Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABTB1 "BPOZ, Btb3, BTBD21, EF1ABP" ENSG00000114626 "Ankyrin repeat and BTB domain containing 1" Q969K4 3 127672935-127680926 "Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 822.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035022, HPA035023" Uncertain Supported Nucleoli,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 33: Macrophages - Degranulation" Cytosol Nucleoli "HPA035022: AB_10669998, HPA035023: AB_10602104" "unprognostic (6.76e-2)" "unprognostic (9.18e-3)" "unprognostic (2.11e-2)" "unprognostic (6.34e-2)" "unprognostic (6.51e-2)" "unprognostic (2.00e-3)" "unprognostic (4.43e-2)" "unprognostic (2.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.48e-3)" "unprognostic (4.55e-3)" "unprognostic (2.86e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (2.88e-1)" "unprognostic (1.81e-2)" "unprognostic (3.98e-2)" "unprognostic (7.92e-3)" AC008763.3 ENSG00000269711 "Novel protein" 19 7678501-7682854 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "bone marrow: 22.6;intestine: 7.7;lung: 18.3;lymphoid tissue: 12.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "classical monocyte: 202.7;neutrophil: 90.1" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 5 "Leukemia: 4.5" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" AC099489.1 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527245 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Langerhans cells: 6.5;Mucus glandular cells: 14.1;Oligodendrocyte precursor cells: 5.8;Salivary duct cells: 5.1;Skeletal myocytes: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cancer enhanced" "Detected in some" "Myeloma: 3.5" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "HPA042154: AB_2677877" "unprognostic (4.69e-2)" "unprognostic (3.80e-2)" "unprognostic (7.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.21e-3)" "unprognostic (7.91e-2)" "unprognostic (9.18e-2)" "unprognostic (6.08e-2)" "unprognostic (8.04e-2)" "unprognostic (5.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-1)" "unprognostic (3.72e-6)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (4.33e-5)" ACAP2 "CENTB2, CNT-B2, KIAA0041" ENSG00000114331 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 2" Q15057 3 195274745-195443044 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 215.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034807, HPA034808" Supported Approved Endosomes NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 43: Non-specific - Mitochondria" "Cluster 33: Macrophages - Degranulation" Endosomes "HPA034807: AB_10669896, HPA034808: AB_10673103" "unprognostic (9.13e-2)" "unprognostic (1.75e-3)" "unprognostic (7.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.90e-2)" "unprognostic (5.64e-2)" "unprognostic (3.08e-3)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.57e-1)" "unprognostic (5.49e-2)" "unprognostic (2.36e-2)" "unprognostic (1.01e-2)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (3.77e-2)" "unprognostic (8.54e-2)" ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in all" "Early spermatids: 236.4;Hepatocytes: 1012.8;Late spermatids: 534.6;monocytes: 273.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" ACTR2 ARP2 ENSG00000138071 "Actin related protein 2" P61160 2 65227788-65271253 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 611.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005083, HPA015050" Approved Approved Cytosol NA NA 35000000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB005083: AB_2221848, HPA015050: AB_1844556" "unprognostic (2.23e-1)" "unprognostic (1.15e-3)" "unprognostic (3.89e-2)" "unprognostic (2.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (3.88e-2)" "unprognostic (3.16e-2)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (8.59e-2)" "unprognostic (2.36e-3)" "unprognostic (3.18e-2)" "unprognostic (4.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.03e-2)" ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "dendritic cells: 118.7;Hofbauer cells: 93.0;Kupffer cells: 181.0;Langerhans cells: 134.4;Macrophages: 151.5;monocytes: 178.6;Schwann cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 14.0;lymphoma: 7.1;Myeloma: 20.3;Rhabdoid: 7.6;testis cancer: 19.1" "Lung - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 14.8" "Cell type enhanced" "Detected in some" "Kupffer cells: 24.9;Macrophages: 12.4;monocytes: 65.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 166.4;eosinophil: 324.9" "Group enriched" "Detected in many" 18 "granulocytes: 324.9;monocytes: 105.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.4" "Cell type enhanced" "Detected in many" "granulocytes: 52.9;Hofbauer cells: 30.3;Kupffer cells: 68.8;Macrophages: 66.3;monocytes: 182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.0;eosinophil: 74.7;intermediate monocyte: 46.9;neutrophil: 55.7;non-classical monocyte: 89.9" "Group enriched" "Detected in many" 9 "granulocytes: 74.7;monocytes: 89.9" "Cancer enhanced" "Detected in many" "Leukemia: 7.4" "Lung - Neutrophil_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 147.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 4.1;Erythroid cells: 7.0;NK-cells: 2.9;Pancreatic endocrine cells: 3.4;Serous glandular cells: 2.9;T-cells: 3.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebral cortex: 10.6" "Immune cell enhanced" "Detected in some" "eosinophil: 142.3;neutrophil: 169.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 169.8" "Group enriched" "Detected in some" 7 "Leukemia: 2.3;lymphoma: 1.9" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 1200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" AGO1 "EIF2C1, hAGO1" ENSG00000092847 "Argonaute RISC component 1" Q9UL18 1 35869808-35930532 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067849 Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Cytoplasmic bodies" Cytosol "HPA067849: " "unprognostic (2.35e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (8.66e-3)" "unprognostic (1.20e-1)" "unprognostic (3.71e-2)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.61e-2)" "unprognostic (6.08e-2)" "unprognostic (1.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.60e-4)" "unprognostic (7.52e-2)" "unprognostic (1.74e-1)" "unprognostic (7.57e-2)" "unprognostic (5.77e-3)" AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 59.7;Inhibitory neurons: 70.4;Microglial cells: 62.0;Oligodendrocyte precursor cells: 83.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "prognostic favorable (5.70e-5)" "unprognostic (3.92e-3)" "unprognostic (3.99e-3)" "unprognostic (2.32e-2)" "unprognostic (9.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-3)" "unprognostic (4.91e-3)" "unprognostic (4.96e-2)" "unprognostic (2.58e-1)" "unprognostic (3.96e-1)" "unprognostic (1.58e-2)" AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 181.6;Hofbauer cells: 164.9;Kupffer cells: 173.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 7 "Hofbauer cells: 2459.1;Kupffer cells: 1902.8;Langerhans cells: 1685.0;Macrophages: 1457.6;monocytes: 3085.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Cancer enriched" "Detected in some" 28 "Leukemia: 77.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442621 "Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 71.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favorable (1.17e-4)" ANKHD1-EIF4EBP3 MASK-BP3 ENSG00000254996 "ANKHD1-EIF4EBP3 readthrough" 5 140401908-140549569 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 6.0;Inhibitory neurons: 5.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA008718 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 57: Non-specific - Translation" "Cluster 33: Macrophages - Degranulation" "HPA008718: AB_1078162" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (6.17e-3)" "unprognostic (4.10e-3)" "unprognostic (4.84e-2)" "unprognostic (8.79e-2)" "unprognostic (2.82e-3)" "unprognostic (4.69e-2)" "unprognostic (1.09e-1)" "unprognostic (1.88e-2)" "unprognostic (1.69e-3)" "unprognostic (4.53e-1)" "unprognostic (8.92e-3)" "unprognostic (2.92e-2)" "unprognostic (3.27e-1)" "unprognostic (4.33e-3)" "unprognostic (2.60e-2)" ANKRD34B DP58 ENSG00000189127 "Ankyrin repeat domain 34B" A5PLL1 5 80556755-80570280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "brain: 40.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Hofbauer cells: 1.1;Inhibitory neurons: 5.8;Kupffer cells: 2.4" "Cancer enhanced" "Detected in some" "prostate cancer: 2.3" "Region enhanced" "Detected in many" "thalamus: 40.7" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Group enriched" "Detected in some" 4 "ovarian cancer: 4.3;Uterine cancer: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043327 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Mitochondria" Cytosol "HPA043327: AB_10794180" "unprognostic (1.05e-1)" "unprognostic (4.16e-6)" "unprognostic (2.07e-4)" "unprognostic (1.05e-1)" "unprognostic (3.03e-1)" "unprognostic (8.25e-4)" "unprognostic (6.44e-2)" "unprognostic (1.80e-1)" "unprognostic (9.41e-2)" "unprognostic (6.52e-3)" "unprognostic (1.93e-1)" "unprognostic (4.28e-2)" "unprognostic (1.02e-1)" "unprognostic (2.33e-1)" "unprognostic (2.94e-2)" AP000295.1 ENSG00000249624 "Novel protein" 21 33229901-33297160 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 5.9" "Group enriched" "Detected in many" 6 "granulocytes: 5.9;monocytes: 2.8" "Low cancer specificity" "Detected in single" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.39e-1)" "unprognostic (8.87e-2)" "unprognostic (4.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.62e-1)" "unprognostic (3.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.12e-1)" "unprognostic (5.46e-2)" "unprognostic (2.92e-2)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (1.53e-2)" "unprognostic (2.33e-2)" AP001781.2 ENSG00000258529 "Novel protein" 11 111786286-111879425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" HPA038575 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" "HPA038575: AB_10672718" AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 434.4;Kupffer cells: 369.1;Langerhans cells: 721.3;Macrophages: 351.2;monocytes: 557.3;Schwann cells: 370.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cancer enhanced" "Detected in all" "skin cancer: 169.9" "Breast - Endothelial cells, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 91.1;dendritic cells: 126.6;Kupffer cells: 121.2;Macrophages: 121.4;Microglial cells: 371.2;monocytes: 108.2;NK-cells: 121.7;T-cells: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Kidney cancer: 37.1;Leukemia: 69.8;lymphoma: 80.6;Myeloma: 23.1" "Breast - Adipocytes (Breast), Colon - Macrophages, Heart muscle - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 93.9;lymphoid tissue: 48.3;urinary bladder: 24.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 92.8;Hofbauer cells: 134.5;Kupffer cells: 76.9;Langerhans cells: 47.0;Macrophages: 48.9;monocytes: 172.9;Serous glandular cells: 82.1;Squamous epithelial cells: 56.1;Suprabasal keratinocytes: 122.3" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1014.5" "Lineage enriched" "Detected in many" 8 "monocytes: 1014.5" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 8.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 702.7" "Cell type enhanced" "Detected in some" "Hepatocytes: 281.2;Hofbauer cells: 72.6;Kupffer cells: 88.6;Macrophages: 67.8;monocytes: 174.8" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1161.4" "Lineage enriched" "Detected in many" 20 "granulocytes: 1161.4" "Cancer enriched" "Detected in some" 7 "lymphoma: 10.1" "Adipose subcutaneous - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA074762, CAB075684" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" ARHGAP27 "CAMGAP1, FLJ43547, SH3D20, SH3P20" ENSG00000159314 "Rho GTPase activating protein 27" Q6ZUM4 17 45393902-45434421 "Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.4;Kupffer cells: 67.5;Paneth cells: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023919, HPA053053" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "HPA023919: AB_2059402, HPA053053: AB_2682027" "unprognostic (9.80e-2)" "unprognostic (1.36e-1)" "unprognostic (7.34e-2)" "unprognostic (4.89e-3)" "unprognostic (4.66e-1)" "unprognostic (2.69e-2)" "unprognostic (7.69e-2)" "unprognostic (6.89e-2)" "unprognostic (2.26e-1)" "unprognostic (2.33e-1)" "unprognostic (1.49e-2)" "unprognostic (1.96e-3)" "unprognostic (5.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.21e-4)" ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.0;Kupffer cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 313.9;Kupffer cells: 225.1;Langerhans cells: 205.6;Macrophages: 224.2;monocytes: 307.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Plasma membrane" Cytosol "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" ATG16L2 "ATG16B, FLJ00012, WDR80" ENSG00000168010 "Autophagy related 16 like 2" Q8NAA4 11 72814406-72843674 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 136.8;lymphoid tissue: 129.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 55.4;monocytes: 51.7;Paneth cells: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 45.4;neutrophil: 59.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045444, HPA050312" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA045444: AB_2679324, HPA050312: AB_2681082" "unprognostic (7.20e-3)" "unprognostic (1.16e-1)" "unprognostic (1.54e-1)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" "prognostic favorable (7.06e-4)" "unprognostic (2.49e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (4.38e-2)" "unprognostic (1.08e-1)" "unprognostic (4.83e-2)" ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: Non-specific - Mitochondria" "Cluster 33: Macrophages - Degranulation" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 5.3;Endometrial ciliated cells: 10.7;Erythroid cells: 6.5;Hofbauer cells: 4.9;Kupffer cells: 5.2;Respiratory ciliated cells: 7.1;Spermatogonia: 7.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cancer enriched" "Detected in single" 43 "Leukemia: 40.5" "Liver - Erythroid cells, Lung - Neutrophil_1" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" BECN1 "ATG6, VPS30" ENSG00000126581 "Beclin 1" Q14457 17 42810134-42833350 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Autophagy, Cell cycle, Cell division, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003949, CAB010143, HPA028949" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" Cytosol "Nuclear bodies" "CAB010143: AB_626746, HPA003949: , HPA028949: AB_2672839" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (9.97e-2)" "unprognostic (3.80e-3)" "unprognostic (1.46e-1)" "unprognostic (2.01e-2)" "unprognostic (5.16e-3)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.59e-2)" "unprognostic (4.33e-2)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (1.02e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-2)" BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.3;brain: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.8;Oligodendrocytes: 40.6" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.6" "Cancer enhanced" "Detected in many" "skin cancer: 20.4" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 33: Macrophages - Degranulation" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 62.3;Kupffer cells: 49.9;Macrophages: 36.0;monocytes: 34.7;Proximal enterocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" C15orf39 "DKFZP434H132, FLJ46337" ENSG00000167173 "Chromosome 15 open reading frame 39" Q6ZRI6 15 75195643-75212169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.9;testis: 73.7" "Cell type enhanced" "Detected in many" "Early spermatids: 54.0;Late spermatids: 61.4;monocytes: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.0;granulocytes: 23.5;monocytes: 16.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039961, HPA041907" Enhanced Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA039961: AB_10673024, HPA041907: AB_2677736" "unprognostic (3.53e-2)" "unprognostic (1.66e-1)" "unprognostic (4.57e-2)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.00e-1)" "unprognostic (2.20e-2)" "unprognostic (3.46e-2)" "prognostic favorable (7.94e-4)" "unprognostic (3.38e-2)" "unprognostic (2.74e-1)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (2.95e-1)" "unprognostic (1.14e-1)" C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 98.