Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 556.3;vagina: 204.8" "Group enriched" "Detected in some" 5 "Squamous epithelial cells: 158.7;Suprabasal keratinocytes: 481.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 18.1" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 32.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Fibroblasts, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 88.1" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 16.2" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Prostate - Prostate glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Schwann cells: 1081.4;Suprabasal keratinocytes: 1089.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662160-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.6;Glandular and luminal cells: 27.4;Squamous epithelial cells: 64.1;Suprabasal keratinocytes: 47.7;Syncytiotrophoblasts: 18.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "breast cancer: 82.5" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 287.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 11.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3689.8;Suprabasal keratinocytes: 8448.8;Syncytiotrophoblasts: 8511.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085686-104115582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.4;liver: 151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.9;Distal enterocytes: 25.5;Granulosa cells: 65.4;Hepatocytes: 76.4;Proximal tubular cells: 45.5;Suprabasal keratinocytes: 64.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA069761 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA069761: AB_2686191" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 128.5;skin 1: 181.4;vagina: 69.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.1;Squamous epithelial cells: 50.0;Suprabasal keratinocytes: 84.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Not detected" "Not detected" HPA019946 Uncertain Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" BX255925.3 ENSG00000284976 "Novel RING finger protein" 9 137217452-137219361 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 36.7;Gastric mucus-secreting cells: 45.3;Proximal enterocytes: 40.9;Suprabasal keratinocytes: 43.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" C12orf29 DKFZp434N2030 ENSG00000133641 "Chromosome 12 open reading frame 29" Q8N999 12 88033846-88050160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039663 Uncertain Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "HPA039663: AB_10795253" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (7.80e-2)" "unprognostic (6.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.75e-3)" "unprognostic (4.72e-3)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (8.81e-2)" "unprognostic (6.49e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.29e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" C12orf56 ENSG00000185306 "Chromosome 12 open reading frame 56" Q8IXR9 12 64264762-64390758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 6.6;testis: 7.5" "Cell type enhanced" "Detected in some" "Early spermatids: 54.2;Late spermatids: 43.7;Oligodendrocytes: 12.8;Proximal tubular cells: 11.3;Spermatocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;thyroid cancer: 1.4" "Kidney - Podocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA056986 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA056986: AB_2683300" "unprognostic (5.85e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.36e-1)" "unprognostic (9.24e-2)" "unprognostic (9.35e-4)" "unprognostic (1.79e-4)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (9.51e-2)" "unprognostic (6.22e-3)" "unprognostic (4.00e-2)" "unprognostic (2.38e-4)" "unprognostic (8.86e-2)" "unprognostic (3.91e-2)" "unprognostic (3.40e-2)" "unprognostic (1.69e-2)" CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80209331 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;skin 1: 14.4;vagina: 7.3" "Cell type enhanced" "Detected in many" "Microglial cells: 6.4;Oligodendrocytes: 10.9;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 11.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Aggresome,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Aggresome "HPA023388: AB_1846020" "unprognostic (9.79e-3)" "unprognostic (3.86e-2)" "unprognostic (4.26e-1)" "unprognostic (1.05e-5)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.92e-4)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (3.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.62e-8)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 29.3" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 18.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.8;Suprabasal keratinocytes: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 55.1;skin 1: 64.0;vagina: 30.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 32.1;Basal squamous epithelial cells: 39.0;Early spermatids: 24.0;Late spermatids: 18.6;Spermatocytes: 24.4;Squamous epithelial cells: 49.9;Suprabasal keratinocytes: 87.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 11.9" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 124.7;Suprabasal keratinocytes: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" CLDN17 "MGC126552, MGC126554" ENSG00000156282 "Claudin 17" P56750 21 30165565-30166805 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 2.3;esophagus: 6.1;salivary gland: 6.4;vagina: 7.2" "Group enriched" "Detected in some" 4 "Early spermatids: 5.8;Suprabasal keratinocytes: 5.7" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045903 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA045903: AB_2679491" "unprognostic (2.41e-1)" CLIC3 ENSG00000169583 "Chloride intracellular channel 3" O95833 9 136994608-136996568 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 317.0;skin 1: 122.0;thyroid gland: 109.6;vagina: 132.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 791.2;Cytotrophoblasts: 791.8;dendritic cells: 754.6;Extravillous trophoblasts: 1449.1;NK-cells: 477.5;Suprabasal keratinocytes: 988.3;Syncytiotrophoblasts: 2221.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 130.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 9 "plasmacytoid DC: 2635.7" "Lineage enriched" "Detected in all" 9 "dendritic cells: 2635.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - NK-cells (Liver), Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005963 Enhanced Supported "Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies" "HPA005963: AB_1078536" "unprognostic (4.30e-2)" "unprognostic (2.53e-1)" "unprognostic (3.54e-1)" "unprognostic (1.55e-2)" "unprognostic (5.42e-3)" "unprognostic (1.85e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-3)" "unprognostic (1.39e-1)" "unprognostic (3.26e-3)" "unprognostic (7.73e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.74e-4)" CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 1649.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cancer enhanced" "Detected in all" "head and neck cancer: 22.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 579.1;esophagus: 1822.3;vagina: 867.6" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 1021.8" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 68.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 6.3;head and neck cancer: 9.0" "Skin - Keratinocyte (granular)" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.30e-1)" "prognostic unfavorable (7.03e-4)" "unprognostic (1.56e-2)" "unprognostic (1.46e-1)" CRNN "C1orf10, SEP53" ENSG00000143536 Cornulin Q9UBG3 1 152409243-152414263 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5346.2;vagina: 1691.7" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1997.3" "Group enriched" "Detected in many" 18 "cervical cancer: 19.3;head and neck cancer: 74.0;stomach cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 38 "cervical cancer: 48.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024343, CAB026182" Enhanced NA NA 100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026182: , HPA024343: AB_1847162" "unprognostic (1.96e-2)" "unprognostic (1.74e-6)" "unprognostic (4.20e-2)" "unprognostic (3.43e-1)" "unprognostic (6.43e-3)" CRYBG2 "AIM1L, FLJ38020" ENSG00000176092 "Crystallin beta-gamma domain containing 2" Q8N1P7 1 26321698-26360080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.2;skin 1: 20.3;vagina: 20.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.1;Distal enterocytes: 15.7;Squamous epithelial cells: 15.9;Suprabasal keratinocytes: 34.4;Syncytiotrophoblasts: 61.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 14.5" "Colon - Colon enterocytes, Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA029629 Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA029629: AB_10601331" "unprognostic (2.20e-1)" "unprognostic (2.07e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.11e-6)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (6.39e-4)" "unprognostic (1.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.94e-2)" "unprognostic (4.83e-9)" "unprognostic (9.12e-3)" "unprognostic (3.40e-1)" "unprognostic (6.44e-2)" "unprognostic (1.63e-2)" CRYGS CRYG8 ENSG00000213139 "Crystallin gamma S" P22914 3 186538441-186546702 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.5" "Cell type enhanced" "Detected in some" "Astrocytes: 5.1;Excitatory neurons: 5.3;Inhibitory neurons: 5.9;Microglial cells: 5.5;Oligodendrocyte precursor cells: 5.8;Oligodendrocytes: 7.