Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
AARS1	"AARS, AlaRS, CMT2N"	ENSG00000090861	"Alanyl-tRNA synthetase 1"	P49588	16	70251983-70289707	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding"	"Charcot-Marie-Tooth disease, Disease variant, Epilepsy, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB034261, HPA040870, HPA044223"	Supported		Supported	Cytosol		NA	NA		620000	"Cluster 27: Non-specific - Gene expression"	"Cluster 22: Non-specific - Unknown function"	"Cluster 36: Non-specific - Unknown function"	"Cluster 40: Plasma cells - Humoral immune response"	Cytosol		"CAB034261: AB_1562673, HPA040870: AB_10794995, HPA044223: AB_2678862"	"unprognostic (1.98e-2)"	"unprognostic (6.87e-2)"	"unprognostic (8.02e-2)"	"unprognostic (5.72e-2)"	"unprognostic (3.58e-1)"	"unprognostic (2.50e-2)"	"unprognostic (7.99e-2)"	"unprognostic (2.36e-1)"	"unprognostic (1.99e-1)"	"unprognostic (1.76e-1)"	"unprognostic (8.33e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.42e-2)"	"unprognostic (3.75e-2)"	"unprognostic (2.05e-3)"	"unprognostic (8.22e-2)"	"unprognostic (3.83e-3)"
CARS1	CARS	ENSG00000110619	"Cysteinyl-tRNA synthetase 1"	P49589	11	3000922-3057613	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 158.3;Respiratory ciliated cells: 152.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737"	Enhanced		Enhanced	Cytosol		NA	NA		200000	"Cluster 14: Monocytes - Unknown function"	"Cluster 50: Non-specific - Ribosome"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 56: Ciliated cells - Cilium assembly"	Cytosol		"CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033"	"unprognostic (9.10e-3)"	"unprognostic (1.83e-1)"	"unprognostic (4.16e-3)"	"unprognostic (1.43e-1)"	"unprognostic (1.00e-2)"	"unprognostic (7.97e-2)"	"prognostic unfavorable (5.16e-4)"	"unprognostic (1.41e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.00e-2)"	"unprognostic (5.51e-2)"	"unprognostic (2.45e-1)"	"prognostic unfavorable (0.00e+0)"	"unprognostic (5.37e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.48e-1)"	"unprognostic (3.46e-1)"
DARS1	DARS	ENSG00000115866	"Aspartyl-tRNA synthetase 1"	P14868	2	135905881-135986100	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA020451, HPA029804, HPA029805"	Enhanced		Enhanced	Cytosol		NA	NA		210000	"Cluster 30: Non-specific - Translation"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 16: Non-specific - RNA binding"	Cytosol		"HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994"	"unprognostic (6.13e-2)"	"unprognostic (8.16e-3)"	"unprognostic (5.54e-2)"	"unprognostic (5.36e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.91e-2)"	"prognostic unfavorable (2.39e-6)"	"unprognostic (2.98e-3)"	"prognostic unfavorable (7.57e-4)"	"unprognostic (6.00e-3)"	"prognostic unfavorable (6.54e-4)"	"unprognostic (2.78e-1)"	"prognostic unfavorable (1.24e-5)"	"unprognostic (1.04e-1)"	"unprognostic (9.12e-2)"	"unprognostic (3.94e-3)"	"unprognostic (2.00e-1)"
