Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CAMKK2	"CAMKK, CAMKKB, KIAA0787, MGC15254"	ENSG00000110931	"Calcium/calmodulin dependent protein kinase kinase 2"	Q96RR4	12	121237675-121298308	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 135.4"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 63.9;Late spermatids: 90.4"	"Cancer enriched"	"Detected in all"	5	"prostate cancer: 56.3"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"classical monocyte: 32.7;eosinophil: 62.1;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.2;non-classical monocyte: 39.5"	"Group enriched"	"Detected in all"	5	"dendritic cells: 15.9;granulocytes: 62.1;monocytes: 42.3"	"Low cancer specificity"	"Detected in all"			"Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017389, HPA063713"	Approved	Supported	Supported	Cytosol		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 38: Neurons - Neuronal signaling"	Cytosol		"HPA017389: AB_1845956, HPA063713: "	"unprognostic (5.08e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.38e-1)"	"unprognostic (3.08e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.12e-1)"	"unprognostic (2.62e-3)"	"unprognostic (2.80e-2)"	"unprognostic (1.93e-1)"	"unprognostic (7.76e-2)"	"unprognostic (5.01e-2)"	"unprognostic (1.70e-1)"	"unprognostic (1.75e-1)"	"unprognostic (4.13e-1)"	"unprognostic (3.34e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.38e-1)"
CPLX4	CPX-IV	ENSG00000166569	"Complexin 4"	Q7Z7G2	18	59275156-59318649	"Predicted intracellular proteins"	"Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision"			"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	287	"retina: 314.9"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 80.6;Cone photoreceptor cells: 377.4;Rod photoreceptor cells: 151.1"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"cerebellum: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			HPA047627	Enhanced					NA	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 47: Retina - Visual perception"	"Cluster 44: Photoreceptor cells - Visual perception"			"HPA047627: "					"unprognostic (1.85e-1)"		"unprognostic (4.46e-1)"			"unprognostic (4.20e-2)"		"unprognostic (4.05e-2)"		"unprognostic (9.90e-3)"			
SMIM18		ENSG00000253457	"Small integral membrane protein 18"	P0DKX4	8	30638580-30646064	"Predicted intracellular proteins, Predicted membrane proteins"				"Evidence at protein level"	"Evidence at protein level"	"No human protein/transcript evidence"	"Evidence at transcript level"	"Tissue enhanced"	"Detected in some"		"brain: 4.4;pituitary gland: 5.4;retina: 3.7"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 9.4;Excitatory neurons: 2.8;Horizontal cells: 7.7;Inhibitory neurons: 5.1;Microglial cells: 4.6;Oligodendrocyte precursor cells: 5.3;Proximal tubular cells: 3.5"	"Cancer enriched"	"Detected in single"	8	"glioma: 1.9"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cancer enriched"	"Detected in some"	5	"Neuroblastoma: 5.7"	"Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA066648	Supported		Uncertain	Nucleoplasm,Centrosome		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 77: Retina - Visual perception"	"Cluster 7: Neuronal cell lines - Stereocilium"	"Cluster 35: Bipolar cells - Visual perception"	Nucleoplasm	Centrosome	"HPA066648: AB_2685697"	"unprognostic (2.19e-2)"	"unprognostic (9.37e-2)"	"unprognostic (3.31e-1)"	"unprognostic (4.24e-2)"	"unprognostic (1.66e-1)"	"unprognostic (2.60e-1)"		"unprognostic (7.29e-2)"	"unprognostic (4.70e-1)"	"unprognostic (8.91e-3)"	"unprognostic (1.05e-1)"	"unprognostic (2.36e-1)"	"unprognostic (6.08e-2)"	"unprognostic (4.01e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.25e-1)"	"unprognostic (4.14e-1)"
SPTBN4	"KIAA1642, SPTBN3"	ENSG00000160460	"Spectrin beta, non-erythrocytic 4"	Q9H254	19	40466241-40576464	"Disease related genes, Plasma proteins, Predicted intracellular proteins"		"Actin capping, Actin-binding"	"Deafness, Disease variant, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"brain: 20.1;pituitary gland: 7.8"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 47.1;Bipolar cells: 51.0;Excitatory neurons: 206.4;Horizontal cells: 98.7;Inhibitory neurons: 190.5;Oligodendrocyte precursor cells: 44.3;Rod photoreceptor cells: 63.5"	"Low cancer specificity"	"Detected in some"			"Region enhanced"	"Detected in many"		"cerebral cortex: 20.1"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Neuroblastoma: 5.0"	"Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054481	Enhanced		Approved	Nucleoplasm,Nucleoli		NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 21: Neuroblastoma - Neuronal signaling"	"Cluster 37: Neurons - Neuronal signaling"	Nucleoli	Nucleoplasm	"HPA054481: AB_2682502"	"unprognostic (1.97e-3)"	"unprognostic (1.02e-1)"	"unprognostic (5.65e-4)"	"unprognostic (3.72e-4)"	"unprognostic (7.79e-3)"	"unprognostic (9.77e-2)"	"unprognostic (2.62e-1)"	"unprognostic (2.50e-2)"	"unprognostic (3.19e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.78e-4)"	"unprognostic (4.54e-1)"	"unprognostic (2.55e-2)"	"unprognostic (6.79e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.02e-1)"