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA035103, HPA063539" Supported Uncertain Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 52: Spermatids - Smell perception" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA035103: AB_10696367, HPA063539: " "unprognostic (5.52e-4)" "unprognostic (1.29e-3)" "unprognostic (1.44e-2)" "unprognostic (5.45e-2)" "unprognostic (4.90e-2)" "unprognostic (5.85e-2)" "unprognostic (4.79e-2)" "unprognostic (1.73e-2)" "unprognostic (4.76e-2)" "unprognostic (1.12e-1)" "unprognostic (5.84e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.72e-9)" "unprognostic (1.10e-1)" "unprognostic (9.53e-2)" "unprognostic (3.67e-1)" "prognostic favorable (2.73e-4)" CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1693.4;Basal respiratory cells: 2195.1;Squamous epithelial cells: 3654.5;Suprabasal keratinocytes: 10268.1" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cancer enhanced" "Detected in many" "cervical cancer: 269.7;head and neck cancer: 316.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "esophagus: 11304.7" "Cell type enriched" "Detected in all" 4 "Suprabasal keratinocytes: 27723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 8700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Nucleoli "CAB047320: , HPA017380: AB_1847414, HPA058557: AB_2683755" "unprognostic (1.69e-1)" "unprognostic (3.35e-1)" "unprognostic (2.09e-1)" "unprognostic (3.05e-2)" "unprognostic (3.05e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (6.66e-5)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (3.63e-1)" "unprognostic (4.88e-1)" "unprognostic (4.24e-2)" "unprognostic (1.24e-1)" CSTF2 CstF-64 ENSG00000101811 "Cleavage stimulation factor subunit 2" P33240 X 100820359-100841520 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000427, CAB004680" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 48: Non-specific - RNA binding" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "Nuclear bodies" "CAB004680: AB_425385, HPA000427: AB_1078580" "unprognostic (2.02e-2)" "unprognostic (8.70e-3)" "unprognostic (3.50e-1)" "unprognostic (3.43e-1)" "unprognostic (7.00e-2)" "unprognostic (1.09e-2)" "prognostic unfavorable (8.23e-6)" "unprognostic (2.02e-1)" "unprognostic (4.82e-2)" "unprognostic (2.08e-3)" "unprognostic (5.98e-3)" "unprognostic (2.75e-1)" "prognostic favorable (1.12e-4)" "unprognostic (1.75e-2)" "unprognostic (2.90e-2)" "unprognostic (8.75e-2)" "unprognostic (2.89e-1)" CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 35: Liver cancer - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.7;Distal enterocytes: 26.6;Endometrial ciliated cells: 40.2;Glandular and luminal cells: 20.8;Prostatic glandular cells: 81.9;Respiratory ciliated cells: 27.3;Suprabasal keratinocytes: 66.5" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 18.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 62.6;Hepatocytes: 110.7;Proximal enterocytes: 55.0;Squamous epithelial cells: 28.1;Suprabasal keratinocytes: 63.0" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 11.2;liver cancer: 4.2;ovarian cancer: 3.3" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Cell type enriched" "Detected in many" 6 "Suprabasal keratinocytes: 536.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2831.9;Proximal tubular cells: 2882.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" DHRS1 "FLJ25430, MGC20204, SDR19C1" ENSG00000157379 "Dehydrogenase/reductase 1" Q96LJ7 14 24290598-24299780 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 68.9;liver: 61.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 178.3;Suprabasal keratinocytes: 162.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000599, HPA076886" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "Centrosome, Cytosol" "HPA000599: AB_1078655, HPA076886: " "unprognostic (2.08e-3)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (2.75e-1)" "unprognostic (3.57e-1)" "unprognostic (6.57e-2)" "prognostic favorable (1.18e-5)" "prognostic favorable (6.83e-4)" "unprognostic (3.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (9.88e-2)" "unprognostic (2.25e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 472.3;Squamous epithelial cells: 829.7;Suprabasal keratinocytes: 1514.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cancer enhanced" "Detected in many" "testis cancer: 43.4" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Endoplasmic reticulum" "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 29.3" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 6.3;Serous glandular cells: 6.7;Suprabasal keratinocytes: 24.1" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 52: Spermatids - Smell perception" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 107.5;Fibroblasts: 105.1;Melanocytes: 92.3;Suprabasal keratinocytes: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 171.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" EML3 "ELP95, FLJ35827" ENSG00000149499 "EMAP like 3" Q32P44 11 62602218-62612775 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 83.1;Suprabasal keratinocytes: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 64: Macrophages - Immune response" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.08e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-3)" "unprognostic (2.11e-1)" "unprognostic (4.56e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-2)" "unprognostic (1.07e-1)" "unprognostic (5.36e-2)" "unprognostic (9.46e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.13e-8)" "unprognostic (1.42e-1)" "unprognostic (2.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.52e-1)" ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.9;vagina: 31.0" "Group enriched" "Detected in some" 10 "Suprabasal keratinocytes: 94.1;Syncytiotrophoblasts: 66.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" NA NA 14000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA012388: AB_1854860, HPA067448: AB_2685843" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.29e-4)" "unprognostic (6.50e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 13.3;Basal squamous epithelial cells: 13.0;Squamous epithelial cells: 7.6;Suprabasal keratinocytes: 35.5;Thymic epithelial cells: 22.5" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 13.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 21.9;Squamous epithelial cells: 33.3;Suprabasal keratinocytes: 34.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.9;skin 1: 76.5;vagina: 36.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.0;Club cells: 18.6;Ionocytes: 14.6;Serous glandular cells: 13.5;Squamous epithelial cells: 37.6;Suprabasal keratinocytes: 68.3" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.5;lung cancer: 2.5;pancreatic cancer: 2.1;testis cancer: 3.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 166.3;Proximal enterocytes: 216.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Centrosome,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Centrosome, Cytosol" "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 19.0;Squamous epithelial cells: 8.2;Suprabasal keratinocytes: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 281.2;skin 1: 147.4;vagina: 101.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 42.9;Basal keratinocytes: 40.2;Squamous epithelial cells: 103.7;Suprabasal keratinocytes: 174.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 143.3;esophagus: 519.5;salivary gland: 140.0;skin 1: 175.0;vagina: 193.1" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 124.2" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 53.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 10.4;head and neck cancer: 9.5" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" HPA044808 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA044808: AB_2679096" "unprognostic (9.94e-2)" "unprognostic (2.57e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-5)" "unprognostic (1.21e-1)" GBP6 DKFZp686G0786 ENSG00000183347 "Guanylate binding protein family member 6" Q6ZN66 1 89364059-89388160 "Predicted intracellular proteins" Immunity "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 327.3" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 278.4;Squamous epithelial cells: 442.8;Suprabasal keratinocytes: 882.8" "Group enriched" "Detected in many" 7 "cervical cancer: 21.7;head and neck cancer: 38.1;lung cancer: 14.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 9.0;Esophageal cancer: 12.8;Gallbladder cancer: 15.9;head and neck cancer: 9.0" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" HPA027744 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA027744: AB_10602809" "unprognostic (7.60e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (7.05e-3)" "unprognostic (5.85e-2)" "unprognostic (5.66e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "unprognostic (7.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.04e-6)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (3.91e-3)" GID8 "bA305P22.1, C20orf11, FLJ20602, TWA1" ENSG00000101193 "GID complex subunit 8 homolog" Q9NWU2 20 62938147-62948475 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049929, HPA055047" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "Cell Junctions" "HPA049929: AB_2680957, HPA055047: AB_2682682" "unprognostic (1.35e-1)" "unprognostic (4.06e-2)" "unprognostic (5.90e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.19e-1)" "unprognostic (8.25e-2)" "unprognostic (3.88e-2)" "unprognostic (4.58e-2)" "unprognostic (2.16e-1)" "unprognostic (1.83e-1)" "unprognostic (2.72e-2)" "unprognostic (1.43e-1)" "prognostic favorable (3.22e-4)" "unprognostic (3.97e-1)" "unprognostic (1.43e-1)" "unprognostic (2.01e-1)" "unprognostic (6.87e-2)" GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 232.7;Basal respiratory cells: 224.2;Basal squamous epithelial cells: 101.7;Squamous epithelial cells: 178.2;Suprabasal keratinocytes: 624.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 113.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;esophagus: 195.4;vagina: 139.3" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 352.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Cancer enhanced" "Detected in many" "cervical cancer: 135.9;head and neck cancer: 52.