Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
AQP9	"HsT17287, SSC1"	ENSG00000103569	"Aquaporin 9"	O43315	15	58138169-58185911	"Metabolic proteins, Predicted membrane proteins, Transporters"	Transport			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	10	"liver: 702.7"	"Cell type enhanced"	"Detected in some"		"Hepatocytes: 281.2;Hofbauer cells: 72.6;Kupffer cells: 88.6;Macrophages: 67.8;monocytes: 174.8"	"Cancer enriched"	"Detected in many"	30	"liver cancer: 132.4"	"Region enhanced"	"Detected in many"		"cerebral cortex: 14.4"	"Immune cell enriched"	"Detected in many"	20	"neutrophil: 1161.4"	"Lineage enriched"	"Detected in many"	20	"granulocytes: 1161.4"	"Cancer enriched"	"Detected in some"	7	"lymphoma: 10.1"	"Adipose subcutaneous - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"HPA074762, CAB075684"	Enhanced					NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 54: Lymphoma - Cytokine signaling"	"Cluster 33: Macrophages - Degranulation"			"CAB075684: , HPA074762: AB_2732267"	"unprognostic (1.91e-1)"	"unprognostic (1.92e-1)"	"unprognostic (7.30e-2)"	"unprognostic (2.67e-1)"	"unprognostic (1.24e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.36e-3)"	"unprognostic (2.28e-2)"	"unprognostic (3.82e-2)"	"unprognostic (2.03e-1)"	"unprognostic (4.80e-3)"	"unprognostic (6.98e-2)"	"prognostic unfavorable (5.72e-11)"	"unprognostic (8.78e-2)"	"unprognostic (1.13e-2)"	"unprognostic (1.25e-1)"	"unprognostic (8.39e-2)"
ARG1		ENSG00000118520	"Arginase 1"	P05089	6	131470832-131584332	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle"	Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"liver: 1203.5"	"Cell type enriched"	"Detected in some"	18	"Hepatocytes: 1111.5"	"Cancer enriched"	"Detected in some"	45	"liver cancer: 167.7"	"Low region specificity"	"Detected in single"			"Immune cell enriched"	"Detected in some"	5	"neutrophil: 44.9"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 44.9"	"Group enriched"	"Detected in some"	7	"Leukemia: 1.6;liver cancer: 1.8"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils"	"Region enhanced"	"Detected in single"		"cerebellum: 2.4"	"Low region specificity"	"Detected in all"			"HPA003595, CAB009434, HPA024006, CAB056159, CAB080011"	Enhanced					NA	NA		9500000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 13: Hepatocytes - Oxidoreductase activity"			"CAB009434: AB_2058955, CAB056159: AB_2665582, CAB080011: , HPA003595: AB_1078190, HPA024006: AB_1844987"	"unprognostic (2.00e-1)"	"unprognostic (2.09e-1)"	"unprognostic (2.49e-1)"	"unprognostic (1.74e-1)"	"unprognostic (9.95e-2)"	"unprognostic (7.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.56e-2)"	"unprognostic (7.55e-3)"	"unprognostic (8.35e-2)"	"unprognostic (1.25e-2)"	"unprognostic (2.90e-2)"	"unprognostic (2.75e-1)"	"unprognostic (1.11e-2)"	"unprognostic (1.79e-2)"
CD177	"HNA2A, NB1, PRV1"	ENSG00000204936	"CD177 molecule"		19	43353686-43363172	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"			"Tissue enhanced"	"Detected in many"		"bone marrow: 285.9;intestine: 164.6"	"Cell type enriched"	"Detected in some"	6	"Distal enterocytes: 308.7"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 27.6"	"Group enriched"	"Detected in many"	4	"cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3"	"Immune cell enriched"	"Detected in some"	7	"neutrophil: 8.7"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 8.7"	"Cancer enriched"	"Detected in many"	15	"Rhabdoid: 53.7"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA041820, HPA046601, HPA077640"	Enhanced				"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 22: Rhabdoid cancers - Neuronal signaling"	"Cluster 50: Enterocytes - Absorption"			"HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: "	"unprognostic (4.32e-2)"	"prognostic favorable (3.66e-4)"	"unprognostic (1.04e-2)"	"unprognostic (2.04e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.89e-2)"	"unprognostic (7.10e-2)"	"unprognostic (2.94e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.45e-1)"	"unprognostic (8.38e-2)"	"unprognostic (1.90e-2)"	"unprognostic (2.45e-1)"	"unprognostic (2.70e-1)"	"unprognostic (1.16e-1)"	"unprognostic (5.01e-2)"	"unprognostic (1.24e-1)"
