Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1264.3;Cardiomyocytes: 398.0;Endothelial cells: 864.5;Hepatocytes: 661.1;Kupffer cells: 338.8;Microglial cells: 345.7;Smooth muscle cells: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;liver cancer: 139.1;skin cancer: 83.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: Liver cancer - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 102.0;Microglial cells: 555.5;Proximal enterocytes: 250.9" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 24.8;liver cancer: 18.1" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Plasma membrane" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" ABHD11 "PP1226, WBSCR21" ENSG00000106077 "Abhydrolase domain containing 11" Q8NFV4 7 73736094-73738867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024042, HPA049641" Approved Supported Mitochondria NA NA 31000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA024042: AB_1844445, HPA049641: AB_2680838" "unprognostic (4.74e-2)" "unprognostic (8.62e-3)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-3)" "unprognostic (1.91e-2)" "unprognostic (9.32e-2)" "unprognostic (7.79e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.66e-7)" "unprognostic (3.61e-3)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (7.29e-2)" ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 180.4;Cardiomyocytes: 69.9;Hepatocytes: 95.2;Oligodendrocyte precursor cells: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.2" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" AC135068.1 ENSG00000278263 "Novel protein, identical to IGHV4-4" 15 21742364-21742799 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 52.2;lymphoid tissue: 57.9;urinary bladder: 97.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "memory B-cell: 24.0;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 45 "B-cells: 24.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (1.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "prognostic favorable (2.52e-4)" "unprognostic (1.05e-1)" "unprognostic (9.75e-3)" "unprognostic (1.80e-2)" "unprognostic (5.51e-6)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-1)" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 325.3;Hepatocytes: 791.9;Proximal enterocytes: 428.9;Proximal tubular cells: 528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 10 "Late spermatids: 3052.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 84 "Leukemia: 30.1;lymphoma: 34.7;Myeloma: 16.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 51: Late spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 9 "Adipocytes: 579.9;Endothelial cells: 700.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.7;Brain cancer: 2.0;Leukemia: 1.5;Neuroblastoma: 2.1;skin cancer: 2.7" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 176.4;Proximal tubular cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 60: Proximal tubular cells - Absorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.4;Hepatocytes: 29.0;Proximal tubular cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 78.1;Hofbauer cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 69.9" "Lineage enriched" "Detected in all" 5 "monocytes: 69.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Enzymes" "Cluster 69: Macrophages - Innate immune response" "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037193, HPA047443" Approved Approved Microtubules NA NA 560000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 74: Pancreatic cells - Mixed function" Microtubules "CAB037193: AB_258253, HPA047443: AB_2680049" "unprognostic (9.64e-3)" "unprognostic (1.92e-2)" "unprognostic (8.34e-2)" "unprognostic (4.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.77e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (4.13e-1)" ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.1;Fibroblasts: 37.1;Kupffer cells: 67.8;Macrophages: 23.2;Thymic epithelial cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 145.4;Endometrial stromal cells: 37.2;Extravillous trophoblasts: 45.0;Skeletal myocytes: 51.5;Syncytiotrophoblasts: 94.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bladder cancer: 38.4" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 348.1;Rod photoreceptor cells: 620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1739.4;Excitatory neurons: 3790.8;Inhibitory neurons: 2675.1;Oligodendrocyte precursor cells: 1950.0;Oligodendrocytes: 1142.7" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.0" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 38.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Extravillous trophoblasts: 17.4;Squamous epithelial cells: 16.6;Suprabasal keratinocytes: 32.4;Syncytiotrophoblasts: 9.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.3;head and neck cancer: 14.6" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.4;Exocrine glandular cells: 161.1;NK-cells: 183.6;Syncytiotrophoblasts: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.9;lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "B-cells: 6.2;dendritic cells: 30.5;Microglial cells: 10.9;NK-cells: 27.5;Plasma cells: 16.9;T-cells: 6.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 125.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 9.6;lymphoma: 6.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 890.6;Inhibitory neurons: 631.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 565.9;Excitatory neurons: 686.2;Inhibitory neurons: 720.0;Oligodendrocyte precursor cells: 1245.7;Oligodendrocytes: 559.0" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2138.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 23.2" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.0;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 135 "Bone cancer: 19.1" "Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 53: Connective tissue cells - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 114.1;Proximal tubular cells: 124.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.4;intermediate monocyte: 16.7;memory B-cell: 5.4;myeloid DC: 7.6;non-classical monocyte: 11.0;plasmacytoid DC: 5.1" "Group enriched" "Detected in all" 5 "B-cells: 5.4;dendritic cells: 7.6;monocytes: 16.7" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" AKNA KIAA1968 ENSG00000106948 "AT-hook transcription factor" Q7Z591 9 114334156-114394405 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.6" "Cell type enhanced" "Detected in many" "dendritic cells: 140.8;monocytes: 113.9;NK-cells: 363.3;Rod photoreceptor cells: 137.5;T-cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Leukemia: 57.2;lymphoma: 67.9;Myeloma: 43.3" "Colon - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052367, HPA063993" Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Centrosome, Cytosol" "HPA052367: AB_2681801, HPA063993: AB_2685169" "unprognostic (5.19e-3)" "prognostic favorable (1.22e-4)" "unprognostic (5.38e-3)" "prognostic favorable (2.14e-5)" "unprognostic (3.12e-1)" "prognostic favorable (1.25e-4)" "unprognostic (1.88e-1)" "unprognostic (3.28e-2)" "unprognostic (4.13e-2)" "unprognostic (6.62e-2)" "unprognostic (5.85e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.19e-2)" "unprognostic (6.61e-3)" "unprognostic (2.93e-1)" "prognostic favorable (2.29e-4)" AKTIP "FLJ13258, FTS" ENSG00000166971 "AKT interacting protein" Q9H8T0 16 53491040-53504411 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 361.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041794, HPA046300" Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 54: Non-specific - Microtubule organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 36: Spermatids - Spermatogenesis" "HPA041794: AB_2677677, HPA046300: AB_2679619" "unprognostic (2.08e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-2)" "unprognostic (5.44e-2)" "unprognostic (2.62e-2)" "unprognostic (9.90e-2)" "unprognostic (1.72e-2)" "unprognostic (3.41e-3)" "unprognostic (2.45e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "prognostic favorable (1.18e-14)" "unprognostic (2.39e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-1)" "unprognostic (1.31e-1)" AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 83.5;kidney: 39.8;liver: 37.8" "Group enriched" "Detected in many" 4 "Distal enterocytes: 560.8;Proximal enterocytes: 1919.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.3;Gastric cancer: 5.1;liver cancer: 6.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.2;Late spermatids: 75.6;Oligodendrocyte precursor cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 38.5;Endothelial cells: 26.9;Fibroblasts: 77.2;Oligodendrocyte precursor cells: 33.7;Skeletal myocytes: 35.6;Smooth muscle cells: 40.6;Thymic epithelial cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 25.1" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 203.1;Leydig cells: 61.9;Peritubular cells: 78.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.7;Hofbauer cells: 195.2;Inhibitory neurons: 209.1;Oligodendrocytes: 246.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Uncertain Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 183.4;Microglial cells: 380.4;NK-cells: 145.7;Oligodendrocyte precursor cells: 167.5;Oligodendrocytes: 188.3;T-cells: 135.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 31.6" "Adipose visceral - T-cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Group enriched" "Detected in some" 4 "Late spermatids: 289.5;Microglial cells: 139.6;Rod photoreceptor cells: 186.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 332.5;Peritubular cells: 215.1;Syncytiotrophoblasts: 232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.3;Basal respiratory cells: 45.2;Excitatory neurons: 47.1;Inhibitory neurons: 40.0;Oligodendrocyte precursor cells: 48.6;Oligodendrocytes: 45.5;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 79.3;Thymic epithelial cells: 143.4" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "head and neck cancer: 250.6" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 60.5;Kupffer cells: 93.5;Macrophages: 75.0;Microglial cells: 227.1;monocytes: 89.5;NK-cells: 101.0;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "colorectal cancer: 4.1;Leukemia: 6.1;lymphoma: 3.4" "Breast - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Stomach - Macrophages, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "Endoplasmic reticulum" "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 91.1;dendritic cells: 126.6;Kupffer cells: 121.2;Macrophages: 121.4;Microglial cells: 371.2;monocytes: 108.2;NK-cells: 121.7;T-cells: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Kidney cancer: 37.1;Leukemia: 69.8;lymphoma: 80.6;Myeloma: 23.1" "Breast - Adipocytes (Breast), Colon - Macrophages, Heart muscle - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 3.9;Cytotrophoblasts: 6.8;Hofbauer cells: 4.2;NK-cells: 8.3;Sertoli cells: 5.5;T-cells: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Group enriched" "Detected in some" 5 "Leukemia: 6.6;lymphoma: 7.8;Myeloma: 5.3" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Sertoli cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 109.5;Proximal enterocytes: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925, HPA079223" Approved Approved Vesicles,Cytosol NA NA 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 50: Enterocytes - Absorption" Vesicles Cytosol "HPA039688: AB_2676626, HPA043925: AB_2678733, HPA079223: " "unprognostic (3.46e-1)" "unprognostic (4.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-2)" "unprognostic (6.66e-3)" "unprognostic (8.43e-2)" "unprognostic (5.50e-2)" "unprognostic (5.71e-3)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "prognostic favorable (7.65e-4)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (9.32e-2)" ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Astrocytes: 239.1;Excitatory neurons: 262.8;Oligodendrocyte precursor cells: 322.5;Oligodendrocytes: 781.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" ARHGAP25 KIAA0053 ENSG00000163219 "Rho GTPase activating protein 25" P42331 2 68679601-68826833 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.8" "Cell type enhanced" "Detected in many" "B-cells: 88.5;granulocytes: 36.3;Hofbauer cells: 42.7;Microglial cells: 85.7;NK-cells: 71.4;T-cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 657.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 25.0;lymphoma: 39.2;Myeloma: 13.6" "Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035346, HPA061395" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Nucleoplasm, Vesicles" "HPA035346: AB_10601116, HPA061395: AB_2684501" "unprognostic (1.13e-3)" "prognostic favorable (7.72e-4)" "unprognostic (2.45e-2)" "unprognostic (4.44e-3)" "unprognostic (8.07e-2)" "unprognostic (1.36e-2)" "unprognostic (1.13e-1)" "unprognostic (6.16e-3)" "unprognostic (2.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.00e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.10e-1)" "unprognostic (4.26e-2)" "unprognostic (3.61e-1)" "unprognostic (4.49e-2)" ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 414.1;Endothelial cells: 304.0;Microglial cells: 203.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 76.1;Hofbauer cells: 72.5;Kupffer cells: 83.0;Macrophages: 77.6;monocytes: 193.2;NK-cells: 196.5;T-cells: 99.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 31 "Leukemia: 74.1;lymphoma: 100.9;Myeloma: 118.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "B-cells: 74.4;Kupffer cells: 76.7;monocytes: 87.2;NK-cells: 81.1;Syncytiotrophoblasts: 74.6;T-cells: 93.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 92.8;lymphoma: 78.9;Myeloma: 97.0" "Colon - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 80.3;Early spermatids: 119.5;Hofbauer cells: 50.7;NK-cells: 176.8;Spermatocytes: 78.1;T-cells: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 35.3;lymphoma: 19.9;Myeloma: 14.7" "Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in many" "NK-cells: 181.7;T-cells: 156.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 82.2;granulocytes: 131.6;Granulosa cells: 117.1;Microglial cells: 75.7" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 94.2;lymphoma: 34.9" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003578, HPA071036" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 62: Granulocytes - Innate immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane, Cytosol" "HPA003578: AB_1078203, HPA071036: " "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 15.4;Hofbauer cells: 33.4;Kupffer cells: 19.2;Macrophages: 21.5;monocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Leukemia: 12.2;lymphoma: 8.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 19: Macrophages - Innate immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1233.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 46.1;Gastric cancer: 16.7" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 54: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 209.9;Alveolar cells type 2: 207.5;Glandular and luminal cells: 152.7;Oligodendrocytes: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 46: Non-specific - Unknown function" "Cluster 41: Alveolar cells - Lung function" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Approved NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 48: Non-specific - RNA binding" "Cluster 19: Macrophages - Innate immune response" "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 134.0;Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 37: Neurons - Neuronal signaling" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 149.0;Langerhans cells: 171.5;Squamous epithelial cells: 170.0;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Early spermatids" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" BAIAP2L1 IRTKS ENSG00000006453 "BAR/IMD domain containing adaptor protein 2 like 1" Q9UHR4 7 98291650-98401090 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 58.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 90.6;Gastric mucus-secreting cells: 96.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" Cytosol "HPA019484: AB_1845265, HPA021257: AB_1845266, HPA023874: AB_1845267, HPA029503: AB_10602330" "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.00e-1)" "unprognostic (2.95e-1)" "unprognostic (2.80e-2)" "unprognostic (8.31e-3)" "unprognostic (4.56e-2)" "unprognostic (1.34e-2)" "unprognostic (9.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.7;lymphoid tissue: 30.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 105.6;Breast myoepithelial cells: 80.1;granulocytes: 152.2;Hofbauer cells: 59.4;NK-cells: 63.8;T-cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.3" "Cancer enhanced" "Detected in many" "lymphoma: 81.9" "Adipose visceral - Macrophages, Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Urothelial cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA059588: AB_2684074, HPA064962: AB_2685392" "unprognostic (3.33e-3)" "unprognostic (4.87e-3)" "prognostic unfavorable (8.30e-4)" "prognostic favorable (5.35e-6)" "unprognostic (3.02e-2)" "prognostic favorable (7.91e-5)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (6.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (3.74e-9)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "prognostic favorable (4.30e-4)" BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in many" "Adipocytes: 363.1;Basal respiratory cells: 438.9;Collecting duct cells: 494.2;Cytotrophoblasts: 694.8;Syncytiotrophoblasts: 411.6" "Cancer enhanced" "Detected in all" "ovarian cancer: 493.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 18000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 28: Cytotrophoblasts - Unknown function" "Nucleoli fibrillar center" "HPA005654: AB_2667378" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (2.61e-3)" "unprognostic (1.41e-1)" "prognostic favorable (5.94e-6)" "unprognostic (1.83e-2)" "unprognostic (5.74e-2)" "unprognostic (2.14e-2)" "unprognostic (9.97e-3)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.8;Basal squamous epithelial cells: 90.5;Inhibitory neurons: 103.1;NK-cells: 137.8;Suprabasal keratinocytes: 77.0;T-cells: 295.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "Bone cancer: 18.1;Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 46: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" BCL7B ENSG00000106635 "BAF chromatin remodeling complex subunit BCL7B" Q9BQE9 7 73536356-73557690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Wnt signaling pathway" "Allergen, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049943, HPA058069" Approved Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: Non-specific - Transcription" "Cluster 11: Non-specific - Transcription" Nucleoplasm "HPA049943: AB_2680963, HPA058069: AB_2683594" "unprognostic (2.79e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (3.54e-3)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" "unprognostic (4.84e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (5.37e-2)" "unprognostic (9.43e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.41e-2)" "unprognostic (1.32e-1)" BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.7;Hepatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 28.8;Cone photoreceptor cells: 31.0;Distal tubular cells: 31.1;Proximal tubular cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.9" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 466.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" HPA047390 Approved Nucleoli NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA047390: AB_2680025" "unprognostic (1.05e-2)" "unprognostic (7.91e-3)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.08e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (3.51e-1)" "unprognostic (4.45e-1)" "unprognostic (1.91e-3)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.96e-2)" "unprognostic (7.62e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.28e-5)" BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 274.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol NA NA 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 63: Non-specific - Unknown function" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450" "unprognostic (2.47e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.16e-3)" "unprognostic (6.45e-3)" "unprognostic (5.01e-2)" "unprognostic (1.63e-2)" "prognostic favorable (8.65e-4)" "unprognostic (1.42e-1)" "unprognostic (1.75e-2)" "unprognostic (2.93e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (5.63e-3)" "unprognostic (3.18e-1)" "unprognostic (2.13e-3)" "unprognostic (4.56e-2)" BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Endothelial cells: 34.0;Smooth muscle cells: 8.1" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Group enriched" "Detected in some" 6 "lung cancer: 5.3;prostate cancer: 1.6" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 56: Neurons - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Leydig cells: 91.9;Microglial cells: 224.4;Peritubular cells: 69.0;Thymic epithelial cells: 79.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 72.3;Plasma cells: 33.1;T-cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.1;Kupffer cells: 21.8;Langerhans cells: 19.5;monocytes: 54.7;NK-cells: 37.9;T-cells: 15.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 9 "Leukemia: 24.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" C11orf95 MGC3032 ENSG00000188070 "Chromosome 11 open reading frame 95" C9JLR9 11 63759892-63768775 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045002 Approved "Intermediate filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Intermediate filaments" "HPA045002: AB_2679179" "unprognostic (4.23e-3)" "unprognostic (7.24e-3)" "unprognostic (6.47e-2)" "unprognostic (9.01e-3)" "unprognostic (7.54e-2)" "unprognostic (3.89e-1)" "unprognostic (8.94e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" "unprognostic (8.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.52e-3)" "unprognostic (1.85e-2)" "unprognostic (6.60e-2)" "unprognostic (5.68e-2)" "unprognostic (1.31e-3)" C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.8;Alveolar cells type 2: 40.2;Basal prostatic cells: 57.3;Bipolar cells: 48.3;Endometrial ciliated cells: 61.7;Horizontal cells: 43.6" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 63.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 70: Basal prostatic cells - Lipid metabolism" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" C15orf62 LOC643338 ENSG00000188277 "Chromosome 15 open reading frame 62" A8K5M9 15 40769980-40772449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.0;skin 1: 17.1" "Cell type enhanced" "Detected in some" "Club cells: 9.1;Glandular and luminal cells: 6.2;Ionocytes: 6.0;Mucus glandular cells: 7.8;Squamous epithelial cells: 5.6;Suprabasal keratinocytes: 5.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Low region specificity" "Detected in all" HPA044636 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA044636: AB_10794052" "unprognostic (9.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.52e-1)" "unprognostic (2.83e-2)" "unprognostic (5.56e-2)" "unprognostic (2.24e-2)" "unprognostic (5.37e-3)" "unprognostic (7.68e-3)" "unprognostic (1.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (1.60e-1)" "unprognostic (3.40e-1)" C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 361.1;Kupffer cells: 668.2;Langerhans cells: 256.1;Macrophages: 441.8;monocytes: 553.5;NK-cells: 193.9;Schwann cells: 450.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Leukemia: 20.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.4;Squamous epithelial cells: 27.5;Suprabasal keratinocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" C20orf194 DKFZp434N061 ENSG00000088854 "Chromosome 20 open reading frame 194" Q5TEA3 20 3249306-3407669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 219.8;Excitatory neurons: 202.6;Inhibitory neurons: 159.4;Oligodendrocyte precursor cells: 130.0;Oligodendrocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052103, HPA067418" Approved Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 38: Neurons - Neuronal signaling" "Nucleoli fibrillar center, Cytosol" "HPA052103: AB_2681727, HPA067418: AB_2685835" "unprognostic (9.77e-2)" "unprognostic (8.39e-2)" "unprognostic (5.03e-3)" "unprognostic (1.83e-1)" "unprognostic (1.18e-1)" "unprognostic (4.26e-2)" "unprognostic (1.66e-2)" "unprognostic (7.64e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.97e-1)" "prognostic favorable (7.68e-4)" "unprognostic (9.58e-3)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (7.52e-2)" C2orf15 MGC29762 ENSG00000273045 "Chromosome 2 open reading frame 15" Q8WU43 2 99141707-99151669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 12.4;Proximal tubular cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (2.61e-2)" "unprognostic (7.88e-2)" "unprognostic (4.22e-2)" "unprognostic (4.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.99e-2)" "unprognostic (5.37e-2)" "unprognostic (9.05e-3)" "unprognostic (1.62e-2)" "prognostic favorable (4.95e-4)" "unprognostic (2.54e-3)" "unprognostic (1.04e-1)" "prognostic favorable (1.23e-4)" "unprognostic (2.06e-1)" "unprognostic (4.22e-4)" "unprognostic (5.08e-1)" "unprognostic (2.97e-2)" CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Oligodendrocyte precursor cells: 124.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cancer enhanced" "Detected in many" "Leukemia: 6.0;skin cancer: 8.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 323.0;Extravillous trophoblasts: 616.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006018, HPA071040" Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA006018: AB_1845934, HPA071040: " "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043830 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: Liver cancer - Metabolism" "Cluster 30: Breast - Lactation" "HPA043830: AB_10795879" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 13 "Gastric mucus-secreting cells: 825.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 29.2;colorectal cancer: 29.2;Gastric cancer: 36.3" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 58: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 85.7;skin 1: 102.4" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 134.7;Basal squamous epithelial cells: 96.5;Squamous epithelial cells: 112.6;Suprabasal keratinocytes: 230.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.3;urothelial cancer: 21.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Cancer enhanced" "Detected in some" "Esophageal cancer: 18.0;head and neck cancer: 17.6" "Prostate - Urothelial cells" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA059749: AB_2732639, HPA076768: AB_2732322" "unprognostic (3.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.77e-3)" "unprognostic (4.14e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (7.21e-2)" "unprognostic (3.38e-2)" "unprognostic (3.62e-1)" "unprognostic (2.42e-2)" "unprognostic (4.48e-1)" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.5;Ductal cells: 27.2;Endothelial cells: 29.3;Exocrine glandular cells: 21.9;Intestinal goblet cells: 25.5;Paneth cells: 21.4;Proximal enterocytes: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80209331 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;skin 1: 14.4;vagina: 7.3" "Cell type enhanced" "Detected in many" "Microglial cells: 6.4;Oligodendrocytes: 10.9;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 11.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Aggresome,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Aggresome "HPA023388: AB_1846020" "unprognostic (9.79e-3)" "unprognostic (3.86e-2)" "unprognostic (4.26e-1)" "unprognostic (1.05e-5)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.92e-4)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (3.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.62e-8)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 13.4;Hofbauer cells: 25.7;Kupffer cells: 17.0;Langerhans cells: 16.8;Macrophages: 22.3;monocytes: 31.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 20.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;intestine: 13.4;lymphoid tissue: 21.6" "Cell type enhanced" "Detected in some" "B-cells: 10.8;Bipolar cells: 7.1;dendritic cells: 7.5;Excitatory neurons: 10.5;Horizontal cells: 11.5;Inhibitory neurons: 8.5;T-cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Leukemia: 26.9;lymphoma: 40.6;Myeloma: 23.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA041402: AB_10795591" "unprognostic (1.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.35e-2)" "unprognostic (6.37e-2)" "unprognostic (5.47e-3)" "unprognostic (4.27e-4)" "unprognostic (1.38e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (5.14e-10)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-2)" CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 571.0;eosinophil: 408.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 571.0" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 94000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" CCDC125 KENAE ENSG00000183323 "Coiled-coil domain containing 125" Q86Z20 5 69280175-69332809 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 44.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.0;neutrophil: 11.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.0" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041878 Approved Uncertain "Nucleoplasm,Nuclear membrane,Intermediate filaments" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 73: Prostatic glandular cells - Transcription" "Nuclear membrane, Intermediate filaments" Nucleoplasm "HPA041878: AB_10796787" "prognostic unfavorable (8.06e-4)" "unprognostic (1.01e-1)" "unprognostic (2.35e-2)" "prognostic favorable (4.40e-4)" "unprognostic (1.05e-1)" "unprognostic (1.91e-2)" "unprognostic (8.21e-2)" "unprognostic (3.08e-2)" "unprognostic (4.06e-2)" "unprognostic (5.07e-2)" "unprognostic (2.52e-2)" "unprognostic (1.91e-2)" "unprognostic (2.05e-2)" "unprognostic (5.40e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "prognostic favorable (2.51e-4)" CCDC146 "KIAA1505, MBO2" ENSG00000135205 "Coiled-coil domain containing 146" Q8IYE0 7 77122434-77329533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 417.8;Endometrial ciliated cells: 439.8;Oligodendrocyte precursor cells: 144.9;Respiratory ciliated cells: 272.1;Spermatocytes: 126.4" "Group enriched" "Detected in all" 4 "endometrial cancer: 8.8;ovarian cancer: 13.6;renal cancer: 15.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.4" "Group enriched" "Detected in many" 4 "granulocytes: 15.4;NK-cells: 5.3;T-cells: 4.4" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA020082, HPA020105" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 56: Neurons - Neuronal signaling" "Cluster 56: Ciliated cells - Cilium assembly" "HPA020082: AB_1852410, HPA020105: AB_2072056" "unprognostic (3.07e-3)" "unprognostic (9.94e-3)" "unprognostic (1.56e-1)" "unprognostic (2.54e-3)" "unprognostic (1.85e-1)" "prognostic favorable (7.37e-4)" "unprognostic (1.95e-3)" "unprognostic (8.02e-3)" "unprognostic (4.05e-4)" "unprognostic (1.73e-1)" "unprognostic (4.63e-1)" "unprognostic (4.09e-2)" "unprognostic (7.38e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-1)" "unprognostic (2.70e-3)" "unprognostic (5.58e-3)" CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "head and neck cancer: 6.1;Leukemia: 21.8;lymphoma: 23.4;Myeloma: 15.7" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enhanced" "Detected in some" "Adipocytes: 124.2;Endothelial cells: 257.9;Fibroblasts: 84.2;Kupffer cells: 45.0;Late spermatids: 56.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1411.1;Macrophages: 1080.9;monocytes: 1343.3;NK-cells: 4730.9;T-cells: 2177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Cancer enriched" "Detected in some" 5 "lymphoma: 53.2" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.5;Extravillous trophoblasts: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: Non-specific - Transcription" "Cluster 43: Non-specific - Cell proliferation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139696 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 35.8" "Group enriched" "Detected in some" 6 "B-cells: 15.9;T-cells: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 77.4;T-cells: 74.5" "Cancer enhanced" "Detected in some" "liver cancer: 6.2" "Adipose subcutaneous - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Not detected" "Not detected" "CAB006820, HPA014488" Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 35: Liver cancer - Metabolism" "Cluster 2: T-cells - T-cell receptor" "CAB006820: , HPA014488: AB_1846639" "unprognostic (1.