Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1264.3;Cardiomyocytes: 398.0;Endothelial cells: 864.5;Hepatocytes: 661.1;Kupffer cells: 338.8;Microglial cells: 345.7;Smooth muscle cells: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;liver cancer: 139.1;skin cancer: 83.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: Liver cancer - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.9;Fibroblasts: 204.1;Leydig cells: 99.8;Muller glia cells: 80.2" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.4;thyroid cancer: 48.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 180.4;Cardiomyocytes: 69.9;Hepatocytes: 95.2;Oligodendrocyte precursor cells: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.2" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 68: Kidney - Mixed function" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Bipolar cells: 61.0;Early spermatids: 62.3;Hepatocytes: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 7.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 70 "granulocytes: 7.0" "Cancer enhanced" "Detected in many" "liver cancer: 9.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 63: Astrocytes - Nervous system maintenance" Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.1;Fibroblasts: 37.1;Kupffer cells: 67.8;Macrophages: 23.2;Thymic epithelial cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 69: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 145.4;Endometrial stromal cells: 37.2;Extravillous trophoblasts: 45.0;Skeletal myocytes: 51.5;Syncytiotrophoblasts: 94.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bladder cancer: 38.4" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1739.4;Excitatory neurons: 3790.8;Inhibitory neurons: 2675.1;Oligodendrocyte precursor cells: 1950.0;Oligodendrocytes: 1142.7" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.0" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 890.6;Inhibitory neurons: 631.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 565.9;Excitatory neurons: 686.2;Inhibitory neurons: 720.0;Oligodendrocyte precursor cells: 1245.7;Oligodendrocytes: 559.0" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.0;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 135 "Bone cancer: 19.1" "Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 53: Connective tissue cells - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 38.5;Endothelial cells: 26.9;Fibroblasts: 77.2;Oligodendrocyte precursor cells: 33.7;Skeletal myocytes: 35.6;Smooth muscle cells: 40.6;Thymic epithelial cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 25.1" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Cell type enhanced" "Detected in many" "Astrocytes: 1066.9;Excitatory neurons: 1263.4;Horizontal cells: 536.4;Inhibitory neurons: 1036.9;Oligodendrocyte precursor cells: 476.1;Oligodendrocytes: 1275.4;Rod photoreceptor cells: 487.6" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.2;Rhabdoid: 33.5" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 203.1;Leydig cells: 61.9;Peritubular cells: 78.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 183.4;Microglial cells: 380.4;NK-cells: 145.7;Oligodendrocyte precursor cells: 167.5;Oligodendrocytes: 188.3;T-cells: 135.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 31.6" "Adipose visceral - T-cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 62: B-cells - B-cell activation" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Astrocytes: 239.1;Excitatory neurons: 262.8;Oligodendrocyte precursor cells: 322.5;Oligodendrocytes: 781.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 82.2;granulocytes: 131.6;Granulosa cells: 117.1;Microglial cells: 75.7" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 94.2;lymphoma: 34.9" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003578, HPA071036" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 62: Granulocytes - Innate immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane, Cytosol" "HPA003578: AB_1078203, HPA071036: " "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.5;Fibroblasts: 9.8;Melanocytes: 24.4;Pancreatic endocrine cells: 17.2;Suprabasal keratinocytes: 15.0;Thymic epithelial cells: 7.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 28.5;Rhabdoid: 32.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.2;Melanocytes: 78.4;Oligodendrocytes: 204.8;Peritubular cells: 48.3;Proximal tubular cells: 61.2;Schwann cells: 52.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2106.8;Inhibitory neurons: 1445.3;Oligodendrocyte precursor cells: 1395.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 17: RS4;11 - Unknown function" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 28.8;Cone photoreceptor cells: 31.0;Distal tubular cells: 31.1;Proximal tubular cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.9" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 116.7;Cholangiocytes: 165.5;Distal tubular cells: 139.9;Ductal cells: 95.6;Microglial cells: 161.5;Proximal tubular cells: 177.8" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 65.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Cytotrophoblasts: 29.8;Fibroblasts: 45.0;Syncytiotrophoblasts: 40.1" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 267.9;Gastric cancer: 194.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 62.3;Kupffer cells: 49.9;Macrophages: 36.0;monocytes: 34.7;Proximal enterocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" C11orf95 MGC3032 ENSG00000188070 "Chromosome 11 open reading frame 95" C9JLR9 11 63759892-63768775 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045002 Approved "Intermediate filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Intermediate filaments" "HPA045002: AB_2679179" "unprognostic (4.23e-3)" "unprognostic (7.24e-3)" "unprognostic (6.47e-2)" "unprognostic (9.01e-3)" "unprognostic (7.54e-2)" "unprognostic (3.89e-1)" "unprognostic (8.94e-2)" "unprognostic (3.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" "unprognostic (8.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.52e-3)" "unprognostic (1.85e-2)" "unprognostic (6.60e-2)" "unprognostic (5.68e-2)" "unprognostic (1.31e-3)" C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.8;Alveolar cells type 2: 40.2;Basal prostatic cells: 57.3;Bipolar cells: 48.3;Endometrial ciliated cells: 61.7;Horizontal cells: 43.6" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 63.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 70: Basal prostatic cells - Lipid metabolism" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 108.3;thyroid gland: 228.8" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 261.4;Club cells: 66.2;Distal tubular cells: 77.7" "Group enriched" "Detected in many" 14 "lung cancer: 64.7;thyroid cancer: 145.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "thyroid cancer: 13.9" "Colon - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Fibroblasts, Stomach - Chief cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" NA NA 1400000 "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 41: Alveolar cells - Lung function" "HPA013613: AB_1845584, HPA016934: AB_2732417" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (6.29e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (9.23e-2)" "unprognostic (2.65e-1)" "unprognostic (6.39e-2)" "unprognostic (3.25e-2)" "unprognostic (6.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (8.48e-3)" C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Group enriched" "Detected in some" 6 "Horizontal cells: 293.5;Oligodendrocyte precursor cells: 80.9;Thymic epithelial cells: 114.1" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 86.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Cholangiocyte, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Kidney - Mixed function" "Cluster 9: Neurons - Nervous system development" Vesicles Cytosol "HPA071349: " "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 17.7;Leydig cells: 22.0;Peritubular cells: 30.8;Smooth muscle cells: 21.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "Sarcoma: 7.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.7;Fibroblasts: 27.7;granulocytes: 9.9;Leydig cells: 21.3;Peritubular cells: 34.1;Smooth muscle cells: 12.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 5 "Fibroblasts: 708.6;Leydig cells: 1128.7;Theca cells: 421.0" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Neuroblastoma: 31.3" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 15: Smooth muscle cells - Muscle contraction" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 5273.7" "Cell type enriched" "Detected in many" 18 "Skeletal myocytes: 3139.5" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 9.7;Sarcoma: 6.3" "Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 53000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 27: Skeletal myocytes - Muscle contraction" "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favorable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 89.8;Oligodendrocyte precursor cells: 124.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cancer enhanced" "Detected in many" "Leukemia: 6.0;skin cancer: 8.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 291.3;Fibroblasts: 994.9;Late spermatids: 492.2;Thymic epithelial cells: 831.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "cervical cancer: 356.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Group enriched" "Detected in many" 5 "Endometrial stromal cells: 159.7;Fibroblasts: 187.7;Leydig cells: 76.7;Smooth muscle cells: 67.2;Thymic epithelial cells: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Group enriched" "Detected in many" 6 "Bone cancer: 145.3;Neuroblastoma: 37.3;Sarcoma: 72.9" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 728.7;Late spermatids: 1686.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 36: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 591.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 9 "Fibroblasts: 7818.5;Leydig cells: 5159.