Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ADGRF5	"DKFZp564O1923, GPR116, KIAA0758"	ENSG00000069122	"Adhesion G protein-coupled receptor F5"	Q8IZF2	6	46852522-46954943	"G-protein coupled receptors, Plasma proteins, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lung: 104.5"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 399.4;Alveolar cells type 1: 207.5;Alveolar cells type 2: 288.4;Endothelial cells: 221.8;Microglial cells: 101.2;Smooth muscle cells: 86.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Brain cancer: 5.7;lung cancer: 11.1;pancreatic cancer: 7.0"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA		55000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 66: Endothelial cells - Angiogenesis"				"unprognostic (8.45e-2)"	"unprognostic (3.00e-3)"	"unprognostic (1.13e-1)"	"unprognostic (3.26e-1)"	"unprognostic (6.51e-2)"	"unprognostic (1.89e-2)"	"unprognostic (5.76e-2)"	"unprognostic (9.00e-3)"	"unprognostic (7.80e-2)"	"unprognostic (3.32e-1)"	"unprognostic (1.42e-1)"	"unprognostic (4.56e-2)"	"prognostic favorable (8.84e-5)"	"unprognostic (1.43e-2)"	"unprognostic (5.91e-2)"	"unprognostic (2.82e-2)"	"unprognostic (3.78e-2)"
BCL6B	"BAZF, ZBTB28, ZNF62"	ENSG00000161940	"BCL6B transcription repressor"	Q8N143	17	7023050-7030290	"Predicted intracellular proteins, Transcription factors"				"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	5	"Adipocytes: 34.8;Endothelial cells: 38.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Leukemia: 2.3;ovarian cancer: 2.9"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA059147, HPA075112"	Uncertain		Approved	"Nucleoplasm,Vesicles,Plasma membrane"		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	Nucleoplasm	"Vesicles, Plasma membrane"	"HPA059147: AB_2683928, HPA075112: AB_2732279"	"unprognostic (5.61e-2)"	"unprognostic (9.43e-3)"	"unprognostic (2.33e-2)"	"unprognostic (2.12e-1)"	"unprognostic (1.40e-1)"	"prognostic favorable (8.56e-5)"	"unprognostic (2.81e-1)"	"unprognostic (2.28e-2)"	"unprognostic (4.81e-2)"	"unprognostic (1.80e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.76e-1)"	"prognostic unfavorable (4.04e-4)"	"unprognostic (7.14e-2)"	"unprognostic (1.11e-1)"	"unprognostic (4.29e-2)"	"unprognostic (4.26e-2)"
CDH5	"7B4, CD144"	ENSG00000179776	"Cadherin 5"	P33151	16	66366622-66404784	"Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 235.9"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 296.8;Endothelial cells: 212.8;Extravillous trophoblasts: 50.9;Late spermatids: 86.2;Syncytiotrophoblasts: 121.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"ovarian cancer: 13.1;Rhabdoid: 12.4"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB028366, HPA075875"	Approved		Supported	"Nucleoplasm,Nuclear membrane,Plasma membrane"		NA	NA		1300000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Plasma membrane"	"Nucleoplasm, Nuclear membrane"	"CAB028366: AB_2276033, HPA075875: "	"unprognostic (1.05e-1)"	"unprognostic (8.13e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.89e-2)"	"unprognostic (4.96e-2)"	"unprognostic (5.50e-3)"	"unprognostic (9.38e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.33e-2)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (5.14e-4)"	"unprognostic (9.49e-3)"	"unprognostic (3.01e-2)"	"unprognostic (2.22e-1)"	"unprognostic (3.15e-2)"
CLEC14A	C14orf27	ENSG00000176435	"C-type lectin domain containing 14A"	Q86T13	14	38254000-38256093	"Predicted membrane proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	7	"Adipocytes: 384.2;Endothelial cells: 325.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in single"	24	"Leukemia: 8.1"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039468, HPA048119"	Uncertain		Supported	"Endoplasmic reticulum,Golgi apparatus"		NA	NA		4100000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Endoplasmic reticulum, Golgi apparatus"		"HPA039468: AB_2676524, HPA048119: AB_2680270"	"unprognostic (4.02e-1)"	"unprognostic (4.26e-2)"	"unprognostic (4.20e-3)"	"unprognostic (9.44e-2)"	"unprognostic (1.35e-1)"	"prognostic favorable (4.13e-6)"	"unprognostic (2.55e-3)"	"unprognostic (2.69e-1)"	"unprognostic (1.67e-1)"	"unprognostic (6.90e-2)"	"unprognostic (5.41e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.63e-2)"	"unprognostic (1.75e-2)"	"unprognostic (1.55e-1)"	"unprognostic (4.97e-2)"	"unprognostic (5.28e-2)"
