Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.3;Basal respiratory cells: 7.1;Ionocytes: 6.4;Suprabasal keratinocytes: 33.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4, N-acyl phospholipase B" Q8TB40 14 22598237-22613215 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 35.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 35.4" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA000600: AB_1078081" "unprognostic (5.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.68e-3)" "unprognostic (8.17e-2)" "unprognostic (1.17e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-3)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.73e-1)" "unprognostic (1.56e-2)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" ADAT3 TAD3 ENSG00000213638 "Adenosine deaminase tRNA specific 3" 19 1905399-1913447 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 10.8;Gastric mucus-secreting cells: 7.8;Squamous epithelial cells: 12.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058899 Uncertain Approved Nucleoplasm No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 53: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA058899: AB_2683847" "unprognostic (1.79e-1)" "unprognostic (7.99e-2)" "unprognostic (1.57e-1)" "unprognostic (3.61e-3)" "unprognostic (4.43e-2)" "prognostic favorable (6.13e-4)" "unprognostic (1.48e-4)" "unprognostic (2.18e-1)" "unprognostic (1.63e-1)" "unprognostic (1.38e-1)" "unprognostic (4.78e-3)" "unprognostic (5.27e-2)" "unprognostic (2.21e-2)" "prognostic favorable (6.98e-4)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (9.55e-3)" ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 114.3;Basal respiratory cells: 78.0;Basal squamous epithelial cells: 58.9;Club cells: 53.8;Squamous epithelial cells: 237.5;Suprabasal keratinocytes: 203.9" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Esophageal cancer: 29.4;Gallbladder cancer: 98.7" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.7;Basal respiratory cells: 70.2;Basal squamous epithelial cells: 31.6;Langerhans cells: 31.8;Suprabasal keratinocytes: 36.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 193.7;Alveolar cells type 1: 120.6;Basal keratinocytes: 285.9;Basal respiratory cells: 139.6;Basal squamous epithelial cells: 176.7;granulocytes: 149.3;Squamous epithelial cells: 275.5;Suprabasal keratinocytes: 168.5" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 57.4" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075322 Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" AEBP2 MGC17922 ENSG00000139154 "AE binding protein 2" Q6ZN18 12 19404045-19720801 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020893, HPA022282" Uncertain Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA020893: AB_2670528, HPA022282: AB_2670931" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (9.15e-2)" "unprognostic (4.56e-2)" "unprognostic (5.19e-3)" "unprognostic (1.87e-1)" "unprognostic (3.45e-2)" "unprognostic (1.68e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" AHDC1 "DJ159A19.3, RP1-159A19.1" ENSG00000126705 "AT-hook DNA binding motif containing 1" Q5TGY3 1 27534035-27604431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028648, HPA028685, HPA028691" Approved Supported Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA028648: AB_10599276, HPA028685: , HPA028691: AB_10601781" "unprognostic (1.96e-1)" "unprognostic (1.73e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.43e-1)" "prognostic favorable (2.68e-4)" "unprognostic (9.20e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (5.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 137.7;Basal respiratory cells: 79.8;Horizontal cells: 166.0;Salivary duct cells: 70.1;Squamous epithelial cells: 73.4;Suprabasal keratinocytes: 243.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 388.0;Cholangiocytes: 196.3;Distal enterocytes: 190.9;Gastric mucus-secreting cells: 499.0;Proximal enterocytes: 373.1;Suprabasal keratinocytes: 540.4" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 2640.5;liver cancer: 687.1" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 551.9;Basal respiratory cells: 376.7;Basal squamous epithelial cells: 249.1;Gastric mucus-secreting cells: 424.5;Respiratory ciliated cells: 376.2;Serous glandular cells: 212.8;Squamous epithelial cells: 370.3;Suprabasal keratinocytes: 936.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 3235.6" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 249.0;Basal squamous epithelial cells: 284.7;Squamous epithelial cells: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" ANAPC7 APC7 ENSG00000196510 "Anaphase promoting complex subunit 7" Q9UJX3 12 110372900-110403730 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009567 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB009567: AB_2227137" "unprognostic (2.49e-1)" "unprognostic (1.42e-3)" "unprognostic (1.69e-2)" "unprognostic (2.36e-2)" "unprognostic (2.02e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (3.20e-1)" "unprognostic (7.08e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.36e-10)" "unprognostic (1.45e-1)" "unprognostic (9.92e-2)" "unprognostic (3.08e-2)" "unprognostic (1.58e-2)" ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.8;skin 1: 30.9;stomach 1: 46.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.2;Distal enterocytes: 31.8;Gastric mucus-secreting cells: 56.0;Paneth cells: 40.5;Squamous epithelial cells: 44.1;Suprabasal keratinocytes: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.0;Gallbladder cancer: 14.3" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA012922: AB_1844838" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (9.73e-3)" "prognostic favorable (8.73e-6)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (4.57e-2)" "unprognostic (7.21e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.09e-3)" "unprognostic (1.05e-2)" "unprognostic (4.87e-3)" "unprognostic (4.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.01e-3)" ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.3;Basal respiratory cells: 45.2;Excitatory neurons: 47.1;Inhibitory neurons: 40.0;Oligodendrocyte precursor cells: 48.6;Oligodendrocytes: 45.5;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 79.3;Thymic epithelial cells: 143.4" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "head and neck cancer: 250.6" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 24.5;Basal respiratory cells: 41.0;Basal squamous epithelial cells: 37.2;Squamous epithelial cells: 133.2;Suprabasal keratinocytes: 41.2;Thymic epithelial cells: 55.2" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 156.9;head and neck cancer: 228.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Skin - Keratinocyte (other)" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1573.3;Basal squamous epithelial cells: 1021.8;Collecting duct cells: 1086.9;Squamous epithelial cells: 2389.1;Suprabasal keratinocytes: 2174.6" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 392.4" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" ARF5 ENSG00000004059 "ADP ribosylation factor 5" P84085 7 127588386-127591700 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (6.72e-3)" "unprognostic (2.34e-2)" "unprognostic (1.67e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (5.81e-3)" "unprognostic (9.41e-2)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (7.02e-2)" "unprognostic (1.02e-1)" "unprognostic (9.69e-2)" "unprognostic (1.50e-1)" "unprognostic (1.26e-2)" "unprognostic (3.95e-1)" "unprognostic (2.46e-2)" ARHGEF19 "FLJ33962, WGEF" ENSG00000142632 "Rho guanine nucleotide exchange factor 19" Q8IW93 1 16197854-16212652 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068108 Approved "Nuclear bodies" No No "Cluster 22: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 56: Neurons - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA068108: AB_2685956" "unprognostic (2.19e-2)" "unprognostic (1.85e-3)" "unprognostic (1.33e-1)" "unprognostic (3.52e-2)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-2)" "prognostic favorable (6.53e-4)" "unprognostic (4.01e-2)" "unprognostic (2.43e-2)" "unprognostic (2.07e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.88e-5)" "unprognostic (3.72e-2)" "unprognostic (2.84e-1)" "unprognostic (1.26e-1)" "unprognostic (1.80e-1)" ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 236.1;Early spermatids: 215.0;Rod photoreceptor cells: 235.6;Squamous epithelial cells: 230.3;Suprabasal keratinocytes: 210.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.3;naive B-cell: 36.1" "Lineage enriched" "Detected in all" 4 "B-cells: 36.1" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 8.7;cerebral cortex: 8.8;hippocampal formation: 5.7;olfactory bulb: 4.2;spinal cord: 5.4" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "Golgi apparatus" "HPA060379: AB_2684269" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "prognostic favorable (1.16e-5)" "unprognostic (7.71e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.47e-1)" "unprognostic (4.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (7.87e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (9.25e-4)" ASB6 ENSG00000148331 "Ankyrin repeat and SOCS box containing 6" Q9NWX5 9 129634604-129642169 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004341 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA004341: AB_1845070" "unprognostic (1.60e-2)" "unprognostic (7.57e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (5.61e-2)" "unprognostic (1.99e-1)" "unprognostic (1.34e-2)" "unprognostic (7.68e-2)" "unprognostic (3.38e-3)" "unprognostic (1.95e-1)" "unprognostic (2.07e-2)" "unprognostic (3.74e-2)" "unprognostic (1.71e-1)" "unprognostic (8.00e-2)" ASCL5 bHLHa47 ENSG00000232237 "Achaete-scute family bHLH transcription factor 5" Q7RTU5 1 201113953-201127184 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 2.1" "Cell type enhanced" "Detected in single" "Exocrine glandular cells: 2.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.2" "Group enriched" "Detected in some" 5 "amygdala: 2.8;cerebral cortex: 2.1;hippocampal formation: 1.6" "Not detected" "Not detected" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (9.71e-2)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (6.32e-2)" "unprognostic (9.43e-2)" "unprognostic (8.04e-3)" "unprognostic (3.17e-2)" "unprognostic (2.37e-1)" "unprognostic (4.84e-2)" "unprognostic (9.50e-2)" "unprognostic (7.48e-2)" "unprognostic (9.82e-2)" "unprognostic (2.25e-7)" "unprognostic (2.95e-1)" "unprognostic (1.38e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-2)" ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 3.9;Spermatogonia: 3.4;Suprabasal keratinocytes: 7.5" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.7" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" ATG101 "C12orf44, FLJ11773" ENSG00000123395 "Autophagy related 101" Q9BSB4 12 52069246-52077494 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 261.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039904 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA039904: AB_10673262" "unprognostic (1.77e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (3.19e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (8.07e-7)" "unprognostic (9.39e-2)" "unprognostic (1.40e-1)" "unprognostic (5.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (3.63e-2)" "unprognostic (1.27e-1)" "unprognostic (1.89e-1)" "unprognostic (3.36e-1)" "unprognostic (1.15e-1)" B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235447190-235504452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007846, HPA050662" Approved Uncertain "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 47: Retina - Visual perception" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" "HPA007846: , HPA050662: AB_2681209" "unprognostic (5.50e-2)" "unprognostic (3.16e-3)" "unprognostic (6.60e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (7.59e-3)" "unprognostic (1.96e-2)" "unprognostic (3.39e-2)" "unprognostic (3.38e-1)" "unprognostic (7.19e-3)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (8.34e-3)" B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 149.0;Langerhans cells: 171.5;Squamous epithelial cells: 170.0;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Early spermatids" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" BAG3 ENSG00000151929 "BAG cochaperone 3" O95817 10 119651380-119677819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis Chaperone "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 349.1;skeletal muscle: 514.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 383.7;Cardiomyocytes: 225.9;Skeletal myocytes: 391.9;Squamous epithelial cells: 341.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Lineage enriched" "Detected in single" 6 "T-cells: 4.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018493, HPA020586" Enhanced Supported Nucleoplasm,Cytosol NA NA 460000 "Cluster 32: T-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA018493: AB_1845257, HPA020586: AB_1845258" "unprognostic (1.18e-1)" "unprognostic (1.68e-1)" "unprognostic (2.12e-2)" "unprognostic (1.17e-1)" "unprognostic (2.82e-2)" "unprognostic (5.31e-3)" "unprognostic (4.51e-3)" "unprognostic (3.32e-2)" "unprognostic (1.98e-2)" "unprognostic (1.46e-2)" "unprognostic (1.30e-2)" "unprognostic (1.49e-1)" "unprognostic (2.18e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.46e-2)" "unprognostic (3.03e-2)" BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.9;Mucus glandular cells: 104.5;Salivary duct cells: 52.6;Serous glandular cells: 63.8;Squamous epithelial cells: 198.1;Suprabasal keratinocytes: 161.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" BCL2L10 "BCL-B, Boo, Diva" ENSG00000137875 "BCL2 like 10" Q9HD36 15 52109263-52112775 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.6;skin 1: 6.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7.7;Basal squamous epithelial cells: 6.5;Proximal enterocytes: 12.3;Proximal tubular cells: 8.5;Squamous epithelial cells: 8.1;Suprabasal keratinocytes: 10.5" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA042222 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA042222: AB_10794271" "unprognostic (5.33e-4)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (3.22e-4)" "unprognostic (1.19e-2)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "unprognostic (4.80e-3)" "unprognostic (8.86e-2)" "unprognostic (3.47e-2)" "unprognostic (9.52e-2)" "unprognostic (3.83e-1)" "unprognostic (2.18e-9)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.92e-1)" "unprognostic (3.20e-2)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.4;Basal squamous epithelial cells: 30.2;Squamous epithelial cells: 20.6;Suprabasal keratinocytes: 23.5;Thymic epithelial cells: 25.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.6" "Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 95.2;Basal squamous epithelial cells: 91.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 127.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 466.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" HPA047390 Approved Nucleoli NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA047390: AB_2680025" "unprognostic (1.05e-2)" "unprognostic (7.91e-3)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.08e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (3.51e-1)" "unprognostic (4.45e-1)" "unprognostic (1.91e-3)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.96e-2)" "unprognostic (7.62e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.28e-5)" BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255903-83284714 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.0;esophagus: 12.5;testis: 30.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.3;Early spermatids: 42.0;Late spermatids: 99.2;Suprabasal keratinocytes: 39.8;Thymic epithelial cells: 98.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 31.0" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063183, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA063183: AB_2684957, HPA077428: AB_2732345" "unprognostic (1.86e-3)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (5.55e-2)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "unprognostic (2.45e-2)" "unprognostic (7.91e-2)" "unprognostic (8.89e-4)" "unprognostic (6.94e-2)" "unprognostic (4.13e-1)" "unprognostic (3.85e-3)" "unprognostic (8.46e-3)" "unprognostic (2.20e-1)" "unprognostic (2.95e-3)" "unprognostic (1.01e-2)" BX664615.2 ENSG00000283886 Q8NFD4 9 39816599-39874562 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.8;Pancreatic endocrine cells: 1.7;Thymic epithelial cells: 1.