Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A1CF "ACF, ACF64, ACF65, APOBEC1CF, ASP" ENSG00000148584 "APOBEC1 complementation factor" Q9NQ94 10 50799409-50885675 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 144.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 154.0;Distal enterocytes: 84.8;Enteroendocrine cells: 93.9;Hepatocytes: 344.7;Intestinal goblet cells: 59.1;Paneth cells: 91.7;Proximal enterocytes: 150.9;Proximal tubular cells: 92.6" "Cancer enriched" "Detected in some" 6 "liver cancer: 18.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 5.4;Gastric cancer: 5.4;liver cancer: 20.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037779, HPA044079" Enhanced Supported Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA037779: AB_10670529, HPA044079: AB_2678800" "unprognostic (3.87e-3)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-3)" "unprognostic (2.73e-1)" "unprognostic (4.61e-3)" "unprognostic (1.71e-1)" "unprognostic (7.38e-3)" "unprognostic (1.30e-2)" "unprognostic (2.46e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-3)" "unprognostic (1.97e-2)" "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" "unprognostic (8.50e-4)" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814073-151828488 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 224.9;intestine: 241.7;liver: 946.7" "Group enriched" "Detected in many" 7 "Hepatocytes: 602.1;Proximal enterocytes: 441.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 65.8;liver cancer: 44.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.58e-6)" "prognostic unfavorable (5.02e-4)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 67.1" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Extravillous trophoblasts: 79.5;Hepatocytes: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 45.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 54: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.6;Fibroblasts: 123.0;Hepatocytes: 86.4;Inhibitory neurons: 76.1;Langerhans cells: 57.8;Microglial cells: 91.2;Schwann cells: 70.7;Theca cells: 55.3" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;lymphoma: 3.1;pancreatic cancer: 2.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 19.2;Hepatocytes: 47.3;Proximal enterocytes: 23.7;Proximal tubular cells: 45.8;Respiratory ciliated cells: 17.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.1" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2, acylglycerol lipase" P08910 15 89087459-89202355 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 276.5;Hepatocytes: 335.2;Late spermatids: 508.3;Oligodendrocyte precursor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 69.8;neutrophil: 52.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Cytosol Nucleoplasm "HPA005999: AB_1078080" "unprognostic (6.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.18e-7)" "unprognostic (4.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 325.3;Hepatocytes: 791.9;Proximal enterocytes: 428.9;Proximal tubular cells: 528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 348.6;Hepatocytes: 965.9;Proximal tubular cells: 592.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Macrophages, Skin - Sebaceous gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 360.1" "Cell type enriched" "Detected in all" 4 "Hepatocytes: 474.4" "Cancer enhanced" "Detected in all" "liver cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 56: Neurons - Neuronal signaling" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA041458: AB_2677491, HPA063555: " "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-3)" "unprognostic (1.30e-1)" "unprognostic (3.67e-1)" "prognostic favorable (3.40e-4)" "unprognostic (9.37e-3)" "prognostic favorable (6.37e-12)" "unprognostic (2.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.60e-3)" "unprognostic (7.14e-2)" ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 231.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 204.5;Basal respiratory cells: 269.8;Hepatocytes: 227.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 15: Non-specific - Protein binding" "Cluster 29: Hepatocytes - Metabolism" Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nucleoplasm, Vesicles" "HPA051772: AB_2681603" "unprognostic (1.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (1.60e-2)" "prognostic favorable (4.76e-4)" "unprognostic (2.27e-2)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "prognostic favorable (4.64e-4)" "unprognostic (8.24e-2)" "unprognostic (2.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.53e-4)" ACCS "ACS, PHACS" ENSG00000110455 "1-aminocyclopropane-1-carboxylate synthase homolog (inactive)" Q96QU6 11 44065925-44084237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018873, HPA021654" Approved Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 64: Non-specific - Transcription" "Golgi apparatus" "HPA018873: AB_1855273, HPA021654: AB_1855274" "unprognostic (3.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.98e-1)" "unprognostic (1.86e-1)" "unprognostic (7.86e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-1)" "unprognostic (7.57e-3)" "unprognostic (1.41e-1)" "unprognostic (3.38e-2)" "prognostic favorable (4.25e-4)" "unprognostic (6.51e-2)" "unprognostic (3.07e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-1)" "unprognostic (5.63e-3)" "unprognostic (1.92e-2)" ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.6;Proximal enterocytes: 30.1;Proximal tubular cells: 40.8" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.8;liver cancer: 3.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.1;liver: 178.5" "Cell type enhanced" "Detected in many" "Ductal cells: 92.3;Granulosa cells: 408.4;Proximal tubular cells: 107.2;Sertoli cells: 212.8;Theca cells: 184.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 23.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.6" "Liver - Hepatocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 17: Granulosa cells - Transcription regulation" "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favorable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favorable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 224.0" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 754.0;Hepatocytes: 4232.0;Thymic epithelial cells: 1166.4" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Endothelial cells" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 267.5;Enteroendocrine cells: 218.6;Exocrine glandular cells: 214.7;Gastric mucus-secreting cells: 676.7;Hepatocytes: 520.9;Undifferentiated cells: 308.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 54.4" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 325.3" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 737.0;Hepatocytes: 1489.3;Proximal tubular cells: 1346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 961.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 297.6" "Cancer enriched" "Detected in single" 167 "liver cancer: 62.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017006, HPA052437" Enhanced Uncertain "Plasma membrane" "Secreted to blood" NA NA 54900000000 8700000000 "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Plasma membrane" "HPA017006: AB_1844635, HPA052437: AB_2732575" "prognostic favorable (1.80e-4)" "unprognostic (5.73e-2)" "unprognostic (4.24e-2)" AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 75.3;Oligodendrocyte precursor cells: 32.3;Oligodendrocytes: 36.3;Proximal enterocytes: 25.9;Proximal tubular cells: 16.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 10.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 369.3;liver: 445.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 583.0;Late spermatids: 406.6;Paneth cells: 454.1;Proximal enterocytes: 1318.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019544 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 154.1;Langerhans cells: 272.4;Schwann cells: 259.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Nucleoplasm "CAB005072: AB_633731, HPA029722: AB_10599189, HPA029723: AB_10599025" "unprognostic (1.29e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (4.32e-2)" "unprognostic (9.98e-2)" "unprognostic (1.24e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-2)" "unprognostic (9.45e-2)" AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.8;Basal respiratory cells: 234.6;Basal squamous epithelial cells: 354.3;Cholangiocytes: 231.0;Hepatocytes: 763.5" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 5 "Bladder cancer: 255.2;Esophageal cancer: 521.6;Gallbladder cancer: 849.0;Kidney cancer: 272.4;liver cancer: 827.9;lung cancer: 296.7" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.5;Basal respiratory cells: 145.1;Club cells: 133.3;Hepatocytes: 477.6;Squamous epithelial cells: 116.6" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 1225.3;Gallbladder cancer: 1163.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" AL121845.2 ENSG00000273047 "Novel transcript, LIME1-SLC2A4RG readthrough" 20 63738270-63740398 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "liver: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.0" "Group enriched" "Detected in many" 31 "dendritic cells: 6.0;T-cells: 4.2" "Not detected" "Not detected" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "unprognostic (3.96e-2)" "unprognostic (1.60e-1)" AL163636.1 ENSG00000259171 "Novel protein, ANG-RNASE4 readthrough" 14 20684587-20700576 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 115.1" "Cell type enriched" "Detected in single" 5 "Gastric mucus-secreting cells: 2.4" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 9.9;memory B-cell: 3.6;myeloid DC: 5.8" "Group enriched" "Detected in many" 12 "B-cells: 3.6;dendritic cells: 5.8;monocytes: 9.9" "Low cancer specificity" "Detected in many" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 61: Non-specific - Transcription" "unprognostic (1.88e-1)" "unprognostic (3.10e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-3)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "unprognostic (8.66e-2)" "unprognostic (6.61e-2)" "unprognostic (6.87e-3)" "unprognostic (8.58e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-2)" "unprognostic (5.11e-2)" ALAS1 "ALAS, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 720.5;liver: 548.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.0;Hepatocytes: 270.9;Syncytiotrophoblasts: 364.9;Theca cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 233.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 233.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria Nucleoplasm "CAB017498: AB_2225629, HPA035860: AB_10672992" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.98e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (5.64e-2)" "prognostic favorable (6.06e-7)" "unprognostic (8.45e-2)" "unprognostic (3.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 667.2;Leydig cells: 411.1;Proximal tubular cells: 388.8;Respiratory ciliated cells: 489.4" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cancer enhanced" "Detected in many" "liver cancer: 1072.2;Rhabdoid: 926.6;Sarcoma: 887.0" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 67.4;Ductal cells: 57.9;Hepatocytes: 116.1;Proximal tubular cells: 171.4;Theca cells: 66.7;Undifferentiated cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" ALDH8A1 ALDH12 ENSG00000118514 "Aldehyde dehydrogenase 8 family member A1" Q9H2A2 6 134917393-134950115 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "kidney: 72.2;liver: 247.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 33.5;Hepatocytes: 139.0;Proximal tubular cells: 116.5;Thymic epithelial cells: 54.5" "Group enriched" "Detected in some" 7 "liver cancer: 26.3;renal cancer: 17.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 8 "Rhabdoid: 14.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA026292, HPA055414" Enhanced Approved Nucleoplasm,Centrosome NA NA 110000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 60: Proximal tubular cells - Absorption" Centrosome Nucleoplasm "HPA026292: AB_1844741, HPA055414: AB_2682810" "unprognostic (1.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "unprognostic (1.75e-1)" "unprognostic (2.70e-2)" "unprognostic (6.32e-2)" "unprognostic (4.30e-3)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "prognostic favorable (9.87e-4)" "unprognostic (1.25e-2)" "unprognostic (1.36e-1)" "unprognostic (2.36e-2)" "unprognostic (5.86e-5)" ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 17 "Hepatocytes: 702.9;Proximal tubular cells: 212.1" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 39 "liver cancer: 10.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 710.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 322.2;NK-cells: 230.9;Syncytiotrophoblasts: 844.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 19248.5" "Group enriched" "Detected in many" 13 "Hepatocytes: 24470.7;Proximal enterocytes: 13007.5" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 13 "Gastric cancer: 203.3;liver cancer: 529.2" "Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" NA NA 1450000000000 110000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 7 "Hepatocytes: 2317.4;Proximal enterocytes: 1362.5" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "liver cancer: 176.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 108.5;Endometrial ciliated cells: 115.5;Glandular and luminal cells: 222.6;Hepatocytes: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 337.3" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 14: Endometrium - Transcription regulation" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 111.7;NK-cells: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 85: Liver - Metabolism" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: AB_10670037, HPA029167: AB_10670832" "unprognostic (7.25e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-2)" "unprognostic (8.29e-2)" "unprognostic (3.76e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.46e-1)" "unprognostic (6.65e-3)" "unprognostic (2.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "prognostic favorable (6.61e-4)" APOM "G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 390.7" "Group enriched" "Detected in many" 7 "Hepatocytes: 711.7;Proximal tubular cells: 406.4" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "liver cancer: 7.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 7400000000 8200000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.7;Granulosa cells: 102.3;Hepatocytes: 247.1;Prostatic glandular cells: 470.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "prostate cancer: 92.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 73: Prostatic glandular cells - Transcription" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 80.0;Intestinal goblet cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 15: Smooth muscle cells - Muscle contraction" "Golgi apparatus, Vesicles, Cytosol" "HPA026426: AB_10599487, HPA026440: AB_10599422, HPA028115: AB_10602285" "unprognostic (4.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "prognostic favorable (8.13e-5)" "unprognostic (3.61e-2)" "unprognostic (7.90e-2)" "unprognostic (2.10e-2)" "unprognostic (1.75e-3)" "unprognostic (1.94e-3)" "unprognostic (5.83e-2)" "prognostic favorable (5.65e-4)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (8.17e-2)" "unprognostic (5.21e-3)" ARL5B ARL8 ENSG00000165997 "ADP ribosylation factor like GTPase 5B" Q96KC2 10 18659431-18681639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 308.9;Langerhans cells: 365.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 14: Endometrium - Transcription regulation" "HPA027002: AB_10601685" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (4.04e-2)" "unprognostic (4.32e-2)" "unprognostic (1.77e-2)" "unprognostic (7.86e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "unprognostic (8.34e-2)" "unprognostic (6.54e-2)" "unprognostic (1.83e-1)" "unprognostic (7.54e-2)" "unprognostic (2.62e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.5;Endothelial cells: 16.7;Erythroid cells: 36.5;Fibroblasts: 8.3;Hepatocytes: 27.6;Rod photoreceptor cells: 12.9" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 11.3" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 66: Endothelial cells - Angiogenesis" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 396.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.0;Hepatocytes: 514.1;Proximal enterocytes: 271.8;Proximal tubular cells: 223.4" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085686-104115582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.4;liver: 151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.9;Distal enterocytes: 25.5;Granulosa cells: 65.4;Hepatocytes: 76.4;Proximal tubular cells: 45.5;Suprabasal keratinocytes: 64.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA069761 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 3: Suprabasal keratinocytes - Cornification" "HPA069761: AB_2686191" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 60.0;Spermatocytes: 69.4" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 14: Bone cancer - Transcription" "Cluster 32: Neurons - Synaptic function" "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 22.9;Hepatocytes: 49.8;Sertoli cells: 27.6;Smooth muscle cells: 108.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.0;Myeloma: 2.7;Neuroblastoma: 1.1;prostate cancer: 1.2" "Breast - Endothelial cells, Liver - Hepatocytes" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 72: Smooth muscle cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell type enhanced" "Detected in all" "Astrocytes: 287.2;Early spermatids: 153.6;Oligodendrocytes: 96.