Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Group enriched" "Detected in some" 5 "Early spermatids: 42.3;Hepatocytes: 124.5" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 46.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.2;Breast glandular cells: 6.2;Early spermatids: 3.4;Hepatocytes: 3.8;Prostatic glandular cells: 5.3;Spermatocytes: 3.2" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "breast cancer: 10.6;prostate cancer: 5.3" "Adipose visceral - Adipocytes (Visceral), Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 65: Breast cancer - Unknown function" "Cluster 73: Prostatic glandular cells - Transcription" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 223.3;Distal enterocytes: 196.7;Gastric mucus-secreting cells: 231.9;Hepatocytes: 152.3;Late spermatids: 130.5;Paneth cells: 185.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 61: Liver - Metabolism" "Cluster 50: Enterocytes - Absorption" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 36.4;Sertoli cells: 30.4;Syncytiotrophoblasts: 26.8" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 325.3;Hepatocytes: 791.9;Proximal enterocytes: 428.9;Proximal tubular cells: 528.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Excitatory neurons: 13.6;Inhibitory neurons: 11.7;Oligodendrocyte precursor cells: 8.2;Oligodendrocytes: 14.2;Proximal tubular cells: 5.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.4;Hepatocytes: 29.0;Proximal tubular cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 30.2;Proximal enterocytes: 19.5;Proximal tubular cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 12.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 19: Macrophages - Innate immune response" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;kidney: 3.7;liver: 3.1;skeletal muscle: 4.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.2;Excitatory neurons: 2.7;Hepatocytes: 4.2;Inhibitory neurons: 2.8;Proximal tubular cells: 4.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.9" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 65: Breast cancer - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" "HPA058258: AB_2683656" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-2)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7" "Cell type enhanced" "Detected in many" "granulocytes: 344.2;Late spermatids: 162.6;Proximal enterocytes: 180.5;Proximal tubular cells: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.2;plasmacytoid DC: 35.7" "Group enriched" "Detected in many" 5 "dendritic cells: 35.7;NK-cells: 40.2" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 38: Non-specific - mRNA processing" "Cluster 60: Proximal tubular cells - Absorption" Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 93.9;Late spermatids: 92.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 50: Enterocytes - Absorption" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 191.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 252.6;Proximal enterocytes: 216.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 77.2;neutrophil: 113.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 113.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 50: Enterocytes - Absorption" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.6;Proximal enterocytes: 30.1;Proximal tubular cells: 40.8" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.8;liver cancer: 3.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Supported Peroxisomes NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 210.6" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 754.0;Hepatocytes: 4232.0;Thymic epithelial cells: 1166.4" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Endothelial cells" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 267.5;Enteroendocrine cells: 218.6;Exocrine glandular cells: 214.7;Gastric mucus-secreting cells: 676.7;Hepatocytes: 520.9;Undifferentiated cells: 308.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 54.4" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 5151.4" "Cell type enriched" "Detected in some" 35 "Hepatocytes: 1118.2" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 3.3" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 20000000 "Cluster 34: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favorable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 325.3" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 114.3;Basal respiratory cells: 78.0;Basal squamous epithelial cells: 58.9;Club cells: 53.8;Squamous epithelial cells: 237.5;Suprabasal keratinocytes: 203.9" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Esophageal cancer: 29.4;Gallbladder cancer: 98.7" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 74.0;Cardiomyocytes: 42.4;Syncytiotrophoblasts: 184.6" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA023062 Enhanced NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" ADO "C10orf22, FLJ14547" ENSG00000181915 "2-aminoethanethiol dioxygenase" Q96SZ5 10 62804720-62808479 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 181.8;Late spermatids: 318.0;Spermatocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039194, HPA040437" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 51: Late spermatids - Spermatogenesis" "HPA039194: AB_10794994, HPA040437: AB_10795633" "unprognostic (4.41e-2)" "unprognostic (1.44e-1)" "unprognostic (9.