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA021733 Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA021733: AB_10602499" C1orf109 FLJ20508 ENSG00000116922 "Chromosome 1 open reading frame 109" Q9NX04 1 37681570-37692249 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027110, HPA027127" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Nucleoplasm, Nucleoli" "HPA027110: AB_10611813, HPA027127: AB_1845628" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (2.43e-1)" "unprognostic (3.30e-3)" "unprognostic (1.71e-2)" "unprognostic (7.13e-3)" "prognostic unfavorable (1.76e-7)" "unprognostic (1.93e-1)" "unprognostic (1.48e-2)" "unprognostic (8.38e-2)" "unprognostic (1.73e-1)" "unprognostic (3.79e-3)" "unprognostic (9.96e-2)" "unprognostic (1.66e-2)" "unprognostic (2.25e-1)" "unprognostic (7.96e-3)" "unprognostic (1.69e-1)" C1orf52 "FLJ44982, gm117" ENSG00000162642 "Chromosome 1 open reading frame 52" Q8N6N3 1 85249953-85259672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036072, HPA061790" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA036072: AB_10602696, HPA061790: AB_2684610" "unprognostic (1.59e-1)" "unprognostic (2.30e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.37e-5)" "unprognostic (6.67e-3)" "unprognostic (2.95e-2)" "unprognostic (3.73e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.93e-4)" "prognostic unfavorable (1.17e-7)" "unprognostic (8.01e-2)" "unprognostic (2.54e-1)" "unprognostic (4.14e-1)" "unprognostic (2.05e-2)" C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 35.9" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.4;Squamous epithelial cells: 27.5;Suprabasal keratinocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 465.1;Basal squamous epithelial cells: 281.5;Squamous epithelial cells: 1484.8;Suprabasal keratinocytes: 1171.9" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "cervical cancer: 108.0;Esophageal cancer: 88.0;head and neck cancer: 53.9;prostate cancer: 55.6" "Kidney - Proximal tubular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" CAPN14 ENSG00000214711 "Calpain 14" A8MX76 2 31173056-31233858 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "esophagus: 144.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.9;Excitatory neurons: 3.1;granulocytes: 3.3;Inhibitory neurons: 4.1;Squamous epithelial cells: 9.4" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 2.5" "Kidney - Endothelial cells" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (5.81e-3)" "unprognostic (1.20e-1)" "unprognostic (4.57e-2)" "unprognostic (1.88e-2)" "unprognostic (3.85e-2)" "unprognostic (3.30e-1)" "unprognostic (3.61e-2)" "unprognostic (4.67e-2)" "unprognostic (1.71e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" "unprognostic (1.60e-1)" "unprognostic (3.71e-4)" "unprognostic (8.42e-2)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (4.47e-4)" CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 85.7;skin 1: 102.4" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 134.7;Basal squamous epithelial cells: 96.5;Squamous epithelial cells: 112.6;Suprabasal keratinocytes: 230.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.3;urothelial cancer: 21.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Cancer enhanced" "Detected in some" "Esophageal cancer: 18.0;head and neck cancer: 17.6" "Prostate - Urothelial cells" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA059749: AB_2732639, HPA076768: AB_2732322" "unprognostic (3.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.77e-3)" "unprognostic (4.14e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (7.21e-2)" "unprognostic (3.38e-2)" "unprognostic (3.62e-1)" "unprognostic (2.42e-2)" "unprognostic (4.48e-1)" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 19.4;Suprabasal keratinocytes: 47.8" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "breast cancer: 18.1" "Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.3;salivary gland: 41.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 129.0;Basal respiratory cells: 107.5;Basal squamous epithelial cells: 125.0;Squamous epithelial cells: 238.3;Suprabasal keratinocytes: 184.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 23.9;NK-cells: 11.5;T-cells: 33.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 102.5" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA018434: AB_1846110" "unprognostic (3.64e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-2)" "unprognostic (3.75e-1)" "unprognostic (9.10e-2)" "prognostic unfavorable (5.95e-6)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.99e-3)" "unprognostic (1.94e-1)" CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052637, HPA053914" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoli, Mitotic chromosome" "HPA052637: AB_2681894, HPA053914: AB_2682306" "unprognostic (3.04e-1)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (3.07e-2)" "unprognostic (1.68e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (8.32e-4)" "unprognostic (2.21e-2)" "unprognostic (8.33e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (4.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-1)" "unprognostic (1.39e-1)" CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 22 "Basal keratinocytes: 72.1;Suprabasal keratinocytes: 98.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA073848: AB_2732243" CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.8" "Cell type enhanced" "Detected in many" "Horizontal cells: 51.3;Oligodendrocytes: 45.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 13.3;basal ganglia: 21.6;cerebral cortex: 44.6;hippocampal formation: 50.8;white matter: 26.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 21.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Excitatory neurons: 72.3;Inhibitory neurons: 68.9;Microglial cells: 92.1;Oligodendrocytes: 70.3;Suprabasal keratinocytes: 86.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Nucleoli "HPA021787: AB_1846524, HPA058945: AB_2683860" "unprognostic (5.48e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.20e-1)" "unprognostic (2.43e-3)" "unprognostic (2.64e-2)" "prognostic favorable (3.65e-4)" "unprognostic (4.88e-5)" "unprognostic (8.06e-2)" "unprognostic (3.51e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (6.68e-3)" "unprognostic (9.20e-8)" "unprognostic (1.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.04e-1)" CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 197.2;Suprabasal keratinocytes: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 125.2;Basal respiratory cells: 51.5;Basal squamous epithelial cells: 63.4;Club cells: 63.0;Squamous epithelial cells: 185.4;Suprabasal keratinocytes: 213.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 17.3;head and neck cancer: 33.1" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 309.8;skin 1: 288.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 275.1;Basal prostatic cells: 242.9;Basal respiratory cells: 212.0;Basal squamous epithelial cells: 211.0;Ductal cells: 201.0;Salivary duct cells: 241.9;Squamous epithelial cells: 294.6;Suprabasal keratinocytes: 483.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 25.4" "CAB002602, HPA048319" Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" CLDN20 ENSG00000171217 "Claudin 20" P56880 6 155264013-155276548 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.3;Excitatory neurons: 1.7;Inhibitory neurons: 1.6;Oligodendrocytes: 2.0;Schwann cells: 1.2;Sertoli cells: 2.8;Suprabasal keratinocytes: 1.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 6: Brain - Smell perception" "Cluster 52: Spermatids - Smell perception" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (2.84e-1)" "unprognostic (4.04e-2)" "unprognostic (2.38e-1)" "unprognostic (2.34e-2)" "unprognostic (1.67e-1)" "unprognostic (5.22e-2)" "unprognostic (6.26e-2)" "unprognostic (6.40e-2)" "unprognostic (7.33e-3)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (3.29e-2)" "unprognostic (2.05e-1)" CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.8;granulocytes: 6.5;Melanocytes: 3.5;Suprabasal keratinocytes: 18.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Leukemia: 7.4" "Skin - Keratinocyte (other)" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 677.3;Basal respiratory cells: 125.9;Basal squamous epithelial cells: 191.5;Distal enterocytes: 118.0;Salivary duct cells: 116.5;Suprabasal keratinocytes: 156.6" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 430.4" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.9;Basal respiratory cells: 59.2;Basal squamous epithelial cells: 44.3;Endometrial stromal cells: 39.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Endothelial cells" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" CRKL ENSG00000099942 "CRK like proto-oncogene, adaptor protein" P46109 22 20917407-20953747 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000532, HPA001100" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 39: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA000532: AB_2666019, HPA001100: AB_1078569" "unprognostic (5.54e-2)" "unprognostic (2.66e-1)" "unprognostic (5.87e-2)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-2)" "unprognostic (6.51e-2)" "unprognostic (2.35e-2)" "unprognostic (4.60e-1)" "unprognostic (2.71e-1)" "unprognostic (5.99e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (8.40e-2)" "unprognostic (1.43e-1)" "unprognostic (9.52e-2)" "unprognostic (1.61e-2)" CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.0;Squamous epithelial cells: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 238.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 341.7;Suprabasal keratinocytes: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Supported "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 196.9;esophagus: 242.0;skin 1: 301.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 236.9;Basal squamous epithelial cells: 310.7;Muller glia cells: 870.4;Squamous epithelial cells: 810.7;Suprabasal keratinocytes: 331.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "prostate cancer: 304.4" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: AB_2679870, HPA058635: AB_2732625" "unprognostic (3.95e-5)" "prognostic favorable (8.43e-4)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (8.59e-2)" "unprognostic (5.24e-2)" "unprognostic (4.59e-2)" "unprognostic (2.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-3)" "unprognostic (4.09e-2)" "unprognostic (6.68e-2)" "unprognostic (3.00e-2)" "unprognostic (2.30e-3)" DEFB126 "bA530N10.1, C20orf8, DEFB-26" ENSG00000125788 "Defensin beta 126" Q9BYW3 20 142590-145751 "Disease related genes, Predicted secreted proteins" Fertilization "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 297 "epididymis: 1285.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (3.16e-2)" "unprognostic (2.41e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" DENND2C "dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1" ENSG00000175984 "DENN domain containing 2C" Q68D51 1 114582848-114670422 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.7;skeletal muscle: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.0;Endometrial ciliated cells: 90.9;Glandular and luminal cells: 147.3;Skeletal myocytes: 131.6;Squamous epithelial cells: 118.2;Suprabasal keratinocytes: 186.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bone cancer: 10.9;Myeloma: 9.9" "Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029935, HPA054955" Uncertain Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 59: Non-specific - Translation" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA029935: AB_10601208, HPA054955: AB_2682648" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "unprognostic (9.97e-2)" "unprognostic (4.89e-4)" "unprognostic (1.52e-1)" "unprognostic (2.46e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (2.20e-2)" "unprognostic (7.43e-2)" "unprognostic (2.77e-2)" "unprognostic (2.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.57e-2)" DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4799.0" "Cell type enriched" "Detected in many" 8 "Suprabasal keratinocytes: 4521.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in all" "HPA029406, HPA071641" Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" NA NA 47000000 "Cluster 22: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA029406: AB_10603661, HPA071641: " "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" DR1 "NC2-BETA, NC2B, NCB2" ENSG00000117505 "Down-regulator of transcription 1" Q01658 1 93345907-93369493 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050785, HPA055308" Enhanced Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA050785: AB_2681237, HPA055308: AB_2682779" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.95e-7)" "unprognostic (8.70e-2)" "unprognostic (6.71e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.97e-1)" "unprognostic (1.60e-1)" DRAP1 NC2-alpha ENSG00000175550 "DR1 associated protein 1" Q14919 11 65919274-65921563 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 709.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006790 Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA006790: AB_1078702" "unprognostic (1.69e-2)" "unprognostic (1.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.84e-2)" "unprognostic (4.06e-2)" "unprognostic (4.89e-3)" "unprognostic (5.58e-2)" "unprognostic (8.47e-2)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.96e-5)" "unprognostic (1.62e-1)" DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 27.7;Suprabasal keratinocytes: 79.2" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Cancer enriched" "Detected in single" 9 "ovarian cancer: 7.8" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 528.1;Basal squamous epithelial cells: 320.1;Squamous epithelial cells: 413.8;Suprabasal keratinocytes: 609.7" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bladder cancer: 20.3;cervical cancer: 32.0;Esophageal cancer: 41.6;Gallbladder cancer: 15.2;head and neck cancer: 59.1" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 10 "Basal keratinocytes: 307.2;Suprabasal keratinocytes: 921.3" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 4.5" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 313.9;vagina: 119.1" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 375.1;Basal squamous epithelial cells: 571.8;Squamous epithelial cells: 1104.2;Suprabasal keratinocytes: 709.8" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.2" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.2" "Cancer enhanced" "Detected in many" "Esophageal cancer: 39.4;Gallbladder cancer: 45.8;head and neck cancer: 92.9" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2048.3;Cardiomyocytes: 1098.0;Squamous epithelial cells: 1850.5;Suprabasal keratinocytes: 4808.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1882.1;Basal squamous epithelial cells: 1760.3;Cardiomyocytes: 1396.3;Oligodendrocytes: 1331.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Lung - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 47: Retina - Visual perception" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056571 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 87.4;Basal keratinocytes: 87.8;Squamous epithelial cells: 52.3;Suprabasal keratinocytes: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavorable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 303.3;Suprabasal keratinocytes: 273.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 13: Non-specific - Nuclear processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.9;skin 1: 102.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 48.4;Basal squamous epithelial cells: 34.7;Extravillous trophoblasts: 34.5;Squamous epithelial cells: 31.3;Suprabasal keratinocytes: 95.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB010494: AB_2097783" "unprognostic (3.75e-2)" "unprognostic (1.53e-2)" "unprognostic (1.56e-2)" "unprognostic (1.51e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.86e-2)" "unprognostic (3.56e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.66e-10)" "unprognostic (2.83e-3)" "unprognostic (6.