CSF3R	"CD114, GCSFR"	ENSG00000119535	"Colony stimulating factor 3 receptor"	Q99062	1	36466043-36483278	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	Receptor	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1"	"Group enriched"	"Detected in many"	5	"Cytotrophoblasts: 399.6;Syncytiotrophoblasts: 1372.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"neutrophil: 1962.3"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 1962.3"	"Cancer enriched"	"Detected in some"	19	"Leukemia: 48.0"	"Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB017116, HPA048086"	Enhanced				"Intracellular and membrane"	NA	NA		150000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 67: Syncytiotrophoblasts - Pregnancy"			"CAB017116: , HPA048086: AB_2680257"	"unprognostic (5.57e-3)"	"unprognostic (8.05e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.87e-2)"	"unprognostic (2.88e-1)"	"unprognostic (2.92e-2)"	"unprognostic (2.86e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.83e-1)"	"unprognostic (5.65e-2)"	"unprognostic (2.47e-1)"	"unprognostic (3.44e-1)"	"prognostic unfavorable (5.72e-4)"	"unprognostic (6.33e-2)"	"prognostic unfavorable (3.79e-4)"	"unprognostic (2.03e-1)"	"unprognostic (2.31e-2)"
CXCR1	"CD181, CDw128a, CKR-1, CMKAR1, IL8RA"	ENSG00000163464	"C-X-C motif chemokine receptor 1"	P25024	2	218162841-218166962	"Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins"	Chemotaxis	"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 40.5"	"Group enriched"	"Detected in some"	5	"NK-cells: 10.0;Serous glandular cells: 4.1"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in some"			"Immune cell enriched"	"Detected in many"	14	"neutrophil: 1472.7"	"Lineage enriched"	"Detected in many"	62	"granulocytes: 1472.7"	"Not detected"	"Not detected"			"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"							HPA031991	Uncertain					NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 33: Macrophages - Degranulation"			"HPA031991: AB_2674103"	"unprognostic (2.80e-1)"	"unprognostic (2.91e-2)"	"unprognostic (3.53e-2)"	"unprognostic (5.74e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.68e-1)"	"unprognostic (2.14e-2)"	"unprognostic (3.36e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.57e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.15e-2)"	"unprognostic (2.88e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.97e-1)"	"unprognostic (1.30e-1)"	"unprognostic (8.85e-2)"
CXCR2	"CD182, CMKAR2, IL8RB"	ENSG00000180871	"C-X-C motif chemokine receptor 2"	P25025	2	218125289-218137251	"Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins"	Chemotaxis	"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 27.2;lymphoid tissue: 40.0"	"Cell type enhanced"	"Detected in some"		"NK-cells: 31.3;Serous glandular cells: 15.1;Squamous epithelial cells: 13.8;Suprabasal keratinocytes: 16.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Immune cell enriched"	"Detected in many"	52	"neutrophil: 3273.9"	"Lineage enriched"	"Detected in many"	111	"granulocytes: 3273.9"	"Cancer enriched"	"Detected in single"	6	"Leukemia: 5.6"	"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"					"Low region specificity"	"Detected in all"			"CAB016268, HPA031999, HPA032017"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle"		Yes	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	"Plasma membrane"	"Nucleoplasm, Microtubules, Mitotic spindle"	"CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112"	"unprognostic (4.89e-2)"	"unprognostic (2.01e-1)"	"unprognostic (5.63e-2)"	"unprognostic (1.10e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.13e-1)"	"unprognostic (1.33e-1)"	"unprognostic (2.13e-1)"	"unprognostic (5.96e-2)"	"unprognostic (1.22e-2)"	"unprognostic (5.67e-2)"	"unprognostic (1.41e-1)"	"unprognostic (7.54e-2)"	"unprognostic (1.04e-1)"	"unprognostic (7.23e-2)"	"unprognostic (8.18e-2)"	"unprognostic (5.48e-2)"