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.54e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.01e-5)" "unprognostic (4.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (4.24e-2)" "unprognostic (8.64e-2)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "unprognostic (7.46e-2)" "unprognostic (2.64e-1)" "unprognostic (4.59e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 388.0;Cholangiocytes: 196.3;Distal enterocytes: 190.9;Gastric mucus-secreting cells: 499.0;Proximal enterocytes: 373.1;Suprabasal keratinocytes: 540.4" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gallbladder cancer: 2640.5;liver cancer: 687.1" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 17.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 61: Liver - Metabolism" "Cluster 67: Syncytiotrophoblasts - Pregnancy" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.8;Basal respiratory cells: 234.6;Basal squamous epithelial cells: 354.3;Cholangiocytes: 231.0;Hepatocytes: 763.5" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 5 "Bladder cancer: 255.2;Esophageal cancer: 521.6;Gallbladder cancer: 849.0;Kidney cancer: 272.4;liver cancer: 827.9;lung cancer: 296.7" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.5;Basal respiratory cells: 145.1;Club cells: 133.3;Hepatocytes: 477.6;Squamous epithelial cells: 116.6" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 1225.3;Gallbladder cancer: 1163.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 380.9;Cholangiocytes: 313.7;Exocrine glandular cells: 438.2;Hepatocytes: 456.7;Proximal enterocytes: 617.1;Proximal tubular cells: 502.4" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1700.4" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 834.6" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.0;colorectal cancer: 4.5;liver cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 26: NCI-H716 - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138118305 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "liver: 426.9" "Cell type enhanced" "Detected in some" "Early spermatids: 48.7;Hepatocytes: 213.6;Late spermatids: 113.8" "Cancer enriched" "Detected in single" 77 "liver cancer: 20.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "liver cancer: 2.2" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057002 Enhanced Approved Nucleoplasm,Cytosol No NA 61000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm Cytosol "HPA057002: AB_2683308" "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "prognostic favorable (9.91e-5)" "unprognostic (6.11e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (6.87e-2)" "unprognostic (2.94e-1)" "unprognostic (9.68e-3)" "unprognostic (2.90e-1)" "unprognostic (5.80e-2)" "unprognostic (3.11e-1)" "unprognostic (1.67e-2)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 67.4;Ductal cells: 57.9;Hepatocytes: 116.1;Proximal tubular cells: 171.4;Theca cells: 66.7;Undifferentiated cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 60: Proximal tubular cells - Absorption" Mitochondria "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 994.8;Proximal tubular cells: 653.6" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 551.9;Basal respiratory cells: 376.7;Basal squamous epithelial cells: 249.1;Gastric mucus-secreting cells: 424.5;Respiratory ciliated cells: 376.2;Serous glandular cells: 212.8;Squamous epithelial cells: 370.3;Suprabasal keratinocytes: 936.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 3235.6" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 249.0;Basal squamous epithelial cells: 284.7;Squamous epithelial cells: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 61: Liver - Metabolism" "Cluster 22: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 460.1;Proximal tubular cells: 277.1;Syncytiotrophoblasts: 209.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cancer enhanced" "Detected in all" "Rhabdoid: 291.4" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 28: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 287.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 3: Suprabasal keratinocytes - Cornification" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.0;Hepatocytes: 18.7;Late spermatids: 15.0;Proximal tubular cells: 40.2" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Stomach - Chief cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 1052.0" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.5;Gastric cancer: 2.5;Kidney cancer: 2.6;liver cancer: 9.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Approved Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 567.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 48: Non-specific - RNA binding" "Cluster 19: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 223.9;Proximal enterocytes: 189.8;Proximal tubular cells: 777.