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 46.2;Suprabasal keratinocytes: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA001581: AB_2666367, HPA001790: " "unprognostic (9.58e-3)" "unprognostic (1.10e-2)" "unprognostic (3.68e-2)" "unprognostic (1.78e-1)" "unprognostic (6.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-1)" "unprognostic (3.85e-2)" "unprognostic (7.36e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.09e-5)" "unprognostic (3.44e-3)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.3;Gastric mucus-secreting cells: 4.2;Proximal enterocytes: 5.6;Squamous epithelial cells: 20.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cancer enriched" "Detected in many" 7 "lymphoma: 61.6" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.7;Breast glandular cells: 44.7;Breast myoepithelial cells: 51.0;Enteroendocrine cells: 42.4;Squamous epithelial cells: 44.1;Suprabasal keratinocytes: 55.6;Undifferentiated cells: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 63.5;Basal keratinocytes: 85.6;Suprabasal keratinocytes: 144.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" ERRFI1 "GENE-33, MIG-6, RALT" ENSG00000116285 "ERBB receptor feedback inhibitor 1" Q9UJM3 1 8004404-8026309 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 743.8;pancreas: 678.8" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 833.3;Hepatocytes: 687.0;Suprabasal keratinocytes: 416.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 5 "monocytes: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027206, HPA076543" Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA027206: AB_10600908, HPA076543: " "unprognostic (2.13e-3)" "unprognostic (1.01e-2)" "unprognostic (2.34e-1)" "unprognostic (1.71e-2)" "unprognostic (2.50e-3)" "unprognostic (1.66e-3)" "unprognostic (2.27e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.47e-1)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (1.19e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (8.03e-3)" EVPLL ENSG00000214860 "Envoplakin like" A8MZ36 17 18377778-18389647 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.9;skin 1: 6.0;vagina: 8.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.8;Gastric mucus-secreting cells: 2.4;Serous glandular cells: 2.2;Spermatogonia: 5.1;Squamous epithelial cells: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;Esophageal cancer: 1.9" HPA045728 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA045728: AB_10960394" "unprognostic (1.34e-1)" "unprognostic (4.88e-2)" "unprognostic (2.06e-5)" "unprognostic (1.58e-1)" "unprognostic (2.08e-2)" "unprognostic (1.64e-2)" "unprognostic (3.07e-1)" "unprognostic (3.62e-1)" "unprognostic (4.60e-4)" "unprognostic (5.28e-2)" "unprognostic (2.58e-1)" "unprognostic (1.43e-2)" "unprognostic (5.06e-2)" EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skin 1: 25.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 105.1;Endometrial ciliated cells: 73.4;Glandular and luminal cells: 84.9;Respiratory ciliated cells: 73.4;Suprabasal keratinocytes: 82.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 15 "cerebellum: 67.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in many" 8 "cerebellum: 30.9" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.34e-3)" "unprognostic (8.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (3.42e-6)" "unprognostic (2.91e-1)" "prognostic favorable (1.46e-4)" "unprognostic (4.57e-3)" "prognostic favorable (5.12e-4)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.36e-1)" "unprognostic (4.51e-1)" FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3968.3;Basal squamous epithelial cells: 2852.6;Hofbauer cells: 2239.5;Squamous epithelial cells: 10060.5;Suprabasal keratinocytes: 8043.7" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Basal squamous epithelial cells: 40.5;Squamous epithelial cells: 35.5;Suprabasal keratinocytes: 49.9;Syncytiotrophoblasts: 26.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.3" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.0;Basal squamous epithelial cells: 18.8;Late spermatids: 12.5;Squamous epithelial cells: 27.5;Suprabasal keratinocytes: 55.8" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 1.2;Esophageal cancer: 1.8;head and neck cancer: 3.5" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;testis: 40.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 45.7;Late spermatids: 65.9;Proximal enterocytes: 36.7;Suprabasal keratinocytes: 38.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 82.8;Basal squamous epithelial cells: 41.2;Squamous epithelial cells: 56.2;Suprabasal keratinocytes: 93.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 49: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504093-151568944 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.4;esophagus: 50.9;skin 1: 56.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 35.4;Basal respiratory cells: 31.1;Basal squamous epithelial cells: 34.5;Extravillous trophoblasts: 23.3;Serous glandular cells: 22.1;Squamous epithelial cells: 54.8;Suprabasal keratinocytes: 42.5" "Group enriched" "Detected in many" 6 "cervical cancer: 13.9;head and neck cancer: 21.4;lung cancer: 6.1;urothelial cancer: 5.6" "Region enriched" "Detected in many" 7 "cerebellum: 113.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 39.5;head and neck cancer: 57.9" "Testis - Late spermatids" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 56 "cerebellum: 224.4" "CAB033680, HPA044656" Enhanced Uncertain Vesicles NA NA 300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "CAB033680: AB_2100956, HPA044656: " "unprognostic (8.06e-3)" "unprognostic (6.01e-2)" "unprognostic (3.47e-1)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (4.43e-1)" "unprognostic (9.78e-3)" "unprognostic (2.28e-1)" "unprognostic (8.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-7)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (3.64e-3)" FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 28.5;Suprabasal keratinocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Vesicles" Cytosol "HPA049390: AB_2680742" "unprognostic (9.02e-3)" "unprognostic (1.01e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (9.33e-2)" "prognostic favorable (5.44e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" "prognostic favorable (8.11e-4)" "unprognostic (9.77e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (5.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (5.09e-6)" FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 916.0;Basal respiratory cells: 581.4;Ionocytes: 255.4;Squamous epithelial cells: 593.4;Suprabasal keratinocytes: 1270.5" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 368.5;head and neck cancer: 418.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 41.9;Squamous epithelial cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 57: Non-specific - Translation" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic spindle" "HPA043478: AB_2678500, HPA060158: AB_2684213" "unprognostic (1.80e-1)" "unprognostic (6.80e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-3)" "unprognostic (1.02e-1)" "unprognostic (7.67e-2)" "unprognostic (8.22e-3)" "unprognostic (2.25e-2)" "unprognostic (1.22e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-2)" "unprognostic (7.32e-2)" "unprognostic (4.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 7.0;Suprabasal keratinocytes: 26.9" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Brain cancer: 16.7;Kidney cancer: 22.1;ovarian cancer: 42.4;Uterine cancer: 40.4" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" FLG2 IFPS ENSG00000143520 "Filaggrin family member 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 483.9" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 13.9" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 61: Skin - Cornification" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" FOSL1 fra-1 ENSG00000175592 "FOS like 1, AP-1 transcription factor subunit" P15407 11 65892049-65900573 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.4;urinary bladder: 84.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 255.3;Basal squamous epithelial cells: 237.6;Squamous epithelial cells: 205.2;Suprabasal keratinocytes: 304.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 51.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.4" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB004396, HPA030728" Enhanced Supported Nucleoplasm NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB004396: AB_627632, HPA030728: " "unprognostic (2.88e-2)" "unprognostic (1.56e-1)" "unprognostic (9.46e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.80e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.26e-5)" "unprognostic (7.85e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (2.82e-2)" FOXE1 "FKHL15, FOXE2, HFKH4, TITF2, TTF-2" ENSG00000178919 "Forkhead box E1" O00358 9 97853226-97856717 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "thyroid gland: 194.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 9.0;Basal respiratory cells: 8.3;Basal squamous epithelial cells: 7.4;Ionocytes: 6.7;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 8.0" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 84.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 22.3" "Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.78e-3)" "unprognostic (9.18e-3)" "unprognostic (3.79e-5)" "unprognostic (2.19e-4)" "unprognostic (8.29e-3)" "unprognostic (1.04e-1)" "unprognostic (7.65e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-1)" "unprognostic (3.86e-1)" "unprognostic (6.05e-5)" "unprognostic (8.41e-2)" "unprognostic (1.86e-1)" "unprognostic (6.59e-2)" "unprognostic (1.45e-2)" FOXN1 "FKHL20, RONU, WHN" ENSG00000109101 "Forkhead box N1" O15353 17 28506243-28538900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 18.4;lymphoid tissue: 10.7;skin 1: 41.1;vagina: 10.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 10.1;Basal squamous epithelial cells: 4.7;Squamous epithelial cells: 18.0;Suprabasal keratinocytes: 23.4" "Cancer enhanced" "Detected in many" "cervical cancer: 7.0;head and neck cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 14.6;Esophageal cancer: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.60e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.68e-3)" "unprognostic (5.98e-6)" "prognostic favorable (5.00e-4)" "unprognostic (2.85e-1)" "unprognostic (2.56e-1)" "unprognostic (3.89e-2)" "unprognostic (7.08e-3)" "unprognostic (1.26e-2)" "unprognostic (1.90e-3)" "unprognostic (4.68e-2)" "unprognostic (3.96e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Lung - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 33: Skin cancer - Membrane components" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" FZD10 CD350 ENSG00000111432 "Frizzled class receptor 10" Q9ULW2 12 130162459-130165740 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 16.7;skin 1: 9.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.2;Basal squamous epithelial cells: 15.2;Smooth muscle cells: 6.8;Squamous epithelial cells: 27.9;Suprabasal keratinocytes: 13.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.0;head and neck cancer: 2.6" "Adipose subcutaneous - Smooth muscle cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "thalamus: 6.9" "Low region specificity" "Detected in many" "HPA014484, HPA014485" Uncertain Enhanced Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA014484: AB_1849132, HPA014485: AB_1849134" "unprognostic (2.41e-3)" "unprognostic (3.29e-1)" "unprognostic (4.74e-2)" "prognostic favorable (5.05e-7)" "unprognostic (2.81e-2)" "unprognostic (4.63e-2)" "unprognostic (8.62e-3)" "unprognostic (6.33e-2)" "unprognostic (5.41e-2)" "unprognostic (3.77e-2)" "unprognostic (2.70e-1)" "unprognostic (2.24e-3)" "unprognostic (2.66e-9)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.6;Suprabasal keratinocytes: 117.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Microtubules "CAB011825: AB_732515, HPA049473: AB_2680782" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (8.23e-2)" "unprognostic (2.51e-2)" "unprognostic (8.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-3)" "unprognostic (5.91e-3)" "unprognostic (3.12e-3)" "unprognostic (5.93e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-2)" "unprognostic (5.86e-2)" GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 418.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 77.8;skin 1: 145.0" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 100.0;Basal respiratory cells: 38.0;Basal squamous epithelial cells: 43.9;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 129.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.2" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 101.0;skin 1: 95.1;vagina: 35.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 55.3;Basal respiratory cells: 47.6;Basal squamous epithelial cells: 28.9;Squamous epithelial cells: 69.6;Suprabasal keratinocytes: 107.7" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 46.4;head and neck cancer: 56.3" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytokinetic bridge" "HPA023131: AB_2671080" "unprognostic (4.98e-2)" "unprognostic (2.69e-1)" "unprognostic (5.64e-3)" "unprognostic (1.65e-1)" "unprognostic (9.07e-2)" "unprognostic (2.71e-2)" "unprognostic (1.00e-2)" "unprognostic (4.57e-2)" "unprognostic (2.22e-1)" "unprognostic (2.65e-1)" "unprognostic (7.45e-3)" "unprognostic (5.03e-1)" "unprognostic (6.88e-3)" "unprognostic (4.61e-2)" "unprognostic (1.23e-1)" "unprognostic (3.21e-2)" "unprognostic (3.71e-3)" GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Melanocytes: 148.0;Oligodendrocytes: 387.8;Syncytiotrophoblasts: 190.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: NCI-H716 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 114.9;Squamous epithelial cells: 117.3;Syncytiotrophoblasts: 107.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 165.0;Esophageal cancer: 159.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Endothelial cells" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24319357-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 53.5;vagina: 47.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.8;Basal squamous epithelial cells: 30.5;Squamous epithelial cells: 126.5;Suprabasal keratinocytes: 109.5" "Group enriched" "Detected in many" 4 "cervical cancer: 13.3;head and neck cancer: 16.1;urothelial cancer: 28.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 47.5;testis cancer: 33.3" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059960: AB_2684180" "unprognostic (8.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.95e-2)" "unprognostic (7.83e-3)" "unprognostic (7.58e-3)" "unprognostic (6.28e-3)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (9.01e-3)" "unprognostic (4.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.36e-2)" "unprognostic (8.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (7.42e-2)" GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 41.5;Basal squamous epithelial cells: 27.8;Squamous epithelial cells: 29.8;Suprabasal keratinocytes: 45.8" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9;pancreatic cancer: 2.3" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "HPA026317, HPA072904" Supported Approved Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA026317: AB_1854008, HPA072904: " "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Mitochondria "HPA069369: AB_2686130" "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 120.8;Basal respiratory cells: 103.8;Squamous epithelial cells: 27.8;Suprabasal keratinocytes: 92.7" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 180.2" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 56.3;Basal prostatic cells: 156.2;Basal respiratory cells: 47.4;Basal squamous epithelial cells: 99.7;Langerhans cells: 142.8;Suprabasal keratinocytes: 66.4" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cancer enhanced" "Detected in many" "Bladder cancer: 20.9;Esophageal cancer: 22.9;head and neck cancer: 50.