EPRS1	"EARS, EPRS, GLUPRORS, PARS, QARS, QPRS"	ENSG00000136628	"Glutamyl-prolyl-tRNA synthetase 1"	P07814	1	219968600-220046530	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis, Translation regulation"	"Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding"	"Disease variant, Leukodystrophy, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Serous glandular cells: 223.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA026490, HPA030052"	Enhanced		Enhanced	Cytosol		NA	NA		360000	"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: Non-specific - RNA binding"	"Cluster 21: Serous glandular cells - Salivary secretion"	Cytosol		"HPA026490: AB_1855979, HPA030052: AB_10601466"	"prognostic unfavorable (7.25e-4)"	"unprognostic (1.19e-2)"	"unprognostic (3.94e-2)"	"unprognostic (2.60e-2)"	"unprognostic (7.98e-3)"	"unprognostic (1.12e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.32e-1)"	"unprognostic (1.76e-1)"	"unprognostic (1.30e-1)"	"unprognostic (7.13e-2)"	"unprognostic (5.12e-2)"	"unprognostic (2.32e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.38e-1)"	"unprognostic (2.85e-1)"	"prognostic unfavorable (2.62e-4)"
FARSA	"CML33, FARSL, FARSLA"	ENSG00000179115	"Phenylalanyl-tRNA synthetase subunit alpha"	Q9Y285	19	12922479-12934037	"Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001911	Enhanced		Approved	Cytosol		NA	NA		55000	"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 16: Non-specific - RNA binding"	Cytosol		"HPA001911: AB_1848427"	"unprognostic (1.52e-1)"	"prognostic favorable (8.23e-4)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (9.22e-4)"	"unprognostic (1.16e-2)"	"unprognostic (1.28e-1)"	"unprognostic (4.93e-3)"	"unprognostic (5.76e-2)"	"unprognostic (2.86e-1)"	"unprognostic (1.24e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.45e-2)"	"unprognostic (1.45e-3)"	"prognostic favorable (8.32e-4)"	"unprognostic (2.59e-1)"	"unprognostic (8.25e-2)"	"unprognostic (1.84e-2)"
FARSB	"FARSLB, FRSB, PheHB"	ENSG00000116120	"Phenylalanyl-tRNA synthetase subunit beta"	Q9NSD9	2	222566899-222656092	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Intellectual disability, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036677, HPA036678, HPA061398"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA		28000	"Cluster 27: Non-specific - Gene expression"	"Cluster 59: Non-specific - Translation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 18: Non-specific - Mixed function"	Nucleoplasm	Cytosol	"HPA036677: AB_2675242, HPA036678: AB_10673504, HPA061398: AB_2684504"	"unprognostic (9.95e-3)"	"unprognostic (1.86e-3)"	"unprognostic (7.02e-2)"	"unprognostic (7.42e-3)"	"unprognostic (1.90e-1)"	"unprognostic (1.15e-1)"	"prognostic unfavorable (6.45e-10)"	"unprognostic (8.89e-3)"	"unprognostic (4.51e-2)"	"unprognostic (3.63e-2)"	"unprognostic (5.25e-3)"	"unprognostic (6.25e-2)"	"prognostic unfavorable (3.21e-5)"	"unprognostic (1.36e-1)"	"unprognostic (4.38e-2)"	"unprognostic (2.10e-1)"	"prognostic unfavorable (1.25e-4)"
GARS1	"CMT2D, DSMAV, GARS, GlyRS, SMAD1"	ENSG00000106105	"Glycyl-tRNA synthetase 1"	P41250	7	30580533-30634033	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase"	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017896, HPA019097"	Enhanced		Supported	Cytosol	"Intracellular and membrane"	NA	NA		560000	"Cluster 44: Non-specific - Transcription"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 16: Non-specific - RNA binding"	Cytosol		"HPA017896: AB_1849478, HPA019097: AB_1849480"	"prognostic unfavorable (1.02e-4)"	"unprognostic (2.46e-2)"	"unprognostic (5.45e-2)"	"prognostic unfavorable (8.48e-4)"	"unprognostic (2.04e-1)"	"unprognostic (1.57e-3)"	"prognostic unfavorable (8.95e-5)"	"unprognostic (7.31e-3)"	"unprognostic (4.76e-1)"	"unprognostic (4.00e-3)"	"unprognostic (1.77e-1)"	"unprognostic (4.45e-2)"	"prognostic unfavorable (1.70e-5)"	"unprognostic (3.92e-1)"	"unprognostic (3.40e-2)"	"unprognostic (6.32e-2)"	"prognostic unfavorable (3.04e-5)"
