7" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.8" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 6: Late spermatids - Spermatogenesis" "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 268.6;Gastric mucus-secreting cells: 62.6;Paneth cells: 186.0;Proximal enterocytes: 101.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2383.2;Glandular and luminal cells: 2376.1;Ionocytes: 1671.8;Paneth cells: 2229.6;Proximal enterocytes: 1664.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 964.6" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1325.5;Intestinal goblet cells: 775.6;Paneth cells: 891.5;Proximal enterocytes: 1352.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" CLDN9 ENSG00000213937 "Claudin 9" O95484 16 3012923-3014505 "Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8;pituitary gland: 25.2" "Group enriched" "Detected in some" 4 "Cholangiocytes: 15.4;Ductal cells: 8.7;Endometrial ciliated cells: 10.5;Respiratory ciliated cells: 17.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA076613 Supported "Vesicles,Cell Junctions" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 56: Ciliated cells - Cilium assembly" "Cell Junctions" Vesicles "HPA076613: AB_2686808" "unprognostic (7.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.24e-6)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "unprognostic (8.97e-3)" "unprognostic (4.51e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.55e-2)" CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 40.0;Hofbauer cells: 53.7;Kupffer cells: 219.9;Macrophages: 111.5;monocytes: 111.2" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 9 "Kidney cancer: 34.2;ovarian cancer: 11.5" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Group enriched" "Detected in many" 8 "Hofbauer cells: 188.6;Kupffer cells: 344.7;Langerhans cells: 338.1;Macrophages: 242.9;monocytes: 527.0;Schwann cells: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 12 "Myeloma: 69.4" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 448.9;Early spermatids: 208.0;Endometrial ciliated cells: 100.8;Muller glia cells: 149.5;Prostatic glandular cells: 106.6;Spermatocytes: 400.1" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 34.7" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Alveolar cells type 1: 79.0;Alveolar cells type 2: 44.9;Endothelial cells: 53.3;Langerhans cells: 140.8;Macrophages: 37.8;Schwann cells: 73.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Cancer enhanced" "Detected in many" "Myeloma: 35.7" "Breast - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.2;Excitatory neurons: 26.1;Fibroblasts: 59.3;Inhibitory neurons: 31.3;Peritubular cells: 60.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.7;intestine: 4.2;pituitary gland: 10.1;retina: 5.9" "Cell type enriched" "Detected in some" 11 "Cone photoreceptor cells: 34.5" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 2.5" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 44: Photoreceptor cells - Visual perception" "CAB079025: , HPA049378: AB_2732551" "unprognostic (2.34e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-2)" "unprognostic (4.81e-2)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.17e-4)" "unprognostic (4.65e-2)" "unprognostic (1.86e-3)" "unprognostic (2.88e-1)" "unprognostic (3.85e-3)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.71e-2)" CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Muller glia cells: 78.5;Paneth cells: 37.5;Sertoli cells: 24.9" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "Neuroblastoma: 94.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" CNTN5 "hNB-2, NB-2" ENSG00000149972 "Contactin 5" O94779 11 99020949-100358885 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;placenta: 2.6;salivary gland: 2.0;thyroid gland: 2.0" "Group enriched" "Detected in some" 14 "Excitatory neurons: 956.6;Inhibitory neurons: 2241.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039492, HPA041223" Approved "Intracellular and membrane" NA NA 480000 "Cluster 65: Brain - Ion transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 32: Neurons - Synaptic function" "HPA039492: AB_10795108, HPA041223: AB_10794549" "unprognostic (2.09e-2)" "unprognostic (3.40e-1)" "unprognostic (8.99e-3)" "unprognostic (4.20e-2)" "unprognostic (6.51e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.02e-2)" "unprognostic (8.72e-2)" "unprognostic (5.48e-3)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" COBL KIAA0633 ENSG00000106078 "Cordon-bleu WH2 repeat protein" O75128 7 51016212-51316818 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 118.2;skeletal muscle: 131.6;tongue: 107.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 195.9;Oligodendrocyte precursor cells: 338.9;Oligodendrocytes: 518.1;Skeletal myocytes: 148.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Pancreas - Ductal cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019033, HPA019167" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Plasma membrane, Cell Junctions" "HPA019033: AB_2083648, HPA019167: AB_1847070" "unprognostic (8.09e-2)" "unprognostic (1.08e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-3)" "unprognostic (3.13e-1)" "unprognostic (5.33e-3)" "unprognostic (2.90e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.21e-12)" "unprognostic (7.64e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-1)" "unprognostic (5.41e-3)" CPED1 "C7orf58, FLJ21986" ENSG00000106034 "Cadherin like and PC-esterase domain containing 1" A4D0V7 7 120988697-121297442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 78.5" "Cell type enhanced" "Detected in many" "Microglial cells: 223.5;Peritubular cells: 84.4;Skeletal myocytes: 55.4;Theca cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 10.8;intermediate monocyte: 11.3;myeloid DC: 25.2;non-classical monocyte: 7.6;plasmacytoid DC: 15.0" "Group enriched" "Detected in many" 9 "dendritic cells: 25.2;monocytes: 11.3" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012058 Uncertain Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA012058: AB_1845761" "unprognostic (7.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (4.48e-4)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.52e-3)" "prognostic favorable (3.00e-4)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (8.69e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.28e-3)" "unprognostic (5.05e-2)" "unprognostic (3.78e-1)" "unprognostic (6.54e-4)" CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 224.7;Glandular and luminal cells: 230.3;granulocytes: 310.5;Macrophages: 272.9;Sertoli cells: 320.6;Syncytiotrophoblasts: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 154.0;Langerhans cells: 182.3;Oligodendrocyte precursor cells: 220.0;Oligodendrocytes: 693.7" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Pancreas - Ductal cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Group enriched" "Detected in many" 5 "Extravillous trophoblasts: 116.5;Hofbauer cells: 330.9;Kupffer cells: 139.9;Langerhans cells: 99.2;Macrophages: 223.6;Microglial cells: 131.3;monocytes: 181.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Cancer enhanced" "Detected in many" "Leukemia: 10.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 246.2;Extravillous trophoblasts: 131.8;Langerhans cells: 711.1;Schwann cells: 142.6;Syncytiotrophoblasts: 349.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 6: BEWO - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1115.3;Extravillous trophoblasts: 1202.6;Hofbauer cells: 1047.1;Macrophages: 542.6;Syncytiotrophoblasts: 1877.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Pancreas - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Enzymes" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.6;Basal squamous epithelial cells: 1379.7;Breast myoepithelial cells: 1749.0;Fibroblasts: 1472.7;Glandular and luminal cells: 1617.8;Proximal tubular cells: 3452.0;Suprabasal keratinocytes: 1279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 170.2;head and neck cancer: 230.8" "Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: DU4475 - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Late spermatids: 4113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.3;intermediate monocyte: 107.5;myeloid DC: 38.2;neutrophil: 103.2;non-classical monocyte: 141.6" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.2;monocytes: 141.6" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1100000 6800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 83: Testis - Spermatogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 6: Late spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA053253: AB_2682091, HPA066315: AB_2685657" "unprognostic (4.64e-3)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (4.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.78e-2)" "unprognostic (4.74e-2)" "unprognostic (2.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.60e-1)" CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 509.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1381.2;Basal respiratory cells: 3144.8;Glandular and luminal cells: 1317.6;Ionocytes: 2384.1;Langerhans cells: 2569.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" CXCL3 "CINC-2b, GRO3, GROg, MIP-2b, SCYB3" ENSG00000163734 "C-X-C motif chemokine ligand 3" P19876 4 74036589-74038807 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.8;cervix: 20.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2490.6;Ionocytes: 1661.0;Langerhans cells: 2830.2;Macrophages: 857.2;monocytes: 1130.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;stomach cancer: 18.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" NA NA 28700 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (2.12e-3)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.08e-3)" "unprognostic (6.97e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-4)" "unprognostic (2.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.81e-1)" "unprognostic (2.89e-6)" "unprognostic (2.61e-3)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (1.20e-1)" CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;intestine: 6.4;lymphoid tissue: 16.3" "Cell type enriched" "Detected in some" 8 "dendritic cells: 385.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 306.7" "Group enriched" "Detected in many" 5 "dendritic cells: 306.7;NK-cells: 198.9;T-cells: 124.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 1.6;Leukemia: 1.5;lymphoma: 5.9;Myeloma: 4.3" "Adipose subcutaneous - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 88.1;T-cells: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 445.8" "Lineage enriched" "Detected in many" 5 "T-cells: 445.8" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0" "Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "dendritic cells: 334.1;Hofbauer cells: 226.4;Kupffer cells: 358.4;Macrophages: 451.2;monocytes: 516.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Cancer enhanced" "Detected in some" "Leukemia: 17.9;lymphoma: 28.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.6;Leydig cells: 197.5;Peritubular cells: 219.1;Proximal enterocytes: 701.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 62.6;Hepatocytes: 110.7;Proximal enterocytes: 55.0;Squamous epithelial cells: 28.1;Suprabasal keratinocytes: 63.0" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 11.2;liver cancer: 4.2;ovarian cancer: 3.3" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 54.8;Proximal enterocytes: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Cell type enriched" "Detected in many" 6 "Suprabasal keratinocytes: 536.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 190.8;Endothelial cells: 162.0;Microglial cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cancer enhanced" "Detected in many" "Bone cancer: 14.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Bone cancer - Transcription" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.9;Collecting duct cells: 86.6;Distal tubular cells: 59.1;Ductal cells: 126.2;Endometrial ciliated cells: 169.0;Glandular and luminal cells: 99.0;Proximal tubular cells: 63.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 47.6;ovarian cancer: 38.9;Uterine cancer: 34.0" "Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 91.4" "Cell type enhanced" "Detected in many" "Early spermatids: 399.7;Late spermatids: 83.2;Spermatocytes: 230.8" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.8" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 56: Neurons - Neuronal signaling" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 32.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 925.7;Inhibitory neurons: 562.4;Oligodendrocyte precursor cells: 243.6" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Group enriched" "Detected in many" 7 "basal ganglia: 32.3;cerebral cortex: 14.4;hippocampal formation: 9.2;hypothalamus: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "lung cancer: 1.9;Neuroblastoma: 4.1;Rhabdoid: 4.6" "Pancreas - Beta cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 192.8" HPA020321 Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 1039.4;Proximal enterocytes: 848.8" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 73: Prostatic glandular cells - Transcription" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520988 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.9;choroid plexus: 28.3;fallopian tube: 33.9;pituitary gland: 9.5;testis: 33.5" "Cell type enhanced" "Detected in some" "Early spermatids: 37.9;Endometrial ciliated cells: 49.1;Late spermatids: 32.9;Respiratory ciliated cells: 110.2;Spermatocytes: 46.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.5" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 65: Breast cancer - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" "HPA021649: AB_1847913, HPA021843: AB_1847914" "unprognostic (9.61e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" "unprognostic (1.44e-3)" "unprognostic (3.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (4.38e-1)" "unprognostic (1.51e-1)" "unprognostic (8.16e-3)" "unprognostic (8.14e-2)" "unprognostic (2.74e-2)" "unprognostic (3.77e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Group enriched" "Detected in many" 6 "Hofbauer cells: 160.0;Kupffer cells: 107.3;Langerhans cells: 369.8;Macrophages: 131.2;monocytes: 161.6;NK-cells: 233.6;T-cells: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 53 "Leukemia: 34.8;lymphoma: 11.6;Myeloma: 11.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 6 "Fibroblasts: 253.9;Leydig cells: 165.5;Peritubular cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.8;skin cancer: 2.4;thyroid cancer: 5.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 19 "Extravillous trophoblasts: 590.0;Syncytiotrophoblasts: 298.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cancer enriched" "Detected in many" 5 "lymphoma: 77.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 57.3;Hepatocytes: 47.5;Leydig cells: 123.8;Peritubular cells: 72.2;Smooth muscle cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 242.8;Endothelial cells: 304.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 19.7;pancreatic cancer: 12.6" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 53.1;salivary gland: 68.3;vagina: 106.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 87.4;Distal enterocytes: 63.1;Paneth cells: 71.0;Proximal enterocytes: 93.1;Squamous epithelial cells: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Rhabdoid: 18.6;Uterine cancer: 25.8" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 30900 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 50: Enterocytes - Absorption" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" ENC1 "ENC-1, KLHL37, NRPB, PIG10, TP53I10" ENSG00000171617 "Ectodermal-neural cortex 1" O14682 5 74627406-74641424 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 197.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 268.3;Theca cells: 270.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 51 "amygdala: 61.3;basal ganglia: 114.2;cerebral cortex: 190.0;hippocampal formation: 197.3;white matter: 68.6" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 263.2" HPA078061 Uncertain "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA078061: " "prognostic unfavorable (3.88e-4)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-3)" "unprognostic (1.36e-1)" "unprognostic (9.74e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (4.98e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (9.69e-2)" "unprognostic (3.08e-1)" "unprognostic (2.88e-1)" "unprognostic (5.65e-2)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 385.2;Endothelial cells: 271.5;Sertoli cells: 63.6;Smooth muscle cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 15.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 1642.8;Syncytiotrophoblasts: 1548.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Supported "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 1: T-cells - Immune response" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 99.5;Hepatocytes: 172.8;Leydig cells: 221.9;Peritubular cells: 237.0" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "liver cancer: 18.0" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" FAM135B C8ORFK32 ENSG00000147724 "Family with sequence similarity 135 member B" Q49AJ0 8 138130023-138497261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.7;retina: 9.1;testis: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 62.3;Early spermatids: 161.9;Excitatory neurons: 226.2;Inhibitory neurons: 261.4;Late spermatids: 48.1" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023911, HPA023950, HPA024815" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "Nuclear membrane" Nucleoplasm "HPA023911: AB_1845791, HPA023950: AB_1845792, HPA024815: AB_10601376" "unprognostic (3.78e-1)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (6.64e-2)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.36e-3)" "unprognostic (4.54e-2)" "unprognostic (6.85e-4)" "unprognostic (9.92e-3)" "unprognostic (9.82e-3)" "unprognostic (4.47e-1)" "unprognostic (2.70e-2)" "unprognostic (3.51e-2)" "unprognostic (1.30e-1)" FAM171A2 MGC34829 ENSG00000161682 "Family with sequence similarity 171 member A2" A8MVW0 17 44353215-44363853 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;pituitary gland: 7.9" "Group enriched" "Detected in some" 5 "Bipolar cells: 43.3;Horizontal cells: 31.4;Muller glia cells: 121.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.7" "Pancreas - Alpha cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019770 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 68: Muller glia cells - Visual perception" "HPA019770: AB_1848383" "unprognostic (1.28e-2)" "unprognostic (2.07e-2)" "unprognostic (4.14e-3)" "unprognostic (8.47e-2)" "unprognostic (9.98e-2)" "unprognostic (1.92e-1)" "unprognostic (1.62e-4)" "unprognostic (5.76e-2)" "unprognostic (1.98e-2)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (3.00e-1)" "unprognostic (2.43e-3)" "unprognostic (1.06e-1)" "unprognostic (1.38e-1)" "unprognostic (2.36e-2)" "unprognostic (4.76e-2)" FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Fibroblasts: 15.8;granulocytes: 4.9;Langerhans cells: 6.1;Melanocytes: 5.2;Pancreatic endocrine cells: 8.6;Peritubular cells: 4.1;Thymic epithelial cells: 5.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.6;Sarcoma: 23.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 264.8;intestine: 488.7;salivary gland: 468.