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Cancer enriched" "Detected in many" 4 "Leukemia: 77.2" "Liver - Kupffer cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 772.6" "Cell type enhanced" "Detected in many" "Astrocytes: 189.2;Excitatory neurons: 588.0;Horizontal cells: 96.8;Inhibitory neurons: 109.0;Microglial cells: 94.9;Oligodendrocyte precursor cells: 143.4" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.5;memory CD8 T-cell: 2.1;T-reg: 8.0" "Lineage enriched" "Detected in single" 18 "T-cells: 8.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" CHST14 "D4ST-1, D4ST1, HD4ST" ENSG00000169105 "Carbohydrate sulfotransferase 14" Q8NCH0 15 40470984-40473158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.0;Extravillous trophoblasts: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA057697, HPA071601" Enhanced Approved "Golgi apparatus" NA NA 20000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus" "HPA057697: AB_2683505, HPA071601: AB_2686425" "unprognostic (5.46e-2)" "unprognostic (9.23e-2)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-2)" "unprognostic (6.94e-2)" "unprognostic (1.70e-1)" "unprognostic (9.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.17e-2)" "unprognostic (5.85e-3)" "unprognostic (2.01e-3)" "unprognostic (1.94e-1)" "unprognostic (6.34e-2)" "unprognostic (2.25e-2)" CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.2;Excitatory neurons: 26.1;Fibroblasts: 59.3;Inhibitory neurons: 31.3;Peritubular cells: 60.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 103.1;Extravillous trophoblasts: 263.3;Granulosa cells: 133.7;Hofbauer cells: 121.7;Sertoli cells: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 17: RS4;11 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.9;Leydig cells: 34.7;Peritubular cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 123.7;granulocytes: 108.7" "Cancer enhanced" "Detected in all" "glioma: 14.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.2" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.5" "Liver - Vascular Endothelial cells, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 54000 "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Cytosol "HPA035337: AB_10601359" "unprognostic (1.23e-1)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (6.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.86e-2)" "unprognostic (4.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.04e-2)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.38e-3)" CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Muller glia cells: 78.5;Paneth cells: 37.5;Sertoli cells: 24.9" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "Neuroblastoma: 94.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 89.4;Spermatocytes: 83.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 64: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 740.2;Excitatory neurons: 832.7;Inhibitory neurons: 682.3;Oligodendrocyte precursor cells: 978.1" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 239.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 451.8;Excitatory neurons: 947.1;Inhibitory neurons: 1024.1;Late spermatids: 186.7;Oligodendrocyte precursor cells: 237.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.8;Rhabdoid: 5.0" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 170000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 101.5;Fibroblasts: 182.8;Schwann cells: 66.2;Smooth muscle cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Brain cancer: 29.5;colorectal cancer: 45.5;Sarcoma: 64.1;thyroid cancer: 21.1" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: NCI-H716 - Unknown function" "Cluster 15: Smooth muscle cells - Muscle contraction" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 129.4;Fibroblasts: 126.5;Leydig cells: 61.6;Pancreatic endocrine cells: 61.8;Schwann cells: 50.9;Smooth muscle cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 233.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 175.7;Excitatory neurons: 182.8;Fibroblasts: 155.6;Smooth muscle cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 466.3;testis cancer: 373.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 50.6" "Cell type enhanced" "Detected in many" "Astrocytes: 51.9;Excitatory neurons: 78.8;Inhibitory neurons: 69.9;Late spermatids: 82.4;Oligodendrocyte precursor cells: 110.2;Oligodendrocytes: 339.2" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.9" "Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 69.0;Inhibitory neurons: 43.3;Oligodendrocytes: 185.5;Spermatocytes: 36.3;Spermatogonia: 65.0" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" CPNE5 "COPN5, CPN5, KIAA1599" ENSG00000124772 "Copine 5" Q9HCH3 6 36740775-36839444 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4;heart muscle: 92.7" "Cell type enhanced" "Detected in many" "B-cells: 33.3;Cardiomyocytes: 35.6;Excitatory neurons: 34.6;Horizontal cells: 41.0;Oligodendrocyte precursor cells: 35.1;Plasma cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 11.3" "Region enhanced" "Detected in many" "basal ganglia: 62.4" "Group enriched" "Detected in some" 80 "memory B-cell: 51.6;naive B-cell: 26.8" "Lineage enriched" "Detected in single" 105 "B-cells: 51.6" "Group enriched" "Detected in many" 5 "lymphoma: 18.1;Myeloma: 29.2" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enhanced" "Detected in many" "basal ganglia: 103.3" "Region enhanced" "Detected in many" "basal ganglia: 135.5" HPA031369 Enhanced Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Cytosol "HPA031369: AB_10601801" "unprognostic (5.71e-3)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.73e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-3)" "unprognostic (2.45e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.00e-5)" "unprognostic (1.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.00e-1)" "unprognostic (3.57e-1)" CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 145.5;Oligodendrocytes: 282.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 349.2;Langerhans cells: 532.7;Macrophages: 248.8;monocytes: 278.7;Schwann cells: 1212.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cancer enhanced" "Detected in many" "testis cancer: 97.0" "Adipose subcutaneous - Macrophages, Colon - Fibroblasts, Liver - Kupffer cells, Lung - Macrophages, Prostate - Fibroblasts, Skin - Langerhans cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 499.4;Kupffer cells: 270.2;Macrophages: 260.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Myeloma - Humoral immune response" "Cluster 69: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 313.6;Langerhans cells: 85.7;Leydig cells: 123.5;Peritubular cells: 151.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Cancer enriched" "Detected in many" 7 "skin cancer: 71.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 297.3;Distal tubular cells: 118.2;Endothelial cells: 139.5;Fibroblasts: 456.2;Smooth muscle cells: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 47.1;testis cancer: 63.6" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.6;Leydig cells: 197.5;Peritubular cells: 219.1;Proximal enterocytes: 701.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Fibroblasts: 75.3;Leydig cells: 89.1;Melanocytes: 102.8;Sertoli cells: 41.5;Smooth muscle cells: 69.9" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Neuroblastoma: 93.0;skin cancer: 107.6" "Breast - Endothelial cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 65: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 34.6;Collecting duct cells: 45.3;Distal tubular cells: 37.3;Muller glia cells: 41.6;Proximal tubular cells: 44.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.6;ovarian cancer: 5.6" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1265.2;Fibroblasts: 6648.3;Leydig cells: 6373.4;Peritubular cells: 1909.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cancer enriched" "Detected in all" 4 "Rhabdoid: 698.3" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 126.8;Intestinal goblet cells: 38.1;Oligodendrocyte precursor cells: 69.3;Oligodendrocytes: 39.9;Paneth cells: 35.8;Undifferentiated cells: 36.6" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 50: Enterocytes - Absorption" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 889.2;Muller glia cells: 1843.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cancer enhanced" "Detected in many" "Brain cancer: 325.0" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 68: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" DMC1 LIM15 ENSG00000100206 "DNA meiotic recombinase 1" Q14565 22 38518948-38570204 "Predicted intracellular proteins" "Cell cycle, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.3" "Cell type enriched" "Detected in many" 7 "Spermatocytes: 116.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001232, CAB015397" Enhanced Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB015397: AB_629406, HPA001232: AB_1078683" "unprognostic (1.29e-2)" "unprognostic (3.11e-3)" "unprognostic (4.48e-3)" "unprognostic (5.71e-2)" "unprognostic (6.43e-2)" "unprognostic (2.22e-1)" "unprognostic (8.22e-2)" "unprognostic (2.61e-2)" "unprognostic (4.23e-2)" "unprognostic (3.99e-3)" "unprognostic (7.40e-3)" "unprognostic (1.00e-2)" "unprognostic (2.16e-4)" "unprognostic (3.94e-1)" "unprognostic (2.79e-1)" "unprognostic (7.27e-2)" "unprognostic (2.99e-1)" DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 107.2;Excitatory neurons: 48.9;Horizontal cells: 34.6;Inhibitory neurons: 77.7;Muller glia cells: 57.0;Oligodendrocyte precursor cells: 55.8" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.6" "Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 32: Neurons - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 187.1;Excitatory neurons: 233.1;Inhibitory neurons: 253.0;Oligodendrocyte precursor cells: 170.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.4;testis cancer: 7.6" "Kidney - Proximal tubular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 6 "Fibroblasts: 253.9;Leydig cells: 165.5;Peritubular cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.8;skin cancer: 2.4;thyroid cancer: 5.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1616.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in many" "Adipocytes: 383.0;Oligodendrocytes: 346.6" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" DSCAML1 KIAA1132 ENSG00000177103 "DS cell adhesion molecule like 1" Q8TD84 11 117427772-117817525 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.0;retina: 20.