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 64.7;Kupffer cells: 114.6;Macrophages: 50.5;monocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.3;eosinophil: 169.4;intermediate monocyte: 312.5;myeloid DC: 162.2;neutrophil: 230.1;non-classical monocyte: 392.8" "Group enriched" "Detected in all" 20 "dendritic cells: 162.2;granulocytes: 230.1;monocytes: 392.8" "Group enriched" "Detected in some" 4 "Leukemia: 11.1;lymphoma: 5.5;Myeloma: 5.9" "Kidney - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: AB_10603448, HPA055027: " "unprognostic (6.65e-3)" "prognostic favorable (2.43e-4)" "unprognostic (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-3)" "unprognostic (3.56e-1)" "unprognostic (8.27e-2)" "unprognostic (5.60e-2)" "unprognostic (6.02e-2)" "unprognostic (9.74e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.75e-7)" "unprognostic (2.31e-1)" "unprognostic (4.00e-2)" "unprognostic (1.03e-2)" "unprognostic (2.11e-2)" CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enhanced" "Detected in many" "B-cells: 66.5;Hofbauer cells: 70.7;Kupffer cells: 100.5;Macrophages: 83.0;monocytes: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 16.3" "Liver - Kupffer cells, Stomach - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 85.5;monocytes: 98.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 280.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 280.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 13.4;Hofbauer cells: 25.7;Kupffer cells: 17.0;Langerhans cells: 16.8;Macrophages: 22.3;monocytes: 31.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 20.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025443-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 126.0;lymphoid tissue: 91.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 149.2;Langerhans cells: 152.7;Macrophages: 120.8;monocytes: 261.6;Proximal enterocytes: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Region enhanced" "Detected in all" "olfactory bulb: 18.4" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 61.4;Kupffer cells: 82.3;Langerhans cells: 16.6;Macrophages: 24.2;monocytes: 15.3;Plasma cells: 35.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 34.2" "Breast - Plasma cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 51: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 18.2;liver: 15.3;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 4 "B-cells: 20.6;Hofbauer cells: 30.9;Kupffer cells: 55.9;Macrophages: 35.8;monocytes: 40.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 139.0;intermediate monocyte: 63.8;myeloid DC: 139.3" "Group enriched" "Detected in many" 8 "dendritic cells: 139.3;monocytes: 139.0" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;lymphoma: 2.0" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "Hofbauer cells: 43.1;Kupffer cells: 12.5;Langerhans cells: 16.2;Macrophages: 27.4;monocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 5.3;lymphoma: 5.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" CD300E "CD300LE, CLM2, IREM2" ENSG00000186407 "CD300e molecule" Q496F6 17 74609885-74623738 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.1;lymphoid tissue: 37.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 50.8;Kupffer cells: 116.5;Macrophages: 83.9;monocytes: 216.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "thalamus: 3.7" "Group enriched" "Detected in some" 6 "classical monocyte: 88.0;intermediate monocyte: 135.1;non-classical monocyte: 148.5" "Lineage enriched" "Detected in many" 7 "monocytes: 148.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Colon - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA015570 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" "HPA015570: AB_1846294" "unprognostic (1.70e-1)" "unprognostic (6.82e-2)" "unprognostic (1.76e-1)" "unprognostic (2.63e-2)" "unprognostic (1.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.68e-2)" "unprognostic (7.80e-3)" "unprognostic (4.51e-1)" "unprognostic (1.53e-1)" "unprognostic (2.69e-2)" "unprognostic (5.15e-2)" "unprognostic (4.19e-7)" "unprognostic (1.90e-2)" "unprognostic (2.00e-4)" "unprognostic (7.38e-3)" "unprognostic (1.19e-1)" CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 7.8;brain: 16.3;lymphoid tissue: 8.2" "Group enriched" "Detected in some" 15 "dendritic cells: 14.9;Hofbauer cells: 13.3;Kupffer cells: 21.3;Langerhans cells: 9.5;Macrophages: 14.8;monocytes: 11.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 16.3" "Immune cell enhanced" "Detected in many" "eosinophil: 75.9" "Group enriched" "Detected in many" 53 "dendritic cells: 25.0;granulocytes: 75.9;monocytes: 31.7" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.8" "Adipose visceral - Macrophages, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060449 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA060449: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (3.32e-1)" "unprognostic (2.49e-4)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (7.08e-2)" "unprognostic (4.01e-2)" CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 317.5;Kupffer cells: 276.3;Langerhans cells: 130.6;Macrophages: 206.1;monocytes: 167.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" CEACAM3 "CD66d, CGM1" ENSG00000170956 "CEA cell adhesion molecule 3" P40198 19 41796587-41811554 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 44.3" "Cell type enriched" "Detected in some" 14 "Paneth cells: 48.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 6 "neutrophil: 289.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 289.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - NK-cells (Lung), Stomach - Neutrophils, Thyroid - Neutrophils" HPA011041 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 33: Macrophages - Degranulation" "HPA011041: AB_1078481" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (8.09e-3)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.68e-2)" "unprognostic (8.44e-2)" "unprognostic (2.83e-1)" CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Group enriched" "Detected in some" 7 "Hofbauer cells: 9.5;Kupffer cells: 30.4;Macrophages: 22.3;monocytes: 16.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.8" "Adipose visceral - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" CEPT1 ENSG00000134255 "Choline/ethanolamine phosphotransferase 1" Q9Y6K0 1 111139627-111185104 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 38: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.47e-3)" "unprognostic (1.83e-2)" "prognostic favorable (4.96e-4)" "unprognostic (5.52e-2)" "unprognostic (1.10e-1)" "unprognostic (5.61e-2)" "unprognostic (1.54e-3)" "unprognostic (1.84e-1)" "unprognostic (9.20e-3)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "unprognostic (5.88e-2)" "unprognostic (1.27e-2)" CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in some" "Kupffer cells: 9.6;Langerhans cells: 22.1;Macrophages: 40.5;monocytes: 15.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cancer enriched" "Detected in some" 7 "Leukemia: 12.0" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" CHST15 "BRAG, GALNAC4S-6ST, KIAA0598" ENSG00000182022 "Carbohydrate sulfotransferase 15" Q7LFX5 10 124007668-124093598 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 59.6;monocytes: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 69.0" "Group enriched" "Detected in many" 11 "granulocytes: 69.0;monocytes: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017584 Approved Approved Centrosome,Cytosol NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Cytosol Centrosome "HPA017584: AB_1849437" "unprognostic (1.19e-1)" "unprognostic (2.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-2)" "unprognostic (4.12e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-2)" "unprognostic (2.40e-2)" "unprognostic (7.62e-3)" "unprognostic (7.90e-2)" "unprognostic (8.16e-2)" "prognostic unfavorable (2.22e-7)" "unprognostic (6.47e-3)" "unprognostic (7.80e-2)" "unprognostic (4.63e-3)" "unprognostic (5.26e-3)" CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 262.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 292.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "HPA040459: AB_10796456, HPA063729: AB_2685105" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (6.59e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.07e-2)" "unprognostic (4.06e-3)" "unprognostic (5.02e-2)" "unprognostic (7.16e-2)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-3)" "unprognostic (8.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-2)" CLEC12A "CD371, CLL-1, DCAL-2, MICL" ENSG00000172322 "C-type lectin domain family 12 member A" Q5QGZ9 12 9951316-9995694 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 79.9;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "granulocytes: 29.9;Hofbauer cells: 64.9;Kupffer cells: 99.4;Macrophages: 127.3;monocytes: 181.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "eosinophil: 202.6" "Group enriched" "Detected in many" 37 "dendritic cells: 72.6;granulocytes: 202.6;monocytes: 136.6" "Cancer enriched" "Detected in some" 12 "Leukemia: 21.3" "Stomach - Macrophages" "Region enriched" "Detected in single" 7 "basal ganglia: 6.2" "Not detected" "Not detected" HPA048515 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA048515: AB_2680425" "unprognostic (4.74e-2)" "unprognostic (6.06e-3)" "unprognostic (7.76e-2)" "unprognostic (6.88e-2)" "unprognostic (2.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (3.29e-1)" "unprognostic (1.44e-2)" "unprognostic (1.70e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-3)" "unprognostic (9.67e-3)" "unprognostic (7.43e-2)" "unprognostic (3.78e-2)" "prognostic favorable (9.33e-4)" CLEC4A "CD367, CLECSF6, DCIR, DDB27" ENSG00000111729 "C-type lectin domain family 4 member A" Q9UMR7 12 8123617-8138607 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 21.6;lymphoid tissue: 26.9" "Group enriched" "Detected in some" 5 "Hofbauer cells: 14.3;Kupffer cells: 37.4;Langerhans cells: 31.5;Macrophages: 35.9;monocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 226.8;classical monocyte: 331.7;intermediate monocyte: 198.1;myeloid DC: 327.4;neutrophil: 298.3;non-classical monocyte: 130.0" "Group enriched" "Detected in all" 13 "dendritic cells: 327.4;granulocytes: 298.3;monocytes: 331.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA007842 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "HPA007842: AB_1078534" "unprognostic (9.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.13e-2)" "unprognostic (2.69e-1)" "unprognostic (9.34e-2)" "unprognostic (5.49e-2)" "unprognostic (8.22e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.42e-3)" "unprognostic (1.42e-1)" "unprognostic (1.35e-2)" "unprognostic (3.05e-1)" "unprognostic (9.79e-2)" CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 64.7" "Group enriched" "Detected in some" 7 "Hofbauer cells: 8.1;Kupffer cells: 22.7;Macrophages: 10.5" "Cancer enriched" "Detected in single" 50 "testis cancer: 11.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 57.1;neutrophil: 98.7" "Group enriched" "Detected in many" 32 "granulocytes: 98.7;monocytes: 57.1" "Cancer enriched" "Detected in some" 6 "testis cancer: 9.1" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA004906: AB_1078535" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.39e-1)" "unprognostic (3.84e-2)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.81e-1)" "unprognostic (7.91e-5)" "unprognostic (1.12e-2)" "unprognostic (8.57e-2)" "unprognostic (7.89e-2)" "unprognostic (2.18e-1)" CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 40.0;Hofbauer cells: 53.7;Kupffer cells: 219.9;Macrophages: 111.5;monocytes: 111.2" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 9 "Kidney cancer: 34.2;ovarian cancer: 11.5" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.2" "Group enriched" "Detected in some" 4 "monocytes: 19.2;Rod photoreceptor cells: 9.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cancer enhanced" "Detected in some" "lymphoma: 5.0" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "HPA056101: " "unprognostic (8.14e-3)" "unprognostic (3.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (4.91e-2)" "unprognostic (5.41e-2)" "unprognostic (3.66e-2)" "unprognostic (2.07e-2)" "unprognostic (9.29e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-2)" "unprognostic (9.59e-2)" "unprognostic (2.44e-1)" CNPY3 "CAG4A, TNRC5" ENSG00000137161 "Canopy FGF signaling regulator 3" Q9BT09 6 42929192-42939294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" Chaperone "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 274.1;Extravillous trophoblasts: 206.1;Hofbauer cells: 310.8;Kupffer cells: 202.2;monocytes: 213.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016560 Uncertain "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "HPA016560: AB_1858173" "unprognostic (5.26e-3)" "unprognostic (6.63e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (8.15e-2)" "unprognostic (3.12e-1)" "unprognostic (1.79e-1)" "unprognostic (5.70e-3)" "unprognostic (5.11e-2)" "unprognostic (4.77e-2)" "unprognostic (1.94e-2)" "unprognostic (2.26e-3)" "unprognostic (4.54e-2)" "prognostic unfavorable (9.85e-6)" "unprognostic (2.34e-1)" "unprognostic (1.93e-2)" "unprognostic (2.21e-2)" "unprognostic (2.98e-3)" COTL1 CLP ENSG00000103187 "Coactosin like F-actin binding protein 1" Q14019 16 84565596-84618078 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Chaperone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 273.2;lymphoid tissue: 374.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1669.7;Hofbauer cells: 873.7;Kupffer cells: 933.7;Langerhans cells: 1317.7;Macrophages: 861.0;monocytes: 2850.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 2441.1;eosinophil: 3418.8;intermediate monocyte: 4072.1;myeloid DC: 2395.7;neutrophil: 1758.0;non-classical monocyte: 4579.3" "Group enriched" "Detected in all" 5 "dendritic cells: 2395.7;granulocytes: 3418.8;monocytes: 4579.3" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "HPA008918, CAB062328" Enhanced Supported Cytosol NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB062328: AB_2084785, HPA008918: AB_2668176" "unprognostic (2.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.27e-2)" "unprognostic (2.38e-1)" "unprognostic (3.21e-3)" "unprognostic (8.95e-2)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (7.70e-2)" "unprognostic (5.99e-2)" "unprognostic (5.43e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (5.48e-2)" "unprognostic (7.73e-2)" "unprognostic (3.35e-3)" CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 104.5;monocytes: 171.4;Syncytiotrophoblasts: 155.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 674.2" "Group enriched" "Detected in all" 28 "dendritic cells: 168.5;granulocytes: 674.2;monocytes: 320.8" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Group enriched" "Detected in some" 4 "B-cells: 41.1;Erythroid cells: 17.2;Hofbauer cells: 17.1;Kupffer cells: 35.6;Macrophages: 45.8;monocytes: 18.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 7 "Leukemia: 3.5;lymphoma: 1.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Podocytes, Lung - Neutrophil_2, Prostate - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" CSF2RB "betaGMR, CD131, IL3RB, IL5RB" ENSG00000100368 "Colony stimulating factor 2 receptor subunit beta" P32927 22 36913628-36940439 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.5;lymphoid tissue: 65.5" "Cell type enhanced" "Detected in many" "dendritic cells: 117.3;Extravillous trophoblasts: 43.6;granulocytes: 81.5;Kupffer cells: 41.4;Langerhans cells: 74.7;Late spermatids: 41.5;Macrophages: 35.8;Plasma cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 238.1;neutrophil: 76.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 238.1" "Group enriched" "Detected in some" 62 "Leukemia: 44.6;lymphoma: 18.9;Myeloma: 14.3" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078677 Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "HPA078677: AB_2732389" "unprognostic (1.67e-2)" "unprognostic (9.44e-3)" "unprognostic (1.03e-2)" "unprognostic (6.66e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.47e-5)" "unprognostic (1.86e-1)" "unprognostic (1.94e-2)" "unprognostic (4.38e-1)" "unprognostic (9.57e-2)" "unprognostic (1.33e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-3)" "unprognostic (5.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.95e-1)" "unprognostic (8.52e-2)" CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.3" "Cell type enhanced" "Detected in all" "B-cells: 130.9;Kupffer cells: 106.7;monocytes: 185.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 7 "basal ganglia: 7.4" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 370000000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 1251.0;Kupffer cells: 1985.8;Macrophages: 1477.6;monocytes: 3148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 42.8;Myeloma: 35.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 49.4;Exocrine glandular cells: 20.8;Glandular and luminal cells: 24.0;Hofbauer cells: 22.7;Langerhans cells: 29.3;Macrophages: 40.2;monocytes: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Group enriched" "Detected in many" 5 "head and neck cancer: 12.0;lymphoma: 25.2" "Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" CXCL11 "b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B" ENSG00000169248 "C-X-C motif chemokine ligand 11" O14625 4 76033682-76041415 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.7;Exocrine glandular cells: 8.8;Hofbauer cells: 2.1;Kupffer cells: 2.4;Macrophages: 3.4;monocytes: 2.