Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
AIF1	"AIF-1, Em:AF129756.17, IBA1, IRT-1"	ENSG00000204472	"Allograft inflammatory factor 1"	P55008	6	31615217-31617021	"Predicted intracellular proteins"		Actin-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 235.0;lymphoid tissue: 346.6"	"Group enriched"	"Detected in many"	7	"Hofbauer cells: 2459.1;Kupffer cells: 1902.8;Langerhans cells: 1685.0;Macrophages: 1457.6;monocytes: 3085.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	26	"classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5"	"Group enriched"	"Detected in all"	74	"dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5"	"Cancer enriched"	"Detected in some"	28	"Leukemia: 77.4"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049234, HPA062949"	Enhanced		Uncertain	Cytosol		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 2: Immune cells - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	Cytosol		"HPA049234: AB_2680685, HPA062949: AB_2732694"	"unprognostic (3.20e-2)"	"unprognostic (7.21e-3)"	"unprognostic (6.11e-2)"	"unprognostic (2.33e-2)"	"unprognostic (2.46e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.98e-2)"	"unprognostic (4.83e-2)"	"unprognostic (2.72e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.94e-1)"	"prognostic unfavorable (2.30e-5)"	"unprognostic (1.29e-1)"	"unprognostic (1.02e-2)"	"unprognostic (9.59e-2)"	"unprognostic (4.89e-2)"
CSF1R	"C-FMS, CD115, CSFR, FMS"	ENSG00000182578	"Colony stimulating factor 1 receptor"	P07333	5	150053291-150113372	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Immunity, Inflammatory response, Innate immunity"	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 113.3;placenta: 103.3"	"Group enriched"	"Detected in many"	5	"Extravillous trophoblasts: 116.5;Hofbauer cells: 330.9;Kupffer cells: 139.9;Langerhans cells: 99.2;Macrophages: 223.6;Microglial cells: 131.3;monocytes: 181.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"intermediate monocyte: 444.6;non-classical monocyte: 646.9"	"Lineage enriched"	"Detected in many"	5	"monocytes: 646.9"	"Cancer enhanced"	"Detected in many"		"Leukemia: 10.7"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008970, HPA012323"	Approved		Supported	"Vesicles,Plasma membrane"	"Intracellular and membrane"	NA	NA		1600000000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 69: Macrophages - Innate immune response"	"Vesicles, Plasma membrane"		"CAB008970: , HPA012323: AB_1848977"	"unprognostic (3.82e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.86e-3)"	"unprognostic (9.83e-2)"	"unprognostic (1.20e-1)"	"unprognostic (7.33e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.45e-1)"	"unprognostic (9.37e-2)"	"unprognostic (1.11e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.65e-1)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (3.67e-2)"	"prognostic unfavorable (4.92e-4)"	"unprognostic (1.72e-2)"	"unprognostic (4.61e-2)"
CYBB	"CGD, GP91-PHOX, NOX2"	ENSG00000165168	"Cytochrome b-245 beta chain"	P04839	X	37780059-37813461	"Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters"	"Electron transport, Ion transport, Transport"	"Ion channel, Oxidoreductase, Voltage-gated channel"	"Chronic granulomatous disease, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 160.9;lymphoid tissue: 158.9"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 334.1;Hofbauer cells: 226.4;Kupffer cells: 358.4;Macrophages: 451.2;monocytes: 516.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"classical monocyte: 276.3;intermediate monocyte: 261.6"	"Group enriched"	"Detected in many"	4	"dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3"	"Cancer enhanced"	"Detected in some"		"Leukemia: 17.9;lymphoma: 28.4"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA051227	Enhanced					NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"			"HPA051227: AB_2681395"	"unprognostic (5.83e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.15e-3)"	"unprognostic (1.48e-2)"	"unprognostic (1.27e-1)"	"unprognostic (5.65e-2)"	"unprognostic (2.29e-2)"	"unprognostic (4.45e-2)"	"unprognostic (9.14e-2)"	"unprognostic (2.32e-2)"	"unprognostic (5.73e-2)"	"unprognostic (5.18e-2)"	"unprognostic (5.92e-2)"	"unprognostic (3.02e-1)"	"unprognostic (2.48e-2)"	"unprognostic (1.32e-1)"	"unprognostic (9.72e-2)"
SPI1	"OF, PU.1, SFPI1, SPI-1, SPI-A"	ENSG00000066336	"Spi-1 proto-oncogene"	P17947	11	47354860-47378547	"Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, RNA-binding"	Proto-oncogene	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	6	"bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7"	"Group enriched"	"Detected in many"	4	"Hofbauer cells: 490.5;Kupffer cells: 283.2;Langerhans cells: 617.7;Macrophages: 432.6;monocytes: 546.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 179.7"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 179.7"	"Group enriched"	"Detected in some"	14	"Leukemia: 124.1;lymphoma: 61.4"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004079, HPA044653"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 19: Macrophages - Innate immune response"	Nucleoplasm		"CAB004079: AB_10692379, HPA044653: AB_2679036"	"unprognostic (4.45e-2)"	"unprognostic (3.31e-3)"	"unprognostic (2.92e-2)"	"unprognostic (1.66e-2)"	"unprognostic (5.97e-2)"	"unprognostic (3.33e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.35e-2)"	"unprognostic (2.79e-1)"	"unprognostic (3.36e-1)"	"unprognostic (1.78e-1)"	"prognostic unfavorable (2.07e-5)"	"unprognostic (1.20e-1)"	"unprognostic (4.95e-2)"	"unprognostic (2.40e-1)"	"unprognostic (4.92e-2)"
TYROBP	"DAP12, KARAP, PLO-SL, PLOSL"	ENSG00000011600	"Transmembrane immune signaling adaptor TYROBP"	O43914	19	35904401-35908295	"Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters"	Immunity			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 596.8;lymphoid tissue: 423.3"	"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 5212.6;Kupffer cells: 2893.4;Langerhans cells: 2460.5;Macrophages: 2602.8;monocytes: 3238.5;NK-cells: 1335.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 6415.4"	"Low lineage specificity"	"Detected in all"			"Cancer enriched"	"Detected in some"	53	"Leukemia: 105.6"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009493, HPA041899"	Enhanced		Supported	"Plasma membrane"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	"Plasma membrane"		"CAB009493: AB_638987, HPA041899: AB_10795266"	"unprognostic (7.09e-2)"	"unprognostic (8.38e-3)"	"unprognostic (7.87e-2)"	"unprognostic (4.76e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.39e-1)"	"unprognostic (5.27e-2)"	"unprognostic (8.04e-2)"	"unprognostic (2.07e-2)"	"unprognostic (2.47e-1)"	"unprognostic (2.91e-1)"	"unprognostic (1.50e-1)"	"prognostic unfavorable (1.05e-4)"	"unprognostic (4.47e-2)"	"unprognostic (1.72e-2)"	"unprognostic (4.27e-2)"	"unprognostic (4.39e-2)"