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 81.1;Excitatory neurons: 175.9;Inhibitory neurons: 227.1;Oligodendrocyte precursor cells: 337.9;Oligodendrocytes: 439.2;Rod photoreceptor cells: 163.1" "Cancer enhanced" "Detected in some" "glioma: 1.9;renal cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.5;Uterine cancer: 5.3" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035230 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 32: Neurons - Synaptic function" "HPA035230: AB_2674527" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" "unprognostic (1.07e-2)" "unprognostic (6.27e-5)" "unprognostic (8.48e-2)" "unprognostic (1.56e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (7.96e-2)" "unprognostic (2.89e-2)" "unprognostic (2.39e-3)" "unprognostic (8.37e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-2)" DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 83.2;Extravillous trophoblasts: 87.3;Oligodendrocyte precursor cells: 107.8;Oligodendrocytes: 98.3;Theca cells: 74.3" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 366.4;Late spermatids: 777.3;Spermatocytes: 190.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 22.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 107.5;Fibroblasts: 105.1;Melanocytes: 92.3;Suprabasal keratinocytes: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 171.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 57.3;Hepatocytes: 47.5;Leydig cells: 123.8;Peritubular cells: 72.2;Smooth muscle cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 256.8" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 537.7;Oligodendrocytes: 2001.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 123.7;Kidney cancer: 125.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020415, HPA022122" Approved Uncertain "Plasma membrane" "Secreted to blood" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA020415: AB_2670434, HPA022122: " "unprognostic (9.93e-3)" "unprognostic (2.38e-1)" "unprognostic (2.71e-2)" "unprognostic (8.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (9.19e-2)" "unprognostic (6.64e-3)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.28e-3)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 348.1;Cytotrophoblasts: 1355.8;Fibroblasts: 293.4;Syncytiotrophoblasts: 835.0;Thymic epithelial cells: 783.2" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.0;Early spermatids: 43.4;Late spermatids: 50.4;Leydig cells: 164.1;Rod photoreceptor cells: 39.4;Sertoli cells: 38.7;Smooth muscle cells: 48.1" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 38.6" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: Bone cancer - Transcription" "Cluster 72: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.1;Fibroblasts: 140.8;Leydig cells: 109.7;Peritubular cells: 137.6;Skeletal myocytes: 116.8;Smooth muscle cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 67.3;Sarcoma: 195.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 774.7;Hofbauer cells: 898.0;Langerhans cells: 2220.9;Macrophages: 697.4;Melanocytes: 1260.9;monocytes: 1112.9" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 75: Myeloid cells - Innate immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 163.6;kidney: 90.0" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 607.5" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.5;Kidney cancer: 12.5;testis cancer: 5.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Late spermatids: 349.9;Microglial cells: 422.3;Muller glia cells: 397.8;Rod photoreceptor cells: 1231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 44: Photoreceptor cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 69.6;Inhibitory neurons: 103.5;Microglial cells: 100.3;Oligodendrocytes: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 32: Neurons - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in many" 5 "Excitatory neurons: 136.5;Inhibitory neurons: 167.7" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.5;Sarcoma: 27.4" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 99.5;Hepatocytes: 172.8;Leydig cells: 221.9;Peritubular cells: 237.0" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "liver cancer: 18.0" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.2;Early spermatids: 22.0;Endometrial stromal cells: 16.4;Salivary duct cells: 21.8;Sertoli cells: 27.6;Smooth muscle cells: 84.7" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.2;testis cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 41: Non-specific - Cilium assembly" "Cluster 72: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 250.5;Bipolar cells: 131.1;Excitatory neurons: 124.5;Inhibitory neurons: 111.4;Oligodendrocyte precursor cells: 97.7;Oligodendrocytes: 74.1" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 4 "Sarcoma: 40.6" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010529, HPA010639, HPA013434" Approved Approved Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 35: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "Nucleoli, Cytosol" "HPA010529: , HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 23.5;Endothelial cells: 30.5;Fibroblasts: 25.2;Inhibitory neurons: 33.9;Microglial cells: 22.8;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Bone cancer: 19.0" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 37: Neurons - Neuronal signaling" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 642.8;Endometrial stromal cells: 621.5;Extravillous trophoblasts: 725.8;Fibroblasts: 1239.4;Syncytiotrophoblasts: 1320.1" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 88.4;Endometrial stromal cells: 85.2;Fibroblasts: 411.5;Leydig cells: 178.2;Peritubular cells: 218.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Fibroblasts: 214.7;Leydig cells: 626.8;Peritubular cells: 787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cancer enhanced" "Detected in many" "cervical cancer: 21.2" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.0;Distal tubular cells: 46.6;Endometrial stromal cells: 41.8;Fibroblasts: 162.4;Leydig cells: 76.4;Smooth muscle cells: 59.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder cancer: 6.4;Bone cancer: 7.8;Brain cancer: 6.2;head and neck cancer: 8.9;Sarcoma: 13.5" "Prostate - Fibroblasts, Skin - Endothelial cells" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 133.2;Endometrial stromal cells: 56.9;Fibroblasts: 58.1;Late spermatids: 49.8;Leydig cells: 66.1;Peritubular cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 270.8;Excitatory neurons: 542.5;Inhibitory neurons: 313.2;Leydig cells: 214.3;Microglial cells: 421.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 23.8" "Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Cell type enhanced" "Detected in some" "Endothelial cells: 18.6;Fibroblasts: 18.4;Microglial cells: 6.4;Smooth muscle cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 12.5" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 20.6;Neuroblastoma: 12.7" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 68: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.3;Leydig cells: 59.5;Muller glia cells: 60.1;Schwann cells: 246.7;Skeletal myocytes: 78.2" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 91.1;Leydig cells: 239.8;Muller glia cells: 122.0;Peritubular cells: 355.1;Sertoli cells: 270.9;Theca cells: 123.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cancer enhanced" "Detected in many" "Neuroblastoma: 146.2" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;retina: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 211.6;Inhibitory neurons: 324.6;Oligodendrocyte precursor cells: 944.9;Oligodendrocytes: 375.9" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 9.9;Neuroblastoma: 11.5" "Lung - Alveolar cells type 1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" "HPA060775: AB_2684358" "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 125.4;Gastric mucus-secreting cells: 97.8;Thymic epithelial cells: 89.0" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 12.6;choroid plexus: 7.4;heart muscle: 8.8;liver: 21.5;pituitary gland: 23.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.4;Cardiomyocytes: 4.9;Muller glia cells: 3.1;Smooth muscle cells: 4.2" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007034, HPA007093" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 311.1;Fibroblasts: 168.2;granulocytes: 138.7;Langerhans cells: 122.7;Smooth muscle cells: 204.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 72: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 29.5;Fibroblasts: 64.4;Thymic epithelial cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cancer enhanced" "Detected in many" "Brain cancer: 40.9" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.2;Breast glandular cells: 27.4;Fibroblasts: 49.5;Hepatocytes: 34.8;Oligodendrocyte precursor cells: 87.1;Schwann cells: 25.2" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Kidney cancer: 60.9" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 211.3;Langerhans cells: 274.5;Macrophages: 158.1;Serous glandular cells: 325.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Not detected" "Not detected" "Adipose visceral - T-cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" HPA023262 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 36: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 38.3;Fibroblasts: 9.8;Leydig cells: 25.1;Peritubular cells: 29.6;Theca cells: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.6;Leydig cells: 23.0;Peritubular cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 68: Kidney - Mixed function" "Cluster 15: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 30.9;Early spermatids: 43.4;Fibroblasts: 49.8;Leydig cells: 56.8;Peritubular cells: 52.8;Thymic epithelial cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.2;Excitatory neurons: 329.3;Inhibitory neurons: 484.6;Oligodendrocyte precursor cells: 662.3;Rod photoreceptor cells: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 37.9;testis cancer: 39.5" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013601, HPA017671" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles" "HPA013601: , HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 743.2;choroid plexus: 180.7;retina: 207.7" "Cell type enhanced" "Detected in many" "Astrocytes: 613.6;Melanocytes: 674.0;Muller glia cells: 1537.2;Oligodendrocyte precursor cells: 390.9;Oligodendrocytes: 1393.9;Schwann cells: 1021.2" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 220 "plasmacytoid DC: 77.7" "Lineage enriched" "Detected in single" 268 "dendritic cells: 77.7" "Group enriched" "Detected in many" 5 "Brain cancer: 39.0;Rhabdoid: 47.9;skin cancer: 66.6;testis cancer: 41.9" "Colon - Enteric glia cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3;Extravillous trophoblasts: 258.2;Fibroblasts: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.5;granulocytes: 43.5;Leydig cells: 149.6;Muller glia cells: 200.3;Peritubular cells: 127.