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 45: Non-specific - Cell proliferation" "Cluster 60: Proximal tubular cells - Absorption" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" CBR4 "FLJ14431, SDR45C1" ENSG00000145439 "Carbonyl reductase 4" Q8N4T8 4 168863770-169010275 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037499 Supported NA NA 51000 "Cluster 18: Basophils - Vesicular transport" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 64: Non-specific - Transcription" "HPA037499: AB_10672386" "unprognostic (1.60e-1)" "unprognostic (8.25e-2)" "unprognostic (1.37e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (2.39e-2)" "unprognostic (2.41e-3)" "unprognostic (4.06e-2)" "unprognostic (1.29e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-1)" "unprognostic (6.64e-2)" "prognostic favorable (3.64e-14)" "unprognostic (1.97e-2)" "unprognostic (2.00e-1)" "unprognostic (1.81e-2)" "unprognostic (7.38e-3)" CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 174.2;Cytotrophoblasts: 322.8;Hepatocytes: 161.1;Leydig cells: 91.5;Syncytiotrophoblasts: 541.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 59: Fibroblasts - Metabolism" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" CH25H ENSG00000138135 "Cholesterol 25-hydroxylase" O95992 10 89205629-89207317 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 130.8;Basal squamous epithelial cells: 147.6;Macrophages: 45.2;monocytes: 166.4;Smooth muscle cells: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.5;Uterine cancer: 4.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "spinal cord: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 59: Fibroblasts - Metabolism" "Cluster 75: Myeloid cells - Innate immune response" "unprognostic (6.07e-3)" "unprognostic (2.96e-3)" "unprognostic (1.57e-1)" "unprognostic (5.11e-2)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "unprognostic (8.65e-3)" "unprognostic (7.74e-2)" "unprognostic (4.76e-2)" "unprognostic (2.62e-5)" "unprognostic (2.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.29e-2)" CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039487, HPA079296" Approved Approved "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 65: Breast cancer - Unknown function" "Cluster 64: Non-specific - Transcription" "Endoplasmic reticulum, Vesicles, Plasma membrane" "HPA039487: AB_10672776, HPA079296: " "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" CTBP1 BARS ENSG00000159692 "C-terminal binding protein 1" Q13363 4 1211445-1249953 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004217, HPA018987, HPA044971" Approved Enhanced Nucleoplasm NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "CAB004217: AB_627312, HPA018987: AB_1847307, HPA044971: AB_2679161" "unprognostic (6.19e-2)" "unprognostic (4.78e-2)" "unprognostic (9.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (3.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.52e-2)" "unprognostic (1.04e-2)" "unprognostic (9.65e-2)" "unprognostic (2.24e-2)" "unprognostic (6.35e-3)" "unprognostic (3.58e-2)" "unprognostic (3.36e-1)" "unprognostic (2.46e-2)" "unprognostic (3.00e-1)" "unprognostic (3.22e-2)" "prognostic favorable (8.94e-4)" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 367.9;Hofbauer cells: 149.1;Proximal enterocytes: 197.5" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cancer enhanced" "Detected in many" "liver cancer: 32.5;skin cancer: 61.9" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 19: Macrophages - Innate immune response" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 23 "Hepatocytes: 6502.1" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 13: Hepatocytes - Oxidoreductase activity" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 55.7;Late spermatids: 20.2;Prostatic glandular cells: 30.7;Serous glandular cells: 23.6" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 21: Serous glandular cells - Salivary secretion" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 59 "Hepatocytes: 2605.9;Proximal enterocytes: 1368.9" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 6: BEWO - Unknown function" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.2" "Cell type enhanced" "Detected in many" "Astrocytes: 56.3;Cone photoreceptor cells: 39.6;dendritic cells: 28.6;Excitatory neurons: 52.3;Inhibitory neurons: 40.7;Rod photoreceptor cells: 32.3" "Cancer enriched" "Detected in single" 5 "glioma: 1.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 38: Neurons - Neuronal signaling" "unprognostic (2.16e-1)" "unprognostic (4.30e-1)" "unprognostic (2.50e-5)" "unprognostic (9.48e-5)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (4.01e-2)" "unprognostic (1.32e-5)" "unprognostic (5.21e-2)" "unprognostic (2.44e-4)" "unprognostic (5.97e-4)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (3.88e-3)" CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "liver: 49.5" "Cell type enriched" "Detected in single" 16 "Hepatocytes: 6.8" "Cancer enriched" "Detected in single" 96 "liver cancer: 28.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-2)" "prognostic favorable (3.19e-4)" "unprognostic (7.60e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (8.43e-3)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Oligodendrocyte precursor cells: 90.5;Oligodendrocytes: 112.