HARS1	"HARS, HisRS, USH3B"	ENSG00000170445	"Histidyl-tRNA synthetase 1"	P12081	5	140673035-140691537	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA036539	Approved		Enhanced	Cytosol		NA	NA		190000	"Cluster 27: Non-specific - Gene expression"	"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 57: Non-specific - Translation"	"Cluster 70: Basal prostatic cells - Lipid metabolism"	Cytosol		"HPA036539: AB_10669796"	"unprognostic (9.35e-2)"	"unprognostic (9.95e-2)"	"unprognostic (1.62e-3)"	"unprognostic (1.65e-2)"	"unprognostic (2.33e-1)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (1.96e-7)"	"unprognostic (6.50e-2)"	"unprognostic (1.46e-1)"	"unprognostic (3.82e-2)"	"unprognostic (1.28e-2)"	"unprognostic (2.40e-1)"	"unprognostic (3.46e-2)"	"unprognostic (2.99e-1)"	"unprognostic (1.25e-1)"	"unprognostic (6.26e-2)"	"unprognostic (1.36e-1)"
IARS1	"IARS, ILRS"	ENSG00000196305	"Isoleucyl-tRNA synthetase 1"	P41252	9	92210207-92293756	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA029806	Approved		Approved	Nucleoplasm,Cytosol		NA	NA		100000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 16: Non-specific - RNA binding"	"Nucleoplasm, Cytosol"		"HPA029806: AB_10601818"	"unprognostic (1.32e-3)"	"unprognostic (2.94e-2)"	"unprognostic (2.27e-2)"	"unprognostic (8.23e-2)"	"unprognostic (1.33e-1)"	"unprognostic (1.26e-2)"	"prognostic unfavorable (4.98e-7)"	"unprognostic (2.00e-2)"	"unprognostic (3.80e-2)"	"unprognostic (1.10e-1)"	"unprognostic (4.96e-2)"	"unprognostic (3.67e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.88e-2)"	"unprognostic (4.71e-2)"	"unprognostic (2.21e-1)"	"unprognostic (7.76e-3)"
KARS1	"DFNB89, KARS, KARS2"	ENSG00000065427	"Lysyl-tRNA synthetase 1"	Q15046	16	75627474-75648643	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Host-virus interaction, Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase, Transferase"	"Charcot-Marie-Tooth disease, Deafness, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 296.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041345, HPA041550"	Enhanced		Supported	"Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		82000	"Cluster 27: Non-specific - Gene expression"	"Cluster 52: Non-specific - Ribosome"	"Cluster 36: Non-specific - Unknown function"	"Cluster 18: Non-specific - Mixed function"	Cytosol	"Plasma membrane"	"HPA041345: AB_10795589, HPA041550: AB_10794520"	"unprognostic (1.56e-1)"	"unprognostic (7.93e-2)"	"unprognostic (3.36e-2)"	"unprognostic (1.02e-2)"	"unprognostic (5.39e-2)"	"prognostic unfavorable (8.84e-6)"	"unprognostic (6.24e-3)"	"unprognostic (8.97e-3)"	"unprognostic (1.18e-1)"	"unprognostic (9.11e-3)"	"unprognostic (8.71e-3)"	"unprognostic (8.46e-2)"	"unprognostic (7.86e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.03e-1)"	"unprognostic (3.07e-2)"	"unprognostic (2.13e-1)"
LARS1	"FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS"	ENSG00000133706	"Leucyl-tRNA synthetase 1"	Q9P2J5	5	146110566-146182696	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036424, HPA040881"	Supported		Approved	"Nuclear bodies,Cytosol"		NA	NA		110000	"Cluster 7: Monocytes - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 57: Non-specific - Translation"	"Cluster 16: Non-specific - RNA binding"	"Nuclear bodies, Cytosol"		"HPA036424: AB_10670102, HPA040881: AB_2677185"	"unprognostic (2.20e-2)"	"unprognostic (1.87e-1)"	"unprognostic (2.38e-3)"	"unprognostic (1.92e-1)"	"unprognostic (2.69e-1)"	"unprognostic (3.39e-1)"	"prognostic unfavorable (3.78e-5)"	"unprognostic (8.17e-2)"	"unprognostic (2.72e-1)"	"unprognostic (6.80e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.60e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.13e-1)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (2.98e-4)"	"unprognostic (2.96e-2)"
