Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ADCY4	AC4	ENSG00000129467	"Adenylate cyclase 4"	Q8NFM4	14	24318349-24335093	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	6	"Adipocytes: 83.5;Endothelial cells: 74.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	9	"basophil: 2.9"	"Lineage enriched"	"Detected in single"	9	"granulocytes: 2.9"	"Not detected"	"Not detected"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB005070, HPA048344"	Approved					NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 66: Endothelial cells - Angiogenesis"			"CAB005070: AB_2273639, HPA048344: AB_2680366"	"unprognostic (5.59e-2)"	"unprognostic (1.34e-1)"	"unprognostic (3.47e-4)"	"prognostic favorable (8.20e-4)"	"unprognostic (4.06e-1)"	"unprognostic (2.82e-3)"	"unprognostic (1.75e-4)"	"unprognostic (8.58e-2)"	"unprognostic (2.51e-2)"	"unprognostic (7.88e-2)"	"unprognostic (6.77e-2)"	"unprognostic (7.87e-2)"	"prognostic unfavorable (7.01e-4)"	"unprognostic (8.02e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"
DIPK2B	"CXorf36, DIA1R, FLJ14103"	ENSG00000147113	"Divergent protein kinase domain 2B"	Q9H7Y0	X	45148373-45200901	"Disease related genes, Predicted secreted proteins"			"Autism, Autism spectrum disorder"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"Adipocytes: 173.4;Endothelial cells: 135.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA002806	Uncertain				"Secreted - unknown location"	NA	NA		940000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"			"HPA002806: AB_1078595"	"unprognostic (2.12e-1)"	"unprognostic (1.32e-2)"	"unprognostic (8.51e-3)"	"unprognostic (2.05e-1)"	"unprognostic (4.65e-2)"	"unprognostic (4.07e-3)"	"unprognostic (7.30e-2)"	"unprognostic (1.61e-1)"	"unprognostic (1.50e-1)"	"unprognostic (3.39e-1)"	"unprognostic (6.06e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.75e-3)"	"unprognostic (3.79e-3)"	"unprognostic (1.98e-1)"	"unprognostic (8.47e-2)"	"unprognostic (3.11e-2)"
ESAM	W117m	ENSG00000149564	"Endothelial cell adhesion molecule"	Q96AP7	11	124752583-124762290	"Plasma proteins, Predicted membrane proteins"	"Cell adhesion"			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 385.2;Endothelial cells: 271.5;Sertoli cells: 63.6;Smooth muscle cells: 101.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 8.2;naive B-cell: 7.5"	"Group enriched"	"Detected in many"	9	"B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2"	"Cancer enhanced"	"Detected in many"		"Leukemia: 15.7"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA056293, HPA072563"	Uncertain		Approved	"Cell Junctions,Cytosol"		NA	NA		82000000	"Cluster 34: Basophils - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 66: Endothelial cells - Angiogenesis"	"Cell Junctions"	Cytosol	"HPA056293: AB_2683089, HPA072563: "	"unprognostic (1.52e-1)"	"unprognostic (2.03e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.56e-1)"	"unprognostic (1.41e-2)"	"unprognostic (4.49e-3)"	"unprognostic (2.61e-1)"	"unprognostic (1.10e-1)"	"unprognostic (9.05e-2)"	"unprognostic (2.99e-2)"	"unprognostic (3.08e-1)"	"unprognostic (3.60e-1)"	"unprognostic (1.54e-1)"	"unprognostic (1.24e-2)"	"unprognostic (5.10e-2)"	"unprognostic (2.29e-1)"	"unprognostic (5.06e-2)"
GIMAP8	"DKFZp667I133, hIAN6, IAN9"	ENSG00000171115	"GTPase, IMAP family member 8"	Q8ND71	7	150450630-150479393	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 40.6"	"Group enriched"	"Detected in many"	4	"Adipocytes: 65.2;Endothelial cells: 82.1;Kupffer cells: 66.5;Macrophages: 30.7;Microglial cells: 31.9;monocytes: 35.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in some"	6	"Leukemia: 1.5;lymphoma: 2.3;Myeloma: 1.2"	"Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA014474, HPA017765"	Supported					NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"			"HPA014474: AB_1849685, HPA017765: AB_1849683"	"unprognostic (7.86e-2)"	"unprognostic (7.87e-3)"	"unprognostic (1.04e-1)"	"unprognostic (4.42e-3)"	"unprognostic (2.11e-1)"	"unprognostic (8.09e-3)"	"unprognostic (1.07e-3)"	"unprognostic (1.32e-2)"	"unprognostic (1.58e-1)"	"unprognostic (8.07e-2)"	"unprognostic (6.26e-3)"	"unprognostic (2.15e-1)"	"unprognostic (1.04e-3)"	"unprognostic (2.01e-1)"	"prognostic unfavorable (8.47e-4)"	"unprognostic (3.85e-1)"	"unprognostic (1.31e-1)"