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2;head and neck cancer: 13.5" "Adipose visceral - T-cells" "Region enhanced" "Detected in single" "spinal cord: 1.2" CAB009921 Uncertain "Secreted to blood" NA NA 187000 "Cluster 3: T-cells - Adaptive immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" "CAB009921: AB_2088137" "unprognostic (2.00e-1)" "unprognostic (3.62e-1)" "unprognostic (6.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.95e-2)" "unprognostic (5.85e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.31e-7)" "prognostic unfavorable (8.18e-5)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.29e-6)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (4.48e-2)" "unprognostic (5.32e-2)" CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Group enriched" "Detected in some" 5 "NK-cells: 10.0;Serous glandular cells: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "NK-cells: 31.3;Serous glandular cells: 15.1;Squamous epithelial cells: 13.8;Suprabasal keratinocytes: 16.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Cancer enriched" "Detected in single" 6 "Leukemia: 5.6" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "dendritic cells: 334.1;Hofbauer cells: 226.4;Kupffer cells: 358.4;Macrophages: 451.2;monocytes: 516.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Cancer enhanced" "Detected in some" "Leukemia: 17.9;lymphoma: 28.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271468-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.6" "Cell type enhanced" "Detected in many" "Adipocytes: 27.6;B-cells: 62.5;dendritic cells: 69.2;granulocytes: 37.0;Hofbauer cells: 36.4;Macrophages: 32.7;monocytes: 43.3;Plasma cells: 41.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 85.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "Leukemia: 7.3;lymphoma: 2.7;Myeloma: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010546 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA010546: AB_1078268" "unprognostic (9.48e-2)" "unprognostic (6.01e-5)" "unprognostic (4.72e-3)" "unprognostic (3.04e-1)" "unprognostic (6.30e-2)" "unprognostic (2.80e-3)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (4.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-4)" "unprognostic (5.82e-2)" "unprognostic (3.56e-2)" "unprognostic (9.87e-2)" "unprognostic (8.94e-2)" DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" "Nuclear speckles" "HPA045940: AB_2679506" "unprognostic (1.00e-2)" "unprognostic (3.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "unprognostic (5.47e-2)" "unprognostic (4.75e-3)" "unprognostic (8.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.42e-1)" "prognostic favorable (3.94e-9)" "unprognostic (1.79e-1)" "unprognostic (2.40e-1)" "unprognostic (3.04e-1)" "unprognostic (5.84e-3)" DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113022195 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 57: Non-specific - Translation" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: AB_2683500" "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavorable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavorable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999195 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 872.0" "Cell type enriched" "Detected in single" 8 "Kupffer cells: 3.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Neutrophil_1" HPA052517 Supported "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 39: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" "HPA052517: AB_2681860" DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enriched" "Detected in some" 20 "Kupffer cells: 21.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cancer enriched" "Detected in single" 21 "Leukemia: 2.1" "Liver - Erythroid cells, Lung - Neutrophil_1" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA051266: AB_2681414" DENND10 FAM45A ENSG00000119979 "DENN domain containing 10" Q8TCE6 10 119104086-119137984 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 147.4;Proximal tubular cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061569 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA061569: " "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "unprognostic (1.88e-2)" "unprognostic (2.13e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-2)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" "unprognostic (6.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.20e-2)" DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 96.5;Microglial cells: 77.5;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cancer enhanced" "Detected in all" "Leukemia: 68.5" "Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" DENND4B KIAA0476 ENSG00000198837 "DENN domain containing 4B" O75064 1 153929501-153946718 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040188, HPA071133" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 18: Non-specific - RNA binding" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Golgi apparatus" "HPA040188: AB_10671168, HPA071133: AB_2732173" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (1.59e-2)" "unprognostic (9.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-3)" "prognostic unfavorable (4.14e-4)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.18e-5)" "unprognostic (2.21e-1)" "prognostic unfavorable (9.27e-9)" "unprognostic (4.24e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.56e-3)" DMXL2 "DFNA71, KIAA0856, RC3" ENSG00000104093 "Dmx like 2" Q8TDJ6 15 51447711-51622833 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Diabetes mellitus, Disease variant, Epilepsy, Hypogonadotropic hypogonadism, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 136.9;Inhibitory neurons: 120.1;Kupffer cells: 84.4;Macrophages: 102.3;monocytes: 120.0;Oligodendrocyte precursor cells: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 2.8;intermediate monocyte: 2.2;neutrophil: 2.2;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 4 "granulocytes: 2.2;monocytes: 2.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039375 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA039375: AB_10673610" "unprognostic (5.66e-2)" "unprognostic (9.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-2)" "unprognostic (8.38e-2)" "unprognostic (3.39e-1)" "unprognostic (2.32e-1)" "unprognostic (3.67e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (1.09e-1)" "unprognostic (1.67e-1)" "unprognostic (8.60e-3)" "unprognostic (2.70e-2)" DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.0;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "B-cells: 114.5;Macrophages: 115.6;Microglial cells: 493.5;monocytes: 156.9;T-cells: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 53.0;granulocytes: 173.6;monocytes: 84.2" "Group enriched" "Detected in many" 5 "Leukemia: 49.3;lymphoma: 38.8;Myeloma: 19.4" "Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA003219, HPA073349" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA003218: AB_1078695, HPA003219: , HPA073349: " "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-2)" "unprognostic (7.55e-3)" "unprognostic (3.31e-1)" "unprognostic (6.28e-3)" "unprognostic (1.79e-1)" "unprognostic (8.12e-2)" "unprognostic (2.72e-2)" "unprognostic (6.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.91e-1)" "prognostic favorable (6.89e-6)" DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 6 "B-cells: 31.5;granulocytes: 20.6;Hofbauer cells: 58.7;Kupffer cells: 55.3;Macrophages: 38.7;monocytes: 44.6;Plasma cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cancer enhanced" "Detected in all" "Leukemia: 72.7;lymphoma: 107.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 43.7;Kupffer cells: 39.4;Langerhans cells: 27.6;Macrophages: 32.8;monocytes: 57.2;Syncytiotrophoblasts: 68.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 410.0;eosinophil: 841.1;neutrophil: 358.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 841.1" "Cancer enhanced" "Detected in some" "Leukemia: 6.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.3" HPA035644 Approved NA NA 330000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: Non-specific - Protein binding" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" EIF4E3 MGC39820 ENSG00000163412 "Eukaryotic translation initiation factor 4E family member 3" Q8N5X7 3 71675414-71754773 "Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 14.7" "Group enriched" "Detected in many" 7 "granulocytes: 14.7;monocytes: 4.2;T-cells: 5.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058649, HPA076465" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoli fibrillar center" "HPA058649: AB_2683785, HPA076465: " "unprognostic (3.16e-3)" "unprognostic (7.60e-3)" "unprognostic (4.28e-2)" "unprognostic (1.67e-2)" "unprognostic (1.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.31e-2)" "prognostic favorable (6.63e-4)" "unprognostic (3.10e-2)" "prognostic favorable (4.64e-5)" "unprognostic (3.16e-2)" "unprognostic (4.58e-2)" "prognostic favorable (6.99e-5)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.64e-2)" "unprognostic (1.83e-2)" ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: AB_1853023" "unprognostic (7.19e-2)" "unprognostic (1.38e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (5.11e-2)" "unprognostic (1.27e-1)" "unprognostic (8.63e-2)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" EVI2A "EVDA, EVI2" ENSG00000126860 "Ecotropic viral integration site 2A" P22794 17 31316410-31321749 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;lymphoid tissue: 105.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 187.4;Kupffer cells: 232.9;Langerhans cells: 134.3;Macrophages: 126.9;monocytes: 110.1;NK-cells: 98.3;Oligodendrocytes: 206.6;T-cells: 107.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.3;Myeloma: 64.3" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "HPA045033, HPA057051" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nuclear bodies" "HPA045033: AB_2679191, HPA057051: AB_2683321" "unprognostic (7.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" "unprognostic (8.49e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.55e-4)" "unprognostic (1.90e-1)" "unprognostic (3.54e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.63e-6)" "unprognostic (7.64e-2)" "unprognostic (4.95e-2)" "unprognostic (5.87e-2)" "unprognostic (2.90e-2)" EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 224.5;Hofbauer cells: 198.7;Kupffer cells: 412.7;Langerhans cells: 191.3;Macrophages: 287.7;monocytes: 451.6;Schwann cells: 148.1;T-cells: 146.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Group enriched" "Detected in many" 11 "Leukemia: 48.2;lymphoma: 36.1;Myeloma: 61.1" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Neutrophil_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" FAM126B "HYCC2, MGC39518" ENSG00000155744 "Family with sequence similarity 126 member B" Q8IXS8 2 200973718-201071671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 4 "neutrophil: 25.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036166, HPA036167, HPA067307" Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 51: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Cell Junctions" Nucleoplasm "HPA036166: AB_10696651, HPA036167: AB_2674982, HPA067307: AB_2685821" "unprognostic (7.47e-3)" "unprognostic (5.54e-2)" "unprognostic (2.52e-1)" "unprognostic (9.08e-2)" "unprognostic (8.96e-2)" "unprognostic (3.01e-3)" "unprognostic (1.11e-2)" "unprognostic (2.61e-3)" "unprognostic (1.34e-1)" "unprognostic (1.48e-2)" "unprognostic (1.79e-2)" "unprognostic (1.90e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 407.0" "Group enriched" "Detected in all" 5 "dendritic cells: 108.2;granulocytes: 407.0;monocytes: 225.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" "HPA002484: " "unprognostic (1.53e-1)" "unprognostic (8.08e-2)" "unprognostic (6.34e-3)" "unprognostic (1.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (2.18e-2)" "unprognostic (6.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "unprognostic (3.70e-2)" "unprognostic (5.14e-2)" "prognostic favorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-3)" "unprognostic (6.18e-2)" FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 4 "Kupffer cells: 25.6;Macrophages: 17.5;monocytes: 25.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 73.8;Kupffer cells: 33.9;Macrophages: 24.9;Microglial cells: 10.9;monocytes: 12.2" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Cancer enriched" "Detected in single" 14 "Leukemia: 7.3" "Adipose visceral - Macrophages, Kidney - Macrophages, Prostate - Macrophages" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" FCGR3B "CD16, CD16b, FCG3, FCGR3" ENSG00000162747 "Fc fragment of IgG receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.6;lymphoid tissue: 82.0" "Cell type enriched" "Detected in some" 5 "Serous glandular cells: 22.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.7" "Immune cell enriched" "Detected in many" 79 "neutrophil: 7208.7" "Lineage enriched" "Detected in many" 79 "granulocytes: 7208.7" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 158.9;lung: 46.2;lymphoid tissue: 96.3" "Group enriched" "Detected in many" 8 "Hofbauer cells: 767.1;Kupffer cells: 937.2;Macrophages: 509.8;monocytes: 1153.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "classical monocyte: 1699.8;intermediate monocyte: 1195.1" "Lineage enhanced" "Detected in all" "monocytes: 1699.8" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.2" "Adipose visceral - Neutrophils, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" NA NA 1060000000 36000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB016760: , HPA000685: AB_1078840, HPA001295: AB_1078842" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-3)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.62e-3)" "unprognostic (3.66e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.59e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.28e-1)" FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 33.6;Hofbauer cells: 22.0;Intestinal goblet cells: 15.6;Macrophages: 11.6;monocytes: 42.1" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.1;prostate cancer: 3.0" "Breast - Endothelial cells, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 33: Macrophages - Degranulation" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 15.5;granulocytes: 3.1;Macrophages: 7.0;monocytes: 14.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" "Breast - Endothelial cells" HPA044681 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 33: Macrophages - Degranulation" "HPA044681: AB_2679043" "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 66.4;dendritic cells: 58.3;Kupffer cells: 85.5;Langerhans cells: 53.1;Macrophages: 56.6;Microglial cells: 42.0;monocytes: 117.4;Schwann cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Group enriched" "Detected in some" 6 "Leukemia: 2.8;lymphoma: 9.5;Myeloma: 3.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Group enriched" "Detected in many" 4 "Hofbauer cells: 119.3;Kupffer cells: 281.5;Langerhans cells: 80.3;Macrophages: 146.4;monocytes: 313.7;NK-cells: 138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 85 "Leukemia: 19.7;lymphoma: 37.8;Myeloma: 19.7" "Adipose subcutaneous - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" FOLR3 "FR-G, FRγ" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 98.7;lymphoid tissue: 28.4" "Cell type enriched" "Detected in some" 10 "Distal tubular cells: 391.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 330.8;neutrophil: 492.8" "Group enriched" "Detected in many" 11 "granulocytes: 492.8;monocytes: 330.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 12.2;Sarcoma: 6.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils" "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.47e-2)" "unprognostic (6.26e-3)" "unprognostic (1.94e-2)" "unprognostic (8.72e-3)" "unprognostic (6.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.72e-1)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (7.35e-2)" "unprognostic (7.90e-2)" "unprognostic (8.39e-2)" "unprognostic (9.99e-4)" "unprognostic (1.96e-1)" "unprognostic (2.03e-6)" "unprognostic (4.17e-1)" FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 10 "Hofbauer cells: 209.6;Kupffer cells: 392.0;Macrophages: 159.5;monocytes: 470.0" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Low cancer specificity" "Detected in many" "Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Skin - Macrophages" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enriched" "Detected in some" 9 "monocytes: 410.