MARS1	"CMT2U, MARS, MetRS, SPG70"	ENSG00000166986	"Methionyl-tRNA synthetase 1"	P56192	12	57475445-57517569	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding"	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004125, CAB017097"	Supported	Approved	Enhanced	Cytosol		NA	NA		23000	"Cluster 27: Non-specific - Gene expression"	"Cluster 35: Non-specific - Unknown function"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 18: Non-specific - Mixed function"	Cytosol		"CAB017097: , HPA004125: AB_1079312"	"prognostic unfavorable (1.73e-4)"	"unprognostic (2.21e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.09e-1)"	"unprognostic (1.57e-2)"	"unprognostic (4.90e-3)"	"prognostic unfavorable (4.55e-7)"	"unprognostic (8.47e-2)"	"unprognostic (1.73e-1)"	"unprognostic (4.03e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.77e-2)"	"prognostic unfavorable (1.59e-4)"	"unprognostic (1.13e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.06e-2)"
MTFMT	FMT1	ENSG00000103707	"Mitochondrial methionyl-tRNA formyltransferase"	Q96DP5	15	65001512-65029639	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	Transferase	"Disease variant, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 49.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA040710	Uncertain		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 35: Non-specific - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 37: Neurons - Neuronal signaling"	Nucleoplasm	Cytosol	"HPA040710: AB_10794879"	"unprognostic (1.20e-1)"	"unprognostic (2.72e-2)"	"unprognostic (9.28e-3)"	"unprognostic (4.35e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.42e-2)"	"unprognostic (6.63e-2)"	"unprognostic (2.02e-1)"	"unprognostic (6.95e-2)"	"unprognostic (2.18e-2)"	"unprognostic (2.41e-2)"	"unprognostic (1.78e-1)"	"prognostic favorable (3.31e-8)"	"unprognostic (2.75e-2)"	"unprognostic (4.06e-2)"	"unprognostic (3.26e-1)"	"unprognostic (1.85e-2)"
NARS1	NARS	ENSG00000134440	"Asparaginyl-tRNA synthetase 1"	O43776	18	57600656-57622213	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Epilepsy, Intellectual disability, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 410.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB034257, HPA040017"	Enhanced		Supported	Cytosol		NA	NA		76000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 16: Non-specific - RNA binding"	Cytosol		"CAB034257: AB_2151043, HPA040017: AB_2676801"	"unprognostic (9.85e-2)"	"unprognostic (1.88e-1)"	"unprognostic (3.86e-3)"	"unprognostic (1.68e-1)"	"unprognostic (2.61e-1)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (1.23e-7)"	"unprognostic (1.78e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.62e-2)"	"unprognostic (1.98e-1)"	"unprognostic (8.82e-2)"	"prognostic favorable (1.73e-7)"	"unprognostic (1.24e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.51e-1)"
