Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ADPRH	ARH1	ENSG00000144843	"ADP-ribosylarginine hydrolase"	P54922	3	119579268-119589945	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"granulocytes: 15.8;Macrophages: 16.5;Syncytiotrophoblasts: 14.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"lymphoma: 12.8"	"Breast - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001701, HPA036961"	Approved		Approved	"Nucleoplasm,Nuclear membrane"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 9: Lymphoid cancers - Immune response"	"Cluster 75: Myeloid cells - Innate immune response"	"Nuclear membrane"	Nucleoplasm	"CAB001701: , HPA036961: AB_2675405"	"prognostic favorable (2.42e-4)"	"unprognostic (2.29e-1)"	"unprognostic (4.77e-1)"	"unprognostic (2.39e-2)"	"unprognostic (3.38e-2)"	"unprognostic (2.65e-1)"	"unprognostic (3.06e-2)"	"unprognostic (2.63e-1)"	"unprognostic (4.24e-2)"	"unprognostic (3.31e-3)"	"unprognostic (1.88e-1)"	"unprognostic (1.71e-1)"	"unprognostic (6.04e-2)"	"unprognostic (2.60e-3)"	"unprognostic (8.87e-2)"	"unprognostic (2.03e-1)"	"unprognostic (4.35e-2)"
PADI1	"HPAD10, PAD1, PDI, PDI1"	ENSG00000142623	"Peptidyl arginine deiminase 1"	Q9ULC6	1	17205128-17246007	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	6	"esophagus: 109.5"	"Group enriched"	"Detected in some"	4	"Club cells: 5.2;Extravillous trophoblasts: 16.9;Ionocytes: 4.9;Squamous epithelial cells: 6.4"	"Cancer enhanced"	"Detected in many"		"pancreatic cancer: 13.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"Bile duct cancer: 14.3;colorectal cancer: 5.4;Gallbladder cancer: 18.8;ovarian cancer: 10.7;pancreatic cancer: 14.0"	"Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA062294	Enhanced		Approved	Nucleoplasm,Cytosol		NA	NA				"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 54: Extravillous trophoblasts - Unknown function"	Cytosol	Nucleoplasm	"HPA062294: AB_2684741"	"unprognostic (9.30e-2)"	"unprognostic (2.44e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.40e-1)"	"unprognostic (5.22e-2)"	"unprognostic (7.27e-2)"	"unprognostic (3.84e-1)"	"unprognostic (3.37e-2)"	"unprognostic (1.41e-1)"	"unprognostic (7.75e-2)"	"unprognostic (1.01e-3)"	"unprognostic (3.64e-2)"	"prognostic unfavorable (8.34e-11)"	"unprognostic (2.00e-1)"	"unprognostic (3.12e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.15e-1)"
PADI2	"KIAA0994, PDI2"	ENSG00000117115	"Peptidyl arginine deiminase 2"	Q9Y2J8	1	17066761-17119451	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 240.6;skeletal muscle: 311.8;tongue: 492.3"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 63.8;Distal enterocytes: 177.3;Intestinal goblet cells: 75.6;Oligodendrocytes: 110.5;Paneth cells: 71.8;Schwann cells: 58.8;Skeletal myocytes: 61.4"	"Cancer enhanced"	"Detected in many"		"glioma: 24.7"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"eosinophil: 43.3;neutrophil: 100.6"	"Lineage enriched"	"Detected in many"	6	"granulocytes: 100.6"	"Cancer enhanced"	"Detected in many"		"breast cancer: 38.6"	"Colon - Colon enterocytes, Heart muscle - Neutrophils, Kidney - Ascending Loop of Henle cells, Liver - Neutrophils, Skin - Eccrine sweat gland cells, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047735	Enhanced					NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 50: Enterocytes - Absorption"			"HPA047735: AB_2680139"	"unprognostic (2.61e-2)"	"unprognostic (3.60e-2)"	"unprognostic (8.94e-3)"	"unprognostic (1.57e-1)"	"unprognostic (2.33e-2)"	"unprognostic (2.44e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.74e-3)"	"unprognostic (2.78e-3)"	"unprognostic (3.28e-3)"	"unprognostic (1.29e-1)"	"unprognostic (3.07e-1)"	"unprognostic (2.87e-1)"	"unprognostic (3.64e-2)"	"unprognostic (3.15e-1)"	"unprognostic (2.27e-1)"	"unprognostic (5.91e-3)"
PADI3	PDI3	ENSG00000142619	"Peptidyl arginine deiminase 3"	Q9ULW8	1	17249098-17284233	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	6	"esophagus: 17.0;urinary bladder: 25.6"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 6.6;Club cells: 6.1;Collecting duct cells: 2.0;Ionocytes: 1.1;Pancreatic endocrine cells: 1.7"	"Cancer enriched"	"Detected in many"	4	"urothelial cancer: 48.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"head and neck cancer: 20.6;Kidney cancer: 21.2"	"Prostate - Urothelial cells"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA043739			Supported	Nucleoplasm,Vesicles,Cytosol		NA	NA				"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 70: Basal prostatic cells - Lipid metabolism"	"Vesicles, Cytosol"	Nucleoplasm	"HPA043739: AB_10959466"	"unprognostic (4.47e-2)"	"unprognostic (9.32e-2)"	"unprognostic (1.50e-1)"	"prognostic unfavorable (3.22e-4)"	"unprognostic (1.05e-3)"	"unprognostic (6.66e-2)"	"unprognostic (3.10e-3)"	"unprognostic (5.88e-2)"	"unprognostic (2.06e-4)"	"unprognostic (1.03e-1)"	"unprognostic (3.47e-4)"	"unprognostic (1.76e-1)"	"prognostic unfavorable (1.55e-11)"	"unprognostic (2.40e-2)"	"unprognostic (4.73e-3)"		"unprognostic (2.64e-2)"