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" GLTP ENSG00000139433 "Glycolipid transfer protein" Q9NZD2 12 109850945-109880541 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 334.1;skin 1: 276.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 303.4;Suprabasal keratinocytes: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056461, HPA065503" Approved Supported Cytosol NA NA 25000 "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA056461: AB_2683138, HPA065503: " "unprognostic (1.18e-1)" "prognostic favorable (2.01e-5)" "unprognostic (7.46e-2)" "unprognostic (6.22e-3)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (6.63e-2)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (2.47e-1)" "unprognostic (3.03e-1)" "unprognostic (4.83e-2)" "unprognostic (4.46e-2)" "unprognostic (2.20e-1)" "prognostic favorable (4.17e-6)" "unprognostic (3.28e-2)" GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67737118-67754388 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pituitary gland: 5.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.2;Granulosa cells: 1.8;Inhibitory neurons: 1.3;Suprabasal keratinocytes: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013424 Enhanced NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 47: Retina - Visual perception" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA013424: AB_2668840" "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.78e-1)" "unprognostic (4.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.63e-1)" "unprognostic (9.03e-2)" "unprognostic (3.23e-2)" "unprognostic (9.67e-2)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 119.6;skin 1: 87.7;vagina: 66.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 61.7;Extravillous trophoblasts: 87.3;Suprabasal keratinocytes: 152.5;Syncytiotrophoblasts: 190.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: BEWO - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm Vesicles "HPA005798: AB_1079026, HPA006420: AB_1079025" "unprognostic (2.26e-3)" "unprognostic (5.80e-2)" "unprognostic (8.35e-2)" "unprognostic (7.33e-3)" "unprognostic (2.70e-1)" "unprognostic (2.76e-2)" "unprognostic (4.43e-3)" "unprognostic (6.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-4)" "unprognostic (3.66e-1)" "unprognostic (3.40e-1)" "unprognostic (4.04e-2)" "unprognostic (2.14e-1)" HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 620.7;Suprabasal keratinocytes: 642.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA016928: AB_1850572" "unprognostic (8.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.92e-2)" "unprognostic (6.88e-2)" "unprognostic (7.96e-2)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (1.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.47e-5)" "unprognostic (2.76e-3)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.07e-4)" HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 716.7;skin 1: 1439.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3331.4;Alveolar cells type 2: 2015.8;NK-cells: 722.2;Suprabasal keratinocytes: 1290.6" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 518.2;NK-cell: 781.6" "Group enriched" "Detected in all" 15 "NK-cells: 781.6;T-cells: 518.2" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.9;Club cells: 15.2;Endometrial ciliated cells: 10.4;Respiratory ciliated cells: 26.8;Suprabasal keratinocytes: 42.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 2.4" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 113.0;salivary gland: 34.5;vagina: 31.6" "Cell type enriched" "Detected in some" 41 "Suprabasal keratinocytes: 455.4" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 20.4;Bladder cancer: 25.8;Gallbladder cancer: 14.7;head and neck cancer: 41.1;ovarian cancer: 16.8;pancreatic cancer: 12.7" HPA014001 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA014001: AB_2668919" "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 328.0;Hofbauer cells: 405.7;Langerhans cells: 381.7;Squamous epithelial cells: 531.3;Suprabasal keratinocytes: 1063.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cancer enhanced" "Detected in many" "cervical cancer: 66.3;Gallbladder cancer: 146.8" "Heart muscle - Neutrophils, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "esophagus: 411.3;lymphoid tissue: 115.4" "Cell type enhanced" "Detected in some" "Serous glandular cells: 2.2;Suprabasal keratinocytes: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.5" "Not detected" "Not detected" "Secreted to blood" NA NA 249000 "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.37e-1)" "unprognostic (9.66e-3)" "unprognostic (5.46e-1)" IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 9.1;Suprabasal keratinocytes: 9.4;Syncytiotrophoblasts: 4.4" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 3.8;head and neck cancer: 3.9" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 162.3;esophagus: 298.3;salivary gland: 94.5;skin 1: 160.9;vagina: 235.2" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 1010.6" "Group enriched" "Detected in many" 5 "cervical cancer: 44.0;head and neck cancer: 145.4;melanoma: 50.9;urothelial cancer: 47.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder cancer: 44.6;breast cancer: 13.5;cervical cancer: 23.1;head and neck cancer: 54.0" "Prostate - Urothelial cells" "Not detected" "Not detected" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 4700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Nuclear bodies, Centrosome" "CAB002243: AB_563785, HPA055211: AB_2682739" "unprognostic (3.29e-4)" "unprognostic (1.91e-1)" "unprognostic (2.92e-2)" "unprognostic (2.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.22e-2)" "unprognostic (1.32e-1)" KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 129.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.0" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" KCTD11 "C17orf36, KCASH1, REN" ENSG00000213859 "Potassium channel tetramerization domain containing 11" Q693B1 17 7351889-7354944 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Ubl conjugation pathway" "Developmental protein, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 31.7;Suprabasal keratinocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.6" "Group enriched" "Detected in all" 4 "granulocytes: 9.6;monocytes: 3.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052035 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA052035: AB_2681704" "unprognostic (1.98e-1)" "unprognostic (5.67e-2)" "unprognostic (1.08e-1)" "prognostic favorable (9.55e-4)" "unprognostic (6.78e-3)" "unprognostic (1.92e-2)" "unprognostic (2.38e-2)" "unprognostic (1.59e-3)" "unprognostic (3.91e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (7.93e-2)" "unprognostic (3.62e-1)" "unprognostic (1.99e-1)" "unprognostic (2.03e-1)" "unprognostic (8.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.01e-2)" KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.6;Club cells: 277.7;Ionocytes: 235.2;Late spermatids: 357.1;Squamous epithelial cells: 216.3;Suprabasal keratinocytes: 650.5;Thymic epithelial cells: 309.5" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 99.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid - Parafollicular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 228.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.1;lung cancer: 5.8" "Lung - Respiratory ciliated cells, Testis - Late spermatids, Thyroid - Parafollicular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 519.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 62.6;Late spermatids: 249.3;Serous glandular cells: 56.1;Squamous epithelial cells: 100.4;Suprabasal keratinocytes: 215.7" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 8.0;Esophageal cancer: 5.1;head and neck cancer: 2.7;ovarian cancer: 10.1;Rhabdoid: 3.1" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152759561-152762052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 329.1" "Cell type enriched" "Detected in single" 37 "Suprabasal keratinocytes: 17.5" "Group enriched" "Detected in some" 22 "head and neck cancer: 6.9;melanoma: 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "thyroid cancer: 19.1" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 27000000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA031988: AB_10671582, HPA031990: AB_2674102" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 20502.7;Suprabasal keratinocytes: 65697.5" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "cervical cancer: 3951.7" "Prostate - Urothelial cells" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.0;salivary gland: 10.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 858.4" "Group enriched" "Detected in some" 5 "cervical cancer: 0.7;head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.3;lymphoma: 2.6" "Skin - Keratinocyte (other)" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" NA NA 280000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (2.75e-1)" "unprognostic (9.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.73e-2)" KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 82.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 3.1;Ionocytes: 1.1;Salivary duct cells: 1.0;Suprabasal keratinocytes: 5.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Testis - Late spermatids" HPA055194 Supported NA NA 350000000 "Cluster 61: Skin - Cornification" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Group enriched" "Detected in some" 29 "Squamous epithelial cells: 7509.7;Suprabasal keratinocytes: 21955.2" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cervical cancer: 1905.1;Gallbladder cancer: 1382.4" "Prostate - Urothelial cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5655.3;Serous glandular cells: 2866.1;Suprabasal keratinocytes: 12245.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 2653.9;head and neck cancer: 1568.8" "Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 733.1;Serous glandular cells: 447.8;Squamous epithelial cells: 269.7;Suprabasal keratinocytes: 1893.