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 362.6;Distal enterocytes: 895.2;Enteroendocrine cells: 314.4;Intestinal goblet cells: 1080.9;Ionocytes: 345.5;Paneth cells: 577.0;Proximal enterocytes: 354.1;Serous glandular cells: 524.0;Undifferentiated cells: 471.2" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 27.4;Gastric cancer: 12.9" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.8;Enteroendocrine cells: 54.8;Gastric mucus-secreting cells: 127.6;Intestinal goblet cells: 162.1;Paneth cells: 66.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.7;Gastric cancer: 11.6" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 88.4;Endometrial stromal cells: 85.2;Fibroblasts: 411.5;Leydig cells: 178.2;Peritubular cells: 218.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Fibroblasts: 214.7;Leydig cells: 626.8;Peritubular cells: 787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cancer enhanced" "Detected in many" "cervical cancer: 21.2" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Cell type enhanced" "Detected in many" "dendritic cells: 936.3;granulocytes: 1019.7;Hofbauer cells: 2872.0;Kupffer cells: 1487.5;Langerhans cells: 1904.8;Macrophages: 1775.7;monocytes: 2846.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 54.2;lymphoma: 18.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 23 "Intestinal goblet cells: 9989.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 10.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Group enriched" "Detected in many" 4 "Hofbauer cells: 203.5;Kupffer cells: 184.5;Langerhans cells: 426.8;Macrophages: 271.2;monocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 31.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Group enriched" "Detected in many" 6 "Hofbauer cells: 243.9;Kupffer cells: 232.2;Macrophages: 324.9;monocytes: 901.8;NK-cells: 607.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 66.4;dendritic cells: 58.3;Kupffer cells: 85.5;Langerhans cells: 53.1;Macrophages: 56.6;Microglial cells: 42.0;monocytes: 117.4;Schwann cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Group enriched" "Detected in some" 6 "Leukemia: 2.8;lymphoma: 9.5;Myeloma: 3.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Endothelial cells: 50.0;Microglial cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 6.5;testis cancer: 6.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Testis - Spermatogonia, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 31.4;Fibroblasts: 83.6;Granulosa cells: 43.6;Leydig cells: 42.0;Oligodendrocyte precursor cells: 30.8;Peritubular cells: 41.0;Schwann cells: 45.8" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "Rhabdoid: 100.0" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 200.4;Early spermatids: 339.9;Late spermatids: 227.0;Sertoli cells: 232.2;Smooth muscle cells: 334.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 37.6" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 62.6;Endothelial cells: 81.0;Kupffer cells: 94.4;Macrophages: 57.9;Microglial cells: 225.3;monocytes: 83.6;NK-cells: 75.3;T-cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.1;Myeloma: 20.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" FMO2 ENSG00000094963 "Flavin containing dimethylaniline monoxygenase 2" Q99518 1 171185249-171212686 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.7;lung: 93.9" "Cell type enhanced" "Detected in many" "Adipocytes: 190.6;Alveolar cells type 1: 116.9;Breast myoepithelial cells: 85.4;Club cells: 75.5;Endothelial cells: 90.3;Fibroblasts: 114.6;Mucus glandular cells: 81.6;Salivary duct cells: 110.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Fibroblast_1, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028261 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 266.4;prostate: 76.0" "Group enriched" "Detected in many" 16 "Oligodendrocytes: 347.0;Prostatic glandular cells: 556.8" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "prostate cancer: 223.1;Rhabdoid: 170.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Prostate glandular cells, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 73: Prostatic glandular cells - Transcription" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 997.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cancer enhanced" "Detected in single" "lymphoma: 3.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 64.2;Kupffer cells: 29.6;Langerhans cells: 301.0;Macrophages: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Cancer enriched" "Detected in some" 5 "Gastric cancer: 6.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" FRRS1L "C9orf4, CG-6" ENSG00000260230 "Ferric chelate reductase 1 like" Q9P0K9 9 109130293-109167249 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6;ovary: 11.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.7;Early spermatids: 32.7;Excitatory neurons: 90.3;Horizontal cells: 125.6;Inhibitory neurons: 79.4" "Cancer enhanced" "Detected in some" "glioma: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071086 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 9: Neurons - Nervous system development" "HPA071086: AB_2686342" "unprognostic (7.44e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (2.21e-1)" "unprognostic (9.01e-2)" "unprognostic (3.10e-1)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (9.94e-2)" "unprognostic (1.51e-1)" "unprognostic (9.21e-4)" "unprognostic (7.35e-3)" "unprognostic (7.02e-2)" "unprognostic (5.78e-3)" "unprognostic (5.89e-2)" "unprognostic (2.85e-1)" "unprognostic (5.38e-3)" FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 253.3;Early spermatids: 85.0;Excitatory neurons: 77.8;Late spermatids: 85.9;Rod photoreceptor cells: 135.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: AB_10601324" "unprognostic (9.28e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (3.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.17e-5)" "unprognostic (4.20e-2)" "unprognostic (5.65e-2)" "unprognostic (9.64e-3)" "unprognostic (2.66e-3)" "unprognostic (3.32e-2)" "unprognostic (8.28e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.07e-2)" "unprognostic (1.22e-3)" FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Extravillous trophoblasts: 4345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 183.9;Distal enterocytes: 177.7;Paneth cells: 183.8;Proximal enterocytes: 224.0;Syncytiotrophoblasts: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543840-94549898 "Metabolic proteins, Predicted membrane proteins" "Inflammatory response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 100.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 20.4;Gastric mucus-secreting cells: 21.5;Intestinal goblet cells: 24.7" "Cancer enhanced" "Detected in all" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 22.8;Leukemia: 24.6" "Pancreas - Ductal cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 26: Intestinal epithelial cells - Absorption" Vesicles "CAB000014: , CAB016129: AB_626918" "unprognostic (6.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.70e-3)" "unprognostic (2.46e-3)" "unprognostic (1.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (3.64e-4)" "unprognostic (7.26e-2)" "unprognostic (4.14e-1)" "unprognostic (4.81e-3)" "unprognostic (1.27e-1)" "unprognostic (9.08e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (3.10e-3)" FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.5;fallopian tube: 13.7;liver: 17.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.3;Collecting duct cells: 27.6;Early spermatids: 81.9;Hepatocytes: 27.1;Late spermatids: 98.7;Respiratory ciliated cells: 32.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in some" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (6.12e-5)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (9.19e-3)" "unprognostic (4.77e-3)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (3.71e-1)" "unprognostic (2.86e-4)" "unprognostic (3.84e-2)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-3)" GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Cell type enhanced" "Detected in some" "Early spermatids: 34.0;Intestinal goblet cells: 33.4;Late spermatids: 100.8;Oligodendrocyte precursor cells: 14.4" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Breast - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 51: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 16.6;Syncytiotrophoblasts: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: Non-specific - RNA binding" "Cluster 61: Non-specific - Transcription" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Group enriched" "Detected in many" 4 "monocytes: 38.2;NK-cells: 74.0;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 11.7;lymphoma: 11.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" GDAP1L1 ENSG00000124194 "Ganglioside induced differentiation associated protein 1 like 1" Q96MZ0 20 44247099-44280947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 30.7;pituitary gland: 17.7" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Excitatory neurons: 20.6;Horizontal cells: 17.9;Inhibitory neurons: 22.9;Late spermatids: 31.4;Oligodendrocyte precursor cells: 9.6" "Cancer enriched" "Detected in single" 14 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 14 "Neuroblastoma: 119.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054182, HPA063265" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Endoplasmic reticulum" "HPA054182: , HPA063265: AB_2684972" "unprognostic (6.58e-3)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-4)" "unprognostic (3.69e-1)" "unprognostic (5.15e-1)" "unprognostic (6.45e-2)" "unprognostic (7.69e-2)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (4.74e-3)" "unprognostic (2.41e-1)" "unprognostic (3.81e-5)" "unprognostic (8.57e-2)" "unprognostic (1.87e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-1)" GLB1L3 FLJ90231 ENSG00000166105 "Galactosidase beta 1 like 3" Q8NCI6 11 134274245-134319564 "Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;prostate: 7.9;seminal vesicle: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 12.4;Excitatory neurons: 38.9;Inhibitory neurons: 20.5;Oligodendrocyte precursor cells: 11.1;Spermatogonia: 8.2" "Cancer enhanced" "Detected in some" "prostate cancer: 5.0" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 11 "gdT-cell: 1.2;memory CD4 T-cell: 3.1;memory CD8 T-cell: 1.9;naive CD4 T-cell: 2.4;naive CD8 T-cell: 1.9;T-reg: 1.5" "Lineage enriched" "Detected in single" 31 "T-cells: 3.1" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.9" "Kidney - Proximal tubular cells, Pancreas - Alpha cells" "Not detected" "Not detected" HPA039916 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA039916: AB_2676746" "unprognostic (1.64e-3)" "unprognostic (7.80e-3)" "unprognostic (5.12e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (8.69e-3)" "prognostic favorable (1.97e-4)" "unprognostic (6.58e-3)" "unprognostic (3.81e-1)" "unprognostic (6.95e-3)" "unprognostic (9.73e-2)" "unprognostic (1.52e-5)" "unprognostic (1.39e-1)" "unprognostic (6.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 292.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 23.8" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 27.0" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "cervical cancer: 36.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 10.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.4;Early spermatids: 17.7;Excitatory neurons: 51.8;Horizontal cells: 13.5;Inhibitory neurons: 10.9;Late spermatids: 26.5" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.6" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078885 Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "HPA078885: " "unprognostic (2.75e-3)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (9.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.64e-5)" "unprognostic (4.61e-4)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 30.9;Early spermatids: 43.4;Fibroblasts: 49.8;Leydig cells: 56.8;Peritubular cells: 52.8;Thymic epithelial cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238587-16295549 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 358.6;tongue: 205.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 123.6;Erythroid cells: 93.7;Melanocytes: 118.4;Peritubular cells: 84.0;Prostatic glandular cells: 113.8;Sertoli cells: 110.6;Skeletal myocytes: 120.7" "Cancer enhanced" "Detected in all" "melanoma: 95.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Group enriched" "Detected in all" 6 "granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6" "Cancer enhanced" "Detected in many" "Leukemia: 37.6;skin cancer: 52.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Pancreas - Macrophages, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain NA NA 950000 "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 4: Platelets - Platelet activation" "HPA000904: AB_1078998, HPA021476: AB_1849858" "unprognostic (2.74e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (4.97e-3)" "unprognostic (3.52e-2)" "unprognostic (1.05e-1)" "unprognostic (3.06e-1)" "prognostic favorable (8.07e-4)" "unprognostic (4.12e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.15e-1)" "unprognostic (2.86e-1)" "prognostic favorable (2.94e-5)" "unprognostic (3.01e-1)" "unprognostic (1.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.17e-1)" GNAO1 G-ALPHA-o ENSG00000087258 "G protein subunit alpha o1" P09471 16 56191390-56357444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 171.2;retina: 52.4" "Cell type enhanced" "Detected in many" "Astrocytes: 131.6;Bipolar cells: 182.7;Excitatory neurons: 136.7;Horizontal cells: 86.5;Inhibitory neurons: 129.0;Oligodendrocyte precursor cells: 84.2;Oligodendrocytes: 347.7" "Cancer enriched" "Detected in many" 5 "glioma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 42.1" "Adipose subcutaneous - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008387, HPA040878" Enhanced NA NA 510000 "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "CAB008387: AB_591430, HPA040878: AB_2677184" "unprognostic (1.50e-1)" "unprognostic (1.36e-3)" "unprognostic (8.12e-2)" "unprognostic (1.63e-1)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (6.87e-2)" "unprognostic (1.68e-4)" "unprognostic (3.08e-1)" "unprognostic (1.74e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (6.86e-3)" "unprognostic (6.28e-2)" "unprognostic (1.21e-1)" "unprognostic (6.00e-1)" "unprognostic (9.70e-5)" GNG4 ENSG00000168243 "G protein subunit gamma 4" P50150 1 235547685-235650754 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.9;ovary: 32.1;pituitary gland: 32.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.6;Enteroendocrine cells: 31.8;Inhibitory neurons: 42.1;Oligodendrocyte precursor cells: 24.1;Pancreatic endocrine cells: 25.8;Prostatic glandular cells: 106.6;Proximal enterocytes: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cancer enhanced" "Detected in all" "Neuroblastoma: 118.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 6 "olfactory bulb: 469.3" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 73: Prostatic glandular cells - Transcription" "unprognostic (1.50e-3)" "unprognostic (8.33e-3)" "unprognostic (7.14e-2)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (4.94e-2)" "unprognostic (2.22e-2)" "unprognostic (3.10e-2)" "unprognostic (3.47e-2)" "unprognostic (3.49e-1)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (2.56e-9)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (1.68e-3)" "unprognostic (5.01e-3)" GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.2;Excitatory neurons: 329.3;Inhibitory neurons: 484.6;Oligodendrocyte precursor cells: 662.3;Rod photoreceptor cells: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 37.9;testis cancer: 39.5" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013601, HPA017671" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles" "HPA013601: , HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367407-74372622 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "Enteroendocrine cells: 1.2" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 55: Endocrine cells - Hormone signaling" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Pancreas - Beta cells" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Cluster 41: Non-specific - Cilium assembly" "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25174802-25602229 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 361.8;Inhibitory neurons: 294.5;Oligodendrocyte precursor cells: 401.9;Oligodendrocytes: 96.0" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 8.2" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 32: Neurons - Synaptic function" "HPA013185: AB_2113957" "unprognostic (4.43e-2)" "unprognostic (3.14e-2)" "unprognostic (7.42e-2)" "unprognostic (2.66e-5)" "unprognostic (5.67e-2)" "unprognostic (9.37e-2)" "unprognostic (4.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.60e-6)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (3.90e-1)" GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "B-cells: 34.3;NK-cells: 37.3;T-cells: 75.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 10.7;lymphoma: 3.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 109.5;retina: 39.0" "Group enriched" "Detected in many" 7 "Muller glia cells: 605.4;Oligodendrocytes: 306.7" "Group enriched" "Detected in many" 4 "glioma: 19.2;liver cancer: 5.7;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Approved "Nuclear membrane,Cytosol" No No 900000 "Cluster 70: Brain - Nervous system development" "Cluster 46: Non-specific - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "Nuclear membrane, Cytosol" "HPA042903: AB_2678219, HPA068009: AB_2685940" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.00e-5)" "unprognostic (6.19e-2)" "prognostic favorable (7.26e-4)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-2)" "unprognostic (6.12e-3)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-4)" GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.6;Horizontal cells: 15.4;Kupffer cells: 21.1;Macrophages: 16.2;Rod photoreceptor cells: 16.5;T-cells: 13.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Not detected" "Not detected" "Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 94.8;Late spermatids: 283.3;Oligodendrocytes: 161.4;Sertoli cells: 91.2" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 61.3;Distal enterocytes: 16.4;Intestinal goblet cells: 46.4;Late spermatids: 20.6;Proximal enterocytes: 20.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 5.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 26: Intestinal epithelial cells - Absorption" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Group enriched" "Detected in many" 7 "Erythroid cells: 28.7;granulocytes: 107.3;NK-cells: 43.6;T-cells: 56.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Cancer enriched" "Detected in some" 6 "Leukemia: 27.7" "Adipose visceral - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 4: Platelets - Platelet activation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" GRM4 "GPRC1D, mGlu4, MGLUR4" ENSG00000124493 "Glutamate metabotropic receptor 4" Q14833 6 34018643-34155622 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "brain: 80.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Horizontal cells: 19.9;Inhibitory neurons: 10.6;Late spermatids: 3.6;Spermatogonia: 4.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Region enriched" "Detected in all" 7 "cerebellum: 80.