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.7;Basal prostatic cells: 192.2;Basal respiratory cells: 54.1;Basal squamous epithelial cells: 139.8;Langerhans cells: 72.1;Squamous epithelial cells: 45.9;Suprabasal keratinocytes: 87.8" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Group enriched" "Detected in some" 5 "Bladder cancer: 7.1;cervical cancer: 3.9;Esophageal cancer: 4.9;Gallbladder cancer: 6.6;head and neck cancer: 12.4" "Adipose visceral - Adipocytes (Visceral), Lung - NK-cells (Lung), Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" HEPHL1 DKFZp686F22190 ENSG00000181333 "Hephaestin like 1" Q6MZM0 11 94021354-94114208 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 4.5;lymphoid tissue: 9.5;skin 1: 3.8;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.1;granulocytes: 4.9;Serous glandular cells: 22.4;Suprabasal keratinocytes: 6.7" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 4.6;colorectal cancer: 4.1;head and neck cancer: 9.9" "Region enriched" "Detected in single" 12 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA031517 Uncertain NA NA 260000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA031517: AB_10603769" "unprognostic (9.16e-2)" "prognostic unfavorable (4.94e-4)" "unprognostic (2.40e-1)" "unprognostic (3.26e-6)" "unprognostic (3.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-2)" "unprognostic (6.71e-2)" "unprognostic (5.34e-1)" "unprognostic (1.09e-1)" "unprognostic (7.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" HES2 bHLHb40 ENSG00000069812 "Hes family bHLH transcription factor 2" Q9Y543 1 6412418-6424670 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 33.7;skin 1: 16.9;vagina: 18.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.3;Intestinal goblet cells: 41.1;Late spermatids: 46.7;Paneth cells: 39.2;Squamous epithelial cells: 62.7;Suprabasal keratinocytes: 43.7;Syncytiotrophoblasts: 114.4" "Cancer enhanced" "Detected in many" "cervical cancer: 17.0;head and neck cancer: 16.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 3.0;neutrophil: 1.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 35.3;head and neck cancer: 46.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA039462 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA039462: AB_10673533" "unprognostic (1.96e-1)" "unprognostic (7.00e-2)" "unprognostic (1.66e-1)" "unprognostic (6.82e-3)" "unprognostic (1.13e-2)" "unprognostic (1.89e-1)" "unprognostic (2.56e-4)" "unprognostic (4.74e-2)" "unprognostic (7.41e-2)" "unprognostic (3.20e-2)" "unprognostic (5.63e-3)" "unprognostic (1.38e-1)" "unprognostic (7.67e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-2)" HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Breast myoepithelial cells: 4.3;Melanocytes: 1.7;Spermatogonia: 1.6;Suprabasal keratinocytes: 2.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537287 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 203.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB002015: , HPA049830: AB_2680903, HPA070222: " "unprognostic (3.06e-2)" "unprognostic (2.98e-2)" "unprognostic (7.01e-2)" "unprognostic (3.08e-3)" "unprognostic (3.49e-3)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (9.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 7045.5;Squamous epithelial cells: 6860.6;Suprabasal keratinocytes: 4885.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Skin - Keratinocyte (other), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: RS4;11 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 127.9;Salivary duct cells: 57.5;Suprabasal keratinocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 27.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Basal respiratory cells: 1.5;Exocrine glandular cells: 1.3;Late spermatids: 1.2;Suprabasal keratinocytes: 4.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 202.3" HPA062776 Uncertain "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA062776: AB_2684866" "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" IGSF3 "EWI-3, MGC117164, V8" ENSG00000143061 "Immunoglobulin superfamily member 3" O75054 1 116574399-116667755 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036305, HPA036306" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA036305: AB_2675050, HPA036306: AB_10671245" "unprognostic (9.87e-2)" "unprognostic (3.64e-1)" "unprognostic (9.51e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.97e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (4.03e-6)" "unprognostic (9.40e-2)" "unprognostic (4.41e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.87e-6)" "unprognostic (5.29e-2)" "unprognostic (4.23e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 58.6;Basal respiratory cells: 113.8;Basal squamous epithelial cells: 53.5;Club cells: 30.1;Early spermatids: 65.4;Ionocytes: 46.7;Late spermatids: 32.6;Squamous epithelial cells: 58.9;Suprabasal keratinocytes: 103.5" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 90.8;head and neck cancer: 92.5" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 1.5;granulocytes: 1.6;Late spermatids: 1.6;Prostatic glandular cells: 2.2;Spermatocytes: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 31.6" "Cell type enhanced" "Detected in many" "Late spermatids: 36.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.28e-4)" IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 294.3;Basal squamous epithelial cells: 234.7;Squamous epithelial cells: 241.8;Suprabasal keratinocytes: 376.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 129.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" IRX4 ENSG00000113430 "Iroquois homeobox 4" P78413 5 1877413-1887236 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.8;heart muscle: 14.3;skin 1: 22.5;vagina: 12.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 38.5;Basal squamous epithelial cells: 48.6;Breast myoepithelial cells: 18.9;Salivary duct cells: 20.9;Squamous epithelial cells: 19.2;Suprabasal keratinocytes: 14.6" "Group enriched" "Detected in many" 5 "cervical cancer: 5.4;head and neck cancer: 7.3;lung cancer: 1.8;prostate cancer: 6.9;testis cancer: 7.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 7.1;head and neck cancer: 8.8;prostate cancer: 5.7" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "medulla oblongata: 1.2;pons: 1.5" HPA064094 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Vesicles" "HPA064094: " "unprognostic (1.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (7.52e-2)" "unprognostic (7.54e-2)" "unprognostic (4.26e-1)" "unprognostic (1.70e-2)" ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1900000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA070307: AB_2686249" "unprognostic (1.67e-1)" "unprognostic (4.46e-2)" "unprognostic (1.29e-1)" "unprognostic (6.42e-3)" "unprognostic (3.87e-2)" "unprognostic (1.91e-1)" "unprognostic (6.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.47e-1)" "unprognostic (4.19e-2)" "unprognostic (2.00e-2)" "unprognostic (4.18e-1)" "unprognostic (7.09e-3)" "unprognostic (2.49e-1)" "unprognostic (2.65e-1)" "unprognostic (1.65e-2)" "unprognostic (1.32e-2)" ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717112-40740860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 96.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 172.3;Gastric mucus-secreting cells: 150.8;Glandular and luminal cells: 130.5;Squamous epithelial cells: 169.7;Suprabasal keratinocytes: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" No No "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear speckles" "HPA050760: AB_2681227, HPA053003: AB_2682011" "unprognostic (4.27e-2)" "unprognostic (3.73e-2)" "unprognostic (8.31e-2)" "unprognostic (9.12e-3)" "unprognostic (1.10e-2)" "unprognostic (9.81e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (4.91e-4)" "unprognostic (1.48e-1)" "unprognostic (1.54e-3)" "unprognostic (1.84e-3)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.45e-2)" "unprognostic (3.32e-1)" ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 96.4;Basal squamous epithelial cells: 81.8;Squamous epithelial cells: 146.9;Suprabasal keratinocytes: 94.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 380.1;Squamous epithelial cells: 357.9;Suprabasal keratinocytes: 860.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 110.8;Suprabasal keratinocytes: 180.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 22: Squamous epithelial cells - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 863.2;Glandular and luminal cells: 661.0;Squamous epithelial cells: 1008.3;Suprabasal keratinocytes: 685.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" KLF8 "BKLF3, DXS741, ZNF741" ENSG00000102349 "Kruppel like factor 8" O95600 X 56232356-56291531 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 29.4" "Cell type enhanced" "Detected in many" "Leydig cells: 48.9;Peritubular cells: 34.9;Squamous epithelial cells: 35.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071740 Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA071740: AB_2686440" "unprognostic (2.32e-1)" "unprognostic (1.56e-1)" "unprognostic (3.60e-2)" "unprognostic (1.50e-8)" "unprognostic (2.96e-1)" "prognostic favorable (3.32e-4)" "unprognostic (6.56e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (6.13e-2)" "unprognostic (3.15e-1)" "unprognostic (6.83e-2)" "unprognostic (1.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.15e-1)" "unprognostic (7.68e-2)" "unprognostic (2.60e-2)" KLHL21 KIAA0469 ENSG00000162413 "Kelch like family member 21" Q9UJP4 1 6590724-6614607 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 169.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 83.7;Basal squamous epithelial cells: 79.5;Squamous epithelial cells: 98.8;Suprabasal keratinocytes: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 21.4;neutrophil: 63.0" "Lineage enriched" "Detected in all" 8 "granulocytes: 63.0" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051364, HPA059307" Uncertain Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Centrosome "HPA051364: AB_2681455, HPA059307: " "unprognostic (6.13e-3)" "unprognostic (5.26e-2)" "unprognostic (2.30e-2)" "unprognostic (9.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.39e-2)" "unprognostic (5.77e-3)" "unprognostic (2.28e-1)" "unprognostic (8.52e-2)" "unprognostic (4.85e-2)" "unprognostic (4.02e-1)" "unprognostic (6.33e-3)" "prognostic favorable (1.71e-4)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (9.74e-2)" "unprognostic (4.19e-2)" KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Group enriched" "Detected in some" 7 "Mucus glandular cells: 195.1;Salivary duct cells: 91.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 62.1;head and neck cancer: 37.3;ovarian cancer: 32.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 85.9;Squamous epithelial cells: 25.4;Suprabasal keratinocytes: 150.8;Thymic epithelial cells: 38.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 92.5;head and neck cancer: 83.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" KLRG2 "CLEC15B, FLJ44186" ENSG00000188883 "Killer cell lectin like receptor G2" A4D1S0 7 139452690-139483673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0;salivary gland: 4.3;thyroid gland: 4.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 7.0;Basal squamous epithelial cells: 9.6;Collecting duct cells: 5.9;Erythroid cells: 4.3;Squamous epithelial cells: 14.1;Syncytiotrophoblasts: 6.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 42.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.4" "Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018199 Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA018199: AB_2133260" "unprognostic (2.50e-2)" "unprognostic (3.05e-2)" "unprognostic (9.82e-2)" "unprognostic (5.38e-8)" "unprognostic (2.41e-1)" "unprognostic (1.97e-2)" "unprognostic (3.13e-2)" "prognostic favorable (8.61e-4)" "unprognostic (2.14e-2)" "unprognostic (2.92e-1)" "unprognostic (5.19e-2)" "unprognostic (8.83e-2)" "unprognostic (1.10e-3)" "unprognostic (5.66e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-2)" "unprognostic (2.34e-2)" KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 13006.6" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 6421.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 5 "Bladder cancer: 10.7;cervical cancer: 8.6;Esophageal cancer: 22.3;head and neck cancer: 15.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 8 "Suprabasal keratinocytes: 7021.9" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cervical cancer: 174.8;Rhabdoid: 207.7" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 28554.7;Suprabasal keratinocytes: 10747.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 2378.5" "Breast - Breast myoepithelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1641.1;Basal respiratory cells: 1142.9;Basal squamous epithelial cells: 8450.6;Squamous epithelial cells: 3518.4" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "cervical cancer: 1216.0;head and neck cancer: 559.1" "Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.2;esophagus: 1025.8;skin 1: 360.7;vagina: 489.4" "Group enriched" "Detected in many" 8 "Basal keratinocytes: 5666.1;Serous glandular cells: 2412.5;Suprabasal keratinocytes: 9213.6" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 132.5;head and neck cancer: 382.7" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 27 "Suprabasal keratinocytes: 132.3" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" CAB037321 Enhanced NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 56: Neurons - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB037321: " "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 284.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 32.7;Basal squamous epithelial cells: 18.6;Endometrial ciliated cells: 7.5;Glandular and luminal cells: 11.8;Squamous epithelial cells: 16.8;Suprabasal keratinocytes: 19.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "HPA049550, HPA055194" Enhanced NA NA 440000000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA049550: AB_2680813, HPA055194: AB_2682733" "unprognostic (3.92e-2)" "unprognostic (3.50e-1)" "unprognostic (3.30e-1)" "unprognostic (5.51e-2)" "unprognostic (7.71e-2)" "unprognostic (4.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (4.07e-1)" "unprognostic (4.26e-2)" "unprognostic (1.65e-1)" KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.9;skin 1: 19.5" "Cell type enriched" "Detected in some" 6 "Basal squamous epithelial cells: 18.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.0;colorectal cancer: 1.3" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 31: Skin - Epidermis development" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" KRT33A "Ha-3I, Krt1-3, KRTHA3A" ENSG00000006059 "Keratin 33A" O76009 17 41346092-41350828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 47.5" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 1.8;Late spermatids: 1.3;Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA055194 Supported NA NA 160000000 "Cluster 61: Skin - Cornification" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA055194: AB_2682733" "unprognostic (1.93e-1)" "unprognostic (1.30e-2)" "unprognostic (4.58e-2)" "unprognostic (4.34e-1)" "unprognostic (2.16e-1)" KRT36 KRTHA6 ENSG00000126337 "Keratin 36" O76013 17 41486136-41492546 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.5;skin 1: 1.7" "Cell type enriched" "Detected in some" 30 "Suprabasal keratinocytes: 386.4" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA 180000000 "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (4.39e-2)" "unprognostic (2.24e-3)" "unprognostic (9.85e-2)" "unprognostic (4.66e-1)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.34e-1)" "unprognostic (5.36e-2)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (7.19e-2)" "unprognostic (8.24e-2)" "unprognostic (8.50e-2)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (1.49e-1)" "unprognostic (7.11e-2)" KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 7218.7;Basal squamous epithelial cells: 2608.7;Squamous epithelial cells: 4419.2;Suprabasal keratinocytes: 2594.7" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in many" 4 "cervical cancer: 3110.2;Esophageal cancer: 1838.6;head and neck cancer: 3851.1" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479, CAB080101" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , CAB080101: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 9.