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.07e-3)" "unprognostic (2.08e-1)" "unprognostic (8.43e-2)" "unprognostic (2.05e-4)" "unprognostic (2.39e-1)" "unprognostic (4.98e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-4)" "unprognostic (3.74e-2)" "unprognostic (7.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.8;Hofbauer cells: 50.5;Langerhans cells: 45.2;Macrophages: 49.2;monocytes: 93.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 6.6" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 64.7;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 51.7;Endothelial cells: 41.7;Squamous epithelial cells: 47.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Prostate - Endothelial cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: Skin cancer - Membrane components" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "Microglial cells: 21.9;NK-cells: 103.3;Oligodendrocytes: 25.1;Schwann cells: 30.0;T-cells: 52.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "Leukemia: 7.1;lymphoma: 10.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 16.8" "Cell type enhanced" "Detected in some" "Kupffer cells: 12.7;Macrophages: 7.4;monocytes: 15.7;NK-cells: 40.4;T-cells: 18.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 472.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 472.1" "Cancer enriched" "Detected in some" 14 "Leukemia: 15.0" "Adipose subcutaneous - T-cells, Adipose visceral - Mesothelial cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 280000 "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (6.11e-3)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (6.95e-6)" "unprognostic (5.79e-2)" "unprognostic (1.43e-4)" "unprognostic (1.93e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (5.40e-4)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1698.7;dendritic cells: 539.1;granulocytes: 459.9;Hofbauer cells: 485.4;Langerhans cells: 414.6;monocytes: 749.0;NK-cells: 383.4;T-cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 70.9;lymphoma: 194.7" "Breast - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 4 "NK-cells: 96.8;T-cells: 326.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Cancer enriched" "Detected in some" 7 "Leukemia: 19.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Ductal cells: 952.6;Exocrine glandular cells: 924.6;granulocytes: 1130.6;Langerhans cells: 2369.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 361.7;granulocytes: 198.2;Hofbauer cells: 226.3;Kupffer cells: 257.1;Macrophages: 195.3;monocytes: 853.5;NK-cells: 408.9;Schwann cells: 201.6;T-cells: 432.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 207.9;Myeloma: 445.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1905.6;Hofbauer cells: 979.8;Langerhans cells: 748.0;Macrophages: 564.3;monocytes: 1697.8;NK-cells: 487.7;T-cells: 1243.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 272.6;lymphoma: 602.8" "Adipose visceral - T-cells, Breast - T-cells, Lung - Macrophages, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 19: Macrophages - Innate immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 14 "NK-cells: 1172.5;T-cells: 544.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Group enriched" "Detected in some" 7 "Leukemia: 49.8;liver cancer: 16.2;Myeloma: 24.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609979-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 65.0" "Cell type enhanced" "Detected in many" "B-cells: 82.0;dendritic cells: 17.4;Hofbauer cells: 18.3;Langerhans cells: 17.0;Macrophages: 17.9;monocytes: 18.5;NK-cells: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 232.9;naive B-cell: 413.5" "Lineage enriched" "Detected in all" 20 "B-cells: 413.5" "Group enriched" "Detected in some" 25 "Leukemia: 21.9;lymphoma: 36.3" "Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in single" "CAB002505, HPA044658" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 62: B-cells - B-cell activation" "Nucleoplasm, Mitochondria" "CAB002505: AB_563629, HPA044658: AB_2679039" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (7.81e-2)" "unprognostic (7.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (2.49e-8)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.59e-2)" CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enhanced" "Detected in many" "B-cells: 497.2;monocytes: 88.7;Plasma cells: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cancer enriched" "Detected in many" 6 "lymphoma: 593.0" "Prostate - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 153.9;Kupffer cells: 66.3;Langerhans cells: 193.7;Macrophages: 137.3;Microglial cells: 76.6;monocytes: 280.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 6 "NK-cells: 121.7;T-cells: 195.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cancer enhanced" "Detected in many" "Leukemia: 31.4;skin cancer: 16.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 193.5;esophagus: 87.1;liver: 86.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 247.8;Hepatocytes: 136.8;Kupffer cells: 93.1;monocytes: 75.0;Paneth cells: 147.4;Proximal enterocytes: 119.0;Suprabasal keratinocytes: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1234.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 1234.7" "Cancer enhanced" "Detected in many" "cervical cancer: 197.6" "Lung - Neutrophil_2, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 50: Enterocytes - Absorption" Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 310.3;Excitatory neurons: 441.1;Inhibitory neurons: 467.6;Oligodendrocyte precursor cells: 425.5;Oligodendrocytes: 634.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: Non-specific - RNA binding" "Cluster 32: Neurons - Synaptic function" "Plasma membrane, Cytosol" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.6;Distal enterocytes: 29.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 258.8;Distal enterocytes: 274.4;Glandular and luminal cells: 317.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 46.4;Rod photoreceptor cells: 59.4;Spermatocytes: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 2.5;T-cells: 6.5" "Low cancer specificity" "Detected in all" "Breast - Smooth muscle cells, Heart muscle - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 68: Kidney - Mixed function" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "HPA018151: AB_1846457, HPA023870: AB_1846459" "unprognostic (7.89e-2)" "unprognostic (1.55e-1)" "unprognostic (5.23e-2)" "unprognostic (3.09e-1)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.06e-1)" "unprognostic (9.86e-2)" "unprognostic (3.04e-1)" "unprognostic (2.04e-2)" "unprognostic (3.34e-3)" "unprognostic (1.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.67e-3)" CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 38: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 72: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" CEACAM21 "FLJ13540, R29124_1" ENSG00000007129 "CEA cell adhesion molecule 21" Q3KPI0 19 41549518-41586844 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.5;lymphoid tissue: 10.2" "Cell type enriched" "Detected in some" 9 "Granulosa cells: 140.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 2.9;Myeloma: 5.5" "Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" HPA043411 Uncertain NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: RS4;11 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "HPA043411: AB_10794886" "unprognostic (2.55e-1)" "unprognostic (1.61e-3)" "unprognostic (5.73e-2)" "prognostic favorable (1.89e-5)" "unprognostic (2.57e-1)" "unprognostic (8.02e-4)" "unprognostic (3.04e-1)" "unprognostic (2.05e-3)" "unprognostic (1.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (3.37e-6)" "unprognostic (2.09e-1)" "unprognostic (3.67e-1)" "unprognostic (1.12e-3)" "unprognostic (1.37e-1)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.4;Basal respiratory cells: 29.0;Club cells: 31.6;Endometrial ciliated cells: 31.1;Glandular and luminal cells: 35.8;Ionocytes: 25.8;Respiratory ciliated cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 68: Kidney - Mixed function" "Cluster 5: Bronchus - Unknown function" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 728.7;Late spermatids: 1686.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 36: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" CERKL RP26 ENSG00000188452 "Ceramide kinase like" Q49MI3 2 181536672-181680665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.1;retina: 16.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 19.0;Endometrial ciliated cells: 44.0;Respiratory ciliated cells: 25.3;Rod photoreceptor cells: 26.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.7;Neuroblastoma: 2.5" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 14.5" "HPA035443, HPA035444, HPA043203" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 56: Ciliated cells - Cilium assembly" "Nucleoplasm, Cytosol" "HPA035443: AB_2674625, HPA035444: AB_10672093, HPA043203: " "unprognostic (7.52e-3)" "unprognostic (6.13e-3)" "unprognostic (2.09e-1)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (2.71e-3)" "unprognostic (2.59e-1)" "unprognostic (1.39e-2)" "unprognostic (2.76e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.25e-4)" "unprognostic (4.54e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (3.07e-2)" "unprognostic (8.45e-2)" CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.7;Distal enterocytes: 3.8;Gastric mucus-secreting cells: 3.0;Intestinal goblet cells: 10.6;Oligodendrocyte precursor cells: 5.3" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Cell type enhanced" "Detected in many" "Astrocytes: 48.7;Fibroblasts: 79.3;Leydig cells: 39.2;Muller glia cells: 65.6;Thymic epithelial cells: 49.3" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.7" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 183.7;Early spermatids: 39.0;Hepatocytes: 115.8" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.9;lung cancer: 3.4" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Enzymes" "Cluster 30: Breast - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.3" "Cell type enhanced" "Detected in many" "B-cells: 64.4;dendritic cells: 121.4;Langerhans cells: 102.3;Macrophages: 50.3;Microglial cells: 41.0;monocytes: 79.3;Schwann cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 29.1;eosinophil: 17.5;intermediate monocyte: 23.5;memory B-cell: 47.3;myeloid DC: 46.2;naive B-cell: 63.3;non-classical monocyte: 29.0;plasmacytoid DC: 48.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 52.2" "Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 14 "Adipocytes: 2811.5;Endothelial cells: 858.8" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 7 "Bone cancer: 7.1;Leukemia: 3.4;lung cancer: 2.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 66: Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" CLEC17A FLJ45910 ENSG00000187912 "C-type lectin domain containing 17A" Q6ZS10 19 14583084-14612035 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 18.2" "Cell type enhanced" "Detected in some" "B-cells: 21.7;Early spermatids: 4.3;Late spermatids: 11.5;Microglial cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 11 "memory B-cell: 21.5;naive B-cell: 43.1" "Lineage enriched" "Detected in many" 14 "B-cells: 43.1" "Cancer enriched" "Detected in some" 8 "lymphoma: 13.9" "Lung - B-cells, Prostate - T-cells, Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "unprognostic (4.71e-5)" "unprognostic (1.34e-2)" "unprognostic (9.64e-4)" "unprognostic (5.02e-3)" "unprognostic (3.90e-1)" "unprognostic (9.00e-4)" "unprognostic (3.18e-3)" "unprognostic (1.60e-3)" "unprognostic (1.32e-2)" "unprognostic (7.11e-2)" "unprognostic (3.78e-2)" "unprognostic (4.43e-2)" "unprognostic (9.13e-3)" "unprognostic (1.65e-1)" "unprognostic (5.91e-2)" "unprognostic (2.07e-1)" "unprognostic (1.23e-1)" CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 8 "Hofbauer cells: 34.4;Langerhans cells: 94.9;Macrophages: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Cancer enriched" "Detected in single" 141 "Leukemia: 14.0" "Kidney - Macrophages, Prostate - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 317.3;Schwann cells: 295.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3234.4;Cholangiocytes: 2581.1;Collecting duct cells: 3156.4;Hepatocytes: 3803.9;Muller glia cells: 6903.3" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cancer enhanced" "Detected in all" "cervical cancer: 1845.0" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 68: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.2" "Cell type enhanced" "Detected in many" "Ionocytes: 50.5;Respiratory ciliated cells: 41.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" Cytosol "HPA030847: AB_10601100" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-2)" "unprognostic (5.26e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-1)" "unprognostic (2.49e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-2)" "unprognostic (3.27e-2)" "unprognostic (2.91e-1)" "prognostic favorable (5.91e-4)" CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 89.4;Spermatocytes: 83.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 64: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 740.2;Excitatory neurons: 832.7;Inhibitory neurons: 682.3;Oligodendrocyte precursor cells: 978.1" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 239.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 375.8;Smooth muscle cells: 250.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Fibroblast_1" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 72: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 403.1;Endometrial stromal cells: 315.8;Endothelial cells: 337.2;Extravillous trophoblasts: 792.1;Fibroblasts: 297.6;Granulosa cells: 231.7;Sertoli cells: 229.4;Smooth muscle cells: 453.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 215.6" "Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 129.4;Fibroblasts: 126.5;Leydig cells: 61.6;Pancreatic endocrine cells: 61.8;Schwann cells: 50.9;Smooth muscle cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 233.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 175.7;Excitatory neurons: 182.8;Fibroblasts: 155.6;Smooth muscle cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 466.3;testis cancer: 373.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 90.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 11.2;Early spermatids: 37.7;Late spermatids: 23.9;Respiratory ciliated cells: 14.9;Spermatocytes: 50.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 31: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: AB_10601261" "unprognostic (7.43e-3)" "unprognostic (8.72e-2)" "unprognostic (1.42e-1)" "unprognostic (5.75e-2)" "unprognostic (2.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (6.45e-3)" "unprognostic (1.02e-1)" "unprognostic (6.82e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (8.11e-2)" "unprognostic (1.81e-6)" "unprognostic (9.91e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (2.02e-1)" COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 25 "Cardiomyocytes: 24900.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 27.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" CPNE5 "COPN5, CPN5, KIAA1599" ENSG00000124772 "Copine 5" Q9HCH3 6 36740775-36839444 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4;heart muscle: 92.7" "Cell type enhanced" "Detected in many" "B-cells: 33.3;Cardiomyocytes: 35.6;Excitatory neurons: 34.6;Horizontal cells: 41.0;Oligodendrocyte precursor cells: 35.1;Plasma cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 11.3" "Region enhanced" "Detected in many" "basal ganglia: 62.4" "Group enriched" "Detected in some" 80 "memory B-cell: 51.6;naive B-cell: 26.8" "Lineage enriched" "Detected in single" 105 "B-cells: 51.6" "Group enriched" "Detected in many" 5 "lymphoma: 18.1;Myeloma: 29.2" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enhanced" "Detected in many" "basal ganglia: 103.3" "Region enhanced" "Detected in many" "basal ganglia: 135.5" HPA031369 Enhanced Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Cytosol "HPA031369: AB_10601801" "unprognostic (5.71e-3)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.73e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-3)" "unprognostic (2.45e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.00e-5)" "unprognostic (1.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.00e-1)" "unprognostic (3.57e-1)" CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 113.9;Microglial cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 145.5;Oligodendrocytes: 282.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Group enriched" "Detected in some" 4 "B-cells: 41.1;Erythroid cells: 17.2;Hofbauer cells: 17.1;Kupffer cells: 35.6;Macrophages: 45.8;monocytes: 18.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 7 "Leukemia: 3.5;lymphoma: 1.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophil_2, Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 499.4;Kupffer cells: 270.2;Macrophages: 260.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1113.7" "Cell type enhanced" "Detected in many" "Adipocytes: 481.8;Cardiomyocytes: 794.5;Endothelial cells: 463.9;Smooth muscle cells: 314.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.1;memory CD4 T-cell: 80.4;naive B-cell: 109.9;T-reg: 115.6" "Group enriched" "Detected in all" 30 "B-cells: 109.9;T-cells: 115.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 26: Non-specific - Mitochondria" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 65: Breast cancer - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Cell type enhanced" "Detected in some" "Kupffer cells: 14.2;Macrophages: 10.9;monocytes: 13.5;NK-cells: 55.4;T-cells: 50.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Prostate - T-cells" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.7;Excitatory neurons: 75.3;Inhibitory neurons: 78.8;Oligodendrocyte precursor cells: 72.7;Oligodendrocytes: 56.3;Peritubular cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 63: Astrocytes - Nervous system maintenance" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Group enriched" "Detected in some" 8 "Schwann cells: 28.4;T-cells: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.9;skin cancer: 5.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Kidney - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 1: T-cells - Immune response" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.0;Squamous epithelial cells: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 8 "NK-cells: 922.6;T-cells: 340.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Cancer enriched" "Detected in some" 11 "Leukemia: 42.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "NK-cells: 31.3;Serous glandular cells: 15.1;Squamous epithelial cells: 13.8;Suprabasal keratinocytes: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Cancer enriched" "Detected in single" 6 "Leukemia: 5.6" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 88.1;T-cells: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 445.8" "Lineage enriched" "Detected in many" 5 "T-cells: 445.8" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0" "Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 1: T-cells - Immune response" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 2027.1;Hofbauer cells: 2756.8;Macrophages: 1698.2;monocytes: 1957.4;Plasma cells: 2225.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - T-cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009492, HPA072667" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 19: Macrophages - Innate immune response" "CAB009492: AB_2090309, HPA072667: " "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 91.2;Intestinal goblet cells: 32.2;Langerhans cells: 83.0;Proximal enterocytes: 42.4;Schwann cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 82.1;Exocrine glandular cells: 71.6;Fibroblasts: 70.5;Pancreatic endocrine cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.0;intestine: 34.8;skin 1: 54.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 320.4;Respiratory ciliated cells: 135.7;Squamous epithelial cells: 105.6;Suprabasal keratinocytes: 138.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.6" "Cancer enhanced" "Detected in many" "breast cancer: 18.1;Gastric cancer: 11.6" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 65: Breast cancer - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.2;intestine: 14.4;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "B-cells: 26.4;dendritic cells: 15.9;Hofbauer cells: 17.1;monocytes: 22.3;NK-cells: 33.8;T-cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 30 "Leukemia: 20.9;lymphoma: 27.0;Myeloma: 8.4" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Centrosome" "HPA042758: AB_10962357, HPA042839: AB_10959898" "unprognostic (5.94e-2)" "unprognostic (1.41e-3)" "unprognostic (4.26e-2)" "unprognostic (1.93e-3)" "unprognostic (1.21e-1)" "unprognostic (1.72e-3)" "unprognostic (3.91e-2)" "prognostic favorable (1.23e-4)" "unprognostic (7.76e-3)" "unprognostic (4.45e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.95e-4)" "prognostic favorable (7.51e-14)" "unprognostic (1.37e-3)" "unprognostic (1.27e-1)" "unprognostic (4.53e-2)" "prognostic favorable (5.62e-4)" DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.4;Erythroid cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.3" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 71: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.2;Inhibitory neurons: 21.1;Oligodendrocyte precursor cells: 21.7;Oligodendrocytes: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 15: Smooth muscle cells - Muscle contraction" "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: AB_2682491, HPA062700: AB_2684838" "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101561351-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.0;placenta: 17.8" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 9.5;testis cancer: 5.2" "Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 4.4;hippocampal formation: 5.6" HPA073684 Supported Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" DIPK1A "FAM69A, FLJ23493" ENSG00000154511 "Divergent protein kinase domain 1A" Q5T7M9 1 92832737-92961522 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 80.0;Excitatory neurons: 112.0;Inhibitory neurons: 142.4;Oligodendrocyte precursor cells: 126.1;Oligodendrocytes: 152.4;Plasma cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 79.3" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015718, HPA017281" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 18: Non-specific - Mixed function" Cytosol Nucleoplasm "HPA015718: AB_1848405, HPA017281: AB_1848406" "prognostic favorable (8.96e-4)" "unprognostic (1.00e-1)" "unprognostic (6.17e-2)" "unprognostic (1.50e-3)" "unprognostic (1.43e-1)" "unprognostic (3.77e-3)" "unprognostic (3.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.45e-7)" "unprognostic (1.26e-2)" "unprognostic (5.99e-2)" "unprognostic (2.57e-1)" "unprognostic (1.66e-2)" DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 64.6;Endothelial cells: 51.4;Intestinal goblet cells: 28.8;Undifferentiated cells: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.2;lung cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" DMXL1 ENSG00000172869 "Dmx like 1" Q9Y485 5 119037772-119249138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 143.8;Oligodendrocytes: 211.5;Prostatic glandular cells: 185.3" "Cancer enhanced" "Detected in all" "prostate cancer: 14.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036431, HPA036432" Approved Approved "Nucleoli,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 73: Prostatic glandular cells - Transcription" "Nucleoli, Nucleoli fibrillar center" Cytosol "HPA036431: AB_10669791, HPA036432: AB_2675120" "unprognostic (2.47e-1)" "unprognostic (4.84e-2)" "unprognostic (7.87e-3)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-1)" "unprognostic (6.77e-2)" "unprognostic (1.40e-1)" "unprognostic (4.88e-2)" "unprognostic (5.93e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.16e-5)" "unprognostic (4.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.12e-2)" "unprognostic (5.18e-2)" DNAJC15 "DNAJD1, MCJ" ENSG00000120675 "DnaJ heat shock protein family (Hsp40) member C15" Q9Y5T4 13 43023203-43114213 "Disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 496.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: Non-specific - Nuclear processes" "Cluster 70: Basal prostatic cells - Lipid metabolism" "unprognostic (1.12e-1)" "unprognostic (2.89e-2)" "unprognostic (1.09e-2)" "unprognostic (2.97e-2)" "unprognostic (1.53e-2)" "unprognostic (3.07e-3)" "unprognostic (3.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.38e-2)" "unprognostic (3.40e-1)" "unprognostic (2.50e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-1)" "unprognostic (5.92e-3)" "unprognostic (3.17e-1)" DNALI1 "dJ423B22.5, hp28, P28" ENSG00000163879 "Dynein axonemal light intermediate chain 1" O14645 1 37556919-37566857 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 54.5" "Group enriched" "Detected in many" 4 "Early spermatids: 540.8;Endometrial ciliated cells: 311.6;Late spermatids: 1089.8;Respiratory ciliated cells: 385.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028305, HPA031633" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 36: Spermatids - Spermatogenesis" "HPA028305: AB_10601807, HPA031633: " "unprognostic (1.21e-2)" "unprognostic (9.04e-2)" "unprognostic (2.58e-2)" "unprognostic (6.09e-3)" "unprognostic (2.33e-1)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "prognostic favorable (6.02e-4)" "unprognostic (1.52e-1)" "unprognostic (5.50e-3)" "unprognostic (8.00e-3)" "unprognostic (3.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.19e-1)" "unprognostic (2.78e-2)" "unprognostic (1.47e-1)" "unprognostic (5.52e-2)" DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1616.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in many" "Adipocytes: 383.0;Oligodendrocytes: 346.6" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 83.2;Extravillous trophoblasts: 87.3;Oligodendrocyte precursor cells: 107.8;Oligodendrocytes: 98.3;Theca cells: 74.3" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2048.3;Cardiomyocytes: 1098.0;Squamous epithelial cells: 1850.5;Suprabasal keratinocytes: 4808.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSG00000140279 "Dual oxidase 2" Q9NRD8 15 45092650-45114172 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 290.2;thyroid gland: 75.7;urinary bladder: 92.8" "Group enriched" "Detected in many" 4 "Ductal cells: 252.8;Exocrine glandular cells: 324.2;Gastric mucus-secreting cells: 91.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 60.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder cancer: 1.1;cervical cancer: 3.5;Esophageal cancer: 2.2;head and neck cancer: 4.0" "Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (3.19e-1)" "unprognostic (7.51e-2)" "unprognostic (3.77e-2)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (7.93e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (9.59e-3)" "unprognostic (7.11e-2)" "unprognostic (5.32e-5)" "unprognostic (1.71e-1)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" "unprognostic (1.63e-2)" EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 63 "epididymis: 98.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.9;Rod photoreceptor cells: 4.6;Suprabasal keratinocytes: 8.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 52: Spermatids - Smell perception" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.08e-4)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (3.22e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-3)" "unprognostic (2.93e-2)" "unprognostic (9.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (4.20e-1)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 342.4;NK-cells: 489.6;Proximal enterocytes: 295.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Macrophages, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Astrocytes: 282.2;Excitatory neurons: 786.9;Inhibitory neurons: 364.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 281.0;Salivary duct cells: 238.8;Syncytiotrophoblasts: 433.6" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 150.6;Alveolar cells type 1: 234.1;Leydig cells: 96.7;Peritubular cells: 97.0;Sertoli cells: 102.3;Smooth muscle cells: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 156.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 12: Non-specific - Chromatin organization" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 287.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 518.7;Basal respiratory cells: 394.5;Club cells: 415.3;Glandular and luminal cells: 411.1;Mucus glandular cells: 530.1;Salivary duct cells: 463.9;Squamous epithelial cells: 392.3;Suprabasal keratinocytes: 389.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "Golgi apparatus" "HPA050923: AB_2681275, HPA060734: AB_2684351" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.38e-1)" "unprognostic (6.79e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (7.08e-2)" EML1 "ELP79, EMAP, EMAPL, HuEMAP" ENSG00000066629 "EMAP like 1" O00423 14 99737693-99942060 "Disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 77.5;Excitatory neurons: 56.6;Late spermatids: 63.1;Microglial cells: 67.5;Oligodendrocytes: 58.3;Rod photoreceptor cells: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033137, HPA049105" Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 44: Photoreceptor cells - Visual perception" "CAB033137: AB_2098052, HPA049105: AB_2680633" "unprognostic (9.86e-3)" "unprognostic (2.54e-1)" "unprognostic (8.18e-2)" "unprognostic (2.77e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (2.68e-2)" "unprognostic (8.09e-3)" "unprognostic (7.83e-2)" "unprognostic (3.06e-3)" "unprognostic (1.89e-2)" "unprognostic (9.98e-2)" "unprognostic (4.09e-3)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.81e-3)" "unprognostic (7.03e-3)" EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 774.7;Hofbauer cells: 898.0;Langerhans cells: 2220.9;Macrophages: 697.4;Melanocytes: 1260.9;monocytes: 1112.9" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 75: Myeloid cells - Innate immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in all" "Adipocytes: 806.3;Endothelial cells: 632.7;Extravillous trophoblasts: 338.4;Syncytiotrophoblasts: 369.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Approved "Nucleoplasm,Actin filaments,Cytokinetic bridge,Cytosol" Yes NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Enzymes" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "Actin filaments, Cytokinetic bridge, Cytosol" "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Late spermatids: 349.9;Microglial cells: 422.3;Muller glia cells: 397.8;Rod photoreceptor cells: 1231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 21.9;Squamous epithelial cells: 33.3;Suprabasal keratinocytes: 34.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.5;Glandular and luminal cells: 169.4;Ionocytes: 161.9;Squamous epithelial cells: 161.5;Suprabasal keratinocytes: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Group enriched" "Detected in some" 8 "Distal enterocytes: 172.4;Enteroendocrine cells: 78.7;Gastric mucus-secreting cells: 75.7;Intestinal goblet cells: 93.6;Late spermatids: 153.2;Paneth cells: 127.0;Proximal enterocytes: 281.2;Undifferentiated cells: 81.3" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 61.5;Gastric cancer: 28.2" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 287.6;Inhibitory neurons: 475.5;Microglial cells: 208.0;Oligodendrocyte precursor cells: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 37: Neurons - Neuronal signaling" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 38: Heart - Muscle contraction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 74: Pancreatic cells - Mixed function" "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favorable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "dendritic cells: 63.4;Mucus glandular cells: 35.0;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.2;Early spermatids: 22.0;Endometrial stromal cells: 16.4;Salivary duct cells: 21.8;Sertoli cells: 27.6;Smooth muscle cells: 84.7" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.2;testis cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 41: Non-specific - Cilium assembly" "Cluster 72: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" FAM178B LOC51252 ENSG00000168754 "Family with sequence similarity 178 member B" Q8IXR5 2 96875882-96986580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 18.9;brain: 10.5;epididymis: 5.5;lymphoid tissue: 12.1;testis: 8.2" "Cell type enriched" "Detected in some" 7 "Erythroid cells: 160.0" "Cancer enriched" "Detected in many" 5 "melanoma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 6.9;skin cancer: 9.9" "Prostate - Smooth muscle cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 2.4" "HPA042516, HPA062110" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" "Nuclear speckles" "Golgi apparatus" "HPA042516: AB_10806241, HPA062110: " "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" "unprognostic (8.