FCAR	CD89	ENSG00000186431	"Fc fragment of IgA receptor"	P24071	19	54874235-54891420	"CD markers, Predicted intracellular proteins, Predicted membrane proteins"		"IgA-binding protein, Receptor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5"	"Group enriched"	"Detected in some"	4	"Kupffer cells: 25.6;Macrophages: 17.5;monocytes: 25.1"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	8	"classical monocyte: 1.2;neutrophil: 4.0"	"Group enriched"	"Detected in many"	27	"granulocytes: 4.0;monocytes: 1.2"	"Not detected"	"Not detected"			"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"					"Not detected"	"Not detected"			HPA014050	Approved		Supported	"Plasma membrane"	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	"Plasma membrane"		"HPA014050: AB_1846338"	"unprognostic (1.46e-1)"	"unprognostic (5.74e-2)"	"unprognostic (1.30e-1)"	"unprognostic (4.71e-3)"	"unprognostic (3.46e-1)"	"unprognostic (2.02e-1)"	"unprognostic (7.99e-2)"	"unprognostic (1.54e-2)"	"unprognostic (1.59e-2)"	"unprognostic (4.70e-2)"	"unprognostic (1.41e-2)"	"unprognostic (7.05e-2)"	"unprognostic (4.19e-6)"	"unprognostic (9.23e-2)"	"unprognostic (8.10e-3)"	"unprognostic (8.04e-3)"	"unprognostic (9.81e-2)"
FCGR3B	"CD16, CD16b, FCG3, FCGR3"	ENSG00000162747	"Fc fragment of IgG receptor IIIb"	O75015	1	161623196-161631963	"CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"IgG-binding protein, Receptor"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 36.6;lymphoid tissue: 82.0"	"Cell type enriched"	"Detected in some"	5	"Serous glandular cells: 22.2"	"Low cancer specificity"	"Detected in many"			"Region enhanced"	"Detected in many"		"cerebral cortex: 6.7"	"Immune cell enriched"	"Detected in many"	79	"neutrophil: 7208.7"	"Lineage enriched"	"Detected in many"	79	"granulocytes: 7208.7"	"Not detected"	"Not detected"			"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"														"Secreted to blood"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 33: Macrophages - Degranulation"				"unprognostic (1.60e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.59e-3)"	"unprognostic (4.16e-2)"	"unprognostic (1.15e-1)"	"unprognostic (6.52e-2)"	"unprognostic (3.97e-2)"	"unprognostic (6.96e-3)"	"unprognostic (2.53e-2)"	"unprognostic (1.02e-1)"	"unprognostic (1.07e-1)"	"unprognostic (8.67e-2)"	"unprognostic (5.16e-2)"	"unprognostic (1.35e-1)"	"unprognostic (8.37e-3)"	"unprognostic (2.28e-1)"	"unprognostic (9.24e-2)"
MEFV	"FMF, MEF, TRIM20"	ENSG00000103313	"MEFV innate immuity regulator, pyrin"	O15553	16	3242027-3256633	"Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Immunity, Inflammatory response, Innate immunity"	Actin-binding	"Amyloidosis, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 6.1;lymphoid tissue: 8.9"	"Group enriched"	"Detected in some"	5	"Kupffer cells: 17.3;Macrophages: 14.5;monocytes: 46.8"	"Low cancer specificity"	"Detected in single"			"Low region specificity"	"Detected in single"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 8.3"	"Group enriched"	"Detected in many"	4	"granulocytes: 8.3;monocytes: 5.7"	"Cancer enhanced"	"Detected in single"		"Leukemia: 1.1"	"Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Breast - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Skin - Macrophages, Thyroid - Neutrophils"	"Not detected"	"Not detected"							HPA077497			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 2: Immune cells - Immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	Nucleoplasm	Cytosol	"HPA077497: "	"unprognostic (2.67e-1)"	"unprognostic (1.06e-1)"	"unprognostic (4.96e-2)"	"unprognostic (2.01e-1)"	"unprognostic (2.49e-2)"	"unprognostic (3.10e-1)"	"unprognostic (7.06e-2)"	"unprognostic (3.35e-2)"	"unprognostic (2.97e-2)"	"unprognostic (1.09e-1)"	"unprognostic (8.89e-2)"	"unprognostic (3.27e-1)"	"unprognostic (7.58e-7)"	"unprognostic (1.08e-1)"	"unprognostic (7.16e-4)"	"unprognostic (1.73e-3)"	"unprognostic (1.48e-1)"