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Cancer enhanced" "Detected in some" "skin cancer: 2.8" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: Skin cancer - Membrane components" "Cluster 72: Smooth muscle cells - ECM organization" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 61 "Hepatocytes: 791.7" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 13: Hepatocytes - Oxidoreductase activity" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Group enriched" "Detected in some" 4 "Club cells: 147.8;Pancreatic endocrine cells: 80.7" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 270.9;Sarcoma: 255.9" "Skin - Sebaceous gland cells" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 73: Prostatic glandular cells - Transcription" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 56.9;placenta: 72.6" "Group enriched" "Detected in some" 20 "Cytotrophoblasts: 1130.7;Distal tubular cells: 422.9;Syncytiotrophoblasts: 1547.0" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gastric cancer: 17.8;liver cancer: 57.3" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 35: Liver cancer - Metabolism" "Cluster 28: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 280.2;Kupffer cells: 55.9;Proximal tubular cells: 126.7" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 29: Hepatocytes - Metabolism" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 15 "Horizontal cells: 130.1;Inhibitory neurons: 383.8;Oligodendrocyte precursor cells: 140.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 37: Neurons - Neuronal signaling" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216665-26304558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 37.6;retina: 9.5" "Group enriched" "Detected in some" 15 "Inhibitory neurons: 287.6;Pancreatic endocrine cells: 594.3" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "lung cancer: 1.3" "Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 32: Neurons - Synaptic function" "CAB078177: AB_2665779, HPA044637: AB_10794053" "unprognostic (8.67e-2)" "unprognostic (1.11e-1)" "unprognostic (4.93e-2)" "unprognostic (2.52e-5)" "unprognostic (5.44e-2)" "unprognostic (8.08e-2)" HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 56: Ciliated cells - Cilium assembly" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 141.8;Distal enterocytes: 585.7;Enteroendocrine cells: 135.1;Intestinal goblet cells: 249.2;Paneth cells: 276.6;Proximal enterocytes: 251.6;Syncytiotrophoblasts: 167.7" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 14.2;prostate cancer: 13.7" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Supported Vesicles NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 50: Enterocytes - Absorption" Vesicles "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 288.6;liver: 241.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 363.8;Distal enterocytes: 332.9;Paneth cells: 465.5;Proximal enterocytes: 1100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 768.7" "Group enriched" "Detected in all" 4 "granulocytes: 768.7;monocytes: 202.0" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 57: Non-specific - Translation" "Cluster 50: Enterocytes - Absorption" "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Hofbauer cells: 131.0;Proximal tubular cells: 372.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 60: Proximal tubular cells - Absorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 218.6;Hepatocytes: 238.4;Oligodendrocytes: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 57: Non-specific - Translation" "Cluster 70: Basal prostatic cells - Lipid metabolism" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 93.7;Proximal tubular cells: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 12: Non-specific - Chromatin organization" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 706.4" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 15.0;Gastric cancer: 19.5;testis cancer: 26.5" "Skin - Sebaceous gland cells" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 15 "Granulosa cells: 42.7;Proximal enterocytes: 52.4;Theca cells: 55.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "skin cancer: 10.8" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 38.9;Hepatocytes: 58.3;Hofbauer cells: 48.8;Proximal enterocytes: 45.5;Proximal tubular cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 267.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 61: Liver - Metabolism" "Cluster 50: Enterocytes - Absorption" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 289.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 48: Non-specific - RNA binding" "Cluster 16: Non-specific - RNA binding" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 72.9;Horizontal cells: 40.4;Melanocytes: 59.2;Schwann cells: 202.5;Sertoli cells: 38.7" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 25: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.7;fallopian tube: 22.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Early spermatids: 220.2;Endometrial ciliated cells: 43.0;Late spermatids: 37.0;Respiratory ciliated cells: 58.4;Spermatocytes: 95.