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.28e-2)" "unprognostic (9.02e-4)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (6.49e-3)" "unprognostic (1.49e-1)" "unprognostic (5.13e-2)" "unprognostic (9.82e-11)" "unprognostic (6.93e-2)" "unprognostic (1.57e-1)" "unprognostic (9.63e-3)" "unprognostic (1.08e-1)" FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 8 "Early spermatids: 199.5;Late spermatids: 140.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 52: Spermatids - Smell perception" "Cluster 49: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.0;Basal squamous epithelial cells: 18.8;Late spermatids: 12.5;Squamous epithelial cells: 27.5;Suprabasal keratinocytes: 55.8" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 1.2;Esophageal cancer: 1.8;head and neck cancer: 3.5" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.8;Enteroendocrine cells: 54.8;Gastric mucus-secreting cells: 127.6;Intestinal goblet cells: 162.1;Paneth cells: 66.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.7;Gastric cancer: 11.6" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 112.5;Inhibitory neurons: 168.4;Microglial cells: 62.0;Syncytiotrophoblasts: 289.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 7 "NK-cells: 72.9;T-cells: 26.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: DU4475 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.5;Endothelial cells: 30.5;Fibroblasts: 25.2;Inhibitory neurons: 33.9;Microglial cells: 22.8;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 19.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Outer root sheath cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 17: Granulosa cells - Transcription regulation" Microtubules "HPA012583: AB_2668686" "unprognostic (8.69e-2)" "unprognostic (3.35e-3)" "unprognostic (2.92e-2)" "unprognostic (4.29e-2)" "unprognostic (5.47e-3)" "unprognostic (8.36e-2)" "unprognostic (7.61e-7)" "unprognostic (5.79e-2)" "unprognostic (1.63e-1)" "unprognostic (6.32e-2)" "unprognostic (1.18e-2)" "unprognostic (9.25e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (5.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Group enriched" "Detected in many" 4 "Hofbauer cells: 203.5;Kupffer cells: 184.5;Langerhans cells: 426.8;Macrophages: 271.2;monocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cancer enriched" "Detected in some" 5 "Leukemia: 31.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "dendritic cells: 19.5;Langerhans cells: 17.7;Oligodendrocytes: 44.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 33.4;lymphoma: 45.9" "Adipose subcutaneous - Macrophages, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 4: Platelets - Platelet activation" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Group enriched" "Detected in some" 10 "Endothelial cells: 77.4;Fibroblasts: 196.9;Kupffer cells: 94.7" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 8 "B-cells: 84.9;Early spermatids: 63.0;Plasma cells: 227.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 27 "lymphoma: 21.2;Myeloma: 7.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" FCRL6 "FcRH6, FLJ16056, IFGP6" ENSG00000181036 "Fc receptor like 6" Q6DN72 1 159800511-159816257 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 12.8" "Cell type enriched" "Detected in some" 4 "NK-cells: 107.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 142.9;memory CD8 T-cell: 134.3;naive CD8 T-cell: 102.8;NK-cell: 51.3" "Group enriched" "Detected in many" 26 "NK-cells: 51.3;T-cells: 142.9" "Not detected" "Not detected" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (2.64e-3)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.62e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (5.79e-3)" "unprognostic (6.65e-3)" "unprognostic (2.76e-2)" "unprognostic (3.91e-1)" "unprognostic (1.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.52e-5)" "unprognostic (3.98e-1)" "unprognostic (1.13e-1)" "unprognostic (8.78e-2)" "unprognostic (9.18e-2)" FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 66.4;dendritic cells: 58.3;Kupffer cells: 85.5;Langerhans cells: 53.1;Macrophages: 56.6;Microglial cells: 42.0;monocytes: 117.4;Schwann cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Group enriched" "Detected in some" 6 "Leukemia: 2.8;lymphoma: 9.5;Myeloma: 3.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" FGD3 "FLJ00004, ZFYVE5" ENSG00000127084 "FYVE, RhoGEF and PH domain containing 3" Q5JSP0 9 92947523-93036236 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.4;lymphoid tissue: 32.4" "Cell type enhanced" "Detected in many" "Early spermatids: 56.0;Late spermatids: 95.0;monocytes: 32.7;NK-cells: 61.0;T-cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 23.9" "Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA020963, HPA021018" Approved Approved Nucleoplasm,Cytosol NA NA 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Cytosol" "HPA020963: AB_2670542, HPA021018: AB_2670564" "unprognostic (5.66e-3)" "prognostic favorable (5.51e-4)" "unprognostic (5.05e-3)" "unprognostic (1.75e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.23e-7)" "unprognostic (2.26e-1)" "unprognostic (1.03e-2)" "unprognostic (2.61e-2)" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.32e-1)" "unprognostic (8.56e-2)" "unprognostic (3.96e-1)" "unprognostic (1.60e-1)" "unprognostic (9.66e-2)" "unprognostic (1.22e-2)" FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.0;Distal tubular cells: 46.6;Endometrial stromal cells: 41.8;Fibroblasts: 162.4;Leydig cells: 76.4;Smooth muscle cells: 59.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder cancer: 6.4;Bone cancer: 7.8;Brain cancer: 6.2;head and neck cancer: 8.9;Sarcoma: 13.5" "Prostate - Fibroblasts, Skin - Endothelial cells" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 15 "Early spermatids: 894.2;Late spermatids: 1672.0" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 59: Fibroblasts - Metabolism" "Cluster 36: Spermatids - Spermatogenesis" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Group enriched" "Detected in some" 5 "dendritic cells: 60.8;Inhibitory neurons: 58.6;Kupffer cells: 51.4;Langerhans cells: 21.3;Macrophages: 18.4;monocytes: 18.2;Schwann cells: 52.0" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Cancer enriched" "Detected in single" 66 "Leukemia: 29.2" "Prostate - Macrophages, Stomach - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 277.6;lymphoid tissue: 104.9" "Cell type enhanced" "Detected in many" "B-cells: 102.2;dendritic cells: 123.8;Kupffer cells: 94.2;Langerhans cells: 178.4;Macrophages: 113.9;monocytes: 208.5;NK-cells: 191.6;Schwann cells: 91.4;T-cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Leukemia: 72.1;lymphoma: 88.8;Myeloma: 125.1" "Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA008129: AB_1848963, HPA028288: AB_10612110" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (8.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (5.44e-2)" "unprognostic (6.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "prognostic unfavorable (4.23e-8)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.16e-1)" FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 3183.4;Fibroblasts: 713.4;Hepatocytes: 809.9;Pancreatic endocrine cells: 523.8;Smooth muscle cells: 552.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 4649.5;thyroid cancer: 4327.2" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 227000000000000 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Cell type enhanced" "Detected in some" "Endothelial cells: 18.6;Fibroblasts: 18.4;Microglial cells: 6.4;Smooth muscle cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 12.5" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.0;Basal squamous epithelial cells: 56.4;Club cells: 82.4;Gastric mucus-secreting cells: 202.7;Mucus glandular cells: 83.0;Salivary duct cells: 145.3;Squamous epithelial cells: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 52.3" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: DU4475 - Unknown function" "Cluster 58: Gastric mucus-secreting cells - Digestion" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 64.2;Kupffer cells: 29.6;Langerhans cells: 301.0;Macrophages: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Cancer enriched" "Detected in some" 5 "Gastric cancer: 6.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 94.6;Cardiomyocytes: 80.6;Cone photoreceptor cells: 108.6;Early spermatids: 97.7;Inhibitory neurons: 68.1;Late spermatids: 142.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 72: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.5;fallopian tube: 13.7;liver: 17.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.3;Collecting duct cells: 27.6;Early spermatids: 81.9;Hepatocytes: 27.1;Late spermatids: 98.7;Respiratory ciliated cells: 32.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in some" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: Non-specific - Cilium assembly" "Cluster 77: Cardiomyocytes - Muscle contraction" "unprognostic (6.12e-5)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (9.19e-3)" "unprognostic (4.77e-3)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (3.71e-1)" "unprognostic (2.86e-4)" "unprognostic (3.84e-2)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-3)" FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917899-45995824 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 263.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 87.9;Skeletal myocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Fibroblast_1, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;retina: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 211.6;Inhibitory neurons: 324.6;Oligodendrocyte precursor cells: 944.9;Oligodendrocytes: 375.9" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 9.9;Neuroblastoma: 11.5" "Lung - Alveolar cells type 1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" "HPA060775: AB_2684358" "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Group enriched" "Detected in many" 4 "monocytes: 38.2;NK-cells: 74.0;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 11.7;lymphoma: 11.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" GCSAM "GCET2, HGAL, MGC40441" ENSG00000174500 "Germinal center associated signaling and motility" Q8N6F7 3 112120839-112133270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 29.3;skin 1: 16.4" "Cell type enhanced" "Detected in some" "B-cells: 14.0;dendritic cells: 4.9;Schwann cells: 10.7;T-cells: 9.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 41.1" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA002473 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 23: Langerhans cells - Immune response" "HPA002473: AB_1078960" "unprognostic (8.23e-4)" "unprognostic (1.64e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (2.33e-1)" "unprognostic (4.17e-3)" "unprognostic (9.20e-2)" "unprognostic (8.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.69e-3)" "unprognostic (1.97e-1)" "unprognostic (5.78e-2)" "unprognostic (3.32e-2)" "unprognostic (3.77e-1)" "unprognostic (3.43e-2)" "unprognostic (2.35e-2)" "unprognostic (2.38e-2)" GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 311.1;Fibroblasts: 168.2;granulocytes: 138.7;Langerhans cells: 122.7;Smooth muscle cells: 204.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 72: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 53.7;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in some" "granulocytes: 5.1;Intestinal goblet cells: 16.9;NK-cells: 16.2;Plasma cells: 7.6;T-cells: 16.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "Leukemia: 62.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB011197: AB_532302" "unprognostic (5.67e-4)" "unprognostic (8.67e-3)" "prognostic favorable (5.68e-5)" "unprognostic (4.88e-3)" "unprognostic (3.57e-2)" "unprognostic (5.86e-3)" "unprognostic (2.06e-1)" "unprognostic (3.87e-3)" "unprognostic (1.26e-3)" "unprognostic (4.47e-3)" "unprognostic (5.20e-2)" "unprognostic (1.72e-1)" "unprognostic (6.80e-6)" "unprognostic (2.63e-1)" "unprognostic (8.27e-2)" "unprognostic (3.97e-1)" "unprognostic (4.37e-2)" GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 29.5;Fibroblasts: 64.4;Thymic epithelial cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cancer enhanced" "Detected in many" "Brain cancer: 40.9" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" "Golgi apparatus" "CAB034422: AB_2110748, HPA043313: AB_2678421, HPA063634: AB_2685067" "unprognostic (1.27e-1)" "prognostic favorable (1.71e-5)" "unprognostic (8.53e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (7.82e-3)" "unprognostic (3.88e-2)" "unprognostic (2.15e-3)" "unprognostic (8.55e-2)" "prognostic favorable (3.91e-5)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (3.89e-2)" "unprognostic (2.08e-1)" GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 211.3;Langerhans cells: 274.5;Macrophages: 158.1;Serous glandular cells: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Not detected" "Not detected" "Adipose visceral - T-cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" HPA023262 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Group enriched" "Detected in many" 6 "Adipocytes: 175.1;Endothelial cells: 132.5;Hofbauer cells: 44.1;Kupffer cells: 85.8;Macrophages: 56.2;monocytes: 99.4;NK-cells: 114.3;T-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 14 "Leukemia: 3.6" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Group enriched" "Detected in many" 6 "Adipocytes: 185.2;Endothelial cells: 224.0;Hofbauer cells: 119.8;Kupffer cells: 109.7;Macrophages: 128.3;monocytes: 122.4;NK-cells: 206.6;T-cells: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;pancreatic cancer: 9.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 7: NK-cells - Immune response regulation" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 94.7;Endothelial cells: 90.8;Hofbauer cells: 28.5;Kupffer cells: 55.9;Macrophages: 25.6;monocytes: 29.0;NK-cells: 52.6;T-cells: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cancer enriched" "Detected in some" 7 "Leukemia: 16.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 257.0;Endothelial cells: 309.4;Kupffer cells: 139.2;monocytes: 108.9;NK-cells: 378.3;T-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Cancer enriched" "Detected in single" 46 "Leukemia: 18.0" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 36: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 38.3;Fibroblasts: 9.8;Leydig cells: 25.1;Peritubular cells: 29.6;Theca cells: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 204.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.7;Hepatocytes: 51.0;Inhibitory neurons: 30.8" "Cancer enriched" "Detected in single" 4 "liver cancer: 1.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 129.0;Proximal enterocytes: 216.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 35.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 48.2;Astrocytes: 52.8;Extravillous trophoblasts: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 242.0" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 190000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.0;lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "B-cells: 19.0;dendritic cells: 17.7;Langerhans cells: 60.6;Macrophages: 28.9;monocytes: 66.2;NK-cells: 19.1;T-cells: 21.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 5.3;lymphoma: 13.9;Myeloma: 7.7" "Adipose visceral - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages" "HPA029694, HPA029695" Supported NA NA "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465342 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Early spermatids: 137.6;Late spermatids: 224.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045337 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Enzymes" "Cluster 51: Late spermatids - Spermatogenesis" "HPA045337: AB_10960528" "unprognostic (1.55e-1)" "unprognostic (3.00e-1)" "unprognostic (6.09e-3)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (8.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-5)" "unprognostic (1.33e-2)" "unprognostic (1.90e-1)" "unprognostic (2.71e-2)" "unprognostic (2.68e-3)" GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 54.2;Extravillous trophoblasts: 294.3;Syncytiotrophoblasts: 90.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Low cancer specificity" "Detected in many" "Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 83.4;stomach 1: 52.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 117.2;Inhibitory neurons: 127.9;Melanocytes: 268.2;Oligodendrocyte precursor cells: 124.7;Schwann cells: 245.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: DU4475 - Unknown function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nuclear bodies, Cytosol" "HPA036159: AB_10671835, HPA057384: AB_2683424" "unprognostic (3.91e-2)" "unprognostic (7.93e-2)" "unprognostic (3.14e-2)" "unprognostic (4.11e-4)" "unprognostic (5.03e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (4.82e-2)" "unprognostic (2.59e-2)" "unprognostic (9.90e-2)" "unprognostic (1.82e-2)" "unprognostic (4.54e-2)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.6;Horizontal cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 9: Neurons - Nervous system development" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enriched" "Detected in some" 4 "T-cells: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.3" "Lineage enriched" "Detected in many" 15 "T-cells: 110.3" "Group enriched" "Detected in some" 43 "Leukemia: 2.3;lymphoma: 7.6;Myeloma: 2.8" "Kidney - T-cells, Liver - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 1.8;dendritic cells: 2.2;Excitatory neurons: 2.3;Intestinal goblet cells: 2.4;Langerhans cells: 4.1;Plasma cells: 2.4;T-cells: 6.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.8;lymphoma: 4.8" "Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.6;Horizontal cells: 15.4;Kupffer cells: 21.1;Macrophages: 16.2;Rod photoreceptor cells: 16.5;T-cells: 13.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Not detected" "Not detected" "Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1868.9;Alveolar cells type 2: 560.9;Club cells: 437.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 41: Alveolar cells - Lung function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8" "Cell type enhanced" "Detected in many" "Macrophages: 53.9;NK-cells: 66.0;T-cells: 78.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Myeloma: 25.1" "Adipose visceral - T-cells, Prostate - T-cells, Skeletal muscle - Endothelial cells" "Region enhanced" "Detected in many" "basal ganglia: 16.2" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 19: Macrophages - Innate immune response" Nucleoli Nucleoplasm "HPA043148: AB_2678341, HPA057666: AB_2683496, HPA059092: AB_2683902" "unprognostic (9.05e-2)" "unprognostic (4.92e-2)" "prognostic favorable (7.22e-5)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.07e-3)" "unprognostic (3.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.34e-3)" "unprognostic (3.13e-1)" "prognostic favorable (8.33e-4)" "unprognostic (1.91e-1)" "unprognostic (5.35e-2)" "unprognostic (3.93e-1)" "unprognostic (7.82e-4)" GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 160.8;lymphoid tissue: 229.3" "Cell type enhanced" "Detected in many" "B-cells: 245.3;dendritic cells: 192.4;Hofbauer cells: 386.3;Kupffer cells: 280.3;Langerhans cells: 241.1;Macrophages: 236.3;monocytes: 375.3;NK-cells: 274.2;T-cells: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 54.8;lymphoma: 46.3" "Lung - Neutrophil_2, Prostate - T-cells, Skin - T-cells, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 73000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (2.93e-2)" "unprognostic (2.51e-2)" "unprognostic (2.02e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.66e-1)" "unprognostic (6.61e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (6.92e-9)" "unprognostic (2.01e-2)" "unprognostic (1.69e-2)" "unprognostic (5.47e-2)" "unprognostic (5.87e-2)" GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 404.2;Distal enterocytes: 464.1;Gastric mucus-secreting cells: 917.0;Hepatocytes: 893.8;Paneth cells: 428.3;Squamous epithelial cells: 354.7;Undifferentiated cells: 552.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1247.7" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "pons and medulla: 1.2" "Low region specificity" "Detected in some" HPA003545 Enhanced Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 91.0;Late spermatids: 237.9;Oligodendrocytes: 117.7;Rod photoreceptor cells: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 41.5;Basal squamous epithelial cells: 27.8;Squamous epithelial cells: 29.8;Suprabasal keratinocytes: 45.8" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9;pancreatic cancer: 2.3" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "HPA026317, HPA072904" Supported Approved Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA026317: AB_1854008, HPA072904: " "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 166.3;Proximal enterocytes: 38.6;Sertoli cells: 52.5;Syncytiotrophoblasts: 95.6;Thymic epithelial cells: 38.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 28: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2884.6;NK-cells: 1948.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cancer enriched" "Detected in some" 51 "lymphoma: 378.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 6 "NK-cells: 135.1;T-cells: 259.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 478.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 258.6;eosinophil: 458.7;neutrophil: 229.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 458.7" "Cancer enhanced" "Detected in all" "Myeloma: 392.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 5500000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: Non-specific - Nucleosome assembly" "Cluster 70: Basal prostatic cells - Lipid metabolism" "Nucleoplasm, Nucleoli rim" "CAB011507: AB_2117984, HPA055907: AB_2682966" "unprognostic (4.43e-2)" "unprognostic (1.57e-3)" "unprognostic (1.31e-2)" "unprognostic (2.96e-2)" "unprognostic (5.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.85e-1)" "unprognostic (8.93e-2)" "unprognostic (3.08e-1)" "prognostic favorable (8.06e-5)" H2BC9 "H2B/j, H2BFJ, HIST1H2BH" ENSG00000275713 "H2B clustered histone 9" Q93079 6 26251651-26253710 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.2;vagina: 4.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 27.6;Extravillous trophoblasts: 31.8;Paneth cells: 16.6;Plasma cells: 26.6;Proximal enterocytes: 15.1;Undifferentiated cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.7;neutrophil: 3.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 1: Non-specific - Nucleosome assembly" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (5.83e-2)" "unprognostic (6.27e-3)" "unprognostic (4.50e-2)" "unprognostic (9.18e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.06e-3)" "unprognostic (3.08e-3)" "unprognostic (1.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.86e-1)" "unprognostic (3.22e-1)" "unprognostic (2.96e-8)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-3)" HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 100.2;granulocytes: 48.8;Langerhans cells: 32.8;Melanocytes: 34.8;Pancreatic endocrine cells: 91.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Early spermatids: 18.7;Erythroid cells: 6.6;Late spermatids: 9.6;Plasma cells: 5.1;Spermatocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Prostate - T-cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 49: Non-specific - Unknown function" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 146.7;Langerhans cells: 78.0;Macrophages: 84.9;monocytes: 45.1;NK-cells: 136.3;Proximal tubular cells: 58.3;Schwann cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 13.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.7;Basal prostatic cells: 192.2;Basal respiratory cells: 54.1;Basal squamous epithelial cells: 139.8;Langerhans cells: 72.1;Squamous epithelial cells: 45.9;Suprabasal keratinocytes: 87.8" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Group enriched" "Detected in some" 5 "Bladder cancer: 7.1;cervical cancer: 3.9;Esophageal cancer: 4.9;Gallbladder cancer: 6.6;head and neck cancer: 12.4" "Adipose visceral - Adipocytes (Visceral), Lung - NK-cells (Lung), Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 191.8;Excitatory neurons: 370.7;Inhibitory neurons: 430.7;Microglial cells: 325.6;Oligodendrocyte precursor cells: 309.0;Oligodendrocytes: 220.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 74.1" "Group enriched" "Detected in all" 9 "B-cells: 52.6;dendritic cells: 74.1;monocytes: 24.4" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" HEATR9 "C17orf66, FLJ32830" ENSG00000270379 "HEAT repeat containing 9" A2RTY3 17 35854946-35868891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 10.1" "Group enriched" "Detected in some" 23 "Early spermatids: 79.3;Late spermatids: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA023129 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 36: Spermatids - Spermatogenesis" "HPA023129: AB_1845599" "unprognostic (1.02e-1)" "unprognostic (2.63e-3)" "unprognostic (5.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (7.44e-4)" "unprognostic (1.30e-3)" "unprognostic (2.43e-2)" "unprognostic (2.63e-1)" "unprognostic (3.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.61e-10)" "unprognostic (6.78e-2)" "unprognostic (1.93e-1)" "unprognostic (4.52e-2)" "unprognostic (5.61e-3)" HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 866.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" HEY2 "bHLHb32, HERP1, HESR2" ENSG00000135547 "Hes related family bHLH transcription factor with YRPW motif 2" Q9UBP5 6 125747664-125761269 "Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.1;Early spermatids: 43.3;Endometrial ciliated cells: 41.3;Glandular and luminal cells: 35.4;Granulosa cells: 70.3;Late spermatids: 79.3;Muller glia cells: 34.3;Smooth muscle cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030205, HPA074851" Approved Approved "Nuclear bodies,Aggresome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Nuclear bodies" Aggresome "HPA030205: AB_10600712, HPA074851: AB_2686718" "unprognostic (5.10e-2)" "unprognostic (4.34e-2)" "unprognostic (1.41e-3)" "unprognostic (2.43e-3)" "unprognostic (1.99e-1)" "unprognostic (2.52e-3)" "unprognostic (2.56e-1)" "unprognostic (1.38e-2)" "unprognostic (2.01e-1)" "unprognostic (9.10e-3)" "unprognostic (7.34e-2)" "unprognostic (6.20e-2)" "unprognostic (1.79e-1)" "unprognostic (2.28e-1)" "unprognostic (6.74e-2)" "unprognostic (1.51e-3)" "unprognostic (1.19e-1)" HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.1;Fibroblasts: 21.6;Inhibitory neurons: 22.0;Muller glia cells: 28.2;Smooth muscle cells: 62.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 105.6;Rhabdoid: 240.2" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 53: Connective tissue cells - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 78.9;Cholangiocytes: 146.3;dendritic cells: 58.6;Ductal cells: 102.4;Endothelial cells: 71.3;Hepatocytes: 56.4;Hofbauer cells: 72.2;Kupffer cells: 55.1;monocytes: 56.7" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 68.0" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 130.3;Oligodendrocyte precursor cells: 161.7;Oligodendrocytes: 111.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "B-cells: 63.7;dendritic cells: 54.8;Langerhans cells: 77.9;Macrophages: 40.5;monocytes: 27.4;Schwann cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.0" "Group enriched" "Detected in many" 11 "B-cells: 21.0;dendritic cells: 17.8;monocytes: 6.0" "Cancer enriched" "Detected in some" 4 "lymphoma: 15.1" "Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA045038: AB_10959457, HPA076922: " "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (3.83e-2)" "unprognostic (2.60e-1)" "unprognostic (9.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.68e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" "unprognostic (9.95e-2)" "unprognostic (3.65e-2)" "unprognostic (8.70e-2)" "unprognostic (5.94e-2)" HLA-F ENSG00000204642 "Major histocompatibility complex, class I, F" P30511 6 29722775-29738528 "Plasma proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 188.3" "Cell type enhanced" "Detected in many" "monocytes: 207.9;NK-cells: 382.8;Proximal enterocytes: 325.6;T-cells: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.07e-3)" "unprognostic (5.16e-2)" "unprognostic (3.05e-1)" "unprognostic (9.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (4.99e-2)" "unprognostic (2.68e-1)" "unprognostic (4.21e-3)" "unprognostic (2.43e-3)" "unprognostic (3.21e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (1.26e-1)" "unprognostic (2.95e-2)" "unprognostic (4.13e-2)" "unprognostic (1.30e-2)" HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.2;Endothelial cells: 32.4;Hofbauer cells: 38.3;Kupffer cells: 29.8;Langerhans cells: 28.6;Macrophages: 19.1;Thymic epithelial cells: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cancer enhanced" "Detected in many" "Leukemia: 23.3" "Breast - Endothelial cells, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 275.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 941.5;Ductal cells: 599.7;Extravillous trophoblasts: 705.5;Syncytiotrophoblasts: 701.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in some" "Astrocytes: 38.6;Distal enterocytes: 45.6;Enteroendocrine cells: 27.6;Intestinal goblet cells: 37.9;Paneth cells: 48.7;Proximal enterocytes: 137.9;Undifferentiated cells: 29.3" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;ovary: 31.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 75.4;Granulosa cells: 282.7;Ionocytes: 129.4;Peritubular cells: 89.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.4" "Group enriched" "Detected in some" 36 "memory B-cell: 14.9;naive B-cell: 26.6;plasmacytoid DC: 42.3" "Group enriched" "Detected in many" 108 "B-cells: 26.6;dendritic cells: 42.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 29.7" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" HSD17B13 "SCDR9, SDR16C3" ENSG00000170509 "Hydroxysteroid 17-beta dehydrogenase 13" Q7Z5P4 4 87303789-87322886 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 573.7" "Group enriched" "Detected in some" 4 "Adipocytes: 87.8;Hepatocytes: 109.3" "Cancer enriched" "Detected in some" 26 "liver cancer: 52.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "breast cancer: 2.0;lung cancer: 1.9" "Liver - Hepatocytes, Prostate - Urothelial cells" "Not detected" "Not detected" HPA029125 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "Golgi apparatus" "HPA029125: AB_10601580" "unprognostic (2.49e-1)" "unprognostic (7.46e-2)" "unprognostic (7.02e-2)" "unprognostic (1.86e-4)" "unprognostic (4.74e-2)" "unprognostic (8.44e-2)" "prognostic favorable (2.94e-4)" "prognostic favorable (7.80e-4)" "unprognostic (4.97e-1)" "unprognostic (2.22e-2)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (7.18e-4)" "unprognostic (3.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.52e-3)" HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 356.5;Endothelial cells: 341.2;Granulosa cells: 788.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;choroid plexus: 5.6" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 80.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.5" "Prostate - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 182.2;dendritic cells: 70.3;Early spermatids: 85.7;Hofbauer cells: 63.7;Late spermatids: 72.5;Spermatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 31.5;lymphoma: 38.8;Myeloma: 32.1" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in all" 6 "Adipocytes: 490.3;Endothelial cells: 276.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 146.4;Hepatocytes: 177.1;monocytes: 254.2;NK-cells: 246.5;Plasma cells: 138.3;T-cells: 179.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Group enriched" "Detected in all" 6 "Leukemia: 98.4;lymphoma: 73.3;Myeloma: 127.4" "Adipose subcutaneous - T-cells, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - T-cells, Lung - Neutrophil_2, Prostate - T-cells" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 10 "T-cells: 89.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Cancer enhanced" "Detected in some" "Leukemia: 2.4;lymphoma: 3.