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in all" "cerebellum: 79.1" "Region enriched" "Detected in many" 5 "cerebellum: 138.8" CAB022096 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 37: Neurons - Neuronal signaling" "CAB022096: " "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (7.00e-2)" "unprognostic (4.03e-2)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (3.56e-1)" "unprognostic (9.45e-2)" "unprognostic (2.08e-2)" "unprognostic (6.21e-3)" "unprognostic (2.44e-1)" "unprognostic (2.15e-11)" "unprognostic (5.32e-2)" "unprognostic (9.16e-2)" "unprognostic (6.57e-2)" "unprognostic (3.07e-1)" GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Hofbauer cells: 4.5;Macrophages: 5.0;Serous glandular cells: 2.4;Suprabasal keratinocytes: 2.5;Theca cells: 1.7;Thymic epithelial cells: 3.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "breast cancer: 3.7;colorectal cancer: 4.1" "Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 2: DU4475 - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 41 "NK-cells: 678.2;T-cells: 222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" HAP1 "HAP2, hHLP1, HIP5, HLP" ENSG00000173805 "Huntingtin associated protein 1" P54257 17 41717742-41734644 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 68.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 66.4;Oligodendrocyte precursor cells: 14.0;Syncytiotrophoblasts: 18.1" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 39.9" "Pancreas - Alpha cells, Prostate - Prostate basal glandular cells, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023394, HPA076992" Enhanced Supported Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: Bone cancer - Transcription" "Cluster 14: Endometrium - Transcription regulation" Cytosol Nucleoli "HPA023394: AB_1850492, HPA076992: AB_2686822" "unprognostic (2.84e-3)" "unprognostic (3.74e-3)" "unprognostic (2.42e-2)" "unprognostic (2.30e-1)" "unprognostic (7.53e-2)" "unprognostic (4.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.32e-1)" "unprognostic (6.11e-2)" "unprognostic (8.76e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.38e-1)" "unprognostic (2.46e-2)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-2)" "unprognostic (9.29e-2)" HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 168.9;Hofbauer cells: 166.8;Kupffer cells: 419.9;Macrophages: 339.0;monocytes: 388.0;NK-cells: 186.3;T-cells: 179.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Leukemia: 183.8;lymphoma: 217.7;Myeloma: 213.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 146.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 55.5;Excitatory neurons: 12.6;Horizontal cells: 28.2;Inhibitory neurons: 18.3;Oligodendrocytes: 58.6" "Group enriched" "Detected in many" 6 "glioma: 8.7;melanoma: 5.7;renal cancer: 2.8;testis cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 2: DU4475 - Unknown function" "Cluster 35: Bipolar cells - Visual perception" "unprognostic (8.69e-2)" "unprognostic (3.97e-3)" "unprognostic (3.31e-4)" "unprognostic (1.44e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-3)" "unprognostic (8.00e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.53e-4)" "unprognostic (9.72e-3)" HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.4;Excitatory neurons: 79.4;Inhibitory neurons: 74.4;Oligodendrocytes: 22.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.7" "Liver - Hepatic stellate cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 62.8;Endothelial cells: 47.0;Late spermatids: 17.0;Microglial cells: 14.6;Peritubular cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Enzymes" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 897.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 530.6;Skeletal myocytes: 303.9;Syncytiotrophoblasts: 1686.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Cytosol Nucleoplasm "HPA015876: AB_1850458" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.47e-1)" "unprognostic (4.03e-2)" "unprognostic (7.91e-2)" "unprognostic (6.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.36e-2)" "unprognostic (2.17e-2)" HTR1D "5-HT1D, HT1DA, HTRL, RDC4" ENSG00000179546 "5-hydroxytryptamine receptor 1D" P28221 1 23191895-23194729 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.4;intestine: 9.4" "Group enriched" "Detected in some" 5 "Cholangiocytes: 5.8;Proximal enterocytes: 7.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Pancreas - Ductal cells, Testis - Late spermatids" NA NA "Cluster 45: Intestine - Brush border" "Cluster 41: Non-specific - Cilium assembly" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (1.73e-2)" "unprognostic (8.69e-3)" "unprognostic (8.86e-3)" "unprognostic (2.03e-1)" "unprognostic (2.65e-2)" "unprognostic (5.97e-4)" "prognostic unfavorable (1.86e-4)" "unprognostic (3.87e-3)" "unprognostic (8.88e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (5.30e-4)" "unprognostic (3.17e-2)" "unprognostic (3.28e-6)" "unprognostic (9.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.45e-1)" "unprognostic (8.02e-3)" IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1239.4;Leydig cells: 1826.4;Muller glia cells: 615.9;Peritubular cells: 1001.5;Sertoli cells: 616.4;Smooth muscle cells: 1293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 341.6;breast cancer: 389.0" "Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040514, HPA070407" Supported Approved Vesicles "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA040514: AB_2677016, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 538.2;Fibroblasts: 1434.1;Leydig cells: 997.0;Peritubular cells: 1559.1;Sertoli cells: 500.3;Smooth muscle cells: 554.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 31 "B-cells: 2040.6;Plasma cells: 6710.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Cancer enriched" "Detected in some" 10 "Myeloma: 1216.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 25 "B-cells: 1189.2;Plasma cells: 2469.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 29 "lymphoma: 76.6;Myeloma: 22.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 14 "Plasma cells: 4.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.6" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 127 "Plasma cells: 43.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Cell type enriched" "Detected in some" 259 "Plasma cells: 1191.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 45: Plasma cells - Humoral immune response" IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Cell type enriched" "Detected in single" 13 "Plasma cells: 1.3" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cancer enriched" "Detected in single" 140 "lymphoma: 14.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in some" 282 "Plasma cells: 6914.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 10 "Leukemia: 1.7;lymphoma: 3.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA006014: " IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in single" 187 "Plasma cells: 129.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 913 "Plasma cells: 4001.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cancer enriched" "Detected in single" 33 "Myeloma: 22.0" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 21 "Plasma cells: 1145.7" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;lymphoid tissue: 12.5;salivary gland: 5.7" "Cell type enriched" "Detected in some" 9 "Plasma cells: 18.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Cancer enhanced" "Detected in single" "Myeloma: 1.2" "Breast - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 1000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 573 "Plasma cells: 2945.6" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Group enriched" "Detected in some" 21 "lymphoma: 3.1;Myeloma: 1.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 65 "Plasma cells: 574.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Group enriched" "Detected in some" 13 "lymphoma: 1.2;Myeloma: 1.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 550 "Plasma cells: 2239.3" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cancer enriched" "Detected in single" 44 "lymphoma: 12.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 213 "Plasma cells: 921.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cancer enriched" "Detected in many" 1355 "Myeloma: 4518.2" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 5 "Plasma cells: 154.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Group enriched" "Detected in some" 11 "B-cells: 1.2;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 160 "Plasma cells: 921.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 91 "Plasma cells: 843.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 36 "Leukemia: 236.9;lymphoma: 904.2" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 7 "Plasma cells: 41.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Cancer enriched" "Detected in single" 131 "lymphoma: 50.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 188.3;Late spermatids: 42.1;Microglial cells: 60.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 13.6;Rhabdoid: 6.6" "Colon - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 167.2;Excitatory neurons: 81.0;Microglial cells: 73.0;Oligodendrocyte precursor cells: 135.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.1;thyroid cancer: 7.4" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 35: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 15.9;liver: 24.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.7;Enteroendocrine cells: 5.8;Hepatocytes: 14.7;Late spermatids: 11.9;Proximal enterocytes: 41.4" "Cancer enriched" "Detected in some" 10 "liver cancer: 12.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "cervical cancer: 6.7;Kidney cancer: 4.7" "Pancreas - Ductal cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm "Cell Junctions" "HPA051811: AB_2681621" "unprognostic (1.54e-1)" "unprognostic (1.84e-3)" "unprognostic (5.74e-2)" "unprognostic (1.53e-3)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.20e-6)" "unprognostic (7.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-3)" "unprognostic (1.52e-1)" "unprognostic (1.19e-8)" "unprognostic (1.26e-1)" "unprognostic (6.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.85e-1)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 112.9;dendritic cells: 93.7;Distal enterocytes: 87.2;Langerhans cells: 151.6;NK-cells: 284.8;Plasma cells: 91.0;Proximal enterocytes: 80.8;T-cells: 197.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 203.1;lymphoma: 129.5;Myeloma: 347.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA046641 Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Plasma membrane" "Endoplasmic reticulum" "HPA046641: AB_2679733" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164919-10243745 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 53.6;Oligodendrocytes: 32.4;Schwann cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" Vesicles "CAB013483: , HPA050520: AB_2681154" "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favorable (6.60e-5)" ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 233.4;Endothelial cells: 116.1;Hepatocytes: 86.4;Smooth muscle cells: 149.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 5 "Astrocytes: 84.8;Cardiomyocytes: 173.2;Sertoli cells: 55.3;Skeletal myocytes: 72.3;Smooth muscle cells: 93.4" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 28.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pancreas - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.6;monocytes: 151.0;NK-cells: 195.1;T-cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 125 "Leukemia: 74.5;lymphoma: 40.6;Myeloma: 51.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 760.4;Kupffer cells: 784.3;Langerhans cells: 320.5;Macrophages: 522.0;monocytes: 733.4;NK-cells: 698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 67.2;Leukemia: 198.4;lymphoma: 74.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.8;Alveolar cells type 2: 101.5;Basal respiratory cells: 120.6;Collecting duct cells: 72.9;Ductal cells: 64.0;Exocrine glandular cells: 185.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" JAKMIP1 "FLJ31564, Gababrbp, JAMIP1, MARLIN1" ENSG00000152969 "Janus kinase and microtubule interacting protein 1" Q96N16 4 6026199-6200591 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.1;pituitary gland: 10.2;retina: 17.0" "Group enriched" "Detected in some" 5 "Astrocytes: 34.5;Excitatory neurons: 81.7;Inhibitory neurons: 52.3;Muller glia cells: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "gdT-cell: 25.3;MAIT T-cell: 11.2;memory CD4 T-cell: 11.2;memory CD8 T-cell: 22.6;naive CD8 T-cell: 10.1;T-reg: 36.7" "Lineage enriched" "Detected in many" 33 "T-cells: 36.7" "Cancer enhanced" "Detected in some" "lymphoma: 12.6;Myeloma: 9.6;Neuroblastoma: 8.2" "Adipose subcutaneous - T-cells, Colon - Colon enteroendocrine cells, Liver - T-cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044570 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA044570: AB_2678995" "unprognostic (4.79e-2)" "unprognostic (3.46e-3)" "unprognostic (4.90e-2)" "unprognostic (1.73e-2)" "unprognostic (5.34e-2)" "unprognostic (3.86e-3)" "unprognostic (6.16e-2)" "unprognostic (6.69e-3)" "unprognostic (4.25e-4)" "unprognostic (7.14e-2)" "unprognostic (4.57e-3)" "unprognostic (1.13e-1)" "unprognostic (3.70e-8)" "unprognostic (1.85e-2)" "unprognostic (3.15e-1)" "unprognostic (4.23e-2)" "unprognostic (2.96e-3)" JSRP1 "FLJ32416, JP-45" ENSG00000167476 "Junctional sarcoplasmic reticulum protein 1" Q96MG2 19 2252252-2269759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skeletal muscle: 335.4" "Group enriched" "Detected in some" 7 "Plasma cells: 139.9;Skeletal myocytes: 206.9" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "naive B-cell: 2.6" "Lineage enriched" "Detected in single" 10 "B-cells: 2.6" "Cancer enriched" "Detected in many" 6 "Myeloma: 168.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Pancreas - Alpha cells, Stomach - Plasma cells, Testis - Late spermatids" "Group enriched" "Detected in many" 6 "amygdala: 8.4;basal ganglia: 11.6;cerebral cortex: 9.9;hippocampal formation: 4.4;white matter: 5.1" "Not detected" "Not detected" HPA044741 Enhanced Approved "Endoplasmic reticulum" NA NA 13000 "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA044741: AB_10794295" "unprognostic (9.41e-3)" "unprognostic (1.52e-2)" "unprognostic (1.39e-1)" "unprognostic (5.85e-2)" "unprognostic (2.15e-1)" "unprognostic (9.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.80e-2)" "unprognostic (2.44e-2)" "unprognostic (1.87e-2)" "unprognostic (8.64e-5)" "unprognostic (3.63e-1)" "unprognostic (4.43e-1)" "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" KCNA5 "HK2, HPCN1, Kv1.5" ENSG00000130037 "Potassium voltage-gated channel subfamily A member 5" P22460 12 5043879-5046788 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 52.7;heart muscle: 39.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 130.0;Cardiomyocytes: 21.7;dendritic cells: 19.1;Horizontal cells: 34.6;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 122 "plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 122 "dendritic cells: 12.2" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "HPA021516, CAB022562" Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 35: Bipolar cells - Visual perception" "CAB022562: , HPA021516: AB_2670732" "unprognostic (3.87e-1)" "unprognostic (9.91e-3)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (7.06e-3)" "unprognostic (1.20e-1)" "unprognostic (4.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.14e-1)" "unprognostic (2.37e-2)" "unprognostic (5.08e-3)" "unprognostic (6.73e-4)" "unprognostic (1.92e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (3.08e-2)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 180.9;Excitatory neurons: 275.0;Inhibitory neurons: 235.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Group enriched" "Detected in some" 8 "Astrocytes: 56.0;Inhibitory neurons: 215.5;Microglial cells: 163.3;Oligodendrocyte precursor cells: 187.7" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 22.9" "Pancreas - Alpha cells, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 32: Neurons - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 45.9;Enteroendocrine cells: 17.2;Plasma cells: 12.2;Respiratory ciliated cells: 68.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Group enriched" "Detected in some" 10 "Gastric cancer: 1.5;lung cancer: 4.0;prostate cancer: 5.0" "Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 56: Ciliated cells - Cilium assembly" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "brain: 1628.2;choroid plexus: 951.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.6;Endometrial stromal cells: 12.6;Excitatory neurons: 28.0;Horizontal cells: 47.4;Inhibitory neurons: 21.2;Late spermatids: 23.8" "Cancer enriched" "Detected in some" 5 "glioma: 26.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Cytosol" "Mitotic spindle" "HPA004469: AB_1079212, HPA073448: AB_2686601" "unprognostic (7.94e-2)" "unprognostic (4.95e-3)" "unprognostic (3.87e-1)" "unprognostic (3.34e-3)" "unprognostic (7.12e-2)" "unprognostic (4.22e-2)" "unprognostic (3.22e-5)" "unprognostic (2.82e-1)" "unprognostic (2.01e-1)" "unprognostic (1.52e-2)" "prognostic favorable (5.23e-4)" "unprognostic (7.61e-2)" "unprognostic (2.26e-4)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (4.12e-1)" "unprognostic (1.51e-1)" KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 263.4;Early spermatids: 309.6;Excitatory neurons: 263.4;Horizontal cells: 375.6;Inhibitory neurons: 243.3;Late spermatids: 817.0;Oligodendrocytes: 255.6;Prostatic glandular cells: 191.1" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 34.6" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 7 "NK-cells: 1508.8;T-cells: 767.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 5 "NK-cells: 229.4;T-cells: 105.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Group enriched" "Detected in some" 7 "NK-cells: 25.4;T-cells: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Group enriched" "Detected in some" 5 "NK-cells: 26.5;T-cells: 41.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Group enriched" "Detected in some" 11 "Leukemia: 10.3;lymphoma: 33.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 150.5" "Group enriched" "Detected in some" 5 "Early spermatids: 43.9;Late spermatids: 22.1;NK-cells: 39.5;T-cells: 15.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 9 "basophil: 87.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.5" "Cancer enhanced" "Detected in many" "breast cancer: 54.2" "Pancreas - Ductal cells, Skin - Hair cortex cells, Testis - Early spermatids, Testis - Late spermatids" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 65: Breast cancer - Unknown function" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 122.2;Basal respiratory cells: 205.5;Basal squamous epithelial cells: 153.4;Ductal cells: 176.1;Exocrine glandular cells: 221.8;Pancreatic endocrine cells: 163.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 476.8" "Breast - Breast myoepithelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, HPA046540, CAB078165" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: , HPA046540: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Cell type enhanced" "Detected in many" "B-cells: 876.2;dendritic cells: 488.5;granulocytes: 661.3;Hofbauer cells: 1304.4;Kupffer cells: 804.8;Langerhans cells: 566.9;Macrophages: 910.5;monocytes: 1416.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 486.0;lymphoma: 401.3;Myeloma: 125.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 44.9;Excitatory neurons: 17.5;Horizontal cells: 17.9;Inhibitory neurons: 23.2;Melanocytes: 78.4;Oligodendrocytes: 55.2" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 31 "skin cancer: 14.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Uncertain Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 41: Alveolar cells - Lung function" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" LHFPL4 GARLH4 ENSG00000156959 "LHFPL tetraspan subfamily member 4" Q7Z7J7 3 9498361-9553822 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 15.5;pituitary gland: 12.2;retina: 9.