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 11 "Bone cancer: 2.9;head and neck cancer: 1.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 68: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 42.8;Endometrial stromal cells: 45.2;Fibroblasts: 27.2;Late spermatids: 32.3;Oligodendrocytes: 57.9;Thymic epithelial cells: 44.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 866.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.1;Fibroblasts: 21.6;Inhibitory neurons: 22.0;Muller glia cells: 28.2;Smooth muscle cells: 62.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 105.6;Rhabdoid: 240.2" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 53: Connective tissue cells - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.4;Excitatory neurons: 79.4;Inhibitory neurons: 74.4;Oligodendrocytes: 22.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.7" "Liver - Hepatic stellate cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" HS6ST2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626016-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;kidney: 13.9;ovary: 14.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.2;Excitatory neurons: 37.0;Inhibitory neurons: 43.3;Leydig cells: 61.9;Oligodendrocyte precursor cells: 52.0;Peritubular cells: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus" "Plasma membrane" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;choroid plexus: 5.6" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 80.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.5" "Prostate - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 247.5;Granulosa cells: 673.5;Muller glia cells: 340.9;Thymic epithelial cells: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 59: Fibroblasts - Metabolism" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Group enriched" "Detected in many" 5 "Fibroblasts: 145.2;Leydig cells: 44.7;Peritubular cells: 41.0;Theca cells: 64.5" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 28.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: RS4;11 - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" HVCN1 "Hv1, MGC15619, VSOP" ENSG00000122986 "Hydrogen voltage gated channel 1" Q96D96 12 110627841-110704950 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 162.1;lymphoid tissue: 72.9" "Cell type enhanced" "Detected in many" "B-cells: 182.2;dendritic cells: 70.3;Early spermatids: 85.7;Hofbauer cells: 63.7;Late spermatids: 72.5;Spermatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Leukemia: 31.5;lymphoma: 38.8;Myeloma: 32.1" "Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039329 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" "HPA039329: AB_10674284" "unprognostic (3.43e-2)" "unprognostic (6.32e-3)" "unprognostic (7.05e-2)" "unprognostic (1.54e-2)" "unprognostic (4.62e-3)" "unprognostic (3.89e-2)" "unprognostic (1.96e-1)" "unprognostic (5.85e-3)" "unprognostic (2.40e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-2)" "unprognostic (5.67e-2)" "unprognostic (3.35e-3)" "unprognostic (4.82e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 323.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 228.9;Inhibitory neurons: 237.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "amygdala: 194.3;basal ganglia: 212.9;cerebral cortex: 323.4;hippocampal formation: 320.5;white matter: 109.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 56: Ciliated cells - Cilium assembly" Microtubules Cytosol "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in some" "Astrocytes: 18.0;Cone photoreceptor cells: 12.1;Leydig cells: 34.1;Melanocytes: 17.4;Microglial cells: 13.7;Oligodendrocyte precursor cells: 16.8;Rod photoreceptor cells: 13.4;Skeletal myocytes: 21.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.4" "Adipose subcutaneous - Adipose progenitor cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Group enriched" "Detected in some" 4 "Adipocytes: 76.8;Cytotrophoblasts: 118.5;Extravillous trophoblasts: 253.1;Leydig cells: 165.1;Syncytiotrophoblasts: 177.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 577.1;Sarcoma: 553.6" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007556 Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 41: Non-specific - Cilium assembly" "Cluster 54: Extravillous trophoblasts - Unknown function" "Golgi apparatus" "HPA007556: AB_2667860" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 124.4;dendritic cells: 118.0;Kupffer cells: 189.7;Langerhans cells: 109.0;monocytes: 69.2;NK-cells: 87.6;Plasma cells: 76.4;T-cells: 71.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 24 "Leukemia: 31.6;lymphoma: 39.9;Myeloma: 42.3;skin cancer: 16.3" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 62.0;Early spermatids: 19.5;Excitatory neurons: 17.3;Late spermatids: 37.4;Muller glia cells: 23.5;Oligodendrocyte precursor cells: 19.7;Skeletal myocytes: 28.7" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 78.3;Inhibitory neurons: 127.4;Late spermatids: 92.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "skin cancer: 72.2;testis cancer: 181.5" "Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 194.0;Fibroblasts: 156.8;Leydig cells: 219.8;Peritubular cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 82.7;monocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 216.7;Inhibitory neurons: 234.2;Oligodendrocyte precursor cells: 297.5" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.2" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 37: Neurons - Neuronal signaling" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.8;Bipolar cells: 3.4;Fibroblasts: 6.5;Horizontal cells: 9.6;Skeletal myocytes: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.5" "Kidney - T-cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 61.4;Microglial cells: 65.7;Oligodendrocytes: 128.0" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 20.8;skin cancer: 27.6" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 5 "granulocytes: 72.9;NK-cells: 126.9;T-cells: 96.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 390.9;MAIT T-cell: 461.3" "Lineage enriched" "Detected in all" 22 "T-cells: 461.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.2;Early spermatids: 108.7;Excitatory neurons: 133.7;Inhibitory neurons: 90.6;Late spermatids: 85.1;Spermatocytes: 50.0" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: Non-specific - Cilium assembly" "Cluster 38: Neurons - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" LINGO2 "LERN3, LRRN6C" ENSG00000174482 "Leucine rich repeat and Ig domain containing 2" Q7L985 9 27948078-28670286 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.5;smooth muscle: 8.8" "Group enriched" "Detected in some" 30 "Excitatory neurons: 1566.5;Inhibitory neurons: 960.6" "Cancer enhanced" "Detected in single" "melanoma: 0.8" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 9 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 9 "NK-cells: 1.0" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 10.4" "Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA016633, CAB025361" Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "CAB025361: , HPA016633: AB_1853362" "unprognostic (1.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-4)" "unprognostic (9.86e-4)" "unprognostic (7.55e-3)" "unprognostic (2.67e-6)" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.08e-2)" "unprognostic (2.30e-2)" "unprognostic (1.95e-4)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 13 "Excitatory neurons: 862.2;Inhibitory neurons: 568.8;Oligodendrocyte precursor cells: 283.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.1" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 38: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Host-virus interaction" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 320.3;Leydig cells: 234.3;Peritubular cells: 183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.2;Granulosa cells: 67.2;Leydig cells: 110.8;Peritubular cells: 34.5;Sertoli cells: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cancer enhanced" "Detected in many" "Brain cancer: 57.1;Sarcoma: 73.1" "Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.9;Early spermatids: 178.8;Endometrial ciliated cells: 37.8;Respiratory ciliated cells: 72.9;Spermatocytes: 90.