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "head and neck cancer: 127.5" "Skin - Outer root sheath cells" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 945.7;Serous glandular cells: 543.3;Squamous epithelial cells: 298.3;Suprabasal keratinocytes: 2295.0" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 32.3;head and neck cancer: 15.9" "Skin - Outer root sheath cells" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" KRT76 "HUMCYT2A, KRT2B, KRT2P" ENSG00000185069 "Keratin 76" Q01546 12 52768155-52777345 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "lymphoid tissue: 2.5;salivary gland: 2.6" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 857.8" "Cancer enriched" "Detected in single" 12 "head and neck cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA019656, HPA019696" Approved NA NA 310000000 "Cluster 16: Immune cells - Immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA019656: AB_1852241, HPA019696: AB_1852243" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" KRT78 K5B ENSG00000170423 "Keratin 78" Q8N1N4 12 52837804-52849092 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 972.7" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 270.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.8;Gallbladder cancer: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA039724 Enhanced NA NA 70000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA039724: AB_10795255" "unprognostic (5.36e-2)" "unprognostic (5.89e-2)" "unprognostic (2.95e-2)" "unprognostic (3.25e-2)" "unprognostic (1.88e-1)" "unprognostic (2.18e-2)" "unprognostic (3.01e-3)" "unprognostic (8.88e-16)" "unprognostic (3.50e-2)" "unprognostic (6.92e-1)" "unprognostic (7.55e-2)" "unprognostic (1.25e-1)" KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skin 1: 6146.5;vagina: 1735.6" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 8540.3" "Group enriched" "Detected in many" 7 "head and neck cancer: 486.4;melanoma: 207.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Esophageal cancer: 41.4;head and neck cancer: 64.9" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" NA NA 34000000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA063474: AB_2685019" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.50e-1)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 153.0;Distal enterocytes: 137.3;Ductal cells: 158.2;Proximal enterocytes: 235.7;Squamous epithelial cells: 215.3;Suprabasal keratinocytes: 358.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 251.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" LCE3D "LEP16, SPRL6A, SPRL6B" ENSG00000163202 "Late cornified envelope 3D" Q9BYE3 1 152579381-152580516 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 272.5;lymphoid tissue: 84.8;skin 1: 84.1;vagina: 229.7" "Cell type enriched" "Detected in some" 9 "Suprabasal keratinocytes: 15.2" "Group enriched" "Detected in many" 9 "head and neck cancer: 126.9;melanoma: 47.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 27.8" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" LCE3E LEP17 ENSG00000185966 "Late cornified envelope 3E" Q5T5B0 1 152565654-152566780 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 96.8;vagina: 49.1" "Cell type enriched" "Detected in single" 8 "Suprabasal keratinocytes: 2.9" "Group enriched" "Detected in some" 9 "head and neck cancer: 40.7;melanoma: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 14.5" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.33e-1)" "unprognostic (7.76e-2)" "unprognostic (2.51e-1)" LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88724544-88752756 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other), Stomach - Chief cells" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" LY6G6C "C6orf24, G6c, NG24" ENSG00000204421 "Lymphocyte antigen 6 family member G6C" O95867 6 31718648-31721746 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "skin 1: 511.5" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 151.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.3" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.21e-1)" "unprognostic (3.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.85e-3)" "unprognostic (2.59e-3)" "unprognostic (1.35e-1)" "unprognostic (9.03e-2)" "unprognostic (1.79e-1)" "unprognostic (4.13e-1)" "unprognostic (1.76e-3)" "unprognostic (2.85e-1)" "unprognostic (8.80e-7)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.09e-2)" "unprognostic (9.38e-2)" LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 573.0;Squamous epithelial cells: 889.9;Suprabasal keratinocytes: 2645.8;Syncytiotrophoblasts: 1067.1" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 69.6" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" MAB21L3 "C1orf161, FLJ38716" ENSG00000173212 "Mab-21 like 3" Q8N8X9 1 116111755-116135240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;esophagus: 7.0;skin 1: 6.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 13.0;Inhibitory neurons: 9.9;Oligodendrocytes: 29.8;Suprabasal keratinocytes: 8.7;Syncytiotrophoblasts: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 11.1" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 6.2" HPA039551 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA039551: AB_2676565" "unprognostic (9.25e-3)" "unprognostic (3.47e-3)" "unprognostic (1.44e-3)" "unprognostic (5.23e-5)" "unprognostic (2.22e-1)" "unprognostic (2.06e-2)" "unprognostic (5.36e-2)" "unprognostic (3.75e-3)" "unprognostic (1.21e-1)" "unprognostic (7.01e-2)" "unprognostic (2.49e-1)" "unprognostic (4.84e-2)" "unprognostic (1.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (4.61e-2)" MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 262.6;vagina: 80.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 95.6;Enteroendocrine cells: 32.6;Paneth cells: 63.1;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 69.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 24.4" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.86e-3)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (6.46e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enriched" "Detected in many" 4 "Suprabasal keratinocytes: 1696.8" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cancer enhanced" "Detected in many" "Leukemia: 36.0;ovarian cancer: 67.9;Uterine cancer: 47.3" "Adipose subcutaneous - Smooth muscle cells, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 395.3;Collecting duct cells: 338.7;Distal enterocytes: 308.7;Squamous epithelial cells: 323.3;Suprabasal keratinocytes: 588.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" MFSD5 "HsMOT2, MGC11308" ENSG00000182544 "Major facilitator superfamily domain containing 5" Q6N075 12 53251251-53254406 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039773 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA039773: AB_10793920" "unprognostic (9.42e-3)" "unprognostic (9.03e-3)" "unprognostic (4.25e-2)" "unprognostic (1.10e-1)" "unprognostic (1.37e-2)" "unprognostic (5.04e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (2.20e-2)" "unprognostic (1.69e-1)" "unprognostic (4.25e-1)" "unprognostic (9.79e-2)" "unprognostic (4.52e-2)" "unprognostic (5.63e-2)" "unprognostic (1.65e-2)" "unprognostic (2.12e-1)" "unprognostic (6.51e-3)" "unprognostic (1.19e-2)" MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAPK interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 475.7;tongue: 551.1" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 294.0;Suprabasal keratinocytes: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: AB_2732157" "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favorable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favorable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 91.1;Excitatory neurons: 75.5;Suprabasal keratinocytes: 83.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 135.8;esophagus: 696.3;vagina: 244.5" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 524.9" "Group enriched" "Detected in many" 9 "cervical cancer: 6.8;head and neck cancer: 6.6;lung cancer: 13.9;stomach cancer: 7.0;thyroid cancer: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "lung cancer: 2.2" "Lung - Alveolar cells type 2" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA052028: AB_2681700" "unprognostic (2.27e-2)" "unprognostic (4.85e-3)" "unprognostic (5.24e-3)" "unprognostic (1.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.98e-3)" "unprognostic (1.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" MYH13 MyHC-eo ENSG00000006788 "Myosin heavy chain 13" Q9UKX3 17 10300865-10373130 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.5;stomach 1: 1.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.5;Inhibitory neurons: 1.4;Spermatogonia: 1.9;Suprabasal keratinocytes: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA 29000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 17: RS4;11 - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (8.86e-2)" "unprognostic (2.45e-2)" "unprognostic (7.81e-2)" "unprognostic (3.95e-1)" "unprognostic (8.35e-2)" "unprognostic (1.42e-2)" "unprognostic (7.50e-3)" "unprognostic (3.15e-2)" "unprognostic (1.08e-1)" "unprognostic (8.74e-2)" "unprognostic (3.40e-9)" "unprognostic (2.44e-2)" "unprognostic (1.08e-1)" "unprognostic (2.06e-2)" NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 198.5;Suprabasal keratinocytes: 202.7;Syncytiotrophoblasts: 314.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 391.8;granulocytes: 288.7;monocytes: 594.1" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 1000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" NBEAL2 KIAA0540 ENSG00000160796 "Neurobeachin like 2" Q6ZNJ1 3 46979666-47009704 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 134.7;Gastric mucus-secreting cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 4.