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.7;Leukemia: 2.7;liver cancer: 2.2" "Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Neutrophils" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.3" "Cancer enriched" "Detected in all" 4 "testis cancer: 70.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.2" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Mitochondria "HPA049763: AB_2680868" "unprognostic (4.93e-2)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (4.04e-3)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.17e-3)" "unprognostic (2.60e-1)" "unprognostic (8.02e-2)" "unprognostic (4.60e-2)" "unprognostic (3.25e-2)" "prognostic favorable (2.55e-4)" "unprognostic (7.87e-3)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.08e-2)" GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 206.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 80.7;Endothelial cells: 86.5;Granulosa cells: 127.0;Kupffer cells: 128.0;Macrophages: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.6;intermediate monocyte: 28.8;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 59.7" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in many" "Early spermatids: 242.5;Hofbauer cells: 146.5;Kupffer cells: 248.4;Macrophages: 157.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 41: Non-specific - Cilium assembly" "Cluster 33: Macrophages - Degranulation" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" GGA3 KIAA0154 ENSG00000125447 "Golgi associated, gamma adaptin ear containing, ARF binding protein 3" Q9NZ52 17 75236599-75262363 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022945, HPA024645" Approved Supported "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "HPA022945: AB_1849639, HPA024645: AB_2671629" "unprognostic (9.16e-2)" "unprognostic (8.89e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.26e-4)" "unprognostic (1.20e-1)" "unprognostic (4.60e-3)" "prognostic unfavorable (2.77e-6)" "unprognostic (6.33e-2)" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (4.63e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (3.41e-4)" "unprognostic (1.27e-1)" "unprognostic (2.99e-3)" "unprognostic (1.28e-2)" "unprognostic (9.68e-3)" GIT2 "KIAA0148, PKL" ENSG00000139436 "GIT ArfGAP 2" Q14161 12 109929802-109996389 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004681 Approved Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Microtubules "CAB004681: AB_425820" "unprognostic (1.07e-1)" "unprognostic (2.61e-1)" "unprognostic (3.67e-3)" "unprognostic (3.44e-2)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-2)" "unprognostic (3.13e-1)" "unprognostic (3.18e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.90e-1)" "unprognostic (1.37e-1)" "unprognostic (8.71e-2)" "unprognostic (2.41e-2)" GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 317.0;Extravillous trophoblasts: 476.9;Hofbauer cells: 311.6;Kupffer cells: 256.4;Langerhans cells: 492.0;Macrophages: 270.4;monocytes: 260.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" GLT1D1 FLJ31978 ENSG00000151948 "Glycosyltransferase 1 domain containing 1" Q96MS3 12 128853427-128984968 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;liver: 27.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 15.5;dendritic cells: 30.2;Excitatory neurons: 37.0;Inhibitory neurons: 29.5;Kupffer cells: 21.3;Late spermatids: 40.4;Oligodendrocyte precursor cells: 33.2" "Group enriched" "Detected in some" 6 "liver cancer: 6.2;testis cancer: 2.6;thyroid cancer: 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.4" "Cancer enhanced" "Detected in some" "Leukemia: 3.3" "Adipose visceral - Neutrophils, Colon - Colon enteroendocrine cells, Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039051, HPA039052" Enhanced Cytosol "Secreted to blood" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA039051: AB_10673299, HPA039052: AB_10672839" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (3.60e-2)" "unprognostic (3.47e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-1)" "unprognostic (4.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (3.93e-5)" "unprognostic (2.39e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-3)" "unprognostic (2.41e-1)" GLYATL1B GLYATL1P3 ENSG00000255151 "Glycine-N-acyltransferase like 1B" A0A0U1RQE8 11 59086307-59094786 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 7.3;lymphoid tissue: 2.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Lineage enriched" "Detected in single" 15 "B-cells: 1.5" "Cancer enhanced" "Detected in some" "lymphoma: 5.4" "Skin - Sebaceous gland cells" HPA039501 Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (5.20e-2)" "unprognostic (2.62e-1)" "unprognostic (2.11e-1)" "unprognostic (3.21e-4)" "unprognostic (3.45e-1)" GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.9;breast: 17.8;gallbladder: 17.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.7;Enteroendocrine cells: 28.9;Hofbauer cells: 34.6;Kupffer cells: 32.5;Macrophages: 20.0;monocytes: 86.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "classical monocyte: 288.1;intermediate monocyte: 712.0;non-classical monocyte: 695.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.0" "Group enriched" "Detected in some" 5 "lymphoma: 2.6;Neuroblastoma: 2.2;Rhabdoid: 5.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA062890 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 33: Macrophages - Degranulation" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" GPCPD1 "GDE5, GDPD6, KIAA1434" ENSG00000125772 "Glycerophosphocholine phosphodiesterase 1" Q9NPB8 20 5544439-5611006 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.5" "Cell type enhanced" "Detected in many" "Early spermatids: 253.1;Microglial cells: 283.7;monocytes: 161.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042987 Uncertain Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA042987: AB_2678254" "unprognostic (2.25e-2)" "unprognostic (2.45e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.30e-4)" "unprognostic (2.93e-2)" "unprognostic (8.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (3.76e-2)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-2)" GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 8.9;Breast myoepithelial cells: 7.1;Collecting duct cells: 9.8;Cone photoreceptor cells: 8.6;Glandular and luminal cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.2" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA030749, HPA030750" Approved Supported Nucleoplasm NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "CAB002589: AB_10693935, HPA030749: AB_2673590, HPA030750: AB_2673591" "unprognostic (4.83e-3)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.04e-7)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-2)" "unprognostic (1.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" H3-3A "H3.3A, H3F3, H3F3A" ENSG00000163041 "H3.3 histone A" P84243 1 226061851-226072019 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4487.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 4487.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011481, CAB037178, HPA042570" Supported Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: Non-specific - RNA binding" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "CAB011481: AB_880446, CAB037178: AB_532248, HPA042570: AB_2678056" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-3)" "unprognostic (2.83e-2)" "unprognostic (3.74e-1)" "unprognostic (9.83e-3)" "unprognostic (4.71e-2)" "unprognostic (1.77e-3)" "unprognostic (3.69e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (3.66e-2)" "unprognostic (8.03e-3)" "unprognostic (2.21e-3)" "unprognostic (6.03e-2)" HACD4 "Em:AL662879.1, PTPLAD2" ENSG00000188921 "3-hydroxyacyl-CoA dehydratase 4" Q5VWC8 9 20999509-21031640 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 86.4;Kupffer cells: 84.8;Langerhans cells: 71.4;Macrophages: 75.0;monocytes: 90.8;Respiratory ciliated cells: 78.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058666 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA058666: AB_2683793" "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (5.47e-2)" "unprognostic (1.70e-2)" "unprognostic (7.66e-2)" "unprognostic (1.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-4)" "prognostic favorable (3.14e-4)" "unprognostic (8.72e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.89e-3)" "unprognostic (7.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-3)" HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 187.4;Kupffer cells: 178.4;Langerhans cells: 103.8;Macrophages: 142.2;monocytes: 256.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 5 "Leukemia: 21.9;lymphoma: 31.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 78.9;Cholangiocytes: 146.3;dendritic cells: 58.6;Ductal cells: 102.4;Endothelial cells: 71.3;Hepatocytes: 56.4;Hofbauer cells: 72.2;Kupffer cells: 55.1;monocytes: 56.7" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 68.0" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 subunit alpha" Q16665 14 61695513-61748259 "Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 448.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 155.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 155.0" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nuclear bodies" "CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (9.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.77e-2)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (3.58e-1)" "unprognostic (7.35e-2)" "unprognostic (3.88e-2)" HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 12 "Early spermatids: 14.1;Hofbauer cells: 36.9;Kupffer cells: 37.9;Macrophages: 32.7;monocytes: 45.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cancer enhanced" "Detected in single" "Leukemia: 3.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.2;Kupffer cells: 30.1;Macrophages: 24.0;Suprabasal keratinocytes: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Low cancer specificity" "Detected in all" "Breast - Macrophages" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0;heart muscle: 26.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Excitatory neurons: 61.3;Hofbauer cells: 29.2;Kupffer cells: 52.5;Macrophages: 43.8;monocytes: 48.8;Smooth muscle cells: 32.0" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 134.4;neutrophil: 161.7" "Group enriched" "Detected in many" 5 "granulocytes: 161.7;monocytes: 51.6" "Cancer enhanced" "Detected in some" "Leukemia: 9.4;Myeloma: 4.9" "Liver - Neutrophils, Lung - Neutrophil_2, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 208.4;Kupffer cells: 151.9;Langerhans cells: 137.9;Macrophages: 249.0;monocytes: 224.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 943.1;monocytes: 1676.7;NK-cells: 1445.3;Thymic epithelial cells: 998.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23410.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23410.9" "Low cancer specificity" "Detected in all" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 450000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 72: Non-specific - Transcription" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "Cell Junctions" Nucleoplasm "HPA004337: AB_1851427, HPA044731: " "unprognostic (2.39e-2)" "unprognostic (2.69e-2)" "unprognostic (4.54e-1)" "unprognostic (1.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.87e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.37e-9)" "unprognostic (2.79e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "Hofbauer cells: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" NA NA 3750 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 33: Macrophages - Degranulation" "HPA073843: " "unprognostic (2.38e-1)" "unprognostic (2.60e-4)" IFNGR2 "AF-1, IFNGT1" ENSG00000159128 "Interferon gamma receptor 2" P38484 21 33403413-33479348 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 661.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001535 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 33: Skin cancer - Membrane components" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Golgi apparatus" "HPA001535: AB_1078432" "unprognostic (9.58e-2)" "unprognostic (5.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (3.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.53e-2)" "unprognostic (3.25e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (1.13e-10)" "unprognostic (6.74e-3)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (2.15e-3)" IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 69.5" "Cell type enhanced" "Detected in many" "dendritic cells: 203.2;NK-cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Supported "Golgi apparatus,Vesicles" NA NA 190000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 15: Non-specific - Protein binding" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.08e-4)" IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in all" "dendritic cells: 79.1;Kupffer cells: 122.0;Macrophages: 74.5;monocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophil_2, Skin - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 182.8" "Cell type enhanced" "Detected in many" "granulocytes: 42.7;Hofbauer cells: 63.5;Kupffer cells: 175.2;Langerhans cells: 60.9;Macrophages: 90.3;Microglial cells: 40.1;NK-cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Leukemia: 11.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 7 "dendritic cells: 275.0;Hofbauer cells: 105.6;Kupffer cells: 135.5;Langerhans cells: 331.4;Macrophages: 148.9;monocytes: 205.6;T-cells: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Group enriched" "Detected in some" 10 "Leukemia: 6.4;lymphoma: 15.9" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Stomach - T-cells, Testis - Macrophages, Thyroid - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" KCNE1 "IsK, JLNS2, LQT5, minK" ENSG00000180509 "Potassium voltage-gated channel subfamily E regulatory subunit 1" P15382 21 34446688-34512210 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.3;fallopian tube: 10.0;heart muscle: 5.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.9;Kupffer cells: 42.5;Macrophages: 23.2;monocytes: 35.4;Respiratory ciliated cells: 37.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cancer enriched" "Detected in single" 7 "Rhabdoid: 3.3" "Adipose subcutaneous - Macrophages, Prostate - Macrophages" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 33: Macrophages - Degranulation" "unprognostic (8.24e-3)" "unprognostic (9.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.71e-3)" "unprognostic (1.01e-3)" "unprognostic (2.98e-2)" "unprognostic (2.45e-2)" "unprognostic (1.47e-2)" "unprognostic (2.58e-1)" "unprognostic (2.06e-1)" "unprognostic (9.30e-2)" "unprognostic (7.90e-3)" "unprognostic (1.41e-2)" "unprognostic (3.27e-2)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 70.5;stomach 1: 56.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 44.1;Hofbauer cells: 49.3;Kupffer cells: 118.6;Macrophages: 46.0;monocytes: 48.3;Undifferentiated cells: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 48 "basophil: 51.4;classical monocyte: 38.5;eosinophil: 23.4;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.1;non-classical monocyte: 36.6" "Group enriched" "Detected in many" 115 "dendritic cells: 18.3;granulocytes: 53.1;monocytes: 41.8" "Cancer enhanced" "Detected in many" "Bone cancer: 70.6;colorectal cancer: 49.0;Gastric cancer: 52.4" "Adipose subcutaneous - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014849 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 2: DU4475 - Unknown function" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 43.3;monocytes: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: Non-specific - Cilium assembly" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.1;granulocytes: 129.5;Hofbauer cells: 108.1;Kupffer cells: 95.4;Langerhans cells: 105.7;Macrophages: 84.5;monocytes: 53.3;NK-cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 200.2;lymphoma: 105.0" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 296.7;Hofbauer cells: 352.7;Kupffer cells: 434.2;Langerhans cells: 373.3;Late spermatids: 293.1;Macrophages: 482.1;monocytes: 755.7;NK-cells: 534.7;Schwann cells: 352.8;T-cells: 372.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 555.7;lymphoma: 804.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skin - Langerhans cells, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA019493, CAB020673" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Actin filaments, Cytosol" "CAB020673: , HPA000895: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 11.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 19.5;Kupffer cells: 55.3;Macrophages: 31.3;monocytes: 116.