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 727.9;monocytes: 143.5;Oligodendrocyte precursor cells: 246.0;Skeletal myocytes: 250.4" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.2;skin cancer: 3.2" "Breast - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 41: Alveolar cells - Lung function" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" LRRN3 "FIGLER5, FLJ11129, NLRR3" ENSG00000173114 "Leucine rich repeat neuronal 3" Q9H3W5 7 111091006-111125454 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.2;thyroid gland: 19.6" "Cell type enhanced" "Detected in some" "Astrocytes: 45.5;Cardiomyocytes: 30.9;Excitatory neurons: 80.0;Horizontal cells: 39.1;Inhibitory neurons: 45.3;Leydig cells: 58.5;Oligodendrocyte precursor cells: 58.7" "Group enriched" "Detected in many" 7 "glioma: 17.5;thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 32.5;naive CD8 T-cell: 30.9" "Lineage enriched" "Detected in single" 70 "T-cells: 32.5" "Group enriched" "Detected in some" 5 "Neuroblastoma: 52.4;Sarcoma: 13.3;testis cancer: 13.6" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043820, HPA046792" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA043820: AB_2678687, HPA046792: AB_2679810" "unprognostic (4.93e-2)" "unprognostic (4.55e-2)" "unprognostic (5.92e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-2)" "unprognostic (4.78e-3)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.84e-2)" "unprognostic (4.85e-3)" "unprognostic (1.08e-2)" "unprognostic (3.29e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (7.23e-2)" LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 10.9;Fibroblasts: 51.3;Leydig cells: 27.5;Melanocytes: 26.1;Peritubular cells: 17.4" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.1" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 46: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.6;Leydig cells: 975.0;Peritubular cells: 618.8;Schwann cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Group enriched" "Detected in many" 10 "Endometrial stromal cells: 990.9;Fibroblasts: 1398.8;Leydig cells: 414.2;Smooth muscle cells: 491.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 221.2" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 257.7;Schwann cells: 274.2;Theca cells: 310.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.5;Inhibitory neurons: 51.8;Langerhans cells: 101.5;Oligodendrocyte precursor cells: 65.9;Syncytiotrophoblasts: 108.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 28: Cytotrophoblasts - Unknown function" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 238.8;Fibroblasts: 59.2;Granulosa cells: 89.6;Leydig cells: 55.4;Peritubular cells: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Fibroblasts: 596.9;Peritubular cells: 231.7;Smooth muscle cells: 172.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cancer enhanced" "Detected in many" "Bone cancer: 116.5;Neuroblastoma: 110.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 2300.4" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.5" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 38: Neurons - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 223.5;Extravillous trophoblasts: 531.3;Fibroblasts: 756.3;Leydig cells: 338.9;Peritubular cells: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 849.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 10.5;Fibroblasts: 17.9;Leydig cells: 12.7;NK-cells: 10.6;Peritubular cells: 22.3;Thymic epithelial cells: 41.3" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cancer enhanced" "Detected in some" "Sarcoma: 2.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" MOB3B "C9orf35, FLJ13204, MOB1D, MOBKL2B" ENSG00000120162 "MOB kinase activator 3B" Q86TA1 9 27325209-27529814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5;myeloid DC: 2.7;naive B-cell: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 13.2" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057744 Uncertain "Intermediate filaments,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments, Cytosol" "HPA057744: " "unprognostic (6.96e-3)" "unprognostic (9.60e-2)" "unprognostic (5.10e-3)" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (1.02e-1)" "unprognostic (1.87e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (7.57e-3)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "prognostic favorable (2.33e-10)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.99e-2)" MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 59.8;Fibroblasts: 123.2;Late spermatids: 91.7;Leydig cells: 73.3;Peritubular cells: 96.6;Theca cells: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 100.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 150.8;Extravillous trophoblasts: 294.8;Fibroblasts: 183.8;Leydig cells: 169.3;Peritubular cells: 176.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 623.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Liver - Vascular Endothelial cells, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 59: Proximal enterocytes - Transmembrane transport" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" NACAD KIAA0363 ENSG00000136274 "NAC alpha domain containing" O15069 7 45080437-45088969 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.2;pituitary gland: 24.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 19.9;Oligodendrocytes: 21.8;Peritubular cells: 12.2;Sertoli cells: 16.6" "Group enriched" "Detected in many" 7 "glioma: 12.1;testis cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Brain cancer: 6.0;Neuroblastoma: 22.5;testis cancer: 6.7" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020981, HPA079208" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Nucleoplasm "HPA020981: AB_2670549, HPA079208: " "unprognostic (5.54e-6)" "unprognostic (1.89e-1)" "unprognostic (8.55e-4)" "unprognostic (7.06e-3)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.61e-1)" "unprognostic (6.91e-2)" "unprognostic (1.16e-1)" "unprognostic (4.17e-2)" "unprognostic (3.17e-2)" "unprognostic (8.17e-3)" "unprognostic (2.76e-2)" "unprognostic (7.72e-3)" "unprognostic (2.72e-3)" "unprognostic (9.22e-2)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.4;retina: 40.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 37.9;Excitatory neurons: 27.5;Horizontal cells: 53.2;Inhibitory neurons: 55.6" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cancer enhanced" "Detected in many" "testis cancer: 20.7" "Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA026075 Uncertain Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 37: Neurons - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli" "HPA026075: AB_1854301" "unprognostic (7.18e-2)" "unprognostic (1.81e-2)" "unprognostic (9.26e-2)" "unprognostic (4.83e-4)" "unprognostic (3.06e-1)" "unprognostic (1.28e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.75e-3)" "unprognostic (5.01e-2)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-4)" NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.9;Inhibitory neurons: 158.2;Oligodendrocyte precursor cells: 683.5;Oligodendrocytes: 212.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 854.7;Excitatory neurons: 1451.5;Inhibitory neurons: 738.0;Microglial cells: 519.9;Oligodendrocyte precursor cells: 752.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.6" "Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 38: Neurons - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.0;Alveolar cells type 2: 42.5;Bipolar cells: 64.3;Early spermatids: 157.2;Late spermatids: 266.5" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 51: Myeloma - Humoral immune response" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1939.5;Inhibitory neurons: 1226.2;Oligodendrocyte precursor cells: 695.6;Oligodendrocytes: 417.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 38: Neurons - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 56.9;Endometrial stromal cells: 26.7;Fibroblasts: 22.3;Smooth muscle cells: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.6" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 72: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 753.1;Oligodendrocyte precursor cells: 581.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 26.0;Fibroblasts: 43.4;Microglial cells: 19.2;Smooth muscle cells: 23.2;Theca cells: 33.9;Thymic epithelial cells: 24.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.2" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" NIPSNAP3B FLJ11275 ENSG00000165028 "Nipsnap homolog 3B" Q9BS92 9 104764129-104777764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.4;tongue: 19.5" "Cell type enhanced" "Detected in many" "Adipocytes: 16.3;Cardiomyocytes: 35.1;Microglial cells: 16.4;Skeletal myocytes: 27.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" HPA042491 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 77: Cardiomyocytes - Muscle contraction" "HPA042491: AB_2678023" "unprognostic (1.72e-2)" "unprognostic (1.47e-2)" "unprognostic (9.76e-2)" "unprognostic (1.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (1.41e-3)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (4.25e-5)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (5.61e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (4.81e-2)" NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 151.5;Proximal tubular cells: 85.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 34.5;Excitatory neurons: 68.2;Inhibitory neurons: 67.3;Microglial cells: 33.7;Oligodendrocyte precursor cells: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 32: Neurons - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 108.9;Fibroblasts: 181.8;Leydig cells: 166.5;Peritubular cells: 203.7;Thymic epithelial cells: 677.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 21.3" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 15: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 14.1;Fibroblasts: 46.2;Leydig cells: 42.3;Peritubular cells: 39.0;Smooth muscle cells: 18.9;Thymic epithelial cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.2;Fibroblasts: 210.9;Leydig cells: 78.1;Smooth muscle cells: 69.8;Theca cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cancer enhanced" "Detected in many" "Bone cancer: 155.0;testis cancer: 143.3" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 321.4;Distal enterocytes: 166.2;monocytes: 243.3;Proximal enterocytes: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells, Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 75: Myeloid cells - Innate immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 68.2;Fibroblasts: 53.1;Leydig cells: 39.2;Peritubular cells: 57.2;Smooth muscle cells: 30.7;Theca cells: 19.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6;testis cancer: 38.