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051969 Approved NA NA 31000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 5: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA051969: " "unprognostic (3.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.37e-2)" "unprognostic (5.99e-3)" "prognostic favorable (4.60e-4)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (6.27e-2)" "unprognostic (5.29e-2)" "unprognostic (1.06e-3)" "unprognostic (3.75e-1)" "unprognostic (6.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.34e-2)" NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.5;Suprabasal keratinocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" NIPAL1 "DKFZp686A06115, NPAL1" ENSG00000163293 "NIPA like domain containing 1" Q6NVV3 4 47914142-48040173 "Predicted membrane proteins" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.8;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 39.4;Distal enterocytes: 49.6;Paneth cells: 38.4;Squamous epithelial cells: 52.6;Suprabasal keratinocytes: 77.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA036765 Uncertain Approved "Golgi apparatus" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA036765: AB_10672366" "unprognostic (3.03e-1)" "unprognostic (4.55e-2)" "unprognostic (2.34e-3)" "unprognostic (2.18e-2)" "unprognostic (1.12e-2)" "unprognostic (3.57e-1)" "unprognostic (9.55e-2)" "unprognostic (4.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (3.71e-3)" "unprognostic (1.34e-1)" "unprognostic (9.03e-7)" "unprognostic (2.55e-1)" "unprognostic (3.73e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 43.2" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.4" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061516 Supported Supported "Plasma membrane,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 3: Suprabasal keratinocytes - Cornification" Mitochondria "Plasma membrane" "HPA061516: AB_2684548" "unprognostic (7.58e-2)" "unprognostic (3.71e-1)" "unprognostic (6.36e-2)" "prognostic favorable (2.47e-5)" "unprognostic (5.60e-3)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (8.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.59e-6)" "unprognostic (3.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (4.22e-2)" NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47624665 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol No No 3000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA021453: AB_2670709, HPA045649: AB_2679406" "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "prognostic favorable (3.39e-5)" "unprognostic (2.66e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (8.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 47.2;Endometrial ciliated cells: 44.4;Glandular and luminal cells: 51.7;Intestinal goblet cells: 45.8;Suprabasal keratinocytes: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 45.6" "Pancreas - Ductal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" NUDT8 FLJ41567 ENSG00000167799 "Nudix hydrolase 8" Q8WV74 11 67627938-67629937 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 227.2;Proximal enterocytes: 160.2;Proximal tubular cells: 222.2;Squamous epithelial cells: 146.4;Suprabasal keratinocytes: 179.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "HPA041252, HPA041466" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: Myeloma - Humoral immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoli Cytosol "HPA041252: AB_10794551, HPA041466: AB_10793967" "unprognostic (8.31e-2)" "unprognostic (7.26e-3)" "unprognostic (7.31e-2)" "unprognostic (7.32e-2)" "unprognostic (2.87e-1)" "unprognostic (2.36e-3)" "unprognostic (2.69e-1)" "unprognostic (4.12e-2)" "unprognostic (8.28e-2)" "unprognostic (2.69e-2)" "unprognostic (3.11e-2)" "unprognostic (2.74e-1)" "prognostic favorable (3.70e-4)" "unprognostic (4.70e-2)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (2.19e-1)" OTOP3 ENSG00000182938 "Otopetrin 3" 17 74935898-74949992 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "intestine: 79.6" "Cell type enhanced" "Detected in some" "Paneth cells: 71.0;Proximal enterocytes: 14.2;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 22.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 28.9;thyroid cancer: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (9.28e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.77e-1)" "unprognostic (8.60e-2)" "unprognostic (3.42e-1)" "unprognostic (1.03e-1)" "unprognostic (8.36e-2)" PAX1 ENSG00000125813 "Paired box 1" P15863 20 21705659-21718486 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 162.1" "Cell type enhanced" "Detected in some" "Club cells: 1.6;granulocytes: 1.6;Suprabasal keratinocytes: 2.9" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 14: Bone cancer - Transcription" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (9.74e-2)" "unprognostic (3.45e-2)" "unprognostic (3.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.33e-2)" "unprognostic (4.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (8.08e-2)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.3;Distal enterocytes: 250.2;Extravillous trophoblasts: 189.3;Proximal enterocytes: 184.4;Suprabasal keratinocytes: 357.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 19.1;skin 1: 16.1;vagina: 22.5" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 14.1" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 2.0;melanoma: 1.8;prostate cancer: 1.3;urothelial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gastric cancer: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Ductal cells: 20.2;Exocrine glandular cells: 23.2;Squamous epithelial cells: 41.9;Suprabasal keratinocytes: 72.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 24.0" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;skin 1: 14.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.0;Early spermatids: 1.7;Late spermatids: 1.8;Melanocytes: 1.7;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "head and neck cancer: 9.0;skin cancer: 2.7" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" POLR2J3 ENSG00000168255 "RNA polymerase II subunit J3" 7 102537918-102572653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA011403, HPA046970" Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA011403: AB_2668503, HPA046970: AB_2679882" "unprognostic (3.55e-2)" "unprognostic (2.04e-4)" "unprognostic (4.55e-3)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (9.26e-2)" "unprognostic (2.63e-2)" "unprognostic (1.44e-2)" "unprognostic (7.12e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (1.00e-1)" "unprognostic (5.90e-4)" "unprognostic (3.04e-1)" "unprognostic (7.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-2)" PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 127.9;Salivary duct cells: 101.4;Squamous epithelial cells: 163.2;Suprabasal keratinocytes: 366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 79.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.6;Gastric mucus-secreting cells: 51.3;Intestinal goblet cells: 43.4;Paneth cells: 87.5;Proximal enterocytes: 75.1;Squamous epithelial cells: 56.1;Suprabasal keratinocytes: 82.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 586.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" RAB22A ENSG00000124209 "RAB22A, member RAS oncogene family" Q9UL26 20 58309715-58367507 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066920 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA066920: AB_2685749" "unprognostic (4.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.68e-1)" "unprognostic (8.34e-3)" "unprognostic (6.20e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.12e-1)" "unprognostic (2.00e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-2)" "unprognostic (2.16e-1)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (7.01e-3)" RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 347.3;Suprabasal keratinocytes: 519.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010940, CAB033645" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "CAB033645: AB_1128883, HPA010940: " "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 93.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 28.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (other), Testis - Late spermatids" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 41.4;Respiratory ciliated cells: 20.6;Suprabasal keratinocytes: 40.3;Thymic epithelial cells: 52.0" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 23.2" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 9.6;Basal respiratory cells: 5.3;Collecting duct cells: 11.8;Squamous epithelial cells: 8.1;Suprabasal keratinocytes: 34.2" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 20.0" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Group enriched" "Detected in many" 5 "Squamous epithelial cells: 1909.7;Suprabasal keratinocytes: 4570.8" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 20.4;head and neck cancer: 42.3" "Kidney - Intercalated cells, Prostate - Urothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" RHOD "ARHD, Rho, RhoHP1" ENSG00000173156 "Ras homolog family member D" O00212 11 67056847-67072017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 182.2;liver: 122.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 117.1;Exocrine glandular cells: 112.5;Suprabasal keratinocytes: 237.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Group enriched" "Detected in many" 4 "cerebellum: 14.9;pons and medulla: 5.1" "Low region specificity" "Detected in some" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (2.12e-2)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.89e-3)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (5.85e-2)" "unprognostic (4.39e-2)" "unprognostic (1.38e-3)" "unprognostic (8.89e-2)" "unprognostic (2.56e-2)" "unprognostic (2.24e-1)" "unprognostic (5.