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.0;Excitatory neurons: 59.1;Horizontal cells: 22.4;Inhibitory neurons: 65.6;Oligodendrocyte precursor cells: 32.7;Rod photoreceptor cells: 16.2" "Group enriched" "Detected in some" 4 "glioma: 6.8;testis cancer: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 12.5;Neuroblastoma: 12.5" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041421 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoplasm "HPA041421: AB_10796673" "unprognostic (6.81e-2)" "unprognostic (3.65e-2)" "unprognostic (4.50e-1)" "unprognostic (6.62e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (2.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.65e-2)" "unprognostic (6.59e-2)" "unprognostic (1.12e-2)" "unprognostic (3.77e-1)" "unprognostic (1.90e-2)" "unprognostic (6.78e-2)" "unprognostic (2.99e-1)" "unprognostic (3.03e-3)" "unprognostic (8.21e-2)" LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 181.3;Astrocytes: 210.0;Excitatory neurons: 196.3;Extravillous trophoblasts: 188.4;Fibroblasts: 246.5;Leydig cells: 303.1;Microglial cells: 420.5;Oligodendrocyte precursor cells: 271.0;Smooth muscle cells: 276.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Uncertain Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 98.6;Endometrial ciliated cells: 69.3;Glandular and luminal cells: 180.4;granulocytes: 116.9;Ionocytes: 283.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 14: Endometrium - Transcription regulation" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 8 "Hofbauer cells: 52.7;Kupffer cells: 69.8;Macrophages: 41.6;monocytes: 102.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 188.5;Hofbauer cells: 139.3;Kupffer cells: 84.7;Macrophages: 91.4;monocytes: 45.8;Plasma cells: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cancer enriched" "Detected in some" 5 "Myeloma: 25.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" LINGO2 "LERN3, LRRN6C" ENSG00000174482 "Leucine rich repeat and Ig domain containing 2" Q7L985 9 27948078-28670286 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.5;smooth muscle: 8.8" "Group enriched" "Detected in some" 30 "Excitatory neurons: 1566.5;Inhibitory neurons: 960.6" "Cancer enhanced" "Detected in single" "melanoma: 0.8" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 9 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 9 "NK-cells: 1.0" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 10.4" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA016633, CAB025361" Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "CAB025361: , HPA016633: AB_1853362" "unprognostic (1.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-4)" "unprognostic (9.86e-4)" "unprognostic (7.55e-3)" "unprognostic (2.67e-6)" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.08e-2)" "unprognostic (2.30e-2)" "unprognostic (1.95e-4)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.7;stomach 1: 48.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.3;Gastric mucus-secreting cells: 174.1;Intestinal goblet cells: 156.8;Ionocytes: 403.8;Proximal enterocytes: 140.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 38.6;pancreatic cancer: 33.6" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA049079 Approved "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" LMNTD1 "FLJ36004, IFLTD1, Pas1c1" ENSG00000152936 "Lamin tail domain containing 1" Q8N9Z9 12 25409307-25648579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 14.7;fallopian tube: 17.0;testis: 14.8" "Group enriched" "Detected in some" 4 "Astrocytes: 14.6;Early spermatids: 43.7;Endometrial ciliated cells: 20.3;Late spermatids: 40.2" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038640 Approved Nucleoplasm,Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Centrosome" "HPA038640: AB_2676127" "unprognostic (8.92e-3)" "unprognostic (3.21e-1)" "unprognostic (2.41e-1)" "unprognostic (1.19e-2)" "unprognostic (9.57e-2)" "unprognostic (1.68e-1)" "unprognostic (6.18e-2)" "unprognostic (2.42e-1)" "unprognostic (7.80e-2)" "unprognostic (3.89e-2)" LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;skeletal muscle: 29.3;tongue: 12.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 28.0;Early spermatids: 63.3;Horizontal cells: 14.7;Pancreatic endocrine cells: 53.2" "Cancer enriched" "Detected in many" 6 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.2;Neuroblastoma: 20.1" "Pancreas - Alpha cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 47: Retina - Visual perception" "Cluster 49: Early spermatids - Spermatogenesis" "unprognostic (3.74e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-6)" "unprognostic (9.34e-2)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.06e-3)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (9.05e-2)" "unprognostic (4.36e-12)" "unprognostic (1.76e-2)" "unprognostic (8.88e-2)" "unprognostic (2.58e-2)" "unprognostic (3.13e-2)" LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 108.4;Endothelial cells: 156.7;Erythroid cells: 86.4;monocytes: 120.3" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cancer enriched" "Detected in many" 4 "Leukemia: 47.0" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 13 "Excitatory neurons: 862.2;Inhibitory neurons: 568.8;Oligodendrocyte precursor cells: 283.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.1" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRRC10B ENSG00000204950 "Leucine rich repeat containing 10B" A6NIK2 11 61508749-61511018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 42.4;fallopian tube: 28.7;pituitary gland: 33.7" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 55.4;Respiratory ciliated cells: 89.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.8" "Region enhanced" "Detected in many" "basal ganglia: 42.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.3;Sarcoma: 3.6" "Heart muscle - Smooth muscle cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "basal ganglia: 222.5" "Group enriched" "Detected in many" 5 "basal ganglia: 30.9;hippocampal formation: 24.2" HPA047619 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 10: Brain - Neuronal signaling" "Cluster 2: DU4475 - Unknown function" "Cluster 56: Ciliated cells - Cilium assembly" Nucleoplasm Nucleoli "HPA047619: AB_2680106" "unprognostic (9.95e-2)" "unprognostic (2.67e-2)" "unprognostic (4.92e-2)" "unprognostic (1.26e-2)" "unprognostic (2.11e-1)" "unprognostic (1.32e-1)" "unprognostic (6.10e-2)" "unprognostic (9.22e-2)" "unprognostic (4.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.21e-3)" "unprognostic (2.52e-2)" "unprognostic (5.27e-4)" "unprognostic (5.07e-2)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (6.63e-2)" LRRC19 FLJ21302 ENSG00000184434 "Leucine rich repeat containing 19" Q9H756 9 26993136-27005672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 36.2;kidney: 42.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.6;Distal enterocytes: 112.9;Enteroendocrine cells: 20.3;Intestinal goblet cells: 24.7;Paneth cells: 29.7;Proximal enterocytes: 70.2;Proximal tubular cells: 52.5" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.0;renal cancer: 5.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 190000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (6.30e-2)" "unprognostic (5.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.05e-2)" "unprognostic (1.85e-2)" "unprognostic (4.16e-2)" "unprognostic (9.21e-5)" "unprognostic (1.87e-2)" "unprognostic (4.48e-2)" "prognostic favorable (7.08e-8)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 7 "Hofbauer cells: 69.1;Kupffer cells: 95.6;Macrophages: 85.0;monocytes: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;lymphoma: 2.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.3;lung: 9.7" "Group enriched" "Detected in some" 10 "Alveolar cells type 1: 26.6;Thymic epithelial cells: 52.3" "Group enriched" "Detected in many" 7 "lung cancer: 4.6;ovarian cancer: 3.6;renal cancer: 11.7" "Region enhanced" "Detected in some" "basal ganglia: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 40.7;Uterine cancer: 23.6" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 73000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 41: Alveolar cells - Lung function" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: AB_2686770" "unprognostic (6.16e-2)" "unprognostic (1.69e-3)" "unprognostic (2.40e-3)" "unprognostic (9.04e-3)" "unprognostic (5.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (8.94e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-3)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "unprognostic (2.31e-1)" "unprognostic (9.84e-3)" LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 10.9;Fibroblasts: 51.3;Leydig cells: 27.5;Melanocytes: 26.1;Peritubular cells: 17.4" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.1" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;retina: 41.3" "Group enriched" "Detected in many" 14 "Astrocytes: 3275.7;Excitatory neurons: 986.3;Inhibitory neurons: 2090.3;Oligodendrocyte precursor cells: 2375.5;Oligodendrocytes: 881.6" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.4" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 63: Astrocytes - Nervous system maintenance" Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 105.0;Cardiomyocytes: 89.9;Fibroblasts: 92.5;Leydig cells: 95.6;Mucus glandular cells: 116.8;Peritubular cells: 162.3;Smooth muscle cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 10 "B-cells: 154.3;Hofbauer cells: 258.4;Kupffer cells: 157.5;Langerhans cells: 123.9;Macrophages: 146.7;Microglial cells: 103.1;monocytes: 146.5;Schwann cells: 66.4" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Group enriched" "Detected in some" 176 "Leukemia: 38.8;lymphoma: 38.4;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 245.9;dendritic cells: 62.8;Langerhans cells: 37.8;Plasma cells: 72.1;T-cells: 45.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 12.3;Myeloma: 38.9" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Pancreas - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.9;Exocrine glandular cells: 71.1;Ionocytes: 78.1;Mucus glandular cells: 145.9;Respiratory ciliated cells: 73.6;Salivary duct cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 43.5;dendritic cells: 52.8;Langerhans cells: 30.6;monocytes: 22.5;Plasma cells: 34.7;Rod photoreceptor cells: 65.2;T-cells: 39.5" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 39 "Leukemia: 16.9;lymphoma: 52.8;Myeloma: 29.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 353.3" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 29.9" "Kidney - Podocytes, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 27.2;Cardiomyocytes: 29.4;Cholangiocytes: 26.9;Endometrial stromal cells: 30.1;Fibroblasts: 17.1;Hepatocytes: 58.1" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.0;Rhabdoid: 14.0" "Breast - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 20.3;Cone photoreceptor cells: 32.7;Excitatory neurons: 63.8;Horizontal cells: 40.4;Inhibitory neurons: 68.7;Oligodendrocyte precursor cells: 21.2" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cancer enhanced" "Detected in all" "Neuroblastoma: 25.6" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 37: Neurons - Neuronal signaling" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" MCC ENSG00000171444 "MCC regulator of WNT signaling pathway" P23508 5 113022099-113488823 "Predicted intracellular proteins" "Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 70.6" "Cell type enhanced" "Detected in many" "Astrocytes: 165.4;Bipolar cells: 119.4;Inhibitory neurons: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Sarcoma: 45.1" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037390, HPA037391" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: TE 441.T - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA037390: AB_2675451, HPA037391: AB_10671248" "unprognostic (6.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (8.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-1)" "unprognostic (5.21e-2)" "unprognostic (9.59e-2)" "unprognostic (8.02e-3)" "unprognostic (1.56e-1)" "unprognostic (1.74e-1)" "prognostic favorable (6.19e-4)" "unprognostic (1.70e-3)" "unprognostic (3.34e-1)" "unprognostic (2.47e-2)" "unprognostic (2.90e-1)" MCF2L2 "ARHGEF22, KIAA0861" ENSG00000053524 "MCF.2 cell line derived transforming sequence-like 2" Q86YR7 3 183178043-183428778 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.5;retina: 28.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 73.6;Cone photoreceptor cells: 122.4;Excitatory neurons: 174.5;Inhibitory neurons: 146.4;Oligodendrocyte precursor cells: 177.6;Oligodendrocytes: 65.3;Rod photoreceptor cells: 149.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.6" "Lineage enriched" "Detected in single" 15 "T-cells: 1.6" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA038946, HPA038947, HPA061485" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "Centriolar satellite, Cytosol" "HPA038946: AB_10670914, HPA038947: AB_10672655, HPA061485: " "unprognostic (2.17e-2)" "unprognostic (4.42e-1)" "unprognostic (3.08e-1)" "unprognostic (1.95e-3)" "unprognostic (1.98e-1)" "unprognostic (2.87e-2)" "unprognostic (3.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (5.08e-2)" "unprognostic (4.80e-4)" "unprognostic (1.32e-1)" "unprognostic (8.75e-6)" "unprognostic (1.09e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" MECP2 "MRX16, MRX79, RTT" ENSG00000169057 "Methyl-CpG binding protein 2" P51608 X 154021573-154137103 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 47.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 47.8" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000593, HPA001341, CAB037264" Enhanced Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 48: Non-specific - RNA binding" "Cluster 1: T-cells - Immune response" Nucleoplasm "CAB037264: AB_477252, HPA000593: AB_1079348, HPA001341: AB_1079347" "unprognostic (1.27e-3)" "unprognostic (2.60e-3)" "unprognostic (2.16e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.35e-1)" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-2)" "unprognostic (8.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.84e-3)" "unprognostic (4.22e-1)" "prognostic favorable (7.32e-9)" "unprognostic (7.63e-2)" "unprognostic (1.00e-1)" "unprognostic (9.08e-2)" "unprognostic (6.05e-2)" MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Fibroblasts: 596.9;Peritubular cells: 231.7;Smooth muscle cells: 172.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cancer enhanced" "Detected in many" "Bone cancer: 116.5;Neuroblastoma: 110.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.9;Extravillous trophoblasts: 1260.6;Fibroblasts: 678.9;Syncytiotrophoblasts: 285.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "ovarian cancer: 94.1;testis cancer: 137.1" "Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.2;Kupffer cells: 211.1;Macrophages: 207.6;monocytes: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 560.6;Alveolar cells type 1: 955.9;Suprabasal keratinocytes: 363.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 1, Pancreas - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 646.2;Intestinal goblet cells: 236.6;Paneth cells: 471.1;Proximal enterocytes: 1075.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.9" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" MLIP "C6orf142, CIP, MGC18257" ENSG00000146147 "Muscular LMNA interacting protein" Q5VWP3 6 53929982-54266280 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 209.2;liver: 131.3;skeletal muscle: 246.6;tongue: 149.5" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 255.0;Excitatory neurons: 240.5;Skeletal myocytes: 113.8" "Group enriched" "Detected in some" 4 "glioma: 0.8;head and neck cancer: 0.5;liver cancer: 1.9;melanoma: 1.4" "Group enriched" "Detected in some" 5 "cerebral cortex: 15.4;hippocampal formation: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 9.7;thyroid cancer: 8.3" "Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029252, HPA046654, HPA077663" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 44: Myeloma - Humoral immune response" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Plasma membrane" Vesicles "HPA029252: AB_2732446, HPA046654: , HPA077663: " "unprognostic (7.95e-3)" "unprognostic (4.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.06e-4)" "unprognostic (2.38e-2)" "unprognostic (1.26e-2)" "unprognostic (5.60e-2)" "unprognostic (2.74e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.91e-5)" "unprognostic (7.49e-2)" "unprognostic (2.65e-2)" "unprognostic (5.27e-2)" "unprognostic (3.29e-3)" MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 78.6;Cholangiocytes: 32.7;Ductal cells: 106.7;Exocrine glandular cells: 66.2;Gastric mucus-secreting cells: 24.4;Pancreatic endocrine cells: 84.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ovarian cancer: 408.7;Sarcoma: 782.4;skin cancer: 588.5;thyroid cancer: 1539.1" "Pancreas - Ductal cells" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 17.6;Excitatory neurons: 24.2;Horizontal cells: 15.4;Inhibitory neurons: 37.5;Oligodendrocyte precursor cells: 12.0;Proximal tubular cells: 13.7;Thymic epithelial cells: 20.8" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 39.6" "Adipose visceral - Mesothelial cells, Colon - Smooth muscle cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 68: Kidney - Mixed function" "Cluster 37: Neurons - Neuronal signaling" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Group enriched" "Detected in many" 4 "Ductal cells: 7254.7;Exocrine glandular cells: 2226.2;Pancreatic endocrine cells: 4815.9" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 608.5;Uterine cancer: 464.7" "Liver - Cholangiocyte, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 329.5;Hofbauer cells: 104.2;Kupffer cells: 355.0;Macrophages: 210.1;monocytes: 236.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Group enriched" "Detected in some" 187 "Leukemia: 11.9;lymphoma: 27.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" MRAP2 "bA51G5.2, C6orf117" ENSG00000135324 "Melanocortin 2 receptor accessory protein 2" Q96G30 6 84033772-84090881 "Disease related genes, Human disease related genes, Predicted membrane proteins" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 13.8;Excitatory neurons: 55.7;Gastric mucus-secreting cells: 15.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.5" "Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (3.82e-4)" "unprognostic (7.11e-2)" "unprognostic (2.35e-1)" "prognostic favorable (1.66e-4)" "unprognostic (8.80e-3)" "unprognostic (3.15e-1)" "unprognostic (9.85e-2)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-3)" "unprognostic (1.41e-2)" "unprognostic (4.47e-1)" "unprognostic (6.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (4.50e-3)" "unprognostic (9.12e-2)" MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 125.9;Hofbauer cells: 159.5;Kupffer cells: 137.6;Langerhans cells: 208.6;Macrophages: 432.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Cancer enriched" "Detected in single" 8 "Rhabdoid: 8.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "granulocytes: 20.6;Kupffer cells: 6.3;Macrophages: 15.8;monocytes: 5.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.8" "Low cancer specificity" "Detected in all" "Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" HPA040075 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "dendritic cells: 427.6;Hofbauer cells: 531.2;Kupffer cells: 705.2;Langerhans cells: 553.8;Macrophages: 755.6;monocytes: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cancer enriched" "Detected in some" 11 "Leukemia: 17.