Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
DHCR24	"DCE, KIAA0018, seladin-1"	ENSG00000116133	"24-dehydrocholesterol reductase"	Q15392	1	54849627-54887195	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 1129.5;liver: 623.5"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 342.3;Alveolar cells type 2: 502.0;Hepatocytes: 834.8;Kupffer cells: 367.5;Suprabasal keratinocytes: 289.8;Theca cells: 296.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Leydig cells"	"Low region specificity"	"Detected in all"							"HPA017981, CAB037247, HPA063005"	Enhanced					NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 68: Kidney - Mixed function"	"Cluster 29: Hepatocytes - Metabolism"			"CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919"	"unprognostic (2.88e-1)"	"unprognostic (1.80e-2)"	"unprognostic (4.99e-3)"	"prognostic unfavorable (1.05e-5)"	"unprognostic (1.69e-1)"	"unprognostic (2.61e-1)"	"unprognostic (1.54e-2)"	"unprognostic (1.85e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.86e-1)"	"unprognostic (6.18e-3)"	"unprognostic (3.35e-1)"	"unprognostic (7.82e-3)"	"unprognostic (5.48e-2)"	"unprognostic (1.83e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.97e-2)"
DHCR7	SLOS	ENSG00000172893	"7-dehydrocholesterol reductase"	Q9UBM7	11	71428193-71452868	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 161.1"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 102.9;Basal respiratory cells: 77.6;Granulosa cells: 78.1;Hepatocytes: 130.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044280	Approved		Supported	"Endoplasmic reticulum"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 39: Non-specific - Unknown function"	"Cluster 29: Hepatocytes - Metabolism"	"Endoplasmic reticulum"		"HPA044280: AB_10794893"	"unprognostic (1.76e-1)"	"unprognostic (1.50e-3)"	"unprognostic (1.32e-2)"	"unprognostic (7.16e-3)"	"unprognostic (2.69e-1)"	"unprognostic (2.18e-3)"	"unprognostic (8.57e-3)"	"unprognostic (3.02e-2)"	"unprognostic (4.91e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.08e-2)"	"unprognostic (5.45e-2)"	"prognostic favorable (6.93e-7)"	"unprognostic (1.73e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.15e-2)"	"prognostic unfavorable (5.67e-4)"
SC5D	SC5DL	ENSG00000109929	Sterol-C5-desaturase	O75845	11	121292681-121313410	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 393.6"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 300.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA066283, HPA070248"	Enhanced		Approved	"Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol"		No	No			"Cluster 44: Non-specific - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 39: Non-specific - Unknown function"	"Cluster 29: Hepatocytes - Metabolism"	"Nucleoplasm, Endoplasmic reticulum"	"Plasma membrane, Cytosol"	"HPA066283: AB_2685648, HPA070248: AB_2686240"	"unprognostic (4.78e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.26e-2)"	"unprognostic (2.36e-1)"	"unprognostic (3.98e-2)"	"prognostic unfavorable (3.30e-4)"	"unprognostic (2.79e-2)"	"unprognostic (7.96e-2)"	"prognostic unfavorable (3.98e-4)"	"unprognostic (4.03e-2)"	"unprognostic (3.18e-2)"	"unprognostic (1.01e-1)"	"prognostic favorable (1.07e-7)"	"unprognostic (4.29e-2)"	"unprognostic (2.51e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.98e-1)"