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" RNF208 DKFZP761H1710 ENSG00000212864 "Ring finger protein 208" Q9H0X6 9 137220247-137221581 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021256, HPA021429" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA021256: AB_1844331, HPA021429: AB_2180654" "unprognostic (2.97e-1)" "unprognostic (7.37e-2)" "unprognostic (1.46e-2)" "unprognostic (6.33e-3)" "unprognostic (9.99e-2)" "unprognostic (2.10e-3)" "unprognostic (3.52e-3)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.95e-2)" "unprognostic (8.42e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.12e-8)" "unprognostic (3.41e-1)" "unprognostic (1.69e-1)" "unprognostic (7.66e-2)" "unprognostic (3.40e-2)" RNF222 ENSG00000189051 "Ring finger protein 222" A6NCQ9 17 8390704-8397826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.9;skin 1: 6.9;vagina: 5.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;NK-cells: 1.0;Rod photoreceptor cells: 1.3;Suprabasal keratinocytes: 6.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;Gallbladder cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048916 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA048916: AB_2680555" "unprognostic (2.49e-1)" "unprognostic (4.19e-2)" "unprognostic (2.32e-2)" "unprognostic (8.19e-4)" "unprognostic (2.81e-1)" "unprognostic (5.30e-2)" "unprognostic (2.02e-1)" "unprognostic (3.93e-2)" "unprognostic (9.55e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-3)" "unprognostic (5.82e-2)" "unprognostic (6.70e-2)" "unprognostic (5.98e-3)" "unprognostic (3.97e-2)" RNF224 ENSG00000233198 "Ring finger protein 224" P0DH78 9 137227502-137229640 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 3.4;pituitary gland: 5.8" "Cell type enhanced" "Detected in some" "Paneth cells: 1.2;Proximal tubular cells: 2.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA079078 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Golgi apparatus" "HPA079078: " "unprognostic (2.45e-1)" "unprognostic (2.34e-3)" "unprognostic (7.01e-4)" "unprognostic (6.04e-2)" "unprognostic (5.26e-2)" "unprognostic (1.70e-3)" "unprognostic (3.87e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-3)" "unprognostic (4.57e-2)" "unprognostic (5.24e-2)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "unprognostic (4.95e-2)" "unprognostic (1.27e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.3;monocytes: 299.1" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 22000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Cytosol" "HPA039223: AB_10795581, HPA040781: AB_10796227" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.48e-3)" "unprognostic (6.09e-2)" "unprognostic (4.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "prognostic favorable (2.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-2)" "unprognostic (4.35e-2)" RPS6KB2 "KLS, P70-BETA, p70S6Kb, S6Kβ, S6KB, S6Kbeta, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435401 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 203.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" RPTN FLJ39117 ENSG00000215853 Repetin Q6XPR3 1 152153595-152159228 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 52.2;skin 1: 29.7" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 15.7" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "cervical cancer: 6.1" "Not detected" "Not detected" "HPA030483, HPA030485" Enhanced "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA030483: AB_2673495, HPA030485: AB_10601159" "unprognostic (1.37e-2)" "unprognostic (5.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.54e-2)" "unprognostic (4.00e-2)" "unprognostic (5.23e-3)" S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2185.0;Distal enterocytes: 1714.4;Proximal enterocytes: 1543.9;Squamous epithelial cells: 3706.1;Suprabasal keratinocytes: 5461.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 976.3" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 973.9;Squamous epithelial cells: 1202.5;Suprabasal keratinocytes: 2430.8;Theca cells: 1030.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9723.3;Kupffer cells: 12238.3;Squamous epithelial cells: 10710.7;Suprabasal keratinocytes: 41386.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in many" 8 "cervical cancer: 1388.9;head and neck cancer: 849.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11312.8;Hofbauer cells: 6740.0;Kupffer cells: 13272.6;Serous glandular cells: 7302.9;Suprabasal keratinocytes: 51664.6" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 1394.9" "Breast - Macrophages, Colon - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441, CAB080262" Enhanced Supported "Plasma membrane,Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Intermediate filaments, Cytosol" "CAB009441: AB_2184420, CAB080262: , HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 5911.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 385.5;skin 1: 302.7" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 436.4;Suprabasal keratinocytes: 280.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 52.5;pancreatic cancer: 49.6" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: AB_10805485, HPA040154: AB_10795359" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.91e-2)" "unprognostic (4.54e-2)" "unprognostic (6.62e-2)" "unprognostic (3.51e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (1.24e-4)" "unprognostic (4.57e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.81e-1)" "unprognostic (2.82e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (1.73e-5)" SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 261.8;Hepatocytes: 521.4;Squamous epithelial cells: 277.8;Suprabasal keratinocytes: 460.3;Syncytiotrophoblasts: 426.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 549.2;Myeloma: 636.0" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 29.7" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" SERPINB11 EPIPIN ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 27.4;prostate: 32.5" "Cell type enhanced" "Detected in some" "Club cells: 43.6;Ionocytes: 29.2;Prostatic glandular cells: 24.7;Squamous epithelial cells: 17.6;Suprabasal keratinocytes: 30.5" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (5.04e-3)" "unprognostic (4.76e-2)" "unprognostic (4.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.62e-1)" SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 106.0;Serous glandular cells: 60.4;Squamous epithelial cells: 185.5;Suprabasal keratinocytes: 652.1" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 46.5;Gallbladder cancer: 30.5;head and neck cancer: 31.5" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 36: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: AB_2677317, HPA042986: AB_10960386" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (1.06e-2)" "unprognostic (7.67e-2)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (2.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.60e-1)" "unprognostic (8.76e-2)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 48: Non-specific - RNA binding" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 570.8;Proximal tubular cells: 381.6;Squamous epithelial cells: 348.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967140-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015757, HPA056556" Approved Approved Cytosol NA NA 140000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA015757: AB_1857236, HPA056556: " "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Cell type enriched" "Detected in some" 12 "Suprabasal keratinocytes: 2377.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 1.9;Esophageal cancer: 1.8;head and neck cancer: 3.9" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 870.8;skin 1: 334.1;vagina: 219.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 7.9;Ionocytes: 8.2;Squamous epithelial cells: 28.0;Suprabasal keratinocytes: 27.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 5.5;head and neck cancer: 12.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Secreted in other tissues" NA NA 3100000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.2;dendritic cells: 78.5;Distal tubular cells: 96.4;Endometrial ciliated cells: 72.7;Erythroid cells: 69.4;Glandular and luminal cells: 73.8;Schwann cells: 93.8;Suprabasal keratinocytes: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.6" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.6" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "Golgi apparatus" "HPA065332: AB_2685471, HPA071268: AB_2686377" "unprognostic (6.97e-2)" "prognostic favorable (5.52e-4)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-4)" "unprognostic (3.29e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (3.52e-3)" "unprognostic (1.10e-1)" "prognostic favorable (1.12e-4)" "unprognostic (2.64e-1)" "unprognostic (4.94e-2)" "unprognostic (8.26e-2)" "unprognostic (2.58e-1)" SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 10618.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 31.3" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" SPINK6 "BUSI2, MGC21394, UNQ844" ENSG00000178172 "Serine peptidase inhibitor Kazal type 6" Q6UWN8 5 148202794-148215137 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.7;lymphoid tissue: 4.9;salivary gland: 6.9;vagina: 10.1" "Group enriched" "Detected in some" 4 "Melanocytes: 7.0;Suprabasal keratinocytes: 13.0" "Group enriched" "Detected in many" 6 "cervical cancer: 21.4;head and neck cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 29 "cervical cancer: 1785.1" "Adipose visceral - Adipocytes (Visceral)" "Not detected" "Not detected" "Not detected" "Not detected" HPA011039 Uncertain "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA011039: AB_2668412" "unprognostic (2.