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.7;Kupffer cells: 305.4;Macrophages: 613.9;monocytes: 1048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cancer enhanced" "Detected in some" "Leukemia: 7.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 4 "Hofbauer cells: 124.3;Kupffer cells: 81.6;Langerhans cells: 98.4;Macrophages: 193.1;monocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 19: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" MTMR7 ENSG00000003987 "Myotubularin related protein 7" Q9Y216 8 17296794-17413528 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;retina: 28.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 78.1;Inhibitory neurons: 113.7;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 162.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 6.9" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075682 Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 32: Neurons - Synaptic function" "Nucleoplasm, Cytosol" "HPA075682: " "unprognostic (1.01e-1)" "unprognostic (6.10e-2)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.31e-2)" "unprognostic (4.15e-2)" "unprognostic (1.41e-2)" "unprognostic (1.92e-1)" "unprognostic (2.45e-1)" "unprognostic (2.07e-4)" "unprognostic (1.46e-2)" "unprognostic (1.97e-7)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (2.66e-3)" MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 82.7;Enteroendocrine cells: 34.2;Intestinal goblet cells: 59.8;Paneth cells: 52.4;Proximal enterocytes: 140.4;Undifferentiated cells: 27.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.1;Leukemia: 23.4" "Kidney - Proximal tubular cells, Liver - Vascular Endothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" No No "Cluster 25: Monocytes - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 19: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 72.0;dendritic cells: 124.8;Hofbauer cells: 120.0;Kupffer cells: 115.9;Macrophages: 130.8;monocytes: 172.3;NK-cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Bone cancer: 60.2;Leukemia: 62.2;lymphoma: 52.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Supported "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" NCMAP "C1orf130, FLJ42528, MP11" ENSG00000184454 "Non-compact myelin associated protein" Q5T1S8 1 24556087-24609328 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "gallbladder: 7.3;pancreas: 8.5;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "dendritic cells: 16.1;Ductal cells: 19.1;Exocrine glandular cells: 33.2;Schwann cells: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.7" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 4 "spinal cord: 147.1" HPA013656 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 74: Pancreatic cells - Mixed function" "HPA013656: AB_2275006" "unprognostic (3.38e-2)" "unprognostic (3.52e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.83e-6)" "unprognostic (3.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.73e-1)" "unprognostic (2.41e-2)" "unprognostic (1.04e-1)" "unprognostic (3.28e-3)" "unprognostic (9.88e-2)" "unprognostic (9.53e-2)" "unprognostic (1.63e-2)" "unprognostic (7.27e-3)" NDRG4 "KIAA1180, SMAP-8" ENSG00000103034 "NDRG family member 4" Q9ULP0 16 58462846-58513628 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 380.7;heart muscle: 352.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.6;Excitatory neurons: 94.4;Horizontal cells: 298.7;Inhibitory neurons: 92.2;Muller glia cells: 72.5;Sertoli cells: 88.5" "Cancer enriched" "Detected in many" 6 "glioma: 23.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "Neuroblastoma: 62.9;Rhabdoid: 36.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015313, HPA017587" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 77: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA015313: AB_1854343, HPA017587: AB_1854344" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" "unprognostic (9.03e-3)" "unprognostic (1.59e-2)" "unprognostic (3.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (6.07e-2)" "unprognostic (1.02e-1)" "unprognostic (4.84e-3)" "unprognostic (5.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.22e-2)" "unprognostic (8.51e-2)" "unprognostic (4.45e-2)" "unprognostic (7.17e-2)" NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.8;Langerhans cells: 175.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478" "prognostic favorable (1.72e-5)" "unprognostic (1.43e-1)" "unprognostic (1.39e-2)" "unprognostic (2.37e-2)" "unprognostic (6.32e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (4.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (2.61e-2)" "unprognostic (8.83e-2)" "unprognostic (1.37e-2)" "prognostic favorable (8.07e-4)" NIPAL1 "DKFZp686A06115, NPAL1" ENSG00000163293 "NIPA like domain containing 1" Q6NVV3 4 47914142-48040173 "Predicted membrane proteins" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.8;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 39.4;Distal enterocytes: 49.6;Paneth cells: 38.4;Squamous epithelial cells: 52.6;Suprabasal keratinocytes: 77.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA036765 Uncertain Approved "Golgi apparatus" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA036765: AB_10672366" "unprognostic (3.03e-1)" "unprognostic (4.55e-2)" "unprognostic (2.34e-3)" "unprognostic (2.18e-2)" "unprognostic (1.12e-2)" "unprognostic (3.57e-1)" "unprognostic (9.55e-2)" "unprognostic (4.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (3.71e-3)" "unprognostic (1.34e-1)" "unprognostic (9.03e-7)" "unprognostic (2.55e-1)" "unprognostic (3.73e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.5;heart muscle: 18.3;pituitary gland: 18.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 192.7;Inhibitory neurons: 259.5;Late spermatids: 58.4;Oligodendrocyte precursor cells: 94.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.1;testis cancer: 25.1" "Breast - Endothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015708, HPA061714" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" Cytosol "HPA015708: , HPA061714: AB_2732669" "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 248.1;Endothelial cells: 123.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.1;Bipolar cells: 51.1;Endothelial cells: 34.9;Excitatory neurons: 21.4;Horizontal cells: 27.6;Inhibitory neurons: 20.5" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 10.5" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" NPR3 "ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC" ENSG00000113389 "Natriuretic peptide receptor 3" P17342 5 32689070-32791724 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 107.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 37.4;Cardiomyocytes: 33.7;Distal tubular cells: 37.3;Granulosa cells: 97.1;Proximal tubular cells: 131.6" "Cancer enhanced" "Detected in many" "renal cancer: 19.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "cervical cancer: 37.1" "Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052702 Supported Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol "HPA052702: AB_2681922" "unprognostic (8.56e-3)" "unprognostic (1.54e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (7.64e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-2)" "unprognostic (9.28e-2)" "unprognostic (6.78e-3)" "unprognostic (1.76e-1)" "unprognostic (6.07e-2)" "unprognostic (3.46e-3)" "prognostic favorable (5.43e-6)" "unprognostic (6.00e-4)" "unprognostic (5.74e-2)" "unprognostic (2.80e-2)" "unprognostic (3.38e-2)" NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 10.1;Pancreatic endocrine cells: 32.6;Sertoli cells: 11.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 62.9" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 55: Endocrine cells - Hormone signaling" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 3899.8;Excitatory neurons: 3156.4;Inhibitory neurons: 2058.1;Oligodendrocyte precursor cells: 4690.3" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "lung cancer: 4.1;Neuroblastoma: 4.1;thyroid cancer: 4.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 192.6;Cytotrophoblasts: 120.3;Granulosa cells: 124.0;Melanocytes: 426.7;Suprabasal keratinocytes: 146.3;Theca cells: 129.9" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.4;skin cancer: 66.8" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" NSG2 "CALY3, HMP19" ENSG00000170091 "Neuronal vesicle trafficking associated 2" Q9Y328 5 174045706-174243501 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 198.5" "Cell type enhanced" "Detected in some" "Early spermatids: 30.6;Excitatory neurons: 44.7;Horizontal cells: 92.3;Inhibitory neurons: 95.6;Oligodendrocyte precursor cells: 94.8" "Cancer enriched" "Detected in some" 8 "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Neuroblastoma: 165.1;thyroid cancer: 76.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046531, HPA056191" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" "HPA046531: AB_2732528, HPA056191: AB_2683062" "unprognostic (1.25e-2)" "unprognostic (1.36e-1)" "unprognostic (3.27e-1)" "unprognostic (3.36e-5)" "unprognostic (1.93e-1)" "unprognostic (2.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.07e-1)" "unprognostic (3.29e-1)" "unprognostic (1.76e-1)" "unprognostic (3.86e-3)" "unprognostic (8.06e-2)" "unprognostic (2.29e-2)" "unprognostic (3.02e-2)" "unprognostic (5.20e-2)" "unprognostic (9.31e-4)" "unprognostic (1.55e-1)" NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 47.2;Endometrial ciliated cells: 44.4;Glandular and luminal cells: 51.7;Intestinal goblet cells: 45.8;Suprabasal keratinocytes: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 45.6" "Pancreas - Ductal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 108.9;Fibroblasts: 181.8;Leydig cells: 166.5;Peritubular cells: 203.7;Thymic epithelial cells: 677.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 21.3" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 14.1;Fibroblasts: 46.2;Leydig cells: 42.3;Peritubular cells: 39.0;Smooth muscle cells: 18.9;Thymic epithelial cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 76.3;Leydig cells: 131.8;Peritubular cells: 159.5;Rod photoreceptor cells: 44.5;Thymic epithelial cells: 47.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812142-28871267 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 4.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 11.6;Inhibitory neurons: 15.5" "Cancer enhanced" "Detected in single" "melanoma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9;skin cancer: 4.4" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070831 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "HPA070831: AB_2732167" "unprognostic (1.44e-1)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-3)" "unprognostic (6.28e-3)" "unprognostic (5.92e-2)" "unprognostic (1.82e-2)" "unprognostic (5.95e-3)" "unprognostic (4.28e-3)" "unprognostic (2.98e-1)" "unprognostic (1.52e-7)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-3)" OR2I1P "HS6M1-14, OR2I1, OR2I2, OR2I3P, OR2I4P" ENSG00000237988 "Olfactory receptor family 2 subfamily I member 1 pseudogene" 6 29550407-29557721 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Rod photoreceptor cells: 2.4" "Cancer enhanced" "Detected in all" "liver cancer: 71.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - T-cells, Pancreas - Ductal cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 18: Non-specific - Mixed function" "unprognostic (7.45e-3)" "unprognostic (1.69e-2)" "unprognostic (6.00e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.60e-2)" "unprognostic (1.07e-3)" "unprognostic (3.29e-1)" "unprognostic (2.23e-1)" "unprognostic (5.34e-3)" "prognostic favorable (5.58e-4)" "unprognostic (1.32e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (4.00e-6)" "unprognostic (8.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-2)" OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 32.5;Leydig cells: 133.8;Peritubular cells: 43.0;Thymic epithelial cells: 96.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 9.6;Gastric cancer: 9.2;Sarcoma: 10.0" "Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cancer enhanced" "Detected in some" "Rhabdoid: 8.7" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" OXTR ENSG00000180914 "Oxytocin receptor" P30559 3 8750381-8769628 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 14.7;breast: 54.1" "Cell type enriched" "Detected in many" 6 "Breast myoepithelial cells: 160.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Bladder cancer: 30.6" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.18e-1)" "unprognostic (7.94e-2)" "unprognostic (4.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (2.02e-1)" "unprognostic (1.46e-2)" "unprognostic (2.56e-3)" "unprognostic (2.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.76e-1)" "unprognostic (3.80e-2)" "unprognostic (4.24e-4)" "unprognostic (8.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" P2RX2 "DFNA41, P2X2" ENSG00000187848 "Purinergic receptor P2X 2" Q9UBL9 12 132618776-132622388 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;epididymis: 21.8;prostate: 14.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 4.1;Breast glandular cells: 1.6;Endometrial ciliated cells: 2.3;Fibroblasts: 5.0;Gastric mucus-secreting cells: 1.2;Pancreatic endocrine cells: 3.4;Peritubular cells: 2.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Group enriched" "Detected in many" 7 "amygdala: 9.2;cerebral cortex: 11.3;hippocampal formation: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 5.5" "Colon - Fibroblasts, Pancreas - Beta cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 61: Non-specific - Transcription" "unprognostic (1.12e-1)" "unprognostic (1.49e-2)" "unprognostic (5.92e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (3.12e-1)" "unprognostic (5.79e-3)" "unprognostic (6.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.11e-2)" "unprognostic (3.66e-2)" "unprognostic (1.88e-2)" "unprognostic (6.21e-2)" "unprognostic (3.05e-1)" "unprognostic (9.12e-2)" P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.2;Excitatory neurons: 8.8;Horizontal cells: 10.9;Inhibitory neurons: 7.8;Oligodendrocyte precursor cells: 4.8;Skeletal myocytes: 5.9" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 4.2" "Liver - Hepatic stellate cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;lymphoid tissue: 9.8" "Cell type enriched" "Detected in some" 21 "Microglial cells: 410.5" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Not detected" "Not detected" "Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" "HPA013796: AB_1854884, HPA014518: AB_2669027" "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 68.3" "Group enriched" "Detected in some" 8 "Enteroendocrine cells: 178.7;Excitatory neurons: 53.7;Pancreatic endocrine cells: 56.7" "Cancer enhanced" "Detected in many" "breast cancer: 12.1" "Group enriched" "Detected in all" 5 "cerebral cortex: 19.1;hypothalamus: 68.3;pons: 30.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 31.7;thyroid cancer: 72.7" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 55: Endocrine cells - Hormone signaling" "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549601-54579239 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 76.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.3;Hofbauer cells: 8.0;Horizontal cells: 11.5;Inhibitory neurons: 10.0;Kupffer cells: 8.7;Macrophages: 9.6;Smooth muscle cells: 11.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 76.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bone cancer: 8.7;Leukemia: 8.5;lymphoma: 7.0;Myeloma: 2.7" "Breast - Adipocytes (Breast), Pancreas - Endothelial cells" "Region enriched" "Detected in all" 6 "basal ganglia: 999.4" "Region enriched" "Detected in all" 7 "basal ganglia: 228.7" HPA018492 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: Bone cancer - Transcription" "Cluster 72: Smooth muscle cells - ECM organization" "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" PDZD3 "FLJ22756, IKEPP, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 19.3;kidney: 17.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 58.7;Gastric mucus-secreting cells: 27.4;Paneth cells: 30.3;Proximal enterocytes: 67.4;Proximal tubular cells: 26.7;Undifferentiated cells: 16.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.3;renal cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA077887 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA077887: " "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (6.07e-2)" "unprognostic (3.22e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-3)" "unprognostic (9.00e-2)" "unprognostic (6.08e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.41e-3)" PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.3;Kupffer cells: 5.4;Macrophages: 2.0;monocytes: 2.2;NK-cells: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Not detected" "Not detected" "Colon - Macrophages, Pancreas - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" PHF21B "BHC80L, FLJ34161, PHF4" ENSG00000056487 "PHD finger protein 21B" Q96EK2 22 44881162-45010005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.9" "Cell type enhanced" "Detected in some" "Astrocytes: 93.6;Late spermatids: 44.8;Oligodendrocyte precursor cells: 27.9;Rod photoreceptor cells: 28.3" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 41.7" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053834, HPA074665" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA053834: AB_2682276, HPA074665: " "unprognostic (1.04e-1)" "unprognostic (7.76e-2)" "unprognostic (2.00e-1)" "unprognostic (7.44e-2)" "unprognostic (1.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (1.86e-3)" "unprognostic (2.02e-1)" "unprognostic (9.35e-2)" "unprognostic (2.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.22e-1)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Group enriched" "Detected in many" 5 "Fibroblasts: 173.6;Leydig cells: 203.7;Oligodendrocytes: 63.6;Peritubular cells: 144.5" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cancer enriched" "Detected in some" 8 "Kidney cancer: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 130.8;Inhibitory neurons: 138.3;Langerhans cells: 264.8;Microglial cells: 175.1;Oligodendrocyte precursor cells: 520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4" "Cell type enhanced" "Detected in some" "dendritic cells: 34.9;Kupffer cells: 34.8;Langerhans cells: 47.6;Macrophages: 39.6;Microglial cells: 77.5;monocytes: 38.6;NK-cells: 36.9;Schwann cells: 25.4;T-cells: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 11.2;lymphoma: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "Centriolar satellite" "HPA044505: AB_2678964, HPA052247: AB_2681772, HPA052412: AB_2681823" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (9.89e-3)" "unprognostic (1.42e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" "unprognostic (6.89e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 12 "Adipocytes: 460.8;Endothelial cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Group enriched" "Detected in some" 15 "Leukemia: 10.6;lymphoma: 2.9;ovarian cancer: 7.