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA073761 Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: Non-specific - Cilium assembly" "Cluster 56: Ciliated cells - Cilium assembly" "HPA073761: AB_2732241" "unprognostic (1.03e-2)" "unprognostic (9.44e-2)" "unprognostic (1.58e-1)" "unprognostic (9.84e-2)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (2.01e-1)" "unprognostic (3.66e-2)" "unprognostic (3.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (7.84e-3)" "unprognostic (3.01e-1)" MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Distal enterocytes: 116.2;Inhibitory neurons: 88.8;Proximal enterocytes: 179.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" PDZD4 "FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L" ENSG00000067840 "PDZ domain containing 4" Q76G19 X 153802166-153830565 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 150.1" "Cell type enhanced" "Detected in some" "Astrocytes: 11.7;Bipolar cells: 15.9;Excitatory neurons: 10.9;Horizontal cells: 17.3;NK-cells: 26.2;Rod photoreceptor cells: 12.5;Schwann cells: 9.8" "Group enriched" "Detected in many" 4 "glioma: 20.1;testis cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 44.7" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003878 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 7: NK-cells - Immune response regulation" "HPA003878: AB_2162807" "unprognostic (9.18e-3)" "unprognostic (1.25e-1)" "unprognostic (1.11e-4)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (1.85e-2)" "unprognostic (1.92e-3)" "unprognostic (2.17e-1)" "unprognostic (2.32e-3)" "unprognostic (5.90e-2)" "prognostic favorable (2.96e-5)" "unprognostic (2.27e-1)" "unprognostic (2.54e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.83e-2)" "unprognostic (2.87e-2)" PLXNB3 "PLEXB3, PLEXR, PLXN6" ENSG00000198753 "Plexin B3" Q9ULL4 X 153764196-153779346 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 210.2;intestine: 57.2" "Group enriched" "Detected in some" 5 "Astrocytes: 42.4;Oligodendrocytes: 68.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 57.3" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048046 Enhanced NA NA 390000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: Skin cancer - Membrane components" "Cluster 63: Astrocytes - Nervous system maintenance" "HPA048046: AB_2680239" "prognostic unfavorable (6.13e-4)" "unprognostic (2.60e-1)" "unprognostic (9.10e-4)" "unprognostic (2.30e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-3)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.66e-1)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (9.73e-3)" "unprognostic (1.98e-2)" PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 43.9;Cone photoreceptor cells: 31.0;Excitatory neurons: 28.6;Extravillous trophoblasts: 75.1;Granulosa cells: 48.2;Ionocytes: 45.2;Syncytiotrophoblasts: 61.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 13.7" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 173.3;Ionocytes: 213.5;Muller glia cells: 316.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 296.4;Rod photoreceptor cells: 453.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 41: Non-specific - Cilium assembly" "Cluster 44: Photoreceptor cells - Visual perception" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 5 "Syncytiotrophoblasts: 245.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 4: Non-specific - Transcription" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 46: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1116.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 1198.0;Proximal enterocytes: 777.0;Proximal tubular cells: 835.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 640000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 38: Non-specific - mRNA processing" "Cluster 13: Hepatocytes - Oxidoreductase activity" Peroxisomes Nucleoplasm "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favorable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favorable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 215.5;Alveolar cells type 2: 457.8;Basal respiratory cells: 335.5;Ionocytes: 292.4;Suprabasal keratinocytes: 237.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 5: Bronchus - Unknown function" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" SDR42E2 ENSG00000183921 "Short chain dehydrogenase/reductase family 42E, member 2" A6NKP2 16 22165583-22191754 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 3.2;choroid plexus: 1.8;fallopian tube: 2.1;pituitary gland: 1.2;testis: 2.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 28.1;Proximal enterocytes: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 4.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.9" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 64: Non-specific - Transcription" "unprognostic (8.03e-3)" "unprognostic (2.80e-1)" "unprognostic (2.06e-1)" "unprognostic (1.72e-4)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (8.77e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.32e-3)" "unprognostic (2.01e-1)" "unprognostic (7.09e-2)" "unprognostic (4.76e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (6.61e-2)" SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 29.7" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 3: Suprabasal keratinocytes - Cornification" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 262.1;Hepatocytes: 173.7;Proximal enterocytes: 79.5;Proximal tubular cells: 96.9;Respiratory ciliated cells: 71.9" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 1023.6" "Group enriched" "Detected in all" 5 "Early spermatids: 141.5;Hepatocytes: 342.9;Late spermatids: 462.8" "Cancer enriched" "Detected in all" 26 "liver cancer: 49.