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 323.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 228.9;Inhibitory neurons: 237.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "amygdala: 194.3;basal ganglia: 212.9;cerebral cortex: 323.4;hippocampal formation: 320.5;white matter: 109.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" IFITM10 DSPA3 ENSG00000244242 "Interferon induced transmembrane protein 10" A6NMD0 11 1732406-1750595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 2.6;bone marrow: 1.5;brain: 3.2;choroid plexus: 1.8;retina: 1.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 10.3;Inhibitory neurons: 11.1;Oligodendrocyte precursor cells: 38.0;Respiratory ciliated cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "unprognostic (1.89e-3)" "unprognostic (2.10e-2)" "unprognostic (1.22e-6)" "unprognostic (6.49e-3)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" "unprognostic (3.66e-1)" "unprognostic (4.09e-1)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-1)" "unprognostic (2.44e-2)" "unprognostic (3.76e-2)" IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 56: Ciliated cells - Cilium assembly" Microtubules Cytosol "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" IGHD3-10 "DXP'1, IGHD310" ENSG00000211923 "Immunoglobulin heavy diversity 3-10" 14 105904497-105904527 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 1.3;intestine: 3.7;lymphoid tissue: 4.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "naive B-cell: 5.4" "Lineage enriched" "Detected in single" 55 "B-cells: 5.4" "Cancer enriched" "Detected in single" 10 "Leukemia: 5.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" IGHD3-3 "DXP4, IGHD33" ENSG00000211930 "Immunoglobulin heavy diversity 3-3" 14 105914359-105914389 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.3;lymphoid tissue: 2.6;salivary gland: 3.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 62.6" "Lineage enriched" "Detected in single" 626 "B-cells: 62.6" "Cancer enriched" "Detected in some" 7 "Leukemia: 8.0" "Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-1)" "unprognostic (1.75e-1)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Cell type enhanced" "Detected in some" "B-cells: 429.3;Basal keratinocytes: 123.6;Plasma cells: 568.0;T-cells: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Group enriched" "Detected in some" 38 "lymphoma: 133.9;Myeloma: 34.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 22 "Plasma cells: 2.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Group enriched" "Detected in some" 18 "Leukemia: 3.3;lymphoma: 4.1;Myeloma: 1.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 42 "Plasma cells: 4.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Cancer enriched" "Detected in some" 25 "Myeloma: 1264.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in some" 4 "B-cells: 2770.0;Plasma cells: 8854.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 17 "Leukemia: 375.1;lymphoma: 1452.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 224 "Plasma cells: 8312.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cancer enriched" "Detected in some" 40 "Myeloma: 1020.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 14 "Plasma cells: 4.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 153 "Plasma cells: 228.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.6" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in some" 578 "Plasma cells: 6301.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cancer enriched" "Detected in some" 4 "lymphoma: 125.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Cell type enriched" "Detected in some" 21 "Plasma cells: 97.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Cell type enriched" "Detected in single" 31 "Plasma cells: 3.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 88 "Plasma cells: 877.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 56: Neurons - Neuronal signaling" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Cell type enriched" "Detected in some" 259 "Plasma cells: 1191.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 45: Plasma cells - Humoral immune response" IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 215 "Plasma cells: 2255.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Group enriched" "Detected in some" 10 "Leukemia: 2.1;lymphoma: 3.6" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enriched" "Detected in some" 76 "Plasma cells: 353.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cancer enriched" "Detected in single" 225 "Myeloma: 25.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Cell type enriched" "Detected in single" 13 "Plasma cells: 1.3" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cancer enriched" "Detected in single" 140 "lymphoma: 14.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in some" 282 "Plasma cells: 6914.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 10 "Leukemia: 1.7;lymphoma: 3.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA006014: " IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 146 "Plasma cells: 1746.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 16 "Plasma cells: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Group enriched" "Detected in some" 20 "lymphoma: 1.6;Myeloma: 2.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 913 "Plasma cells: 4001.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cancer enriched" "Detected in single" 33 "Myeloma: 22.0" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 21 "Plasma cells: 1145.7" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 573 "Plasma cells: 2945.6" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Group enriched" "Detected in some" 21 "lymphoma: 3.1;Myeloma: 1.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 54 "Plasma cells: 335.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cancer enriched" "Detected in single" 4 "Myeloma: 2.8" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 139 "Plasma cells: 33.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cancer enhanced" "Detected in many" "Myeloma: 5.0" "Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 34: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Cell type enriched" "Detected in single" 92 "Plasma cells: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 196 "Plasma cells: 2962.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cancer enriched" "Detected in some" 49 "lymphoma: 78.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 550 "Plasma cells: 2239.3" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cancer enriched" "Detected in single" 44 "lymphoma: 12.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 213 "Plasma cells: 921.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cancer enriched" "Detected in many" 1355 "Myeloma: 4518.2" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Cell type enriched" "Detected in some" 9 "Plasma cells: 12.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Cancer enriched" "Detected in single" 125 "Myeloma: 21.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 521 "Plasma cells: 95.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Group enriched" "Detected in some" 25 "lymphoma: 1.9;Myeloma: 3.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 5 "Plasma cells: 163.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cancer enriched" "Detected in some" 58 "Myeloma: 3616.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 19 "Plasma cells: 242.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cancer enriched" "Detected in single" 389 "Myeloma: 110.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 219 "Plasma cells: 2096.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Cancer enriched" "Detected in some" 3236 "Myeloma: 8855.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Cell type enriched" "Detected in some" 7 "Plasma cells: 43.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Cancer enriched" "Detected in single" 360 "Myeloma: 58.6" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 160 "Plasma cells: 921.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 20 "Plasma cells: 33.0" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Group enriched" "Detected in some" 29 "Leukemia: 35.2;Myeloma: 52.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 91 "Plasma cells: 843.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 36 "Leukemia: 236.9;lymphoma: 904.2" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 34: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 51 "Plasma cells: 956.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 40: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 231 "Plasma cells: 6180.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 34: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 7 "Plasma cells: 41.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Cancer enriched" "Detected in single" 131 "lymphoma: 50.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 38.0;Enteroendocrine cells: 50.0;Granulosa cells: 136.8;Intestinal goblet cells: 40.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 12.8;Gastric cancer: 10.9" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 17: Granulosa cells - Transcription regulation" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 10.7;monocytes: 34.1;NK-cells: 55.5;Plasma cells: 12.1;T-cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 9.3;lymphoma: 22.4;Myeloma: 27.4" "Breast - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 124.4;dendritic cells: 118.0;Kupffer cells: 189.7;Langerhans cells: 109.0;monocytes: 69.2;NK-cells: 87.6;Plasma cells: 76.4;T-cells: 71.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 24 "Leukemia: 31.6;lymphoma: 39.9;Myeloma: 42.3;skin cancer: 16.3" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 46.8;Oligodendrocyte precursor cells: 36.1;Proximal tubular cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 15.7;Early spermatids: 15.4;Late spermatids: 22.8;Microglial cells: 14.6;Peritubular cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: DU4475 - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 97.8;NK-cells: 304.7;T-cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cancer enriched" "Detected in some" 10 "lymphoma: 85.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 112.9;dendritic cells: 93.7;Distal enterocytes: 87.2;Langerhans cells: 151.6;NK-cells: 284.8;Plasma cells: 91.0;Proximal enterocytes: 80.8;T-cells: 197.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 203.1;lymphoma: 129.5;Myeloma: 347.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA046641 Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Plasma membrane" "Endoplasmic reticulum" "HPA046641: AB_2679733" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Cell type enhanced" "Detected in many" "NK-cells: 204.9;Serous glandular cells: 318.6;T-cells: 1261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 78.3;Inhibitory neurons: 127.4;Late spermatids: 92.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "skin cancer: 72.2;testis cancer: 181.5" "Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 169.2;Early spermatids: 44.6;Peritubular cells: 86.8;Sertoli cells: 35.9;Smooth muscle cells: 100.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 81.2;Inhibitory neurons: 54.7;Microglial cells: 33.7;Oligodendrocyte precursor cells: 62.1;Smooth muscle cells: 104.5" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.7;Myeloma: 14.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.6;monocytes: 151.0;NK-cells: 195.1;T-cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 125 "Leukemia: 74.5;lymphoma: 40.6;Myeloma: 51.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 163.7;Gastric mucus-secreting cells: 166.3;Mucus glandular cells: 165.9;Salivary duct cells: 292.0;Schwann cells: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.8;Alveolar cells type 2: 101.5;Basal respiratory cells: 120.6;Collecting duct cells: 72.9;Ductal cells: 64.0;Exocrine glandular cells: 185.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 272.4;Extravillous trophoblasts: 74.6;Fibroblasts: 84.2;Microglial cells: 156.0;Smooth muscle cells: 85.0;Syncytiotrophoblasts: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 76.2;skin cancer: 74.2" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Cell type enhanced" "Detected in some" "granulocytes: 29.4;NK-cells: 75.1;Serous glandular cells: 22.9;T-cells: 127.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 44 "Leukemia: 7.3;lymphoma: 5.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847840 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 286.2;Inhibitory neurons: 179.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Immune cell enhanced" "Detected in many" "naive B-cell: 13.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 208.8" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 11 "Early spermatids: 152.7;Late spermatids: 168.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cancer enhanced" "Detected in many" "lymphoma: 25.3" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Liver - T-cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 45: Non-specific - Cell proliferation" "Cluster 1: T-cells - Immune response" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 25.3;Hofbauer cells: 17.5;monocytes: 21.5;NK-cells: 22.2;Plasma cells: 19.8;T-cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 11.5;lymphoma: 24.7;Myeloma: 19.8" "Breast - T-cells, Prostate - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 7 "dendritic cells: 275.0;Hofbauer cells: 105.6;Kupffer cells: 135.5;Langerhans cells: 331.4;Macrophages: 148.9;monocytes: 205.6;T-cells: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Group enriched" "Detected in some" 10 "Leukemia: 6.4;lymphoma: 15.9" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 82.7;monocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" JMJD7 ENSG00000243789 "Jumonji domain containing 7" P0C870 15 41828092-41837581 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.6;Gastric mucus-secreting cells: 1.8;Late spermatids: 1.1;Squamous epithelial cells: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" HPA005726 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 61: Non-specific - Transcription" Cytosol "HPA005726: AB_1852017" "unprognostic (2.92e-1)" "unprognostic (7.99e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.77e-1)" "unprognostic (2.42e-1)" "unprognostic (8.74e-3)" "unprognostic (3.13e-1)" "unprognostic (7.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 380.1;Squamous epithelial cells: 357.9;Suprabasal keratinocytes: 860.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" KCTD10 "BTBD28, MSTP028" ENSG00000110906 "Potassium channel tetramerization domain containing 10" Q9H3F6 12 109448655-109477359 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 55.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014273 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 69: BICR 18 - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm Cytosol "HPA014273: AB_1852159" "unprognostic (7.21e-3)" "unprognostic (3.04e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.32e-4)" "unprognostic (1.84e-2)" "unprognostic (1.85e-1)" "unprognostic (7.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.45e-1)" "unprognostic (7.72e-2)" "unprognostic (5.76e-2)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.8;Bipolar cells: 3.4;Fibroblasts: 6.5;Horizontal cells: 9.6;Skeletal myocytes: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.5" "Kidney - T-cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952730-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 72.1;Excitatory neurons: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Approved Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 38: Neurons - Neuronal signaling" Microtubules "HPA018135: AB_1859551" "unprognostic (1.67e-1)" "unprognostic (1.65e-3)" "unprognostic (1.14e-2)" "unprognostic (1.46e-2)" "unprognostic (7.34e-2)" "unprognostic (3.52e-2)" "unprognostic (8.71e-3)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (2.66e-2)" "unprognostic (7.68e-2)" "prognostic favorable (3.19e-6)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (7.54e-2)" "unprognostic (7.87e-2)" KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 61.4;Microglial cells: 65.7;Oligodendrocytes: 128.0" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 20.8;skin cancer: 27.6" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" KIF26A "DKFZP434N178, KIAA1236" ENSG00000066735 "Kinesin family member 26A" Q9ULI4 14 104138723-104180894 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 22.0;Endothelial cells: 13.2;Horizontal cells: 6.4;Spermatogonia: 8.4" "Group enriched" "Detected in many" 5 "stomach cancer: 3.8;testis cancer: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 53.4" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046882, HPA060346" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046882: AB_2679856, HPA060346: AB_2684259" "unprognostic (3.01e-1)" "unprognostic (3.20e-1)" "unprognostic (3.95e-1)" "unprognostic (1.77e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-1)" "unprognostic (5.49e-3)" "unprognostic (1.69e-1)" "unprognostic (1.21e-2)" "unprognostic (3.31e-3)" "unprognostic (5.24e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.78e-4)" "unprognostic (7.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.12e-2)" "unprognostic (4.68e-3)" KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 863.2;Glandular and luminal cells: 661.0;Squamous epithelial cells: 1008.3;Suprabasal keratinocytes: 685.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" KLHL42 "Ctb9, KIAA1340, KLHDC5" ENSG00000087448 "Kelch like family member 42" Q9P2K6 12 27780048-27803040 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Peritubular cells: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020979 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA020979: AB_1852559" "unprognostic (4.68e-2)" "unprognostic (1.00e-1)" "unprognostic (3.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (5.46e-2)" "unprognostic (7.38e-3)" "unprognostic (8.82e-2)" "unprognostic (1.50e-2)" "unprognostic (4.92e-2)" "unprognostic (4.89e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 182.4;Microglial cells: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 76.7;Basal respiratory cells: 62.9;Club cells: 93.3;Ionocytes: 72.9;Mucus glandular cells: 63.1;Salivary duct cells: 43.2;Serous glandular cells: 45.8;Suprabasal keratinocytes: 141.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 88.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 7 "NK-cells: 1508.8;T-cells: 767.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 5 "NK-cells: 229.4;T-cells: 105.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" KLRC2 "CD159c, NKG2-C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;lymphoid tissue: 5.8" "Group enriched" "Detected in some" 9 "NK-cells: 77.8;Oligodendrocyte precursor cells: 31.3;T-cells: 59.3" "Cancer enriched" "Detected in single" 8 "glioma: 3.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "gdT-cell: 24.6;NK-cell: 84.5" "Group enriched" "Detected in many" 103 "NK-cells: 84.5;T-cells: 24.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.9" "Adipose visceral - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (9.05e-4)" "unprognostic (2.54e-2)" "unprognostic (3.77e-2)" "unprognostic (2.51e-3)" "unprognostic (2.83e-1)" "unprognostic (9.49e-4)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (2.88e-1)" "unprognostic (4.00e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-9)" "unprognostic (8.10e-2)" "unprognostic (2.34e-1)" "unprognostic (8.93e-2)" "unprognostic (5.31e-3)" KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 5 "NK-cells: 17.4;Oligodendrocyte precursor cells: 34.7;T-cells: 9.4" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cancer enhanced" "Detected in some" "lymphoma: 6.8;thyroid cancer: 5.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Group enriched" "Detected in some" 7 "NK-cells: 25.4;T-cells: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Thyroid - T-cells" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Cell type enriched" "Detected in many" 4 "NK-cells: 1409.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 512.6;memory CD8 T-cell: 217.7;naive CD8 T-cell: 218.7;NK-cell: 737.5" "Group enriched" "Detected in many" 68 "NK-cells: 737.5;T-cells: 512.6" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 7: NK-cells - Immune response regulation" "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 5 "granulocytes: 72.9;NK-cells: 126.9;T-cells: 96.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 390.9;MAIT T-cell: 461.3" "Lineage enriched" "Detected in all" 22 "T-cells: 461.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Group enriched" "Detected in some" 5 "NK-cells: 26.5;T-cells: 41.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Group enriched" "Detected in some" 11 "Leukemia: 10.3;lymphoma: 33.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" KPNA3 "hSRP1, IPOA4, SRP1gamma, SRP4" ENSG00000102753 "Karyopherin subunit alpha 3" O00505 13 49699320-49792682 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Viral penetration into host nucleus, Virus entry into host cell" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 145.4;tongue: 94.2" "Cell type enhanced" "Detected in all" "Early spermatids: 261.9;Late spermatids: 227.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046852, HPA077643" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 13: Non-specific - Nuclear processes" "Cluster 49: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046852: AB_2679840, HPA077643: " "unprognostic (4.20e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (3.69e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.03e-4)" "unprognostic (6.27e-3)" "unprognostic (6.79e-2)" "unprognostic (9.40e-3)" "unprognostic (1.56e-2)" "unprognostic (4.57e-3)" "unprognostic (3.93e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.78e-2)" "unprognostic (7.83e-2)" "unprognostic (5.68e-3)" "unprognostic (4.60e-3)" KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1641.1;Basal respiratory cells: 1142.9;Basal squamous epithelial cells: 8450.6;Squamous epithelial cells: 3518.4" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "cervical cancer: 1216.0;head and neck cancer: 559.1" "Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 4345.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 11.2;testis cancer: 7.1" "Adipose visceral - Neutrophils, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 146.7;granulocytes: 66.1;Hofbauer cells: 191.3;Kupffer cells: 83.7;Macrophages: 128.4;monocytes: 80.2;NK-cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 4.3;Myeloma: 2.5" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Cell type enhanced" "Detected in many" "B-cells: 876.2;dendritic cells: 488.5;granulocytes: 661.3;Hofbauer cells: 1304.4;Kupffer cells: 804.8;Langerhans cells: 566.9;Macrophages: 910.5;monocytes: 1416.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 486.0;lymphoma: 401.3;Myeloma: 125.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 414.0;Inhibitory neurons: 345.8;Oligodendrocyte precursor cells: 249.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 218.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049840, HPA062236" Enhanced Enhanced "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 18: Non-specific - RNA binding" "Cluster 71: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA049840: AB_2680908, HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4605.6;Club cells: 6502.6;Ductal cells: 6093.4;Ionocytes: 7286.2;Mucus glandular cells: 2155.9;Respiratory ciliated cells: 2755.2" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 4 "Bile duct cancer: 2669.0;Gallbladder cancer: 807.0;head and neck cancer: 1263.0;pancreatic cancer: 1708.0" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "epididymis: 14.8;testis: 55.1" "Cell type enriched" "Detected in many" 5 "Late spermatids: 4356.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Group enriched" "Detected in many" 5 "cerebellum: 2.6;medulla oblongata: 2.4;midbrain: 1.2;pons: 2.8;thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 17.8" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 6 "cerebellum: 3.9" HPA045425 Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA045425: AB_10960538" "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (1.88e-2)" "unprognostic (4.20e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.26e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.31e-1)" "unprognostic (5.66e-6)" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-2)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 99.0;Endothelial cells: 72.8;Fibroblasts: 91.7;Hepatocytes: 138.9;Microglial cells: 125.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 65: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 1332.9;Suprabasal keratinocytes: 2929.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 5.4;Esophageal cancer: 2.3;head and neck cancer: 8.1;liver cancer: 2.1" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 11.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 19.5;Kupffer cells: 55.3;Macrophages: 31.3;monocytes: 116.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.8;non-classical monocyte: 169.2" "Lineage enriched" "Detected in many" 5 "monocytes: 169.2" "Not detected" "Not detected" "Liver - Kupffer cells, Lung - Neutrophil_2, Prostate - Macrophages, Stomach - Macrophages" NA NA 94000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (4.52e-2)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (9.46e-3)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.90e-2)" "unprognostic (8.72e-2)" "unprognostic (1.13e-1)" "unprognostic (8.28e-3)" "unprognostic (8.82e-2)" "unprognostic (3.79e-4)" "unprognostic (2.53e-1)" "unprognostic (9.83e-2)" LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 27.5;dendritic cells: 59.3;Hofbauer cells: 29.7;Kupffer cells: 49.5;Macrophages: 65.4;Microglial cells: 30.1;monocytes: 169.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 17 "Leukemia: 1.5;lymphoma: 1.8;Myeloma: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Stomach - Macrophages" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.1;lymphoid tissue: 222.2" "Cell type enhanced" "Detected in many" "B-cells: 398.9;Hofbauer cells: 215.7;Kupffer cells: 171.6;monocytes: 432.0;NK-cells: 429.5;T-cells: 259.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Bone cancer: 60.0;Leukemia: 128.2;lymphoma: 203.6;Myeloma: 65.8;Neuroblastoma: 80.4" "Breast - T-cells, Liver - Kupffer cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (2.90e-3)" "unprognostic (2.89e-3)" "unprognostic (6.34e-2)" "unprognostic (6.53e-2)" "unprognostic (8.72e-2)" "unprognostic (2.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.01e-2)" "unprognostic (1.20e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.36e-11)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (6.08e-2)" LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 280.9;Ductal cells: 110.9;Endothelial cells: 150.2;Exocrine glandular cells: 115.6;Pancreatic endocrine cells: 121.9;Skeletal myocytes: 251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 13 "Excitatory neurons: 862.2;Inhibitory neurons: 568.8;Oligodendrocyte precursor cells: 283.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.1" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Group enriched" "Detected in many" 4 "Astrocytes: 119.3;Oligodendrocyte precursor cells: 131.4" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 727.9;monocytes: 143.5;Oligodendrocyte precursor cells: 246.0;Skeletal myocytes: 250.4" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.2;skin cancer: 3.2" "Breast - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 41: Alveolar cells - Lung function" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 228.7;Ductal cells: 243.5;Exocrine glandular cells: 304.9;Syncytiotrophoblasts: 251.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane, Cell Junctions" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1093.3;dendritic cells: 320.2;Ductal cells: 270.7;Exocrine glandular cells: 811.3;T-cells: 571.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 28.4;lymphoma: 55.6" "Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Skin - Langerhans cells, Thyroid - T-cells" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 105.0;Cardiomyocytes: 89.9;Fibroblasts: 92.5;Leydig cells: 95.6;Mucus glandular cells: 116.8;Peritubular cells: 162.3;Smooth muscle cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1532.4;Extravillous trophoblasts: 5485.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 10 "B-cells: 154.3;Hofbauer cells: 258.4;Kupffer cells: 157.5;Langerhans cells: 123.9;Macrophages: 146.7;Microglial cells: 103.1;monocytes: 146.5;Schwann cells: 66.4" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Group enriched" "Detected in some" 176 "Leukemia: 38.8;lymphoma: 38.4;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 573.0;Squamous epithelial cells: 889.9;Suprabasal keratinocytes: 2645.8;Syncytiotrophoblasts: 1067.1" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 69.6" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Group enriched" "Detected in many" 4 "Early spermatids: 42.3;Late spermatids: 99.0;Syncytiotrophoblasts: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.8" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3373.9;Hofbauer cells: 2648.2;Kupffer cells: 5103.6;Langerhans cells: 5870.5;Macrophages: 4276.5;monocytes: 3002.5;Serous glandular cells: 2631.0" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 1889.9;Leukemia: 787.2" "Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.9;Exocrine glandular cells: 71.1;Ionocytes: 78.1;Mucus glandular cells: 145.9;Respiratory ciliated cells: 73.6;Salivary duct cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1045.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 63: Astrocytes - Nervous system maintenance" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 219.2;Langerhans cells: 134.4;monocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 26.6;dendritic cells: 39.8;Langerhans cells: 29.3;Macrophages: 25.5;Plasma cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 34: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 204.4;Horizontal cells: 185.9;Peritubular cells: 77.1" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skin - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 431.3;retina: 154.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 440.2;Cone photoreceptor cells: 1113.3;Excitatory neurons: 563.9;Horizontal cells: 834.4;Sertoli cells: 508.6;Smooth muscle cells: 468.5" "Cancer enriched" "Detected in all" 5 "glioma: 48.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 114.7;testis cancer: 109.7" "Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Enhanced Cytosol NA NA 180000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: Non-specific - Cilium assembly" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "CAB009792: AB_2137420, HPA022275: AB_1853944" "unprognostic (9.96e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (3.70e-1)" "unprognostic (4.67e-3)" "unprognostic (2.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (7.00e-2)" "unprognostic (4.78e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (8.22e-5)" MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 835.1;Skeletal myocytes: 412.7;Smooth muscle cells: 192.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 43.5;dendritic cells: 52.8;Langerhans cells: 30.6;monocytes: 22.5;Plasma cells: 34.7;Rod photoreceptor cells: 65.2;T-cells: 39.5" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 39 "Leukemia: 16.9;lymphoma: 52.8;Myeloma: 29.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 354.6;Early spermatids: 343.2;Oligodendrocytes: 1417.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol Microtubules "HPA029712: AB_10600303, HPA029713: AB_10601339" "unprognostic (8.68e-3)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.33e-3)" "unprognostic (4.35e-3)" "unprognostic (6.95e-2)" "unprognostic (3.35e-1)" "prognostic favorable (9.22e-4)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (4.61e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.07e-7)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "unprognostic (3.62e-1)" "unprognostic (6.51e-2)" MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 27.2;Cardiomyocytes: 29.4;Cholangiocytes: 26.9;Endometrial stromal cells: 30.1;Fibroblasts: 17.1;Hepatocytes: 58.1" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.0;Rhabdoid: 14.0" "Breast - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "granulocytes: 70.6;Hofbauer cells: 50.4;NK-cells: 303.1;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cancer enhanced" "Detected in many" "Leukemia: 52.8" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 102.8;Macrophages: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 53: Non-specific - mRNA processing" "Cluster 69: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.0;Excitatory neurons: 503.0;Inhibitory neurons: 402.8;Oligodendrocyte precursor cells: 252.