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.65e-1)" "unprognostic (4.87e-2)" "prognostic favorable (7.16e-4)" "unprognostic (2.49e-2)" "unprognostic (4.04e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 262.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cervical cancer: 6.5;Esophageal cancer: 3.6;head and neck cancer: 13.7;lung cancer: 4.1" "Skin - Hair cortex cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 18.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 24000 "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 52: Spermatids - Smell perception" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" SPRR1A ENSG00000169474 "Small proline rich protein 1A" P35321 1 152985231-152985500 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 8971.2" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 209.6" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 1736.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 79.3;Esophageal cancer: 84.6;head and neck cancer: 171.2" CAB011237 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB011237: " "unprognostic (1.39e-1)" "unprognostic (5.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.19e-2)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" SPRR1B "GADD33, SPRR1" ENSG00000169469 "Small proline rich protein 1B" P22528 1 153031203-153032900 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1386.5;esophagus: 2237.9;vagina: 1775.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 770.9;Serous glandular cells: 404.8;Suprabasal keratinocytes: 2350.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 1812.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 116.0;Esophageal cancer: 88.0;head and neck cancer: 269.8" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (1.73e-1)" "unprognostic (2.39e-1)" "unprognostic (5.59e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (7.66e-5)" "unprognostic (2.22e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (7.64e-5)" "unprognostic (5.71e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.28e-4)" SPRR2A ENSG00000241794 "Small proline rich protein 2A" P35326 1 153056120-153057512 "Predicted intracellular proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 5262.1" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 2325.4;Serous glandular cells: 1822.6;Suprabasal keratinocytes: 3440.7" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 743.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 45.9;Myeloma: 22.5;pancreatic cancer: 20.3" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (3.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-3)" "unprognostic (1.64e-2)" "unprognostic (6.80e-3)" "unprognostic (3.51e-1)" "unprognostic (3.36e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.37e-5)" SPRR3 ENSG00000163209 "Small proline rich protein 3" Q9UBC9 1 153001747-153003856 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 4257.2;esophagus: 19480.4;vagina: 6062.0" "Cell type enriched" "Detected in some" 12 "Suprabasal keratinocytes: 21062.6" "Group enriched" "Detected in many" 4 "cervical cancer: 206.3;head and neck cancer: 423.4;stomach cancer: 113.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder cancer: 50.4;cervical cancer: 110.1" "Not detected" "Not detected" HPA044467 Enhanced NA NA 5200 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA044467: AB_2678952" "unprognostic (2.78e-2)" "unprognostic (3.54e-1)" "unprognostic (8.77e-2)" "unprognostic (7.50e-3)" "unprognostic (9.67e-3)" "unprognostic (2.36e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.58e-2)" SPRR5 ENSG00000283227 "Small proline rich protein 5" A0A1B0GTR4 1 152947154-152949258 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "skin 1: 115.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Exocrine glandular cells: 2.9;granulocytes: 1.6;Suprabasal keratinocytes: 7.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "head and neck cancer: 3.3" "Skin - Keratinocyte (granular)" NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in all" "Collecting duct cells: 122.1;Cone photoreceptor cells: 113.7;Late spermatids: 73.5;Suprabasal keratinocytes: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" STN1 "bA541N10.2, FLJ22559, OBFC1" ENSG00000107960 "STN1 subunit of CST complex" Q9H668 10 103877569-103918184 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037924, HPA037925" Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA037924: AB_10671636, HPA037925: AB_10672469" "unprognostic (1.50e-1)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (5.58e-3)" "unprognostic (6.01e-2)" "unprognostic (1.53e-2)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (5.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "unprognostic (3.76e-1)" "prognostic favorable (1.12e-6)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.83e-2)" SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.0;skin 1: 186.5;vagina: 145.9" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 548.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 31.2" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles Cytosol "HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: " "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" TARS1 TARS ENSG00000113407 "Threonyl-tRNA synthetase 1" P26639 5 33440696-33468091 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037425 Approved Approved "Actin filaments,Cytosol" NA NA 580000 "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Actin filaments" "HPA037425: AB_10672279" "prognostic unfavorable (6.14e-5)" "unprognostic (5.13e-2)" "unprognostic (9.04e-2)" "prognostic unfavorable (5.17e-4)" "unprognostic (9.10e-2)" "unprognostic (1.07e-3)" "prognostic unfavorable (9.88e-7)" "unprognostic (1.43e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-3)" "unprognostic (5.97e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (1.37e-1)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (7.25e-2)" TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 970.3;Suprabasal keratinocytes: 675.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 3: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Group enriched" "Detected in many" 4 "Suprabasal keratinocytes: 400.1;Thymic epithelial cells: 116.1" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 33.3;head and neck cancer: 20.9" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341079 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "esophagus: 1838.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.1;Enteroendocrine cells: 19.8;Squamous epithelial cells: 13.1;Suprabasal keratinocytes: 63.4" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 295 "neutrophil: 30.3" "Lineage enriched" "Detected in single" 303 "granulocytes: 30.3" "Cancer enriched" "Detected in some" 19 "Rhabdoid: 121.9" "Lung - Respiratory ciliated cells, Testis - Early spermatids" HPA004728 Approved NA NA 14000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847101-151853712 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "skin 1: 158.5" "Cell type enriched" "Detected in some" 9 "Suprabasal keratinocytes: 149.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 4.0;hippocampal formation: 3.0;white matter: 1.0" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Cancer enhanced" "Detected in many" "lymphoma: 12.9" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 13.8" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Enzymes" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.3;skin 1: 58.5" "Cell type enhanced" "Detected in many" "B-cells: 107.6;Basal keratinocytes: 83.0;granulocytes: 116.0;monocytes: 85.3;Squamous epithelial cells: 109.2;Suprabasal keratinocytes: 309.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 403.7;eosinophil: 305.7;neutrophil: 477.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 477.5" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear membrane" Nucleoplasm "HPA019184: AB_2670088, HPA055411: " "unprognostic (1.09e-1)" "unprognostic (3.56e-1)" "unprognostic (5.17e-2)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.65e-1)" "unprognostic (5.00e-3)" "unprognostic (7.67e-2)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 94.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 45.0;Intestinal goblet cells: 36.3;Proximal enterocytes: 53.9;Respiratory ciliated cells: 36.8;Suprabasal keratinocytes: 55.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.5" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 63: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 45.3;Squamous epithelial cells: 67.4;Suprabasal keratinocytes: 163.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 378.6;Suprabasal keratinocytes: 272.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 86.1;lymphoid tissue: 28.4;vagina: 41.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.0;Serous glandular cells: 17.9;Squamous epithelial cells: 60.5;Suprabasal keratinocytes: 30.3" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.5" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA078316: " "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" TMPRSS11B HATL5 ENSG00000185873 "Transmembrane serine protease 11B" Q86T26 4 68226653-68245694 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 390.7;lymphoid tissue: 82.2;vagina: 118.3" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 39.5;Serous glandular cells: 53.6;Suprabasal keratinocytes: 127.4" "Group enriched" "Detected in some" 12 "cervical cancer: 2.6;head and neck cancer: 2.6;stomach cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "cervical cancer: 1.4" "Low region specificity" "Detected in many" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (4.24e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.92e-1)" "unprognostic (3.96e-1)" TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "cervix: 51.6;esophagus: 71.8;lymphoid tissue: 34.4;salivary gland: 21.0;vagina: 76.