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.2;Early spermatids: 10.8;Peritubular cells: 7.7;Skeletal myocytes: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.2" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.3;Cholangiocytes: 7.7;Endometrial stromal cells: 8.4;Fibroblasts: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 52: Endometrial stromal cells - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.8;Endometrial stromal cells: 8.3;Fibroblasts: 9.3;Horizontal cells: 6.4;Peritubular cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear membrane" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Early spermatids: 40.8;Late spermatids: 29.5;Spermatocytes: 20.8" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" PCDHB9 "PCDH-BETA9, PCDH3H" ENSG00000177839 "Protocadherin beta 9" Q9Y5E1 5 141187127-141191541 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Bipolar cells: 17.3;Horizontal cells: 12.8" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.6" "Lung - Fibroblast_1, Prostate - Fibroblasts" HPA013445 Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" "HPA013445: AB_1855054" "unprognostic (1.85e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-1)" "unprognostic (8.97e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.12e-1)" "unprognostic (6.78e-3)" "unprognostic (1.34e-2)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (1.86e-4)" "unprognostic (1.71e-1)" "unprognostic (9.80e-2)" "unprognostic (1.17e-1)" "unprognostic (8.01e-2)" PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.3;Bipolar cells: 7.6;Fibroblasts: 11.8;Serous glandular cells: 8.6;Skeletal myocytes: 7.9;Thymic epithelial cells: 11.0" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 508.7;Fibroblasts: 353.8;Leydig cells: 145.9;Smooth muscle cells: 366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 216.0;Neuroblastoma: 221.5;Sarcoma: 153.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.8;Extravillous trophoblasts: 68.6;Fibroblasts: 180.5;Syncytiotrophoblasts: 258.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Fibroblasts, Kidney - Podocytes, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 183.8;Inhibitory neurons: 79.5;Oligodendrocyte precursor cells: 143.0;Proximal enterocytes: 151.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 2447.1;neutrophil: 626.3" "Lineage enriched" "Detected in all" 18 "granulocytes: 2447.1" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 290000 "Cluster 41: Basophils - Cellular respiration" "Cluster 45: Intestine - Brush border" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.9;Fibroblasts: 7.3;granulocytes: 12.6;Langerhans cells: 14.1;Leydig cells: 6.9;Microglial cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1011.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 48.0" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: Skin cancer - Membrane components" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 374.7;Fibroblasts: 250.2;Leydig cells: 430.4;Oligodendrocyte precursor cells: 478.5;Peritubular cells: 384.7" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 76.7;thyroid cancer: 37.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 139.1;Leydig cells: 161.7;Peritubular cells: 206.1;Sertoli cells: 522.4;Smooth muscle cells: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 30.9;testis cancer: 38.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.8;Microglial cells: 121.3;Oligodendrocyte precursor cells: 491.5;Oligodendrocytes: 319.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.8" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Group enriched" "Detected in many" 5 "Fibroblasts: 173.6;Leydig cells: 203.7;Oligodendrocytes: 63.6;Peritubular cells: 144.5" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cancer enriched" "Detected in some" 8 "Kidney cancer: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 130.8;Inhibitory neurons: 138.3;Langerhans cells: 264.8;Microglial cells: 175.1;Oligodendrocyte precursor cells: 520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 8.7;Spermatogonia: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.3;Leukemia: 11.4" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 20: Airway & Pancreas - Proteolysis" "Nucleoplasm, Mitochondria" "HPA036587: AB_2732473, HPA036588: AB_10673502, HPA057508: AB_2683452" "unprognostic (1.43e-1)" "unprognostic (9.46e-2)" "unprognostic (2.59e-3)" "unprognostic (2.22e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-3)" "unprognostic (1.96e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-4)" "unprognostic (6.89e-2)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Adipocytes: 202.7;Fibroblasts: 744.0;Leydig cells: 848.0;Peritubular cells: 637.9;Smooth muscle cells: 456.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" PLCL2 "KIAA1092, PLCE2" ENSG00000154822 "Phospholipase C like 2" Q9UPR0 3 16802651-17090604 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 27.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 209.5;Extravillous trophoblasts: 91.5;Inhibitory neurons: 159.7;Microglial cells: 121.3;Oligodendrocyte precursor cells: 116.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 9.6;Myeloma: 8.8" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047616, HPA061728" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "HPA047616: AB_2680105, HPA061728: " "unprognostic (2.95e-2)" "unprognostic (8.09e-2)" "unprognostic (3.96e-2)" "unprognostic (6.35e-2)" "unprognostic (1.59e-1)" "unprognostic (3.83e-3)" "unprognostic (1.83e-1)" "unprognostic (9.31e-2)" "unprognostic (3.22e-2)" "unprognostic (8.72e-2)" "unprognostic (5.93e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.98e-10)" "unprognostic (2.01e-1)" "unprognostic (1.78e-1)" "unprognostic (2.70e-1)" "unprognostic (9.97e-2)" PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 490.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 362.5;Fibroblasts: 403.1;Leydig cells: 881.4;Peritubular cells: 311.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 64.2" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1473.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 181.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1468.6;Oligodendrocytes: 443.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Fibroblasts: 158.8;Leydig cells: 273.8;Peritubular cells: 262.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cancer enhanced" "Detected in some" "Sarcoma: 3.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102798976 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.9" "Group enriched" "Detected in many" 5 "NK-cells: 3.9;T-cells: 2.4" "Cancer enhanced" "Detected in all" "Kidney cancer: 67.6" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 44000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" PRDM5 PFM2 ENSG00000138738 "PR/SET domain 5" Q9NQX1 4 120684919-120922870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 49.7;Early spermatids: 82.9;Inhibitory neurons: 31.2;Late spermatids: 32.0;Oligodendrocyte precursor cells: 50.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "eosinophil: 7.5;neutrophil: 5.4" "Lineage enriched" "Detected in single" 32 "granulocytes: 7.5" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051406 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 51: Myeloma - Humoral immune response" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "Nucleoli, Nuclear bodies" Nucleoplasm "HPA051406: AB_2681472" "unprognostic (7.74e-2)" "unprognostic (8.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.09e-1)" "unprognostic (7.20e-2)" "unprognostic (9.30e-2)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "unprognostic (5.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.29e-2)" "unprognostic (4.13e-1)" "unprognostic (3.00e-2)" "unprognostic (4.91e-4)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.56e-3)" PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 695.3;Microglial cells: 117.7;Oligodendrocyte precursor cells: 404.3;Oligodendrocytes: 209.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 6.8;ovarian cancer: 3.3;Uterine cancer: 4.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 63: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 60.8;Excitatory neurons: 303.3;Inhibitory neurons: 119.3;Microglial cells: 62.9;Oligodendrocyte precursor cells: 109.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 144.4;Granulosa cells: 679.6;Theca cells: 204.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 21.3;testis cancer: 22.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Approved Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 17: Granulosa cells - Transcription regulation" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "retina: 641.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 274.0;Rod photoreceptor cells: 451.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4;Sarcoma: 1.5" "Prostate - Fibroblasts" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 47: Retina - Visual perception" "Cluster 44: Photoreceptor cells - Visual perception" "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 39 "Muller glia cells: 336.3" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Group enriched" "Detected in many" 5 "Bone cancer: 40.4;Brain cancer: 17.0;testis cancer: 17.9" "Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: Bone cancer - Transcription" "Cluster 68: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 131.9;Oligodendrocyte precursor cells: 106.9;Oligodendrocytes: 139.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 96.1" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 292.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 64: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "CAB004076, HPA031335, CAB080153, CAB080155, CAB080157" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 72: Smooth muscle cells - ECM organization" Cytosol Nucleoplasm "CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in some" "Club cells: 22.3;Collecting duct cells: 11.8;Fibroblasts: 27.2;Inhibitory neurons: 10.1;Late spermatids: 11.1;Microglial cells: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 72.0" "Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Extravillous trophoblasts: 1885.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 54: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2400.4;liver: 1994.6;pancreas: 1482.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 2599.1;Muller glia cells: 678.5;Thymic epithelial cells: 625.0;Undifferentiated cells: 551.2" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 565.3" "Lung - Fibroblast_1, Pancreas - Exocrine glandular cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 75000000 460000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 68: Kidney - Mixed function" "Cluster 29: Hepatocytes - Metabolism" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 218.0;Inhibitory neurons: 398.2;Microglial cells: 86.7;Oligodendrocytes: 373.