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075887 Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 68: Kidney - Mixed function" "Cluster 32: Neurons - Synaptic function" "Golgi apparatus" "HPA075887: " "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" MCTP2 "FLJ11175, FLJ33303" ENSG00000140563 "Multiple C2 and transmembrane domain containing 2" Q6DN12 15 94231538-94483952 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 57.0;NK-cells: 133.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Immune cell enhanced" "Detected in many" "neutrophil: 32.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051176, HPA070541" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Cytosol" "HPA051176: AB_2681373, HPA070541: AB_2686277" "unprognostic (1.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.63e-2)" "unprognostic (7.15e-4)" "unprognostic (3.57e-2)" "unprognostic (2.66e-3)" "unprognostic (3.45e-2)" "unprognostic (3.68e-3)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (5.87e-2)" "unprognostic (4.36e-1)" "unprognostic (1.76e-3)" "unprognostic (9.41e-2)" ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 69.6;Excitatory neurons: 115.3;Inhibitory neurons: 68.9;Muller glia cells: 82.3;Oligodendrocyte precursor cells: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Adipocytes: 117.3;Collecting duct cells: 169.3;Gastric mucus-secreting cells: 117.5;Glandular and luminal cells: 134.0;Microglial cells: 337.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 560.6;Alveolar cells type 1: 955.9;Suprabasal keratinocytes: 363.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 1, Pancreas - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 43: Non-specific - Cell proliferation" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.4;Syncytiotrophoblasts: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 2300.4" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.5" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 38: Neurons - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 12 "Endothelial cells: 255.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cancer enhanced" "Detected in some" "Leukemia: 10.7;ovarian cancer: 6.9;Rhabdoid: 12.9" "Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 427.6;Kupffer cells: 658.3;Langerhans cells: 321.0;Macrophages: 437.6;monocytes: 419.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Cancer enriched" "Detected in some" 12 "Leukemia: 43.6" "Lung - Neutrophil_2, Prostate - Macrophages" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" MOB3B "C9orf35, FLJ13204, MOB1D, MOBKL2B" ENSG00000120162 "MOB kinase activator 3B" Q86TA1 9 27325209-27529814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5;myeloid DC: 2.7;naive B-cell: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 13.2" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (6.96e-3)" "unprognostic (9.60e-2)" "unprognostic (5.10e-3)" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (1.02e-1)" "unprognostic (1.87e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (7.57e-3)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "prognostic favorable (2.33e-10)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.99e-2)" MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 117.7;Cardiomyocytes: 150.4;Excitatory neurons: 210.6;Inhibitory neurons: 264.8;Oligodendrocyte precursor cells: 152.1;Oligodendrocytes: 264.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 32: Neurons - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" MSLNL "C16orf37, MPFL" ENSG00000162006 "Mesothelin like" Q96KJ4 16 769428-783370 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.7;pancreatic cancer: 2.5" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (5.26e-4)" "unprognostic (3.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.38e-2)" "unprognostic (1.54e-1)" "unprognostic (3.73e-3)" "unprognostic (6.50e-2)" "unprognostic (2.09e-1)" "unprognostic (5.36e-2)" "unprognostic (2.16e-1)" MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943293 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 307.9;Proximal tubular cells: 477.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1414.9;neutrophil: 3051.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 3051.8" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Neutrophil_2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153" "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 26.0;Distal enterocytes: 29.2;Gastric mucus-secreting cells: 93.0;Intestinal goblet cells: 25.7;Proximal enterocytes: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 52.3" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 58: Gastric mucus-secreting cells - Digestion" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1949.7" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 965.0" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enriched" "Detected in single" 7 "basal ganglia: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 12.0" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in many" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Myeloma - Humoral immune response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" MUC16 "CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.2;cervix: 15.9;fallopian tube: 5.9;salivary gland: 6.1" "Cell type enhanced" "Detected in some" "Club cells: 89.7;Glandular and luminal cells: 172.4;Ionocytes: 228.5;Respiratory ciliated cells: 242.0;Salivary duct cells: 119.9;Thymic epithelial cells: 437.0" "Cancer enriched" "Detected in many" 4 "ovarian cancer: 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 22.2" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB055172, HPA065600" Enhanced "Secreted in other tissues" NA NA 25000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 5: Bronchus - Unknown function" "CAB055172: AB_2148831, HPA065600: AB_2732736" "unprognostic (8.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.37e-2)" "unprognostic (3.07e-1)" "unprognostic (1.76e-2)" "unprognostic (3.01e-3)" "unprognostic (3.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (2.60e-8)" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "unprognostic (3.68e-3)" MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711016 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 288.7;Cone photoreceptor cells: 172.3;Endometrial stromal cells: 193.4;Muller glia cells: 319.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA044819: AB_10964134, HPA075316: " "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (3.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (8.33e-2)" "unprognostic (5.39e-3)" "unprognostic (4.67e-3)" "unprognostic (6.21e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.80e-5)" MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 1: T-cells - Immune response" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69367726 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;breast: 5.3;esophagus: 9.6;stomach 1: 6.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 36.4;Breast myoepithelial cells: 32.1;Club cells: 12.2;Ductal cells: 12.9;Gastric mucus-secreting cells: 20.9;Paneth cells: 19.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "B-cells: 58.8;Kupffer cells: 72.8;Langerhans cells: 76.6;Macrophages: 64.6;monocytes: 252.2;NK-cells: 164.4;T-cells: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 84.6;lymphoma: 99.5" "Adipose subcutaneous - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" MYOM1 ENSG00000101605 "Myomesin 1" P52179 18 3066807-3219968 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "heart muscle: 412.8;skeletal muscle: 845.6;tongue: 435.6" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 1047.8;Skeletal myocytes: 280.1" "Cancer enhanced" "Detected in many" "liver cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014305, HPA049193" Enhanced NA NA 33000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA014305: AB_1854257, HPA049193: AB_2680670" "unprognostic (2.51e-1)" "unprognostic (2.08e-3)" "unprognostic (2.19e-3)" "unprognostic (8.01e-3)" "unprognostic (8.94e-2)" "unprognostic (4.31e-2)" "unprognostic (9.10e-2)" "unprognostic (1.59e-1)" "unprognostic (9.27e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-1)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (9.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 623.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Liver - Vascular Endothelial cells, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 59: Proximal enterocytes - Transmembrane transport" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" NACAD KIAA0363 ENSG00000136274 "NAC alpha domain containing" O15069 7 45080437-45088969 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.2;pituitary gland: 24.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 19.9;Oligodendrocytes: 21.8;Peritubular cells: 12.2;Sertoli cells: 16.6" "Group enriched" "Detected in many" 7 "glioma: 12.1;testis cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Brain cancer: 6.0;Neuroblastoma: 22.5;testis cancer: 6.7" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020981, HPA079208" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Nucleoplasm "HPA020981: AB_2670549, HPA079208: " "unprognostic (5.54e-6)" "unprognostic (1.89e-1)" "unprognostic (8.55e-4)" "unprognostic (7.06e-3)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.61e-1)" "unprognostic (6.91e-2)" "unprognostic (1.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.17e-2)" "unprognostic (8.17e-3)" "unprognostic (2.76e-2)" "unprognostic (7.72e-3)" "unprognostic (2.72e-3)" "unprognostic (9.22e-2)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.9;Inhibitory neurons: 158.2;Oligodendrocyte precursor cells: 683.5;Oligodendrocytes: 212.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 854.7;Excitatory neurons: 1451.5;Inhibitory neurons: 738.0;Microglial cells: 519.9;Oligodendrocyte precursor cells: 752.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.6" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 263.7;Kupffer cells: 154.3;Langerhans cells: 170.6;Macrophages: 199.3;monocytes: 262.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 63.9;lymphoma: 45.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.0;Alveolar cells type 2: 42.5;Bipolar cells: 64.3;Early spermatids: 157.2;Late spermatids: 266.5" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1939.5;Inhibitory neurons: 1226.2;Oligodendrocyte precursor cells: 695.6;Oligodendrocytes: 417.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 243.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 51: Myeloma - Humoral immune response" "Cluster 11: Non-specific - Transcription" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 56.9;Endometrial stromal cells: 26.7;Fibroblasts: 22.3;Smooth muscle cells: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.6" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 753.1;Oligodendrocyte precursor cells: 581.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.4;esophagus: 2.3;retina: 2.1;skin 1: 3.3" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 69.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 7.7" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 27: Skeletal myocytes - Muscle contraction" "Nuclear bodies" Nucleoplasm "HPA055238: AB_2682752" "unprognostic (2.20e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (9.55e-2)" "unprognostic (2.80e-3)" "unprognostic (1.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-1)" NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 26.0;Fibroblasts: 43.4;Microglial cells: 19.2;Smooth muscle cells: 23.2;Theca cells: 33.9;Thymic epithelial cells: 24.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.2" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Cell type enriched" "Detected in many" 5 "NK-cells: 6101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 26 "Leukemia: 62.9;lymphoma: 64.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in some" "B-cells: 10.6;Erythroid cells: 10.5;NK-cells: 32.2;T-cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Leukemia: 10.5;lymphoma: 13.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.3;Kupffer cells: 19.0;Macrophages: 14.4;Microglial cells: 10.0;monocytes: 30.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "Vesicles, Plasma membrane" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" NLRC5 "CLR16.1, FLJ21709, NOD27" ENSG00000140853 "NLR family CARD domain containing 5" Q86WI3 16 56989485-57083531 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.6;lymphoid tissue: 32.8" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 39.9;NK-cells: 36.3;T-cells: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060405, HPA074724" Supported Centrosome,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol Centrosome "HPA060405: AB_2684277, HPA074724: " "unprognostic (9.66e-2)" "prognostic favorable (9.69e-4)" "unprognostic (1.64e-2)" "unprognostic (1.23e-2)" "unprognostic (3.12e-1)" "unprognostic (9.27e-3)" "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "unprognostic (2.24e-2)" "prognostic favorable (2.30e-4)" "unprognostic (2.69e-1)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.99e-2)" "unprognostic (3.91e-2)" "unprognostic (5.06e-2)" "unprognostic (2.75e-3)" NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 151.5;Proximal tubular cells: 85.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 179.7;Smooth muscle cells: 282.2;Squamous epithelial cells: 76.8;Suprabasal keratinocytes: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 82.7" "Lung - Smooth muscle cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 168.0;Alveolar cells type 2: 89.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 69.2" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 41: Alveolar cells - Lung function" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 34.5;Excitatory neurons: 68.2;Inhibitory neurons: 67.3;Microglial cells: 33.7;Oligodendrocyte precursor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 32: Neurons - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 341.0;Endothelial cells: 171.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 23.3;Breast myoepithelial cells: 28.0;Club cells: 8.3;Cytotrophoblasts: 13.8;Ionocytes: 7.9;Respiratory ciliated cells: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.1" "Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 183.1;Oligodendrocyte precursor cells: 107.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693694-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved NA No "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 8: Non-specific - Transcription" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA044186: AB_10968571, HPA063605: AB_2685058" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (3.14e-1)" "prognostic favorable (2.79e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (6.12e-3)" "unprognostic (6.81e-2)" "prognostic favorable (1.02e-6)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (6.81e-3)" OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 383.4;Hofbauer cells: 218.7;Langerhans cells: 115.9;Macrophages: 149.0;monocytes: 159.4;Syncytiotrophoblasts: 415.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 148.7;head and neck cancer: 80.5" "Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" OR7A5 HTPCR2 ENSG00000188269 "Olfactory receptor family 7 subfamily A member 5" Q15622 19 14826241-14835185 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.9;epididymis: 4.5;parathyroid gland: 7.0" "Cell type enriched" "Detected in single" 9 "Melanocytes: 7.0" "Cancer enriched" "Detected in single" 8 "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate basal glandular cells" HPA053823 Uncertain NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "HPA053823: AB_2682274" "unprognostic (3.26e-4)" "unprognostic (1.44e-1)" "unprognostic (7.46e-2)" "unprognostic (6.19e-3)" "unprognostic (4.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (6.78e-2)" "unprognostic (2.01e-7)" "unprognostic (6.45e-2)" "unprognostic (9.64e-2)" "unprognostic (6.44e-2)" "unprognostic (2.47e-3)" OSBPL3 "KIAA0704, ORP-3, ORP3, OSBP3" ENSG00000070882 "Oxysterol binding protein like 3" Q9H4L5 7 24796540-24981634 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.3;Excitatory neurons: 173.6;Inhibitory neurons: 266.4;Microglial cells: 92.1;Plasma cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - T-cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000691, HPA048401" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 63: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" Cytosol Nucleoli "HPA000691: AB_1854814, HPA048401: AB_2680386" "unprognostic (3.57e-1)" "unprognostic (1.14e-1)" "unprognostic (6.11e-3)" "unprognostic (3.89e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.57e-3)" "unprognostic (4.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (2.34e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.06e-2)" OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.5;testis: 2.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 14.2;Inhibitory neurons: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Enzymes" "Cluster 37: Neurons - Neuronal signaling" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" OVOL2 "bA504H3.3, CHED, CHED1, HOVO2, ZNF339" ENSG00000125850 "Ovo like zinc finger 2" Q9BRP0 20 17956979-18059188 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 7.1;stomach 1: 7.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.9;Spermatocytes: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.9;hippocampal formation: 3.3" HPA038531 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA038531: AB_10673012" "unprognostic (2.85e-2)" "unprognostic (5.13e-2)" "unprognostic (2.41e-2)" "unprognostic (7.35e-2)" "unprognostic (2.14e-1)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (2.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-4)" "unprognostic (4.77e-3)" "unprognostic (2.92e-1)" "unprognostic (2.57e-2)" "unprognostic (3.76e-2)" OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 309.6;Distal tubular cells: 227.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "cervical cancer: 178.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Enzymes" "Cluster 77: Cardiomyocytes - Muscle contraction" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" OXNAD1 MGC15763 ENSG00000154814 "Oxidoreductase NAD binding domain containing 1" Q96HP4 3 16265160-16350299 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.1;Inhibitory neurons: 61.5;T-cells: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 81.0" "Lineage enriched" "Detected in all" 4 "T-cells: 81.0" "Low cancer specificity" "Detected in all" "Colon - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036830, HPA059160" Approved Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 5: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA036830: AB_2675338, HPA059160: AB_2683936" "unprognostic (4.49e-2)" "unprognostic (7.41e-3)" "unprognostic (2.71e-3)" "unprognostic (2.38e-3)" "unprognostic (4.65e-2)" "unprognostic (3.23e-2)" "unprognostic (1.46e-1)" "unprognostic (2.31e-2)" "unprognostic (1.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.46e-1)" "unprognostic (8.08e-2)" "prognostic favorable (1.00e-7)" "unprognostic (2.22e-2)" "unprognostic (1.03e-1)" "unprognostic (6.95e-3)" "prognostic favorable (7.63e-4)" P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.7;skeletal muscle: 50.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.5;Proximal enterocytes: 15.3;Squamous epithelial cells: 15.6;Syncytiotrophoblasts: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.6" "Group enriched" "Detected in many" 12 "granulocytes: 57.6;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 321.4;Distal enterocytes: 166.2;monocytes: 243.3;Proximal enterocytes: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells, Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "B-cells: 86.0;granulocytes: 13.0;NK-cells: 41.7;T-cells: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 18.2;lymphoma: 18.0" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 63.0;dendritic cells: 79.8;Hofbauer cells: 90.3;Kupffer cells: 80.9;Langerhans cells: 62.2;Macrophages: 87.0;monocytes: 124.2;Schwann cells: 66.9;T-cells: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 5 "Leukemia: 55.6" "Adipose subcutaneous - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 172.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 75.0" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 72.3" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 77: Cardiomyocytes - Muscle contraction" "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: AB_2685663, HPA066960: AB_2685755, HPA069079: AB_2686079" "unprognostic (1.81e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (7.60e-2)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-3)" "unprognostic (2.99e-2)" "prognostic favorable (1.47e-5)" "unprognostic (3.05e-3)" "unprognostic (6.72e-3)" "unprognostic (2.21e-2)" "unprognostic (2.43e-1)" PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.8;Cardiomyocytes: 22.4;NK-cells: 39.6;T-cells: 27.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cancer enhanced" "Detected in some" "lymphoma: 6.4;Myeloma: 12.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.2;Early spermatids: 10.8;Peritubular cells: 7.7;Skeletal myocytes: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.2" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.3;Cholangiocytes: 7.7;Endometrial stromal cells: 8.4;Fibroblasts: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 52: Endometrial stromal cells - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.8;Endometrial stromal cells: 8.3;Fibroblasts: 9.3;Horizontal cells: 6.4;Peritubular cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear membrane" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Early spermatids: 40.8;Late spermatids: 29.5;Spermatocytes: 20.8" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" PCDHB9 "PCDH-BETA9, PCDH3H" ENSG00000177839 "Protocadherin beta 9" Q9Y5E1 5 141187127-141191541 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Bipolar cells: 17.3;Horizontal cells: 12.8" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.6" "Lung - Fibroblast_1, Prostate - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" "HPA013445: AB_1855054" "unprognostic (1.85e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-1)" "unprognostic (8.97e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.12e-1)" "unprognostic (6.78e-3)" "unprognostic (1.34e-2)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (1.86e-4)" "unprognostic (1.71e-1)" "unprognostic (9.80e-2)" "unprognostic (1.17e-1)" "unprognostic (8.01e-2)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.3;Bipolar cells: 7.6;Fibroblasts: 11.8;Serous glandular cells: 8.6;Skeletal myocytes: 7.9;Thymic epithelial cells: 11.0" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.5;Inhibitory neurons: 33.2;Squamous epithelial cells: 27.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Sebaceous gland cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 35: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 183.8;Inhibitory neurons: 79.5;Oligodendrocyte precursor cells: 143.0;Proximal enterocytes: 151.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 2447.1;neutrophil: 626.3" "Lineage enriched" "Detected in all" 18 "granulocytes: 2447.1" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 290000 "Cluster 41: Basophils - Cellular respiration" "Cluster 45: Intestine - Brush border" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2;retina: 12.1;testis: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 22.8;Early spermatids: 30.1;Late spermatids: 90.8;Muller glia cells: 25.3;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 39.5" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.4;testis cancer: 7.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 51: Late spermatids - Spermatogenesis" "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1011.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 48.0" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Cell type enhanced" "Detected in many" "Adipocytes: 114.4;Endothelial cells: 72.1;Excitatory neurons: 69.1;Inhibitory neurons: 34.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cancer enriched" "Detected in many" 4 "cervical cancer: 104.1" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 56: Neurons - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 139.1;Leydig cells: 161.7;Peritubular cells: 206.1;Sertoli cells: 522.4;Smooth muscle cells: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 30.9;testis cancer: 38.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3404.2;Squamous epithelial cells: 3820.8;Suprabasal keratinocytes: 7537.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" PEX11G ENSG00000104883 "Peroxisomal biogenesis factor 11 gamma" Q96HA9 19 7476875-7497449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.4;testis: 29.0" "Cell type enhanced" "Detected in many" "Early spermatids: 88.9;Hepatocytes: 44.2;Late spermatids: 73.7;Proximal enterocytes: 37.5;Proximal tubular cells: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA069817 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: Non-specific - Cilium assembly" "Cluster 49: Early spermatids - Spermatogenesis" "HPA069817: AB_2686207" "unprognostic (2.26e-2)" "unprognostic (6.44e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.60e-4)" "unprognostic (1.01e-1)" "unprognostic (4.09e-3)" "prognostic favorable (3.27e-4)" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" "unprognostic (2.32e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.83e-9)" "unprognostic (1.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.19e-2)" PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 5846.0;Hofbauer cells: 4288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 49: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "B-cells: 24.2;dendritic cells: 34.7;Kupffer cells: 25.1;Macrophages: 24.1;Microglial cells: 28.3;monocytes: 22.0;NK-cells: 28.9;T-cells: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 58.7;lymphoma: 54.5" "Prostate - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 188.9;Endothelial cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 8.7;Spermatogonia: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.3;Leukemia: 11.4" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 20: Airway & Pancreas - Proteolysis" "Nucleoplasm, Mitochondria" "HPA036587: AB_2732473, HPA036588: AB_10673502, HPA057508: AB_2683452" "unprognostic (1.43e-1)" "unprognostic (9.46e-2)" "unprognostic (2.59e-3)" "unprognostic (2.22e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-3)" "unprognostic (1.96e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-4)" "unprognostic (6.89e-2)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 315.6;Squamous epithelial cells: 258.3;Suprabasal keratinocytes: 748.6" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 171.3;head and neck cancer: 98.1" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.3;Distal enterocytes: 250.2;Extravillous trophoblasts: 189.3;Proximal enterocytes: 184.4;Suprabasal keratinocytes: 357.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 53.8;Hofbauer cells: 332.3;Macrophages: 103.3;Prostatic glandular cells: 60.2" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cancer enriched" "Detected in some" 8 "prostate cancer: 16.5" "Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 69: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 423.9;Granulosa cells: 500.2;Proximal tubular cells: 667.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 17: Granulosa cells - Transcription regulation" Mitochondria Cytosol "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1487.4;Distal enterocytes: 1382.1;Extravillous trophoblasts: 711.2;monocytes: 425.9;NK-cells: 741.1" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - Colon enterocytes, Prostate - T-cells, Stomach - Gastric mucous cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 50: Enterocytes - Absorption" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.7;Kupffer cells: 40.2;Macrophages: 42.0;Microglial cells: 38.3;monocytes: 57.5;NK-cells: 23.1;Schwann cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.3" "Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "B-cells: 84.2;Microglial cells: 93.0;NK-cells: 44.5;Plasma cells: 97.6" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 34.8;lymphoma: 123.9;Myeloma: 32.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Intercalated cells, Liver - Hepatocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" PLCL2 "KIAA1092, PLCE2" ENSG00000154822 "Phospholipase C like 2" Q9UPR0 3 16802651-17090604 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 27.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 209.5;Extravillous trophoblasts: 91.5;Inhibitory neurons: 159.7;Microglial cells: 121.3;Oligodendrocyte precursor cells: 116.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 9.6;Myeloma: 8.8" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047616, HPA061728" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA047616: AB_2680105, HPA061728: " "unprognostic (2.95e-2)" "unprognostic (8.09e-2)" "unprognostic (3.96e-2)" "unprognostic (6.35e-2)" "unprognostic (1.59e-1)" "unprognostic (3.83e-3)" "unprognostic (1.83e-1)" "unprognostic (9.31e-2)" "unprognostic (3.22e-2)" "unprognostic (8.72e-2)" "unprognostic (5.93e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.98e-10)" "unprognostic (2.01e-1)" "unprognostic (1.78e-1)" "unprognostic (2.70e-1)" "unprognostic (9.97e-2)" PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 490.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 91.2;Basal respiratory cells: 61.5;Exocrine glandular cells: 55.5;Intestinal goblet cells: 58.7;Langerhans cells: 67.0;Suprabasal keratinocytes: 58.9;Theca cells: 72.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cancer enhanced" "Detected in many" "Bile duct cancer: 120.6" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 46: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 107.5;Gastric mucus-secreting cells: 47.1;Microglial cells: 47.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 2.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: AB_10671746, HPA066103: AB_2732738" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (4.30e-2)" "unprognostic (2.51e-2)" "unprognostic (6.95e-3)" "unprognostic (2.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (3.13e-2)" "prognostic favorable (1.89e-15)" "unprognostic (9.74e-2)" "unprognostic (1.17e-2)" "unprognostic (4.81e-1)" "unprognostic (2.65e-2)" PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Ductal cells: 20.2;Exocrine glandular cells: 23.2;Squamous epithelial cells: 41.9;Suprabasal keratinocytes: 72.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 24.0" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 362.5;Fibroblasts: 403.1;Leydig cells: 881.4;Peritubular cells: 311.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 64.2" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102798976 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.9" "Group enriched" "Detected in many" 5 "NK-cells: 3.9;T-cells: 2.4" "Cancer enhanced" "Detected in all" "Kidney cancer: 67.6" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 44000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 62.9;Excitatory neurons: 117.7;Inhibitory neurons: 45.6;Oligodendrocyte precursor cells: 47.7;Oligodendrocytes: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Leukemia: 16.3;lymphoma: 37.0;Myeloma: 27.4;Neuroblastoma: 15.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.7;prostate: 13.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.0;Early spermatids: 19.7;Enteroendocrine cells: 24.0;Intestinal goblet cells: 13.5;Late spermatids: 62.1;Paneth cells: 15.3;Prostatic glandular cells: 44.8;Undifferentiated cells: 31.9" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 17.7;prostate cancer: 41.8" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "Langerhans cells: 238.5;NK-cells: 290.6;Plasma cells: 690.4;T-cells: 215.