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" KRT84 "Hb-4, KRTHB4" ENSG00000161849 "Keratin 84" Q9NSB2 12 52377812-52385652 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.5;skin 1: 1.9" "Cell type enriched" "Detected in single" 34 "Suprabasal keratinocytes: 16.2" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cervical cancer: 15.7;head and neck cancer: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA039714 Supported NA NA 67000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA039714: AB_2676641" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" KRTAP11-1 KAP11.1 ENSG00000182591 "Keratin associated protein 11-1" Q8IUC1 21 30880644-30881580 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "skin 1: 194.2" "Group enriched" "Detected in some" 30 "Basal keratinocytes: 4.0;Serous glandular cells: 4.5;Suprabasal keratinocytes: 2.9" "Group enriched" "Detected in some" 9 "endometrial cancer: 1.3;urothelial cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054008 Enhanced NA NA 2700000 "Cluster 61: Skin - Cornification" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA054008: AB_2682341" KRTAP13-1 KAP13.1 ENSG00000198390 "Keratin associated protein 13-1" Q8IUC0 21 30396031-30396822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "skin 1: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 1400000 "Cluster 61: Skin - Cornification" "Cluster 22: Squamous epithelial cells - Keratinization" KRTAP3-1 KAP3.1 ENSG00000212901 "Keratin associated protein 3-1" Q9BYR8 17 41008521-41019324 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 327 "skin 1: 231.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.5;Basal squamous epithelial cells: 4.5;Endometrial ciliated cells: 4.9;Glandular and luminal cells: 3.2;granulocytes: 4.9;Serous glandular cells: 6.7" "Cancer enhanced" "Detected in some" "stomach cancer: 2.8;urothelial cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 16.7;colorectal cancer: 9.1" "Skin - Hair cortex cells" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (4.24e-1)" "unprognostic (3.00e-2)" "unprognostic (7.37e-2)" KRTAP3-2 KAP3.2 ENSG00000212900 "Keratin associated protein 3-2" Q9BYR7 17 40999193-40999906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 107.6" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 2.9;Squamous epithelial cells: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "colorectal cancer: 2.0" "Skin - Hair cortex cells" HPA042992 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 2: DU4475 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA042992: AB_2678258" LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 38.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 31.7;Basal squamous epithelial cells: 25.8;Early spermatids: 13.2;Late spermatids: 11.3;Suprabasal keratinocytes: 11.9" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.8;Uterine cancer: 2.8" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA020242: AB_2670388, HPA024247: AB_2671496" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (4.85e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (6.29e-4)" "unprognostic (8.90e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-4)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 269.6" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 18.1" "Cancer enriched" "Detected in some" 6 "melanoma: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "head and neck cancer: 1.7" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 167.5" "Cell type enriched" "Detected in single" 21 "Suprabasal keratinocytes: 9.8" "Cancer enriched" "Detected in some" 10 "melanoma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.6" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "unprognostic (6.43e-2)" LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804835-152806628 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 596.1" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 10.4;Suprabasal keratinocytes: 37.2" "Cancer enriched" "Detected in some" 6 "melanoma: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.6;head and neck cancer: 2.8" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "skin 1: 61.4" "Cell type enriched" "Detected in single" 14 "Suprabasal keratinocytes: 6.8" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.5;colorectal cancer: 1.2" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (9.92e-2)" "unprognostic (9.50e-2)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152776372-152776728 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 209.8" "Cell type enriched" "Detected in single" 27 "Suprabasal keratinocytes: 2.9" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 3.1;head and neck cancer: 9.6;thyroid cancer: 2.8" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 719.8" "Cell type enriched" "Detected in single" 141 "Suprabasal keratinocytes: 14.1" "Cancer enriched" "Detected in some" 5 "melanoma: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "head and neck cancer: 3.2" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675295-152676574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 321.2" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 7.0" "Cancer enriched" "Detected in some" 5 "melanoma: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.8" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.47e-2)" "unprognostic (7.00e-2)" LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 152.1" "Cell type enriched" "Detected in single" 9 "Suprabasal keratinocytes: 2.4" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "head and neck cancer: 1.1" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 91.5" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Melanocytes: 1.7;Suprabasal keratinocytes: 3.6" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (2.51e-1)" "unprognostic (7.27e-3)" "unprognostic (9.27e-2)" "unprognostic (1.89e-1)" LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 246.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" HPA046376 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA046376: AB_10965998" "unprognostic (4.25e-2)" "unprognostic (8.73e-2)" LGALS7 "GAL7, LGALS7A, PIG1, TP53I1" ENSG00000205076 "Galectin 7" P47929 19 38770971-38773492 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 393.1;skin 1: 877.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 246.7;Basal squamous epithelial cells: 207.0;Squamous epithelial cells: 710.4;Suprabasal keratinocytes: 1081.6" "Group enriched" "Detected in many" 7 "cervical cancer: 32.0;head and neck cancer: 64.8;melanoma: 27.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Esophageal cancer: 11.9;head and neck cancer: 13.3" "Low region specificity" "Detected in single" "HPA001549, CAB032606" Enhanced "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB032606: AB_640852, HPA001549: AB_1078938" "unprognostic (1.56e-2)" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (4.86e-2)" "unprognostic (2.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.01e-2)" "unprognostic (3.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.31e-2)" "unprognostic (3.09e-2)" LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 1332.9;Suprabasal keratinocytes: 2929.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 5.4;Esophageal cancer: 2.3;head and neck cancer: 8.1;liver cancer: 2.1" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.0" "Cell type enhanced" "Detected in single" "Thymic epithelial cells: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "skin 1: 1842.9" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 91.4" "Cancer enriched" "Detected in some" 11 "melanoma: 45.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.5" "Skin - Keratinocyte (granular)" "HPA076123, HPA077266" Enhanced NA NA 1800000 "Cluster 61: Skin - Cornification" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA076123: AB_2732302, HPA077266: AB_2732338" "unprognostic (1.97e-2)" "unprognostic (1.93e-2)" "unprognostic (4.16e-2)" "prognostic favorable (8.53e-4)" "unprognostic (1.65e-1)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-2)" LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.8;Basal prostatic cells: 97.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: AB_10600755, HPA065840: " "unprognostic (1.09e-1)" "unprognostic (5.60e-2)" "unprognostic (5.79e-2)" "unprognostic (3.85e-5)" "unprognostic (3.93e-2)" "unprognostic (3.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.66e-3)" "unprognostic (7.74e-2)" "unprognostic (2.84e-1)" "prognostic favorable (7.46e-5)" "unprognostic (8.36e-2)" "unprognostic (4.28e-3)" "unprognostic (8.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-3)" "unprognostic (2.06e-1)" LRRC8A "FLJ10337, KIAA1437, LRRC8, SWELL1" ENSG00000136802 "Leucine rich repeat containing 8 VRAC subunit A" Q8IWT6 9 128882133-128918039 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (6.33e-2)" "unprognostic (3.88e-2)" "unprognostic (1.88e-3)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "unprognostic (4.38e-3)" "unprognostic (4.29e-2)" "unprognostic (1.19e-3)" "unprognostic (2.44e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (3.83e-4)" "unprognostic (3.53e-1)" "prognostic favorable (5.27e-5)" "unprognostic (3.69e-1)" "unprognostic (8.77e-2)" "unprognostic (3.93e-3)" "unprognostic (1.02e-2)" LRRC8E FLJ23420 ENSG00000171017 "Leucine rich repeat containing 8 VRAC subunit E" Q6NSJ5 19 7888505-7902021 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 12.3;Glandular and luminal cells: 12.7;Squamous epithelial cells: 11.8;Suprabasal keratinocytes: 15.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020466 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA020466: AB_1853352" "unprognostic (3.79e-2)" "unprognostic (2.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-3)" "unprognostic (8.28e-3)" "unprognostic (7.64e-2)" "unprognostic (1.71e-2)" "unprognostic (3.36e-1)" "unprognostic (8.38e-2)" "unprognostic (3.98e-6)" "unprognostic (1.11e-1)" "unprognostic (2.30e-2)" "unprognostic (3.29e-2)" "unprognostic (3.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-1)" LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.1;skin 1: 110.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.4;Kupffer cells: 60.4;Suprabasal keratinocytes: 95.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 100.3" "Group enriched" "Detected in many" 6 "granulocytes: 100.3;monocytes: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" HPA003873 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA003873: AB_1078288" "unprognostic (4.07e-2)" "unprognostic (7.67e-2)" "unprognostic (3.67e-3)" "unprognostic (2.40e-3)" "unprognostic (4.90e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "prognostic favorable (1.85e-4)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (2.88e-1)" "unprognostic (2.97e-1)" "unprognostic (6.59e-2)" "unprognostic (7.45e-2)" LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 37.7;skin 1: 46.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.7;Basal squamous epithelial cells: 15.9;Squamous epithelial cells: 16.2;Suprabasal keratinocytes: 25.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 2241.6;Squamous epithelial cells: 2076.7;Suprabasal keratinocytes: 5267.4" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 368.3;head and neck cancer: 354.4" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715356-31717804 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 24.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 39 "colorectal cancer: 8.9" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 6.1" HPA054412 Uncertain "Intracellular and membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 124.1;Excitatory neurons: 61.3;Inhibitory neurons: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: AB_10601869, HPA030833: AB_2673628" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (6.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (9.84e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.08e-3)" "unprognostic (6.03e-3)" "unprognostic (7.94e-2)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708395 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Suprabasal keratinocytes: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA035589: AB_10601870, HPA035590: AB_2674693" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favorable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" MED21 "SRB7, SURB7" ENSG00000152944 "Mediator complex subunit 21" Q13503 12 27022546-27066343 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 234.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017177 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Cytosol" "HPA017177: AB_1857665" "unprognostic (3.02e-1)" "unprognostic (7.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (7.18e-3)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" "unprognostic (7.32e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.74e-8)" "unprognostic (3.18e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-2)" MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 459.1;Proximal enterocytes: 450.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "Mindbomb E3 ubiquitin protein ligase 2" Q96AX9 1 1615415-1630610 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 44.0" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 118.0;Late spermatids: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA068322: AB_2685973" "unprognostic (3.93e-2)" "unprognostic (6.02e-2)" "unprognostic (2.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.17e-2)" "unprognostic (2.22e-3)" "unprognostic (1.29e-1)" "unprognostic (3.58e-2)" "unprognostic (2.49e-1)" "unprognostic (1.01e-2)" MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.4;Syncytiotrophoblasts: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 294.4;Basal respiratory cells: 269.4;Glandular and luminal cells: 182.6;Squamous epithelial cells: 371.0;Suprabasal keratinocytes: 444.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" MT4 MTIV ENSG00000102891 "Metallothionein 4" P47944 16 56565073-56568957 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "skin 1: 124.2" "Group enriched" "Detected in some" 10 "Basal keratinocytes: 29.2;granulocytes: 11.4;Serous glandular cells: 15.6;Suprabasal keratinocytes: 13.4" "Group enriched" "Detected in many" 6 "cervical cancer: 6.7;endometrial cancer: 11.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "colorectal cancer: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 61: Skin - Cornification" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.81e-2)" MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 53: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 608.5;Basal squamous epithelial cells: 1003.2;Squamous epithelial cells: 684.3;Suprabasal keratinocytes: 640.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.7;dendritic cells: 36.6;Squamous epithelial cells: 34.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 4 "lung cancer: 60.5;Myeloma: 32.5" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 80.8;Suprabasal keratinocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 255.4;Late spermatids: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 534.1;Proximal enterocytes: 394.4;Suprabasal keratinocytes: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.0;Granulosa cells: 67.1;Squamous epithelial cells: 110.7;Suprabasal keratinocytes: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 127.5" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" NIPAL4 ICHYN ENSG00000172548 "NIPA like domain containing 4" Q0D2K0 5 157460213-157474722 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" Receptor "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7;skin 1: 61.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 24.1;Oligodendrocytes: 19.8;Squamous epithelial cells: 9.0;Suprabasal keratinocytes: 37.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.0;urothelial cancer: 11.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 25 "memory B-cell: 1.6;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 37 "B-cells: 4.8" "Cancer enhanced" "Detected in many" "Bladder cancer: 10.7;head and neck cancer: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038259 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA038259: AB_10672510" "unprognostic (6.74e-4)" "unprognostic (9.