MGAM	MGA	ENSG00000257335	Maltase-glucoamylase	O43451	7	141907813-142106747	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins"		"Glycosidase, Hydrolase, Multifunctional enzyme"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"epididymis: 25.5;intestine: 87.6"	"Group enriched"	"Detected in some"	7	"Late spermatids: 159.9;Proximal enterocytes: 509.8"	"Cancer enriched"	"Detected in some"	7	"renal cancer: 4.9"	"Region enhanced"	"Detected in single"		"cerebral cortex: 2.3"	"Immune cell enriched"	"Detected in some"	7	"neutrophil: 13.5"	"Lineage enriched"	"Detected in single"	102	"granulocytes: 13.5"	"Cancer enhanced"	"Detected in some"		"skin cancer: 5.3"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Region enriched"	"Detected in single"	12	"olfactory bulb: 2.0"	"Low region specificity"	"Detected in many"			HPA002270	Enhanced					NA	NA		310000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 33: Skin cancer - Membrane components"	"Cluster 59: Proximal enterocytes - Transmembrane transport"			"HPA002270: AB_1079366"	"unprognostic (1.02e-2)"	"unprognostic (1.45e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.95e-3)"	"unprognostic (2.80e-1)"	"unprognostic (7.81e-2)"	"unprognostic (7.32e-3)"	"unprognostic (3.83e-2)"	"unprognostic (4.97e-1)"	"unprognostic (2.17e-2)"	"unprognostic (6.86e-2)"	"unprognostic (1.99e-1)"	"prognostic favorable (6.16e-5)"	"unprognostic (1.82e-1)"	"unprognostic (2.82e-1)"	"unprognostic (1.34e-3)"	"unprognostic (3.03e-1)"
MMP8	CLG1	ENSG00000118113	"Matrix metallopeptidase 8"	P22894	11	102711796-102727050	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Collagen degradation"	"Hydrolase, Metalloprotease, Protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	36	"bone marrow: 501.1"	"Cell type enhanced"	"Detected in some"		"Hofbauer cells: 3.5;Macrophages: 1.3"	"Cancer enriched"	"Detected in single"	17	"melanoma: 5.7"	"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"non-classical monocyte: 1.7"	"Lineage enhanced"	"Detected in single"		"monocytes: 1.7"	"Cancer enriched"	"Detected in some"	40	"skin cancer: 51.6"	"Lung - Neutrophil_1, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA021221, HPA021763, HPA022935"	Enhanced		Approved	Vesicles	"Secreted to extracellular matrix"	NA	NA		360000	"Cluster 7: Monocytes - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 33: Skin cancer - Membrane components"	"Cluster 33: Macrophages - Degranulation"	Vesicles		"HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044"	"unprognostic (3.03e-1)"	"unprognostic (8.49e-5)"	"unprognostic (1.08e-2)"	"unprognostic (3.95e-3)"	"unprognostic (1.80e-1)"	"unprognostic (1.01e-2)"		"unprognostic (7.68e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.92e-2)"	"unprognostic (6.64e-3)"		"unprognostic (2.45e-6)"	"unprognostic (2.33e-4)"	"unprognostic (1.33e-1)"	"unprognostic (4.97e-1)"	"unprognostic (2.30e-2)"