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cancer enriched" "Detected in many" 4 "Myeloma: 92.7" "Colon - T-cells, Prostate - T-cells" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 695.3;Microglial cells: 117.7;Oligodendrocyte precursor cells: 404.3;Oligodendrocytes: 209.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 6.8;ovarian cancer: 3.3;Uterine cancer: 4.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" PRICKLE3 LMO6 ENSG00000012211 "Prickle planar cell polarity protein 3" O43900 X 49174802-49186528 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 58.3;Late spermatids: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA000998 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 48: Non-specific - RNA binding" "Cluster 51: Late spermatids - Spermatogenesis" "HPA000998: AB_1079258" "unprognostic (9.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.97e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-2)" "unprognostic (3.78e-2)" "unprognostic (1.14e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (2.28e-3)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.84e-5)" PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556124-151877125 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 143.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 205.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.46e-2)" "unprognostic (9.29e-2)" "unprognostic (1.76e-1)" "unprognostic (4.33e-3)" "unprognostic (7.13e-2)" "unprognostic (8.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.80e-1)" "unprognostic (3.61e-2)" "unprognostic (4.52e-1)" PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.1;NK-cells: 34.2;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 71.0;Skeletal myocytes: 34.6;T-cells: 35.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cancer enriched" "Detected in many" 5 "Leukemia: 17.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - Alveolar cells type 2, Prostate - T-cells, Skeletal muscle - Skeletal myocytes, Skin - T-cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 1: T-cells - Immune response" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 723.8;Syncytiotrophoblasts: 1296.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 39: Non-specific - Unknown function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: Non-specific - Nuclear processes" "Cluster 16: Non-specific - RNA binding" Nucleoplasm Cytosol "CAB034225: AB_1564157, HPA055687: AB_2682886" "unprognostic (6.75e-3)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (7.06e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-3)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (9.31e-3)" "unprognostic (2.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 122.4;Basal squamous epithelial cells: 127.9;Squamous epithelial cells: 148.1;Suprabasal keratinocytes: 189.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 292.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 64: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" PSMC3 "TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Deafness, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: AB_1079706" "unprognostic (2.01e-2)" "unprognostic (5.08e-3)" "unprognostic (9.43e-2)" "unprognostic (8.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.71e-2)" "unprognostic (8.99e-3)" "unprognostic (1.63e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 54.7;Kupffer cells: 54.0;Langerhans cells: 38.0;Macrophages: 41.3;monocytes: 32.9;NK-cells: 72.7;T-cells: 64.7;Theca cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 13.3;lymphoma: 11.8" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB004076, HPA031335, CAB080153, CAB080155, CAB080157" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Nucleoplasm "CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity, Lipid metabolism" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Cell type enhanced" "Detected in many" "B-cells: 57.0;granulocytes: 38.6;NK-cells: 204.4;T-cells: 143.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 15.4;lymphoma: 22.3;Myeloma: 12.6" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 63.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 26.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "HPA038343: AB_10671741, HPA046728: AB_2679776" "prognostic unfavorable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 43.8;granulocytes: 71.9;NK-cells: 133.5;T-cells: 129.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Group enriched" "Detected in some" 41 "Leukemia: 72.3;lymphoma: 27.8;Myeloma: 22.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Testis - Sertoli cells, Thyroid - T-cells" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 163.5;Microglial cells: 184.3;Oligodendrocyte precursor cells: 229.6;Oligodendrocytes: 158.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" NA NA 670000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 12: Non-specific - Chromatin organization" "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 72.0" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" PYHIN1 "IFIX, MGC23885" ENSG00000163564 "Pyrin and HIN domain family member 1" Q6K0P9 1 158930796-158977059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 23.1" "Group enriched" "Detected in some" 12 "NK-cells: 289.6;T-cells: 96.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "gdT-cell: 97.3;MAIT T-cell: 56.3;memory CD4 T-cell: 40.8;memory CD8 T-cell: 74.7;naive CD8 T-cell: 45.1;NK-cell: 36.8;T-reg: 67.3" "Group enriched" "Detected in many" 5 "NK-cells: 36.8;T-cells: 97.3" "Cancer enriched" "Detected in some" 5 "lymphoma: 13.8" "Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "HPA051224, HPA055373" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoli Nucleoplasm "HPA051224: AB_2681394, HPA055373: " "unprognostic (1.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.93e-3)" "unprognostic (2.64e-3)" "unprognostic (3.99e-2)" "unprognostic (3.57e-3)" "unprognostic (2.44e-3)" "unprognostic (2.10e-2)" "unprognostic (1.52e-1)" "unprognostic (1.47e-3)" "unprognostic (3.94e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-6)" "unprognostic (1.83e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-2)" "unprognostic (4.45e-3)" QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Extravillous trophoblasts: 1885.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 54: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: BEWO - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" RAB15 ENSG00000139998 "RAB15, member RAS oncogene family" P59190 14 64945814-64973226 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 34.9;Excitatory neurons: 50.5;Intestinal goblet cells: 32.4" "Cancer enhanced" "Detected in all" "testis cancer: 83.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.9" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041177 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Centriolar satellite" "HPA041177: AB_10794547" "unprognostic (9.80e-2)" "unprognostic (1.42e-2)" "unprognostic (1.53e-1)" "unprognostic (4.94e-2)" "unprognostic (6.29e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (7.14e-2)" "unprognostic (3.12e-1)" "unprognostic (4.25e-2)" "unprognostic (2.79e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-2)" "unprognostic (2.82e-2)" RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 21.3;Peritubular cells: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Supported "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Cytosol" Centrosome "HPA029135: AB_10602070, HPA029136: AB_10601794" "unprognostic (8.78e-2)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.55e-2)" "unprognostic (5.33e-3)" "unprognostic (6.41e-2)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "unprognostic (9.12e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-3)" RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.6;skin 1: 44.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.9;Basal respiratory cells: 69.0;Cytotrophoblasts: 95.4;Melanocytes: 191.6;Suprabasal keratinocytes: 113.8" "Cancer enhanced" "Detected in all" "melanoma: 73.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 85.9;skin cancer: 97.9" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.1" HPA071701 Uncertain "Nuclear bodies,Mitochondria" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear bodies, Mitochondria" "HPA071701: " "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (2.66e-2)" "unprognostic (1.36e-2)" "unprognostic (7.95e-2)" "unprognostic (3.96e-4)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "unprognostic (9.34e-2)" "unprognostic (1.00e-2)" "unprognostic (8.23e-2)" "prognostic favorable (8.26e-4)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 322.2;granulocytes: 501.6;monocytes: 297.7;NK-cells: 519.2;Plasma cells: 299.5;T-cells: 411.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 357.2;lymphoma: 336.6" "Breast - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 62: Granulocytes - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 41.4;Respiratory ciliated cells: 20.6;Suprabasal keratinocytes: 40.3;Thymic epithelial cells: 52.0" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 23.2" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" RALGDS "RalGEF, RGDS, RGF" ENSG00000160271 "Ral guanine nucleotide dissociation stimulator" Q12967 9 133097720-133149334 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 24.0;MAIT T-cell: 9.7;memory CD4 T-cell: 10.9;memory CD8 T-cell: 17.6;naive CD8 T-cell: 9.1;NK-cell: 9.0;T-reg: 20.8" "Group enriched" "Detected in many" 7 "NK-cells: 9.0;T-cells: 24.0" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "HPA025961, CAB032582" Approved Uncertain Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB032582: AB_2238105, HPA025961: AB_2671795" "unprognostic (1.01e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.35e-2)" "unprognostic (7.92e-3)" "unprognostic (8.20e-2)" "unprognostic (7.95e-2)" "unprognostic (5.09e-2)" "unprognostic (2.20e-1)" "unprognostic (8.91e-2)" "unprognostic (2.88e-1)" "unprognostic (2.69e-3)" "unprognostic (5.03e-2)" "unprognostic (9.54e-3)" "unprognostic (5.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 53.3;Excitatory neurons: 80.7;Horizontal cells: 96.1;Intestinal goblet cells: 122.3;Oligodendrocyte precursor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.7;pancreas: 37.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 58.7;Excitatory neurons: 130.7;Inhibitory neurons: 66.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 12 "amygdala: 10.6;basal ganglia: 13.6;cerebral cortex: 11.0;hippocampal formation: 17.9;white matter: 11.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022148, HPA022896" Approved Supported "Nuclear membrane,Cytosol" NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "Nuclear membrane, Cytosol" "HPA022148: AB_1849474, HPA022896: AB_1849476" "unprognostic (1.85e-3)" "unprognostic (1.02e-2)" "unprognostic (8.92e-2)" "unprognostic (5.39e-1)" "unprognostic (4.04e-2)" "unprognostic (3.92e-1)" "unprognostic (6.52e-5)" "unprognostic (1.18e-2)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.66e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.36e-6)" "unprognostic (3.44e-2)" "unprognostic (6.38e-2)" "unprognostic (9.33e-2)" "unprognostic (7.50e-2)" RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 434.8;Inhibitory neurons: 407.0;Microglial cells: 138.6;Oligodendrocyte precursor cells: 290.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.1" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 37: Neurons - Neuronal signaling" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 65.1;Distal enterocytes: 80.1;Squamous epithelial cells: 102.3;Suprabasal keratinocytes: 122.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Kidney - Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 59.8;salivary gland: 28.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.5;Excitatory neurons: 13.7;Gastric mucus-secreting cells: 45.9;Oligodendrocytes: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 12.1" "Colon - Colon enterocytes, Liver - Cholangiocyte, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.5;dendritic cells: 22.6;granulocytes: 24.5;monocytes: 31.6;NK-cells: 90.9;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Leukemia: 24.3;lymphoma: 22.6;Myeloma: 28.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 218.0;Inhibitory neurons: 398.2;Microglial cells: 86.7;Oligodendrocytes: 373.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.2;Muller glia cells: 74.0;NK-cells: 109.5;T-cells: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Cancer enhanced" "Detected in many" "lymphoma: 19.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 1: T-cells - Immune response" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" RASL10A RRP22 ENSG00000100276 "RAS like family 10 member A" Q92737 22 29312933-29319679 "Enzymes, Predicted intracellular proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 28.7" "Cell type enhanced" "Detected in some" "Astrocytes: 17.4;Breast glandular cells: 41.9;Breast myoepithelial cells: 50.2;Excitatory neurons: 34.6;Rod photoreceptor cells: 19.3" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 3.4;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 6 "amygdala: 33.7;basal ganglia: 16.7;cerebral cortex: 36.0;hippocampal formation: 26.3;white matter: 15.3" "Group enriched" "Detected in many" 4 "cerebral cortex: 35.6;hippocampal formation: 27.8" HPA056169 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "HPA056169: AB_2683053" "unprognostic (1.94e-1)" "unprognostic (2.51e-4)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (7.99e-2)" "unprognostic (9.42e-2)" "unprognostic (1.61e-2)" "unprognostic (5.00e-4)" "unprognostic (2.44e-1)" "unprognostic (7.00e-4)" "unprognostic (3.12e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (3.61e-3)" RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 21.8;Cardiomyocytes: 23.8;Muller glia cells: 21.2;Peritubular cells: 59.2;Schwann cells: 19.6;Sertoli cells: 55.3;Smooth muscle cells: 68.9" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 6.9;testis cancer: 17.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" RBM24 "dJ259A10.1, FLJ30829, RNPC6" ENSG00000112183 "RNA binding motif protein 24" Q9BX46 6 17281361-17293871 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 142.1;skeletal muscle: 313.0;tongue: 105.7" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 238.0;Skeletal myocytes: 253.4" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA066927, HPA067231" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA066927: AB_2685750, HPA067231: AB_2685808" "unprognostic (9.05e-3)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-3)" "unprognostic (1.53e-1)" "unprognostic (4.54e-4)" "unprognostic (3.34e-2)" "unprognostic (1.33e-2)" "unprognostic (2.97e-3)" "unprognostic (3.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-2)" "unprognostic (3.06e-2)" "unprognostic (1.08e-2)" "unprognostic (2.33e-4)" RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Cell type enhanced" "Detected in many" "Ductal cells: 937.0;Endometrial stromal cells: 1067.0;Exocrine glandular cells: 869.9;Granulosa cells: 5685.6;Theca cells: 2489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 282.2" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Leydig cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: DU4475 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 55.3;Fibroblasts: 112.2;Leydig cells: 38.9;Pancreatic endocrine cells: 60.1;Peritubular cells: 43.0;Smooth muscle cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cancer enhanced" "Detected in all" "Bone cancer: 129.1;Sarcoma: 126.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.3;Inhibitory neurons: 94.9;Microglial cells: 83.9;Oligodendrocyte precursor cells: 106.9;Oligodendrocytes: 165.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 129.4;Excitatory neurons: 173.7;Inhibitory neurons: 138.7;Macrophages: 81.6;Microglial cells: 74.8;Oligodendrocytes: 174.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 164.4" "Group enriched" "Detected in some" 6 "Early spermatids: 23.7;monocytes: 27.5;NK-cells: 35.0;T-cells: 45.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 393.6;neutrophil: 516.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 516.3" "Cancer enhanced" "Detected in many" "Leukemia: 12.0" "Lung - Neutrophil_2, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Centrosome "HPA035979: AB_10673227" "unprognostic (1.48e-4)" "unprognostic (2.75e-4)" "unprognostic (4.44e-2)" "unprognostic (1.11e-4)" "unprognostic (3.10e-1)" "unprognostic (2.93e-4)" "unprognostic (4.92e-2)" "unprognostic (2.06e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-1)" "unprognostic (4.25e-2)" "unprognostic (3.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-2)" "unprognostic (1.26e-1)" "unprognostic (1.07e-3)" RGS18 RGS13 ENSG00000150681 "Regulator of G protein signaling 18" Q9NS28 1 192158462-192185815 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.2;lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "dendritic cells: 36.1;Kupffer cells: 95.2;Langerhans cells: 37.1;Macrophages: 65.8;monocytes: 148.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 353.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 353.1" "Cancer enriched" "Detected in some" 4 "Leukemia: 18.1" "Lung - Neutrophil_2, Prostate - Macrophages, Testis - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028727, HPA045780" Uncertain Approved "Golgi apparatus" NA NA 340000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 4: Platelets - Platelet activation" "Golgi apparatus" "HPA028727: AB_2797219, HPA045780: AB_10962728" "unprognostic (3.09e-2)" "unprognostic (4.32e-2)" "unprognostic (8.66e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.48e-1)" "unprognostic (2.18e-2)" "unprognostic (2.58e-1)" "unprognostic (1.87e-1)" "unprognostic (3.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.30e-3)" "unprognostic (8.21e-3)" "unprognostic (2.81e-4)" "unprognostic (1.73e-2)" "unprognostic (9.91e-2)" RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 496.8;Late spermatids: 1667.0" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 6: Late spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 74.4;Club cells: 47.8;Distal enterocytes: 54.2;Ionocytes: 52.0;Oligodendrocytes: 50.9;Suprabasal keratinocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Group enriched" "Detected in many" 5 "Squamous epithelial cells: 1909.7;Suprabasal keratinocytes: 4570.8" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 20.4;head and neck cancer: 42.3" "Kidney - Intercalated cells, Prostate - Urothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Group enriched" "Detected in many" 6 "B-cells: 234.2;granulocytes: 305.0;NK-cells: 110.3;Plasma cells: 137.4;T-cells: 216.5" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Bone cancer: 37.0;Leukemia: 54.2;lymphoma: 77.1;Myeloma: 49.0" "Adipose visceral - T-cells, Liver - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.5;Astrocytes: 170.5;Endothelial cells: 70.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;skin cancer: 36.2" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 72.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 56.4;Endometrial ciliated cells: 73.6;Gastric mucus-secreting cells: 56.6;Glandular and luminal cells: 169.7;Squamous epithelial cells: 69.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA030942 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.7;Cholangiocytes: 9.6;Ductal cells: 4.7;Suprabasal keratinocytes: 2.7;Syncytiotrophoblasts: 13.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;head and neck cancer: 11.2" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "monocytes: 80.6;NK-cells: 154.4;T-cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.6;Breast myoepithelial cells: 33.9;Club cells: 76.3;Ionocytes: 106.6;Suprabasal keratinocytes: 39.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 305.1;Inhibitory neurons: 1478.5;Oligodendrocyte precursor cells: 333.6;Oligodendrocytes: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 276.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" RTP5 "C2orf85, CXXC11, FLJ33590, Z3CXXC5" ENSG00000188011 "Receptor transporter protein 5 (putative)" Q14D33 2 241869600-241873823 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "brain: 32.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 4.0;Late spermatids: 6.1;Oligodendrocyte precursor cells: 16.8" "Cancer enriched" "Detected in single" 10 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - T-cells" "Low region specificity" "Detected in all" HPA050902 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA050902: AB_2681268" "unprognostic (3.26e-2)" "unprognostic (5.38e-4)" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "unprognostic (9.40e-4)" "unprognostic (8.68e-3)" "unprognostic (2.04e-1)" "unprognostic (6.34e-4)" "unprognostic (3.30e-1)" "unprognostic (9.01e-3)" "unprognostic (3.91e-1)" "unprognostic (9.08e-8)" "unprognostic (1.81e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.72e-2)" RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.6;Mucus glandular cells: 179.0;Salivary duct cells: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cancer enhanced" "Detected in many" "Leukemia: 98.3" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 147.2;NK-cells: 443.6;T-cells: 232.6" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bone cancer: 17.8;Leukemia: 19.3;lymphoma: 47.9;Myeloma: 36.7;skin cancer: 28.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2185.0;Distal enterocytes: 1714.4;Proximal enterocytes: 1543.9;Squamous epithelial cells: 3706.1;Suprabasal keratinocytes: 5461.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 976.3" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 973.9;Squamous epithelial cells: 1202.5;Suprabasal keratinocytes: 2430.8;Theca cells: 1030.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1882.4;Extravillous trophoblasts: 868.6;Gastric mucus-secreting cells: 2002.0;Ionocytes: 1013.7;Syncytiotrophoblasts: 2962.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Gastric mucous cells, Testis - Late spermatids, Thyroid - Neutrophils" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Enzymes" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.6;lymphoid tissue: 61.1" "Cell type enhanced" "Detected in many" "B-cells: 64.7;dendritic cells: 40.5;Hofbauer cells: 37.9;Kupffer cells: 35.7;monocytes: 72.1;NK-cells: 119.6;T-cells: 75.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 11 "Leukemia: 45.1;lymphoma: 36.4;Myeloma: 25.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Prostate - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 7: NK-cells - Immune response regulation" Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23328826-23433740 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.3;Excitatory neurons: 85.0;Inhibitory neurons: 106.0;Mucus glandular cells: 62.6;Oligodendrocyte precursor cells: 73.2;Oligodendrocytes: 104.8;Skeletal myocytes: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 165.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA 37000 "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 4: Non-specific - Transcription" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Cytosol" "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.27e-1)" SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 5 "NK-cells: 253.7;T-cells: 72.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Pancreas - Alpha cells, Prostate - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 7: NK-cells - Immune response regulation" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.1" "Cell type enhanced" "Detected in many" "NK-cells: 120.0;Paneth cells: 77.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 28.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 44.7" "Prostate - T-cells" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 1: T-cells - Immune response" Cytosol Vesicles "HPA021318: AB_2183383, HPA021319: AB_1856554" "unprognostic (3.66e-2)" "unprognostic (5.35e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (8.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (4.76e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (8.31e-5)" "unprognostic (6.00e-2)" "prognostic unfavorable (8.40e-7)" "unprognostic (5.91e-2)" "unprognostic (1.37e-2)" "unprognostic (2.18e-2)" "unprognostic (3.64e-1)" SBDS "CGI-97, FLJ10917, SDS, SWDS" ENSG00000126524 "SBDS ribosome maturation factor" Q9Y3A5 7 66987680-66995587 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 2157.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028891 Approved Supported Nucleoplasm,Cytosol NA NA 190000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA028891: AB_10601500" "prognostic unfavorable (1.49e-4)" "unprognostic (1.87e-2)" "unprognostic (5.73e-2)" "unprognostic (1.71e-3)" "unprognostic (8.06e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.07e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (6.99e-2)" "unprognostic (7.84e-3)" "unprognostic (4.59e-1)" "unprognostic (1.04e-2)" "unprognostic (9.38e-3)" "unprognostic (1.83e-1)" "unprognostic (2.30e-1)" "unprognostic (5.06e-3)" SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 231.2;Basal prostatic cells: 71.1;Collecting duct cells: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 80.1" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 63: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 3079.0" "Cell type enhanced" "Detected in some" "Club cells: 66462.1;Ionocytes: 25571.0;Respiratory ciliated cells: 11627.8" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "Esophageal cancer: 166.4;Gallbladder cancer: 108.3;head and neck cancer: 60.7;pancreatic cancer: 91.7" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" NA NA 13000000 "Cluster 19: Lung - Lung function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Group enriched" "Detected in many" 7 "B-cells: 78.9;Hofbauer cells: 42.8;Kupffer cells: 89.4;Macrophages: 63.9;monocytes: 119.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cancer enhanced" "Detected in many" "lymphoma: 15.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 226.5;Alveolar cells type 2: 187.3;Distal enterocytes: 120.6;Glandular and luminal cells: 185.6;Intestinal goblet cells: 186.4;Salivary duct cells: 181.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 94.7;Club cells: 57.7;Distal enterocytes: 198.1;Ionocytes: 49.4;Salivary duct cells: 78.1;Suprabasal keratinocytes: 51.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 29.9;Sarcoma: 37.7" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 27: TE 441.T - Unknown function" "Cluster 50: Enterocytes - Absorption" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.0;Club cells: 26.4;Collecting duct cells: 41.4;Gastric mucus-secreting cells: 14.9;Glandular and luminal cells: 16.7;Ionocytes: 17.9;Salivary duct cells: 27.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bone cancer: 15.9" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 14: Bone cancer - Transcription" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7;choroid plexus: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 44.9;Melanocytes: 50.5;Muller glia cells: 138.4;Oligodendrocyte precursor cells: 97.7;Sertoli cells: 94.0" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Brain cancer: 2.2;skin cancer: 3.0" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" NA NA 240000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 68: Muller glia cells - Visual perception" "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 68: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 6.0;Horizontal cells: 8.3;Rod photoreceptor cells: 10.6;Smooth muscle cells: 6.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 12.4;testis cancer: 10.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 215.5;Alveolar cells type 2: 457.8;Basal respiratory cells: 335.5;Ionocytes: 292.4;Suprabasal keratinocytes: 237.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 11.2;Alveolar cells type 2: 8.8;Cholangiocytes: 9.6;Collecting duct cells: 13.8;Ductal cells: 6.7;granulocytes: 6.3;Muller glia cells: 15.5" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney cancer: 25.0" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Sebaceous gland cells, Testis - Sertoli cells" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065985, HPA069974" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "Golgi apparatus" "HPA065985: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 920.7;Smooth muscle cells: 623.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "dendritic cells: 122.3;Exocrine glandular cells: 58.5;Extravillous trophoblasts: 64.4;Granulosa cells: 65.0;Rod photoreceptor cells: 52.5;Syncytiotrophoblasts: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Low cancer specificity" "Detected in many" "Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in many" "B-cells: 98.3;NK-cells: 87.5;T-cells: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 58 "Leukemia: 27.5;lymphoma: 32.6;Myeloma: 19.8" "Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 304.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 166.4;Cone photoreceptor cells: 579.0;Horizontal cells: 571.0;Oligodendrocytes: 154.4;Rod photoreceptor cells: 324.2" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 11.1" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 54.0;Basal respiratory cells: 353.0;Club cells: 55.7;Ductal cells: 126.9;Extravillous trophoblasts: 91.8;Ionocytes: 115.2" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 47.9" "Prostate - Urothelial cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 21.4;Proximal tubular cells: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 8 "NK-cells: 146.9;T-cells: 98.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Cancer enriched" "Detected in some" 4 "Leukemia: 38.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.5" "Cell type enhanced" "Detected in many" "Ionocytes: 66.9;Paneth cells: 68.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" SH3BP5 Sab ENSG00000131370 "SH3 domain binding protein 5" O60239 3 15254353-15341368 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 200.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 426.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036445, HPA057988" Uncertain Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: BEWO - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA036445: AB_10670106, HPA057988: AB_2683572" "unprognostic (1.28e-3)" "unprognostic (2.99e-2)" "unprognostic (9.50e-2)" "unprognostic (6.97e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (7.74e-2)" "unprognostic (7.81e-3)" "unprognostic (4.80e-2)" "unprognostic (4.09e-2)" "unprognostic (2.76e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.17e-4)" "unprognostic (4.76e-2)" "unprognostic (3.06e-2)" "unprognostic (4.34e-2)" "unprognostic (2.03e-1)" SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 252.7;Oligodendrocytes: 339.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 50: Enterocytes - Absorption" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Astrocytes: 45.5;Excitatory neurons: 106.4;Inhibitory neurons: 157.5;Microglial cells: 160.5;Oligodendrocyte precursor cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" SHC3 "N-Shc, NSHC, SHCC" ENSG00000148082 "SHC adaptor protein 3" Q92529 9 89005771-89178818 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 152.9;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 319.6" "Cancer enriched" "Detected in some" 5 "glioma: 5.1" "Group enriched" "Detected in many" 9 "amygdala: 16.8;basal ganglia: 24.9;cerebral cortex: 28.1;hippocampal formation: 23.6;white matter: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.9;Sarcoma: 5.8" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031427, HPA046656, HPA072448" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 27: TE 441.T - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "HPA031427: AB_2673877, HPA046656: AB_2679740, HPA072448: AB_2686521" "unprognostic (6.22e-2)" "unprognostic (5.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-4)" "unprognostic (2.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (2.72e-3)" "unprognostic (7.39e-2)" "unprognostic (1.53e-7)" "unprognostic (8.33e-2)" "unprognostic (1.05e-1)" "unprognostic (9.01e-2)" "unprognostic (9.84e-4)" SHISAL2A "FAM159A, MGC52498" ENSG00000182183 "Shisa like 2A" Q6UWV7 1 52633168-52669683 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;intestine: 3.7;lymphoid tissue: 5.6" "Cell type enhanced" "Detected in some" "B-cells: 33.5;NK-cells: 20.2;Plasma cells: 9.2;T-cells: 20.