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Cell type enhanced" "Detected in many" "Ductal cells: 937.0;Endometrial stromal cells: 1067.0;Exocrine glandular cells: 869.9;Granulosa cells: 5685.6;Theca cells: 2489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 282.2" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Leydig cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: DU4475 - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 55.3;Fibroblasts: 112.2;Leydig cells: 38.9;Pancreatic endocrine cells: 60.1;Peritubular cells: 43.0;Smooth muscle cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cancer enhanced" "Detected in all" "Bone cancer: 129.1;Sarcoma: 126.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.3;Inhibitory neurons: 69.6;Oligodendrocyte precursor cells: 77.0;Oligodendrocytes: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 129.4;Excitatory neurons: 173.7;Inhibitory neurons: 138.7;Macrophages: 81.6;Microglial cells: 74.8;Oligodendrocytes: 174.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 496.8;Late spermatids: 1667.0" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 6: Late spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.5;Astrocytes: 170.5;Endothelial cells: 70.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;skin cancer: 36.2" "Heart muscle - Fibroblasts, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" RIMS4 "C20orf190, dJ781B1.3" ENSG00000101098 "Regulating synaptic membrane exocytosis 4" Q9H426 20 44751808-44810546 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.9" "Group enriched" "Detected in some" 4 "Granulosa cells: 106.8;Horizontal cells: 34.6;Sertoli cells: 38.7" "Cancer enhanced" "Detected in many" "breast cancer: 6.6;glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 23.3" "Breast - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060928 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA060928: AB_2684387" "unprognostic (1.54e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (9.46e-2)" "unprognostic (2.97e-1)" "unprognostic (1.90e-2)" "unprognostic (4.63e-3)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (4.21e-3)" "unprognostic (1.70e-1)" "unprognostic (8.60e-3)" "unprognostic (3.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 2329.5;Hofbauer cells: 3371.1;Kupffer cells: 3606.6;Langerhans cells: 6658.3;Macrophages: 2836.0;monocytes: 4807.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 2132.7" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 90.2;Early spermatids: 67.9;Late spermatids: 201.9;Syncytiotrophoblasts: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.0" "Group enriched" "Detected in many" 8 "granulocytes: 45.0;T-cells: 12.4" "Cancer enhanced" "Detected in all" "lymphoma: 24.2" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.7;brain: 353.6" "Group enriched" "Detected in many" 4 "Astrocytes: 240.7;Oligodendrocyte precursor cells: 854.9;Oligodendrocytes: 484.8" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favorable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Cell type enriched" "Detected in many" 4 "Schwann cells: 720.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 17.4" "Colon - Enteric glia cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 11.2;Alveolar cells type 2: 8.8;Cholangiocytes: 9.6;Collecting duct cells: 13.8;Ductal cells: 6.7;granulocytes: 6.3;Muller glia cells: 15.5" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Kidney cancer: 25.0" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Sebaceous gland cells, Testis - Sertoli cells" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 41: Alveolar cells - Lung function" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 304.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 166.4;Cone photoreceptor cells: 579.0;Horizontal cells: 571.0;Oligodendrocytes: 154.4;Rod photoreceptor cells: 324.2" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 11.1" "Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 667.9;Ductal cells: 640.1;Fibroblasts: 830.3;Hepatocytes: 2202.4;Leydig cells: 755.1;Thymic epithelial cells: 1994.0" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Cancer enhanced" "Detected in many" "liver cancer: 32.4;testis cancer: 41.8" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 343.9;Inhibitory neurons: 536.3;Oligodendrocyte precursor cells: 163.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 7 "Fibroblasts: 712.4" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.9;Brain cancer: 15.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 354.3;Cardiomyocytes: 142.1;Excitatory neurons: 190.3;Inhibitory neurons: 157.2;Microglial cells: 121.3;Oligodendrocyte precursor cells: 399.5;Oligodendrocytes: 185.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 10.9" "Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 50: Enterocytes - Absorption" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" SHC3 "N-Shc, NSHC, SHCC" ENSG00000148082 "SHC adaptor protein 3" Q92529 9 89005771-89178818 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 152.9;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 319.6" "Cancer enriched" "Detected in some" 5 "glioma: 5.1" "Group enriched" "Detected in many" 9 "amygdala: 16.8;basal ganglia: 24.9;cerebral cortex: 28.1;hippocampal formation: 23.6;white matter: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.9;Sarcoma: 5.8" "Breast - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031427, HPA046656, HPA072448" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 27: TE 441.T - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "HPA031427: AB_2673877, HPA046656: AB_2679740, HPA072448: AB_2686521" "unprognostic (6.22e-2)" "unprognostic (5.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-4)" "unprognostic (2.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (2.72e-3)" "unprognostic (7.39e-2)" "unprognostic (1.53e-7)" "unprognostic (8.33e-2)" "unprognostic (1.05e-1)" "unprognostic (9.01e-2)" "unprognostic (9.84e-4)" SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Hepatocytes: 53.2;Inhibitory neurons: 21.1;Oligodendrocyte precursor cells: 22.1;Peritubular cells: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 57.1;Extravillous trophoblasts: 39.4;Proximal tubular cells: 156.1" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 33.2" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 186.9;Cone photoreceptor cells: 81.0;Rod photoreceptor cells: 70.1" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Group enriched" "Detected in some" 5 "Brain cancer: 4.9;breast cancer: 9.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 35: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 138.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 253.9;Inhibitory neurons: 534.8;Oligodendrocytes: 149.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 25.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 37: Neurons - Neuronal signaling" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 199.3;Fibroblasts: 112.0;Smooth muscle cells: 101.1;Thymic epithelial cells: 48.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.6;Distal enterocytes: 151.2;Proximal enterocytes: 339.5;Proximal tubular cells: 107.9;Syncytiotrophoblasts: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cancer enhanced" "Detected in all" "prostate cancer: 42.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 50: Enterocytes - Absorption" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" SMTNL2 FLJ42461 ENSG00000188176 "Smoothelin like 2" Q2TAL5 17 4583999-4608319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 500.8;tongue: 136.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 15.8;Distal tubular cells: 28.0;Proximal tubular cells: 36.9;Skeletal myocytes: 79.2;Thymic epithelial cells: 30.7" "Cancer enhanced" "Detected in many" "renal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 10.1" "Adipose visceral - Mesothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025706 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 6: BEWO - Unknown function" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA025706: AB_1848935" "unprognostic (8.62e-2)" "unprognostic (5.40e-2)" "unprognostic (7.13e-2)" "unprognostic (2.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.87e-2)" "unprognostic (4.89e-3)" "unprognostic (2.73e-1)" "unprognostic (3.73e-3)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (5.89e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-3)" "unprognostic (2.22e-1)" SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.6;Leydig cells: 404.2;Peritubular cells: 342.9;Schwann cells: 270.2;Smooth muscle cells: 423.5;Syncytiotrophoblasts: 227.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 103.8;Bipolar cells: 69.8;Excitatory neurons: 40.8;Muller glia cells: 33.0;Oligodendrocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 63: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 690.5;Endometrial stromal cells: 1211.8;Endothelial cells: 711.5;Fibroblasts: 1071.9;Peritubular cells: 1109.1;Schwann cells: 921.2;Sertoli cells: 1409.7;Smooth muscle cells: 1089.7;Theca cells: 924.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cancer enhanced" "Detected in all" "Brain cancer: 2554.7;skin cancer: 2512.0" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" SPSB4 SSB-4 ENSG00000175093 "SplA/ryanodine receptor domain and SOCS box containing 4" Q96A44 3 141051347-141148611 "Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.9;pancreas: 7.0;pituitary gland: 3.0;testis: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.0;Horizontal cells: 7.0;Late spermatids: 17.6;Oligodendrocyte precursor cells: 40.0;Spermatocytes: 18.3" "Group enriched" "Detected in some" 5 "glioma: 4.6;testis cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 7.7;Sarcoma: 4.8;testis cancer: 2.0" "Liver - Kupffer cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062793 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA062793: AB_2732689" "unprognostic (5.