QARS1	QARS	ENSG00000172053	"Glutaminyl-tRNA synthetase 1"	P47897	3	49095932-49105130	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Epilepsy, Primary microcephaly"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 578.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036986, HPA036987"	Enhanced		Enhanced	Cytosol		No	No		58000	"Cluster 27: Non-specific - Gene expression"	"Cluster 59: Non-specific - Translation"	"Cluster 57: Non-specific - Translation"	"Cluster 6: Late spermatids - Spermatogenesis"	Cytosol		"HPA036986: AB_10672344, HPA036987: AB_2675418"	"prognostic favorable (1.43e-4)"	"unprognostic (1.96e-1)"	"unprognostic (7.31e-2)"	"unprognostic (1.10e-2)"	"unprognostic (5.13e-3)"	"unprognostic (6.62e-3)"	"unprognostic (6.53e-3)"	"unprognostic (1.52e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.51e-1)"	"unprognostic (4.33e-1)"	"unprognostic (9.14e-2)"	"prognostic favorable (5.60e-6)"	"unprognostic (2.73e-3)"	"unprognostic (1.65e-1)"	"unprognostic (2.74e-2)"	"unprognostic (3.11e-1)"
RARS1	"DALRD1, RARS"	ENSG00000113643	"Arginyl-tRNA synthetase 1"	P54136	5	168486451-168519301	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Leukodystrophy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003979, HPA004130"	Approved		Supported	Nucleoplasm,Nucleoli,Cytosol		NA	NA		74000	"Cluster 27: Non-specific - Gene expression"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 57: Non-specific - Translation"	"Cluster 18: Non-specific - Mixed function"	Cytosol	"Nucleoplasm, Nucleoli"	"HPA003979: AB_1856083, HPA004130: AB_1856084"	"unprognostic (1.06e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.74e-3)"	"unprognostic (2.82e-2)"	"unprognostic (2.50e-1)"	"prognostic unfavorable (7.59e-5)"	"prognostic unfavorable (1.10e-8)"	"unprognostic (3.26e-3)"	"unprognostic (5.16e-1)"	"unprognostic (4.22e-2)"	"unprognostic (2.92e-2)"	"unprognostic (4.27e-2)"	"unprognostic (5.43e-2)"	"unprognostic (6.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (2.39e-1)"	"unprognostic (1.33e-2)"
SARS1	"SARS, SERS"	ENSG00000031698	"Seryl-tRNA synthetase 1"	P49591	1	109213918-109238182	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis, Transcription, Transcription regulation"	"Aminoacyl-tRNA synthetase, DNA-binding, Ligase"	"Disease variant, Epilepsy, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016939, HPA064668"	Approved		Enhanced	Cytosol		NA	NA		330000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 50: Non-specific - Ribosome"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 18: Non-specific - Mixed function"	Cytosol		"HPA016939: AB_1856585, HPA064668: AB_2685316"	"unprognostic (4.92e-2)"	"unprognostic (2.61e-1)"	"unprognostic (5.87e-2)"	"unprognostic (6.78e-2)"	"prognostic favorable (9.47e-4)"	"prognostic unfavorable (5.75e-4)"	"prognostic unfavorable (6.13e-5)"	"unprognostic (3.02e-1)"	"unprognostic (1.77e-1)"	"unprognostic (2.68e-2)"	"unprognostic (3.23e-1)"	"unprognostic (2.06e-1)"	"unprognostic (1.69e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.45e-3)"
TARS1	TARS	ENSG00000113407	"Threonyl-tRNA synthetase 1"	P26639	5	33440696-33468091	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA037425	Approved		Approved	"Actin filaments,Cytosol"		NA	NA		580000	"Cluster 15: NK-cells - Transcription"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 40: Non-specific - Enzymes"	"Cluster 3: Suprabasal keratinocytes - Cornification"	Cytosol	"Actin filaments"	"HPA037425: AB_10672279"	"prognostic unfavorable (6.14e-5)"	"unprognostic (5.13e-2)"	"unprognostic (9.04e-2)"	"prognostic unfavorable (5.17e-4)"	"unprognostic (9.10e-2)"	"unprognostic (1.07e-3)"	"prognostic unfavorable (9.88e-7)"	"unprognostic (1.43e-1)"	"unprognostic (1.61e-1)"	"unprognostic (2.65e-3)"	"unprognostic (5.97e-3)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (9.63e-4)"	"unprognostic (1.37e-1)"	"unprognostic (5.15e-2)"	"unprognostic (1.18e-1)"	"unprognostic (7.25e-2)"