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007292, CAB056160, CAB068239" Enhanced NA NA "Cluster 30: Non-specific - Translation" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 51: Late spermatids - Spermatogenesis" "CAB056160: AB_2665590, CAB068239: AB_2665592, HPA007292: AB_1857064" "unprognostic (5.97e-2)" "unprognostic (9.12e-2)" "unprognostic (9.95e-2)" "unprognostic (6.36e-3)" "unprognostic (2.52e-1)" "unprognostic (7.46e-2)" "prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.66e-4)" "unprognostic (2.27e-1)" "unprognostic (3.33e-2)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 122.8;Cone photoreceptor cells: 127.5;Distal enterocytes: 139.7;Ionocytes: 120.0;Proximal enterocytes: 199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 50: Enterocytes - Absorption" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 211.4;tongue: 76.8" "Cell type enriched" "Detected in some" 7 "Skeletal myocytes: 141.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 27: Skeletal myocytes - Muscle contraction" "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" SSR4 TRAPD ENSG00000180879 "Signal sequence receptor subunit 4" P51571 X 153793516-153798499 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 3119.7" "Group enriched" "Detected in all" 4 "Late spermatids: 1769.3;Plasma cells: 5331.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045209 Enhanced Supported "Endoplasmic reticulum" NA NA 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA045209: AB_10961407" "unprognostic (3.56e-2)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" "prognostic favorable (1.76e-4)" "unprognostic (8.74e-2)" "unprognostic (5.57e-2)" "unprognostic (7.99e-2)" "unprognostic (4.58e-2)" "unprognostic (2.10e-1)" "unprognostic (5.04e-3)" "unprognostic (5.74e-3)" "unprognostic (8.76e-2)" "prognostic unfavorable (5.51e-6)" "unprognostic (8.18e-2)" "unprognostic (2.24e-1)" "unprognostic (6.01e-2)" "unprognostic (5.33e-2)" STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7147237-7804358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.1;Excitatory neurons: 31.7;Inhibitory neurons: 38.5;Syncytiotrophoblasts: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 28: Cytotrophoblasts - Unknown function" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1072.1" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 1791.1" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Cancer enriched" "Detected in some" 8 "liver cancer: 9.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 1200000 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enhanced" "Detected in some" "Club cells: 1.1;Collecting duct cells: 2.0;Proximal tubular cells: 5.0" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lung cancer: 1.2;Myeloma: 1.4" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: Non-specific - Cilium assembly" "Cluster 60: Proximal tubular cells - Absorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 31.4;kidney: 21.0;liver: 13.3;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 90.5;Distal enterocytes: 98.9;Enteroendocrine cells: 46.1;Hepatocytes: 51.7;Paneth cells: 58.7;Proximal enterocytes: 233.0;Proximal tubular cells: 114.4;Undifferentiated cells: 82.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045108 Supported NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: Liver cancer - Metabolism" "Cluster 59: Proximal enterocytes - Transmembrane transport" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 816.6" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "liver cancer: 31.5" "Liver - Hepatocytes" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 61: Liver - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 124.1;Endometrial ciliated cells: 128.4;Glandular and luminal cells: 230.1;Hepatocytes: 515.3;Proximal tubular cells: 965.4" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 88.8;Uterine cancer: 39.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 68: Kidney - Mixed function" "Cluster 60: Proximal tubular cells - Absorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099430-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 14 "Astrocytes: 899.0;Excitatory neurons: 266.4;Inhibitory neurons: 528.7;Microglial cells: 458.8;Oligodendrocyte precursor cells: 876.1;Oligodendrocytes: 749.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Golgi apparatus" Cytosol "HPA050992: AB_2681299" "prognostic unfavorable (9.07e-5)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-2)" "unprognostic (2.32e-1)" "unprognostic (1.81e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (4.33e-2)" "unprognostic (3.50e-2)" "prognostic favorable (4.49e-5)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.77e-1)"