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "hypothalamus: 8.7" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 10.1;NK-cells: 5.9;T-cells: 7.0" "Group enriched" "Detected in some" 9 "Leukemia: 1.3;lymphoma: 3.3;Myeloma: 4.2" "Adipose visceral - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Region enhanced" "Detected in some" "hypothalamus: 4.0" "Low region specificity" "Detected in some" HPA030744 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "HPA030744: AB_10963060" "unprognostic (7.94e-6)" "unprognostic (8.50e-3)" "unprognostic (8.29e-3)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (9.67e-4)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (2.22e-2)" "unprognostic (4.45e-2)" "unprognostic (2.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-3)" "unprognostic (7.27e-2)" "unprognostic (2.79e-1)" "unprognostic (6.50e-2)" "unprognostic (2.64e-2)" SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 25.6;Cone photoreceptor cells: 29.3;Microglial cells: 23.7;Peritubular cells: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 18.6" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051646 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 77: Retina - Visual perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: AB_2681562" "unprognostic (8.65e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (6.99e-3)" "unprognostic (8.05e-2)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (9.73e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (1.93e-1)" "unprognostic (7.67e-3)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Hofbauer cells: 77.2;Macrophages: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 69: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 29.1;NK-cells: 133.2;T-cells: 52.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Cancer enriched" "Detected in some" 8 "Leukemia: 14.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 25.6;Langerhans cells: 10.1;Plasma cells: 41.1;T-cells: 38.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cancer enhanced" "Detected in some" "Leukemia: 13.5;lymphoma: 38.5" "Adipose subcutaneous - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Group enriched" "Detected in some" 5 "B-cells: 22.0;Late spermatids: 23.2;NK-cells: 39.8;Plasma cells: 18.2;Serous glandular cells: 12.7;T-cells: 34.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 9.2;lymphoma: 34.1" "Breast - Plasma cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enhanced" "Detected in many" "Late spermatids: 237.3;Oligodendrocytes: 269.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 8 "Astrocytes: 130.3;Inhibitory neurons: 317.1;Oligodendrocyte precursor cells: 359.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Group enriched" "Detected in many" 5 "Bile duct cancer: 6.0;Bone cancer: 15.3;breast cancer: 13.1" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 262.1;Hepatocytes: 173.7;Proximal enterocytes: 79.5;Proximal tubular cells: 96.9;Respiratory ciliated cells: 71.9" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" SLC2A10 GLUT10 ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 41.0;Intestinal goblet cells: 67.2;Prostatic glandular cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 75 "basophil: 20.9" "Lineage enriched" "Detected in single" 75 "granulocytes: 20.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Club cells: 222.1;Distal enterocytes: 465.4;Gastric mucus-secreting cells: 191.4;Intestinal goblet cells: 261.7;Ionocytes: 217.2;Paneth cells: 187.6;Prostatic glandular cells: 326.4;Proximal enterocytes: 260.4;Respiratory ciliated cells: 403.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 27.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 74: Pancreatic cells - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.2;testis: 40.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 21.7;Cytotrophoblasts: 33.0;Glandular and luminal cells: 22.7;Proximal enterocytes: 42.2;Syncytiotrophoblasts: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.8" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA049391: AB_2680743, HPA059078: AB_2732630" "unprognostic (4.53e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (9.03e-3)" "unprognostic (2.12e-3)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (4.36e-2)" "unprognostic (4.39e-3)" "unprognostic (4.82e-2)" "unprognostic (2.04e-3)" "prognostic favorable (5.51e-6)" "unprognostic (3.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 331.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 99.1;Endometrial stromal cells: 73.6;Proximal tubular cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 9.3;eosinophil: 14.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 14.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 70: Basal prostatic cells - Lipid metabolism" "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 570.8;Proximal tubular cells: 381.6;Squamous epithelial cells: 348.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" SLFN14 ENSG00000236320 "Schlafen family member 14" P0C7P3 17 35543985-35560819 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "bone marrow: 3.9" "Group enriched" "Detected in some" 4 "Erythroid cells: 9.9;granulocytes: 5.2;Langerhans cells: 11.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.1" "Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022994, HPA023065" Uncertain NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 4: Platelets - Platelet activation" "HPA022994: AB_10670035, HPA023065: AB_2671055" "unprognostic (4.27e-3)" "unprognostic (4.72e-4)" "unprognostic (1.21e-1)" "unprognostic (6.43e-2)" "unprognostic (1.07e-3)" "unprognostic (6.50e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-1)" "unprognostic (5.33e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-1)" "unprognostic (7.59e-8)" "unprognostic (1.21e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-3)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 199.3;Fibroblasts: 112.0;Smooth muscle cells: 101.1;Thymic epithelial cells: 48.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 227.7;Endothelial cells: 126.4;Late spermatids: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.2;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 5 "granulocytes: 46.2;monocytes: 22.2" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB005389: AB_656608" "unprognostic (8.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-1)" "unprognostic (6.85e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (2.30e-1)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-3)" "unprognostic (3.15e-2)" SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 414.9;dendritic cells: 295.3;Kupffer cells: 291.8;Macrophages: 294.3;monocytes: 701.3;NK-cells: 382.2;Plasma cells: 255.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skin - Keratinocyte (granular), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.6;Distal enterocytes: 151.2;Proximal enterocytes: 339.5;Proximal tubular cells: 107.9;Syncytiotrophoblasts: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cancer enhanced" "Detected in all" "prostate cancer: 42.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 50: Enterocytes - Absorption" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" SMTNL2 FLJ42461 ENSG00000188176 "Smoothelin like 2" Q2TAL5 17 4583999-4608319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 500.8;tongue: 136.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 15.8;Distal tubular cells: 28.0;Proximal tubular cells: 36.9;Skeletal myocytes: 79.2;Thymic epithelial cells: 30.7" "Cancer enhanced" "Detected in many" "renal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 10.1" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025706 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 6: BEWO - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA025706: AB_1848935" "unprognostic (8.62e-2)" "unprognostic (5.40e-2)" "unprognostic (7.13e-2)" "unprognostic (2.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.87e-2)" "unprognostic (4.89e-3)" "unprognostic (2.73e-1)" "unprognostic (3.73e-3)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (5.89e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-3)" "unprognostic (2.22e-1)" SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 31.3" "Cell type enhanced" "Detected in some" "B-cells: 8.9;dendritic cells: 9.9;Kupffer cells: 11.1;Langerhans cells: 12.5;Macrophages: 9.0;NK-cells: 23.3;Plasma cells: 11.5;T-cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Breast - Plasma cells, Heart muscle - Cardiomyocytes, Prostate - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA071127: AB_2686346" "unprognostic (1.03e-2)" "prognostic favorable (1.39e-4)" "unprognostic (2.20e-2)" "unprognostic (6.19e-4)" "unprognostic (3.05e-1)" "unprognostic (2.85e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (3.24e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.58e-4)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 422.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 204.9;Cholangiocytes: 192.5;Mucus glandular cells: 172.8;Salivary duct cells: 213.8;Sertoli cells: 171.4;Squamous epithelial cells: 278.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Prostate - Prostate basal glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240, HPA070776" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067, HPA070776: " "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 148.0;monocytes: 37.4;NK-cells: 61.8;Plasma cells: 81.0;T-cells: 56.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "lymphoma: 41.9;Myeloma: 17.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 117.8" "Group enriched" "Detected in some" 87 "Early spermatids: 935.7;Late spermatids: 369.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 49: Early spermatids - Spermatogenesis" "HPA041927: AB_10794162, HPA061302: AB_2684475" "unprognostic (2.48e-2)" "unprognostic (6.37e-4)" "unprognostic (6.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.09e-3)" "unprognostic (9.43e-6)" "unprognostic (6.67e-3)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (3.43e-1)" "unprognostic (2.88e-1)" "unprognostic (4.47e-1)" "unprognostic (2.01e-2)" SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 690.5;Endometrial stromal cells: 1211.8;Endothelial cells: 711.5;Fibroblasts: 1071.9;Peritubular cells: 1109.1;Schwann cells: 921.2;Sertoli cells: 1409.7;Smooth muscle cells: 1089.7;Theca cells: 924.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cancer enhanced" "Detected in all" "Brain cancer: 2554.7;skin cancer: 2512.0" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" SPNS3 "MGC29671, SLC62A3" ENSG00000182557 "Sphingolipid transporter 3 (putative)" Q6ZMD2 17 4433940-4488208 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 31.2" "Cell type enhanced" "Detected in many" "dendritic cells: 62.2;Langerhans cells: 19.4;monocytes: 14.2;Proximal tubular cells: 45.8;T-cells: 21.9" "Cancer enhanced" "Detected in many" "renal cancer: 2.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "eosinophil: 354.8;plasmacytoid DC: 127.7" "Group enriched" "Detected in many" 37 "dendritic cells: 127.7;granulocytes: 354.8" "Cancer enriched" "Detected in some" 7 "Leukemia: 39.3" "Liver - Hepatocytes, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023928 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 60: Proximal tubular cells - Absorption" "HPA023928: AB_1844393" "unprognostic (4.39e-2)" "unprognostic (8.10e-5)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.94e-4)" "unprognostic (2.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.81e-2)" "unprognostic (6.46e-2)" "unprognostic (1.37e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (6.18e-2)" "unprognostic (6.57e-2)" "unprognostic (4.13e-2)" "unprognostic (9.69e-2)" SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 816.2;Endothelial cells: 371.4;Fibroblasts: 221.9;Leydig cells: 411.8;Thymic epithelial cells: 318.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 167.0;Proximal tubular cells: 95.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 120.6;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 46: Non-specific - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favorable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 70.2;Fibroblasts: 246.3;Granulosa cells: 146.3;Leydig cells: 106.3;Melanocytes: 76.6;Peritubular cells: 100.2;Smooth muscle cells: 96.6" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cancer enhanced" "Detected in many" "skin cancer: 195.4" "Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81413021-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 273.0;Excitatory neurons: 259.2;Inhibitory neurons: 341.4;Microglial cells: 330.2;Oligodendrocytes: 321.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "CAB020834: , HPA068605: AB_2732116, HPA071780: " "unprognostic (4.62e-2)" "unprognostic (1.96e-3)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.78e-3)" "unprognostic (2.36e-3)" "unprognostic (6.01e-2)" "unprognostic (1.01e-2)" "unprognostic (3.04e-3)" "unprognostic (6.56e-2)" "unprognostic (9.81e-2)" "unprognostic (4.39e-3)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.8;Fibroblasts: 26.6;Leydig cells: 18.6;Peritubular cells: 15.4;Schwann cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 11.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 265.1;Inhibitory neurons: 249.3;Microglial cells: 248.1;Oligodendrocytes: 517.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 134.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Macrophages, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 46: Non-specific - Unknown function" "Cluster 12: Non-specific - Chromatin organization" "CAB017189: , HPA057099: AB_2683336" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Fibroblasts: 138.9;Leydig cells: 188.9;Peritubular cells: 269.9;Skeletal myocytes: 172.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 888.4;Oligodendrocytes: 659.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Neuroblastoma: 12.1;skin cancer: 9.7;testis cancer: 8.3;thyroid cancer: 3.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Group enriched" "Detected in many" 5 "Endothelial cells: 127.8;Fibroblasts: 127.2;Hofbauer cells: 147.9;Kupffer cells: 242.8;Macrophages: 205.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Cancer enriched" "Detected in single" 64 "Leukemia: 14.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 65.7;Early spermatids: 320.6;Excitatory neurons: 84.7;Late spermatids: 77.7;NK-cells: 226.8;T-cells: 125.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cancer enhanced" "Detected in many" "Myeloma: 7.4" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 1: T-cells - Immune response" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Ductal cells: 5.0;Glandular and luminal cells: 3.9;Plasma cells: 5.0;Proximal enterocytes: 10.6;Skeletal myocytes: 4.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 54.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: Myeloma - Humoral immune response" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" STON2 "STN2, STNB2" ENSG00000140022 "Stonin 2" Q8WXE9 14 81260656-81436465 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 79.8" "Cell type enriched" "Detected in many" 4 "Astrocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.2" "Lineage enriched" "Detected in single" 4 "monocytes: 1.2" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003086 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 63: Astrocytes - Nervous system maintenance" "Nucleoli, Cytosol" "HPA003086: AB_2302748" "unprognostic (5.28e-2)" "unprognostic (9.83e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.50e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (3.30e-1)" "unprognostic (9.88e-2)" "unprognostic (9.19e-2)" "unprognostic (5.82e-3)" "unprognostic (1.37e-1)" "unprognostic (6.15e-2)" "unprognostic (1.44e-1)" STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 126.1;Langerhans cells: 388.2;Macrophages: 154.2;monocytes: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cancer enhanced" "Detected in many" "lymphoma: 7.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Endothelial cells, Liver - Neutrophils, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 75: Myeloid cells - Innate immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.3;Cone photoreceptor cells: 187.8;Excitatory neurons: 239.8;Horizontal cells: 123.0;Inhibitory neurons: 153.7;Rod photoreceptor cells: 182.5" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 87.0;Excitatory neurons: 62.5;Horizontal cells: 166.0;Inhibitory neurons: 104.7" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 148.2;B-cells: 208.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 533.0;Bipolar cells: 352.9;Excitatory neurons: 487.8;Inhibitory neurons: 471.5;Microglial cells: 307.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 388.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 23: Langerhans cells - Immune response" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" SYT12 SRG1 ENSG00000173227 "Synaptotagmin 12" Q8IV01 11 67006778-67050863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 22.5;liver: 17.6;parathyroid gland: 63.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Basal respiratory cells: 11.0;Breast myoepithelial cells: 8.1;Excitatory neurons: 38.8;Inhibitory neurons: 21.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 33.8;cervical cancer: 44.7" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011006, HPA074255" Enhanced NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 65: Breast cancer - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "HPA011006: AB_2286996, HPA074255: " "unprognostic (2.72e-2)" "unprognostic (2.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.12e-3)" "unprognostic (4.47e-3)" "unprognostic (3.88e-2)" "unprognostic (1.20e-1)" "unprognostic (3.73e-2)" "unprognostic (2.04e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (4.13e-4)" "unprognostic (2.75e-1)" "unprognostic (9.86e-4)" "unprognostic (4.21e-2)" "unprognostic (7.38e-2)" "unprognostic (2.42e-2)" "unprognostic (9.85e-2)" TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 81.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cancer enhanced" "Detected in some" "Brain cancer: 2.3;ovarian cancer: 1.3" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 32: Neurons - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1685.3;Basal respiratory cells: 2892.6;Basal squamous epithelial cells: 1804.4;Club cells: 2016.7;Ductal cells: 1941.6;Ionocytes: 2053.2;Squamous epithelial cells: 2789.0;Suprabasal keratinocytes: 2443.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 923.2" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 5: Bronchus - Unknown function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 235.3;dendritic cells: 89.0;Langerhans cells: 70.5;Macrophages: 85.3;monocytes: 75.4;NK-cells: 128.5;Plasma cells: 202.8;T-cells: 211.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 9.8;lymphoma: 16.6;Myeloma: 7.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enhanced" "Detected in some" "Adipocytes: 24.0;Endothelial cells: 17.6;Erythroid cells: 82.7;granulocytes: 30.9;Late spermatids: 18.5;Microglial cells: 28.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 27.9" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 40.4;intestine: 25.6;lymphoid tissue: 58.6" "Cell type enhanced" "Detected in many" "B-cells: 110.1;monocytes: 54.0;NK-cells: 192.7;T-cells: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 33.5;lymphoma: 27.3" "Adipose subcutaneous - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear bodies" "HPA069743: AB_2686186" "prognostic favorable (3.83e-4)" "prognostic favorable (4.20e-4)" "unprognostic (9.23e-2)" "unprognostic (3.84e-2)" "unprognostic (1.28e-3)" "prognostic favorable (1.86e-5)" "unprognostic (6.22e-3)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (3.55e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (7.18e-2)" "unprognostic (3.81e-2)" TBL1Y TBL1 ENSG00000092377 "Transducin beta like 1 Y-linked" Q9BQ87 Y 6910686-7101970 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 2.9;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 4.3;Inhibitory neurons: 2.2;Prostatic glandular cells: 3.5;Squamous epithelial cells: 5.2" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.7" "Region enhanced" "Detected in single" "basal ganglia: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.9" "Prostate - Prostate glandular cells" "HPA050857, HPA060073" Uncertain Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 69: BICR 18 - Unknown function" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "HPA050857: , HPA060073: AB_2684196" "unprognostic (2.81e-3)" "unprognostic (2.94e-1)" "unprognostic (3.06e-1)" "unprognostic (7.76e-2)" "unprognostic (1.17e-2)" "unprognostic (1.28e-1)" "unprognostic (2.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.24e-2)" TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 111.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Bone cancer: 4.0" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" TBX6 ENSG00000149922 "T-box transcription factor 6" O95947 16 30085793-30091924 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 6.6;Ionocytes: 6.4;Squamous epithelial cells: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.2" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062498 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 5: Bronchus - Unknown function" Nucleoplasm "HPA062498: AB_2732686" "unprognostic (2.47e-1)" "unprognostic (1.32e-3)" "unprognostic (5.62e-5)" "unprognostic (1.49e-1)" "unprognostic (4.76e-2)" "unprognostic (2.35e-2)" "unprognostic (3.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (3.87e-1)" "unprognostic (2.76e-2)" "unprognostic (2.95e-1)" "unprognostic (4.21e-2)" "unprognostic (5.05e-3)" "unprognostic (4.26e-2)" TCEAL1 "p21, pp21, SIIR, WEX9" ENSG00000172465 "Transcription elongation factor A like 1" Q15170 X 103628704-103630953 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 281.1;Peritubular cells: 380.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057345, HPA060384, HPA076762" Approved Enhanced Nucleoplasm No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 48: Non-specific - RNA binding" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA057345: , HPA060384: AB_2732648, HPA076762: " "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.60e-3)" "unprognostic (6.09e-2)" "unprognostic (2.03e-2)" "unprognostic (9.85e-3)" "unprognostic (6.54e-2)" "unprognostic (4.80e-2)" "unprognostic (2.62e-1)" "unprognostic (2.56e-1)" "unprognostic (5.56e-2)" "unprognostic (8.76e-2)" TCEAL4 "FLJ21174, WEX7" ENSG00000133142 "Transcription elongation factor A like 4" Q96EI5 X 103576231-103587729 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 961.4;Leydig cells: 1503.7;Peritubular cells: 1793.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 48: Non-specific - RNA binding" "Cluster 15: Smooth muscle cells - Muscle contraction" "unprognostic (2.21e-1)" "unprognostic (2.21e-1)" "unprognostic (6.17e-3)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.08e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (4.16e-1)" "unprognostic (2.02e-2)" "unprognostic (7.49e-2)" "unprognostic (3.35e-2)" "unprognostic (5.46e-2)" "unprognostic (7.63e-2)" TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 312.8;Microglial cells: 428.7;Oligodendrocyte precursor cells: 592.1;Oligodendrocytes: 1428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 46.4;Alveolar cells type 2: 56.7;Astrocytes: 74.0;Leydig cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" TDRKH TDRD2 ENSG00000182134 "Tudor and KH domain containing" Q9Y2W6 1 151770107-151791416 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, RNA-mediated gene silencing, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 30.1;testis: 22.2" "Group enriched" "Detected in many" 4 "Early spermatids: 19.4;Late spermatids: 62.7;Spermatocytes: 45.0;Spermatogonia: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016419, HPA019625" Approved Approved Centrosome,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: Non-specific - RNA binding" "Cluster 6: Late spermatids - Spermatogenesis" Cytosol Centrosome "HPA016419: AB_1857870, HPA019625: AB_1857871" "unprognostic (2.27e-3)" "unprognostic (2.89e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (2.63e-1)" "unprognostic (2.91e-1)" "unprognostic (2.06e-1)" "unprognostic (3.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.63e-2)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-3)" "unprognostic (1.14e-1)" TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 190.9;Astrocytes: 223.6;Skeletal myocytes: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "HPA057339: AB_2683413, HPA062471: AB_2684773" "unprognostic (1.00e-1)" "unprognostic (2.53e-2)" "unprognostic (8.84e-2)" "unprognostic (9.93e-3)" "unprognostic (2.05e-2)" "unprognostic (4.50e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "unprognostic (4.40e-3)" "unprognostic (8.39e-2)" "unprognostic (4.76e-2)" "unprognostic (1.41e-2)" "unprognostic (7.08e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "unprognostic (2.18e-2)" TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 127.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 34.7;Cytotrophoblasts: 53.5;Proximal enterocytes: 39.3;Skeletal myocytes: 28.7;Syncytiotrophoblasts: 28.3" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 621.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Prostate - Smooth muscle cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 210.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.3;Oligodendrocytes: 81.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 159.7;Cytotrophoblasts: 288.0;Extravillous trophoblasts: 285.6;Melanocytes: 165.5;Squamous epithelial cells: 140.5;Syncytiotrophoblasts: 709.8" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 96.0;Basal squamous epithelial cells: 106.2;Breast glandular cells: 58.0;Breast myoepithelial cells: 64.1;Cytotrophoblasts: 89.6;Extravillous trophoblasts: 59.0;Squamous epithelial cells: 71.2;Suprabasal keratinocytes: 93.4;Syncytiotrophoblasts: 109.0" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 70.8" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "dendritic cells: 23.3;Hofbauer cells: 48.3;Kupffer cells: 45.1;Macrophages: 71.6;Microglial cells: 58.4;Proximal tubular cells: 81.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Group enriched" "Detected in some" 14 "Leukemia: 13.1;lymphoma: 18.0;Rhabdoid: 6.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA050528, HPA063577" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm Cytosol "CAB032260: AB_2202845, HPA050528: , HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 46.3;Microglial cells: 14.6;Serous glandular cells: 10.9;T-cells: 66.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 19 "Leukemia: 3.6;lymphoma: 3.1;Myeloma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 145.8;Bipolar cells: 162.8;Horizontal cells: 99.3;Inhibitory neurons: 480.4;Microglial cells: 103.1;Oligodendrocyte precursor cells: 251.3" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 10.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 8 "NK-cells: 60.8;T-cells: 79.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Group enriched" "Detected in some" 7 "lymphoma: 4.5;Myeloma: 1.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 445.3;Late spermatids: 482.9;Leydig cells: 362.3;Melanocytes: 360.5;Peritubular cells: 748.7;Theca cells: 461.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 12: Non-specific - Chromatin organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 611.3;Late spermatids: 1387.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" TLR10 CD290 ENSG00000174123 "Toll like receptor 10" Q9BXR5 4 38772238-38782990 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 47.9" "Cell type enhanced" "Detected in some" "B-cells: 59.4;dendritic cells: 13.2;Microglial cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 39.0;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 5 "B-cells: 39.0" "Cancer enriched" "Detected in some" 5 "lymphoma: 27.2" "Adipose visceral - Neutrophils, Prostate - T-cells" "Low region specificity" "Detected in many" HPA001940 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "Plasma membrane" "Endoplasmic reticulum" "HPA001940: " "unprognostic (5.41e-5)" "unprognostic (2.41e-4)" "unprognostic (1.91e-3)" "unprognostic (8.22e-4)" "unprognostic (6.48e-2)" "unprognostic (9.98e-4)" "unprognostic (9.31e-2)" "unprognostic (8.76e-3)" "unprognostic (4.08e-3)" "unprognostic (7.26e-2)" "unprognostic (8.76e-2)" "unprognostic (6.90e-2)" "unprognostic (2.98e-3)" "unprognostic (3.90e-1)" "unprognostic (1.81e-2)" "unprognostic (3.14e-3)" "unprognostic (1.88e-2)" TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Low cancer specificity" "Detected in some" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 52.0;granulocytes: 30.8;Hofbauer cells: 31.4;Langerhans cells: 43.5;monocytes: 38.7;NK-cells: 66.1;T-cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 67.0;lymphoma: 48.3;Myeloma: 71.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 409.4" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 337.4;Serous glandular cells: 656.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 21: Serous glandular cells - Salivary secretion" "Golgi apparatus" "HPA049314: AB_2680708, HPA076949: AB_2686820" "prognostic unfavorable (7.71e-4)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (8.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.03e-3)" "unprognostic (2.42e-2)" "unprognostic (2.49e-1)" "unprognostic (4.85e-1)" "unprognostic (9.06e-2)" "unprognostic (8.09e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.16e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" TMEM156 FLJ23235 ENSG00000121895 "Transmembrane protein 156" Q8N614 4 38966744-39032922 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in many" "B-cells: 82.4;Microglial cells: 66.6;NK-cells: 28.6;Plasma cells: 92.1;Schwann cells: 23.4;T-cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 74.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 46: Non-specific - Unknown function" "Cluster 62: B-cells - B-cell activation" "prognostic favorable (4.09e-4)" "unprognostic (7.36e-3)" "unprognostic (3.31e-3)" "unprognostic (4.17e-3)" "unprognostic (1.82e-1)" "unprognostic (1.01e-3)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (9.45e-3)" "unprognostic (5.17e-2)" "unprognostic (8.73e-4)" "unprognostic (3.89e-1)" "unprognostic (1.74e-2)" "unprognostic (3.92e-4)" "unprognostic (9.06e-2)" TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" "unprognostic (3.49e-1)" "unprognostic (1.18e-1)" "unprognostic (2.95e-2)" "unprognostic (1.52e-3)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (7.97e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "prognostic favorable (2.36e-9)" "unprognostic (4.37e-2)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (1.53e-3)" TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Endometrial stromal cells: 17.6;Enteroendocrine cells: 16.3;Granulosa cells: 50.1" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Group enriched" "Detected in many" 4 "Suprabasal keratinocytes: 338.0;Syncytiotrophoblasts: 812.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 62.3;head and neck cancer: 48.8" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved "Plasma membrane,Cytosol" NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 4: Platelets - Platelet activation" "Plasma membrane" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" TMEM63A KIAA0792 ENSG00000196187 "Transmembrane protein 63A" O94886 1 225845536-225882380 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 365.5;salivary gland: 121.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 305.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066504, HPA066936, HPA068918" Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 65: Breast cancer - Unknown function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Vesicles, Centriolar satellite" "HPA066504: AB_2685680, HPA066936: AB_2685751, HPA068918: AB_2686057" "unprognostic (5.31e-2)" "unprognostic (3.46e-2)" "unprognostic (2.14e-2)" "prognostic favorable (8.79e-4)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.92e-2)" TMOD1 "D9S57E, ETMOD, TMOD" ENSG00000136842 "Tropomodulin 1" P28289 9 97501180-97601743 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 250.0;tongue: 255.