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.49e-1)" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (3.55e-2)" "unprognostic (5.20e-2)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (5.28e-9)" "unprognostic (3.12e-2)" "unprognostic (8.66e-3)" "unprognostic (1.18e-2)" "prognostic favorable (6.82e-4)" NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149750-45160815 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Basal prostatic cells: 1.5;Horizontal cells: 2.6;Spermatocytes: 2.0;Suprabasal keratinocytes: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA043339 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" NKX1-2 "bB238F13.2, C10orf121" ENSG00000229544 "NK1 homeobox 2" Q9UD57 10 124445243-124450035 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Basal respiratory cells: 2.2" "Cancer enhanced" "Detected in some" "testis cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 12.8;testis cancer: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029367 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 46: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Nucleoli fibrillar center" "HPA029367: AB_2673011" "unprognostic (2.43e-1)" "unprognostic (7.85e-3)" "unprognostic (6.81e-5)" "unprognostic (1.55e-2)" "unprognostic (3.61e-2)" "unprognostic (5.40e-2)" "unprognostic (7.28e-2)" "unprognostic (2.20e-1)" "unprognostic (3.73e-2)" "unprognostic (2.69e-1)" "unprognostic (1.71e-1)" "unprognostic (8.68e-2)" NKX2-3 "CSX3, NKX2.3, NKX2C, NKX4-3" ENSG00000119919 "NK2 homeobox 3" Q8TAU0 10 99532942-99536524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 38.9;lymphoid tissue: 31.4;salivary gland: 15.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.2;Mucus glandular cells: 4.9;Salivary duct cells: 18.1;Serous glandular cells: 2.3;Suprabasal keratinocytes: 2.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047561 Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoli, Cytosol" "HPA047561: AB_2680088" "unprognostic (5.70e-2)" "unprognostic (2.95e-1)" "unprognostic (2.70e-4)" "unprognostic (6.34e-3)" "unprognostic (3.92e-2)" "unprognostic (7.40e-2)" "unprognostic (1.20e-1)" "unprognostic (4.91e-2)" "unprognostic (1.12e-1)" "unprognostic (1.19e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" NKX2-8 "Nkx2-9, NKX2.8, NKX2H" ENSG00000136327 "NK2 homeobox 8" O15522 14 36580004-36582614 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;esophagus: 2.6;testis: 7.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.6;Basal squamous epithelial cells: 7.2;Oligodendrocytes: 2.4;Sertoli cells: 11.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 9.1;head and neck cancer: 7.9" "Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062879 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Plasma membrane" "HPA062879: AB_2684892" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (2.27e-1)" "unprognostic (3.45e-4)" "unprognostic (2.36e-1)" "unprognostic (8.34e-2)" "unprognostic (7.80e-2)" "unprognostic (3.66e-1)" "unprognostic (3.11e-1)" "unprognostic (8.39e-3)" "unprognostic (4.60e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.7;Basal squamous epithelial cells: 48.8;Squamous epithelial cells: 241.2;Suprabasal keratinocytes: 242.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cancer enhanced" "Detected in all" "cervical cancer: 193.8" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" NOL6 "bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22" ENSG00000165271 "Nucleolar protein 6" Q9H6R4 9 33461353-33473930 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055891, HPA061002" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "HPA055891: AB_2682959, HPA061002: AB_2684410" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (2.37e-1)" "unprognostic (5.23e-2)" "unprognostic (2.32e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (4.83e-5)" "unprognostic (7.37e-3)" "unprognostic (8.26e-2)" "unprognostic (3.03e-2)" "unprognostic (2.09e-1)" "unprognostic (4.24e-2)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (4.09e-1)" NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 522.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 534.8;Respiratory ciliated cells: 377.9;Suprabasal keratinocytes: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Supported Cytosol NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" NRARP MGC61598 ENSG00000198435 "NOTCH regulated ankyrin repeat protein" Q7Z6K4 9 137299631-137302271 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 47.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 248.4;Schwann cells: 364.5;Squamous epithelial cells: 190.4;Suprabasal keratinocytes: 451.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 49.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025729 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA025729: AB_1854633" "unprognostic (9.92e-2)" "unprognostic (1.75e-2)" "unprognostic (1.56e-1)" "unprognostic (7.17e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (3.42e-2)" "unprognostic (1.89e-2)" "unprognostic (1.00e-2)" "unprognostic (6.42e-2)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.73e-6)" "unprognostic (2.85e-3)" "unprognostic (1.34e-1)" "unprognostic (4.90e-2)" "unprognostic (3.28e-3)" NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 192.6;Cytotrophoblasts: 120.3;Granulosa cells: 124.0;Melanocytes: 426.7;Suprabasal keratinocytes: 146.3;Theca cells: 129.9" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 61.4;skin cancer: 66.8" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 105.0;Basal keratinocytes: 70.1;Inhibitory neurons: 49.7;Late spermatids: 48.8;Muller glia cells: 86.8;Oligodendrocyte precursor cells: 119.4;Suprabasal keratinocytes: 64.7" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cancer enhanced" "Detected in many" "Bone cancer: 45.6" "Breast - Adipocytes (Breast), Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Supported Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" OVOL1 HOVO1 ENSG00000172818 "Ovo like transcriptional repressor 1" O14753 11 65787063-65797214 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 57.2;skin 1: 51.0;testis: 35.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 110.5;Late spermatids: 92.3;Squamous epithelial cells: 134.2;Suprabasal keratinocytes: 95.5;Syncytiotrophoblasts: 306.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003984 Uncertain Approved Nucleoplasm Yes NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA003984: AB_1854854" "unprognostic (4.26e-3)" "unprognostic (3.39e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (3.37e-1)" "unprognostic (1.26e-2)" "unprognostic (1.95e-1)" "unprognostic (2.31e-2)" "unprognostic (2.01e-3)" "unprognostic (1.91e-1)" "prognostic favorable (1.00e-13)" "unprognostic (4.26e-2)" "unprognostic (3.51e-2)" "unprognostic (2.42e-1)" "unprognostic (9.04e-3)" PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.7;Extravillous trophoblasts: 36.4;Suprabasal keratinocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA016930: AB_1854954" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.09e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-3)" PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 81.0;lymphoid tissue: 20.5;parathyroid gland: 43.0;salivary gland: 51.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 37.3;Basal respiratory cells: 43.7;Basal squamous epithelial cells: 166.4;Serous glandular cells: 92.1;Squamous epithelial cells: 163.6;Suprabasal keratinocytes: 64.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "CAB016239: AB_2159984, HPA001572: " "unprognostic (3.09e-1)" "prognostic favorable (5.38e-4)" "unprognostic (1.56e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-2)" "unprognostic (5.93e-3)" "unprognostic (2.71e-3)" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (2.41e-2)" "unprognostic (9.44e-2)" "unprognostic (2.31e-4)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3404.2;Squamous epithelial cells: 3820.8;Suprabasal keratinocytes: 7537.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "Kupffer cells: 243.8;Squamous epithelial cells: 580.7;Suprabasal keratinocytes: 340.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Heart muscle - Macrophages, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Group enriched" "Detected in some" 4 "granulocytes: 1.6;Squamous epithelial cells: 6.0;Suprabasal keratinocytes: 2.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 8.1" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" PHF13 MGC43399 ENSG00000116273 "PHD finger protein 13" Q86YI8 1 6613731-6624030 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026830 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA026830: AB_1855288" "unprognostic (6.59e-3)" "unprognostic (7.71e-2)" "unprognostic (2.62e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (9.84e-3)" "unprognostic (2.62e-1)" "unprognostic (1.59e-1)" "unprognostic (8.73e-3)" "unprognostic (1.40e-2)" "unprognostic (1.68e-3)" "unprognostic (1.58e-1)" "unprognostic (3.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.05e-1)" PHF23 "FLJ16355, MGC2941" ENSG00000040633 "PHD finger protein 23" Q9BUL5 17 7235029-7239722 "Disease related genes, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052410 Approved Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 49: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA052410: AB_2681822" "unprognostic (1.76e-2)" "unprognostic (6.12e-2)" "unprognostic (4.72e-2)" "unprognostic (6.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.96e-2)" "unprognostic (2.41e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.19e-1)" "unprognostic (2.67e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (4.40e-1)" "unprognostic (1.61e-1)" "unprognostic (3.48e-2)" PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 405.4;Basal squamous epithelial cells: 515.4;Serous glandular cells: 276.8;Squamous epithelial cells: 1186.7;Suprabasal keratinocytes: 1131.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 152.7" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 315.6;Squamous epithelial cells: 258.3;Suprabasal keratinocytes: 748.6" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 171.3;head and neck cancer: 98.1" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 19.7;Suprabasal keratinocytes: 39.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" PLEKHA1 TAPP1 ENSG00000107679 "Pleckstrin homology domain containing A1" Q9HB21 10 122374696-122442602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 10.3;NK-cells: 21.3;T-cells: 27.1" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002043, HPA064795" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA002043: AB_1079632, HPA064795: AB_2685354" "unprognostic (1.79e-2)" "unprognostic (3.18e-2)" "unprognostic (2.70e-1)" "unprognostic (5.44e-3)" "unprognostic (7.41e-2)" "unprognostic (1.69e-1)" "unprognostic (5.50e-2)" "unprognostic (4.07e-2)" "unprognostic (3.88e-1)" "unprognostic (2.69e-1)" "unprognostic (7.98e-2)" "unprognostic (7.63e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (7.42e-2)" "unprognostic (4.31e-2)" "unprognostic (5.23e-2)" PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.2;Suprabasal keratinocytes: 15.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 56: Neurons - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" PLEKHH3 FLJ21019 ENSG00000068137 "Pleckstrin homology, MyTH4 and FERM domain containing H3" Q7Z736 17 42667914-42676994 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 41.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046234 Uncertain Approved "Golgi apparatus" NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" "HPA046234: AB_2679597" "unprognostic (1.32e-1)" "unprognostic (2.56e-1)" "unprognostic (2.75e-2)" "unprognostic (5.72e-3)" "unprognostic (1.25e-1)" "unprognostic (3.42e-3)" "unprognostic (5.05e-3)" "unprognostic (5.95e-2)" "unprognostic (6.45e-2)" "unprognostic (1.63e-2)" "unprognostic (1.51e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.87e-1)" "unprognostic (1.72e-1)" "unprognostic (9.30e-3)" "unprognostic (1.44e-3)" POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.9;Suprabasal keratinocytes: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Non-specific - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: AB_10795693, HPA041734: AB_10794489" "unprognostic (1.03e-1)" "unprognostic (8.98e-2)" "unprognostic (9.28e-2)" "unprognostic (1.37e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (4.79e-9)" "unprognostic (1.62e-3)" "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-9)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-2)" "unprognostic (4.53e-2)" PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 168.0;Cardiomyocytes: 95.4;Respiratory ciliated cells: 62.3;Skeletal myocytes: 120.7;Suprabasal keratinocytes: 187.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 36.2" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 122.4;Basal squamous epithelial cells: 127.9;Squamous epithelial cells: 148.1;Suprabasal keratinocytes: 189.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.1;Astrocytes: 160.1;Cone photoreceptor cells: 137.9;Oligodendrocytes: 189.0;Rod photoreceptor cells: 166.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 47: Retina - Visual perception" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" PYDC1 "ASC2, POP1" ENSG00000169900 "Pyrin domain containing 1" Q8WXC3 16 31215962-31217135 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 8.1;skin 1: 14.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.1;Breast myoepithelial cells: 1.7;Langerhans cells: 1.4;Skeletal myocytes: 2.0;Suprabasal keratinocytes: 3.1" "Cancer enriched" "Detected in some" 8 "breast cancer: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (9.72e-3)" "unprognostic (1.00e-2)" "unprognostic (2.05e-2)" "unprognostic (1.61e-1)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.62e-1)" "unprognostic (5.34e-2)" "unprognostic (3.15e-2)" "unprognostic (2.60e-10)" "unprognostic (3.62e-1)" "unprognostic (1.74e-1)" "unprognostic (1.70e-1)" "unprognostic (9.47e-2)" RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.6;skin 1: 44.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.9;Basal respiratory cells: 69.0;Cytotrophoblasts: 95.4;Melanocytes: 191.6;Suprabasal keratinocytes: 113.8" "Cancer enhanced" "Detected in all" "melanoma: 73.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 85.9;skin cancer: 97.9" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.1" HPA071701 Uncertain "Nuclear bodies,Mitochondria" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear bodies, Mitochondria" "HPA071701: " "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (2.66e-2)" "unprognostic (1.36e-2)" "unprognostic (7.95e-2)" "unprognostic (3.96e-4)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "unprognostic (9.34e-2)" "unprognostic (1.00e-2)" "unprognostic (8.23e-2)" "prognostic favorable (8.26e-4)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" RAP2B ENSG00000181467 "RAP2B, member of RAS oncogene family" P61225 3 153162226-153170627 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 280.4;Squamous epithelial cells: 258.0;Suprabasal keratinocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (2.44e-2)" "unprognostic (2.19e-1)" "unprognostic (2.13e-1)" "unprognostic (3.51e-2)" "unprognostic (3.04e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (2.00e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (5.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.32e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-2)" RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 65.1;Distal enterocytes: 80.1;Squamous epithelial cells: 102.3;Suprabasal keratinocytes: 122.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Kidney - Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 41.8;Basal squamous epithelial cells: 46.1;Squamous epithelial cells: 74.1;Suprabasal keratinocytes: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" RASSF10 ENSG00000189431 "Ras association domain family member 10" A6NK89 11 13009316-13012119 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.0;skin 1: 6.6" "Group enriched" "Detected in many" 4 "Basal squamous epithelial cells: 142.7;Squamous epithelial cells: 115.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.3" "Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040406 Approved Vesicles,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA040406: AB_2732485" "unprognostic (6.71e-2)" "unprognostic (5.12e-2)" "unprognostic (5.06e-2)" "unprognostic (2.41e-3)" "unprognostic (6.25e-3)" "prognostic favorable (2.76e-4)" "unprognostic (3.43e-3)" "unprognostic (8.04e-2)" "unprognostic (5.89e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (4.12e-5)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.8;skin 1: 129.8;vagina: 92.