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria "Intracellular and membrane" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 63: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: AB_10696054, HPA031956: " "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (9.37e-3)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.32e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "prognostic favorable (5.54e-9)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (1.49e-2)" BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.7;Hepatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 454.0;Fibroblasts: 688.8;Hepatocytes: 1166.1;Leydig cells: 1154.2;Peritubular cells: 402.2;Thymic epithelial cells: 590.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 79.0" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 112.1;Leydig cells: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011338, CAB026172" Supported "Secreted to blood" NA NA 5500000000 15000000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 29: Hepatocytes - Metabolism" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Group enriched" "Detected in some" 4 "Hepatocytes: 6.9;Thymic epithelial cells: 8.7" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 7.2;Myeloma: 7.8" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.5;liver: 385.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Hepatocytes: 7.2;Kupffer cells: 3.0;Plasma cells: 1.9;Thymic epithelial cells: 13.9" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.1;Myeloma: 4.1" "Liver - Hepatocytes" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" NA NA 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" CAPN12 ENSG00000182472 "Calpain 12" Q6ZSI9 19 38730187-38769904 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 22.8;liver: 24.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.3;NK-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "basophil: 59.3;NK-cell: 25.5" "Group enriched" "Detected in many" 9 "granulocytes: 59.3;NK-cells: 25.5" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 3.0" HPA053322 Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 7: NK-cells - Immune response regulation" "Focal adhesion sites" Nucleoplasm "HPA053322: AB_2682111" "unprognostic (1.81e-1)" "unprognostic (4.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-3)" "unprognostic (7.20e-2)" "unprognostic (2.45e-2)" "unprognostic (1.29e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (5.90e-6)" "unprognostic (7.04e-2)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (4.59e-2)" CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1217.3" "Cell type enhanced" "Detected in all" "Erythroid cells: 448.6;Hepatocytes: 440.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4736.8" "Lineage enriched" "Detected in all" 13 "granulocytes: 4736.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 760000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 71: Erythroid cells - Oxygen transport" Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favorable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" CBSL ENSG00000274276 "Cystathionine beta-synthase like" P0DN79 21 6444869-6468040 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 88.1;pancreas: 48.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Low cancer specificity" "Detected in many" HPA001223 Supported Approved Nucleoli,Vesicles NA NA 510000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (2.39e-1)" "unprognostic (1.54e-2)" "unprognostic (1.15e-1)" "unprognostic (4.78e-3)" "unprognostic (6.49e-2)" "unprognostic (1.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.62e-3)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (3.17e-3)" "unprognostic (8.44e-2)" "unprognostic (2.46e-1)" "unprognostic (3.61e-1)" CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 83.2;Serous glandular cells: 61.1;Thymic epithelial cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2969.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 69: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 317.5;Kupffer cells: 276.3;Langerhans cells: 130.6;Macrophages: 206.1;monocytes: 167.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 33: Macrophages - Degranulation" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.2;Hepatocytes: 94.3;Hofbauer cells: 80.3;Suprabasal keratinocytes: 104.7;Syncytiotrophoblasts: 231.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cancer enhanced" "Detected in many" "Leukemia: 72.2;liver cancer: 58.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" CEBPB "C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5" ENSG00000172216 "CCAAT enhancer binding protein beta" P17676 20 50190830-50192668 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 1024.4;Syncytiotrophoblasts: 1559.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.7" "Group enriched" "Detected in many" 8 "granulocytes: 16.7;monocytes: 7.7" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB004213, HPA061355, HPA062267" Supported Enhanced Nucleoplasm Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "CAB004213: AB_626772, HPA061355: AB_2684487, HPA062267: AB_2684731" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.24e-2)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.40e-3)" "unprognostic (1.79e-2)" "unprognostic (9.85e-3)" "unprognostic (9.26e-3)" "unprognostic (6.55e-2)" "prognostic unfavorable (2.44e-12)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-2)" "unprognostic (7.63e-2)" CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 361.6;Hepatocytes: 844.7;Leydig cells: 290.7;Thymic epithelial cells: 395.1" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 78.4" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 65: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 109.7;Hepatocytes: 459.9;Muller glia cells: 116.0;Proximal tubular cells: 197.0" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 29: Hepatocytes - Metabolism" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 28.8;Excitatory neurons: 27.8;Fibroblasts: 15.6;Hepatocytes: 25.4;Horizontal cells: 15.4;Inhibitory neurons: 36.8;Smooth muscle cells: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" CIDEB ENSG00000136305 "Cell death inducing DFFA like effector b" Q9UHD4 14 24305096-24311430 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 310.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 245.1;Proximal enterocytes: 291.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 6.5;Myeloma: 6.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001272, HPA059646" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus, Vesicles" "HPA001272: AB_2666255, HPA059646: " "unprognostic (2.62e-2)" "unprognostic (6.55e-2)" "unprognostic (2.62e-3)" "unprognostic (9.35e-2)" "unprognostic (2.38e-3)" "unprognostic (1.83e-2)" "unprognostic (1.57e-1)" "unprognostic (8.48e-4)" "unprognostic (1.36e-1)" "unprognostic (3.06e-2)" "unprognostic (3.39e-3)" "unprognostic (2.36e-2)" "unprognostic (6.43e-2)" "unprognostic (6.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.09e-2)" "unprognostic (2.64e-1)" CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 309.8;skin 1: 288.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 275.1;Basal prostatic cells: 242.9;Basal respiratory cells: 212.0;Basal squamous epithelial cells: 211.0;Ductal cells: 201.0;Salivary duct cells: 241.9;Squamous epithelial cells: 294.6;Suprabasal keratinocytes: 483.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 25.4" "CAB002602, HPA048319" Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "kidney: 13.8;liver: 39.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.8;Distal tubular cells: 9.3;Ductal cells: 11.8;Exocrine glandular cells: 7.5;Glandular and luminal cells: 4.7;Hepatocytes: 18.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.1" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054707 Uncertain Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 74: Pancreatic cells - Mixed function" Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 89.4;Spermatocytes: 83.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 64: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 206.8;Microglial cells: 342.1;Rod photoreceptor cells: 208.9;Syncytiotrophoblasts: 382.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.4;plasmacytoid DC: 8.1" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.1" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 62: B-cells - B-cell activation" "Cell Junctions" "HPA044933: AB_2679148, HPA053344: AB_2682123" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.38e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.27e-13)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "unprognostic (1.42e-1)" COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 375.8;Smooth muscle cells: 250.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Fibroblast_1" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 72: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" COLEC10 CL-L1 ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 65.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.8;Excitatory neurons: 6.8;Inhibitory neurons: 5.3;Kupffer cells: 3.0;Oligodendrocyte precursor cells: 2.4;Oligodendrocytes: 4.5" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 9.9;Neuroblastoma: 10.2" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 30000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 23.8;Fibroblasts: 25.4;Peritubular cells: 55.6;Proximal tubular cells: 90.1;Sertoli cells: 33.2;Smooth muscle cells: 26.0;Theca cells: 96.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 25.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 53: Connective tissue cells - ECM organization" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" CPS1 ENSG00000021826 "Carbamoyl-phosphate synthase 1" P31327 2 210477682-210679107 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Urea cycle" "Allosteric enzyme, Ligase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1063.2" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 1781.9" "Cancer enriched" "Detected in many" 8 "liver cancer: 136.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 126.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003781, HPA021400" Enhanced Supported "Nucleoli,Nucleoli rim" NA NA 8300000 "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoli, Nucleoli rim" "CAB003781: , HPA021400: AB_1847197" "unprognostic (1.67e-2)" "unprognostic (3.72e-2)" "unprognostic (4.02e-2)" "unprognostic (7.21e-7)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "prognostic favorable (6.93e-5)" "unprognostic (1.23e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-2)" "unprognostic (5.38e-2)" "unprognostic (1.94e-3)" "unprognostic (2.38e-4)" "unprognostic (5.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.14e-2)" "unprognostic (3.74e-2)" CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Cell type enhanced" "Detected in some" "Adipocytes: 104.1;Endothelial cells: 76.6;Fibroblasts: 199.8;Granulosa cells: 439.7;Kupffer cells: 91.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Brain cancer: 14.3" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039487, HPA079296" Approved Approved "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 64: Non-specific - Transcription" "Endoplasmic reticulum, Vesicles, Plasma membrane" "HPA039487: AB_10672776, HPA079296: " "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm "HPA062654: AB_2684819" "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 16.2" "Heart muscle - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 65: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 509.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1381.2;Basal respiratory cells: 3144.8;Glandular and luminal cells: 1317.6;Ionocytes: 2384.1;Langerhans cells: 2569.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2071.3;Distal tubular cells: 1530.0;Hepatocytes: 3995.8;Proximal enterocytes: 1932.9;Proximal tubular cells: 2784.8" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.1;urinary bladder: 63.6" "Cell type enhanced" "Detected in some" "Adipocytes: 15.4;Endometrial ciliated cells: 2.7;Endothelial cells: 2.8;Glandular and luminal cells: 5.6;Hepatocytes: 10.0" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 52.7;Esophageal cancer: 91.2" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 367.9;Hofbauer cells: 149.1;Proximal enterocytes: 197.5" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cancer enhanced" "Detected in many" "liver cancer: 32.5;skin cancer: 61.9" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 19: Macrophages - Innate immune response" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 54.8;Proximal enterocytes: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 55.7;Late spermatids: 20.2;Prostatic glandular cells: 30.7;Serous glandular cells: 23.6" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 59 "Hepatocytes: 2605.9;Proximal enterocytes: 1368.9" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.4;Early spermatids: 5.7;Excitatory neurons: 3.9;Hepatocytes: 3.8;Inhibitory neurons: 1.9;Late spermatids: 4.7;Spermatocytes: 2.2" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 36: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.7" "Group enriched" "Detected in some" 4 "Cholangiocytes: 3.8;Hepatocytes: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 52: Spermatids - Smell perception" "Cluster 29: Hepatocytes - Metabolism" Cytosol Vesicles "HPA072245: , HPA075539: " CYP4A11 "CYP4A2, CYP4AII" ENSG00000187048 "Cytochrome P450 family 4 subfamily A member 11" Q02928 1 46929177-46941484 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 333 "kidney: 218.8;liver: 857.1" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 454.5" "Cancer enriched" "Detected in some" 5 "liver cancer: 73.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (9.05e-2)" "unprognostic (4.98e-2)" "unprognostic (4.43e-2)" "unprognostic (4.11e-1)" "unprognostic (7.81e-5)" "unprognostic (5.10e-3)" "unprognostic (1.16e-2)" "unprognostic (1.83e-2)" "unprognostic (1.92e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (4.59e-2)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (3.00e-3)" "unprognostic (1.68e-2)" CYP4A22 ENSG00000162365 "Cytochrome P450 family 4 subfamily A member 22" Q5TCH4 1 47137435-47149735 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 214.2" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 98.8" "Cancer enriched" "Detected in some" 13 "liver cancer: 20.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" NA NA "Cluster 85: Liver - Metabolism" "Cluster 42: Sarcoma - Muscle contraction" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-2)" "unprognostic (2.88e-3)" "unprognostic (2.76e-3)" "unprognostic (1.50e-3)" "unprognostic (2.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-2)" "unprognostic (5.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.71e-1)" "unprognostic (8.59e-4)" CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.9;liver: 72.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 57.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 213.3" "Liver - Hepatocytes" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 68: Muller glia cells - Visual perception" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" DCPS "HINT-5, HINT5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126304060-126350005 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.7" "Cell type enhanced" "Detected in all" "Plasma cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 46.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Supported Supported Nucleoplasm,Cytosol NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA039632: AB_10794200, HPA058597: AB_2683770" "unprognostic (1.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (5.57e-2)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "unprognostic (5.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.24e-2)" "unprognostic (8.04e-2)" "unprognostic (7.67e-2)" "unprognostic (3.40e-2)" DCXR "DCR, HCR2, KIDCR, P34H, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 1851.6" "Group enriched" "Detected in all" 5 "Hepatocytes: 4195.4;Proximal tubular cells: 2667.7" "Group enriched" "Detected in all" 5 "liver cancer: 305.9;prostate cancer: 163.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Uncertain Nucleoli,Microtubules NA NA 4000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 17: RS4;11 - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoli, Microtubules" "HPA023371: AB_1847530, HPA023863: AB_1847531" "unprognostic (3.33e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-1)" "unprognostic (1.16e-2)" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (4.54e-3)" "unprognostic (1.86e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-2)" "prognostic favorable (4.70e-4)" "unprognostic (1.72e-1)" "prognostic favorable (2.13e-4)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.10e-2)" DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23979828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 835.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 265.5;Hepatocytes: 399.7;Proximal enterocytes: 406.5;Proximal tubular cells: 204.1;Undifferentiated cells: 208.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "HPA049871, HPA074115" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" DDTL ENSG00000099974 "D-dopachrome tautomerase like" A6NHG4 22 23966888-23972556 "Predicted intracellular proteins" Lyase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 58.