Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CACNA1D	"CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2"	ENSG00000157388	"Calcium voltage-gated channel subunit alpha1 D"	Q01668	3	53328963-53813733	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Calcium transport, Ion transport, Transport"	"Calcium channel, Ion channel, Voltage-gated channel"	"Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 10.4"	"Group enriched"	"Detected in many"	5	"Excitatory neurons: 247.6;Horizontal cells: 114.1;Inhibitory neurons: 345.8;Microglial cells: 123.1;Oligodendrocyte precursor cells: 189.2"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 5.9"	"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in single"	10	"basophil: 3.7"	"Lineage enriched"	"Detected in single"	21	"granulocytes: 3.7"	"Low cancer specificity"	"Detected in many"			"Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA020215	Uncertain		Approved	"Nuclear membrane"		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 68: Epididymis - Unknown function"	"Cluster 50: L-1236 & L-428 - Unknown function"	"Cluster 37: Neurons - Neuronal signaling"	"Nuclear membrane"		"HPA020215: AB_1845860"	"unprognostic (5.85e-2)"	"unprognostic (4.90e-3)"	"unprognostic (5.09e-2)"	"unprognostic (2.24e-2)"	"unprognostic (7.55e-2)"	"unprognostic (1.77e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.32e-2)"	"unprognostic (2.95e-1)"	"unprognostic (4.42e-2)"	"unprognostic (3.90e-3)"	"unprognostic (1.53e-1)"	"prognostic favorable (8.34e-8)"	"unprognostic (1.14e-1)"	"unprognostic (3.05e-2)"	"unprognostic (8.09e-3)"	"unprognostic (6.70e-3)"
NRIP2	DKFZP761G1913	ENSG00000053702	"Nuclear receptor interacting protein 2"	Q9BQI9	12	2825348-2835544	"Predicted intracellular proteins"	"Transcription, Transcription regulation"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 23.4"	"Cell type enhanced"	"Detected in some"		"Peritubular cells: 6.1;Rod photoreceptor cells: 10.5;Schwann cells: 6.2;Sertoli cells: 11.1;Smooth muscle cells: 19.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	4	"basophil: 3.7"	"Lineage enriched"	"Detected in single"	4	"granulocytes: 3.7"	"Low cancer specificity"	"Detected in all"			"Heart muscle - Smooth muscle cells, Testis - Peritubular cells, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039197, HPA039860"	Enhanced		Approved	"Nucleoplasm,Nuclear bodies,Cytosol"		Yes	No			"Cluster 34: Basophils - Unknown function"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 7: Neuronal cell lines - Stereocilium"	"Cluster 72: Smooth muscle cells - ECM organization"	"Nucleoplasm, Cytosol"	"Nuclear bodies"	"HPA039197: AB_10673416, HPA039860: AB_10794203"	"unprognostic (3.28e-3)"	"unprognostic (3.83e-1)"	"prognostic unfavorable (8.05e-4)"	"unprognostic (2.10e-2)"	"unprognostic (8.11e-2)"	"unprognostic (4.26e-3)"	"unprognostic (5.66e-2)"	"unprognostic (4.42e-3)"	"unprognostic (2.89e-1)"	"unprognostic (4.39e-2)"	"prognostic favorable (8.69e-5)"	"unprognostic (7.15e-2)"	"unprognostic (2.82e-2)"	"unprognostic (7.55e-2)"	"unprognostic (5.23e-2)"	"unprognostic (1.00e-1)"	"unprognostic (8.97e-2)"
PDE5A		ENSG00000138735	"Phosphodiesterase 5A"	O76074	4	119494397-119628804	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Hydrolase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 65.2;Inhibitory neurons: 56.9;Oligodendrocyte precursor cells: 54.4;Peritubular cells: 98.2;Smooth muscle cells: 74.7"	"Group enriched"	"Detected in all"	4	"prostate cancer: 7.0;thyroid cancer: 27.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Peritubular cells, Thyroid - Fibroblasts"	"Region enhanced"	"Detected in all"		"cerebellum: 18.2"	"Low region specificity"	"Detected in all"			"HPA004729, HPA012873"	Approved		Approved	Cytosol		NA	NA		850000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 15: Smooth muscle cells - Muscle contraction"	Cytosol		"HPA004729: AB_1079588, HPA012873: AB_1855124"	"unprognostic (6.95e-2)"	"prognostic favorable (5.20e-4)"	"unprognostic (1.28e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.66e-2)"	"unprognostic (7.36e-2)"	"unprognostic (2.58e-2)"	"unprognostic (2.29e-2)"	"unprognostic (6.97e-2)"	"unprognostic (2.05e-2)"	"unprognostic (2.54e-1)"	"unprognostic (2.16e-2)"	"unprognostic (1.52e-2)"	"unprognostic (8.98e-2)"	"unprognostic (8.71e-3)"	"prognostic unfavorable (1.17e-4)"
WNT2B	"WNT13, XWNT2"	ENSG00000134245	"Wnt family member 2B"	Q93097	1	112466541-112530165	"Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"	"Wnt signaling pathway"	"Developmental protein"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"Leydig cells: 83.3;Peritubular cells: 193.6"	"Cancer enhanced"	"Detected in many"		"testis cancer: 4.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose visceral - Mesothelial cells, Testis - Peritubular cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA047274, HPA066368"			Approved	Nucleoplasm,Vesicles	"Secreted to extracellular matrix"	NA	NA				"Cluster 46: Fibroblasts - ECM organization"	"Cluster 68: Kidney - Mixed function"	"Cluster 53: Connective tissue cells - ECM organization"	Vesicles	Nucleoplasm	"HPA047274: AB_2732539, HPA066368: AB_2685664"	"unprognostic (2.08e-3)"	"unprognostic (2.06e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.49e-1)"	"unprognostic (9.42e-2)"	"unprognostic (4.90e-3)"	"unprognostic (1.15e-1)"	"unprognostic (2.37e-1)"	"unprognostic (5.94e-2)"	"unprognostic (1.13e-1)"	"unprognostic (5.65e-4)"	"unprognostic (5.41e-2)"	"unprognostic (7.64e-2)"	"unprognostic (4.80e-2)"	"unprognostic (2.49e-2)"