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.72e-4)" "unprognostic (7.49e-2)" "unprognostic (6.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-3)" "unprognostic (2.30e-2)" "unprognostic (2.46e-4)" "unprognostic (9.80e-3)" SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 70.2;Fibroblasts: 246.3;Granulosa cells: 146.3;Leydig cells: 106.3;Melanocytes: 76.6;Peritubular cells: 100.2;Smooth muscle cells: 96.6" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cancer enhanced" "Detected in many" "skin cancer: 195.4" "Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81413021-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 273.0;Excitatory neurons: 259.2;Inhibitory neurons: 341.4;Microglial cells: 330.2;Oligodendrocytes: 321.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "CAB020834: , HPA068605: AB_2732116, HPA071780: " "unprognostic (4.62e-2)" "unprognostic (1.96e-3)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.78e-3)" "unprognostic (2.36e-3)" "unprognostic (6.01e-2)" "unprognostic (1.01e-2)" "unprognostic (3.04e-3)" "unprognostic (6.56e-2)" "unprognostic (9.81e-2)" "unprognostic (4.39e-3)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.8;Fibroblasts: 26.6;Leydig cells: 18.6;Peritubular cells: 15.4;Schwann cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 11.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Fibroblasts: 138.9;Leydig cells: 188.9;Peritubular cells: 269.9;Skeletal myocytes: 172.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 65: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.3;Cone photoreceptor cells: 187.8;Excitatory neurons: 239.8;Horizontal cells: 123.0;Inhibitory neurons: 153.7;Rod photoreceptor cells: 182.5" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 38: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 87.0;Excitatory neurons: 62.5;Horizontal cells: 166.0;Inhibitory neurons: 104.7" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 9: Neurons - Nervous system development" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 533.0;Bipolar cells: 352.9;Excitatory neurons: 487.8;Inhibitory neurons: 471.5;Microglial cells: 307.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 111.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Bone cancer: 4.0" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 77: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 67.3;choroid plexus: 35.5;pituitary gland: 62.2;retina: 23.5;testis: 60.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.5;Muller glia cells: 62.4;Peritubular cells: 35.3;Sertoli cells: 210.1" "Cancer enhanced" "Detected in many" "glioma: 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 22.7" "Heart muscle - Fibroblasts, Pancreas - Alpha cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 35: Bipolar cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (1.30e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (9.68e-2)" "unprognostic (8.75e-4)" "unprognostic (1.21e-1)" "unprognostic (8.11e-2)" "prognostic favorable (8.60e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.74e-1)" "unprognostic (6.30e-2)" "unprognostic (6.03e-4)" TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 312.8;Microglial cells: 428.7;Oligodendrocyte precursor cells: 592.1;Oligodendrocytes: 1428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" TCF21 "bHLHa23, POD1" ENSG00000118526 "Transcription factor 21" O43680 6 133889113-133895553 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 100.4;ovary: 88.3;placenta: 137.2" "Group enriched" "Detected in some" 7 "Fibroblasts: 97.3;Leydig cells: 102.5;Peritubular cells: 116.9;Sertoli cells: 49.8;Smooth muscle cells: 58.2;Theca cells: 31.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.7;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Bone cancer: 11.3;liver cancer: 12.1;Rhabdoid: 38.0" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013189, HPA025769" Uncertain Supported Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "HPA013189: AB_10601215, HPA025769: " "unprognostic (2.43e-2)" "unprognostic (8.45e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "unprognostic (4.78e-5)" "unprognostic (2.58e-2)" "unprognostic (6.66e-2)" "unprognostic (9.74e-2)" "unprognostic (2.88e-2)" "unprognostic (2.91e-3)" "unprognostic (2.01e-2)" "unprognostic (8.48e-2)" "unprognostic (5.37e-2)" "unprognostic (2.95e-1)" TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 46.4;Alveolar cells type 2: 56.7;Astrocytes: 74.0;Leydig cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 145.8;Bipolar cells: 162.8;Horizontal cells: 99.3;Inhibitory neurons: 480.4;Microglial cells: 103.1;Oligodendrocyte precursor cells: 251.3" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 10.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 37: Neurons - Neuronal signaling" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 445.3;Late spermatids: 482.9;Leydig cells: 362.3;Melanocytes: 360.5;Peritubular cells: 748.7;Theca cells: 461.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 12: Non-specific - Chromatin organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 611.3;Late spermatids: 1387.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in many" "Adipocytes: 50.4;Basal prostatic cells: 47.9;Endothelial cells: 50.3;Fibroblasts: 31.8;Leydig cells: 38.9;Peritubular cells: 56.0" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "ovarian cancer: 68.2;Rhabdoid: 19.1" "Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Endometrial stromal cells: 17.6;Enteroendocrine cells: 16.3;Granulosa cells: 50.1" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 484.4;Club cells: 528.6;Early spermatids: 253.0;Ionocytes: 620.0;Suprabasal keratinocytes: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 59: Fibroblasts - Metabolism" "Cluster 5: Bronchus - Unknown function" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 14.1;Langerhans cells: 10.9;Smooth muscle cells: 12.4;Spermatocytes: 22.4;Thymic epithelial cells: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.1" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 15: Smooth muscle cells - Muscle contraction" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.1;Excitatory neurons: 100.4;Inhibitory neurons: 104.7;Spermatocytes: 99.2" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 52: Endometrial stromal cells - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;pancreas: 10.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 213.3;Inhibitory neurons: 285.3;Late spermatids: 67.4" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Group enriched" "Detected in many" 5 "basal ganglia: 4.9;cerebellum: 4.4;cerebral cortex: 2.5;hippocampal formation: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 7300000 "Cluster 22: Non-specific - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 37: Neurons - Neuronal signaling" "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 876.8;Excitatory neurons: 384.1;Inhibitory neurons: 182.7;Muller glia cells: 158.4;Oligodendrocyte precursor cells: 101.1" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 7.2;Rhabdoid: 11.8;skin cancer: 4.4" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 47: Retina - Visual perception" "Cluster 38: Neurons - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 199.2;Hofbauer cells: 221.7;Leydig cells: 176.1;Melanocytes: 170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 97.6;Fibroblasts: 68.1;granulocytes: 44.2;Langerhans cells: 30.1;Leydig cells: 46.8;Peritubular cells: 40.6;Thymic epithelial cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cancer enhanced" "Detected in many" "Sarcoma: 11.5" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 57: Non-specific - Translation" "Cluster 65: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 503.4;Endothelial cells: 357.5;Melanocytes: 329.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 969.7;Granulosa cells: 1101.8;Kupffer cells: 1041.7;Macrophages: 573.9;Oligodendrocyte precursor cells: 1575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 172.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 6173.1;Langerhans cells: 5043.7;Leydig cells: 5059.5;Muller glia cells: 8289.1;Schwann cells: 8855.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 28.2;Fibroblasts: 84.2;Granulosa cells: 44.9;Leydig cells: 118.7;Peritubular cells: 23.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cancer enriched" "Detected in many" 6 "testis cancer: 62.2" "Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 61.0;Granulosa cells: 96.1;Late spermatids: 153.1;Theca cells: 40.0" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.6" "Breast - Adipocytes (Breast), Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 526.4;monocytes: 928.0;NK-cells: 516.9;Oligodendrocytes: 1406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.5" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" ZFP1 "FLJ34243, ZNF475" ENSG00000184517 "ZFP1 zinc finger protein" Q6P2D0 16 75148494-75172236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044916, HPA062910" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Nucleoplasm "HPA044916: AB_2679144, HPA062910: AB_2684902" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.24e-5)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.99e-1)" "unprognostic (1.50e-1)" "unprognostic (4.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (9.80e-4)" "unprognostic (5.55e-1)" "unprognostic (6.64e-2)" "unprognostic (2.08e-1)" ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;skeletal muscle: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 73.1;Late spermatids: 113.2;Leydig cells: 27.9;Microglial cells: 52.0;Oligodendrocyte precursor cells: 37.1;Peritubular cells: 50.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.7;testis cancer: 17.6" "Colon - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-3)" "unprognostic (3.37e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.77e-1)" "unprognostic (9.13e-2)" "unprognostic (8.97e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.92e-2)" "unprognostic (5.84e-2)"