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 6.5;Proximal enterocytes: 7.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA074115 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 52: Spermatids - Smell perception" "Cluster 61: Non-specific - Transcription" "HPA074115: " "unprognostic (6.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (6.34e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "prognostic favorable (5.98e-4)" "unprognostic (2.65e-2)" "unprognostic (2.26e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-2)" "unprognostic (2.18e-1)" "unprognostic (5.74e-2)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (3.70e-2)" "unprognostic (3.58e-3)" DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 165.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.8;Proximal enterocytes: 78.0;Proximal tubular cells: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 8: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes Microtubules "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 105.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 36: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 323.7" "Cell type enhanced" "Detected in many" "Late spermatids: 401.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 86.8;MAIT T-cell: 63.1;memory CD4 T-cell: 46.9;memory CD8 T-cell: 41.0;myeloid DC: 24.0;naive CD4 T-cell: 79.2;naive CD8 T-cell: 50.1;NK-cell: 41.1" "Group enriched" "Detected in many" 5 "dendritic cells: 24.0;NK-cells: 41.1;T-cells: 86.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favorable (2.65e-4)" "unprognostic (5.48e-2)" DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 206.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617" "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 24.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.3;Distal enterocytes: 31.8;Enteroendocrine cells: 33.0;Hepatocytes: 38.5;Intestinal goblet cells: 31.8;Paneth cells: 34.1;Proximal enterocytes: 56.8;Thymic epithelial cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" DNAJC25 bA16L21.2.1 ENSG00000059769 "DnaJ heat shock protein family (Hsp40) member C25" Q9H1X3 9 111631334-111654351 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 32.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 74.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA019122 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 55: Non-specific - Unknown function" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm Cytosol "HPA019122: AB_1853155" "unprognostic (3.07e-1)" "unprognostic (7.42e-2)" "unprognostic (8.94e-3)" "prognostic favorable (3.73e-4)" "unprognostic (2.08e-2)" "unprognostic (5.66e-2)" "unprognostic (1.60e-2)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (9.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.09e-2)" "unprognostic (2.52e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-1)" "unprognostic (8.30e-2)" "unprognostic (5.19e-2)" DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1616.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 199.6;liver: 477.6" "Group enriched" "Detected in some" 8 "Hepatocytes: 398.4;Proximal tubular cells: 376.8;Thymic epithelial cells: 161.5" "Cancer enriched" "Detected in some" 5 "liver cancer: 57.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.2" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024785, HPA070814" Enhanced NA NA 820000 "Cluster 85: Liver - Metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 60: Proximal tubular cells - Absorption" "HPA024785: AB_1847856, HPA070814: " "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 38000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 38: Non-specific - mRNA processing" "Cluster 16: Non-specific - RNA binding" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: AB_1847954, HPA028277: AB_10603664" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.03e-2)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (7.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.24e-3)" "unprognostic (7.11e-2)" "unprognostic (1.64e-3)" "unprognostic (4.10e-3)" "unprognostic (3.04e-3)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-2)" EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 641.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 48: Non-specific - RNA binding" "Cluster 29: Hepatocytes - Metabolism" "Nuclear membrane, Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 303.3;Suprabasal keratinocytes: 273.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 13: Non-specific - Nuclear processes" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" ECHDC2 FLJ10948 ENSG00000121310 "Enoyl-CoA hydratase domain containing 2" Q86YB7 1 52895910-52927212 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 174.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 835.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026731, HPA026768" Enhanced Approved Mitochondria NA NA 240000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA026731: AB_1847969, HPA026768: AB_1847970" "unprognostic (2.73e-3)" "unprognostic (1.52e-2)" "unprognostic (4.08e-2)" "unprognostic (3.76e-1)" "unprognostic (7.67e-2)" "prognostic favorable (6.65e-4)" "unprognostic (1.51e-3)" "unprognostic (1.40e-3)" "unprognostic (6.11e-2)" "unprognostic (7.16e-2)" "unprognostic (2.98e-3)" "unprognostic (4.40e-2)" "unprognostic (5.47e-2)" "unprognostic (5.12e-2)" "unprognostic (2.93e-1)" "unprognostic (3.62e-1)" "prognostic favorable (2.70e-4)" ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase" "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1644.1;Proximal tubular cells: 2051.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 57.3;Hepatocytes: 47.5;Leydig cells: 123.8;Peritubular cells: 72.2;Smooth muscle cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.1" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 1145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 54: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 197.1;Excitatory neurons: 258.6;Inhibitory neurons: 239.6;Late spermatids: 515.8;Oligodendrocyte precursor cells: 217.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 36: Spermatids - Spermatogenesis" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 280.2;Kupffer cells: 55.9;Proximal tubular cells: 126.7" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 29: Hepatocytes - Metabolism" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 47.2" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 16.9;Hepatocytes: 18.7" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" NA NA 12300 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 26: Intestinal epithelial cells - Absorption" "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" ERLIN1 "C10orf69, Erlin-1, KE04, SPFH1, SPG62" ENSG00000107566 "ER lipid raft associated 1" O75477 10 100150094-100186033 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 68.9;Hepatocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA011252 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 54: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA011252: AB_1853965" "unprognostic (3.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (2.69e-1)" "unprognostic (1.70e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (7.63e-4)" "unprognostic (1.26e-1)" "unprognostic (9.68e-2)" "unprognostic (1.99e-3)" "unprognostic (9.09e-2)" "unprognostic (1.32e-3)" "unprognostic (6.10e-3)" "unprognostic (1.76e-1)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 566.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 13: Non-specific - Nuclear processes" "Cluster 18: Non-specific - Mixed function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" ETNK2 "EKI2, FLJ10761" ENSG00000143845 "Ethanolamine kinase 2" Q9NVF9 1 204131062-204152044 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 108.1;liver: 235.5;testis: 125.0" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1397.0" "Cancer enhanced" "Detected in all" "liver cancer: 32.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "breast cancer: 44.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 8 "basal ganglia: 22.6" HPA057167 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" "HPA057167: AB_2683358" "unprognostic (1.64e-1)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-3)" "unprognostic (4.28e-2)" "unprognostic (6.54e-2)" "unprognostic (4.35e-2)" "prognostic favorable (6.50e-4)" "unprognostic (5.50e-3)" "unprognostic (4.69e-2)" "unprognostic (2.00e-2)" "unprognostic (1.20e-1)" EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.2;Alveolar cells type 2: 47.2;Cytotrophoblasts: 42.0;Hepatocytes: 66.3;Proximal tubular cells: 58.2;Syncytiotrophoblasts: 155.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 77.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 99.5;Hepatocytes: 172.8;Leydig cells: 221.9;Peritubular cells: 237.0" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "liver cancer: 18.0" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 70.0" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.1" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 310.6;Proximal tubular cells: 255.0" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" FAHD2A CGI-105 ENSG00000115042 "Fumarylacetoacetate hydrolase domain containing 2A" Q96GK7 2 95402708-95416616 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042145, HPA044987, CAB045971, CAB045972" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 59: Proximal enterocytes - Transmembrane transport" "CAB045971: AB_11126570, CAB045972: AB_11140511, HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.52e-2)" "unprognostic (1.25e-3)" "unprognostic (9.36e-2)" "unprognostic (1.27e-2)" "unprognostic (7.77e-3)" "unprognostic (6.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (4.58e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-2)" "unprognostic (1.17e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-2)" "unprognostic (1.55e-2)" FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 68.8;Hepatocytes: 56.7;Hofbauer cells: 81.8;Late spermatids: 200.6;Serous glandular cells: 86.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 21: Serous glandular cells - Salivary secretion" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" FAM8A1 AHCP ENSG00000137414 "Family with sequence similarity 8 member A1" Q9UBU6 6 17600302-17611715 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 622.1;Late spermatids: 364.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044698, HPA073675" Approved Approved "Golgi apparatus" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 15: Non-specific - Protein binding" "Cluster 49: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA044698: AB_2679051, HPA073675: AB_2732236" "unprognostic (4.06e-1)" "unprognostic (2.32e-1)" "unprognostic (9.11e-2)" "unprognostic (6.90e-2)" "unprognostic (1.99e-2)" "unprognostic (5.17e-3)" "unprognostic (6.13e-2)" "unprognostic (1.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.09e-3)" "unprognostic (4.44e-2)" "unprognostic (3.50e-1)" "unprognostic (1.56e-2)" "unprognostic (3.85e-2)" "unprognostic (3.71e-1)" "unprognostic (7.59e-2)" "unprognostic (2.98e-1)" FANCC "FA3, FAC, FACC" ENSG00000158169 "FA complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 128.6;Hepatocytes: 39.0;Late spermatids: 131.5;Microglial cells: 48.3;Oligodendrocytes: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 8.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.8" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 55: Non-specific - Unknown function" "Cluster 49: Early spermatids - Spermatogenesis" Nucleoplasm "CAB017793: , HPA030771: AB_2673604" "unprognostic (1.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "unprognostic (8.00e-3)" "unprognostic (3.19e-2)" "prognostic favorable (6.03e-6)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.71e-2)" FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 1: T-cells - Immune response" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" FBXO17 "FBG4, Fbx17, FBXO26, FLJ11798, FLJ25205, MGC9379" ENSG00000269190 "F-box protein 17" Q96EF6 19 38941401-38975742 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 51.1;Leydig cells: 84.6;Peritubular cells: 75.9;Proximal tubular cells: 69.5" "Cancer enhanced" "Detected in many" "renal cancer: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (6.97e-3)" "prognostic unfavorable (5.67e-4)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (4.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.71e-3)" "unprognostic (1.91e-2)" "unprognostic (1.83e-3)" "prognostic unfavorable (5.91e-4)" "unprognostic (5.34e-2)" "unprognostic (4.06e-4)" "unprognostic (2.77e-3)" FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Group enriched" "Detected in some" 10 "Endothelial cells: 77.4;Fibroblasts: 196.9;Kupffer cells: 94.7" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 4163.9" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 7130.1" "Cancer enriched" "Detected in some" 40 "liver cancer: 399.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "liver cancer: 59.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 57000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (1.75e-5)" "unprognostic (3.00e-1)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (2.15e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.86e-7)" "prognostic unfavorable (5.38e-4)" "unprognostic (3.62e-1)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 89.6;Cholangiocytes: 123.2;Hepatocytes: 248.3;Intestinal goblet cells: 58.1;Proximal enterocytes: 94.8;Proximal tubular cells: 62.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" FRRS1 "SDFR2, SDR2" ENSG00000156869 "Ferric chelate reductase 1" Q6ZNA5 1 99703970-99766635 "Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.8;Hepatocytes: 46.0;Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "eosinophil: 12.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 12.6" "Cancer enriched" "Detected in all" 8 "Gallbladder cancer: 78.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017883 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA017883: AB_2294223" "unprognostic (3.97e-2)" "unprognostic (8.02e-2)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (8.54e-3)" "unprognostic (7.00e-2)" "unprognostic (2.64e-1)" "unprognostic (8.25e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (2.65e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (3.54e-2)" FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Group enriched" "Detected in many" 6 "Granulosa cells: 676.3;Skeletal myocytes: 213.8" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.5" "Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 17: Granulosa cells - Transcription regulation" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 939.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 107.8;Early spermatids: 105.2;Hepatocytes: 369.0;Late spermatids: 125.9;Proximal tubular cells: 315.4" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 1600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favorable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 629.4;Hofbauer cells: 179.1;Proximal enterocytes: 746.5;Proximal tubular cells: 328.9" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 305.6;salivary gland: 220.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 109.3;Hepatocytes: 114.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 130000 "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 21: Serous glandular cells - Salivary secretion" "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" G6PC "G6PC1, G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit" P35575 17 42900797-42914438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 75.1;liver: 286.7" "Group enriched" "Detected in some" 8 "Hepatocytes: 233.9;Proximal enterocytes: 170.1" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "liver cancer: 2.5" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052324 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA052324: AB_2681790" "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favorable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favorable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" GADD45G "CR6, DDIT2, GADD45gamma, GRP17" ENSG00000130222 "Growth arrest and DNA damage inducible gamma" O95257 9 89605012-89606555 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 317.8;liver: 366.0" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 1722.1" "Cancer enhanced" "Detected in all" "prostate cancer: 79.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 4.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 4.9" "Cancer enhanced" "Detected in many" "prostate cancer: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023606 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA023606: AB_1849409" "unprognostic (5.84e-2)" "unprognostic (1.61e-2)" "unprognostic (1.08e-2)" "prognostic favorable (7.06e-4)" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.77e-3)" "unprognostic (3.75e-2)" "unprognostic (7.65e-3)" "unprognostic (4.16e-3)" "prognostic favorable (3.80e-5)" "unprognostic (1.11e-1)" "unprognostic (1.63e-2)" "unprognostic (4.95e-1)" "unprognostic (3.88e-2)" "unprognostic (3.41e-1)" "unprognostic (1.22e-1)" GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 126.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 120.2;Hepatocytes: 125.3;Proximal enterocytes: 141.2" "Cancer enhanced" "Detected in all" "liver cancer: 42.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" NA NA 57000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 17: RS4;11 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "Golgi apparatus" "HPA007094: AB_1078939, HPA016960: AB_1849430" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (3.