TRIM46	"FLJ23229, TRIFIC"	ENSG00000163462	"Tripartite motif containing 46"	Q7Z4K8	1	155173787-155184971	"Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 10.1"	"Cell type enhanced"	"Detected in some"		"Excitatory neurons: 12.9;Horizontal cells: 10.9;Inhibitory neurons: 9.5;Late spermatids: 9.6;Oligodendrocytes: 9.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 9.8"	"Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA055583	Enhanced					NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 65: Brain - Ion transport"	"Cluster 21: Neuroblastoma - Neuronal signaling"	"Cluster 30: Breast - Lactation"			"HPA055583: AB_2732599"	"unprognostic (1.06e-1)"	"unprognostic (5.07e-2)"	"unprognostic (2.86e-2)"	"prognostic unfavorable (2.61e-7)"	"unprognostic (1.75e-1)"	"unprognostic (7.26e-2)"	"unprognostic (1.59e-2)"	"unprognostic (4.65e-2)"	"unprognostic (4.09e-1)"	"unprognostic (2.88e-2)"	"unprognostic (2.18e-3)"	"unprognostic (1.24e-1)"	"unprognostic (2.29e-12)"	"unprognostic (8.58e-2)"	"unprognostic (2.45e-1)"	"unprognostic (2.70e-1)"	"unprognostic (1.72e-2)"
TTC21B	"FAP60, FLA17, FLJ11457, IFT139B, JBTS11, NPHP12, THM1"	ENSG00000123607	"Tetratricopeptide repeat domain 21B"	Q7Z4L5	2	165857475-165953851	"Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Endometrial ciliated cells: 111.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA073293	Supported		Approved	"Centriolar satellite,Cytosol"		NA	No			"Cluster 38: Basophils - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 56: Ciliated cells - Cilium assembly"	"Centriolar satellite"	Cytosol	"HPA073293: "	"unprognostic (1.63e-2)"	"unprognostic (1.17e-1)"	"unprognostic (3.10e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.96e-1)"	"unprognostic (2.51e-1)"	"unprognostic (7.09e-3)"	"unprognostic (2.81e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.57e-2)"	"unprognostic (3.52e-2)"	"unprognostic (3.29e-1)"	"prognostic unfavorable (1.36e-4)"	"unprognostic (1.32e-1)"	"unprognostic (1.55e-1)"	"unprognostic (2.37e-2)"	"unprognostic (1.84e-2)"
VCAN	"CSPG2, PG-M"	ENSG00000038427	Versican	P13611	5	83471618-83582303	"Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"			Cataract	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 969.7;Granulosa cells: 1101.8;Kupffer cells: 1041.7;Macrophages: 573.9;Oligodendrocyte precursor cells: 1575.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"classical monocyte: 240.0;myeloid DC: 88.9"	"Group enriched"	"Detected in many"	20	"dendritic cells: 88.9;monocytes: 240.0"	"Cancer enhanced"	"Detected in many"		"Kidney cancer: 172.8"	"Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004726, CAB008979"	Supported		Approved	Vesicles	"Secreted to blood"	NA	NA		12000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 68: Kidney - Mixed function"	"Cluster 33: Macrophages - Degranulation"	Vesicles		"CAB008979: , HPA004726: AB_1080561"	"unprognostic (7.90e-2)"	"unprognostic (9.03e-3)"	"unprognostic (7.09e-2)"	"unprognostic (6.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (4.49e-2)"	"unprognostic (1.23e-2)"	"unprognostic (1.17e-2)"	"prognostic unfavorable (7.59e-4)"	"unprognostic (4.36e-3)"	"unprognostic (2.68e-3)"	"unprognostic (2.05e-1)"	"prognostic unfavorable (5.17e-4)"	"prognostic unfavorable (1.41e-4)"	"unprognostic (1.15e-1)"	"unprognostic (4.44e-2)"	"unprognostic (5.30e-3)"
ZP2	ZPA	ENSG00000103310	"Zona pellucida glycoprotein 2"	Q05996	16	21197450-21214510	"Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins"	Fertilization	Receptor		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	8	"brain: 4.8"	"Group enriched"	"Detected in some"	7	"Proximal enterocytes: 6.8;Serous glandular cells: 2.4"	"Not detected"	"Not detected"			"Region enriched"	"Detected in single"	15	"cerebellum: 4.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA011296	Enhanced				"Secreted in female reproductive system"	NA	NA				"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 11: Lymphoma - Adaptive immune response"	"Cluster 59: Proximal enterocytes - Transmembrane transport"			"HPA011296: AB_1859485"	"unprognostic (2.35e-2)"		"unprognostic (3.12e-2)"			"unprognostic (6.60e-2)"		"unprognostic (9.83e-2)"			"unprognostic (3.44e-3)"	"unprognostic (3.12e-1)"		"unprognostic (1.66e-1)"	"unprognostic (4.41e-2)"