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.8;non-classical monocyte: 169.2" "Lineage enriched" "Detected in many" 5 "monocytes: 169.2" "Not detected" "Not detected" "Liver - Kupffer cells, Lung - Neutrophil_2, Prostate - Macrophages, Stomach - Macrophages" NA NA 94000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (4.52e-2)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (9.46e-3)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.90e-2)" "unprognostic (8.72e-2)" "unprognostic (1.13e-1)" "unprognostic (8.28e-3)" "unprognostic (8.82e-2)" "unprognostic (3.79e-4)" "unprognostic (2.53e-1)" "unprognostic (9.83e-2)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 8 "Hofbauer cells: 52.7;Kupffer cells: 69.8;Macrophages: 41.6;monocytes: 102.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 17: RS4;11 - Unknown function" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Cell type enriched" "Detected in some" 4 "monocytes: 458.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 20.2;Kupffer cells: 87.1;Macrophages: 29.8;monocytes: 21.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 27.5;dendritic cells: 59.3;Hofbauer cells: 29.7;Kupffer cells: 49.5;Macrophages: 65.4;Microglial cells: 30.1;monocytes: 169.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 17 "Leukemia: 1.5;lymphoma: 1.8;Myeloma: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Stomach - Macrophages" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "dendritic cells: 117.4;Hofbauer cells: 64.1;Kupffer cells: 246.4;Langerhans cells: 84.7;Macrophages: 119.5;monocytes: 561.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 4 "Hofbauer cells: 88.5;Kupffer cells: 118.4;Macrophages: 81.0;monocytes: 139.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Skin - Macrophages, Thyroid - Neutrophils" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" LINC02218 ENSG00000249662 "Long intergenic non-protein coding RNA 2218" 5 17444010-17486829 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "neutrophil: 8.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 8.6" "Not detected" "Not detected" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 7 "Hofbauer cells: 69.1;Kupffer cells: 95.6;Macrophages: 85.0;monocytes: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;lymphoma: 2.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 869.2;Kupffer cells: 1075.5;Langerhans cells: 1613.4;Macrophages: 784.1;monocytes: 3419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 16 "Leukemia: 40.1" "Adipose visceral - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 10 "B-cells: 154.3;Hofbauer cells: 258.4;Kupffer cells: 157.5;Langerhans cells: 123.9;Macrophages: 146.7;Microglial cells: 103.1;monocytes: 146.5;Schwann cells: 66.4" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Group enriched" "Detected in some" 176 "Leukemia: 38.8;lymphoma: 38.4;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 211.1;dendritic cells: 162.4;Hofbauer cells: 164.2;Macrophages: 197.4;monocytes: 535.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" LYST "CHS, CHS1" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883640 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.3;retina: 27.9" "Cell type enhanced" "Detected in all" "Melanocytes: 179.4;monocytes: 253.5" "Cancer enhanced" "Detected in all" "melanoma: 11.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;monocytes: 6.1" "Cancer enhanced" "Detected in all" "skin cancer: 20.5" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: AB_2682129, HPA055725: AB_2682898" "unprognostic (1.56e-2)" "unprognostic (1.54e-1)" "unprognostic (9.92e-2)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.32e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3373.9;Hofbauer cells: 2648.2;Kupffer cells: 5103.6;Langerhans cells: 5870.5;Macrophages: 4276.5;monocytes: 3002.5;Serous glandular cells: 2631.0" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 1889.9;Leukemia: 787.2" "Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 201.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696305 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411, HPA064376" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "CAB007764: AB_562314, HPA035410: AB_2674614, HPA035411: AB_2674615, HPA064376: " "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 79.0;neutrophil: 24.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 79.0" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 970000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: Non-specific - Protein binding" "Cluster 33: Macrophages - Degranulation" "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" MARF1 "KIAA0430, LKAP, LMKB, PPP1R34" ENSG00000166783 "Meiosis regulator and mRNA stability factor 1" Q9Y4F3 16 15594387-15643154 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017992 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Vesicles" "HPA017992: AB_1852921" "unprognostic (2.33e-1)" "unprognostic (6.44e-3)" "unprognostic (8.84e-2)" "unprognostic (3.78e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" "unprognostic (2.35e-1)" "unprognostic (2.10e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "unprognostic (8.44e-3)" "unprognostic (1.35e-1)" "unprognostic (6.94e-3)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (8.74e-2)" "unprognostic (7.94e-2)" MBD6 KIAA1887 ENSG00000166987 "Methyl-CpG binding domain protein 6" Q96DN6 12 57520710-57530148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038948, HPA038949" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA038948: AB_2676285, HPA038949: AB_10671868" "unprognostic (2.56e-1)" "unprognostic (4.15e-2)" "unprognostic (1.64e-2)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (2.84e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-2)" "unprognostic (3.19e-1)" "unprognostic (1.83e-2)" "unprognostic (6.65e-2)" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (1.73e-1)" "unprognostic (2.24e-1)" "unprognostic (1.01e-2)" MBOAT7 "BB1, hMBOA-7, LENG4, LPLAT" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 108.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "basophil: 157.3;eosinophil: 265.9;neutrophil: 239.1" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA055967: AB_2682990" "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (5.55e-6)" "prognostic unfavorable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favorable (4.31e-4)" MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 5 "Kupffer cells: 17.3;Macrophages: 14.5;monocytes: 46.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cancer enhanced" "Detected in single" "Leukemia: 1.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Breast - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Skin - Macrophages, Thyroid - Neutrophils" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" MEGF9 EGFL5 ENSG00000106780 "Multiple EGF like domains 9" Q9H1U4 9 120600811-120714470 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 68.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 219.6;Alveolar cells type 2: 153.1;Astrocytes: 138.5;Cone photoreceptor cells: 249.9;Oligodendrocytes: 227.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.2" "Group enriched" "Detected in many" 5 "granulocytes: 25.2;monocytes: 7.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014319, HPA050238" Approved Approved Nucleoplasm,Cytosol NA NA 96000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 61: Liver - Metabolism" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA014319: AB_1848035, HPA050238: AB_2681060" "unprognostic (1.18e-1)" "unprognostic (5.33e-2)" "unprognostic (1.84e-1)" "unprognostic (1.75e-2)" "unprognostic (3.30e-1)" "unprognostic (3.68e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-2)" "unprognostic (3.63e-2)" "unprognostic (1.13e-2)" "unprognostic (5.92e-2)" "unprognostic (4.97e-2)" "prognostic favorable (5.48e-11)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "unprognostic (6.78e-2)" "unprognostic (1.41e-1)" METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657473 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 332.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" MFSD14B "FLJ14753, HIATL1" ENSG00000148110 "Major facilitator superfamily domain containing 14B" Q5SR56 9 94374569-94461042 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017978 Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 55: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "HPA017978: AB_2116836" "unprognostic (3.03e-2)" "unprognostic (2.28e-1)" "unprognostic (3.96e-3)" "unprognostic (5.95e-3)" "unprognostic (1.39e-1)" "unprognostic (3.29e-2)" "unprognostic (4.13e-3)" "unprognostic (3.27e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-2)" "unprognostic (1.16e-2)" "unprognostic (3.11e-3)" "unprognostic (1.15e-1)" "unprognostic (9.12e-2)" "unprognostic (6.63e-2)" "unprognostic (1.93e-1)" "unprognostic (9.01e-2)" MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in some" "Kupffer cells: 7.3;Langerhans cells: 3.5;Macrophages: 3.8;Schwann cells: 4.4;Serous glandular cells: 3.9;T-cells: 4.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cancer enhanced" "Detected in some" "Leukemia: 2.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 3.5;Macrophages: 1.3" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cancer enriched" "Detected in some" 40 "skin cancer: 51.6" "Lung - Neutrophil_1, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: Skin cancer - Membrane components" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 427.6;Kupffer cells: 658.3;Langerhans cells: 321.0;Macrophages: 437.6;monocytes: 419.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Cancer enriched" "Detected in some" 12 "Leukemia: 43.6" "Lung - Neutrophil_2, Prostate - Macrophages" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 329.5;Hofbauer cells: 104.2;Kupffer cells: 355.0;Macrophages: 210.1;monocytes: 236.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Group enriched" "Detected in some" 187 "Leukemia: 11.9;lymphoma: 27.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" MSL1 "DKFZp686P24239, hMSL1, MSL-1" ENSG00000188895 "MSL complex subunit 1" Q68DK7 17 40121971-40136917 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022800, HPA023567" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA022800: AB_1853057, HPA023567: AB_1853059" "unprognostic (1.94e-1)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.60e-1)" "unprognostic (1.06e-2)" "unprognostic (2.24e-1)" "unprognostic (3.46e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (3.06e-6)" "unprognostic (2.92e-2)" "unprognostic (7.91e-2)" "unprognostic (5.80e-2)" "unprognostic (2.61e-2)" MSL3 MSL3L1 ENSG00000005302 "MSL complex subunit 3" Q8N5Y2 X 11758159-11775772 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034535, HPA034536" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA034535: AB_10603878, HPA034536: AB_10670973" "unprognostic (2.58e-1)" "unprognostic (1.76e-3)" "unprognostic (1.04e-1)" "unprognostic (9.56e-2)" "unprognostic (5.36e-2)" "prognostic favorable (3.28e-4)" "prognostic unfavorable (4.93e-4)" "unprognostic (8.36e-2)" "unprognostic (2.48e-2)" "unprognostic (4.88e-3)" "unprognostic (2.13e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (3.14e-9)" "unprognostic (1.20e-1)" "unprognostic (2.06e-1)" "unprognostic (4.35e-1)" "prognostic favorable (2.17e-4)" MTF1 ENSG00000188786 "Metal regulatory transcription factor 1" Q14872 1 37809574-37859592 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028604, HPA028689" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 38: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA028604: AB_10600304, HPA028689: AB_10611384" "unprognostic (5.74e-2)" "unprognostic (2.10e-1)" "unprognostic (2.56e-2)" "unprognostic (2.89e-1)" "unprognostic (8.33e-2)" "unprognostic (8.15e-3)" "unprognostic (1.34e-2)" "unprognostic (5.07e-2)" "unprognostic (1.91e-1)" "unprognostic (4.58e-2)" "unprognostic (3.20e-2)" "unprognostic (2.30e-2)" "unprognostic (3.70e-2)" "unprognostic (4.37e-3)" "unprognostic (2.98e-1)" "unprognostic (6.32e-2)" "unprognostic (2.19e-1)" MX2 MXB ENSG00000183486 "MX dynamin like GTPase 2" P20592 21 41361999-41409393 "Plasma proteins, Predicted intracellular proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "dendritic cells: 47.9;Gastric mucus-secreting cells: 42.9;Kupffer cells: 44.8;Langerhans cells: 38.0;Macrophages: 49.1;monocytes: 117.9;Schwann cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 4 "neutrophil: 150.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 150.8" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Lung - NK-cells (Lung)" "Low region specificity" "Detected in all" HPA030235 Uncertain NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 3: T-cells - Adaptive immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 33: Macrophages - Degranulation" "HPA030235: AB_10601970" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "unprognostic (7.90e-3)" "prognostic unfavorable (3.71e-5)" "unprognostic (2.50e-1)" "unprognostic (2.30e-1)" "unprognostic (7.77e-2)" "unprognostic (3.36e-1)" "unprognostic (2.63e-1)" "unprognostic (6.64e-2)" "unprognostic (2.01e-2)" "unprognostic (9.48e-2)" "unprognostic (3.38e-14)" "unprognostic (6.31e-2)" "unprognostic (1.59e-3)" "unprognostic (5.61e-2)" "unprognostic (1.16e-2)" NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 197.5;Prostatic glandular cells: 149.7;Proximal enterocytes: 152.2" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 672.4;non-classical monocyte: 583.3" "Lineage enriched" "Detected in all" 5 "monocytes: 672.4" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 33: Macrophages - Degranulation" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 506.2" "Group enriched" "Detected in all" 7 "granulocytes: 506.2;monocytes: 162.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 38: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA048909: AB_2680553, HPA053368: AB_2682130" "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" NAIP "BIRC1, NLRB1" ENSG00000249437 "NLR family apoptosis inhibitory protein" Q13075 5 70968166-71025339 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 31.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 109.2;Microglial cells: 110.4;Oligodendrocytes: 167.6;Rod photoreceptor cells: 146.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 8.4;myeloid DC: 5.3" "Group enriched" "Detected in many" 16 "dendritic cells: 5.3;granulocytes: 4.4;monocytes: 8.4" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Macrophages, Lung - Neutrophil_2" HPA042438 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA042438: AB_10796578" "unprognostic (9.03e-2)" "unprognostic (6.03e-2)" "unprognostic (1.31e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "unprognostic (1.12e-3)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (4.36e-2)" "unprognostic (1.86e-1)" "unprognostic (2.54e-2)" "unprognostic (5.13e-1)" "unprognostic (1.69e-3)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (1.38e-1)" "unprognostic (9.96e-2)" NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 1408.1;Langerhans cells: 2638.7;Macrophages: 1606.2;monocytes: 3356.4;Serous glandular cells: 1477.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 279.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 279.2" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" NA NA 2140000 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" NBPF10 AG1 ENSG00000271425 "NBPF member 10" 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 18.9;Paneth cells: 29.5;Squamous epithelial cells: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: Non-specific - RNA binding" "Cluster 33: Macrophages - Degranulation" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" NBPF14 DJ328E19.C1.1 ENSG00000270629 "NBPF member 14" 1 148531385-148679742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 92.0;monocytes: 51.1;Paneth cells: 115.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: Non-specific - RNA binding" "Cluster 33: Macrophages - Degranulation" Cytosol Microtubules "HPA038748: AB_2676188, HPA038752: , HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.28e-2)" "unprognostic (3.88e-2)" "unprognostic (7.92e-3)" "unprognostic (7.13e-2)" "unprognostic (2.46e-1)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (7.69e-4)" "unprognostic (7.23e-3)" "unprognostic (5.20e-2)" "unprognostic (5.15e-4)" "unprognostic (2.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-1)" "unprognostic (2.52e-2)" NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 72.8;granulocytes: 74.1;Hofbauer cells: 204.4;Kupffer cells: 58.9;Langerhans cells: 56.1;Macrophages: 98.8;Plasma cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Group enriched" "Detected in some" 7 "Leukemia: 116.3;lymphoma: 49.4" "Breast - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.3;granulocytes: 19.