VARS1	"VARS, VARS2"	ENSG00000204394	"Valyl-tRNA synthetase 1"	P26640	6	31777518-31795752	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Epilepsy, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 138.6;Late spermatids: 263.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046710	Approved		Enhanced	Cytosol		NA	NA		110000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 71: Testis - DNA repair"	"Cluster 15: Non-specific - Protein binding"	"Cluster 36: Spermatids - Spermatogenesis"	Cytosol		"HPA046710: AB_2679765"	"unprognostic (1.86e-2)"	"prognostic unfavorable (7.25e-4)"	"unprognostic (2.19e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.49e-2)"	"unprognostic (3.43e-2)"	"prognostic unfavorable (1.86e-4)"	"prognostic unfavorable (6.90e-4)"	"unprognostic (3.20e-1)"	"unprognostic (2.76e-1)"	"unprognostic (4.72e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.09e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.85e-2)"	"unprognostic (2.59e-1)"
WARS1	"IFI53, IFP53, WARS"	ENSG00000140105	"Tryptophanyl-tRNA synthetase 1"	P23381	14	100333790-100376805	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Angiogenesis, Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase"	"Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"placenta: 324.4"	"Cell type enhanced"	"Detected in all"		"monocytes: 336.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"intermediate monocyte: 1345.3;non-classical monocyte: 1608.2"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005573, HPA018944"	Enhanced		Enhanced	Cytosol		No	No		49000000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 66: Endothelial cells - Angiogenesis"	Cytosol		"HPA005573: AB_2667366, HPA018944: AB_2669986"	"unprognostic (5.36e-2)"	"unprognostic (5.98e-2)"	"unprognostic (3.99e-2)"	"unprognostic (1.54e-1)"	"unprognostic (2.30e-1)"	"unprognostic (9.25e-2)"	"prognostic unfavorable (7.88e-4)"	"unprognostic (5.14e-2)"	"unprognostic (4.26e-2)"	"prognostic favorable (1.94e-4)"	"unprognostic (4.84e-2)"	"unprognostic (3.21e-1)"	"unprognostic (3.53e-3)"	"unprognostic (1.37e-1)"	"unprognostic (9.45e-2)"	"unprognostic (1.62e-1)"	"unprognostic (5.92e-3)"
YARS1	"tyrRS, YARS, YRS, YTS"	ENSG00000134684	"Tyrosyl-tRNA synthetase 1"	P54577	1	32775237-32817380	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Protein biosynthesis"	"Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding"	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017936, HPA018950, HPA018954"	Enhanced		Enhanced	Cytosol		No	No		1400000	"Cluster 48: NK-cells - Unknown function"	"Cluster 22: Non-specific - Unknown function"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 40: Plasma cells - Humoral immune response"	Cytosol		"HPA017936: AB_1858916, HPA018950: AB_1858919, HPA018954: AB_1858915"	"unprognostic (4.05e-2)"	"unprognostic (2.52e-1)"	"unprognostic (4.21e-1)"	"unprognostic (4.78e-2)"	"unprognostic (9.54e-2)"	"unprognostic (3.38e-3)"	"prognostic unfavorable (6.97e-11)"	"unprognostic (5.05e-2)"	"unprognostic (6.29e-2)"	"unprognostic (1.93e-1)"	"unprognostic (1.81e-3)"	"unprognostic (4.96e-2)"	"prognostic unfavorable (1.02e-11)"	"unprognostic (3.57e-3)"	"unprognostic (1.02e-1)"	"unprognostic (4.94e-2)"	"prognostic unfavorable (6.57e-4)"