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 143.8;Club cells: 180.4;Paneth cells: 199.2;Squamous epithelial cells: 406.4;Suprabasal keratinocytes: 331.7" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053343 Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.3;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 25.1;monocytes: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" RND3 "ARHE, Rho8, RhoE" ENSG00000115963 "Rho family GTPase 3" P61587 2 150468195-150539011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 155.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1222.9;Endometrial stromal cells: 482.3;Squamous epithelial cells: 460.2;Suprabasal keratinocytes: 773.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060504 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA060504: AB_2684295" "unprognostic (8.03e-2)" "unprognostic (3.04e-2)" "unprognostic (2.36e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-3)" "unprognostic (4.23e-2)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (2.03e-2)" RNF227 LINC02581 ENSG00000179859 "Ring finger protein 227" A6NIN4 17 7913339-7916289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "skin 1: 64.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 28.0;Basal squamous epithelial cells: 17.2;Suprabasal keratinocytes: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 17.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 17.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.85e-3)" "prognostic favorable (8.89e-5)" "unprognostic (1.50e-2)" "unprognostic (4.88e-2)" "unprognostic (3.72e-3)" "unprognostic (1.44e-2)" "unprognostic (2.02e-5)" "unprognostic (9.48e-2)" "unprognostic (9.22e-3)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.30e-2)" "unprognostic (1.80e-2)" RTL8A "CXX1b, DKFZP564B147, FAM127B, MAR8A, SIRH6" ENSG00000203950 "Retrotransposon Gag like 8A" Q9BWD3 X 135050932-135052196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 48: Non-specific - RNA binding" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (2.10e-2)" "prognostic favorable (5.35e-4)" "unprognostic (2.07e-3)" "prognostic unfavorable (2.83e-4)" "unprognostic (9.91e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (1.10e-5)" "unprognostic (2.16e-2)" "unprognostic (4.48e-1)" "prognostic favorable (2.71e-4)" "unprognostic (2.05e-2)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-1)" "unprognostic (2.51e-1)" "unprognostic (3.35e-2)" "unprognostic (1.57e-2)" S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9637.5;Basal respiratory cells: 9321.8;Basal squamous epithelial cells: 5696.3;Squamous epithelial cells: 9526.1;Suprabasal keratinocytes: 4651.4" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 7485.7;head and neck cancer: 2572.9" "Breast - Breast myoepithelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1065.7;lymphoid tissue: 1239.6;skin 1: 346.5;vagina: 1020.1" "Group enriched" "Detected in some" 9 "Basal keratinocytes: 2332.1;granulocytes: 734.9;Serous glandular cells: 2161.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "cervical cancer: 141.2;head and neck cancer: 554.2" "CAB001453, HPA006997, CAB033766" Enhanced Supported Cytosol "Secreted in other tissues" NA NA 14000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" S100A7A "S100A15, S100A7f, S100A7L1" ENSG00000184330 "S100 calcium binding protein A7A" Q86SG5 1 153416520-153423222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.6;lymphoid tissue: 5.9;skin 1: 1.6;vagina: 2.7" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 5.3;Late spermatids: 4.3;Serous glandular cells: 2.2" "Group enriched" "Detected in many" 4 "head and neck cancer: 25.6;melanoma: 12.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 7.5" "Testis - Late spermatids" HPA006997 Supported Uncertain Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA006997: AB_1079860" "unprognostic (2.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (4.40e-3)" SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" SERPINA12 "OL-64, Vaspin" ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 396.4" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 11.0" "Group enriched" "Detected in some" 5 "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 6500000 "Cluster 61: Skin - Cornification" "Cluster 35: Liver cancer - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" SERPINB12 YUKOPIN ENSG00000166634 "Serpin family B member 12" Q96P63 18 63542369-63569329 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 13.9;skin 1: 59.1;vagina: 25.6" "Group enriched" "Detected in some" 8 "Suprabasal keratinocytes: 3.8;Syncytiotrophoblasts: 2.3" "Group enriched" "Detected in some" 14 "cervical cancer: 7.3;head and neck cancer: 2.1;lung cancer: 1.9;melanoma: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "lung cancer: 3.1;Rhabdoid: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 8200000 "Cluster 31: Skin - Epidermis development" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (7.35e-2)" "prognostic favorable (1.76e-4)" "unprognostic (1.57e-1)" "unprognostic (2.00e-1)" "unprognostic (8.10e-2)" SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Group enriched" "Detected in many" 8 "Basal keratinocytes: 1551.5;Suprabasal keratinocytes: 672.5;Syncytiotrophoblasts: 692.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 317.0" "Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 720.3;Basal respiratory cells: 245.5;Basal squamous epithelial cells: 359.0;Squamous epithelial cells: 538.3;Suprabasal keratinocytes: 811.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 136.6" "Breast - Breast myoepithelial cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" SERTAD2 "KIAA0127, Sei-2, TRIP-Br2" ENSG00000179833 "SERTA domain containing 2" Q14140 2 64631621-64751005 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 85.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 140.3;Basal squamous epithelial cells: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019021, HPA020904" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Cytosol "HPA019021: AB_1856740, HPA020904: AB_1856741" "unprognostic (1.40e-2)" "unprognostic (7.41e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.15e-2)" "unprognostic (8.15e-2)" "unprognostic (3.39e-3)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (5.95e-3)" "unprognostic (1.98e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.21e-3)" "unprognostic (6.78e-2)" "unprognostic (4.98e-2)" "unprognostic (3.84e-1)" SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7116.0;Basal squamous epithelial cells: 1998.6;Squamous epithelial cells: 3827.5;Suprabasal keratinocytes: 12306.6" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1300.7;head and neck cancer: 885.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427131 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 88.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9.8;Collecting duct cells: 11.8;Glandular and luminal cells: 8.6;Suprabasal keratinocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 29.3" "Low region specificity" "Detected in all" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Enzymes" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm Vesicles "CAB023801: , HPA038211: AB_2675894, HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 31.1;kidney: 61.3" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 86.2;Squamous epithelial cells: 60.4" "Cancer enhanced" "Detected in many" "prostate cancer: 11.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 38.8" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.2" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 7: Kidney - Transmembrane transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA029295: AB_10610425" "unprognostic (1.17e-3)" "unprognostic (6.46e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (8.62e-2)" "unprognostic (1.43e-2)" "unprognostic (8.30e-2)" "unprognostic (5.46e-3)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-3)" "unprognostic (9.18e-2)" "unprognostic (9.18e-7)" "unprognostic (2.98e-2)" "unprognostic (3.79e-2)" "unprognostic (1.07e-2)" "prognostic favorable (2.88e-4)" SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 846.8;Suprabasal keratinocytes: 712.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" SLC7A1 "ATRC1, CAT-1, ERR, HCAT1, REC1L" ENSG00000139514 "Solute carrier family 7 member 1" P30825 13 29509414-29595688 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 229.6;Microglial cells: 157.8;Squamous epithelial cells: 156.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039721, HPA077838" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA039721: AB_10672893, HPA077838: " "unprognostic (1.85e-1)" "unprognostic (1.04e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (1.36e-3)" "unprognostic (2.02e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.20e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (7.37e-3)" SOWAHC "ANKRD57, C2orf26, FLJ21870" ENSG00000198142 "Sosondowah ankyrin repeat domain family member C" Q53LP3 2 109614364-109618990 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 145.4;Granulosa cells: 150.1;Squamous epithelial cells: 140.2;Suprabasal keratinocytes: 178.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA056131 Enhanced Approved Cytosol No No "Cluster 37: Intestine - Unknown function" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "HPA056131: AB_2683047" "unprognostic (6.76e-2)" "unprognostic (6.96e-2)" "unprognostic (9.61e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.87e-1)" "unprognostic (8.91e-3)" "unprognostic (1.63e-2)" "unprognostic (1.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (5.11e-3)" "prognostic favorable (3.56e-5)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (3.50e-1)" "unprognostic (2.54e-2)" SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 180.4;Basal squamous epithelial cells: 425.3;Squamous epithelial cells: 364.3;Suprabasal keratinocytes: 166.4" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Cancer enhanced" "Detected in all" "Esophageal cancer: 49.7;head and neck cancer: 73.9" "Skin - Keratinocyte (other), Thyroid - Fibroblasts" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" SOX21 SOX25 ENSG00000125285 "SRY-box transcription factor 21" Q9Y651 13 94709622-94712545 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.8;esophagus: 10.3;skin 1: 15.9;stomach 1: 35.1" "Cell type enhanced" "Detected in some" "Astrocytes: 23.7;Basal squamous epithelial cells: 21.3;Gastric mucus-secreting cells: 62.0;Oligodendrocyte precursor cells: 16.4;Squamous epithelial cells: 62.3" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.4" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048337, HPA064084" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA048337: AB_2732547, HPA064084: AB_2685187" "unprognostic (3.33e-1)" "prognostic favorable (7.60e-4)" "unprognostic (7.96e-2)" "prognostic favorable (8.79e-5)" "unprognostic (1.54e-2)" "unprognostic (3.87e-1)" "unprognostic (9.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (1.93e-1)" "unprognostic (6.05e-2)" "unprognostic (1.11e-1)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 204.9;Cholangiocytes: 192.5;Mucus glandular cells: 172.8;Salivary duct cells: 213.8;Sertoli cells: 171.4;Squamous epithelial cells: 278.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Prostate - Prostate basal glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240, HPA070776" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 56: Neurons - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067, HPA070776: " "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 181.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 22: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" SPRR2B ENSG00000196805 "Small proline rich protein 2B" P35325 1 153070224-153070840 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 50.1;skin 1: 39.0" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 61.8;granulocytes: 31.0;Serous glandular cells: 105.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 77.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.52e-1)" "unprognostic (1.44e-2)" "unprognostic (3.62e-1)" SPRR2D ENSG00000163216 "Small proline rich protein 2D" P22532 1 153039732-153041931 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 2086.0" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 503.4;granulocytes: 150.2;Serous glandular cells: 525.4;Suprabasal keratinocytes: 480.8" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 353.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 71.0;skin cancer: 35.4" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (7.50e-2)" "unprognostic (1.84e-1)" "unprognostic (5.17e-2)" "unprognostic (5.14e-2)" "unprognostic (1.49e-3)" "unprognostic (3.58e-1)" "unprognostic (1.37e-3)" "unprognostic (6.85e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.62e-4)" SPRR2E ENSG00000203785 "Small proline rich protein 2E" P22531 1 153093135-153106184 "Predicted intracellular proteins" Keratinization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 1773.2;skin 1: 1179.2" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 1622.4;granulocytes: 527.5;Serous glandular cells: 1790.8;Suprabasal keratinocytes: 548.7" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 612.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Esophageal cancer: 9.4;head and neck cancer: 21.3;pancreatic cancer: 6.3" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (2.27e-1)" "unprognostic (3.86e-2)" "unprognostic (5.04e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (9.47e-4)" SPRR2G ENSG00000159516 "Small proline rich protein 2G" Q9BYE4 1 153149582-153150890 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "skin 1: 969.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 54.7;Extravillous trophoblasts: 19.6;Serous glandular cells: 96.1;Suprabasal keratinocytes: 82.3" "Group enriched" "Detected in many" 15 "head and neck cancer: 256.0;melanoma: 131.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 8.9" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (3.93e-1)" "unprognostic (1.90e-1)" "unprognostic (3.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.69e-2)" SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 99.7;Hepatocytes: 97.9;Squamous epithelial cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 26.9;Late spermatids: 13.0;Schwann cells: 11.6;Squamous epithelial cells: 17.4" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.0" "Cancer enhanced" "Detected in many" "cervical cancer: 33.5;head and neck cancer: 35.9" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.2;Plasma cells: 33.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.4;Inhibitory neurons: 87.7;Oligodendrocyte precursor cells: 97.2;Squamous epithelial cells: 79.5;Suprabasal keratinocytes: 50.0;Theca cells: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cancer enhanced" "Detected in many" "breast cancer: 16.5" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 159.5;NK-cells: 150.6;Squamous epithelial cells: 181.7;Suprabasal keratinocytes: 151.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 62.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Skin - Keratinocyte (other), Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" TENT5B "FAM46B, MGC16491" ENSG00000158246 "Terminal nucleotidyltransferase 5B" Q96A09 1 27005020-27012850 "Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 111.8;skin 1: 121.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 70.8;Basal keratinocytes: 107.2;Basal squamous epithelial cells: 83.1;Squamous epithelial cells: 158.7;Suprabasal keratinocytes: 215.2" "Cancer enhanced" "Detected in many" "testis cancer: 87.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.67e-2)" "unprognostic (5.94e-3)" "unprognostic (1.61e-1)" "unprognostic (5.28e-3)" "unprognostic (3.20e-2)" "unprognostic (2.22e-2)" "unprognostic (2.44e-4)" "unprognostic (4.05e-2)" "unprognostic (1.39e-1)" "unprognostic (6.02e-3)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 96.0;Basal squamous epithelial cells: 106.2;Breast glandular cells: 58.0;Breast myoepithelial cells: 64.1;Cytotrophoblasts: 89.6;Extravillous trophoblasts: 59.0;Squamous epithelial cells: 71.2;Suprabasal keratinocytes: 93.4;Syncytiotrophoblasts: 109.0" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 70.8" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 325.4;Microglial cells: 240.8;Squamous epithelial cells: 111.