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.2;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 21.9;Late spermatids: 13.5;Respiratory ciliated cells: 8.3;Spermatocytes: 13.6;Spermatogonia: 14.1" "Cancer enhanced" "Detected in many" "testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gastric cancer: 2.1" "Pancreas - Ductal cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA052026 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Enzymes" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA052026: AB_2681699" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" PNMA2 "MA2, RGAG2" ENSG00000240694 "PNMA family member 2" Q9UL42 8 26504701-26514092 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;retina: 24.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.3;Excitatory neurons: 70.2;Horizontal cells: 39.1;Inhibitory neurons: 89.7;Muller glia cells: 24.6" "Cancer enhanced" "Detected in many" "glioma: 28.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001936 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 14: Bone cancer - Transcription" "Cluster 37: Neurons - Neuronal signaling" "HPA001936: AB_1079647" "unprognostic (1.25e-2)" "unprognostic (1.27e-2)" "unprognostic (6.39e-2)" "unprognostic (1.43e-6)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" "unprognostic (8.76e-2)" "prognostic favorable (1.81e-4)" "unprognostic (4.66e-2)" "unprognostic (1.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.12e-2)" "unprognostic (4.58e-5)" "unprognostic (9.00e-3)" PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 168.0;Cardiomyocytes: 95.4;Respiratory ciliated cells: 62.3;Skeletal myocytes: 120.7;Suprabasal keratinocytes: 187.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 36.2" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.2" "Cell type enhanced" "Detected in many" "Astrocytes: 59.2;Early spermatids: 61.7;Excitatory neurons: 200.4;Inhibitory neurons: 80.9;Late spermatids: 185.7;Oligodendrocytes: 89.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155, HPA060473: AB_2684291" "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavorable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386439 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;thyroid gland: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 42.5;Distal enterocytes: 34.1;Excitatory neurons: 44.6;Microglial cells: 33.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 35.0" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "HPA011776, HPA012066" Uncertain Uncertain "Nucleoli,Focal adhesion sites" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" Nucleoli "Focal adhesion sites" "HPA011776: , HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Fibroblasts: 257.0;Leydig cells: 98.4;Melanocytes: 323.9;Muller glia cells: 150.0;Peritubular cells: 202.9;Smooth muscle cells: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Brain cancer: 4.5;testis cancer: 5.2" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enriched" "Detected in some" 4 "NK-cells: 1120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cancer enriched" "Detected in some" 7 "lymphoma: 61.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" PSD "EFA6, EFA6A, KIAA2011, PSD1, TYL" ENSG00000059915 "Pleckstrin and Sec7 domain containing" A5PKW4 10 102402617-102421539 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 233.9;intestine: 261.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 47.0;Cone photoreceptor cells: 53.4;Endometrial stromal cells: 50.0;Excitatory neurons: 40.6;Horizontal cells: 24.4;Inhibitory neurons: 29.2;Rod photoreceptor cells: 69.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.2" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059237 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA059237: AB_2683954" "unprognostic (2.43e-1)" "unprognostic (1.74e-1)" "unprognostic (5.62e-3)" "unprognostic (1.53e-1)" "unprognostic (3.16e-2)" "unprognostic (2.90e-2)" "unprognostic (7.73e-3)" "unprognostic (1.75e-1)" "unprognostic (9.59e-2)" "unprognostic (7.59e-2)" "unprognostic (2.24e-3)" "unprognostic (4.71e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (8.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "placenta: 111.8" "Cell type enriched" "Detected in some" 39 "Syncytiotrophoblasts: 702.8" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Region enhanced" "Detected in single" "cerebellum: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" HPA046327 Supported "Secreted in female reproductive system" NA NA 22000000 "Cluster 28: Placenta - Pregnancy" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (1.59e-1)" "unprognostic (3.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.12e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.92e-2)" PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 80.7;urinary bladder: 81.7" "Cell type enriched" "Detected in many" 4 "Thymic epithelial cells: 448.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.4" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 91.4;Langerhans cells: 177.8;Melanocytes: 668.8;Pancreatic endocrine cells: 152.9" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Group enriched" "Detected in all" 5 "Myeloma: 105.5;skin cancer: 252.9" "Lung - Neutrophil_2, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 25: Schwann cells & Melanocytes - Mixed function" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" RAB32 ENSG00000118508 "RAB32, member RAS oncogene family" Q13637 6 146543833-146554953 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 175.1" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 228.8;granulocytes: 217.6;Hofbauer cells: 239.7;Melanocytes: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 86.5" "Group enriched" "Detected in many" 42 "dendritic cells: 42.5;granulocytes: 86.5;monocytes: 46.8" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Testis - Early spermatids" HPA025731 Approved Approved Cytosol NA NA 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 4: Platelets - Platelet activation" Cytosol "HPA025731: AB_1856001" "unprognostic (3.07e-1)" "unprognostic (5.32e-2)" "prognostic favorable (1.56e-4)" "prognostic unfavorable (6.51e-4)" "unprognostic (1.26e-1)" "unprognostic (2.34e-3)" "prognostic unfavorable (1.08e-7)" "unprognostic (2.64e-2)" "unprognostic (9.71e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" RADX "CXorf57, FLJ10178, FLJ14191" ENSG00000147231 "RPA1 related single stranded DNA binding protein, X-linked" Q6NSI4 X 106611930-106679439 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3;pituitary gland: 20.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 12.1;Oligodendrocyte precursor cells: 14.4;Spermatogonia: 12.1;Syncytiotrophoblasts: 20.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 1.8;NK-cells: 1.0;T-cells: 1.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Alpha cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000896, HPA001010, HPA001374" Uncertain Supported "Nuclear speckles" NA No "Cluster 40: NK-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 47: Retina - Visual perception" "Cluster 1: T-cells - Immune response" "Nuclear speckles" "HPA000896: AB_1078880, HPA001010: , HPA001374: AB_2666288" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (4.85e-2)" "unprognostic (8.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-1)" "unprognostic (5.49e-2)" "unprognostic (3.81e-3)" "unprognostic (1.17e-1)" "unprognostic (4.20e-3)" "unprognostic (1.63e-1)" "unprognostic (2.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.23e-3)" RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 218.0;Inhibitory neurons: 398.2;Microglial cells: 86.7;Oligodendrocytes: 373.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 12630.5" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "liver cancer: 210.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Macrophages, Pancreas - Beta cells, Skin - Adipocytes (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 364.2" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 17.6;liver cancer: 11.0;Myeloma: 10.7" "Pancreas - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 68: Kidney - Mixed function" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.5;Astrocytes: 170.5;Endothelial cells: 70.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;skin cancer: 36.2" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" RIIAD1 "C1orf230, FLJ36032, NCRNA00166" ENSG00000178796 "Regulatory subunit of type II PKA R-subunit domain containing 1" A6NNX1 1 151710433-151729805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "fallopian tube: 24.9;pituitary gland: 34.7;testis: 16.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 86.2;Early spermatids: 88.0;Endometrial ciliated cells: 141.9;Enteroendocrine cells: 35.3;Late spermatids: 56.3;Respiratory ciliated cells: 92.6" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "Neuroblastoma: 7.9" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA045703 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 56: Ciliated cells - Cilium assembly" Cytosol Nucleoplasm "HPA045703: AB_10965795" "unprognostic (8.28e-3)" "unprognostic (3.42e-1)" "unprognostic (8.21e-2)" "prognostic favorable (5.46e-4)" "unprognostic (1.06e-2)" "unprognostic (3.09e-1)" "unprognostic (8.99e-2)" "unprognostic (3.20e-3)" "unprognostic (3.95e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-3)" "unprognostic (8.50e-2)" "unprognostic (1.57e-3)" "unprognostic (2.79e-2)" "unprognostic (3.06e-2)" "unprognostic (2.48e-4)" RIPPLY2 "C6orf159, dJ237I15.1" ENSG00000203877 "Ripply transcriptional repressor 2" Q5TAB7 6 83853266-83857515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.2;choroid plexus: 9.6;pituitary gland: 11.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 8.9;Cone photoreceptor cells: 8.6;Excitatory neurons: 9.9;Horizontal cells: 10.3;Inhibitory neurons: 10.2;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 4.3;Pancreatic endocrine cells: 5.2;Rod photoreceptor cells: 7.3;Spermatogonia: 4.0" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047454 Uncertain NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "HPA047454: AB_2680053" "unprognostic (2.09e-1)" "unprognostic (7.43e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-3)" "unprognostic (2.69e-3)" "unprognostic (3.66e-1)" "unprognostic (6.94e-3)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 20.2;Endothelial cells: 18.7;Fibroblasts: 49.6;Inhibitory neurons: 17.3;Leydig cells: 27.9;Smooth muscle cells: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.2;Rhabdoid: 19.5" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 61: Liver - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 288.0" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 947.8;Rod photoreceptor cells: 453.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 13.6" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: Myeloma - Humoral immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.2;Enteroendocrine cells: 22.1;Excitatory neurons: 45.5;Horizontal cells: 44.2;Inhibitory neurons: 29.7;Late spermatids: 84.7" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 46.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 261.4;Endothelial cells: 153.5;NK-cells: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 21.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 5 "NK-cells: 253.7;T-cells: 72.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - Alpha cells, Prostate - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 7: NK-cells - Immune response regulation" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.3;Endothelial cells: 47.7;Langerhans cells: 45.1;Microglial cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2568.4;Glandular and luminal cells: 2598.6" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 17.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Group enriched" "Detected in many" 7 "B-cells: 78.9;Hofbauer cells: 42.8;Kupffer cells: 89.4;Macrophages: 63.9;monocytes: 119.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cancer enhanced" "Detected in many" "lymphoma: 15.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.0;Club cells: 26.4;Collecting duct cells: 41.4;Gastric mucus-secreting cells: 14.9;Glandular and luminal cells: 16.7;Ionocytes: 17.9;Salivary duct cells: 27.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 15.9" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 14: Bone cancer - Transcription" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 580.4;Exocrine glandular cells: 797.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 295.4;Kupffer cells: 92.0;Macrophages: 68.4;monocytes: 178.2;NK-cells: 166.0;T-cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 33 "Leukemia: 71.3;lymphoma: 66.0;Myeloma: 244.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in many" "B-cells: 98.3;NK-cells: 87.5;T-cells: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 58 "Leukemia: 27.5;lymphoma: 32.6;Myeloma: 19.8" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 219.9" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 29: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 241.9;Cholangiocytes: 363.8;Endometrial ciliated cells: 146.2;Glandular and luminal cells: 335.7;Hepatocytes: 176.9;Late spermatids: 275.7;Peritubular cells: 142.4;Sertoli cells: 362.1" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 25.5;liver cancer: 63.9" "Liver - Hepatocytes, Pancreas - Macrophages, Skin - Fibroblast_2, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Group enriched" "Detected in many" 8 "Basal keratinocytes: 1551.5;Suprabasal keratinocytes: 672.5;Syncytiotrophoblasts: 692.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 317.0" "Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" SEZ6 ENSG00000063015 "Seizure related 6 homolog" Q53EL9 17 28954901-29006440 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 54.7;pituitary gland: 15.8;retina: 27.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 61.6;Cone photoreceptor cells: 22.4;Excitatory neurons: 15.6;Horizontal cells: 70.5;Inhibitory neurons: 23.8;Rod photoreceptor cells: 21.1" "Cancer enriched" "Detected in many" 11 "glioma: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.1;neutrophil: 2.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "lung cancer: 12.4;Neuroblastoma: 13.4;thyroid cancer: 20.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011777 Enhanced NA NA 310000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" "HPA011777: AB_1856758" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (5.75e-3)" "unprognostic (5.33e-3)" "unprognostic (1.84e-2)" "unprognostic (1.76e-3)" "unprognostic (2.82e-2)" "unprognostic (2.22e-2)" "unprognostic (3.07e-1)" "unprognostic (4.75e-2)" "unprognostic (1.22e-3)" "unprognostic (3.15e-3)" "unprognostic (3.63e-6)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 218.7;Inhibitory neurons: 134.3;Oligodendrocyte precursor cells: 561.3" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 4 "Bone cancer: 25.6;lung cancer: 7.0;Neuroblastoma: 22.1" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 354.3;Cardiomyocytes: 142.1;Excitatory neurons: 190.3;Inhibitory neurons: 157.2;Microglial cells: 121.3;Oligodendrocyte precursor cells: 399.5;Oligodendrocytes: 185.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 10.9" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 116.5;Alveolar cells type 2: 122.6;Endometrial ciliated cells: 167.6;Glandular and luminal cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015076, HPA015541" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 14: Endometrium - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA015076: AB_1857298, HPA015541: " "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 48.6;dendritic cells: 36.0;Endothelial cells: 52.0;Microglial cells: 22.8;monocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 33.7;lymphoma: 25.7;Myeloma: 27.6;Neuroblastoma: 16.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 53.6;Alveolar cells type 1: 21.8;Endothelial cells: 77.6;Late spermatids: 21.5;Microglial cells: 25.5;Spermatocytes: 27.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.9;Alveolar cells type 2: 9.4;Cholangiocytes: 15.4;Collecting duct cells: 7.9;Gastric mucus-secreting cells: 10.1;Glandular and luminal cells: 8.4;Hepatocytes: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 121.3;Oligodendrocytes: 437.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 4.5;testis cancer: 3.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Hofbauer cells: 77.2;Macrophages: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Group enriched" "Detected in some" 4 "Hofbauer cells: 23.6;Kupffer cells: 47.9;Macrophages: 20.3;monocytes: 27.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Cancer enriched" "Detected in single" 7 "Leukemia: 4.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Group enriched" "Detected in some" 5 "Hofbauer cells: 36.7;Kupffer cells: 39.7;Macrophages: 33.3;monocytes: 16.7;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 4.0;Myeloma: 5.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;lymphoid tissue: 6.8" "Group enriched" "Detected in some" 17 "granulocytes: 30.0;Macrophages: 11.2;Microglial cells: 10.9" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.2" "Lineage enriched" "Detected in single" 719 "granulocytes: 290.2" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.5" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Pancreas - Macrophages, Skin - Mast cells" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 62: Granulocytes - Innate immune response" "Cluster 69: Macrophages - Innate immune response" Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 8.0;Kupffer cells: 17.3;Langerhans cells: 4.0;Macrophages: 11.8;Microglial cells: 13.7;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" SIRPG "bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma" ENSG00000089012 "Signal regulatory protein gamma" Q9P1W8 20 1629152-1657779 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 39.1" "Group enriched" "Detected in some" 4 "Early spermatids: 63.4;T-cells: 39.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 369.4" "Lineage enriched" "Detected in many" 6 "T-cells: 369.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;ovarian cancer: 2.2;thyroid cancer: 4.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.35e-3)" "unprognostic (4.09e-3)" "unprognostic (7.32e-3)" "prognostic favorable (1.05e-6)" "unprognostic (4.23e-3)" "prognostic favorable (2.24e-4)" "unprognostic (4.49e-2)" "unprognostic (1.30e-2)" "prognostic favorable (7.36e-7)" "unprognostic (1.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.40e-2)" "unprognostic (2.95e-3)" SIX3 HPE2 ENSG00000138083 "SIX homeobox 3" O95343 2 44941702-44946071 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 22.7;choroid plexus: 12.2;parathyroid gland: 9.1;pituitary gland: 27.8;retina: 25.3" "Group enriched" "Detected in some" 16 "Bipolar cells: 153.5;Horizontal cells: 165.3;Muller glia cells: 317.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 12.4" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 38.7;hypothalamus: 19.5" HPA067988 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 68: Muller glia cells - Visual perception" Nucleoplasm "HPA067988: AB_2685939" "unprognostic (1.19e-3)" "unprognostic (1.05e-2)" "unprognostic (4.76e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-2)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (6.82e-2)" "unprognostic (1.22e-1)" "unprognostic (2.49e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-2)" SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.6;Kupffer cells: 202.1;Macrophages: 156.4;monocytes: 190.1;NK-cells: 323.6;T-cells: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Leukemia: 36.4;lymphoma: 23.9;Myeloma: 17.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Deafness, Disease variant, FDA approved drug targets, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 315.0;Oligodendrocytes: 534.9;Undifferentiated cells: 342.