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA051515: AB_2681517" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 26.0;Kupffer cells: 68.0;Macrophages: 32.4;monocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cancer enriched" "Detected in single" 8 "Leukemia: 5.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 29.1;Endothelial cells: 32.5;Kupffer cells: 33.0;Microglial cells: 19.2;monocytes: 27.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cancer enhanced" "Detected in some" "Neuroblastoma: 10.4;testis cancer: 7.1" "Liver - Vascular Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" NLRP12 "CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2" ENSG00000142405 "NLR family pyrin domain containing 12" P59046 19 53793741-53824394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.3" "Group enriched" "Detected in some" 5 "Hofbauer cells: 6.7;Kupffer cells: 14.4;Macrophages: 7.8;monocytes: 9.9" "Cancer enriched" "Detected in single" 5 "testis cancer: 2.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;classical monocyte: 18.1;eosinophil: 23.2;neutrophil: 29.8" "Group enriched" "Detected in many" 5 "granulocytes: 56.9;monocytes: 18.1" "Cancer enhanced" "Detected in single" "Leukemia: 1.8" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042981 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA042981: AB_10795712" "unprognostic (6.92e-2)" "unprognostic (3.11e-1)" "unprognostic (6.66e-3)" "unprognostic (9.82e-2)" "unprognostic (1.81e-4)" "unprognostic (3.90e-2)" "unprognostic (5.79e-2)" "unprognostic (6.26e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-5)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-2)" "unprognostic (4.48e-1)" NMI ENSG00000123609 "N-myc and STAT interactor" Q13287 2 151270470-151289894 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008588 Approved Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "HPA008588: AB_1079493" "unprognostic (5.28e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.42e-2)" "unprognostic (1.08e-1)" "unprognostic (4.51e-3)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.91e-1)" "unprognostic (4.69e-2)" "unprognostic (1.52e-2)" "unprognostic (4.57e-2)" NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" NPIPA8 LCR16a9 ENSG00000214940 "Nuclear pore complex interacting protein family member A8" P0DM63 16 18317942-18336736 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebral cortex: 28.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 38.5" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (1.68e-1)" "unprognostic (3.60e-2)" "unprognostic (2.81e-1)" NUMB C14orf41 ENSG00000133961 "NUMB endocytic adaptor protein" P49757 14 73275107-73458617 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 290.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002874, CAB011478" Approved Enhanced "Cell Junctions" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 46: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" "Cell Junctions" "CAB011478: AB_443023, HPA002874: " "unprognostic (5.28e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-3)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.33e-2)" "unprognostic (4.08e-3)" "unprognostic (2.65e-3)" "unprognostic (4.14e-2)" "prognostic favorable (2.32e-6)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (3.92e-2)" "unprognostic (2.87e-1)" NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125586-131234663 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 124.2" "Cell type enhanced" "Detected in many" "Early spermatids: 245.3;Granulosa cells: 157.4;Hofbauer cells: 175.4;Kupffer cells: 256.7;Late spermatids: 401.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 425.3;neutrophil: 1259.6" "Group enriched" "Detected in all" 5 "granulocytes: 1259.6;monocytes: 425.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" OR1A1 OR17-7 ENSG00000172146 "Olfactory receptor family 1 subfamily A member 1" Q9P1Q5 17 3207539-3218896 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "brain: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 52: Spermatids - Smell perception" "Cluster 33: Macrophages - Degranulation" OR2AP1 OR2AP1P ENSG00000179615 "Olfactory receptor family 2 subfamily AP member 1" Q8NGE2 12 55572468-55575612 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 33: Macrophages - Degranulation" OR52K1 ENSG00000196778 "Olfactory receptor family 52 subfamily K member 1" Q8NGK4 11 4482646-4493497 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "bone marrow: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 52: Spermatids - Smell perception" "Cluster 33: Macrophages - Degranulation" OR52K2 ENSG00000181963 "Olfactory receptor family 52 subfamily K member 2" Q8NGK3 11 4449295-4450361 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.3" "Lineage enhanced" "Detected in single" "granulocytes: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 33: Macrophages - Degranulation" OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 118.2" "Group enriched" "Detected in some" 4 "granulocytes: 42.3;Hofbauer cells: 162.0;Macrophages: 48.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.2;neutrophil: 34.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.2" "Group enriched" "Detected in some" 4 "breast cancer: 3.2;Leukemia: 10.2;lymphoma: 7.8" "Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 39700 "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 24.2;Kupffer cells: 38.1;Macrophages: 63.2;Microglial cells: 64.8;monocytes: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Kidney - Macrophages, Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "bone marrow: 105.1;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in some" "dendritic cells: 14.8;granulocytes: 5.6;Hofbauer cells: 8.0;Kupffer cells: 5.3;Macrophages: 8.8;monocytes: 16.0;NK-cells: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0" "Group enriched" "Detected in all" 9 "granulocytes: 183.0;monocytes: 71.3" "Cancer enriched" "Detected in single" 11 "Leukemia: 3.3" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Sebaceous gland cells, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 29000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Melanocytes: 203.8;Microglial cells: 162.4;monocytes: 420.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 15.3;lymphoma: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.3;Kupffer cells: 5.4;Macrophages: 2.0;monocytes: 2.2;NK-cells: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Not detected" "Not detected" "Colon - Macrophages, Pancreas - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase O95336 19 17511636-17521288 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040744, HPA042032" Approved Supported Nucleoplasm,Cytosol NA NA 7200000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA040744: AB_2677111, HPA042032: AB_2677809" "unprognostic (3.68e-2)" "unprognostic (8.98e-3)" "unprognostic (1.25e-1)" "unprognostic (9.64e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (2.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.75e-3)" "unprognostic (2.39e-1)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (9.26e-3)" PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.7;Inhibitory neurons: 1.4;Serous glandular cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378649-78425114 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" "HPA022526: AB_1855271" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (5.76e-3)" "unprognostic (3.17e-2)" "unprognostic (8.46e-3)" "prognostic favorable (7.33e-5)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (1.16e-5)" "unprognostic (9.94e-2)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" PHF20L1 "CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B" ENSG00000129292 "PHD finger protein 20 like 1" A8MW92 8 132775358-132848807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025060, HPA028417" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Plasma membrane" "HPA025060: AB_10599822, HPA028417: AB_10602278" "unprognostic (9.12e-3)" "unprognostic (2.29e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-3)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (2.79e-2)" "unprognostic (7.53e-2)" "unprognostic (9.66e-2)" "unprognostic (1.24e-2)" "unprognostic (8.85e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.83e-2)" PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 64.6;Hofbauer cells: 63.6;Kupffer cells: 118.5;Macrophages: 97.0;Microglial cells: 59.3;monocytes: 126.1;Serous glandular cells: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cancer enhanced" "Detected in many" "Leukemia: 53.0;lymphoma: 85.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.7;Kupffer cells: 40.2;Macrophages: 42.0;Microglial cells: 38.3;monocytes: 57.5;NK-cells: 23.1;Schwann cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.3" "Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 55.8;Kupffer cells: 68.1;Macrophages: 64.5;Melanocytes: 168.9;monocytes: 92.0" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cancer enhanced" "Detected in many" "Myeloma: 32.5" "Skin - Melanocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 33: Macrophages - Degranulation" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" PPP1R3D PPP1R6 ENSG00000132825 "Protein phosphatase 1 regulatory subunit 3D" O95685 20 59936663-59940305 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041146 Approved Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" "Vesicles, Mitochondria" Nucleoli "HPA041146: AB_10793870" "unprognostic (2.50e-3)" "unprognostic (3.55e-3)" "unprognostic (6.90e-2)" "unprognostic (1.23e-1)" "unprognostic (7.23e-2)" "unprognostic (5.87e-2)" "unprognostic (5.73e-2)" "unprognostic (2.39e-3)" "unprognostic (5.54e-2)" "unprognostic (3.27e-1)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.48e-2)" "prognostic favorable (9.14e-4)" "unprognostic (4.71e-2)" "unprognostic (1.47e-2)" "unprognostic (5.71e-2)" PRAM1 PML-RAR ENSG00000133246 "PML-RARA regulated adaptor molecule 1" Q96QH2 19 8490056-8502640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 97.0" "Group enriched" "Detected in some" 5 "Hofbauer cells: 50.8;Kupffer cells: 72.4;Macrophages: 47.7;monocytes: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 95.4;intermediate monocyte: 101.3;myeloid DC: 58.6;neutrophil: 54.0;non-classical monocyte: 121.4" "Group enriched" "Detected in many" 7 "dendritic cells: 58.6;granulocytes: 54.0;monocytes: 121.4" "Cancer enriched" "Detected in single" 68 "Leukemia: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045236, HPA050161" Approved Approved "Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "HPA045236: AB_2679267, HPA050161: AB_2681036" "unprognostic (1.68e-2)" "unprognostic (3.79e-3)" "unprognostic (1.15e-2)" "unprognostic (3.91e-3)" "unprognostic (1.25e-1)" "unprognostic (6.54e-3)" "unprognostic (3.36e-1)" "unprognostic (1.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.73e-1)" "unprognostic (2.15e-3)" "unprognostic (2.72e-1)" "unprognostic (6.12e-3)" PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.3;Hofbauer cells: 5.0;Kupffer cells: 10.0;Macrophages: 11.1;Serous glandular cells: 9.4;Spermatocytes: 18.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cancer enhanced" "Detected in some" "Leukemia: 8.0;Myeloma: 5.9" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Testis - Early spermatids, Thyroid - Neutrophils" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase 4A2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 789.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain NA NA 490000 "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "CAB011204: AB_532271, HPA003281: AB_1855903" "unprognostic (2.67e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-3)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (6.20e-2)" "prognostic unfavorable (2.62e-5)" "unprognostic (6.90e-2)" "unprognostic (4.63e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.10e-11)" "unprognostic (1.16e-2)" "unprognostic (3.81e-1)" "unprognostic (2.89e-1)" "prognostic favorable (2.72e-5)" RAB3D "D2-2, GOV, RAB16, RAD3D" ENSG00000105514 "RAB3D, member RAS oncogene family" O95716 19 11322068-11346270 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.5;skin 1: 53.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.7;Squamous epithelial cells: 52.3;Suprabasal keratinocytes: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 73.1" "CAB018067, HPA063283" Approved Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 65: Breast cancer - Unknown function" "Cluster 33: Macrophages - Degranulation" Vesicles "CAB018067: AB_606903, HPA063283: AB_2684976" "unprognostic (4.71e-3)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (4.17e-3)" "unprognostic (7.27e-3)" "unprognostic (1.55e-1)" "unprognostic (2.80e-1)" "unprognostic (8.76e-2)" "unprognostic (9.92e-2)" "unprognostic (4.45e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (9.15e-2)" "unprognostic (1.34e-1)" RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "granulocytes: 28.0;Hofbauer cells: 22.7;Kupffer cells: 34.2;Langerhans cells: 15.0;Macrophages: 20.9;monocytes: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Leukemia: 7.3" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 217.0;retina: 162.8" "Cell type enhanced" "Detected in many" "dendritic cells: 121.9;Kupffer cells: 110.3;Langerhans cells: 85.6;Macrophages: 78.8;monocytes: 160.9;Oligodendrocytes: 100.7;Peritubular cells: 149.7;Rod photoreceptor cells: 139.5" "Cancer enriched" "Detected in all" 5 "glioma: 48.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.0;lymphoma: 40.0" "Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: AB_2681386" "unprognostic (6.51e-2)" "unprognostic (3.67e-3)" "unprognostic (5.31e-2)" "unprognostic (1.47e-2)" "unprognostic (3.15e-1)" "unprognostic (1.46e-3)" "unprognostic (2.80e-1)" "unprognostic (7.01e-2)" "unprognostic (1.38e-2)" "unprognostic (2.41e-2)" "unprognostic (4.93e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (6.46e-2)" RGS19 "GAIP, RGSGAIP" ENSG00000171700 "Regulator of G protein signaling 19" P49795 20 64073181-64079988 "Predicted intracellular proteins" Autophagy "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.2;lymphoid tissue: 77.5" "Cell type enhanced" "Detected in many" "B-cells: 97.8;Hofbauer cells: 164.1;Kupffer cells: 82.3;Macrophages: 99.3;monocytes: 175.4;NK-cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056384, HPA069984" Enhanced Supported "Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Cell Junctions" "Nucleoli fibrillar center" "HPA056384: AB_2732602, HPA069984: AB_2732145" "unprognostic (3.98e-2)" "unprognostic (2.32e-1)" "unprognostic (4.26e-3)" "unprognostic (8.42e-2)" "unprognostic (2.03e-1)" "unprognostic (9.94e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.25e-2)" "unprognostic (2.41e-2)" "unprognostic (3.91e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "prognostic unfavorable (2.06e-9)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (4.66e-3)" RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 61.0;Ionocytes: 56.5;Kupffer cells: 77.7;Langerhans cells: 56.1;Macrophages: 53.9;monocytes: 55.0;NK-cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 5: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" RHOG "ARHG, MGC125835, MGC125836" ENSG00000177105 "Ras homolog family member G" P84095 11 3826978-3840959 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 273.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 304.4;Kupffer cells: 236.8;Langerhans cells: 416.8;Macrophages: 237.6;monocytes: 436.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophil_2" "Low region specificity" "Detected in all" HPA039871 Enhanced NA NA 86000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA039871: AB_10673428" "unprognostic (2.39e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (2.26e-2)" "unprognostic (1.35e-1)" "unprognostic (4.21e-2)" "unprognostic (4.27e-3)" "unprognostic (7.28e-2)" "unprognostic (1.71e-2)" "unprognostic (3.28e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (9.49e-8)" "unprognostic (9.38e-2)" "unprognostic (8.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" RIN3 FLJ22439 ENSG00000100599 "Ras and Rab interactor 3" Q8TB24 14 92513781-92688994 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.3" "Cell type enhanced" "Detected in many" "granulocytes: 62.8;Kupffer cells: 99.7;Langerhans cells: 64.4;Macrophages: 82.0;Microglial cells: 97.6;monocytes: 178.9;NK-cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 35.7;classical monocyte: 43.4;eosinophil: 54.1;intermediate monocyte: 40.4;myeloid DC: 41.6;neutrophil: 40.2;NK-cell: 21.5;non-classical monocyte: 50.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA079218 Approved NA NA 7400 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA079218: " "unprognostic (1.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (1.87e-1)" "unprognostic (7.