PADI4	"PAD, PADI5, PDI4, PDI5"	ENSG00000159339	"Peptidyl arginine deiminase 4"	Q9UM07	1	17308195-17364004	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Immunity, Innate immunity, Transcription, Transcription regulation"	"Chromatin regulator, Hydrolase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	9	"bone marrow: 105.1;lymphoid tissue: 29.9"	"Cell type enhanced"	"Detected in some"		"dendritic cells: 14.8;granulocytes: 5.6;Hofbauer cells: 8.0;Kupffer cells: 5.3;Macrophages: 8.8;monocytes: 16.0;NK-cells: 8.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	8	"basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0"	"Group enriched"	"Detected in all"	9	"granulocytes: 183.0;monocytes: 71.3"	"Cancer enriched"	"Detected in single"	11	"Leukemia: 3.3"	"Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Sebaceous gland cells, Stomach - Neutrophils, Thyroid - Neutrophils"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA017007, HPA042825"	Enhanced					NA	NA		29000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 33: Macrophages - Degranulation"			"HPA017007: AB_1854921, HPA042825: AB_2678189"	"unprognostic (1.70e-1)"	"unprognostic (2.25e-1)"	"unprognostic (2.23e-1)"	"unprognostic (2.98e-1)"	"unprognostic (1.27e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.47e-1)"	"unprognostic (4.91e-2)"	"unprognostic (8.49e-2)"	"unprognostic (5.22e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.66e-3)"	"unprognostic (1.50e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.56e-2)"	"unprognostic (1.80e-1)"
PADI6		ENSG00000276747	"Peptidyl arginine deiminase 6"	Q6TGC4	1	17372196-17401699	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Hydrolase	"Disease variant"	"Evidence at protein level"	"No human protein/transcript evidence"	"Evidence at protein level"	"Evidence at protein level"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"				"Region enhanced"	"Detected in single"		"white matter: 2.4"	"Not detected"	"Not detected"									NA	NA			"Cluster 28: Myeloid DCs - Unknown function"		"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"				"unprognostic (1.19e-1)"					"unprognostic (4.36e-2)"			"unprognostic (3.02e-2)"				"unprognostic (6.56e-2)"		"unprognostic (1.23e-1)"		
TPST1	TANGO13A	ENSG00000169902	"Tyrosylprotein sulfotransferase 1"	O60507	7	66205317-66420543	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Transferase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 76.1;Excitatory neurons: 100.4;Inhibitory neurons: 104.7;Spermatocytes: 99.2"	"Cancer enhanced"	"Detected in all"		"glioma: 36.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 52.2;neutrophil: 35.2"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA047415, HPA061837"	Approved		Supported	"Golgi apparatus"	"Intracellular and membrane"	NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 52: Endometrial stromal cells - ECM organization"	"Golgi apparatus"		"HPA047415: AB_10964056, HPA061837: AB_2732672"	"unprognostic (7.46e-2)"	"unprognostic (1.45e-1)"	"unprognostic (8.62e-2)"	"unprognostic (3.43e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.78e-3)"	"unprognostic (5.71e-2)"	"unprognostic (8.21e-2)"	"unprognostic (3.59e-1)"	"unprognostic (9.25e-3)"	"unprognostic (4.12e-2)"	"unprognostic (4.98e-1)"	"prognostic unfavorable (8.16e-6)"	"prognostic unfavorable (8.78e-4)"	"unprognostic (2.48e-1)"	"unprognostic (1.74e-2)"	"prognostic unfavorable (3.73e-5)"
TPST2	TANGO13B	ENSG00000128294	"Tyrosylprotein sulfotransferase 2"	O60704	22	26521996-26596717	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Transferase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"pancreas: 398.8"	"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 168.2;granulocytes: 134.8;NK-cells: 175.8;Plasma cells: 160.0;Syncytiotrophoblasts: 140.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA021054	Enhanced				"Intracellular and membrane"	NA	NA		88000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 25: Pancreas - Digestion"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 7: NK-cells - Immune response regulation"			"HPA021054: AB_1858221"	"unprognostic (2.24e-1)"	"unprognostic (1.70e-1)"	"unprognostic (1.74e-2)"	"prognostic favorable (8.08e-5)"	"unprognostic (8.88e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.19e-2)"	"unprognostic (9.70e-2)"	"unprognostic (3.18e-2)"	"unprognostic (3.38e-1)"	"unprognostic (2.70e-1)"	"unprognostic (5.54e-2)"	"prognostic unfavorable (2.34e-6)"	"unprognostic (9.68e-2)"	"unprognostic (9.21e-3)"	"unprognostic (5.62e-2)"	"unprognostic (2.01e-1)"