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "colorectal cancer: 97.7" "Adipose visceral - Endothelial cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "Vesicles, Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" SLC12A5 "KCC2, KIAA1176" ENSG00000124140 "Solute carrier family 12 member 5" Q9H2X9 20 46021690-46060150 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 145.8;retina: 117.4" "Group enriched" "Detected in many" 6 "Bipolar cells: 212.2;Cone photoreceptor cells: 253.3;Excitatory neurons: 91.5;Horizontal cells: 132.0;Inhibitory neurons: 89.1;Rod photoreceptor cells: 195.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072058 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 9: Neurons - Nervous system development" "HPA072058: AB_2686485" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" "unprognostic (9.44e-4)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.48e-1)" "unprognostic (5.16e-3)" "unprognostic (3.61e-1)" "unprognostic (2.49e-1)" "unprognostic (6.63e-2)" "unprognostic (3.72e-3)" "unprognostic (5.61e-4)" "unprognostic (8.78e-4)" "unprognostic (3.25e-2)" "unprognostic (9.22e-2)" "unprognostic (1.99e-1)" "unprognostic (2.34e-2)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 186.9;Cone photoreceptor cells: 81.0;Rod photoreceptor cells: 70.1" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Group enriched" "Detected in some" 5 "Brain cancer: 4.9;breast cancer: 9.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" SLC22A17 "BOCT, BOIT, NGALR" ENSG00000092096 "Solute carrier family 22 member 17" Q8WUG5 14 23346306-23352912 "Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 304.0;choroid plexus: 372.6;pituitary gland: 149.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 139.7;Inhibitory neurons: 108.3;Oligodendrocyte precursor cells: 115.5;Prostatic glandular cells: 144.3;Rod photoreceptor cells: 75.0" "Cancer enhanced" "Detected in all" "glioma: 51.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 29.1" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002728 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "HPA002728: AB_1079998" "unprognostic (9.34e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.23e-3)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.31e-2)" "unprognostic (1.26e-2)" "unprognostic (4.23e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.73e-4)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (3.50e-2)" "unprognostic (1.23e-2)" "unprognostic (3.87e-2)" SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 8 "Astrocytes: 130.3;Inhibitory neurons: 317.1;Oligodendrocyte precursor cells: 359.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Group enriched" "Detected in many" 5 "Bile duct cancer: 6.0;Bone cancer: 15.3;breast cancer: 13.1" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 57.4;Macrophages: 32.9;monocytes: 20.8;Serous glandular cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 40.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 69: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.3;choroid plexus: 121.4;retina: 34.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 595.7;Inhibitory neurons: 548.9" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.3" "Lineage enriched" "Detected in single" 65 "T-cells: 63.3" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;lymphoma: 1.3;prostate cancer: 2.0" "Adipose visceral - T-cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" "HPA034755: AB_10670296, HPA076725: " "unprognostic (4.64e-4)" "unprognostic (3.88e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "unprognostic (7.89e-3)" "unprognostic (5.99e-4)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" "unprognostic (5.65e-2)" "unprognostic (9.23e-3)" "unprognostic (1.87e-1)" "unprognostic (2.10e-3)" "unprognostic (2.26e-1)" SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 232.0" "Group enriched" "Detected in many" 10 "Cytotrophoblasts: 120.7;Proximal enterocytes: 101.8;Syncytiotrophoblasts: 96.9" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Group enriched" "Detected in some" 11 "midbrain: 232.0;pons: 86.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8;liver cancer: 1.7" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 7 "midbrain: 38.9;pons: 29.1" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: BEWO - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (7.45e-2)" "unprognostic (7.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.72e-4)" "unprognostic (2.07e-1)" "unprognostic (8.42e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-3)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (4.98e-2)" "unprognostic (1.76e-1)" "unprognostic (4.05e-2)" "unprognostic (7.18e-2)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 253.9;Inhibitory neurons: 534.8;Oligodendrocytes: 149.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 25.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 199.3;Fibroblasts: 112.0;Smooth muscle cells: 101.1;Thymic epithelial cells: 48.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1580.8;intestine: 753.9;kidney: 844.8" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 4278.4;Proximal tubular cells: 1491.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.7;pancreatic cancer: 37.4;renal cancer: 78.4;stomach cancer: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Gastric cancer: 34.8;Leukemia: 93.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm Cytosol "HPA045046: AB_10964444, HPA056027: AB_2683012" "unprognostic (2.18e-4)" "unprognostic (4.63e-1)" "unprognostic (5.68e-2)" "unprognostic (9.60e-2)" "unprognostic (1.93e-1)" "unprognostic (6.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.13e-10)" "unprognostic (1.68e-2)" "unprognostic (2.14e-1)" "unprognostic (8.36e-2)" "unprognostic (3.11e-2)" SMIM32 ENSG00000271824 "Small integral membrane protein 32" A0A1B0GUA5 5 136191468-136193162 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "brain: 17.7;intestine: 12.9;kidney: 49.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 384.3" "Cancer enhanced" "Detected in many" "renal cancer: 12.4" "Group enriched" "Detected in many" 6 "basal ganglia: 17.7;cerebral cortex: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;liver cancer: 2.1;thyroid cancer: 2.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (2.35e-5)" "unprognostic (3.08e-1)" "unprognostic (7.74e-2)" "unprognostic (7.79e-2)" "unprognostic (2.11e-2)" "unprognostic (9.13e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.86e-2)" "unprognostic (1.75e-2)" "prognostic favorable (6.13e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-3)" "unprognostic (8.05e-2)" SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 324.4;Peritubular cells: 769.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.3" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" SOGA3 "C6orf174, dJ403A15.3" ENSG00000214338 "SOGA family member 3" Q5TF21 6 127472794-127519191 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6" "Group enriched" "Detected in some" 9 "Excitatory neurons: 77.0;Inhibitory neurons: 56.1;Oligodendrocyte precursor cells: 42.4;Oligodendrocytes: 31.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 26.9" "Lung - Alveolar cells type 1, Pancreas - Beta cells, Testis - Early spermatids" "HPA035388, HPA035389" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA035388: AB_2674601, HPA035389: AB_10669857" "unprognostic (1.70e-1)" "unprognostic (3.56e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.19e-1)" "unprognostic (8.58e-3)" "unprognostic (8.45e-2)" "unprognostic (7.31e-4)" "unprognostic (5.65e-3)" "unprognostic (1.58e-1)" "unprognostic (3.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.30e-2)" "unprognostic (1.72e-1)" "unprognostic (8.26e-3)" SORBS3 "SCAM-1, SH3D4, vinexin" ENSG00000120896 "Sorbin and SH3 domain containing 3" O60504 8 22544986-22575788 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 135.1;Late spermatids: 482.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015849 Approved Uncertain "Focal adhesion sites,Cytosol" NA NA 7700 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol "Focal adhesion sites" "HPA015849: AB_1857365" "unprognostic (6.15e-3)" "unprognostic (2.09e-2)" "unprognostic (2.34e-1)" "unprognostic (3.90e-3)" "unprognostic (1.72e-1)" "unprognostic (9.30e-2)" "unprognostic (2.51e-2)" "unprognostic (2.44e-2)" "unprognostic (5.83e-3)" "unprognostic (1.70e-1)" "prognostic favorable (4.88e-4)" "unprognostic (4.21e-2)" "unprognostic (3.08e-3)" "unprognostic (7.41e-2)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.53e-5)" SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Cell type enriched" "Detected in some" 33 "Enteroendocrine cells: 4790.0" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 133.3;thyroid cancer: 474.4" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Inner root sheath cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 55: Endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0;intestine: 13.8;stomach 1: 21.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 8.5;Enteroendocrine cells: 25.5;Gastric mucus-secreting cells: 18.5;Oligodendrocyte precursor cells: 23.1;Paneth cells: 11.3;Proximal enterocytes: 11.1" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.0;Enteroendocrine cells: 47.7;Horizontal cells: 77.5;Mucus glandular cells: 27.1;Smooth muscle cells: 45.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 23.3" "Breast - Endothelial cells, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 328.1;Intestinal goblet cells: 182.4;Paneth cells: 166.7;Proximal enterocytes: 205.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Colon enterocytes, Heart muscle - Macrophages, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 26: Intestinal epithelial cells - Absorption" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" ST18 "KIAA0535, NZF-3, NZF3, ZC2H2C3, ZC2HC10, ZNF387" ENSG00000147488 "ST18 C2H2C-type zinc finger transcription factor" O60284 8 52110839-52460959 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 82.1" "Cell type enriched" "Detected in some" 43 "Oligodendrocytes: 3828.2" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.8" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Region enhanced" "Detected in all" "cerebellum: 40.2" "Low region specificity" "Detected in all" HPA044919 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "HPA044919: AB_10959756" "unprognostic (3.66e-1)" "unprognostic (4.34e-2)" "unprognostic (7.47e-2)" "unprognostic (2.04e-2)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-3)" "unprognostic (2.82e-1)" "unprognostic (2.53e-5)" "unprognostic (3.29e-1)" "unprognostic (1.35e-1)" "unprognostic (9.34e-2)" "unprognostic (9.84e-3)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Group enriched" "Detected in many" 5 "Endothelial cells: 127.8;Fibroblasts: 127.2;Hofbauer cells: 147.9;Kupffer cells: 242.8;Macrophages: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Cancer enriched" "Detected in single" 64 "Leukemia: 14.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 169.0;Distal enterocytes: 307.2;Paneth cells: 321.4;Proximal enterocytes: 441.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 7.9;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Ductal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 128.5;pituitary gland: 98.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 30.0;Excitatory neurons: 59.8;Pancreatic endocrine cells: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Alpha cells, Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "amygdala: 246.2;basal ganglia: 93.9;cerebral cortex: 354.4;hippocampal formation: 229.1;white matter: 116.1" "Group enriched" "Detected in all" 8 "amygdala: 37.6;cerebral cortex: 103.4;hippocampal formation: 87.2" "CAB008372, HPA069176" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 26: NCI-H716 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" Vesicles "Nuclear membrane" "CAB008372: AB_592786, HPA069176: AB_2686098" "unprognostic (5.12e-3)" "prognostic unfavorable (3.63e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.02e-8)" "unprognostic (1.11e-2)" "unprognostic (6.97e-2)" "unprognostic (3.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.70e-3)" "unprognostic (4.18e-6)" "unprognostic (2.65e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-3)" "unprognostic (6.20e-2)" SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 87.0;Excitatory neurons: 62.5;Horizontal cells: 166.0;Inhibitory neurons: 104.7" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" SYP MRX96 ENSG00000102003 Synaptophysin P08247 X 49187815-49200199 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 259.4;pituitary gland: 106.8;retina: 316.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 478.9;Cone photoreceptor cells: 468.7;Horizontal cells: 239.7;Rod photoreceptor cells: 599.0" "Group enriched" "Detected in many" 6 "glioma: 12.8;pancreatic cancer: 5.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 56.0" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000076, HPA002858, CAB055505, CAB078999, HPA079659" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 58: Brain - Synaptic function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" "CAB000076: AB_2315411, CAB055505: AB_564017, CAB078999: , HPA002858: AB_1080153, HPA079659: " "unprognostic (2.08e-1)" "unprognostic (8.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.37e-3)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.87e-1)" "unprognostic (6.46e-5)" "unprognostic (8.52e-3)" "unprognostic (1.62e-1)" "unprognostic (3.44e-3)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.94e-1)" SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 255.9" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 65.1" "Heart muscle - Cardiomyocytes, Liver - Cholangiocyte, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Enzymes" "Cluster 55: Endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;retina: 1.9;testis: 3.2;thyroid gland: 5.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 205.7;Inhibitory neurons: 209.0;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 186.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.7" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Asthma, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Group enriched" "Detected in some" 10 "NK-cells: 128.0;T-cells: 42.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Group enriched" "Detected in some" 13 "Leukemia: 1.8;lymphoma: 4.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 49.2;Hofbauer cells: 110.0;Kupffer cells: 175.8;Macrophages: 137.3;Microglial cells: 186.1;monocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 15.9;Leukemia: 16.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 67.3;choroid plexus: 35.5;pituitary gland: 62.2;retina: 23.5;testis: 60.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.5;Muller glia cells: 62.4;Peritubular cells: 35.3;Sertoli cells: 210.1" "Cancer enhanced" "Detected in many" "glioma: 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 22.7" "Heart muscle - Fibroblasts, Pancreas - Alpha cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (1.30e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (9.68e-2)" "unprognostic (8.75e-4)" "unprognostic (1.21e-1)" "unprognostic (8.11e-2)" "prognostic favorable (8.60e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.74e-1)" "unprognostic (6.30e-2)" "unprognostic (6.03e-4)" TCERG1L FLJ38950 ENSG00000176769 "Transcription elongation regulator 1 like" Q5VWI1 10 131092391-131311721 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;retina: 6.1;thyroid gland: 14.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 69.0;Horizontal cells: 33.3;Inhibitory neurons: 14.1;Melanocytes: 13.9" "Cancer enriched" "Detected in some" 14 "thyroid cancer: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 7.1;prostate cancer: 3.7" "Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030816 Approved Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA030816: AB_10601721" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "unprognostic (8.99e-2)" "unprognostic (1.45e-2)" "unprognostic (3.03e-1)" "unprognostic (6.69e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-1)" "unprognostic (9.71e-2)" "unprognostic (2.02e-1)" "unprognostic (5.01e-2)" "unprognostic (1.08e-5)" "unprognostic (1.28e-1)" "unprognostic (2.83e-1)" "unprognostic (2.96e-2)" "unprognostic (2.03e-1)" TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "salivary gland: 776.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 78.9;Club cells: 75.5;Exocrine glandular cells: 129.8;Glandular and luminal cells: 109.0;Mucus glandular cells: 371.0;Serous glandular cells: 205.1" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 124.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2374.2" "Lineage enriched" "Detected in many" 1592 "granulocytes: 2374.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 60.5;breast cancer: 64.8;ovarian cancer: 61.4" "Lung - Neutrophil_1, Pancreas - Ductal cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 4000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 39: Non-specific - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" "prognostic favorable (1.90e-4)" "unprognostic (1.17e-1)" "unprognostic (5.89e-2)" "unprognostic (3.61e-3)" "unprognostic (2.49e-2)" "unprognostic (5.28e-3)" "unprognostic (4.52e-3)" "unprognostic (3.11e-3)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (9.07e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.56e-8)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "dendritic cells: 23.3;Hofbauer cells: 48.3;Kupffer cells: 45.1;Macrophages: 71.6;Microglial cells: 58.4;Proximal tubular cells: 81.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Group enriched" "Detected in some" 14 "Leukemia: 13.1;lymphoma: 18.0;Rhabdoid: 6.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA050528, HPA063577" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm Cytosol "CAB032260: AB_2202845, HPA050528: , HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 115.5;Mucus glandular cells: 96.9;Muller glia cells: 47.1;Salivary duct cells: 78.6" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 46.3;Microglial cells: 14.6;Serous glandular cells: 10.9;T-cells: 66.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 19 "Leukemia: 3.6;lymphoma: 3.1;Myeloma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Metabolic proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 13.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 365.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 36.9" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: AB_1858005, HPA013903: AB_1858004" "unprognostic (9.14e-2)" "unprognostic (5.79e-2)" "unprognostic (1.44e-1)" "unprognostic (6.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.74e-2)" "unprognostic (1.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.38e-3)" "unprognostic (1.82e-1)" "unprognostic (8.13e-2)" "unprognostic (6.04e-2)" "unprognostic (1.05e-1)" TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 126.1;Endothelial cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in many" 5 "Leukemia: 12.2;ovarian cancer: 22.4;Sarcoma: 24.1;thyroid cancer: 28.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 843.