Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ADCK1	FLJ39600	ENSG00000063761	"AarF domain containing kinase 1"	Q86TW2	14	77800109-77935014	"Enzymes, Predicted secreted proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocytes: 27.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA051012, HPA055014"	Uncertain		Uncertain	Nucleoplasm	"Secreted - unknown location"	NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 35: Non-specific - Unknown function"	"Cluster 46: Non-specific - Unknown function"	"Cluster 8: Oligodendrocytes - Myelin sheath organization"	Nucleoplasm		"HPA051012: AB_2681310, HPA055014: AB_2682672"	"unprognostic (6.36e-2)"	"unprognostic (7.09e-2)"	"unprognostic (6.00e-2)"	"unprognostic (1.76e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.46e-1)"	"prognostic unfavorable (1.70e-4)"	"prognostic favorable (4.11e-5)"	"unprognostic (2.33e-1)"	"unprognostic (1.64e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.38e-1)"	"prognostic favorable (5.82e-6)"	"unprognostic (6.30e-3)"	"unprognostic (2.06e-1)"	"unprognostic (9.57e-2)"	"unprognostic (4.06e-1)"
ADCK2	MGC20727	ENSG00000133597	"AarF domain containing kinase 2"	Q7Z695	7	140672945-140696261	"Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 95.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA036036	Approved		Uncertain	Centrosome,Cytosol		NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 31: Non-specific - Transcription"	"Cluster 17: Granulosa cells - Transcription regulation"	"Centrosome, Cytosol"		"HPA036036: AB_10672078"	"unprognostic (2.76e-1)"	"unprognostic (1.79e-1)"	"unprognostic (5.72e-2)"	"unprognostic (5.30e-2)"	"unprognostic (4.03e-3)"	"unprognostic (1.52e-1)"	"unprognostic (3.05e-2)"	"unprognostic (7.48e-2)"	"unprognostic (2.61e-1)"	"unprognostic (7.10e-3)"	"unprognostic (6.81e-3)"	"unprognostic (9.36e-3)"	"prognostic favorable (9.75e-5)"	"unprognostic (1.89e-2)"	"unprognostic (2.00e-1)"	"unprognostic (4.13e-1)"	"unprognostic (2.13e-1)"
ADCK5	FLJ35454	ENSG00000173137	"AarF domain containing kinase 5"	Q3MIX3	8	144373101-144393242	"Enzymes, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Proximal enterocytes: 56.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA025692, HPA028679"	Approved		Approved	"Plasma membrane,Cytosol"		NA	NA			"Cluster 24: B-cells - Unknown function"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 17: RS4;11 - Unknown function"	"Cluster 59: Proximal enterocytes - Transmembrane transport"	"Plasma membrane, Cytosol"		"HPA025692: AB_10599486, HPA028679: AB_10600226"	"unprognostic (6.76e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.68e-2)"	"unprognostic (8.96e-2)"	"unprognostic (1.68e-2)"	"unprognostic (1.00e-1)"	"unprognostic (2.31e-3)"	"unprognostic (6.45e-2)"	"unprognostic (2.70e-1)"	"unprognostic (4.25e-2)"	"unprognostic (6.60e-2)"	"unprognostic (2.03e-2)"	"unprognostic (1.33e-3)"	"unprognostic (1.39e-2)"	"unprognostic (1.20e-1)"	"unprognostic (3.47e-1)"	"unprognostic (2.90e-2)"
ALPK1	"FLJ22670, KIAA1527, Lak"	ENSG00000073331	"Alpha kinase 1"	Q96QP1	4	112285509-112442621	"Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cilium biogenesis/degradation, Immunity, Innate immunity"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 71.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 18.7"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"				"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in many"			"HPA027435, HPA027443"	Approved		Approved	Centrosome		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 54: Lymphoma - Cytokine signaling"	"Cluster 33: Macrophages - Degranulation"	Centrosome		"HPA027435: AB_10599614, HPA027443: AB_10599421"	"unprognostic (6.24e-2)"	"unprognostic (1.92e-1)"	"unprognostic (9.30e-2)"	"unprognostic (1.69e-2)"	"unprognostic (7.40e-2)"	"unprognostic (5.45e-2)"	"unprognostic (2.55e-2)"	"unprognostic (7.47e-2)"	"unprognostic (2.34e-1)"	"unprognostic (1.38e-1)"	"unprognostic (7.14e-2)"	"unprognostic (2.78e-1)"	"prognostic unfavorable (5.82e-7)"	"unprognostic (1.60e-1)"	"unprognostic (4.17e-2)"	"unprognostic (2.81e-1)"	"prognostic favorable (1.17e-4)"