PADI4	"PAD, PADI5, PDI4, PDI5"	ENSG00000159339	"Peptidyl arginine deiminase 4"	Q9UM07	1	17308195-17364004	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Immunity, Innate immunity, Transcription, Transcription regulation"	"Chromatin regulator, Hydrolase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	9	"bone marrow: 105.1;lymphoid tissue: 29.9"	"Cell type enhanced"	"Detected in some"		"dendritic cells: 14.8;granulocytes: 5.6;Hofbauer cells: 8.0;Kupffer cells: 5.3;Macrophages: 8.8;monocytes: 16.0;NK-cells: 8.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	8	"basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0"	"Group enriched"	"Detected in all"	9	"granulocytes: 183.0;monocytes: 71.3"	"Cancer enriched"	"Detected in single"	11	"Leukemia: 3.3"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Sebaceous gland cells, Stomach - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA017007, HPA042825"	Enhanced					NA	NA		29000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"			"HPA017007: AB_1854921, HPA042825: AB_2678189"	"unprognostic (1.70e-1)"	"unprognostic (2.25e-1)"	"unprognostic (2.23e-1)"	"unprognostic (2.98e-1)"	"unprognostic (1.27e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.47e-1)"	"unprognostic (4.91e-2)"	"unprognostic (8.49e-2)"	"unprognostic (5.22e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.66e-3)"	"unprognostic (1.50e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.56e-2)"	"unprognostic (1.80e-1)"
PGLYRP1	"PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L"	ENSG00000008438	"Peptidoglycan recognition protein 1"	O75594	19	46019153-46023053	"Metabolic proteins, Plasma proteins, Predicted secreted proteins"	"Immunity, Innate immunity"	"Antibiotic, Antimicrobial"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	15	"bone marrow: 629.4"	"Cell type enhanced"	"Detected in some"		"Excitatory neurons: 1.7;Inhibitory neurons: 1.4;Serous glandular cells: 1.2"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in some"		"cerebellum: 3.4"	"Group enriched"	"Detected in some"	202	"eosinophil: 443.7;neutrophil: 494.6"	"Lineage enriched"	"Detected in many"	213	"granulocytes: 494.6"	"Low cancer specificity"	"Detected in some"			"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA045702, HPA070227"	Enhanced		Approved	Nucleoplasm,Vesicles,Cytosol	"Secreted to blood"	NA	NA		35000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	Vesicles	"Nucleoplasm, Cytosol"	"HPA045702: AB_10960204, HPA070227: "	"unprognostic (2.87e-2)"	"unprognostic (4.26e-1)"	"unprognostic (1.32e-1)"	"unprognostic (3.04e-1)"	"unprognostic (1.58e-1)"	"unprognostic (4.93e-3)"	"unprognostic (2.20e-1)"	"unprognostic (6.46e-2)"	"unprognostic (7.77e-2)"	"unprognostic (2.61e-2)"	"unprognostic (8.51e-3)"	"unprognostic (7.18e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.73e-1)"	"unprognostic (4.37e-3)"
PROK2	"BV8, KAL4, MIT1, PK2"	ENSG00000163421	"Prokineticin 2"	Q9HC23	3	71771655-71785206	"Disease related genes, Human disease related genes, Predicted secreted proteins"	"Biological rhythms"	Neuropeptide	"Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 64.5;lymphoid tissue: 22.5"	"Cell type enhanced"	"Detected in some"		"Erythroid cells: 5.3;Hofbauer cells: 5.0;Kupffer cells: 10.0;Macrophages: 11.1;Serous glandular cells: 9.4;Spermatocytes: 18.4"	"Cancer enhanced"	"Detected in some"		"ovarian cancer: 2.1"	"Region enriched"	"Detected in many"	7	"cerebral cortex: 13.3"	"Immune cell enriched"	"Detected in many"	50	"neutrophil: 414.4"	"Lineage enriched"	"Detected in many"	50	"granulocytes: 414.4"	"Cancer enhanced"	"Detected in some"		"Leukemia: 8.0;Myeloma: 5.9"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Testis - Early spermatids, Thyroid - Neutrophils"	"Group enriched"	"Detected in some"	6	"basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5"	"Low region specificity"	"Detected in all"			HPA041408	Approved				"Secreted to blood"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"			"HPA041408: AB_10964057"	"unprognostic (5.24e-2)"	"unprognostic (3.13e-3)"	"unprognostic (3.51e-3)"	"unprognostic (3.59e-2)"	"unprognostic (1.89e-1)"	"unprognostic (2.94e-1)"	"unprognostic (2.97e-2)"	"unprognostic (9.52e-2)"	"unprognostic (4.29e-2)"	"unprognostic (9.91e-3)"	"unprognostic (6.89e-2)"	"unprognostic (5.73e-1)"	"unprognostic (1.59e-4)"	"unprognostic (2.02e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.16e-2)"