DIPK2B	"CXorf36, DIA1R, FLJ14103"	ENSG00000147113	"Divergent protein kinase domain 2B"	Q9H7Y0	X	45148373-45200901	"Disease related genes, Predicted secreted proteins"			"Autism, Autism spectrum disorder"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"Adipocytes: 173.4;Endothelial cells: 135.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA002806	Uncertain				"Secreted - unknown location"	NA	NA		940000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"			"HPA002806: AB_1078595"	"unprognostic (2.12e-1)"	"unprognostic (1.32e-2)"	"unprognostic (8.51e-3)"	"unprognostic (2.05e-1)"	"unprognostic (4.65e-2)"	"unprognostic (4.07e-3)"	"unprognostic (7.30e-2)"	"unprognostic (1.61e-1)"	"unprognostic (1.50e-1)"	"unprognostic (3.39e-1)"	"unprognostic (6.06e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.75e-3)"	"unprognostic (3.79e-3)"	"unprognostic (1.98e-1)"	"unprognostic (8.47e-2)"	"unprognostic (3.11e-2)"
ERG	"erg-3, p55"	ENSG00000157554	"ETS transcription factor ERG"	P11308	21	38380027-38661780	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 87.1;Endothelial cells: 103.9;granulocytes: 26.0;Microglial cells: 85.7"	"Cancer enriched"	"Detected in all"	4	"prostate cancer: 18.6"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	10	"Leukemia: 24.7;prostate cancer: 23.9"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018377, HPA046598"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	Nucleoplasm	Cytosol	"CAB018377: AB_675518, HPA046598: AB_2679715"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.18e-6)"	"unprognostic (6.44e-3)"	"unprognostic (8.64e-3)"	"unprognostic (5.65e-2)"	"unprognostic (1.91e-1)"	"unprognostic (9.03e-4)"	"unprognostic (4.30e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.29e-1)"	"unprognostic (3.42e-2)"	"unprognostic (2.89e-1)"	"prognostic unfavorable (3.94e-4)"	"unprognostic (4.31e-3)"	"unprognostic (3.88e-2)"	"unprognostic (2.64e-2)"	"unprognostic (5.63e-3)"
MMRN2	"EMILIN3, EndoGlyx-1, FLJ13465"	ENSG00000173269	"Multimerin 2"	Q9H8L6	10	86935540-86969481	"Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"	Angiogenesis			"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	7	"Adipocytes: 220.5;Endothelial cells: 134.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA020741			Approved	Vesicles	"Secreted to extracellular matrix"	NA	NA		84000000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	Vesicles		"HPA020741: AB_1848154"	"unprognostic (4.17e-1)"	"unprognostic (7.87e-2)"	"unprognostic (6.67e-3)"	"unprognostic (3.30e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.08e-2)"	"unprognostic (1.75e-3)"	"unprognostic (1.43e-1)"	"unprognostic (2.09e-2)"	"unprognostic (3.11e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.34e-1)"	"unprognostic (6.17e-3)"	"unprognostic (1.54e-3)"	"unprognostic (1.25e-1)"	"unprognostic (6.44e-2)"	"unprognostic (1.66e-1)"
ROBO4	"ECSM4, FLJ20798, MRB"	ENSG00000154133	"Roundabout guidance receptor 4"	Q8WZ75	11	124883691-124898500	"Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins"	"Angiogenesis, Differentiation"	"Developmental protein, Receptor"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	6	"Adipocytes: 174.0;Endothelial cells: 124.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Sarcoma: 4.2"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA065212			Approved	"Plasma membrane"		NA	NA		380000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Plasma membrane"		"HPA065212: AB_2685434"	"unprognostic (2.86e-1)"	"unprognostic (9.35e-2)"	"unprognostic (2.67e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.82e-2)"	"unprognostic (6.97e-2)"	"prognostic favorable (4.85e-4)"	"unprognostic (7.94e-2)"	"unprognostic (2.27e-1)"	"unprognostic (1.43e-1)"	"unprognostic (1.73e-3)"	"unprognostic (2.17e-1)"	"unprognostic (1.17e-2)"	"prognostic unfavorable (8.73e-4)"	"unprognostic (1.55e-1)"	"unprognostic (4.63e-1)"	"unprognostic (5.15e-2)"