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.62e-5)" GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol NA NA 260000 "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: RS4;11 - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favorable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favorable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in many" 4 "Astrocytes: 38.6;Early spermatids: 66.5;Excitatory neurons: 113.3;Inhibitory neurons: 139.1;Late spermatids: 84.4;Oligodendrocytes: 79.2" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Myeloma: 63.1" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "kidney: 50.0;liver: 169.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 56.9" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 29: Hepatocytes - Metabolism" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 350.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 859.3;Hofbauer cells: 490.1;Proximal enterocytes: 617.2;Proximal tubular cells: 401.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 170000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 19: Macrophages - Innate immune response" Nucleoplasm "HPA046258: AB_10967205" "unprognostic (2.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (9.89e-3)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "prognostic favorable (5.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.67e-1)" "unprognostic (3.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.03e-3)" "unprognostic (9.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.55e-1)" GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 418.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 1: T-cells - Immune response" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.2;Hepatocytes: 121.3;Inhibitory neurons: 113.4;Oligodendrocyte precursor cells: 173.3" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 204.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.7;Hepatocytes: 51.0;Inhibitory neurons: 30.8" "Cancer enriched" "Detected in single" 4 "liver cancer: 1.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 10 "Hepatocytes: 155.3;Proximal enterocytes: 50.9;Proximal tubular cells: 120.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 576.3" "Group enriched" "Detected in some" 9 "Hepatocytes: 291.4;Proximal tubular cells: 522.1" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "prostate cancer: 59.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" GLYATL3 "bA28H17.2, C6orf140" ENSG00000203972 "Glycine-N-acyltransferase like 3" Q5SZD4 6 49499923-49528078 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.2" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.1;Enteroendocrine cells: 1.8;Glandular and luminal cells: 1.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.7;lung cancer: 1.9;prostate cancer: 2.0" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA044044 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 14: Endometrium - Transcription regulation" "HPA044044: AB_10960855" "unprognostic (3.57e-1)" "unprognostic (6.85e-2)" GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 48.4;liver: 90.5;salivary gland: 55.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 58.2;Hepatocytes: 102.0;Intestinal goblet cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" GNPNAT1 "FLJ10607, Gpnat1" ENSG00000100522 "Glucosamine-phosphate N-acetyltransferase 1" Q96EK6 14 52775193-52791668 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 81.0;Hepatocytes: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044647 Approved NA NA 72000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "HPA044647: AB_10795986" "unprognostic (4.55e-3)" "unprognostic (1.19e-2)" "unprognostic (4.47e-3)" "unprognostic (5.18e-3)" "unprognostic (4.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (3.19e-3)" "unprognostic (1.03e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (8.52e-5)" "unprognostic (5.82e-2)" "unprognostic (3.22e-3)" "unprognostic (2.16e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (4.05e-2)" GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 129.0;Proximal enterocytes: 216.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 35.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.2;Excitatory neurons: 329.3;Inhibitory neurons: 484.6;Oligodendrocyte precursor cells: 662.3;Rod photoreceptor cells: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 37.9;testis cancer: 39.5" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013601, HPA017671" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 37: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles" "HPA013601: , HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 46.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.0;Excitatory neurons: 61.6;Hepatocytes: 81.5;Inhibitory neurons: 76.5;Oligodendrocyte precursor cells: 31.8" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 6.0" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3100000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 29: Hepatocytes - Metabolism" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 193.3;Paneth cells: 64.5;Proximal enterocytes: 137.1;Proximal tubular cells: 153.1" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" GRAMD4 "DIP, KIAA0767" ENSG00000075240 "GRAM domain containing 4" Q6IC98 22 46576012-46679790 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.2" "Cell type enhanced" "Detected in many" "Astrocytes: 43.7;dendritic cells: 45.1;Distal enterocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "unprognostic (8.67e-3)" "unprognostic (1.78e-3)" "unprognostic (2.19e-2)" "unprognostic (8.11e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.04e-4)" "unprognostic (1.08e-1)" "unprognostic (7.07e-2)" "unprognostic (5.72e-2)" "unprognostic (1.44e-3)" "unprognostic (1.54e-2)" "unprognostic (4.11e-1)" "unprognostic (1.61e-2)" "unprognostic (2.73e-2)" "unprognostic (2.08e-1)" "unprognostic (5.38e-2)" "unprognostic (8.69e-2)" GRHPR "GLXR, PH2" ENSG00000137106 "Glyoxylate and hydroxypyruvate reductase" Q9UBQ7 9 37422666-37436990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 652.5" "Group enriched" "Detected in all" 4 "Hepatocytes: 961.0;Proximal tubular cells: 704.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022971, HPA078575" Enhanced Approved Nucleoplasm,Cytosol NA NA 2700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA022971: AB_1849975, HPA078575: " "prognostic favorable (7.00e-5)" "unprognostic (6.84e-2)" "unprognostic (2.62e-1)" "unprognostic (2.64e-3)" "unprognostic (5.78e-3)" "unprognostic (3.04e-1)" "unprognostic (1.02e-3)" "unprognostic (1.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.49e-2)" "unprognostic (5.88e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.39e-9)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 916.5;kidney: 943.1;liver: 2610.5" "Group enriched" "Detected in many" 5 "Exocrine glandular cells: 1347.6;Granulosa cells: 2988.9;Hepatocytes: 1592.9;Proximal enterocytes: 5185.2;Proximal tubular cells: 2459.8;Sertoli cells: 1442.9;Theca cells: 3000.7" "Cancer enriched" "Detected in many" 4 "liver cancer: 555.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 76.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Leydig cells" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 27800000 "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favorable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Group enriched" "Detected in many" 5 "Cholangiocytes: 204.0;Exocrine glandular cells: 418.2;Hepatocytes: 193.3;Proximal enterocytes: 414.8;Proximal tubular cells: 620.3;Respiratory ciliated cells: 429.0" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "liver cancer: 24.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Sertoli cells" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 479.1;liver: 609.6" "Cell type enhanced" "Detected in many" "granulocytes: 9.3;Melanocytes: 10.4;Thymic epithelial cells: 19.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Region enriched" "Detected in all" 18 "cerebral cortex: 479.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bladder cancer: 94.9" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" Cytosol "Cytokinetic bridge" "CAB022669: , CAB047357: , HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 657.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 817.0;Hofbauer cells: 733.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 19: Macrophages - Innate immune response" "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favorable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 141.7;Thymic epithelial cells: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 140000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 229.3;Proximal enterocytes: 255.1;Proximal tubular cells: 137.9" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.3;liver cancer: 10.0" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 98.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cancer enhanced" "Detected in some" "Leukemia: 6.4;liver cancer: 3.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 29: Hepatocytes - Metabolism" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" HAMP "HEPC, HFE2B, LEAP-1, LEAP1" ENSG00000105697 "Hepcidin antimicrobial peptide" P81172 19 35280716-35285143 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hormone" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2054.8" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 2866.1" "Group enriched" "Detected in many" 12 "glioma: 6.5;liver cancer: 16.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "myeloid DC: 1.5;plasmacytoid DC: 4.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 50.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 1900000 10000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (5.53e-2)" "unprognostic (5.02e-4)" "unprognostic (2.10e-3)" "unprognostic (4.69e-3)" "unprognostic (5.35e-2)" "unprognostic (2.24e-1)" "unprognostic (3.92e-2)" "unprognostic (9.36e-2)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.61e-1)" "unprognostic (1.86e-1)" "unprognostic (3.68e-7)" "unprognostic (4.11e-2)" "unprognostic (3.93e-2)" "unprognostic (4.08e-2)" "unprognostic (7.77e-2)" HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Group enriched" "Detected in many" 4 "Hepatocytes: 630.9;Proximal tubular cells: 426.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 45.4;liver cancer: 42.6" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 63.2;Bipolar cells: 102.0;Excitatory neurons: 76.3;Hepatocytes: 148.9;Horizontal cells: 116.0;Microglial cells: 72.1;Muller glia cells: 62.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.0" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 38: Non-specific - mRNA processing" "Cluster 60: Proximal tubular cells - Absorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 401.5;Hepatocytes: 446.5;Kupffer cells: 286.3;Suprabasal keratinocytes: 346.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 492.2;Enteroendocrine cells: 252.7;Hepatocytes: 1106.7;Intestinal goblet cells: 256.8;Paneth cells: 285.3;Undifferentiated cells: 232.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 40.5;colorectal cancer: 64.4;prostate cancer: 43.7" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 301.0;Proximal tubular cells: 256.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cancer enhanced" "Detected in many" "testis cancer: 107.9" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 69: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 12 "Hepatocytes: 1601.8;Proximal tubular cells: 1497.2" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cancer enhanced" "Detected in many" "liver cancer: 45.8;Rhabdoid: 38.6" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 5 "Hepatocytes: 378.7;Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "liver cancer: 21.4;prostate cancer: 58.4" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 208.2;Smooth muscle cells: 76.9" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.6;prostate cancer: 2.3" "Liver - Hepatocytes" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 18: Non-specific - Mixed function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" HPS5 "AIBP63, BLOC2S2, RU2" ENSG00000110756 "HPS5 biogenesis of lysosomal organelles complex 2 subunit 2" Q9UPZ3 11 18278668-18322198 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 35.7" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 95.1;Schwann cells: 79.0" "Cancer enhanced" "Detected in all" "melanoma: 19.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077851 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "HPA077851: " "unprognostic (2.25e-2)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (9.85e-3)" "unprognostic (5.89e-1)" "unprognostic (1.47e-2)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (2.72e-1)" HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 218.6;Hepatocytes: 238.4;Oligodendrocytes: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 57: Non-specific - Translation" "Cluster 70: Basal prostatic cells - Lipid metabolism" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 29: Hepatocytes - Metabolism" "HPA047496: AB_2680068" "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 38.9;Hepatocytes: 58.3;Hofbauer cells: 48.8;Proximal enterocytes: 45.5;Proximal tubular cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.9;Hepatocytes: 121.0;Proximal tubular cells: 50.4" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Enzymes" "Cluster 60: Proximal tubular cells - Absorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 322.1;Granulosa cells: 251.4;Hepatocytes: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 69: Macrophages - Innate immune response" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" IFITM3 "1-8U, DSPA2b" ENSG00000142089 "Interferon induced transmembrane protein 3" Q01628 11 319676-329475 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 2371.6;Thymic epithelial cells: 3637.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2907.6;non-classical monocyte: 3344.3" "Group enriched" "Detected in all" 6 "granulocytes: 2907.6;monocytes: 3344.3;NK-cells: 926.2" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" HPA004337 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "HPA004337: AB_1851427" "unprognostic (4.17e-2)" "unprognostic (4.19e-1)" "unprognostic (1.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.55e-3)" "unprognostic (6.00e-2)" "unprognostic (3.36e-2)" "unprognostic (6.44e-2)" "unprognostic (8.90e-2)" "unprognostic (9.42e-2)" "unprognostic (7.45e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (5.78e-7)" "unprognostic (7.81e-2)" "unprognostic (3.34e-2)" "unprognostic (8.28e-2)" "unprognostic (1.19e-1)" IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1309.2;Fibroblasts: 392.5;Hepatocytes: 240.9;Leydig cells: 1126.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "Myeloma: 23.2" "Breast - Adipocytes (Breast), Colon - Endothelial cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 52: Endometrial stromal cells - ECM organization" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 911.0" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Gastric cancer: 32.4;liver cancer: 84.6;ovarian cancer: 103.1;pancreatic cancer: 51.0" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 655.8;Endometrial stromal cells: 556.9;Endothelial cells: 564.5;Fibroblasts: 649.8;Hepatocytes: 411.2;Thymic epithelial cells: 417.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.5;NK-cell: 37.0" "Group enriched" "Detected in many" 5 "NK-cells: 37.0;T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" NA NA 227000000 410000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 314 "Plasma cells: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 14 "lymphoma: 58.8;Myeloma: 231.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 34: Plasma cells - Humoral immune response" IGSF9 "IGSF9A, KIAA1355, Nrt1" ENSG00000085552 "Immunoglobulin superfamily member 9" Q9P2J2 1 159927039-159945613 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 32.8;retina: 34.8;skin 1: 23.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 67.2;Distal enterocytes: 53.5;Gastric mucus-secreting cells: 32.2;Rod photoreceptor cells: 174.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 2.9;cerebellum: 5.5" HPA037753 Uncertain "Intracellular and membrane" NA NA 140000 "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 44: Photoreceptor cells - Visual perception" "HPA037753: AB_10672915" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (3.30e-2)" "unprognostic (6.06e-3)" "unprognostic (8.93e-3)" "unprognostic (1.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (2.87e-1)" "unprognostic (8.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" IKBKG "FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9" ENSG00000269335 "Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma" Q9Y6K9 X 154541199-154565046 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Disease variant, Ectodermal dysplasia, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000426, CAB010373" Uncertain Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 48: Non-specific - RNA binding" "Cluster 4: Platelets - Platelet activation" Cytosol "CAB010373: AB_2124846, HPA000426: AB_1851572" "unprognostic (7.53e-2)" "unprognostic (2.76e-3)" "unprognostic (1.09e-1)" "unprognostic (3.37e-3)" "unprognostic (9.77e-2)" "unprognostic (3.68e-1)" "unprognostic (9.