ITGA5	"CD49e, FNRA"	ENSG00000161638	"Integrin subunit alpha 5"	P08648	12	54395261-54419266	"Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins"	"Cell adhesion, Host-virus interaction"	"Host cell receptor for virus entry, Integrin, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5"	"Cell type enriched"	"Detected in many"	4	"Extravillous trophoblasts: 447.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 89.1"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells"	"Region enriched"	"Detected in many"	5	"basal ganglia: 10.4"	"Low region specificity"	"Detected in many"			"HPA002642, CAB009008"	Enhanced					NA	NA		26000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 54: Extravillous trophoblasts - Unknown function"			"CAB009008: AB_647474, HPA002642: AB_1078469"	"unprognostic (7.51e-3)"	"prognostic unfavorable (4.07e-6)"	"prognostic unfavorable (8.43e-4)"	"unprognostic (1.58e-1)"	"unprognostic (8.51e-3)"	"prognostic unfavorable (2.91e-4)"	"prognostic unfavorable (2.23e-5)"	"prognostic unfavorable (2.44e-4)"	"unprognostic (2.76e-2)"	"unprognostic (6.19e-2)"	"unprognostic (8.99e-2)"	"unprognostic (8.28e-2)"	"prognostic unfavorable (1.32e-8)"	"unprognostic (2.11e-3)"	"unprognostic (3.35e-2)"	"prognostic unfavorable (8.89e-4)"	"unprognostic (2.18e-3)"
MCF2L	"ARHGEF14, DBS, KIAA0362, OST"	ENSG00000126217	"MCF.2 cell line derived transforming sequence like"	O15068	13	112894378-113099742	"Predicted intracellular proteins"		"Guanine-nucleotide releasing factor"	Proto-oncogene	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 134.5"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 127.9;Bipolar cells: 62.9;Cone photoreceptor cells: 98.2;Endothelial cells: 66.6;Intestinal goblet cells: 66.0;Microglial cells: 90.3;Oligodendrocytes: 70.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"skin cancer: 33.2"	"Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 66: Endothelial cells - Angiogenesis"				"unprognostic (1.56e-1)"	"unprognostic (2.53e-2)"	"unprognostic (8.86e-3)"	"prognostic favorable (6.01e-4)"	"unprognostic (9.07e-2)"	"unprognostic (3.91e-2)"	"unprognostic (7.07e-2)"	"unprognostic (3.02e-2)"	"unprognostic (1.94e-1)"	"unprognostic (2.11e-1)"	"prognostic favorable (4.36e-5)"	"unprognostic (1.17e-1)"	"prognostic favorable (9.14e-6)"	"unprognostic (2.04e-2)"	"unprognostic (1.28e-1)"	"unprognostic (2.24e-1)"	"prognostic favorable (2.63e-5)"
MMRN2	"EMILIN3, EndoGlyx-1, FLJ13465"	ENSG00000173269	"Multimerin 2"	Q9H8L6	10	86935540-86969481	"Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	Angiogenesis			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	7	"Adipocytes: 220.5;Endothelial cells: 134.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA020741			Approved	Vesicles	"Secreted to extracellular matrix"	NA	NA		84000000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	Vesicles		"HPA020741: AB_1848154"	"unprognostic (4.17e-1)"	"unprognostic (7.87e-2)"	"unprognostic (6.67e-3)"	"unprognostic (3.30e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.08e-2)"	"unprognostic (1.75e-3)"	"unprognostic (1.43e-1)"	"unprognostic (2.09e-2)"	"unprognostic (3.11e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.34e-1)"	"unprognostic (6.17e-3)"	"unprognostic (1.54e-3)"	"unprognostic (1.25e-1)"	"unprognostic (6.44e-2)"	"unprognostic (1.66e-1)"
NPR1	"ANPa, ANPRA, GUCY2A, NPRA"	ENSG00000169418	"Natriuretic peptide receptor 1"	P16066	1	153678688-153693992	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters"	"cGMP biosynthesis"	"Lyase, Receptor, Vasoactive"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 67.1"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 92.4;Alveolar cells type 2: 24.5;Endothelial cells: 55.0;Fibroblasts: 35.0"	"Group enriched"	"Detected in all"	4	"ovarian cancer: 39.2;renal cancer: 12.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"cervical cancer: 9.2;ovarian cancer: 8.1"	"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells"	"Region enriched"	"Detected in all"	5	"olfactory bulb: 18.7"	"Low region specificity"	"Detected in many"			HPA031087			Approved	"Nucleoplasm,Nucleoli,Plasma membrane"		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 66: Endothelial cells - Angiogenesis"	Nucleoli	"Nucleoplasm, Plasma membrane"	"HPA031087: AB_10601975"	"unprognostic (2.54e-1)"	"unprognostic (3.03e-3)"	"unprognostic (6.31e-2)"	"prognostic unfavorable (3.97e-4)"	"unprognostic (1.55e-1)"	"unprognostic (6.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.03e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.27e-2)"	"prognostic favorable (2.49e-4)"	"unprognostic (1.27e-1)"	"unprognostic (6.69e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.06e-1)"	"unprognostic (1.74e-2)"