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "CAB010822: , HPA001636: AB_1080762, HPA001637: AB_1080760" "unprognostic (2.11e-2)" "unprognostic (6.83e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (6.71e-3)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.86e-3)" "unprognostic (3.54e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.85e-3)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 55.3;Macrophages: 25.3;monocytes: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 26.1;granulocytes: 32.2;Hofbauer cells: 54.0;Langerhans cells: 61.5;Macrophages: 43.7;Microglial cells: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Group enriched" "Detected in many" 5 "Leukemia: 10.0;lymphoma: 9.4;Myeloma: 3.4" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Macrophages, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 69: Macrophages - Innate immune response" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" TMEM132D "KIAA1944, MOLT, PPP1R153" ENSG00000151952 "Transmembrane protein 132D" Q14C87 12 129071725-129904025 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 5.5" "Group enriched" "Detected in some" 60 "Excitatory neurons: 442.4;Inhibitory neurons: 509.3;Oligodendrocyte precursor cells: 548.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010739 Approved NA NA 110000 "Cluster 10: Brain - Neuronal signaling" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 32: Neurons - Synaptic function" "HPA010739: AB_2204753" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (5.39e-1)" "unprognostic (1.47e-2)" "unprognostic (2.89e-1)" "unprognostic (3.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.31e-4)" TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 67.8;pituitary gland: 18.3;retina: 28.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.6;Cone photoreceptor cells: 25.8;Excitatory neurons: 26.1;Horizontal cells: 78.8;Inhibitory neurons: 53.1;Rod photoreceptor cells: 28.8" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 6.8;neutrophil: 14.2" "Lineage enriched" "Detected in many" 11 "granulocytes: 14.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 22.6" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" TMEM158 "p40BBp, RIS1" ENSG00000249992 "Transmembrane protein 158" Q8WZ71 3 45224466-45226287 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;endometrium 1: 69.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.3;Breast myoepithelial cells: 26.2;Endometrial stromal cells: 61.6;Muller glia cells: 76.6" "Cancer enhanced" "Detected in many" "glioma: 38.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 56.3" "Pancreas - Ductal cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "basal ganglia: 95.5" "Low region specificity" "Detected in all" HPA074974 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 68: Muller glia cells - Visual perception" "HPA074974: AB_2732274" "unprognostic (3.84e-1)" "unprognostic (9.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.77e-2)" "unprognostic (5.73e-2)" "unprognostic (3.31e-2)" "unprognostic (4.67e-3)" "unprognostic (6.23e-2)" "unprognostic (6.41e-2)" "unprognostic (1.84e-3)" "prognostic favorable (6.43e-5)" "prognostic unfavorable (5.42e-9)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (2.86e-2)" "unprognostic (4.49e-3)" TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 60.9;Endothelial cells: 87.8;granulocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" TMEM61 ENSG00000143001 "Transmembrane protein 61" Q8N0U2 1 54980628-54992288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 23.7;parathyroid gland: 13.6;pituitary gland: 47.6;salivary gland: 19.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.8;Enteroendocrine cells: 26.4;Intestinal goblet cells: 56.7;Ionocytes: 43.0;Mucus glandular cells: 20.7;Salivary duct cells: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.4;pancreatic cancer: 3.4" "Adipose subcutaneous - Smooth muscle cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA030614 Uncertain NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA030614: AB_10603216" "unprognostic (7.62e-2)" "unprognostic (1.67e-3)" "prognostic favorable (1.07e-4)" "unprognostic (1.00e-1)" "unprognostic (6.63e-4)" "unprognostic (6.15e-2)" "unprognostic (2.67e-3)" "unprognostic (1.49e-1)" "unprognostic (3.05e-1)" "unprognostic (4.46e-2)" "unprognostic (1.91e-2)" "unprognostic (7.24e-2)" "prognostic favorable (1.78e-7)" "unprognostic (8.47e-2)" "unprognostic (2.20e-2)" "unprognostic (4.01e-2)" "unprognostic (4.62e-3)" TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 14.3;Hofbauer cells: 36.3;Late spermatids: 11.7;Theca cells: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Breast - Breast glandular cells, Lung - Macrophages, Pancreas - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 65: Breast cancer - Unknown function" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 128.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 73.0;Late spermatids: 161.2" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Group enriched" "Detected in some" 4 "basal ganglia: 4.4;thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.5;lymphoma: 4.0" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.3" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 51: Late spermatids - Spermatogenesis" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883312 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 519.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 1484.6;granulocytes: 1660.0;monocytes: 885.5;T-cells: 735.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 95.2" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 74.3;Kupffer cells: 45.0;Macrophages: 38.3;monocytes: 43.5;NK-cells: 24.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 27.0;lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 15 "Plasma cells: 468.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cancer enriched" "Detected in some" 12 "Myeloma: 633.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 17 "NK-cells: 443.4;T-cells: 435.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 98.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 150.2;NK-cells: 264.0;T-cells: 515.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cancer enriched" "Detected in single" 15 "Leukemia: 12.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in some" 7 "Hofbauer cells: 916.9" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;Leukemia: 2.4;testis cancer: 1.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Sebaceous gland cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 69: Macrophages - Innate immune response" Vesicles "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 4 "NK-cells: 84.0;T-cells: 110.9" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Group enriched" "Detected in some" 23 "Leukemia: 42.6;prostate cancer: 13.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - Prostate glandular cells, Skin - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" TRIM10 "HERF1, RFB30, RNF9" ENSG00000204613 "Tripartite motif containing 10" Q9UDY6 6 30151943-30161211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.8;kidney: 2.0;liver: 2.9" "Cell type enriched" "Detected in some" 15 "Erythroid cells: 74.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.1" "Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "hippocampal formation: 3.4" HPA043325 Uncertain NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "HPA043325: AB_2678428" "unprognostic (2.98e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (2.13e-1)" "unprognostic (2.98e-1)" "unprognostic (9.53e-3)" "unprognostic (6.32e-2)" "unprognostic (2.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.74e-3)" "unprognostic (1.46e-2)" "unprognostic (4.37e-2)" "unprognostic (1.22e-2)" TRIM46 "FLJ23229, TRIFIC" ENSG00000163462 "Tripartite motif containing 46" Q7Z4K8 1 155173787-155184971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 12.9;Horizontal cells: 10.9;Inhibitory neurons: 9.5;Late spermatids: 9.6;Oligodendrocytes: 9.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.8" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055583 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 30: Breast - Lactation" "HPA055583: AB_2732599" "unprognostic (1.06e-1)" "unprognostic (5.07e-2)" "unprognostic (2.86e-2)" "prognostic unfavorable (2.61e-7)" "unprognostic (1.75e-1)" "unprognostic (7.26e-2)" "unprognostic (1.59e-2)" "unprognostic (4.65e-2)" "unprognostic (4.09e-1)" "unprognostic (2.88e-2)" "unprognostic (2.18e-3)" "unprognostic (1.24e-1)" "unprognostic (2.29e-12)" "unprognostic (8.58e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.72e-2)" TTC9 "KIAA0227, TTC9A" ENSG00000133985 "Tetratricopeptide repeat domain 9" Q92623 14 70641916-70675366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.1" "Cell type enhanced" "Detected in many" "Ionocytes: 33.3;Respiratory ciliated cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079473 Approved "Nuclear bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies" "HPA079473: " "unprognostic (2.37e-2)" "unprognostic (6.01e-2)" "unprognostic (9.29e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.81e-2)" "unprognostic (2.38e-2)" "unprognostic (2.53e-2)" "unprognostic (7.12e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.18e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.10e-8)" "unprognostic (1.22e-2)" "unprognostic (1.01e-1)" "unprognostic (3.16e-2)" "unprognostic (9.38e-2)" TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 97.6;Fibroblasts: 68.1;granulocytes: 44.2;Langerhans cells: 30.1;Leydig cells: 46.8;Peritubular cells: 40.6;Thymic epithelial cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cancer enhanced" "Detected in many" "Sarcoma: 11.5" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 5212.6;Kupffer cells: 2893.4;Langerhans cells: 2460.5;Macrophages: 2602.8;monocytes: 3238.5;NK-cells: 1335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 53 "Leukemia: 105.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enriched" "Detected in some" 5 "T-cells: 21.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 57 "Leukemia: 8.9;lymphoma: 2.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" UBD FAT10 ENSG00000213886 "Ubiquitin D" O15205 6 29555515-29559732 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 151.3" "Group enriched" "Detected in many" 9 "Ductal cells: 421.1;Exocrine glandular cells: 613.6;Pancreatic endocrine cells: 168.3" "Cancer enhanced" "Detected in all" "liver cancer: 75.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 21.6;thyroid cancer: 43.3" "Breast - T-cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043710 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "Nucleoli fibrillar center" "HPA043710: AB_2756303" "unprognostic (2.99e-3)" "unprognostic (4.16e-2)" "unprognostic (6.37e-2)" "unprognostic (2.61e-2)" "unprognostic (3.93e-2)" "unprognostic (3.53e-3)" "unprognostic (1.60e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-2)" "prognostic favorable (7.35e-4)" "unprognostic (1.28e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (4.04e-2)" "unprognostic (6.02e-2)" "unprognostic (8.40e-2)" "unprognostic (1.21e-2)" UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.2;Cardiomyocytes: 29.9;Cone photoreceptor cells: 27.6;Excitatory neurons: 47.1;Granulosa cells: 45.4;Horizontal cells: 26.9;Inhibitory neurons: 34.4;Rod photoreceptor cells: 58.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 16.3" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pancreas - Alpha cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 51: Myeloma - Humoral immune response" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 692.7;pituitary gland: 285.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 131.9;Distal tubular cells: 230.1;Excitatory neurons: 145.0;Horizontal cells: 180.7;Inhibitory neurons: 115.6;Pancreatic endocrine cells: 123.7;Spermatogonia: 97.5" "Cancer enhanced" "Detected in all" "glioma: 129.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 500000 "Cluster 43: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.93e-4)" VAT1L KIAA1576 ENSG00000171724 "Vesicle amine transport 1 like" Q9HCJ6 16 77788564-77980107 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "adrenal gland: 70.1;brain: 186.9;choroid plexus: 232.4;retina: 188.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 20.3;Horizontal cells: 122.4;Inhibitory neurons: 30.5;Muller glia cells: 104.4;Oligodendrocyte precursor cells: 42.8" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 14.6;Neuroblastoma: 16.7;testis cancer: 14.1" "Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Pancreas - Beta cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044061, CAB046032, HPA061138" Enhanced Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 68: Muller glia cells - Visual perception" Cytosol "CAB046032: AB_11126308, HPA044061: AB_10959610, HPA061138: " "unprognostic (1.49e-2)" "unprognostic (8.74e-3)" "unprognostic (8.80e-3)" "unprognostic (3.39e-2)" "unprognostic (3.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (8.57e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.01e-6)" "unprognostic (2.50e-2)" "unprognostic (6.53e-2)" "unprognostic (1.19e-1)" "unprognostic (5.96e-2)" VENTX "HPX42B, VENTX2" ENSG00000151650 "VENT homeobox" O95231 10 133237855-133241928 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Kupffer cells: 7.8;Langerhans cells: 10.8;Macrophages: 9.1;monocytes: 11.5" "Cancer enriched" "Detected in some" 15 "testis cancer: 30.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;granulocytes: 1.9;monocytes: 3.2" "Cancer enhanced" "Detected in some" "Leukemia: 1.8;testis cancer: 1.3" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" HPA050955 Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoli fibrillar center" "HPA050955: AB_2681288" "unprognostic (9.41e-2)" "unprognostic (8.89e-2)" "unprognostic (2.34e-1)" "unprognostic (4.26e-1)" "unprognostic (3.22e-2)" "unprognostic (2.01e-1)" "unprognostic (2.54e-1)" "unprognostic (9.62e-3)" "unprognostic (2.22e-1)" "unprognostic (3.00e-3)" "unprognostic (3.70e-4)" "unprognostic (4.22e-1)" "unprognostic (2.51e-3)" "unprognostic (3.43e-2)" "unprognostic (3.48e-1)" "unprognostic (7.54e-2)" "unprognostic (3.14e-1)" VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.3;salivary gland: 3.3;thyroid gland: 3.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.8;Excitatory neurons: 11.6;Granulosa cells: 5.4;Inhibitory neurons: 11.2;Serous glandular cells: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.4" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA026619: AB_2671920, HPA036044: AB_2674916, HPA036045: " "unprognostic (6.39e-2)" "unprognostic (1.65e-3)" "unprognostic (5.36e-3)" "unprognostic (1.78e-4)" "unprognostic (1.39e-2)" "unprognostic (4.19e-3)" "unprognostic (2.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (6.25e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enhanced" "Detected in some" "Distal tubular cells: 174.1;Intestinal goblet cells: 75.0;Prostatic glandular cells: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 23.0;Basal respiratory cells: 43.1;Breast glandular cells: 24.4;Breast myoepithelial cells: 26.6;Endometrial stromal cells: 77.4;Suprabasal keratinocytes: 53.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.1" "Lung - Alveolar cells type 2, Pancreas - Alpha cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 52: Endometrial stromal cells - ECM organization" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" ZCCHC18 "PNMA7B, SIZN2" ENSG00000166707 "Zinc finger CCHC-type containing 18" P0CG32 X 104112131-104115842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;ovary: 4.2" "Cell type enhanced" "Detected in some" "B-cells: 3.8;Cardiomyocytes: 11.4;Horizontal cells: 5.1;Muller glia cells: 3.8;NK-cells: 5.5;Oligodendrocyte precursor cells: 6.3" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5" "Pancreas - Alpha cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA034940, HPA078516" Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 77: Cardiomyocytes - Muscle contraction" Vesicles "HPA034940: AB_10671098, HPA078516: " "unprognostic (7.20e-2)" "unprognostic (7.71e-4)" "unprognostic (8.29e-2)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-3)" "unprognostic (2.20e-2)" "unprognostic (3.22e-2)" "unprognostic (7.59e-2)" "unprognostic (3.34e-1)" "unprognostic (4.44e-6)" "unprognostic (4.05e-2)" "unprognostic (1.02e-6)" "unprognostic (3.82e-2)" "unprognostic (4.02e-1)" "unprognostic (3.91e-2)" "unprognostic (4.14e-3)" ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 347.3;Bipolar cells: 81.2;Oligodendrocyte precursor cells: 224.3;Oligodendrocytes: 210.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" ZFPM2 "FOG2, hFOG-2, ZC2HC11B, ZNF89B" ENSG00000169946 "Zinc finger protein, FOG family member 2" Q8WW38 8 104590733-105804539 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Gonadal differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.2;ovary: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 517.2;Inhibitory neurons: 156.3;Microglial cells: 148.7;Oligodendrocyte precursor cells: 660.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 64.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.1" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 39.4" HPA004094 Approved Supported Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA004094: AB_1859058" "unprognostic (4.48e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-3)" "unprognostic (1.36e-2)" "unprognostic (3.51e-1)" "unprognostic (1.53e-1)" "unprognostic (8.37e-2)" "unprognostic (8.35e-3)" "unprognostic (1.97e-2)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-6)" "unprognostic (4.10e-3)" "unprognostic (5.41e-2)" "unprognostic (1.63e-4)" "unprognostic (2.61e-2)" ZFR2 KIAA1086 ENSG00000105278 "Zinc finger RNA binding protein 2" Q9UPR6 19 3804024-3869038 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.0;pituitary gland: 26.1;retina: 10.9;testis: 13.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 36.3;Cone photoreceptor cells: 37.9;Early spermatids: 22.9;Excitatory neurons: 38.7;Horizontal cells: 34.6;Inhibitory neurons: 41.6;Rod photoreceptor cells: 37.2;Spermatocytes: 26.6" "Cancer enhanced" "Detected in some" "cervical cancer: 2.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043275, HPA055678" Uncertain Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "HPA043275: , HPA055678: AB_2682883" "unprognostic (1.74e-3)" "unprognostic (2.32e-3)" "unprognostic (4.05e-3)" "unprognostic (1.51e-2)" "unprognostic (6.60e-3)" "unprognostic (5.47e-4)" "unprognostic (9.12e-2)" "unprognostic (3.87e-2)" "unprognostic (1.18e-2)" "unprognostic (4.92e-2)" "unprognostic (1.97e-3)" "unprognostic (4.29e-2)" "unprognostic (3.58e-1)" "unprognostic (3.58e-1)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (2.18e-2)" ZNF683 "Hobit, MGC33414" ENSG00000176083 "Zinc finger protein 683" Q8IZ20 1 26361634-26374522 "Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 81.9" "Group enriched" "Detected in some" 14 "Early spermatids: 346.9;Late spermatids: 550.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 172.4;memory CD8 T-cell: 113.1" "Lineage enriched" "Detected in many" 15 "T-cells: 172.4" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Pancreas - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" HPA023865 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 24: Spermatids - Unknown function" "HPA023865: AB_2671333" "unprognostic (3.95e-3)" "unprognostic (5.58e-3)" "unprognostic (5.83e-2)" "prognostic favorable (2.90e-5)" "unprognostic (9.17e-2)" "unprognostic (8.98e-4)" "unprognostic (7.90e-2)" "unprognostic (5.05e-3)" "unprognostic (5.81e-3)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.30e-2)" "unprognostic (3.54e-8)" "unprognostic (5.90e-3)" "unprognostic (1.63e-1)" "unprognostic (1.14e-2)" "prognostic favorable (3.45e-5)"