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (9.87e-2)" "unprognostic (3.57e-2)" "unprognostic (4.41e-2)" "unprognostic (2.78e-1)" "unprognostic (7.07e-2)" "unprognostic (1.36e-2)" IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 3: Suprabasal keratinocytes - Cornification" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 98.4;Granulosa cells: 101.9;Langerhans cells: 90.3;Leydig cells: 151.7;Pancreatic endocrine cells: 340.1;Syncytiotrophoblasts: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 137.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 19: Macrophages - Innate immune response" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 563.4" "Cell type enriched" "Detected in all" 7 "Langerhans cells: 5156.6" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 272.8;non-classical monocyte: 500.8" "Lineage enriched" "Detected in all" 6 "monocytes: 500.8" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 75: Myeloid cells - Innate immune response" Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1900000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA070307: AB_2686249" "unprognostic (1.67e-1)" "unprognostic (4.46e-2)" "unprognostic (1.29e-1)" "unprognostic (6.42e-3)" "unprognostic (3.87e-2)" "unprognostic (1.91e-1)" "unprognostic (6.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.47e-1)" "unprognostic (4.19e-2)" "unprognostic (2.00e-2)" "unprognostic (4.18e-1)" "unprognostic (7.09e-3)" "unprognostic (2.49e-1)" "unprognostic (2.65e-1)" "unprognostic (1.65e-2)" "unprognostic (1.32e-2)" ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 284.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 299.9;Proximal tubular cells: 455.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria Cytosol "HPA043142: AB_10794653" "unprognostic (2.74e-1)" "unprognostic (8.38e-3)" "unprognostic (7.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-1)" "unprognostic (3.09e-1)" "unprognostic (5.82e-2)" "unprognostic (8.59e-2)" "unprognostic (9.90e-3)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.20e-2)" "unprognostic (2.09e-2)" KDM8 "FLJ13798, JMJD5" ENSG00000155666 "Lysine demethylase 8" Q8N371 16 27203508-27221768 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Aminopeptidase, Chromatin regulator, Dioxygenase, Hydrolase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 80.3" "Group enriched" "Detected in many" 7 "Hepatocytes: 59.3;Proximal enterocytes: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026545 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: Non-specific - Transcription" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm Cytosol "HPA026545: AB_1852015" "unprognostic (1.39e-1)" "unprognostic (1.37e-3)" "unprognostic (2.80e-1)" "unprognostic (2.16e-2)" "unprognostic (3.21e-1)" "unprognostic (1.22e-2)" "unprognostic (2.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.95e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.75e-2)" "unprognostic (5.33e-2)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (3.92e-3)" KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 31.5;liver: 91.7" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 273.5" "Group enriched" "Detected in many" 4 "breast cancer: 1.6;liver cancer: 3.3;renal cancer: 3.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 79 "classical monocyte: 11.0;intermediate monocyte: 32.3;memory B-cell: 36.1;myeloid DC: 11.3;naive B-cell: 42.0;non-classical monocyte: 33.8;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 97 "B-cells: 42.0;dendritic cells: 24.3;monocytes: 33.8" "Group enriched" "Detected in many" 6 "Bone cancer: 28.7;breast cancer: 7.9;Kidney cancer: 10.0;lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Testis - Early spermatids" "Region enriched" "Detected in single" 4 "thalamus: 1.1" "Low region specificity" "Detected in many" "HPA031115, HPA056942" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA031115: AB_10601924, HPA056942: AB_2683281" "unprognostic (4.27e-2)" "unprognostic (3.35e-2)" "unprognostic (3.95e-2)" "unprognostic (7.48e-3)" "unprognostic (8.37e-3)" "unprognostic (2.63e-1)" "unprognostic (9.79e-2)" "unprognostic (3.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.75e-3)" "unprognostic (8.07e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (6.49e-8)" "unprognostic (1.60e-2)" "unprognostic (3.65e-2)" "unprognostic (3.36e-2)" "unprognostic (6.81e-2)" KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 1674.3" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Gastric cancer: 7.0;liver cancer: 9.1" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" KRTAP5-6 KRTAP5.6 ENSG00000205864 "Keratin associated protein 5-6" Q6L8G9 11 1697195-1697755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.0;skin 1: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Low region specificity" "Detected in some" NA NA "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 61: Non-specific - Transcription" "prognostic favorable (6.04e-5)" "unprognostic (3.70e-1)" "unprognostic (2.93e-1)" KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 174.7;Ionocytes: 235.2;Langerhans cells: 296.6;monocytes: 242.4;Syncytiotrophoblasts: 205.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 118.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 99.0;Endothelial cells: 72.8;Fibroblasts: 91.7;Hepatocytes: 138.9;Microglial cells: 125.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 65: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 242.8" "Cell type enriched" "Detected in some" 4 "Plasma cells: 155.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 314.8;MAIT T-cell: 285.2;memory CD4 T-cell: 437.6;memory CD8 T-cell: 412.5;naive CD4 T-cell: 289.4;naive CD8 T-cell: 319.4;plasmacytoid DC: 749.3;T-reg: 689.4" "Group enriched" "Detected in all" 8 "dendritic cells: 749.3;T-cells: 689.4" "Cancer enriched" "Detected in many" 9 "Myeloma: 160.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" CAB015363 Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 2: T-cells - T-cell receptor" "CAB015363: AB_629890" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (5.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-3)" "prognostic unfavorable (5.04e-5)" "unprognostic (2.39e-2)" "unprognostic (4.25e-2)" "unprognostic (1.67e-1)" "prognostic favorable (6.92e-6)" LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244300-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 36: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "HPA008862: AB_2137156" "unprognostic (8.08e-3)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.60e-2)" "unprognostic (7.59e-3)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (3.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.71e-7)" "unprognostic (6.53e-2)" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 157.8;Granulosa cells: 305.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 17: Granulosa cells - Transcription regulation" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312591-68449275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease variant, Osteogenesis imperfecta, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.7" "Cell type enhanced" "Detected in many" "Granulosa cells: 82.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Enhanced NA NA 1500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 17: Granulosa cells - Transcription regulation" "CAB013001: AB_2533267, HPA030505: AB_2673505" "unprognostic (3.67e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.13e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.94e-2)" "unprognostic (9.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.78e-1)" "unprognostic (6.82e-2)" "prognostic favorable (3.55e-10)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.42e-2)" LRRC3 "C21orf102, C21orf30, DKFZP434C128, LRRC3DN" ENSG00000160233 "Leucine rich repeat containing 3" Q9BY71 21 44455510-44462196 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 7.7;Hepatocytes: 24.2;Schwann cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA017975 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "HPA017975: AB_1853307" "unprognostic (1.36e-2)" "unprognostic (5.48e-3)" "unprognostic (1.49e-2)" "unprognostic (2.10e-4)" "unprognostic (1.55e-1)" "unprognostic (1.74e-2)" "unprognostic (7.20e-3)" "unprognostic (2.59e-1)" "unprognostic (4.61e-1)" "unprognostic (7.43e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-5)" "unprognostic (6.44e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-2)" "unprognostic (6.66e-3)" LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 66: Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1532.4;Extravillous trophoblasts: 5485.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" LYRM1 A211C6.1 ENSG00000102897 "LYR motif containing 1" O43325 16 20899868-20925006 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.2;Late spermatids: 488.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 154.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 154.9" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059840 Supported Nucleoplasm,Midbody Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: Non-specific - Transcription" "Cluster 6: Late spermatids - Spermatogenesis" Nucleoplasm Midbody "HPA059840: AB_2684137" "unprognostic (4.44e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-2)" "prognostic favorable (7.48e-7)" "unprognostic (3.04e-1)" "unprognostic (1.10e-1)" "unprognostic (3.47e-1)" "unprognostic (8.60e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (3.39e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (1.57e-1)" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "prognostic favorable (9.50e-4)" MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 27.2;Cardiomyocytes: 29.4;Cholangiocytes: 26.9;Endometrial stromal cells: 30.1;Fibroblasts: 17.1;Hepatocytes: 58.1" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.0;Rhabdoid: 14.0" "Breast - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 48: Non-specific - RNA binding" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" METTL7A DKFZP586A0522 ENSG00000185432 "Methyltransferase like 7A" Q9H8H3 12 50923472-50932510 "Metabolic proteins, Predicted membrane proteins" "Host-virus interaction" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 440.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 812.4;Kupffer cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 95.7;classical monocyte: 35.7;eosinophil: 70.7;intermediate monocyte: 38.0;memory B-cell: 32.4;myeloid DC: 31.0;naive B-cell: 34.4;non-classical monocyte: 59.5;plasmacytoid DC: 25.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 83.8" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017434 Supported "Lipid droplets" NA NA 18000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Lipid droplets" "HPA017434: AB_1853835" "unprognostic (2.31e-2)" "unprognostic (2.82e-2)" "unprognostic (9.85e-3)" "unprognostic (9.43e-2)" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.09e-3)" "unprognostic (2.68e-3)" "unprognostic (5.48e-2)" "unprognostic (9.94e-2)" "unprognostic (2.57e-2)" "unprognostic (4.49e-2)" "prognostic favorable (0.00e+0)" "unprognostic (8.64e-2)" "unprognostic (5.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-2)" METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681678-55684611 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 133.1;heart muscle: 124.2;liver: 284.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 30.1;Distal enterocytes: 36.3;Hepatocytes: 74.6;Hofbauer cells: 65.8;Proximal enterocytes: 200.3;Proximal tubular cells: 32.6" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 45 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 59: Proximal enterocytes - Transmembrane transport" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467190-129770983 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 567.8;Proximal tubular cells: 334.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 17: RS4;11 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: AB_2674171, HPA032136: AB_2674172, HPA069497: AB_2732134" "unprognostic (1.10e-1)" "prognostic favorable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1600.2;Basal respiratory cells: 1213.4;Hepatocytes: 4707.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 5: Bronchus - Unknown function" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" MMUT "MCM, MUT" ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463253 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 199.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 87.2;Hepatocytes: 106.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol NA NA 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 15: Non-specific - Protein binding" "Cluster 29: Hepatocytes - Metabolism" Cytosol Mitochondria "HPA035971: AB_10696648, HPA035972: AB_2674895" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.72e-2)" "unprognostic (3.18e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (1.89e-2)" "unprognostic (6.57e-2)" "unprognostic (9.89e-2)" "prognostic favorable (8.71e-13)" "unprognostic (5.38e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-3)" "unprognostic (1.91e-1)" MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.3;liver: 16.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.7;Hepatocytes: 34.2;Proximal enterocytes: 23.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 14: Endometrium - Transcription regulation" Mitochondria Cytosol "HPA039412: AB_2676496, HPA047958: AB_2680225" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavorable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 549.0;Hepatocytes: 617.4;Paneth cells: 523.7;Proximal enterocytes: 1336.8;Proximal tubular cells: 464.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 50: Enterocytes - Absorption" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 418.6;Hepatocytes: 471.9;Kupffer cells: 264.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 198.3;Proximal enterocytes: 54.8;Proximal tubular cells: 42.9;Thymic epithelial cells: 45.4" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 263.7;Alveolar cells type 2: 142.7;Hepatocytes: 375.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 72: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 15.9;liver: 48.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 17.7;Proximal enterocytes: 45.5;Proximal tubular cells: 17.0;Spermatocytes: 13.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA027300: AB_2672207" "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391282-18401218 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "intestine: 33.5;liver: 128.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 16.7;Hepatocytes: 63.2;Intestinal goblet cells: 10.3;Paneth cells: 15.3;Proximal enterocytes: 35.5" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.9" "Colon - Colon enterocytes" HPA043704 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA043704: AB_2678625" "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" NBPF9 AE01 ENSG00000269713 "NBPF member 9" P0DPF3 1 149054027-149103561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 22.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 49.5" "Group enriched" "Detected in all" 4 "granulocytes: 49.5;monocytes: 14.2" "Low cancer specificity" "Detected in all" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (1.25e-2)" "unprognostic (1.02e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-1)" "unprognostic (3.33e-3)" "unprognostic (1.94e-1)" "unprognostic (2.15e-2)" "unprognostic (2.93e-1)" "unprognostic (2.10e-1)" "unprognostic (6.90e-2)" "unprognostic (9.42e-6)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (6.63e-3)" "unprognostic (8.80e-2)" NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 71.7;Hepatocytes: 119.6;Intestinal goblet cells: 37.5;Oligodendrocyte precursor cells: 48.1;Paneth cells: 49.5;Proximal enterocytes: 69.7" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.4;liver cancer: 8.7" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 117.6;Proximal tubular cells: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 16: Non-specific - RNA binding" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" NIPSNAP3A "DKFZp564D177, FLJ13953, HSPC299, MGC14553" ENSG00000136783 "Nipsnap homolog 3A" Q9UFN0 9 104747683-104760120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042491 Approved NA NA 13000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" "HPA042491: AB_2678023" "unprognostic (1.03e-1)" "unprognostic (9.13e-2)" "unprognostic (7.40e-2)" "unprognostic (3.52e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.64e-1)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (2.32e-1)" "unprognostic (2.59e-1)" "unprognostic (1.49e-2)" "unprognostic (1.91e-3)" "unprognostic (2.92e-1)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 388.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 566.0;Hepatocytes: 4210.0;Skeletal myocytes: 1464.8;Thymic epithelial cells: 867.0" "Cancer enhanced" "Detected in all" "renal cancer: 204.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 48.2" "Skin - Macrophages, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 410000 "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" Cytosol "HPA059180: AB_2683940" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-6)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;liver: 120.