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Hepatocytes: 78.4;Suprabasal keratinocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 59000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 62: Granulocytes - Innate immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Mitochondria "HPA003628: AB_1080284" "prognostic unfavorable (7.89e-5)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (8.87e-5)" "unprognostic (2.06e-1)" "unprognostic (9.28e-3)" "unprognostic (5.14e-3)" "unprognostic (8.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-3)" "unprognostic (6.41e-2)" "unprognostic (8.57e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (1.70e-1)" "unprognostic (3.86e-2)" TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 71.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.5;Suprabasal keratinocytes: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 49: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (5.64e-2)" "prognostic favorable (3.53e-6)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (1.32e-3)" "unprognostic (2.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (4.88e-2)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-2)" TLX1 "HOX11, TCL3" ENSG00000107807 "T cell leukemia homeobox 1" P31314 10 101131300-101137789 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "lymphoid tissue: 43.9;salivary gland: 16.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.4;Mucus glandular cells: 4.1;Salivary duct cells: 7.7;Suprabasal keratinocytes: 1.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.06e-5)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (5.07e-1)" "unprognostic (1.57e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.81e-1)" "unprognostic (2.63e-1)" "unprognostic (3.26e-1)" "unprognostic (3.06e-1)" "unprognostic (7.35e-2)" TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 258.0" "Cell type enhanced" "Detected in all" "Late spermatids: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 100.9;Basal squamous epithelial cells: 141.1;Squamous epithelial cells: 125.6;Suprabasal keratinocytes: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 192.4;Squamous epithelial cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 43: Non-specific - Mitochondria" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 51.4;Microglial cells: 69.3;Prostatic glandular cells: 50.3;Respiratory ciliated cells: 40.0;Suprabasal keratinocytes: 53.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 52.9;skin cancer: 49.2" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved "Nucleoplasm,Golgi apparatus" No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus" Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" TNK1 KOS1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.1;Distal enterocytes: 13.8;Gastric mucus-secreting cells: 11.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.9" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favorable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.52e-4)" TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" TNS4 CTEN ENSG00000131746 "Tensin 4" Q8IZW8 17 40475828-40501623 "Predicted intracellular proteins" Apoptosis Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 205.0;vagina: 74.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.8;Basal prostatic cells: 111.5;Basal squamous epithelial cells: 199.6;Mucus glandular cells: 45.9;Salivary duct cells: 103.3;Squamous epithelial cells: 55.5;Suprabasal keratinocytes: 46.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 77.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 75.9" "Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (4.16e-2)" "unprognostic (9.83e-2)" "unprognostic (1.01e-1)" "unprognostic (3.40e-2)" "unprognostic (3.68e-4)" "unprognostic (7.88e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.89e-1)" "unprognostic (8.02e-3)" "unprognostic (2.01e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (3.72e-1)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (7.08e-2)" TOR1AIP2 "IFRG15, LULL1, NET9" ENSG00000169905 "Torsin 1A interacting protein 2" "Q8NFQ8, Q9H496" 1 179839967-179877803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051849, HPA058348, HPA070542" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: Non-specific - RNA binding" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA051849: AB_2681637, HPA058348: AB_2683687, HPA070542: AB_2686278" "unprognostic (1.22e-1)" "unprognostic (8.49e-3)" "unprognostic (2.61e-1)" "unprognostic (2.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.82e-1)" "unprognostic (6.17e-2)" "unprognostic (7.64e-3)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.99e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (1.36e-1)" TP53AIP1 p53AIP1 ENSG00000120471 "Tumor protein p53 regulated apoptosis inducing protein 1" Q9HCN2 11 128934731-128943399 "Predicted intracellular proteins" Apoptosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;lymphoid tissue: 29.5;skin 1: 20.4;vagina: 13.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.1;Basal respiratory cells: 40.9;Basal squamous epithelial cells: 144.5;Breast myoepithelial cells: 28.3;Endometrial ciliated cells: 38.1;Squamous epithelial cells: 55.0;Suprabasal keratinocytes: 33.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 2.7" "Lung - Respiratory ciliated cells" "HPA044300, HPA048797" Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA044300: AB_2678888, HPA048797: AB_2680524" "unprognostic (4.12e-7)" "unprognostic (3.00e-2)" "unprognostic (1.48e-1)" "unprognostic (1.64e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-2)" "unprognostic (1.18e-1)" "unprognostic (4.66e-2)" "unprognostic (1.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.94e-1)" "unprognostic (6.57e-6)" "unprognostic (1.10e-2)" "unprognostic (3.71e-1)" "unprognostic (7.75e-2)" "unprognostic (1.78e-2)" TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Basal squamous epithelial cells: 251.1;Skeletal myocytes: 81.2;Squamous epithelial cells: 157.7;Suprabasal keratinocytes: 189.8" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 110.8;Gallbladder cancer: 189.5;head and neck cancer: 118.7" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" TRIM26 "RNF95, ZNF173" ENSG00000234127 "Tripartite motif containing 26" Q12899 6 30184455-30213427 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044975, HPA050456" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein binding" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA044975: AB_2679162, HPA050456: AB_2681133" "unprognostic (1.93e-1)" "unprognostic (5.41e-2)" "unprognostic (8.53e-2)" "unprognostic (1.96e-3)" "unprognostic (1.52e-1)" "unprognostic (5.50e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-2)" "unprognostic (2.85e-1)" "unprognostic (3.08e-2)" "unprognostic (1.97e-1)" "unprognostic (7.00e-3)" "unprognostic (1.37e-2)" "unprognostic (1.63e-3)" "unprognostic (5.21e-2)" "unprognostic (8.82e-2)" "prognostic favorable (3.25e-5)" TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 446.6;Basal squamous epithelial cells: 306.0;Squamous epithelial cells: 583.8;Suprabasal keratinocytes: 899.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 225.9;Gallbladder cancer: 151.3;head and neck cancer: 166.8" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.5;urinary bladder: 12.0" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 103.5;Basal squamous epithelial cells: 213.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 38400 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" UBALD1 FAM100A ENSG00000153443 "UBA like domain containing 1" Q8TB05 16 4608883-4615027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 116.1;Syncytiotrophoblasts: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066771 Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: Non-specific - Transcription" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA066771: AB_2685717" "unprognostic (7.09e-2)" "unprognostic (2.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.67e-3)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" "unprognostic (4.37e-3)" "unprognostic (2.63e-3)" "unprognostic (8.06e-2)" "unprognostic (1.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.99e-2)" "unprognostic (6.20e-2)" "unprognostic (1.35e-2)" UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 210.2" "Cell type enhanced" "Detected in all" "Late spermatids: 261.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 49: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.5;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "skin cancer: 137.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 33: Skin cancer - Membrane components" "Cluster 22: Squamous epithelial cells - Keratinization" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Group enriched" "Detected in some" 7 "Basal squamous epithelial cells: 11.2;Squamous epithelial cells: 44.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "cervical cancer: 37.5" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" VGLL4 KIAA0121 ENSG00000144560 "Vestigial like family member 4" Q14135 3 11556069-11771350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038225, HPA038614" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA No "Cluster 18: Basophils - Vesicular transport" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" Nucleoplasm "HPA038225: AB_10674549, HPA038614: AB_2676115" "unprognostic (1.21e-2)" "unprognostic (4.68e-3)" "unprognostic (3.29e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-1)" "unprognostic (6.13e-2)" "unprognostic (1.24e-2)" "unprognostic (2.73e-1)" "unprognostic (1.66e-1)" "unprognostic (4.35e-3)" "unprognostic (2.01e-2)" "unprognostic (1.86e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.04e-1)" "unprognostic (8.81e-2)" "unprognostic (9.42e-2)" "unprognostic (1.26e-1)" VMP1 "EPG3, TANGO5, TMEM49" ENSG00000062716 "Vacuole membrane protein 1" Q96GC9 17 59707192-59842255 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Cell adhesion, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 3000.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 3000.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030773, HPA064780" Approved Approved "Nucleoli,Endoplasmic reticulum" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" Nucleoli "HPA030773: AB_10602248, HPA064780: AB_2685348" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.39e-1)" "unprognostic (2.41e-1)" "unprognostic (2.98e-1)" "unprognostic (8.43e-2)" "unprognostic (4.21e-2)" "prognostic unfavorable (2.77e-8)" "unprognostic (1.88e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-3)" VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946056-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "skin 1: 18.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.7;Breast glandular cells: 11.4;Breast myoepithelial cells: 6.1;Club cells: 4.5;Ionocytes: 6.4;Suprabasal keratinocytes: 20.2" "Region enhanced" "Detected in single" "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 93.1;Suprabasal keratinocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 38: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115172 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 393.9" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 39.4;Early spermatids: 10.6;Late spermatids: 15.1;Suprabasal keratinocytes: 33.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 2.5;head and neck cancer: 5.4" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" ZBTB5 KIAA0354 ENSG00000168795 "Zinc finger and BTB domain containing 5" O15062 9 37438102-37465450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021521 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 55: Non-specific - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA021521: AB_2670736" "unprognostic (2.36e-2)" "unprognostic (2.78e-2)" "unprognostic (5.22e-2)" "unprognostic (6.35e-2)" "unprognostic (1.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.96e-3)" "unprognostic (5.81e-2)" "unprognostic (3.95e-2)" "unprognostic (1.43e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" "unprognostic (1.27e-3)" "unprognostic (5.73e-3)" "unprognostic (2.30e-1)" "unprognostic (2.77e-3)" "unprognostic (1.80e-1)" ZBTB7A "DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A" ENSG00000178951 "Zinc finger and BTB domain containing 7A" O95365 19 4043303-4066899 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037214, CAB037285, HPA046387" Supported Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 47: Non-specific - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB037214: AB_609875, CAB037285: AB_609874, HPA046387: AB_2679648" "unprognostic (8.88e-2)" "unprognostic (1.21e-1)" "unprognostic (3.02e-1)" "prognostic favorable (6.50e-6)" "unprognostic (7.54e-2)" "unprognostic (3.65e-3)" "unprognostic (3.71e-2)" "unprognostic (1.12e-1)" "unprognostic (1.56e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.75e-1)" "prognostic favorable (1.34e-6)" "prognostic favorable (1.79e-4)" "unprognostic (2.01e-1)" "unprognostic (4.25e-1)" "unprognostic (1.36e-2)" ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 69.4;Oligodendrocyte precursor cells: 49.1;Squamous epithelial cells: 99.6;Suprabasal keratinocytes: 67.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 22 "cervical cancer: 156.5" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.83e-3)" "unprognostic (6.60e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (3.85e-3)" "unprognostic (2.89e-2)" ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 2061.3;Squamous epithelial cells: 1882.1;Suprabasal keratinocytes: 2216.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2901.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2901.2" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA055357: AB_2682793" "unprognostic (4.36e-3)" "unprognostic (6.73e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (8.73e-3)" "unprognostic (5.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (6.00e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.76e-2)" ZNF436 "KIAA1710, Zfp46" ENSG00000125945 "Zinc finger protein 436" Q9C0F3 1 23359448-23369836 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 20.6;Squamous epithelial cells: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043817 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA043817: AB_10794774" "unprognostic (1.50e-1)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (1.93e-1)" "unprognostic (8.10e-2)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.86e-1)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.92e-1)" "unprognostic (9.51e-3)" "unprognostic (5.04e-2)" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (7.75e-3)" ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 232.3;Schwann cells: 136.7;Squamous epithelial cells: 166.8" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 2: DU4475 - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 101.2;Basal squamous epithelial cells: 56.2;Serous glandular cells: 49.7;Squamous epithelial cells: 159.8;Suprabasal keratinocytes: 198.8;Syncytiotrophoblasts: 69.0" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 15.1;head and neck cancer: 8.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" ZNF77 pT1 ENSG00000175691 "Zinc finger protein 77" Q15935 19 2933218-2944971 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023397 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 53: Non-specific - mRNA processing" "Cluster 22: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "HPA023397: AB_1859447" "unprognostic (1.17e-2)" "prognostic favorable (8.49e-4)" "unprognostic (2.18e-1)" "prognostic favorable (6.65e-5)" "unprognostic (2.01e-3)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-6)" "unprognostic (2.06e-1)" "unprognostic (5.03e-2)" "unprognostic (3.93e-3)" "unprognostic (2.65e-3)" "unprognostic (3.20e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.84e-2)" "unprognostic (1.79e-3)" ZXDB ZNF905 ENSG00000198455 "Zinc finger X-linked duplicated B" P98169 X 57592011-57597477 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 19.4;Suprabasal keratinocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA043789: AB_2678673" "unprognostic (1.87e-1)" "unprognostic (3.22e-1)" "unprognostic (1.88e-1)" "unprognostic (8.61e-3)" "unprognostic (4.29e-2)" "unprognostic (2.80e-1)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (4.36e-1)" "unprognostic (9.04e-2)" "unprognostic (6.73e-2)" "unprognostic (2.16e-2)" "unprognostic (1.17e-3)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (4.02e-3)" "unprognostic (2.87e-3)"