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 59.6;Basal respiratory cells: 24.3;Serous glandular cells: 49.2;Suprabasal keratinocytes: 125.4" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 1.3;Esophageal cancer: 2.2;head and neck cancer: 1.8;lymphoma: 2.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA077704: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 89.5;esophagus: 220.2;salivary gland: 56.7;vagina: 156.3" "Group enriched" "Detected in some" 6 "Ionocytes: 74.4;Salivary duct cells: 84.2;Suprabasal keratinocytes: 68.0" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 7.9;head and neck cancer: 5.7" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Enhanced Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 46: Non-specific - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA043816: , HPA051062: AB_2681329" "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 15.2;skin 1: 9.3;vagina: 4.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Cytotrophoblasts: 1.6;Squamous epithelial cells: 7.6;Suprabasal keratinocytes: 8.7" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.5;lymphoma: 2.2" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 41.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Extravillous trophoblasts: 22.9;Glandular and luminal cells: 11.8;Salivary duct cells: 14.2;Suprabasal keratinocytes: 21.5;Syncytiotrophoblasts: 21.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.9" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA079555 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Plasma membrane" "HPA079555: " "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 24.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 11 "basophil: 1.7;eosinophil: 2.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.7" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA054060 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 17: RS4;11 - Unknown function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA054060: AB_2682362" "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 104.2;Suprabasal keratinocytes: 141.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 35.6;Skeletal myocytes: 94.0;Squamous epithelial cells: 41.5;Suprabasal keratinocytes: 84.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.6;vagina: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.9;Intestinal goblet cells: 31.1;Paneth cells: 32.9;Proximal enterocytes: 51.7;Squamous epithelial cells: 22.9;Suprabasal keratinocytes: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035072 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" TTC9 "KIAA0227, TTC9A" ENSG00000133985 "Tetratricopeptide repeat domain 9" Q92623 14 70641916-70675366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.1" "Cell type enhanced" "Detected in many" "Ionocytes: 33.3;Respiratory ciliated cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079473 Approved "Nuclear bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "Nuclear bodies" "HPA079473: " "unprognostic (2.37e-2)" "unprognostic (6.01e-2)" "unprognostic (9.29e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.81e-2)" "unprognostic (2.38e-2)" "unprognostic (2.53e-2)" "unprognostic (7.12e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.18e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.10e-8)" "unprognostic (1.22e-2)" "unprognostic (1.01e-1)" "unprognostic (3.16e-2)" "unprognostic (9.38e-2)" TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 479.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1311.4;Suprabasal keratinocytes: 843.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 98.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039247, HPA043684, HPA063394" Supported Supported Microtubules NA Yes 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-2)" "prognostic favorable (7.37e-5)" "unprognostic (3.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.88e-2)" "prognostic unfavorable (8.48e-8)" "prognostic unfavorable (6.85e-4)" "unprognostic (2.11e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (5.64e-6)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.26e-7)" "unprognostic (2.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (5.45e-3)" TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in all" "Horizontal cells: 292.9;Suprabasal keratinocytes: 533.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cancer enhanced" "Detected in all" "testis cancer: 365.5" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: Skin cancer - Membrane components" "Cluster 3: Suprabasal keratinocytes - Cornification" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" UNC93A "dJ366N23.1, dJ366N23.2" ENSG00000112494 "Unc-93 homolog A" Q86WB7 6 167271169-167316014 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "esophagus: 5.1;intestine: 9.6;liver: 14.1;skin 1: 19.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.8;Endometrial ciliated cells: 2.1;Hepatocytes: 6.3;Proximal enterocytes: 3.4;Suprabasal keratinocytes: 2.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.4;Gastric cancer: 9.0;liver cancer: 3.7" "Liver - Hepatocytes" "Not detected" "Not detected" HPA035729 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA035729: AB_10696508" "unprognostic (2.49e-1)" "unprognostic (2.67e-1)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.26e-1)" "unprognostic (2.32e-1)" "unprognostic (2.10e-1)" "unprognostic (3.32e-3)" "unprognostic (2.99e-2)" "unprognostic (5.97e-3)" "unprognostic (1.85e-1)" "unprognostic (4.92e-2)" UPK1A TSPAN21 ENSG00000105668 "Uroplakin 1A" O00322 19 35666516-35678483 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 43.2;urinary bladder: 205.7;vagina: 52.4" "Cell type enriched" "Detected in some" 5 "Club cells: 69.5" "Cancer enriched" "Detected in many" 41 "urothelial cancer: 148.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Bladder cancer: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049879 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA049879: AB_2680929" "unprognostic (3.29e-1)" "unprognostic (1.78e-1)" "unprognostic (1.19e-3)" "unprognostic (3.40e-4)" "unprognostic (4.05e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-2)" "unprognostic (3.11e-3)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (2.34e-1)" "unprognostic (2.48e-9)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (2.45e-2)" "unprognostic (1.72e-1)" VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342124 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 20.3;esophagus: 62.3;salivary gland: 23.5;vagina: 22.3" "Group enriched" "Detected in many" 4 "Serous glandular cells: 18.8;Suprabasal keratinocytes: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA060453: AB_2684280, HPA066745: AB_2685712" "unprognostic (1.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.98e-3)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.75e-4)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-4)" "unprognostic (1.42e-2)" "unprognostic (8.51e-2)" "unprognostic (7.74e-2)" "unprognostic (5.19e-3)" VSIG8 ENSG00000243284 "V-set and immunoglobulin domain containing 8" P0DPA2 1 159854316-159862657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 25.6" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 143.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.5" "Kidney - Podocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023219 Uncertain NA NA 650000 "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA023219: AB_1845635" "unprognostic (8.66e-3)" "unprognostic (2.17e-1)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (4.50e-3)" "unprognostic (1.15e-2)" "unprognostic (9.26e-2)" "unprognostic (6.28e-2)" "unprognostic (1.68e-2)" "unprognostic (2.79e-1)" "unprognostic (2.93e-3)" "unprognostic (9.32e-2)" "unprognostic (7.94e-7)" "unprognostic (1.72e-2)" "unprognostic (4.25e-1)" "unprognostic (1.81e-3)" "unprognostic (1.99e-1)" ZBED2 MGC10796 ENSG00000177494 "Zinc finger BED-type containing 2" Q9BTP6 3 111592900-111595346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 47.6;thyroid gland: 71.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 72.4;Suprabasal keratinocytes: 36.2" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 64.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" HPA029786 Approved "Nuclear bodies,Mitochondria,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 3: Suprabasal keratinocytes - Cornification" "Mitochondria, Cytosol" "Nuclear bodies" "HPA029786: AB_10601028" "unprognostic (7.31e-3)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-3)" "unprognostic (3.49e-1)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.83e-4)" "unprognostic (2.59e-1)" "unprognostic (1.47e-6)" "unprognostic (3.81e-2)" "unprognostic (4.34e-1)" "unprognostic (4.69e-2)" "unprognostic (3.29e-2)" ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 48.8;Basal prostatic cells: 76.4;Squamous epithelial cells: 81.7;Suprabasal keratinocytes: 160.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 3: Suprabasal keratinocytes - Cornification" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" ZNF770 "FLJ20582, PRO1914" ENSG00000198146 "Zinc finger protein 770" Q6IQ21 15 34978341-34988287 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 136.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024518 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 45: Non-specific - Cell proliferation" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA024518: AB_1859449" "unprognostic (1.04e-1)" "unprognostic (1.60e-2)" "unprognostic (1.75e-2)" "unprognostic (2.79e-1)" "unprognostic (2.32e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-1)" "unprognostic (6.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-3)" "unprognostic (4.24e-2)" "unprognostic (2.09e-3)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (5.06e-2)" "unprognostic (2.10e-3)"