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.44e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (3.07e-3)" "unprognostic (5.69e-3)" "unprognostic (5.13e-2)" "unprognostic (5.90e-3)" "unprognostic (2.88e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" RIPOR2 "C6orf32, DIFF48, FAM65B, KIAA0386, MYONAP" ENSG00000111913 "RHO family interacting cell polarization regulator 2" Q9Y4F9 6 24804282-25042170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Differentiation, Hearing, Myogenesis" "Developmental protein, Signal transduction inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.6" "Cell type enhanced" "Detected in many" "B-cells: 259.2;dendritic cells: 148.2;Kupffer cells: 249.2;monocytes: 273.0;NK-cells: 202.2;Syncytiotrophoblasts: 141.6;T-cells: 143.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 951.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 951.9" "Cancer enhanced" "Detected in many" "lymphoma: 46.0" "Adipose visceral - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (4.05e-3)" "unprognostic (1.34e-3)" "unprognostic (3.55e-2)" "unprognostic (1.91e-2)" "unprognostic (1.47e-2)" "unprognostic (1.75e-2)" "unprognostic (5.89e-4)" "unprognostic (2.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.40e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-2)" "unprognostic (8.55e-2)" "unprognostic (3.33e-2)" "unprognostic (2.30e-2)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enriched" "Detected in some" 5 "Kupffer cells: 377.3" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Cancer enriched" "Detected in single" 217 "Leukemia: 164.5" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 133.7;dendritic cells: 427.9;Hofbauer cells: 263.8;Kupffer cells: 391.5;Langerhans cells: 225.3;Macrophages: 270.2;Schwann cells: 226.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 22.4;lymphoma: 7.3;Myeloma: 9.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 365.3;monocytes: 505.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 619.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 619.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" RNF24 G1L ENSG00000101236 "Ring finger protein 24" Q9Y225 20 3927309-4015558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.9;Inhibitory neurons: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 238.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 238.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011900 Approved Supported "Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "HPA011900: AB_10671089" "unprognostic (6.61e-2)" "unprognostic (6.56e-2)" "unprognostic (1.72e-1)" "unprognostic (1.17e-2)" "unprognostic (8.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.65e-1)" "unprognostic (5.87e-2)" "unprognostic (2.66e-2)" "unprognostic (5.19e-3)" "unprognostic (3.42e-1)" "prognostic unfavorable (2.67e-7)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 197.1;Kupffer cells: 135.4;monocytes: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3489.7" "Group enriched" "Detected in many" 11 "Hofbauer cells: 394.8;Kupffer cells: 1324.3;Macrophages: 458.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 1321.1;neutrophil: 1781.4" "Group enriched" "Detected in many" 13 "granulocytes: 1781.4;monocytes: 1321.1" "Cancer enhanced" "Detected in some" "cervical cancer: 9.4;head and neck cancer: 7.2" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "HPA002881, CAB025872" Enhanced "Secreted to blood" NA NA 28500000 8300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 33: Macrophages - Degranulation" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" S100Z "Gm625, S100-zeta" ENSG00000171643 "S100 calcium binding protein Z" Q8WXG8 5 76850001-76921650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;lymphoid tissue: 3.2" "Group enriched" "Detected in some" 5 "Hofbauer cells: 13.6;Kupffer cells: 18.5;Macrophages: 12.3;Microglial cells: 31.9;monocytes: 33.8" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 35.0;eosinophil: 31.8;intermediate monocyte: 34.0;myeloid DC: 19.5;neutrophil: 11.8;non-classical monocyte: 39.6" "Group enriched" "Detected in many" 6 "dendritic cells: 19.5;granulocytes: 31.8;monocytes: 39.6" "Group enriched" "Detected in some" 5 "Leukemia: 5.4;lymphoma: 17.5" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" HPA051929 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "Centrosome, Cytosol" Nucleoplasm "HPA051929: AB_2732571" "unprognostic (4.17e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-4)" "unprognostic (1.86e-1)" "unprognostic (4.62e-2)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (8.89e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-3)" "unprognostic (1.32e-1)" "unprognostic (9.47e-5)" "unprognostic (3.39e-4)" "unprognostic (8.94e-2)" "unprognostic (6.85e-2)" "unprognostic (1.62e-1)" SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 309.8;Kupffer cells: 238.9;Macrophages: 310.4;monocytes: 380.6;Schwann cells: 675.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported Nucleoplasm NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Group enriched" "Detected in many" 7 "B-cells: 78.9;Hofbauer cells: 42.8;Kupffer cells: 89.4;Macrophages: 63.9;monocytes: 119.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cancer enhanced" "Detected in many" "lymphoma: 15.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 90.4" "Cell type enhanced" "Detected in many" "Kupffer cells: 107.0;Macrophages: 36.4;monocytes: 89.9;Mucus glandular cells: 49.0;Proximal enterocytes: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 154.2" "Group enriched" "Detected in many" 13 "granulocytes: 154.2;monocytes: 58.2" "Cancer enhanced" "Detected in many" "cervical cancer: 86.2" "Stomach - Macrophages" "Low region specificity" "Detected in some" HPA051214 Approved "Secreted to blood" NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 33: Macrophages - Degranulation" "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" SERPINB10 "bomapin, PI10" ENSG00000242550 "Serpin family B member 10" P48595 18 63897174-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "bone marrow: 74.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 1.7;Club cells: 1.6;Ionocytes: 2.2;Kupffer cells: 2.9;Macrophages: 1.3;Respiratory ciliated cells: 1.4;Theca cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;eosinophil: 1.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 12.8" "Lung - Neutrophil_1, Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA015480, HPA059582" Uncertain Supported Nucleoplasm,Cytosol NA NA 59000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA015480: AB_1855456, HPA059582: AB_2684072" "unprognostic (4.66e-1)" "unprognostic (5.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.56e-1)" "unprognostic (4.59e-1)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (1.25e-4)" SH3BP2 "CRBM, RES4-23" ENSG00000087266 "SH3 domain binding protein 2" P78314 4 2793071-2841098 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036789, HPA036790" Approved Approved "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "HPA036789: , HPA036790: AB_10671712" "unprognostic (7.86e-2)" "unprognostic (3.45e-1)" "unprognostic (9.83e-2)" "prognostic unfavorable (5.42e-6)" "prognostic unfavorable (9.52e-4)" "prognostic favorable (1.57e-5)" "unprognostic (6.58e-2)" "unprognostic (3.16e-2)" "unprognostic (3.17e-2)" "unprognostic (6.41e-3)" "unprognostic (3.35e-2)" "unprognostic (3.30e-2)" "unprognostic (3.24e-3)" "unprognostic (1.78e-2)" "unprognostic (5.32e-1)" "unprognostic (1.78e-1)" "prognostic favorable (2.67e-4)" SHKBP1 "PP203, Sb1" ENSG00000160410 "SH3KBP1 binding protein 1" Q8TBC3 19 40576853-40591399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 98.3;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041887 Uncertain Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 33: Macrophages - Degranulation" "Cell Junctions" "HPA041887: AB_10794639" "unprognostic (1.26e-1)" "unprognostic (7.55e-2)" "unprognostic (1.38e-1)" "unprognostic (4.52e-2)" "unprognostic (8.24e-2)" "unprognostic (9.14e-2)" "unprognostic (1.66e-3)" "unprognostic (3.53e-2)" "unprognostic (6.98e-2)" "unprognostic (6.69e-3)" "unprognostic (1.42e-1)" "unprognostic (6.87e-2)" "unprognostic (5.29e-2)" "unprognostic (6.15e-2)" "unprognostic (2.67e-1)" "unprognostic (1.65e-1)" "unprognostic (8.64e-2)" SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 32.3;Kupffer cells: 75.6;Macrophages: 62.9;monocytes: 132.9;Schwann cells: 25.4" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Group enriched" "Detected in many" 7 "Leukemia: 9.9;lymphoma: 31.8" "Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" SIGLEC12 "S2V, Siglec-12, Siglec-L1, Siglec-XII, SIGLECL1, SLG" ENSG00000254521 "Sialic acid binding Ig like lectin 12" Q96PQ1 19 51491227-51501800 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.1;lymphoid tissue: 14.9" "Group enriched" "Detected in some" 5 "granulocytes: 1.8;Hofbauer cells: 3.4;Kupffer cells: 2.9;Macrophages: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "Leukemia: 17.7" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-2)" "unprognostic (9.13e-2)" "unprognostic (9.58e-4)" "unprognostic (1.38e-1)" "unprognostic (3.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (3.73e-1)" "unprognostic (1.29e-2)" "unprognostic (6.79e-2)" "unprognostic (9.21e-5)" "unprognostic (2.45e-1)" "unprognostic (1.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-1)" SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Group enriched" "Detected in some" 4 "Hofbauer cells: 23.6;Kupffer cells: 47.9;Macrophages: 20.3;monocytes: 27.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Cancer enriched" "Detected in single" 7 "Leukemia: 4.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000105501 "Sialic acid binding Ig like lectin 5" O15389 19 51611927-51645545 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.7;lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.4;Kupffer cells: 10.7;Macrophages: 3.6;monocytes: 3.3" "Cancer enriched" "Detected in single" 5 "urothelial cancer: 1.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "neutrophil: 152.5;non-classical monocyte: 49.3" "Group enriched" "Detected in many" 6 "granulocytes: 152.5;monocytes: 49.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 3.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2" "HPA009085, CAB024900" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB024900: , HPA009085: AB_1079965" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (3.28e-1)" "unprognostic (7.44e-2)" "unprognostic (1.01e-1)" "unprognostic (4.05e-1)" "unprognostic (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (3.55e-3)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Group enriched" "Detected in some" 10 "dendritic cells: 36.0;Hofbauer cells: 29.7;Kupffer cells: 70.2;Macrophages: 32.0;monocytes: 48.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Cancer enhanced" "Detected in many" "Leukemia: 18.2;Sarcoma: 15.1;thyroid cancer: 22.7" "Adipose subcutaneous - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 8.0;Kupffer cells: 17.3;Langerhans cells: 4.0;Macrophages: 11.8;Microglial cells: 13.7;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" SKAP2 "RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R" ENSG00000005020 "Src kinase associated phosphoprotein 2" O75563 7 26667068-26995239 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 282.0;Late spermatids: 386.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005560, HPA024045" Enhanced Supported Nucleoplasm,Cytosol NA NA 1000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 63: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Cytosol "HPA005560: AB_2667360, HPA024045: AB_2671416" "unprognostic (8.52e-2)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (5.62e-2)" "unprognostic (7.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (4.15e-3)" "unprognostic (1.82e-1)" "unprognostic (1.41e-2)" "unprognostic (1.26e-2)" "unprognostic (3.80e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (3.51e-2)" SLC12A6 "ACCPN, KCC3" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" Neuropathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.4" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA034563: AB_10603887" "unprognostic (3.53e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (3.60e-1)" "unprognostic (3.55e-2)" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (2.88e-1)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.58e-2)" "unprognostic (1.83e-1)" "prognostic favorable (3.33e-6)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.41e-1)" SLC25A40 MCFP ENSG00000075303 "Solute carrier family 25 member 40" Q8TBP6 7 87833568-87876360 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055197 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 33: Macrophages - Degranulation" "HPA055197: AB_2682735" "unprognostic (4.19e-2)" "unprognostic (1.01e-1)" "unprognostic (7.30e-2)" "unprognostic (2.15e-1)" "unprognostic (8.80e-2)" "unprognostic (4.03e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.73e-1)" "unprognostic (3.51e-2)" "unprognostic (3.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.78e-2)" "prognostic favorable (1.52e-5)" "unprognostic (8.42e-2)" "unprognostic (2.45e-1)" "unprognostic (2.88e-2)" "unprognostic (4.85e-2)" SLC2A6 "GLUT6, GLUT9, HSA011372" ENSG00000160326 "Solute carrier family 2 member 6" Q9UGQ3 9 133471094-133479127 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "dendritic cells: 45.0;Horizontal cells: 41.0;monocytes: 147.4;Rod photoreceptor cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042272, CAB046014" Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "CAB046014: AB_2270444, HPA042272: AB_2677924" "unprognostic (2.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (1.71e-3)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.93e-2)" "unprognostic (1.05e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (1.02e-11)" "unprognostic (7.24e-2)" "unprognostic (3.43e-2)" "unprognostic (9.36e-2)" "unprognostic (6.28e-3)" SLC35E3 BLOV1 ENSG00000175782 "Solute carrier family 35 member E3" Q7Z769 12 68746125-68793964 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "monocytes: 117.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049403 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "HPA049403: AB_2680747" "unprognostic (1.49e-1)" "unprognostic (6.47e-2)" "unprognostic (2.19e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.61e-2)" "unprognostic (2.49e-1)" "unprognostic (1.26e-4)" "unprognostic (2.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-2)" "unprognostic (6.98e-2)" "unprognostic (6.85e-3)" "unprognostic (1.48e-1)" "unprognostic (3.22e-2)" "unprognostic (2.89e-3)" "unprognostic (1.80e-1)" SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: AB_2190238" "unprognostic (1.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (1.08e-3)" "unprognostic (7.83e-3)" "unprognostic (3.06e-2)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (8.04e-3)" "unprognostic (7.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.74e-1)" "unprognostic (9.45e-3)" "unprognostic (4.20e-2)" SMCR8 "DENND8A, FLJ34716" ENSG00000176994 "SMCR8-C9orf72 complex subunit" Q8TEV9 17 18315293-18328056 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021557, HPA024646" Uncertain Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 49: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA021557: AB_1857283, HPA024646: AB_1857284" "unprognostic (1.69e-1)" "unprognostic (2.25e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (4.34e-3)" "unprognostic (2.11e-3)" "unprognostic (3.02e-2)" "unprognostic (3.18e-1)" "unprognostic (1.48e-2)" "unprognostic (5.09e-3)" "unprognostic (7.11e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.41e-3)" "unprognostic (4.35e-2)" "unprognostic (1.55e-2)" "unprognostic (9.27e-2)" SNX11 ENSG00000002919 "Sorting nexin 11" Q9Y5W9 17 48103357-48123601 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044787, HPA054660" Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" Vesicles "HPA044787: AB_10795988, HPA054660: AB_2682560" "unprognostic (1.75e-1)" "unprognostic (6.86e-3)" "unprognostic (4.34e-2)" "unprognostic (4.33e-3)" "unprognostic (2.45e-1)" "unprognostic (1.54e-1)" "unprognostic (2.68e-3)" "unprognostic (2.07e-1)" "unprognostic (9.27e-2)" "unprognostic (2.15e-1)" "unprognostic (5.42e-2)" "unprognostic (2.12e-1)" "unprognostic (5.22e-3)" "unprognostic (9.02e-3)" "unprognostic (2.70e-2)" "unprognostic (9.50e-2)" "unprognostic (3.89e-2)" SNX18 "SH3PX2, SH3PXD3B, SNAG1" ENSG00000178996 "Sorting nexin 18" Q96RF0 5 54517759-54546586 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0" "Cell type enhanced" "Detected in many" "monocytes: 201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037800 Approved Approved Cytosol NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA037800: AB_10672465" "unprognostic (2.22e-2)" "unprognostic (3.96e-3)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (4.12e-1)" "unprognostic (2.22e-1)" "unprognostic (9.