RETN	"ADSF, FIZZ3, RETN1"	ENSG00000104918	Resistin	Q9HD89	19	7669049-7670455	"Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins"		Hormone	"Diabetes mellitus, Obesity"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"bone marrow: 247.2"	"Group enriched"	"Detected in some"	9	"Hofbauer cells: 174.6;Kupffer cells: 78.9;Macrophages: 68.7;monocytes: 52.7"	"Group enriched"	"Detected in many"	4	"lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4"	"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	8	"classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4"	"Group enriched"	"Detected in many"	11	"dendritic cells: 118.7;monocytes: 170.4"	"Cancer enriched"	"Detected in single"	147	"Leukemia: 68.2"	"Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Neutrophils, Prostate - Macrophages, Thyroid - Neutrophils"	"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"								"Secreted to blood"	NA	NA	5120000	1200000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 19: Macrophages - Innate immune response"				"unprognostic (5.61e-2)"	"unprognostic (6.20e-3)"	"unprognostic (1.32e-2)"	"unprognostic (3.04e-1)"	"unprognostic (5.19e-4)"	"unprognostic (1.53e-4)"	"unprognostic (7.34e-2)"	"unprognostic (3.35e-2)"	"unprognostic (9.30e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.20e-1)"	"unprognostic (4.02e-1)"	"unprognostic (7.16e-5)"	"unprognostic (4.23e-2)"	"unprognostic (2.26e-1)"	"unprognostic (8.91e-2)"	"unprognostic (1.20e-1)"
S100A12	"CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6"	ENSG00000163221	"S100 calcium binding protein A12"	P80511	1	153373711-153375621	"Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Immunity, Inflammatory response, Innate immunity"	"Antibiotic, Antimicrobial, Fungicide"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	7	"bone marrow: 3489.7"	"Group enriched"	"Detected in many"	11	"Hofbauer cells: 394.8;Kupffer cells: 1324.3;Macrophages: 458.3"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 51.4"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	13	"classical monocyte: 1321.1;neutrophil: 1781.4"	"Group enriched"	"Detected in many"	13	"granulocytes: 1781.4;monocytes: 1321.1"	"Cancer enhanced"	"Detected in some"		"cervical cancer: 9.4;head and neck cancer: 7.2"	"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils"					"Region enhanced"	"Detected in some"		"cerebral cortex: 4.0"	"HPA002881, CAB025872"	Enhanced				"Secreted to blood"	NA	NA	28500000	8300000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 33: Macrophages - Degranulation"			"CAB025872: , HPA002881: AB_1848175"	"unprognostic (1.33e-1)"	"unprognostic (4.51e-2)"	"unprognostic (7.49e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.30e-2)"	"unprognostic (4.36e-2)"	"unprognostic (3.79e-2)"	"unprognostic (8.79e-3)"	"unprognostic (9.04e-2)"	"unprognostic (3.14e-2)"	"unprognostic (1.58e-1)"	"unprognostic (8.08e-3)"	"prognostic unfavorable (5.03e-4)"	"unprognostic (3.68e-3)"	"unprognostic (1.05e-1)"	"unprognostic (1.31e-2)"	"unprognostic (7.70e-2)"
S100A8	"60B8AG, CAGA, CFAG, CGLA, MRP8, P8"	ENSG00000143546	"S100 calcium binding protein A8"	P05109	1	153390032-153391073	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity"	Antimicrobial	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 9723.3;Kupffer cells: 12238.3;Squamous epithelial cells: 10710.7;Suprabasal keratinocytes: 41386.1"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 2290.9;head and neck cancer: 2382.0"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	9	"classical monocyte: 26833.7;neutrophil: 52973.6"	"Group enriched"	"Detected in all"	9	"granulocytes: 52973.6;monocytes: 26833.7"	"Group enriched"	"Detected in many"	8	