PECAM1	CD31	ENSG00000261371	"Platelet and endothelial cell adhesion molecule 1"	P16284	17	64319415-64413776	"Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion, Phagocytosis"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"placenta: 455.1"	"Group enriched"	"Detected in many"	4	"Adipocytes: 691.0;Endothelial cells: 633.9;monocytes: 238.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"non-classical monocyte: 702.3"	"Low lineage specificity"	"Detected in all"			"Cancer enriched"	"Detected in many"	4	"Leukemia: 40.8"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004690, HPA004871"	Enhanced		Approved	"Nucleoli,Plasma membrane"		NA	NA		110000000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Plasma membrane"	Nucleoli	"HPA004690: AB_1078462, HPA004871: "	"unprognostic (2.79e-1)"	"unprognostic (2.14e-1)"	"unprognostic (2.79e-2)"	"unprognostic (2.76e-1)"	"unprognostic (1.34e-1)"	"unprognostic (4.42e-3)"	"unprognostic (2.84e-1)"	"unprognostic (2.37e-1)"	"unprognostic (2.57e-1)"	"unprognostic (7.25e-2)"	"unprognostic (4.53e-2)"	"unprognostic (9.68e-2)"	"prognostic unfavorable (8.98e-5)"	"unprognostic (9.72e-3)"	"unprognostic (9.57e-2)"	"unprognostic (1.56e-1)"	"unprognostic (4.16e-2)"
S1PR1	"CD363, D1S3362, edg-1, EDG1"	ENSG00000170989	"Sphingosine-1-phosphate receptor 1"	P21453	1	101236865-101243713	"Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters"	"Angiogenesis, Chemotaxis"	"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 261.4;Endothelial cells: 153.5;NK-cells: 58.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 1248.4"	"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"lymphoma: 21.9"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010104, HPA075568"	Supported		Supported	Vesicles		No	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	Vesicles		"CAB010104: AB_2238920, HPA075568: AB_2686758"	"unprognostic (1.41e-1)"	"unprognostic (9.35e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.61e-1)"	"unprognostic (9.78e-2)"	"unprognostic (4.49e-3)"	"unprognostic (1.34e-3)"	"unprognostic (1.99e-1)"	"unprognostic (1.36e-1)"	"unprognostic (9.12e-2)"	"unprognostic (2.34e-2)"	"unprognostic (2.23e-1)"	"unprognostic (5.82e-3)"	"unprognostic (2.54e-2)"	"unprognostic (1.04e-1)"	"unprognostic (3.64e-1)"	"prognostic unfavorable (8.78e-4)"
TIE1	"JTK14, TIE"	ENSG00000066056	"Tyrosine kinase with immunoglobulin like and EGF like domains 1"	P35590	1	43300982-43323108	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Angiogenesis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"Adipocytes: 126.1;Endothelial cells: 108.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	24	"basophil: 2.1;NK-cell: 2.5"	"Group enriched"	"Detected in many"	24	"granulocytes: 2.1;NK-cells: 2.5"	"Group enriched"	"Detected in many"	5	"Leukemia: 12.2;ovarian cancer: 22.4;Sarcoma: 24.1;thyroid cancer: 28.1"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"								"Intracellular and membrane"	NA	NA		87000000	"Cluster 41: Basophils - Cellular respiration"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"				"unprognostic (1.88e-1)"	"unprognostic (1.26e-1)"	"unprognostic (7.60e-3)"	"unprognostic (1.01e-1)"	"unprognostic (3.91e-2)"	"unprognostic (1.53e-3)"	"unprognostic (1.19e-2)"	"unprognostic (7.83e-2)"	"unprognostic (2.02e-1)"	"unprognostic (9.34e-2)"	"unprognostic (1.91e-2)"	"unprognostic (2.25e-1)"	"unprognostic (1.17e-3)"	"unprognostic (2.16e-2)"	"unprognostic (1.89e-1)"	"unprognostic (1.29e-2)"	"unprognostic (2.35e-2)"
VWF	F8VWF	ENSG00000110799	"Von Willebrand factor"	P04275	12	5948877-6124770	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins"	"Blood coagulation, Cell adhesion, Hemostasis"		"Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	11	"Adipocytes: 930.0;Endothelial cells: 826.7"	"Cancer enhanced"	"Detected in all"		"renal cancer: 76.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in some"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001694, HPA001815, HPA002082, CAB072874, CAB072875"	Supported				"Secreted to blood"	NA	NA	28300000000	5600000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"			"CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575"	"unprognostic (3.66e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.27e-1)"	"unprognostic (1.43e-1)"	"unprognostic (2.91e-3)"	"unprognostic (7.09e-2)"	"unprognostic (4.63e-1)"	"unprognostic (5.63e-2)"	"unprognostic (3.92e-2)"	"unprognostic (4.69e-1)"	"unprognostic (1.12e-1)"	"unprognostic (2.98e-2)"	"prognostic unfavorable (2.31e-4)"	"unprognostic (1.55e-1)"	"unprognostic (3.12e-1)"	"unprognostic (2.73e-3)"