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (9.13e-2)" "unprognostic (3.81e-3)" "prognostic favorable (1.58e-4)" "unprognostic (6.79e-3)" "unprognostic (7.96e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 243.8;Microglial cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" SP1 ENSG00000185591 "Sp1 transcription factor" P08047 12 53380176-53416446 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000330, HPA001853, HPA012292" Supported Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 52: Non-specific - Ribosome" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "CAB000330: AB_2171049, HPA001853: AB_1080069, HPA012292: AB_1857394" "unprognostic (1.12e-1)" "unprognostic (8.52e-3)" "unprognostic (6.11e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (4.64e-3)" "unprognostic (1.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.38e-2)" "unprognostic (5.14e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (4.77e-2)" "unprognostic (2.12e-2)" SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" SPIC "MGC40611, SPI-C" ENSG00000166211 "Spi-C transcription factor" Q8N5J4 12 101475336-101486997 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 30.8" "Cell type enriched" "Detected in single" 11 "Macrophages: 11.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 8 "monocytes: 1.1" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.0" "Liver - Kupffer cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (9.82e-2)" "unprognostic (2.43e-2)" "unprognostic (9.03e-3)" "unprognostic (2.51e-1)" "unprognostic (4.85e-2)" "unprognostic (5.78e-2)" "unprognostic (5.30e-2)" "unprognostic (1.77e-1)" STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" Cytosol Nucleoplasm "HPA001861: AB_1080106" "unprognostic (3.43e-3)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" "unprognostic (6.70e-2)" "unprognostic (1.88e-2)" "unprognostic (3.65e-1)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "prognostic favorable (7.76e-4)" "prognostic favorable (1.14e-4)" STX10 "hsyn10, SYN10" ENSG00000104915 "Syntaxin 10" O60499 19 13144058-13150383 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035303, HPA056439" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus, Vesicles" "HPA035303: AB_10671932, HPA056439: AB_2683135" "unprognostic (1.72e-2)" "unprognostic (2.26e-2)" "unprognostic (1.62e-2)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-3)" "prognostic favorable (8.26e-4)" "unprognostic (4.09e-1)" "unprognostic (3.66e-2)" "unprognostic (4.57e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (2.39e-3)" "unprognostic (7.95e-2)" "unprognostic (2.23e-1)" "unprognostic (2.98e-2)" STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 370.5;Kupffer cells: 357.0;monocytes: 627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 53: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.0;dendritic cells: 122.3;Hofbauer cells: 80.8;Kupffer cells: 89.6;Macrophages: 105.2;Microglial cells: 111.3;monocytes: 85.4;Plasma cells: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 76.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" TICAM2 "TICAM-2, TIRP, TRAM" ENSG00000243414 "Toll like receptor adaptor molecule 2" Q86XR7 5 115578496-115602479 "Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.8;Langerhans cells: 2.2;Macrophages: 2.9;monocytes: 3.3;Plasma cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.78e-1)" "unprognostic (4.27e-4)" "unprognostic (6.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.37e-2)" "unprognostic (2.08e-3)" "unprognostic (1.58e-1)" "unprognostic (6.56e-3)" "unprognostic (1.63e-1)" "unprognostic (1.44e-2)" "unprognostic (1.62e-1)" "unprognostic (3.27e-1)" "unprognostic (2.94e-4)" "unprognostic (9.82e-2)" "unprognostic (1.31e-2)" "unprognostic (1.00e-3)" "unprognostic (1.83e-1)" TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.1" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA054116: AB_2682386" "unprognostic (5.57e-2)" "prognostic favorable (2.09e-5)" "unprognostic (5.18e-2)" "unprognostic (5.13e-2)" "unprognostic (1.15e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (5.53e-2)" "unprognostic (6.74e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (4.90e-2)" "unprognostic (2.43e-1)" "unprognostic (6.71e-2)" "unprognostic (6.29e-2)" "unprognostic (2.74e-1)" TLR1 "CD281, KIAA0012, rsc786" ENSG00000174125 "Toll like receptor 1" Q15399 4 38790677-38856817 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3;lymphoid tissue: 26.9" "Cell type enhanced" "Detected in many" "B-cells: 17.5;Hofbauer cells: 19.4;Kupffer cells: 24.8;Langerhans cells: 19.6;Macrophages: 35.5;Microglial cells: 28.3;monocytes: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 128.5" "Group enriched" "Detected in all" 6 "granulocytes: 128.5;monocytes: 42.7" "Cancer enhanced" "Detected in many" "lymphoma: 8.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Neutrophil_2, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (7.82e-2)" "unprognostic (3.35e-3)" "unprognostic (4.02e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-2)" "unprognostic (1.76e-1)" "unprognostic (7.25e-3)" "unprognostic (4.08e-2)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (3.97e-2)" TLR5 "FLJ10052, MGC126430, MGC126431, SLEB1, TIL3" ENSG00000187554 "Toll like receptor 5" O60602 1 223109404-223143248 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.2" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 30.8;intermediate monocyte: 28.1;myeloid DC: 23.4;neutrophil: 25.3;non-classical monocyte: 12.4" "Group enriched" "Detected in many" 11 "dendritic cells: 23.4;granulocytes: 25.3;monocytes: 30.8" "Low cancer specificity" "Detected in some" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009013 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB009013: AB_2240732" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-2)" "unprognostic (3.81e-2)" "unprognostic (3.09e-2)" "unprognostic (6.83e-2)" "unprognostic (1.49e-2)" "unprognostic (2.71e-1)" "unprognostic (4.23e-3)" "unprognostic (1.46e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.06e-3)" "unprognostic (5.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38823715-38856817 "CD markers, Enzymes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 14.4;Hofbauer cells: 8.6;Macrophages: 15.3;Microglial cells: 20.1;monocytes: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 13.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 33: Macrophages - Degranulation" "Endoplasmic reticulum" "HPA062733: AB_2684853" "unprognostic (9.82e-2)" "unprognostic (4.76e-2)" "unprognostic (3.30e-2)" "unprognostic (3.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.45e-2)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (7.62e-7)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (7.78e-2)" "unprognostic (2.12e-2)" TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 55.3;Macrophages: 25.3;monocytes: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TMEM170B ENSG00000205269 "Transmembrane protein 170B" Q5T4T1 6 11537749-11583524 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.0;dendritic cells: 32.4;Excitatory neurons: 56.5;Inhibitory neurons: 51.1;Kupffer cells: 58.8;Macrophages: 34.2;monocytes: 70.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 12.4" "Breast - Adipocytes (Breast), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055134 Uncertain Approved Centrosome NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Centrosome "HPA055134: AB_2682709" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.71e-4)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (4.62e-3)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (2.45e-5)" "unprognostic (3.49e-1)" "unprognostic (1.26e-1)" "unprognostic (4.27e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-4)" "unprognostic (3.97e-2)" TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 23.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 2.9;Ionocytes: 3.7;Kupffer cells: 2.5;Proximal enterocytes: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3195.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3195.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Testis - Sertoli cells" CAB025635 Enhanced NA NA 14600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: BEWO - Unknown function" "Cluster 33: Macrophages - Degranulation" "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;Kupffer cells: 6.8;Late spermatids: 10.2;Macrophages: 4.8;monocytes: 17.9;Thymic epithelial cells: 4.9" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cancer enriched" "Detected in some" 9 "lymphoma: 55.2" "Breast - Endothelial cells, Colon - Endothelial cells" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Enhanced "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 170.2;Kupffer cells: 114.2;Langerhans cells: 304.0;Macrophages: 156.7;monocytes: 428.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cancer enriched" "Detected in some" 10 "Leukemia: 22.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favorable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favorable (8.20e-5)" "prognostic favorable (4.94e-9)" TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 53: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavorable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 33: Macrophages - Degranulation" Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favorable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favorable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favorable (4.16e-4)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 5212.6;Kupffer cells: 2893.4;Langerhans cells: 2460.5;Macrophages: 2602.8;monocytes: 3238.5;NK-cells: 1335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 53 "Leukemia: 105.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.7;tongue: 65.3" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817160-33920399 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 313.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061000, HPA074334" Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 55: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Nucleoli" Cytosol "HPA061000: AB_2684408, HPA074334: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564029-42693505 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 136.5;Inhibitory neurons: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 38.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: Non-specific - Protein binding" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" UBXN2B p37 ENSG00000215114 "UBX domain protein 2B" Q14CS0 8 58411359-58451501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.8" "Group enriched" "Detected in all" 5 "granulocytes: 42.8;monocytes: 12.9" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045278 Uncertain Approved Nucleoplasm No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA045278: AB_10963578" "unprognostic (1.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.15e-3)" "unprognostic (1.63e-1)" "unprognostic (2.22e-1)" "unprognostic (2.46e-1)" "unprognostic (8.71e-2)" "unprognostic (3.36e-1)" "unprognostic (5.97e-2)" "unprognostic (1.58e-2)" "unprognostic (1.54e-1)" "unprognostic (6.48e-3)" "unprognostic (1.26e-1)" "unprognostic (8.22e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-2)" UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699986-84779922 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 742.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 742.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: Non-specific - Unknown function" "Cluster 33: Macrophages - Degranulation" Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favorable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 176.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 297.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 33: Macrophages - Degranulation" Cytosol "Nucleoplasm, Nuclear bodies" "HPA006237: AB_1080502, HPA006428: AB_2667588, HPA071014: AB_2686333" "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 36.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 50: Non-specific - Ribosome" "Cluster 57: Non-specific - Translation" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 969.7;Granulosa cells: 1101.8;Kupffer cells: 1041.7;Macrophages: 573.9;Oligodendrocyte precursor cells: 1575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 172.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" VMA21 "MEAX, XMEA" ENSG00000160131 "Vacuolar ATPase assembly factor VMA21" Q3ZAQ7 X 151396515-151409364 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010972 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 48: Non-specific - RNA binding" "Cluster 33: Macrophages - Degranulation" "HPA010972: AB_1853034" "unprognostic (1.17e-1)" "prognostic favorable (2.30e-5)" "unprognostic (6.75e-2)" "unprognostic (9.78e-3)" "unprognostic (6.48e-2)" "unprognostic (4.68e-2)" "unprognostic (1.88e-3)" "unprognostic (4.36e-2)" "unprognostic (5.16e-2)" "unprognostic (1.74e-2)" "unprognostic (2.55e-1)" "unprognostic (8.30e-2)" "unprognostic (7.88e-2)" "unprognostic (4.17e-2)" "unprognostic (3.21e-2)" "unprognostic (3.90e-2)" "unprognostic (2.76e-1)" VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 61.1;Hofbauer cells: 26.4;Kupffer cells: 43.0;Macrophages: 37.9;monocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cancer enriched" "Detected in many" 6 "lymphoma: 24.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Testis - Macrophages, Thyroid - Neutrophils" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" VSIR "B7-H5, B7H5, C10orf54, Dies1, GI24, PD-1H, SISP1, VISTA" ENSG00000107738 "V-set immunoregulatory receptor" Q9H7M9 10 71747556-71773520 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 319.0;Extravillous trophoblasts: 339.4;Kupffer cells: 354.5;monocytes: 437.2;Syncytiotrophoblasts: 694.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1006.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007968 Approved Nucleoplasm NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA007968: AB_1845518" "unprognostic (1.19e-1)" "unprognostic (1.76e-3)" "unprognostic (1.64e-1)" "unprognostic (6.67e-2)" "unprognostic (9.29e-2)" "unprognostic (2.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (1.02e-2)" "unprognostic (6.82e-2)" "unprognostic (8.70e-2)" "unprognostic (2.57e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.37e-3)" "unprognostic (3.29e-1)" VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.2;Late spermatids: 20.2;Macrophages: 5.0;monocytes: 17.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.1" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 86.4;dendritic cells: 66.9;Hofbauer cells: 142.9;Kupffer cells: 133.6;Macrophages: 108.5;monocytes: 203.6;NK-cells: 98.3;T-cells: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Group enriched" "Detected in many" 37 "Leukemia: 64.4;lymphoma: 65.1;Myeloma: 43.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 62: Granulocytes - Innate immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" WASHC4 "KIAA1033, SWIP" ENSG00000136051 "WASH complex subunit 4" Q2M389 12 105107324-105169130 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045666, HPA046737" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 68: Kidney - Mixed function" "Cluster 33: Macrophages - Degranulation" Nucleoplasm "HPA045666: AB_2679411, HPA046737: AB_2679778" "unprognostic (2.68e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.85e-2)" "unprognostic (2.76e-1)" "unprognostic (1.10e-1)" "unprognostic (4.41e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-2)" "unprognostic (3.14e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-2)" "unprognostic (2.96e-1)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: Non-specific - Transcription" "Cluster 33: Macrophages - Degranulation" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" ZNF467 "EZI, Zfp467" ENSG00000181444 "Zinc finger protein 467" Q7Z7K2 7 149764182-149773588 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 53.9;Distal tubular cells: 34.2;Hofbauer cells: 39.6;Kupffer cells: 38.4;Muller glia cells: 68.2" "Cancer enhanced" "Detected in all" "ovarian cancer: 22.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 48.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042907 Uncertain Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 33: Macrophages - Degranulation" Mitochondria "HPA042907: AB_10966965" "unprognostic (3.01e-1)" "unprognostic (2.41e-1)" "unprognostic (6.40e-4)" "unprognostic (5.99e-2)" "unprognostic (2.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (5.14e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.25e-2)"