"cervical cancer: 1388.9;head and neck cancer: 849.7"	"Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"CAB002791, HPA024372"	Enhanced		Supported	"Intermediate filaments,Cytosol"	"Secreted to blood"	NA	NA	10900000	370000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Intermediate filaments"	Cytosol	"CAB002791: , HPA024372: AB_1856536"	"unprognostic (1.98e-1)"	"unprognostic (1.13e-1)"	"unprognostic (3.79e-2)"	"unprognostic (1.58e-2)"	"unprognostic (8.60e-3)"	"unprognostic (9.26e-3)"	"unprognostic (4.92e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.83e-1)"	"unprognostic (6.13e-2)"	"unprognostic (3.77e-2)"	"unprognostic (2.24e-2)"	"prognostic unfavorable (8.94e-7)"	"unprognostic (1.17e-1)"	"unprognostic (8.90e-2)"	"unprognostic (8.27e-2)"	"unprognostic (8.94e-3)"
S100A9	"60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14"	ENSG00000163220	"S100 calcium binding protein A9"	P06702	1	153357854-153361023	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity"	"Antimicrobial, Antioxidant"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 11312.8;Hofbauer cells: 6740.0;Kupffer cells: 13272.6;Serous glandular cells: 7302.9;Suprabasal keratinocytes: 51664.6"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 5468.0;head and neck cancer: 6692.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	6	"classical monocyte: 24579.6;neutrophil: 33654.0"	"Group enriched"	"Detected in all"	6	"granulocytes: 33654.0;monocytes: 24579.6"	"Cancer enhanced"	"Detected in many"		"head and neck cancer: 1394.9"	"Breast - Macrophages, Colon - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA004193, CAB009441, CAB080262"	Enhanced		Supported	"Plasma membrane,Intermediate filaments,Cytosol"	"Secreted to blood"	NA	NA	10600000	1200000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 3: Suprabasal keratinocytes - Cornification"	"Plasma membrane, Intermediate filaments, Cytosol"		"CAB009441: AB_2184420, CAB080262: , HPA004193: AB_1856537"	"unprognostic (1.72e-1)"	"unprognostic (3.33e-2)"	"unprognostic (2.40e-1)"	"unprognostic (3.94e-3)"	"unprognostic (1.36e-2)"	"unprognostic (5.45e-3)"	"prognostic unfavorable (1.13e-6)"	"unprognostic (1.10e-2)"	"unprognostic (4.31e-1)"	"unprognostic (3.06e-1)"	"unprognostic (1.35e-2)"	"unprognostic (5.59e-2)"	"prognostic unfavorable (8.10e-4)"	"unprognostic (1.48e-1)"	"unprognostic (7.52e-2)"	"unprognostic (5.39e-2)"	"unprognostic (1.75e-2)"
S100P		ENSG00000163993	"S100 calcium binding protein P"	P25815	4	6693878-6697170	"Plasma proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0"	"Cell type enhanced"	"Detected in many"		"Club cells: 1882.4;Extravillous trophoblasts: 868.6;Gastric mucus-secreting cells: 2002.0;Ionocytes: 1013.7;Syncytiotrophoblasts: 2962.7"	"Cancer enhanced"	"Detected in many"		"urothelial cancer: 564.7"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	46	"basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8"	"Lineage enriched"	"Detected in many"	73	"granulocytes: 2961.8"	"Low cancer specificity"	"Detected in all"			"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Gastric mucous cells, Testis - Late spermatids, Thyroid - Neutrophils"									"HPA019502, HPA075251"	Enhanced		Supported	Nucleoplasm		NA	NA		1600000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Enzymes"	"Cluster 74: Pancreatic cells - Mixed function"	Nucleoplasm		"HPA019502: AB_1856530, HPA075251: "	"unprognostic (1.46e-1)"	"unprognostic (1.50e-1)"	"unprognostic (7.52e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.22e-1)"	"unprognostic (7.34e-2)"	"unprognostic (1.60e-3)"	"unprognostic (3.92e-2)"	"unprognostic (7.19e-2)"	"unprognostic (9.24e-2)"	"prognostic unfavorable (2.00e-4)"	"unprognostic (3.87e-2)"	"unprognostic (1.96e-2)"	"unprognostic (1.72e-1)"	"unprognostic (9.24e-2)"	"unprognostic (3.65e-1)"	"unprognostic (1.12e-2)"