ALPK2	HAK	ENSG00000198796	"Alpha kinase 2"	Q86TB3	18	58481247-58629091	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2"	"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 137.8;Cone photoreceptor cells: 39.6;Late spermatids: 24.0;Skeletal myocytes: 59.4"	"Cancer enriched"	"Detected in some"	6	"renal cancer: 7.3"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Kidney cancer: 36.7"	"Heart muscle - Cardiomyocytes, Testis - Late spermatids"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA027377, HPA027976, HPA028084, HPA029801"	Uncertain		Approved	Cytosol		NA	NA				"Cluster 38: Heart - Muscle contraction"	"Cluster 68: Kidney - Mixed function"	"Cluster 77: Cardiomyocytes - Muscle contraction"	Cytosol		"HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006"	"unprognostic (7.35e-2)"	"unprognostic (4.91e-2)"	"unprognostic (1.64e-1)"	"unprognostic (4.60e-3)"	"unprognostic (2.64e-1)"	"unprognostic (8.27e-2)"	"unprognostic (1.22e-1)"	"unprognostic (1.41e-1)"	"unprognostic (3.44e-1)"	"unprognostic (1.06e-1)"	"unprognostic (5.13e-2)"	"unprognostic (1.33e-2)"	"prognostic unfavorable (8.20e-5)"	"unprognostic (5.27e-3)"	"unprognostic (2.50e-1)"	"unprognostic (4.73e-2)"	"unprognostic (3.20e-2)"
ALPK3	"KIAA1330, MAK, Midori"	ENSG00000136383	"Alpha kinase 3"	Q96L96	15	84817356-84873479	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		"Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase"	"Cardiomyopathy, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"heart muscle: 62.7;skeletal muscle: 195.8;tongue: 59.1"	"Group enriched"	"Detected in many"	5	"Cardiomyocytes: 54.0;Skeletal myocytes: 200.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Sarcoma: 10.0"	"Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			HPA026558	Uncertain		Approved	Nucleoplasm		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 27: Skeletal myocytes - Muscle contraction"	Nucleoplasm		"HPA026558: AB_1844774"	"unprognostic (2.69e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.71e-2)"	"unprognostic (4.61e-2)"	"unprognostic (2.08e-1)"	"unprognostic (6.53e-2)"	"unprognostic (1.44e-3)"	"unprognostic (1.42e-1)"	"unprognostic (1.68e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.74e-3)"	"unprognostic (1.23e-1)"	"prognostic favorable (3.95e-7)"	"unprognostic (1.76e-2)"	"unprognostic (1.77e-1)"	"unprognostic (2.96e-2)"	"unprognostic (4.87e-2)"
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222832-108369102	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 275.2;Oligodendrocytes: 205.4;Rod photoreceptor cells: 228.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Vesicles	"CAB000102: , HPA067142: AB_2685789"	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"
ATR	"FRP1, MEC1, SCKL, SCKL1"	ENSG00000175054	"ATR serine/threonine kinase"	Q13535	3	142449007-142578733	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins"	"DNA damage, DNA repair"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Dwarfism, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054320			Supported	"Nucleoplasm,Golgi apparatus"		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 43: Non-specific - Mitochondria"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	"Golgi apparatus"	"HPA054320: AB_2682448"	"unprognostic (1.47e-1)"	"unprognostic (8.90e-2)"	"unprognostic (2.90e-1)"	"unprognostic (4.23e-2)"	"unprognostic (2.25e-2)"	"unprognostic (6.42e-2)"	"prognostic unfavorable (8.39e-5)"	"unprognostic (3.44e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.02e-1)"	"prognostic unfavorable (1.23e-5)"	"unprognostic (1.94e-1)"	"unprognostic (5.61e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.55e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.43e-1)"