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 90.5;Hepatocytes: 110.4;Proximal enterocytes: 341.9;Proximal tubular cells: 151.1" "Group enriched" "Detected in some" 11 "liver cancer: 18.7;renal cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 4.9;Kidney cancer: 14.0;liver cancer: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA047699 Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" Nucleoplasm "HPA047699: AB_10965320" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.77e-3)" NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 16: Non-specific - RNA binding" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" NUDT7 ENSG00000140876 "Nudix hydrolase 7" P0C024 16 77722492-77742260 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.8;Hepatocytes: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042042 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Golgi apparatus" Nucleoplasm "HPA042042: AB_10806232" "unprognostic (1.92e-1)" "unprognostic (1.17e-2)" "unprognostic (6.64e-2)" "unprognostic (5.95e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.46e-2)" "unprognostic (4.74e-2)" "unprognostic (4.52e-1)" "prognostic favorable (5.36e-11)" "unprognostic (1.19e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-2)" OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 108.3;Hepatocytes: 197.7;Muller glia cells: 269.0;Theca cells: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: Non-specific - Transcription" "Cluster 53: Connective tissue cells - ECM organization" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 209.2;Late spermatids: 380.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 7: NK-cells - Immune response regulation" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" OSGIN1 "BDGI, OKL38" ENSG00000140961 "Oxidative stress induced growth inhibitor 1" Q9UJX0 16 83931311-83966332 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 147.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 76.7;Late spermatids: 339.8;Proximal enterocytes: 97.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 65.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 12.6" "Group enriched" "Detected in many" 8 "granulocytes: 4.2;monocytes: 12.6" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 131.0" "Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019239 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 16: Non-specific - RNA binding" "Nucleoplasm, Cytosol" "HPA019239: AB_1854779" "unprognostic (8.36e-2)" "unprognostic (9.44e-2)" "unprognostic (4.28e-2)" "prognostic favorable (4.89e-5)" "unprognostic (3.31e-3)" "unprognostic (9.14e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.20e-2)" "unprognostic (2.80e-2)" "unprognostic (2.45e-2)" "unprognostic (2.48e-2)" "unprognostic (8.28e-3)" "unprognostic (1.89e-1)" OTC OTCase ENSG00000036473 "Ornithine carbamoyltransferase" P00480 X 38352586-38421446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 124 "intestine: 112.4;liver: 377.8" "Group enriched" "Detected in some" 4 "Hepatocytes: 132.6;Proximal enterocytes: 86.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 59.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Smooth muscle cells, Liver - Hepatocytes, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000243, HPA000570" Enhanced Supported Mitochondria NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA000243: AB_1079535, HPA000570: AB_1079534" "unprognostic (6.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.89e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.70e-3)" "unprognostic (5.61e-2)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762481-42764261 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 56.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 6.5;Melanocytes: 5.2;Paneth cells: 5.3;Proximal enterocytes: 14.1" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 67.0;eosinophil: 144.5" "Lineage enriched" "Detected in many" 79 "granulocytes: 144.5" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" HPA051433 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836889-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 496.6;liver: 1408.4" "Group enriched" "Detected in some" 5 "Cholangiocytes: 246.4;Hepatocytes: 751.1;Proximal tubular cells: 217.7" "Cancer enriched" "Detected in some" 17 "liver cancer: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 48.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" No NA 40000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum, Vesicles" "HPA028407: AB_10601241, HPA031642: AB_2673974" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (4.47e-2)" "unprognostic (9.13e-3)" "unprognostic (5.19e-2)" "unprognostic (5.99e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.27e-1)" "unprognostic (6.60e-2)" "unprognostic (4.45e-3)" "unprognostic (1.94e-3)" "unprognostic (1.83e-1)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (1.64e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-2)" PANK1 "MGC24596, PANK, PANK1a, PANK1b" ENSG00000152782 "Pantothenate kinase 1" Q8TE04 10 89579497-89645572 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 45.2;liver: 109.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 41.5;Hepatocytes: 143.6;Proximal tubular cells: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (6.71e-2)" "unprognostic (6.97e-2)" "prognostic favorable (1.50e-4)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.55e-4)" "unprognostic (4.61e-2)" "prognostic favorable (1.55e-10)" "unprognostic (3.49e-2)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" "unprognostic (6.64e-2)" PARP16 "ARTD15, C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Metabolic proteins, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 32.6;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 44: Photoreceptor cells - Visual perception" "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039447-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 48.7" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 29.9;Hepatocytes: 28.5;Kupffer cells: 20.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;medulla oblongata: 2.1;pons: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 143000000 420000000 "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 29: Hepatocytes - Metabolism" "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.40e-4)" PCTP STARD2 ENSG00000141179 "Phosphatidylcholine transfer protein" Q9UKL6 17 55751051-55842830 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.0" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 71.9;Hepatocytes: 75.5;Syncytiotrophoblasts: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 241.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA022979 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 70: Basal prostatic cells - Lipid metabolism" "Nucleoplasm, Nucleoli" "HPA022979: AB_2671018" "unprognostic (1.14e-1)" "unprognostic (5.20e-2)" "unprognostic (4.27e-2)" "unprognostic (7.35e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.43e-6)" "unprognostic (9.35e-3)" "unprognostic (2.69e-1)" "unprognostic (2.07e-1)" "unprognostic (8.65e-2)" "unprognostic (6.63e-3)" "unprognostic (1.16e-1)" "unprognostic (5.36e-3)" "unprognostic (1.26e-1)" "unprognostic (4.93e-1)" "unprognostic (6.89e-3)" "unprognostic (3.04e-1)" PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 54: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 92.9;Proximal enterocytes: 52.2;Proximal tubular cells: 78.6" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 166.2;liver: 267.4" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 129.4;Hepatocytes: 215.6;Pancreatic endocrine cells: 173.5;Peritubular cells: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 49: Non-specific - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 37.4;Late spermatids: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 50: Enterocytes - Absorption" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" PEX13 ENSG00000162928 "Peroxisomal biogenesis factor 13" Q92968 2 61017225-61051990 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032141, HPA032142, CAB032689" Enhanced Supported Peroxisomes NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 5: Bronchus - Unknown function" Peroxisomes "CAB032689: AB_2162137, HPA032141: AB_2674176, HPA032142: AB_10669676" "unprognostic (2.44e-3)" "unprognostic (4.10e-2)" "unprognostic (7.84e-3)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (5.08e-2)" "unprognostic (2.05e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (5.42e-2)" "unprognostic (4.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (2.63e-2)" PEX14 ENSG00000142655 "Peroxisomal biogenesis factor 14" O75381 1 10472288-10630758 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 63.8;Syncytiotrophoblasts: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046104, HPA049231" Supported Supported "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 38: Non-specific - mRNA processing" "Cluster 44: Photoreceptor cells - Visual perception" Peroxisomes "Nucleoli fibrillar center" "HPA046104: AB_2679539, HPA049231: AB_2680683" "unprognostic (7.23e-3)" "unprognostic (7.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-2)" "unprognostic (3.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.32e-2)" "unprognostic (2.32e-1)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (3.05e-3)" "unprognostic (9.67e-3)" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (3.75e-2)" PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 479.3;Theca cells: 641.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Approved "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 48: Non-specific - RNA binding" "Cluster 29: Hepatocytes - Metabolism" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 42.8;Hepatocytes: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 48: Non-specific - RNA binding" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 130.8;Inhibitory neurons: 138.3;Langerhans cells: 264.8;Microglial cells: 175.1;Oligodendrocyte precursor cells: 520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" PIPOX LPIPOX ENSG00000179761 "Pipecolic acid and sarcosine oxidase" Q9P0Z9 17 28950513-29057216 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "kidney: 146.0;liver: 506.6" "Group enriched" "Detected in some" 8 "Hepatocytes: 226.9;Proximal tubular cells: 144.1" "Cancer enriched" "Detected in many" 5 "liver cancer: 73.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 11.3;Sarcoma: 12.8" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 380000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "unprognostic (8.02e-2)" "unprognostic (3.50e-4)" "unprognostic (3.03e-1)" "unprognostic (6.25e-3)" "unprognostic (1.52e-1)" "unprognostic (5.01e-2)" "unprognostic (1.95e-3)" "unprognostic (1.15e-2)" "unprognostic (2.17e-1)" "unprognostic (3.45e-1)" "prognostic favorable (1.49e-4)" "unprognostic (2.39e-1)" "unprognostic (3.13e-3)" "unprognostic (2.58e-3)" "unprognostic (2.01e-1)" "unprognostic (2.79e-2)" "unprognostic (1.22e-1)" PITPNB VIB1B ENSG00000180957 "Phosphatidylinositol transfer protein beta" P48739 22 27851669-27920134 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 300000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (9.29e-2)" "unprognostic (1.64e-1)" "unprognostic (4.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.34e-1)" "unprognostic (7.52e-3)" "unprognostic (4.78e-2)" "unprognostic (8.22e-3)" "unprognostic (1.56e-3)" "unprognostic (2.42e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (6.28e-2)" "unprognostic (2.89e-2)" "unprognostic (1.64e-1)" PKD1L3 ENSG00000277481 "Polycystin 1 like 3, transient receptor potential channel interacting" Q7Z443 16 71929538-71999978 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.5;Inhibitory neurons: 2.1;Microglial cells: 1.8;Oligodendrocytes: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-2)" "unprognostic (7.24e-2)" "unprognostic (1.68e-1)" "unprognostic (1.74e-1)" "unprognostic (9.90e-4)" "unprognostic (2.22e-1)" "unprognostic (1.35e-6)" "unprognostic (6.71e-2)" "unprognostic (1.73e-1)" "unprognostic (1.25e-1)" "unprognostic (1.93e-3)" PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Group enriched" "Detected in some" 8 "Erythroid cells: 61.6;Hepatocytes: 51.0;Late spermatids: 24.9;Proximal enterocytes: 34.7;Proximal tubular cells: 37.2" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 7.1;skin cancer: 2.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 1638.0" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823, HPA053770" Supported Approved Vesicles "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" Vesicles "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532, HPA053770: AB_2682256" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 185.3;Alveolar cells type 1: 320.2;Suprabasal keratinocytes: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Cytosol" "HPA000895: , HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 33.8;Hepatocytes: 36.1;Rod photoreceptor cells: 35.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 29: Hepatocytes - Metabolism" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 421.3;Ionocytes: 320.1;Proximal enterocytes: 282.0;Theca cells: 454.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 5: Bronchus - Unknown function" Vesicles "Nucleoplasm, Cytosol" "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 290.2;Late spermatids: 182.3;Spermatocytes: 117.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Cell type enriched" "Detected in some" 11 "Thymic epithelial cells: 3678.6" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 31.9" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 264.5;Thymic epithelial cells: 87.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 29: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" PROSER2 "C10orf47, MGC35403" ENSG00000148426 "Proline and serine rich 2" Q86WR7 10 11823339-11872277 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.7;Cholangiocytes: 21.2;Glandular and luminal cells: 28.2;Hepatocytes: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 14.4" HPA041337 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA 220000 "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cytosol" "HPA041337: AB_10794663" "unprognostic (2.36e-3)" "unprognostic (1.39e-1)" "unprognostic (3.55e-2)" "unprognostic (1.19e-1)" "unprognostic (4.60e-2)" "unprognostic (7.60e-3)" "unprognostic (4.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (1.25e-3)" "unprognostic (1.61e-1)" "unprognostic (1.26e-2)" "unprognostic (4.04e-2)" "unprognostic (3.01e-1)" "unprognostic (5.06e-2)" "unprognostic (8.69e-2)" PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 109.2" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 64.6" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" NA NA 1720000000 650000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 29: Hepatocytes - Metabolism" "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favorable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 565.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.6" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 300000 "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 15: Smooth muscle cells - Muscle contraction" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: AB_10673042" "unprognostic (3.11e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (4.16e-1)" "unprognostic (1.01e-1)" "unprognostic (8.69e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (3.21e-1)" "unprognostic (2.35e-3)" "unprognostic (1.55e-2)" PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 225.8;Hepatocytes: 630.6;Proximal enterocytes: 357.8;Proximal tubular cells: 258.3" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 7: Neuronal cell lines - Stereocilium" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 162.8;Hofbauer cells: 166.2;Muller glia cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" RAB33B DKFZP434G099 ENSG00000172007 "RAB33B, member RAS oncogene family" Q9H082 4 139453232-139476609 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 22.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048367 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 36: Spermatids - Spermatogenesis" "HPA048367: AB_2680372" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-1)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-2)" "unprognostic (9.45e-2)" "unprognostic (2.36e-2)" "unprognostic (4.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.59e-1)" "unprognostic (8.06e-3)" "prognostic favorable (9.19e-4)" RAB43 "ISY1, RAB11B, RAB41" ENSG00000172780 "RAB43, member RAS oncogene family" Q86YS6 3 129087569-129122801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.0;Gastric mucus-secreting cells: 6.0;Plasma cells: 8.0;Squamous epithelial cells: 2.4;Thymic epithelial cells: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.2" "Group enriched" "Detected in many" 5 "granulocytes: 11.2;T-cells: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046840, HPA060085" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 61: Non-specific - Transcription" "Plasma membrane" "HPA046840: , HPA060085: AB_2684199" "unprognostic (3.01e-1)" "unprognostic (1.14e-2)" "unprognostic (3.08e-1)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.36e-2)" "unprognostic (3.17e-2)" "unprognostic (4.16e-1)" "unprognostic (8.68e-2)" "unprognostic (3.14e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.82e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.9;Microglial cells: 90.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 75: Myeloid cells - Innate immune response" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" RBFA "C18orf22, FLJ21172, HsT169" ENSG00000101546 "Ribosome binding factor A" Q8N0V3 18 80034389-80050651 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040485, HPA041479" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 16: Non-specific - RNA binding" Mitochondria "HPA040485: AB_10795368, HPA041479: AB_10795697" "unprognostic (5.31e-3)" "unprognostic (3.21e-2)" "unprognostic (1.87e-1)" "unprognostic (4.55e-2)" "unprognostic (7.33e-2)" "unprognostic (5.00e-3)" "prognostic unfavorable (2.06e-6)" "unprognostic (2.98e-1)" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (4.28e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (3.