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.9;Erythroid cells: 81.4;granulocytes: 96.9;Pancreatic endocrine cells: 77.3;Sertoli cells: 49.8;Skeletal myocytes: 77.2" "Group enriched" "Detected in many" 4 "glioma: 21.6;ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 90.1" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" HPA051202 Enhanced NA NA 9400 "Cluster 40: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA051202: AB_2681387" "unprognostic (8.54e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-3)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "unprognostic (2.62e-3)" "unprognostic (2.82e-1)" "unprognostic (3.09e-1)" "unprognostic (2.09e-1)" "unprognostic (2.91e-1)" "unprognostic (1.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.42e-1)" "unprognostic (2.02e-1)" "unprognostic (4.88e-5)" TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 378.6;Suprabasal keratinocytes: 272.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 14.1;Langerhans cells: 10.9;Smooth muscle cells: 12.4;Spermatocytes: 22.4;Thymic epithelial cells: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.1" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 15 "Plasma cells: 468.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cancer enriched" "Detected in some" 12 "Myeloma: 633.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Apoptosis Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 205.0;vagina: 74.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.8;Basal prostatic cells: 111.5;Basal squamous epithelial cells: 199.6;Mucus glandular cells: 45.9;Salivary duct cells: 103.3;Squamous epithelial cells: 55.5;Suprabasal keratinocytes: 46.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 77.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 75.9" "Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (4.16e-2)" "unprognostic (9.83e-2)" "unprognostic (1.01e-1)" "unprognostic (3.40e-2)" "unprognostic (3.68e-4)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.89e-1)" "unprognostic (8.02e-3)" "unprognostic (2.01e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (3.72e-1)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Basal squamous epithelial cells: 251.1;Skeletal myocytes: 81.2;Squamous epithelial cells: 157.7;Suprabasal keratinocytes: 189.8" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 110.8;Gallbladder cancer: 189.5;head and neck cancer: 118.7" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Cell type enhanced" "Detected in all" "monocytes: 1100.0;Skeletal myocytes: 933.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: Non-specific - RNA binding" "Cluster 74: Pancreatic cells - Mixed function" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 277.1;Kupffer cells: 268.7;Macrophages: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 9500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 59: Fibroblasts - Metabolism" "Cluster 69: Macrophages - Innate immune response" "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.1;Excitatory neurons: 100.4;Inhibitory neurons: 104.7;Spermatocytes: 99.2" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 52: Endometrial stromal cells - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enriched" "Detected in many" 6 "T-cells: 504.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Group enriched" "Detected in many" 6 "Leukemia: 132.2;lymphoma: 81.4" "Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skeletal muscle - Fibroblasts, Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 130.5" "Cell type enhanced" "Detected in many" "B-cells: 125.8;granulocytes: 60.4;monocytes: 103.7;NK-cells: 236.2;T-cells: 162.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 46.3;lymphoma: 40.5;Myeloma: 68.6" "Adipose subcutaneous - T-cells, Heart muscle - T-cells, Liver - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 37.9" "Cell type enriched" "Detected in single" 9 "T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.1;memory CD4 T-cell: 81.9;memory CD8 T-cell: 124.0;naive CD4 T-cell: 77.1;naive CD8 T-cell: 81.0;T-reg: 167.9" "Lineage enriched" "Detected in many" 118 "T-cells: 167.9" "Group enriched" "Detected in some" 54 "Bone cancer: 2.5;Leukemia: 8.1" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.13e-2)" "unprognostic (4.08e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-4)" "unprognostic (5.20e-3)" "unprognostic (1.18e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (7.19e-3)" "unprognostic (2.48e-3)" "unprognostic (8.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-4)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (2.89e-1)" "unprognostic (6.49e-2)" TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 24.1" "Cell type enriched" "Detected in single" 15 "T-cells: 12.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.1;memory CD4 T-cell: 143.4;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.2;naive CD8 T-cell: 80.1;T-reg: 190.6" "Lineage enriched" "Detected in many" 184 "T-cells: 190.6" "Group enriched" "Detected in some" 7 "Leukemia: 1.1;lymphoma: 2.8;Rhabdoid: 1.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - Podocytes, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (5.88e-3)" "unprognostic (9.98e-4)" "unprognostic (2.31e-2)" "unprognostic (2.23e-2)" "unprognostic (9.88e-5)" "unprognostic (1.94e-3)" "unprognostic (7.22e-3)" "unprognostic (9.30e-3)" "unprognostic (2.82e-3)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (7.57e-5)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.02e-1)" TRAV8-3 ENSG00000211787 "T cell receptor alpha variable 8-3" A0A0A6YYJ7 14 21852558-21853006 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 71.1" "Cell type enriched" "Detected in single" 17 "T-cells: 4.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 138.2;T-reg: 153.1" "Lineage enriched" "Detected in many" 47 "T-cells: 153.1" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (7.74e-4)" "unprognostic (5.25e-5)" "unprognostic (8.88e-4)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (9.64e-5)" "unprognostic (8.20e-2)" "unprognostic (1.25e-2)" "unprognostic (1.38e-2)" "unprognostic (6.44e-2)" "unprognostic (2.13e-2)" "unprognostic (1.46e-1)" "unprognostic (2.66e-5)" "unprognostic (2.99e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" TRAV8-6 ENSG00000211795 "T cell receptor alpha variable 8-6" A0A0B4J262 14 21978459-21979120 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 24.7" "Group enriched" "Detected in some" 5 "Spermatocytes: 1.8;T-cells: 3.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 89.3;memory CD8 T-cell: 64.2;naive CD4 T-cell: 92.6;naive CD8 T-cell: 38.7;T-reg: 125.0" "Lineage enriched" "Detected in many" 45 "T-cells: 125.0" "Group enriched" "Detected in some" 17 "lymphoma: 3.6;Rhabdoid: 14.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (9.23e-4)" "unprognostic (5.47e-3)" "unprognostic (1.27e-3)" "unprognostic (7.80e-2)" "unprognostic (7.74e-5)" "unprognostic (2.88e-3)" "unprognostic (5.41e-3)" "unprognostic (2.59e-3)" "unprognostic (2.24e-2)" "unprognostic (9.25e-2)" "unprognostic (2.92e-1)" "unprognostic (9.78e-5)" "unprognostic (4.65e-1)" "unprognostic (2.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-3)" TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 17 "NK-cells: 443.4;T-cells: 435.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 98.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" TRBJ2-7 "TCRBJ2S7, TRBJ27" ENSG00000211771 "T cell receptor beta joining 2-7" A0A0A0MT78 7 142797456-142797502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 45.4;lymphoid tissue: 155.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 10.8" "Group enriched" "Detected in all" 7 "MAIT T-cell: 1275.2;memory CD4 T-cell: 2387.1;memory CD8 T-cell: 2649.6;naive CD4 T-cell: 2393.9;naive CD8 T-cell: 2831.0;T-reg: 4224.6" "Lineage enriched" "Detected in all" 18 "T-cells: 4224.6" "Cancer enhanced" "Detected in many" "Leukemia: 87.6;lymphoma: 31.5" "Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (9.07e-3)" "unprognostic (9.26e-3)" "unprognostic (4.37e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.14e-3)" "unprognostic (2.57e-3)" "unprognostic (6.68e-3)" "unprognostic (9.60e-2)" "unprognostic (2.17e-2)" "unprognostic (6.18e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (7.27e-2)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" TRBV10-3 "TCRBV10S3, TCRBV12S1A1N2, TRBV103" ENSG00000275791 "T cell receptor beta variable 10-3" A0A0K0K1G6 7 142544212-142544685 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 88.6" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 1.8;Late spermatids: 1.7;T-cells: 5.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 160.1;T-reg: 203.1" "Lineage enriched" "Detected in single" 375 "T-cells: 203.1" "Cancer enriched" "Detected in single" 27 "Leukemia: 3.5" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.61e-3)" "unprognostic (4.86e-3)" "unprognostic (2.44e-2)" "unprognostic (8.96e-3)" "unprognostic (3.16e-1)" "unprognostic (4.23e-6)" "unprognostic (9.84e-4)" "unprognostic (7.96e-2)" "unprognostic (4.05e-2)" "unprognostic (7.99e-4)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (9.59e-6)" "unprognostic (5.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 53.4" "Cell type enriched" "Detected in some" 4 "T-cells: 11.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 50.8;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.1;naive CD8 T-cell: 53.5;T-reg: 88.5" "Lineage enriched" "Detected in single" 191 "T-cells: 88.5" "Cancer enriched" "Detected in single" 14 "Leukemia: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.62e-3)" "unprognostic (8.91e-4)" "unprognostic (1.14e-2)" "unprognostic (5.81e-3)" "unprognostic (2.38e-2)" "unprognostic (2.29e-4)" "unprognostic (3.96e-3)" "unprognostic (3.62e-3)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (9.78e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" TRBV2 "TCRBV22S1A2N1T, TCRBV2S1" ENSG00000226660 "T cell receptor beta variable 2" A0A1B0GX68 7 142300924-142301432 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "lymphoid tissue: 89.2" "Group enriched" "Detected in some" 6 "Erythroid cells: 14.0;T-cells: 7.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 120.3;memory CD8 T-cell: 64.5;naive CD4 T-cell: 71.5;naive CD8 T-cell: 44.5;T-reg: 122.7" "Lineage enriched" "Detected in many" 21 "T-cells: 122.7" "Cancer enriched" "Detected in single" 18 "lymphoma: 2.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.62e-4)" "unprognostic (4.94e-4)" "unprognostic (5.79e-2)" "unprognostic (1.29e-3)" "unprognostic (1.09e-1)" "unprognostic (4.71e-5)" "unprognostic (3.60e-2)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (1.16e-2)" "unprognostic (1.94e-2)" "unprognostic (1.77e-1)" "unprognostic (3.70e-5)" "unprognostic (3.83e-1)" "unprognostic (6.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.41e-2)" TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 161.4" "Cell type enriched" "Detected in some" 22 "T-cells: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 351.7" "Lineage enriched" "Detected in many" 115 "T-cells: 351.7" "Cancer enriched" "Detected in some" 101 "Leukemia: 262.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "prognostic favorable (4.40e-5)" "unprognostic (1.39e-2)" "prognostic favorable (8.49e-4)" "unprognostic (8.83e-2)" "unprognostic (2.69e-3)" "unprognostic (4.34e-2)" "unprognostic (8.75e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.30e-2)" "unprognostic (8.86e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (3.41e-2)" TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 4 "T-cells: 4.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Skeletal muscle - Skeletal myocytes, Thyroid - T-cells" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 2: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 1.8;T-cells: 5.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Cancer enriched" "Detected in single" 5 "Leukemia: 3.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" TRBV29-1 "TCRBV29S1, TCRBV4S1A1T, TRBV291" ENSG00000232869 "T cell receptor beta variable 29-1" A0A5B7 7 142740206-142740894 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 98.5" "Cell type enriched" "Detected in single" 15 "T-cells: 4.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "MAIT T-cell: 45.1;memory CD4 T-cell: 128.6;memory CD8 T-cell: 83.2;naive CD4 T-cell: 137.8;naive CD8 T-cell: 110.8;T-reg: 178.2" "Lineage enriched" "Detected in many" 69 "T-cells: 178.2" "Cancer enriched" "Detected in single" 11 "Myeloma: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 2: T-cells - T-cell receptor" "prognostic favorable (1.23e-4)" "unprognostic (9.31e-4)" "unprognostic (1.29e-1)" "unprognostic (8.13e-3)" "unprognostic (3.28e-2)" "unprognostic (3.47e-4)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.45e-1)" "unprognostic (2.46e-2)" "unprognostic (2.29e-1)" "unprognostic (2.05e-1)" TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 14.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 2: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 22.1;pancreas: 11.6" "Group enriched" "Detected in some" 8 "Plasma cells: 4.1;T-cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 115.7" "Lineage enriched" "Detected in many" 115 "T-cells: 115.7" "Group enriched" "Detected in some" 6 "Leukemia: 3.3;ovarian cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.48e-3)" "unprognostic (6.75e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-3)" "unprognostic (5.82e-2)" "unprognostic (2.79e-2)" "unprognostic (1.59e-2)" "unprognostic (4.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-4)" "unprognostic (2.77e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" TRBV6-5 "TCRBV13S1, TCRBV6S5, TRBV65" ENSG00000211721 "T cell receptor beta variable 6-5" A0A0K0K1A5 7 142450947-142451448 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 82.3" "Cell type enriched" "Detected in single" 58 "T-cells: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 133.8;T-reg: 137.9" "Lineage enriched" "Detected in many" 54 "T-cells: 137.9" "Cancer enriched" "Detected in single" 70 "Leukemia: 23.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" "unprognostic (6.42e-3)" "unprognostic (7.43e-4)" "unprognostic (1.11e-2)" "unprognostic (2.20e-3)" "unprognostic (1.38e-1)" "unprognostic (8.63e-5)" "unprognostic (1.55e-2)" "unprognostic (1.51e-3)" "unprognostic (8.72e-3)" "unprognostic (2.11e-3)" "unprognostic (7.03e-2)" "unprognostic (4.82e-1)" "prognostic unfavorable (5.40e-5)" "unprognostic (3.12e-2)" "unprognostic (4.17e-2)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 30.1" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Cancer enriched" "Detected in single" 46 "Leukemia: 13.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 2: T-cells - T-cell receptor" TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 876.8;Excitatory neurons: 384.1;Inhibitory neurons: 182.7;Muller glia cells: 158.4;Oligodendrocyte precursor cells: 101.1" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 7.2;Rhabdoid: 11.8;skin cancer: 4.4" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 47: Retina - Visual perception" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" TRPM5 "LTRPC5, MTR1" ENSG00000070985 "Transient receptor potential cation channel subfamily M member 5" Q9NZQ8 11 2404515-2423045 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.8;intestine: 3.3;pancreas: 2.4;seminal vesicle: 1.7" "Cell type enriched" "Detected in some" 5 "Distal enterocytes: 10.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 56: Neurons - Neuronal signaling" "Cluster 26: Intestinal epithelial cells - Absorption" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (6.47e-5)" "unprognostic (6.81e-4)" "unprognostic (7.90e-3)" "unprognostic (1.18e-1)" "unprognostic (1.13e-2)" "unprognostic (2.24e-2)" "unprognostic (4.75e-1)" "unprognostic (1.53e-1)" "unprognostic (2.36e-1)" "unprognostic (3.19e-1)" "unprognostic (5.07e-3)" "unprognostic (2.40e-1)" "unprognostic (5.21e-1)" "unprognostic (5.72e-2)" "unprognostic (4.91e-2)" TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Cell type enhanced" "Detected in many" "Adipocytes: 70.9;Cardiomyocytes: 19.7;Early spermatids: 20.4;Endothelial cells: 58.5;Proximal tubular cells: 18.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Neuroblastoma: 28.8;testis cancer: 99.8" "Breast - Endothelial cells, Colon - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 199.2;Hofbauer cells: 221.7;Leydig cells: 176.1;Melanocytes: 170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 584.9;Hepatocytes: 430.3;Paneth cells: 294.4;Proximal enterocytes: 294.5" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" TTC23 "FLJ12572, HCC-8" ENSG00000103852 "Tetratricopeptide repeat domain 23" Q5W5X9 15 99136323-99251223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039806, HPA040369" Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 31: Spermatocytes - Spermatogenesis" Cytosol "HPA039806: AB_10793921, HPA040369: AB_10795381" "prognostic favorable (3.17e-4)" "unprognostic (5.41e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.40e-2)" "unprognostic (6.53e-2)" "unprognostic (9.25e-3)" "unprognostic (2.56e-1)" "unprognostic (6.18e-2)" "unprognostic (1.76e-3)" "unprognostic (1.88e-1)" "unprognostic (3.24e-1)" "unprognostic (3.21e-2)" "unprognostic (1.11e-2)" "unprognostic (4.31e-1)" "unprognostic (7.99e-2)" "unprognostic (1.23e-1)" TTC24 ENSG00000187862 "Tetratricopeptide repeat domain 24" A2A3L6 1 156579723-156587719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 21.2" "Cell type enriched" "Detected in some" 9 "dendritic cells: 53.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NK-cell: 3.7;plasmacytoid DC: 12.4" "Group enriched" "Detected in many" 4 "dendritic cells: 12.4;NK-cells: 3.7" "Group enriched" "Detected in some" 16 "Leukemia: 7.1;lymphoma: 4.5" "Breast - T-cells, Lung - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029799 Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Nucleoplasm "HPA029799: AB_10601684" "unprognostic (2.43e-3)" "unprognostic (5.61e-5)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-6)" "unprognostic (6.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.42e-1)" "unprognostic (7.96e-2)" "unprognostic (4.87e-9)" "unprognostic (1.07e-2)" "unprognostic (5.19e-2)" "unprognostic (2.22e-2)" "unprognostic (9.76e-4)" TTC7B TTC7L1 ENSG00000165914 "Tetratricopeptide repeat domain 7B" Q86TV6 14 90524564-90816479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 86.0;Excitatory neurons: 115.0;Inhibitory neurons: 129.8;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 66.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.6;eosinophil: 8.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.0" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058363, HPA059577" Enhanced Supported "Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane" "HPA058363: AB_2683692, HPA059577: AB_2684069" "unprognostic (9.37e-2)" "unprognostic (4.20e-2)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.58e-1)" "unprognostic (2.67e-4)" "unprognostic (9.42e-2)" "unprognostic (2.17e-1)" "unprognostic (5.38e-2)" "unprognostic (7.60e-2)" "unprognostic (2.75e-3)" "unprognostic (2.87e-2)" "prognostic favorable (3.20e-6)" "unprognostic (2.74e-2)" "unprognostic (7.41e-2)" "unprognostic (4.48e-2)" "unprognostic (1.07e-2)" TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 170.1;monocytes: 171.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 114.6" "Group enriched" "Detected in all" 5 "granulocytes: 114.6;monocytes: 47.8" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 55: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 97.6;Fibroblasts: 68.1;granulocytes: 44.2;Langerhans cells: 30.1;Leydig cells: 46.8;Peritubular cells: 40.6;Thymic epithelial cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cancer enhanced" "Detected in many" "Sarcoma: 11.5" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350307 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 243.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm NA NA 6100000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 61: Liver - Metabolism" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: AB_2678709" "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 57: Non-specific - Translation" "Cluster 65: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 314.6;monocytes: 244.4" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 122.4" "Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 19: Macrophages - Innate immune response" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" USH1G "ANKS4A, FLJ33924, Sans" ENSG00000182040 "USH1 protein network component sans" Q495M9 17 74916083-74923256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 7.8;skin 1: 2.8" "Group enriched" "Detected in some" 4 "Early spermatids: 6.0;Late spermatids: 20.4;Muller glia cells: 11.5;Suprabasal keratinocytes: 6.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 5.6;Gallbladder cancer: 3.7;head and neck cancer: 3.4" "Prostate - Urothelial cells, Testis - Late spermatids" "Region enriched" "Detected in single" 12 "olfactory bulb: 9.9" "Not detected" "Not detected" HPA024360 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 6: Late spermatids - Spermatogenesis" "HPA024360: AB_1858660" "unprognostic (2.95e-1)" "unprognostic (6.17e-2)" "unprognostic (6.34e-4)" "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.74e-1)" "unprognostic (5.59e-4)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (3.10e-4)" "unprognostic (1.57e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-2)" USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 30.9;Excitatory neurons: 35.1;Glandular and luminal cells: 44.5;Oligodendrocyte precursor cells: 70.3;Respiratory ciliated cells: 32.5;Syncytiotrophoblasts: 65.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762, HPA027763" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Nuclear speckles" "HPA023389: AB_1858691, HPA027762: AB_10603001, HPA027763: " "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 509.9;monocytes: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 19: Macrophages - Innate immune response" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 27.2;granulocytes: 40.1;Hofbauer cells: 54.2;Kupffer cells: 29.2;Macrophages: 35.7;Microglial cells: 30.1;monocytes: 57.5;T-cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 65.3;lymphoma: 46.4;Myeloma: 67.0" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 19: Macrophages - Innate immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 969.7;Granulosa cells: 1101.8;Kupffer cells: 1041.7;Macrophages: 573.9;Oligodendrocyte precursor cells: 1575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 172.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 235.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.5;monocytes: 54.8;Proximal enterocytes: 82.4;Schwann cells: 90.3;Undifferentiated cells: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.5;monocytes: 6.7" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 4.3" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.7;Endothelial cells: 22.5;Leydig cells: 14.4;Microglial cells: 35.6;Thymic epithelial cells: 17.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 6173.1;Langerhans cells: 5043.7;Leydig cells: 5059.5;Muller glia cells: 8289.1;Schwann cells: 8855.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946056-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "skin 1: 18.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.7;Breast glandular cells: 11.4;Breast myoepithelial cells: 6.1;Club cells: 4.5;Ionocytes: 6.4;Suprabasal keratinocytes: 20.2" "Region enhanced" "Detected in single" "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 59.9;Club cells: 29.8;Collecting duct cells: 45.3;Ductal cells: 76.4;Endometrial ciliated cells: 41.4;Glandular and luminal cells: 80.8;Mucus glandular cells: 63.7;Salivary duct cells: 31.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 43.8;ovarian cancer: 40.3;testis cancer: 29.9" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 73: Prostatic glandular cells - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.5;Ionocytes: 13.1;Late spermatids: 16.4;Microglial cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4;Gastric cancer: 6.5" "Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 2: DU4475 - Unknown function" "Cluster 5: Bronchus - Unknown function" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Group enriched" "Detected in some" 4 "Early spermatids: 1.3;Extravillous trophoblasts: 4.5;Langerhans cells: 2.3;NK-cells: 2.9;Spermatocytes: 5.0;Spermatogonia: 3.6;T-cells: 4.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Cancer enriched" "Detected in single" 22 "ovarian cancer: 8.7" "Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Enzymes" "Cluster 1: T-cells - Immune response" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.2;Extravillous trophoblasts: 26.7;Fibroblasts: 4.6;Inhibitory neurons: 4.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 17.5" "Kidney - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA055048 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: Myeloma - Humoral immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA055048: AB_2682683" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 16.1;Basal keratinocytes: 30.7;Basal squamous epithelial cells: 37.4;Club cells: 37.4;Respiratory ciliated cells: 17.1;Squamous epithelial cells: 18.9;Suprabasal keratinocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 76.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Group enriched" "Detected in many" 4 "Early spermatids: 58.8;Late spermatids: 109.8;Oligodendrocyte precursor cells: 105.4" "Cancer enriched" "Detected in many" 4 "glioma: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 26.4" "Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "Golgi apparatus" "HPA015919: AB_2216211" "unprognostic (1.50e-1)" "unprognostic (7.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.15e-2)" "unprognostic (2.61e-1)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-1)" "unprognostic (3.46e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.5;Astrocytes: 157.2;Glandular and luminal cells: 140.1;Mucus glandular cells: 105.1;Serous glandular cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 13 "NK-cells: 202.0;T-cells: 209.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 14 "NK-cells: 529.3;T-cells: 240.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cancer enriched" "Detected in some" 7 "Sarcoma: 7.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: TE 441.T - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" ZBTB42 ZNF925 ENSG00000179627 "Zinc finger and BTB domain containing 42" B2RXF5 14 104800596-104804712 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "eosinophil: 5.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" HPA066961 Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA066961: AB_2685756" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (8.68e-2)" "unprognostic (1.59e-1)" "unprognostic (6.99e-2)" "unprognostic (6.67e-2)" "unprognostic (6.17e-3)" "unprognostic (2.56e-1)" "unprognostic (4.35e-1)" "unprognostic (2.70e-2)" "unprognostic (1.63e-1)" "unprognostic (3.42e-1)" "prognostic favorable (2.30e-9)" "unprognostic (1.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.58e-3)" "unprognostic (5.45e-2)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 125.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 49: Early spermatids - Spermatogenesis" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 526.4;monocytes: 928.0;NK-cells: 516.9;Oligodendrocytes: 1406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.5" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" ZFP1 "FLJ34243, ZNF475" ENSG00000184517 "ZFP1 zinc finger protein" Q6P2D0 16 75148494-75172236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044916, HPA062910" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Nucleoplasm "HPA044916: AB_2679144, HPA062910: AB_2684902" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.24e-5)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.99e-1)" "unprognostic (1.50e-1)" "unprognostic (4.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (9.80e-4)" "unprognostic (5.55e-1)" "unprognostic (6.64e-2)" "unprognostic (2.08e-1)" ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 359.0;Early spermatids: 104.3;Excitatory neurons: 97.5;Inhibitory neurons: 94.2;Oligodendrocyte precursor cells: 133.8;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skin - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" ZNF432 KIAA0798 ENSG00000256087 "Zinc finger protein 432" O94892 19 52031378-52095738 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Prostate glandular cells" "HPA052082, HPA060274, HPA065606" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 4: Non-specific - Transcription" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "HPA052082: AB_2681719, HPA060274: AB_2684238, HPA065606: AB_2685518" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (1.92e-1)" "unprognostic (7.04e-3)" "unprognostic (1.08e-2)" "unprognostic (2.41e-3)" "unprognostic (3.19e-2)" "unprognostic (2.56e-1)" "unprognostic (6.92e-2)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (5.49e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "prognostic favorable (4.11e-5)" ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 164.8;Microglial cells: 52.0;Oligodendrocyte precursor cells: 212.3;Oligodendrocytes: 98.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cancer enhanced" "Detected in many" "Leukemia: 16.7;Rhabdoid: 26.6" "Lung - Fibroblast_2, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)" ZNF57 ZNF424 ENSG00000171970 "Zinc finger protein 57" Q68EA5 19 2900898-2918473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.9;Early spermatids: 91.4;Late spermatids: 69.9;Squamous epithelial cells: 38.9;Suprabasal keratinocytes: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA061915 Approved Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Non-specific - Transcription" "Cluster 36: Spermatids - Spermatogenesis" Nucleoli "HPA061915: AB_2684635" "unprognostic (3.59e-2)" "unprognostic (1.53e-3)" "unprognostic (1.91e-2)" "unprognostic (8.86e-3)" "unprognostic (3.32e-2)" "unprognostic (3.07e-2)" "unprognostic (7.66e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.35e-1)" "unprognostic (4.04e-2)" "prognostic favorable (7.72e-4)" "unprognostic (2.34e-3)" "prognostic favorable (4.11e-9)" "unprognostic (6.26e-3)" "unprognostic (2.82e-2)" "unprognostic (7.35e-2)" "unprognostic (6.49e-3)" ZNF674 "MRX92, ZNF673B" ENSG00000251192 "Zinc finger protein 674" Q2M3X9 X 46497727-46545457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 9.2;Inhibitory neurons: 11.1;Oligodendrocyte precursor cells: 9.1;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells" "HPA031026, HPA065295" Uncertain Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 48: Non-specific - RNA binding" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA031026: AB_10602690, HPA065295: AB_2685456" "unprognostic (6.11e-4)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.30e-2)" "unprognostic (1.54e-2)" "unprognostic (3.39e-2)" "unprognostic (6.41e-5)" "unprognostic (2.74e-4)" "unprognostic (5.68e-2)" "unprognostic (2.43e-2)" "unprognostic (2.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (3.25e-4)" "unprognostic (8.45e-4)" ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 6 "Excitatory neurons: 19.3;NK-cells: 29.9;T-cells: 53.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 1: T-cells - Immune response" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)" ZNF888 ENSG00000213793 "Zinc finger protein 888" P0CJ79 19 52904417-52923481 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 19.2;dendritic cells: 28.9;Endometrial ciliated cells: 25.8;Glandular and luminal cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 4: Non-specific - Transcription" "Cluster 14: Endometrium - Transcription regulation" "prognostic unfavorable (5.28e-4)" "unprognostic (7.35e-2)" "unprognostic (7.60e-2)" "unprognostic (6.88e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (5.00e-3)" "unprognostic (5.86e-3)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (4.31e-1)" "unprognostic (2.80e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (5.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.00e-3)" ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 204.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 4: Platelets - Platelet activation" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)"