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.82e-1)" "unprognostic (5.00e-3)" RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792944-4885917 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.8" "Cell type enhanced" "Detected in all" "Early spermatids: 71.9;Hepatocytes: 199.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA071308: AB_2686384" "prognostic favorable (5.48e-4)" "unprognostic (7.60e-3)" "unprognostic (7.55e-2)" "unprognostic (4.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.29e-1)" "prognostic favorable (8.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.59e-2)" "prognostic favorable (2.40e-7)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (3.66e-2)" RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Approved Nucleoplasm No No 1100000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 16: Non-specific - RNA binding" Nucleoplasm "HPA011564: AB_1079803, HPA031673: AB_2673989" "unprognostic (4.17e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-3)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "prognostic favorable (4.81e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (4.14e-2)" RFPL4A "RFPL4, RNF210" ENSG00000223638 "Ret finger protein like 4A" A6NLU0 19 55759014-55763175 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.4;liver: 3.4;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.0;Langerhans cells: 1.0;Schwann cells: 1.2" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7" "Group enriched" "Detected in many" 4 "dendritic cells: 3.1;monocytes: 9.7" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.6;Bone cancer: 5.7;Brain cancer: 2.8;Sarcoma: 1.5" "Liver - Hepatocytes" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "Centrosome, Cytosol" "HPA046368: AB_2679640" "unprognostic (3.74e-1)" "unprognostic (2.96e-2)" "unprognostic (9.20e-2)" RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 184.7;liver: 383.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 56.0;Granulosa cells: 64.4;Hepatocytes: 205.2;Muller glia cells: 51.0;Peritubular cells: 71.4;Proximal tubular cells: 183.4" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 11.4" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 280000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA029102: AB_10599846, HPA029103: AB_10602097, HPA029104: " "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favorable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favorable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Group enriched" "Detected in all" 6 "Hepatocytes: 942.8;Proximal tubular cells: 1081.8" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 60: Proximal tubular cells - Absorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 37.9;Enteroendocrine cells: 57.0;Gastric mucus-secreting cells: 49.5;Hepatocytes: 48.2;Intestinal goblet cells: 91.8;Proximal enterocytes: 39.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 44.9;Extravillous trophoblasts: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" RPRD1B "C20orf77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, K-H, Kub5-Hera, NET60" ENSG00000101413 "Regulation of nuclear pre-mRNA domain containing 1B" Q9NQG5 20 38033725-38127780 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 72.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066290, HPA070590, HPA072645" Enhanced Supported Nucleoplasm NA NA 28000 "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 29: Hepatocytes - Metabolism" Nucleoplasm "HPA066290: AB_2685650, HPA070590: , HPA072645: " "unprognostic (3.14e-2)" "unprognostic (3.30e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-3)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (2.68e-2)" "unprognostic (4.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.20e-2)" "unprognostic (1.14e-1)" "unprognostic (5.25e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (5.77e-2)" "unprognostic (1.36e-2)" "unprognostic (3.47e-1)" SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 47.9;liver: 114.4;pancreas: 43.2" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 109.4" "Cancer enriched" "Detected in many" 8 "liver cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.3;naive CD4 T-cell: 6.7;T-reg: 8.8" "Lineage enriched" "Detected in single" 16 "T-cells: 8.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA057267, HPA058086" Approved Approved Mitochondria NA NA 230000 "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" Mitochondria "HPA057267: AB_2683388, HPA058086: AB_2683601" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.62e-4)" "unprognostic (5.83e-2)" "unprognostic (1.42e-3)" "unprognostic (2.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (7.74e-3)" "unprognostic (2.78e-1)" "unprognostic (3.48e-1)" "unprognostic (9.73e-2)" "unprognostic (1.30e-2)" SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 300.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 29: Hepatocytes - Metabolism" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 185.2;Hepatocytes: 230.5;Langerhans cells: 159.2;Smooth muscle cells: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416, HPA074427" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB025123: , HPA044416: AB_2678934, HPA074427: " "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50200979-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 90.7;Late spermatids: 169.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" "Intracellular and membrane" Yes NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: Non-specific - Unknown function" "Cluster 51: Late spermatids - Spermatogenesis" Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.79e-1)" "unprognostic (2.07e-3)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-1)" "unprognostic (5.62e-2)" "unprognostic (8.20e-3)" "unprognostic (8.91e-2)" "unprognostic (1.81e-2)" "unprognostic (7.31e-2)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "prognostic favorable (8.32e-4)" SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 3174.3;Proximal enterocytes: 5487.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 197.2" "Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 59: Proximal enterocytes - Transmembrane transport" Vesicles "HPA070409: AB_2686265" "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 19.7;Exocrine glandular cells: 26.8;Fibroblasts: 14.9;Hepatocytes: 11.5;Mucus glandular cells: 37.1;Pancreatic endocrine cells: 10.3;Schwann cells: 10.4;Serous glandular cells: 11.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 439.9" "Breast - Breast glandular cells, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 61: Non-specific - Transcription" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" SERPINA4 "KAL, kallistatin, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 550.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 227.1;Exocrine glandular cells: 85.3;Hepatocytes: 402.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.2;Gastric cancer: 2.1;liver cancer: 5.2" "Liver - Hepatocytes, Stomach - Parietal cells" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" NA NA 14500000000 14000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 241.9;Cholangiocytes: 363.8;Endometrial ciliated cells: 146.2;Glandular and luminal cells: 335.7;Hepatocytes: 176.9;Late spermatids: 275.7;Peritubular cells: 142.4;Sertoli cells: 362.1" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 25.5;liver cancer: 63.9" "Liver - Hepatocytes, Pancreas - Macrophages, Skin - Fibroblast_2, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Group enriched" "Detected in many" 5 "Hepatocytes: 824.3;Kupffer cells: 257.5" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Group enriched" "Detected in many" 12 "Gastric cancer: 50.5;liver cancer: 36.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, HPA005943, CAB024863" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "Golgi apparatus" "CAB024863: , HPA001885: AB_1079922, HPA005943: " "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 667.9;Ductal cells: 640.1;Fibroblasts: 830.3;Hepatocytes: 2202.4;Leydig cells: 755.1;Thymic epithelial cells: 1994.0" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Cancer enhanced" "Detected in many" "liver cancer: 32.4;testis cancer: 41.8" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 57: Non-specific - Translation" "Cluster 1: T-cells - Immune response" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 50.7;Late spermatids: 125.9;Proximal enterocytes: 29.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 6: Late spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.9;Alveolar cells type 2: 9.4;Cholangiocytes: 15.4;Collecting duct cells: 7.9;Gastric mucus-secreting cells: 10.1;Glandular and luminal cells: 8.4;Hepatocytes: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 2: DU4475 - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" SHMT2 SHMT ENSG00000182199 "Serine hydroxymethyltransferase 2" P34897 12 57229573-57234935 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Cardiomyopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020543, HPA020549" Enhanced Supported Microtubules,Mitochondria NA NA 390000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" Mitochondria Microtubules "HPA020543: AB_1856833, HPA020549: AB_1856834" "prognostic unfavorable (8.37e-5)" "unprognostic (1.24e-1)" "unprognostic (1.90e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (4.97e-2)" "unprognostic (1.58e-2)" "unprognostic (9.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (4.84e-8)" "unprognostic (3.05e-1)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (4.74e-2)" SHPK "CARKL, SHK" ENSG00000197417 Sedoheptulokinase Q9UHJ6 17 3608240-3636250 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 20.5;Rod photoreceptor cells: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA024361, HPA064939" Enhanced Approved "Nucleoplasm,Nuclear speckles" NA NA 350000 "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 49: Non-specific - Unknown function" "Cluster 44: Photoreceptor cells - Visual perception" "Nucleoplasm, Nuclear speckles" "HPA024361: AB_1846030, HPA064939: AB_2685388" "unprognostic (1.75e-2)" "unprognostic (1.51e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (3.57e-3)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-2)" "unprognostic (1.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.08e-2)" "unprognostic (1.42e-1)" "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741125-150763477 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 183.4;Syncytiotrophoblasts: 347.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 43: Non-specific - Mitochondria" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: AB_2684470" "prognostic favorable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 187.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 101.5;Hepatocytes: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 55: Non-specific - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" "CAB013470: AB_2533521, HPA018002: AB_1854802, HPA024071: AB_1854803" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (8.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.89e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.42e-4)" SLC16A13 MCT13 ENSG00000174327 "Solute carrier family 16 member 13" Q7RTY0 17 7036015-7040117 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 5.8;Collecting duct cells: 5.9;Hepatocytes: 6.5;Squamous epithelial cells: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065245 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 49: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Golgi apparatus" Cytosol "HPA065245: AB_2685443" "unprognostic (5.61e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (1.78e-1)" "unprognostic (2.22e-3)" "unprognostic (9.53e-2)" "unprognostic (1.62e-1)" "unprognostic (8.72e-2)" "unprognostic (1.81e-1)" "unprognostic (2.60e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.44e-2)" "unprognostic (7.31e-3)" "unprognostic (9.70e-3)" "unprognostic (3.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.14e-1)" SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Hepatocytes: 53.2;Inhibitory neurons: 21.1;Oligodendrocyte precursor cells: 22.1;Peritubular cells: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 23.8;Hepatocytes: 32.7;Hofbauer cells: 16.4;Plasma cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 30.1" "Breast - Plasma cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047470 Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" SLC22A7 "NLT, OAT2" ENSG00000137204 "Solute carrier family 22 member 7" Q9Y694 6 43295694-43305538 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 427.9" "Group enriched" "Detected in some" 8 "Hepatocytes: 188.5;Proximal tubular cells: 53.1" "Cancer enriched" "Detected in some" 37 "liver cancer: 81.5" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 1.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA030220 Approved NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "HPA030220: AB_10603027" "unprognostic (9.17e-2)" "unprognostic (9.73e-4)" "unprognostic (2.13e-1)" "prognostic favorable (5.48e-6)" "unprognostic (1.45e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 183.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.4;Late spermatids: 77.5;Proximal enterocytes: 54.1;Proximal tubular cells: 68.1;Undifferentiated cells: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 16: Non-specific - RNA binding" Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" SLC25A13 "ARALAR2, CITRIN, CTLN2" ENSG00000004864 "Solute carrier family 25 member 13" Q9UJS0 7 96120220-96322147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 150.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 154.6;Oligodendrocytes: 415.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018997 Enhanced Supported Mitochondria NA NA 21000 "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA018997: AB_1857023" "unprognostic (3.61e-2)" "unprognostic (7.99e-2)" "unprognostic (6.99e-2)" "unprognostic (7.19e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (1.42e-2)" "unprognostic (6.67e-2)" "unprognostic (2.31e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-1)" "unprognostic (6.99e-2)" "prognostic favorable (9.14e-4)" "unprognostic (1.15e-1)" "unprognostic (1.05e-1)" "unprognostic (3.32e-1)" "unprognostic (7.09e-2)" SLC29A3 "ENT3, FLJ11160" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319259-71381423 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.7;Extravillous trophoblasts: 49.8;Hofbauer cells: 30.2;Syncytiotrophoblasts: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046085, HPA054976, HPA057905" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 28: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA046085: AB_2679531, HPA054976: AB_2682659, HPA057905: AB_2683550" "unprognostic (1.73e-1)" "unprognostic (2.38e-3)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (1.28e-1)" "unprognostic (4.71e-1)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (3.37e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.43e-3)" SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 412.5" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bladder cancer: 4.5;Kidney cancer: 7.0;liver cancer: 4.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997, HPA069490" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860, HPA069490: " "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" SLC2A4RG "GEF, HDBP1, Si-1-2, Si-1-2-19" ENSG00000125520 "SLC2A4 regulator" Q9NR83 20 63739776-63744050 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 150.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 123.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA063050 Approved "Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 16: Non-specific - RNA binding" "Nuclear speckles" "HPA063050: AB_2684930" "unprognostic (2.89e-2)" "unprognostic (2.32e-1)" "unprognostic (1.84e-2)" "unprognostic (5.78e-2)" "unprognostic (2.07e-3)" "unprognostic (6.48e-3)" "unprognostic (2.70e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-3)" "unprognostic (3.22e-1)" SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 84.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" SLC37A4 "G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d" ENSG00000137700 "Solute carrier family 37 member 4" 11 119024114-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 177.1;Hepatocytes: 154.0;Proximal enterocytes: 267.6;Proximal tubular cells: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 846.8;Suprabasal keratinocytes: 712.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 259.3;Hepatocytes: 493.6;Kupffer cells: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 29: Hepatocytes - Metabolism" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" SLC41A2 DKFZP434K0427 ENSG00000136052 "Solute carrier family 41 member 2" Q96JW4 12 104802553-104958744 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 114.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 99.0;Inhibitory neurons: 91.6;Oligodendrocyte precursor cells: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "myeloid DC: 4.1;plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 15 "dendritic cells: 12.2" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038658 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 38: Neurons - Neuronal signaling" "HPA038658: AB_10671747" "unprognostic (7.19e-2)" "unprognostic (4.38e-3)" "unprognostic (1.94e-2)" "unprognostic (2.38e-1)" "unprognostic (6.06e-3)" "unprognostic (3.05e-2)" "prognostic favorable (9.94e-4)" "unprognostic (1.35e-1)" "unprognostic (3.68e-1)" "unprognostic (3.65e-1)" "unprognostic (4.20e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-2)" "unprognostic (5.30e-2)" SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 68.3;granulocytes: 64.2;Hofbauer cells: 74.1;Langerhans cells: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cancer enhanced" "Detected in all" "skin cancer: 216.0" "Colon - Endothelial cells" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 65: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 155.3;Late spermatids: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" SMIM14 "C4orf34, FLJ13289" ENSG00000163683 "Small integral membrane protein 14" Q96QK8 4 39546336-39638902 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 559.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051299 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 26: Intestinal epithelial cells - Absorption" "HPA051299: AB_2681429" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.48e-2)" "prognostic favorable (3.00e-6)" "prognostic favorable (3.47e-4)" "unprognostic (2.67e-2)" "unprognostic (1.54e-1)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (7.18e-2)" "prognostic favorable (2.07e-4)" "unprognostic (6.66e-2)" "unprognostic (1.33e-1)" "unprognostic (9.50e-2)" "unprognostic (4.92e-3)" SMLR1 ENSG00000256162 "Small leucine rich protein 1" H3BR10 6 130827406-130837135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 56.6" "Group enriched" "Detected in some" 16 "Hepatocytes: 321.2;Proximal enterocytes: 146.2" "Cancer enriched" "Detected in some" 20 "liver cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "liver cancer: 7.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA066060 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA066060: AB_2685607" "unprognostic (1.73e-1)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.32e-2)" "unprognostic (2.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (6.43e-3)" "unprognostic (2.68e-3)" "unprognostic (3.29e-1)" SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Group enriched" "Detected in many" 4 "Hepatocytes: 271.3;Prostatic glandular cells: 163.8;Proximal tubular cells: 149.5" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 50: L-1236 & L-428 - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" SPDYC Ringo2 ENSG00000204710 "Speedy/RINGO cell cycle regulator family member C" Q5MJ68 11 65170154-65173244 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "liver: 3.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 2.5;Extravillous trophoblasts: 4.6;Hepatocytes: 2.0;Late spermatids: 8.9;Spermatogonia: 3.5;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "breast cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9" "Liver - Hepatocytes" "Not detected" "Not detected" HPA039891 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 4: Platelets - Platelet activation" "HPA039891: AB_10795260" "prognostic unfavorable (1.20e-5)" "unprognostic (7.35e-2)" "unprognostic (4.42e-2)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (1.93e-2)" "unprognostic (1.31e-3)" "unprognostic (5.08e-2)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-1)" "unprognostic (4.75e-2)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" "unprognostic (6.60e-4)" SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 167.0;Proximal tubular cells: 95.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" SPTSSA "C14orf147, ssSPTa" ENSG00000165389 "Serine palmitoyltransferase small subunit A" Q969W0 14 34432788-34462240 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 463.3;Syncytiotrophoblasts: 569.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (4.00e-1)" "unprognostic (3.19e-2)" "unprognostic (2.44e-2)" "unprognostic (6.64e-2)" "unprognostic (1.19e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (5.86e-2)" SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Lipid metabolism, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 9 "Club cells: 21.0;Early spermatids: 54.4;Endometrial ciliated cells: 26.6;Hepatocytes: 21.2;Late spermatids: 71.9;Respiratory ciliated cells: 18.7" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 36: Spermatids - Spermatogenesis" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" ST20-MTHFS ENSG00000259332 "ST20-MTHFS readthrough" 15 79845150-79923754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.6" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Basal squamous epithelial cells: 2.2;Collecting duct cells: 2.0;Erythroid cells: 3.4;Gastric mucus-secreting cells: 5.4;Pancreatic endocrine cells: 3.4;Schwann cells: 4.0;Squamous epithelial cells: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 492.2" "Group enriched" "Detected in all" 4 "granulocytes: 492.2;monocytes: 133.6" "Low cancer specificity" "Detected in all" HPA008067 Uncertain NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "HPA008067: AB_1078882" "unprognostic (9.84e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "unprognostic (3.75e-3)" "unprognostic (6.63e-3)" "unprognostic (1.02e-1)" "unprognostic (8.19e-4)" "unprognostic (2.38e-1)" "unprognostic (5.26e-2)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (2.04e-1)" ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 516.1;Kupffer cells: 213.3;Microglial cells: 586.5" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 104.1;Myeloma: 146.5" "Liver - Hepatocytes, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 51: Myeloma - Humoral immune response" "Cluster 29: Hepatocytes - Metabolism" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 528.9;Hepatocytes: 575.5;Intestinal goblet cells: 633.6;Late spermatids: 2035.1;Paneth cells: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 314.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 189.5;parathyroid gland: 78.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 76.0;Respiratory ciliated cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 29: Hepatocytes - Metabolism" Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1072.1" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 1791.1" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Cancer enriched" "Detected in some" 8 "liver cancer: 9.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 1200000 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 142.2" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 10.6;lymphoma: 4.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 29: Hepatocytes - Metabolism" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" TIGD2 ENSG00000180346 "Tigger transposable element derived 2" Q4W5G0 4 89111533-89114901 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 25.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.5;Hepatocytes: 20.9;Syncytiotrophoblasts: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 11.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 11.7" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054844, HPA071168" Uncertain Approved "Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Nuclear bodies" "HPA054844: AB_2682623, HPA071168: AB_2686353" "unprognostic (7.11e-2)" "unprognostic (8.02e-2)" "prognostic favorable (4.59e-4)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (5.42e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (8.47e-2)" "unprognostic (4.96e-2)" "unprognostic (9.83e-3)" "unprognostic (1.16e-1)" "unprognostic (8.94e-3)" "unprognostic (2.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.02e-4)" TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.3;Erythroid cells: 178.1;Hepatocytes: 235.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 71: Erythroid cells - Oxygen transport" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" TLCD4-RWDD3 TMEM56-RWDD3 ENSG00000271092 "TLCD4-RWDD3 readthrough" 1 95117923-95247225 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.2;Erythroid cells: 4.3;Excitatory neurons: 3.7;Inhibitory neurons: 4.4;Oligodendrocyte precursor cells: 5.8;Oligodendrocytes: 3.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.77e-3)" "unprognostic (4.35e-2)" "unprognostic (7.05e-2)" "unprognostic (1.70e-1)" "unprognostic (4.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.29e-2)" "unprognostic (3.42e-1)" "unprognostic (2.72e-1)" "unprognostic (1.99e-1)" "unprognostic (1.42e-2)" TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 500.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1038.0;Paneth cells: 738.1;Proximal enterocytes: 1334.3;Proximal tubular cells: 883.1" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 34.0;Gastric cancer: 34.6;liver cancer: 13.0;lung cancer: 16.6;Neuroblastoma: 10.8;pancreatic cancer: 17.6;thyroid cancer: 16.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 59: Proximal enterocytes - Transmembrane transport" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1131.1;Paneth cells: 761.0;Proximal enterocytes: 939.4;Proximal tubular cells: 747.7;Schwann cells: 430.8" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 39.4" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" TMEM220 ENSG00000187824 "Transmembrane protein 220" Q6QAJ8 17 10699015-10730023 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 103.8" "Cell type enhanced" "Detected in many" "Early spermatids: 118.9;Hepatocytes: 186.4;Proximal enterocytes: 567.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 59: Proximal enterocytes - Transmembrane transport" "unprognostic (1.71e-2)" "unprognostic (4.60e-2)" "unprognostic (6.31e-3)" "unprognostic (4.04e-3)" "unprognostic (1.05e-3)" "unprognostic (1.84e-4)" "prognostic favorable (2.23e-5)" "unprognostic (4.58e-2)" "unprognostic (4.96e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.97e-1)" "unprognostic (4.34e-3)" "unprognostic (2.25e-1)" "unprognostic (2.63e-2)" "unprognostic (7.80e-3)" "unprognostic (5.97e-2)" TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 8 "Late spermatids: 1019.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 6: Late spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 104.0;Endothelial cells: 49.8;Gastric mucus-secreting cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986479-126203817 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 84.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030473 Approved "Nuclear bodies" Yes No "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 15: Non-specific - Protein binding" "Cluster 44: Photoreceptor cells - Visual perception" "Nuclear bodies" "HPA030473: AB_2673493" "unprognostic (2.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.44e-1)" "unprognostic (1.13e-2)" "unprognostic (7.62e-2)" "unprognostic (9.69e-2)" "unprognostic (2.12e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-2)" "unprognostic (5.73e-2)" "unprognostic (7.35e-2)" "unprognostic (1.06e-2)" "unprognostic (4.74e-3)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" TRPM8 ENSG00000144481 "Transient receptor potential cation channel subfamily M member 8" Q7Z2W7 2 233917373-234019522 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 57 "liver: 31.5;prostate: 80.2" "Group enriched" "Detected in some" 12 "Hepatocytes: 37.9;Prostatic glandular cells: 88.6" "Cancer enriched" "Detected in some" 27 "prostate cancer: 72.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 7.1;Myeloma: 8.3;prostate cancer: 13.6;skin cancer: 16.9" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: Skin cancer - Membrane components" "Cluster 73: Prostatic glandular cells - Transcription" "unprognostic (4.41e-3)" "unprognostic (7.91e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (4.60e-3)" "prognostic favorable (7.15e-4)" "unprognostic (3.28e-2)" "unprognostic (3.71e-1)" "unprognostic (9.88e-3)" "unprognostic (7.10e-3)" "unprognostic (4.69e-2)" "unprognostic (3.36e-5)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 439.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.5;urinary bladder: 12.0" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 103.5;Basal squamous epithelial cells: 213.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 38400 "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 22: Squamous epithelial cells - Keratinization" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 584.9;Hepatocytes: 430.3;Paneth cells: 294.4;Proximal enterocytes: 294.5" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" TTPAL "C20orf121, dJ179M20.3" ENSG00000124120 "Alpha tocopherol transfer protein like" Q9BTX7 20 44475874-44494603 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 28.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046957, HPA066532" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Golgi apparatus, Cytosol" "HPA046957: AB_10959741, HPA066532: AB_2685686" "unprognostic (8.71e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.47e-5)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.54e-1)" "unprognostic (1.64e-2)" "unprognostic (2.32e-1)" "unprognostic (5.06e-2)" "unprognostic (4.50e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.09e-5)" "unprognostic (2.09e-2)" "unprognostic (2.88e-1)" "unprognostic (2.24e-2)" "unprognostic (7.93e-2)" TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 170.1;monocytes: 171.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 114.6" "Group enriched" "Detected in all" 5 "granulocytes: 114.6;monocytes: 47.8" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 55: Non-specific - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.6;Early spermatids: 25.0;Gastric mucus-secreting cells: 14.3;Late spermatids: 35.9;Squamous epithelial cells: 16.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 254.4" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 36: Spermatids - Spermatogenesis" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 216.0" "Group enriched" "Detected in some" 7 "Hepatocytes: 136.9;Proximal tubular cells: 49.9" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Group enriched" "Detected in some" 14 "basophil: 2.1;neutrophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Sebaceous gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1400000 "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 60: Proximal tubular cells - Absorption" "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 337.9;Hepatocytes: 776.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 18.7;Cone photoreceptor cells: 10.3;Hepatocytes: 13.7;Rod photoreceptor cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.0" "Colon - Endothelial cells, Lung - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 44: Photoreceptor cells - Visual perception" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 38.8;Hepatocytes: 50.8;Inhibitory neurons: 35.1;Proximal tubular cells: 32.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: Non-specific - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favorable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" ZGPAT "dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP" ENSG00000197114 "Zinc finger CCCH-type and G-patch domain containing" Q8N5A5 20 63707465-63736142 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 123.5" "Cell type enhanced" "Detected in many" "B-cells: 9.7;Basal squamous epithelial cells: 12.3;Gastric mucus-secreting cells: 14.9;Plasma cells: 24.2;Squamous epithelial cells: 11.5;Thymic epithelial cells: 10.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA056705 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 61: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA056705: AB_2683213" "unprognostic (4.50e-2)" "unprognostic (2.74e-1)" "unprognostic (5.30e-2)" "unprognostic (4.42e-2)" "unprognostic (8.58e-2)" "prognostic favorable (6.17e-5)" "unprognostic (1.06e-1)" "unprognostic (6.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.54e-1)" "unprognostic (9.31e-3)" "unprognostic (1.60e-2)" "unprognostic (3.43e-3)" "unprognostic (1.37e-1)" "unprognostic (4.11e-2)" "unprognostic (1.24e-1)" "unprognostic (9.86e-3)" ZNF799 "HIT-40, MGC71805, ZNF842" ENSG00000196466 "Zinc finger protein 799" Q96GE5 19 12390016-12401271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "HPA003150, HPA018683" Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "Centriolar satellite" "HPA003150: AB_1080725, HPA018683: AB_2669920" "unprognostic (2.96e-1)" "unprognostic (1.10e-1)" "unprognostic (8.84e-2)" "prognostic favorable (2.39e-4)" "unprognostic (3.63e-2)" "unprognostic (5.18e-3)" "unprognostic (3.02e-1)" "unprognostic (8.83e-3)" "unprognostic (4.47e-5)" "unprognostic (1.45e-1)" "unprognostic (5.56e-3)" "unprognostic (6.55e-2)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.04e-1)" "unprognostic (8.91e-3)" "unprognostic (1.23e-3)" ZXDB ZNF905 ENSG00000198455 "Zinc finger X-linked duplicated B" P98169 X 57592011-57597477 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 19.4;Suprabasal keratinocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA043789 Approved Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA043789: AB_2678673" "unprognostic (1.87e-1)" "unprognostic (3.22e-1)" "unprognostic (1.88e-1)" "unprognostic (8.61e-3)" "unprognostic (4.29e-2)" "unprognostic (2.80e-1)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (4.36e-1)" "unprognostic (9.04e-2)" "unprognostic (6.73e-2)" "unprognostic (2.16e-2)" "unprognostic (1.17e-3)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (4.02e-3)" "unprognostic (2.87e-3)"