BCKDK		ENSG00000103507	"Branched chain keto acid dehydrogenase kinase"	O14874	16	31106107-31112791	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase"	"Autism, Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0"	"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017995, HPA056067"	Supported		Supported	Mitochondria		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 8: Non-specific - Transcription"	"Cluster 40: Plasma cells - Humoral immune response"	Mitochondria		"HPA017995: AB_1845309, HPA056067: AB_2683024"	"unprognostic (1.37e-1)"	"unprognostic (2.57e-1)"	"unprognostic (6.94e-2)"	"unprognostic (5.20e-2)"	"unprognostic (5.39e-2)"	"unprognostic (3.61e-2)"	"unprognostic (1.01e-1)"	"unprognostic (5.47e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.35e-1)"	"unprognostic (3.24e-2)"	"unprognostic (2.66e-3)"	"unprognostic (4.85e-2)"	"unprognostic (3.93e-2)"	"unprognostic (1.00e-1)"	"unprognostic (4.97e-2)"
COQ8A	"ADCK3, CABC1, COQ8, SCAR9"	ENSG00000163050	"Coenzyme Q8A"	Q8NI60	1	226940286-226987544	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Ubiquinone biosynthesis"	"Kinase, Transferase"	"Disease variant, Neurodegeneration, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"skeletal muscle: 1165.1;tongue: 484.7"	"Cell type enhanced"	"Detected in some"		"Basal squamous epithelial cells: 13.4;Erythroid cells: 8.3;Excitatory neurons: 16.4;Gastric mucus-secreting cells: 17.9;Inhibitory neurons: 13.9;Oligodendrocytes: 13.3;Plasma cells: 10.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA061662			Supported	Mitochondria		NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 57: Non-specific - Translation"	"Cluster 61: Non-specific - Transcription"	Mitochondria		"HPA061662: AB_2684578"	"unprognostic (6.37e-3)"	"unprognostic (2.09e-2)"	"unprognostic (2.29e-1)"	"unprognostic (9.06e-2)"	"unprognostic (8.94e-2)"	"unprognostic (2.49e-1)"	"unprognostic (4.42e-2)"	"unprognostic (3.50e-3)"	"unprognostic (1.81e-1)"	"unprognostic (4.02e-1)"	"unprognostic (4.15e-3)"	"unprognostic (8.67e-2)"	"unprognostic (2.40e-2)"	"unprognostic (9.24e-2)"	"unprognostic (2.82e-1)"	"unprognostic (8.88e-2)"	"unprognostic (2.62e-1)"
COQ8B	"ADCK4, COQ8, FLJ12229"	ENSG00000123815	"Coenzyme Q8B"	Q96D53	19	40691514-40725784	"Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027229, HPA027277, HPA027279, HPA028303"	Supported		Enhanced	Mitochondria		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 4: Non-specific - Transcription"	"Cluster 56: Ciliated cells - Cilium assembly"	Mitochondria		"HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551"	"unprognostic (7.57e-2)"	"unprognostic (9.48e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.36e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.79e-1)"	"unprognostic (4.63e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.27e-1)"	"unprognostic (2.82e-2)"	"unprognostic (1.48e-1)"	"unprognostic (2.93e-2)"	"unprognostic (6.18e-2)"	"unprognostic (1.46e-1)"	"unprognostic (7.17e-2)"	"unprognostic (2.65e-2)"
EEF2K	"CaMKIII, eEF-2K"	ENSG00000103319	"Eukaryotic elongation factor 2 kinase"	O00418	16	22206278-22288738	"Enzymes, Predicted intracellular proteins"		"Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skin 1: 49.0"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 79.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB007818, HPA056061"	Approved		Approved	Nucleoplasm		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 31: Skin - Epidermis development"	"Cluster 46: Non-specific - Unknown function"	"Cluster 65: Fibroblasts - ECM organization"	Nucleoplasm		"CAB007818: AB_598150, HPA056061: AB_2683021"	"unprognostic (4.79e-2)"	"unprognostic (6.10e-1)"	"unprognostic (3.89e-2)"	"unprognostic (3.49e-1)"	"unprognostic (1.94e-2)"	"unprognostic (5.09e-3)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (1.74e-1)"	"unprognostic (8.50e-2)"	"unprognostic (2.01e-2)"	"unprognostic (9.07e-3)"	"prognostic unfavorable (2.38e-4)"	"unprognostic (2.86e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.24e-1)"	"unprognostic (1.80e-1)"
FASTK	FAST	ENSG00000164896	"Fas activated serine/threonine kinase"	Q14296	7	151076593-151080866	"Enzymes, Predicted intracellular proteins"	Apoptosis	"Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031621, CAB032539"	Approved		Supported	"Nuclear speckles,Mitochondria"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 31: Non-specific - Transcription"	"Cluster 16: Non-specific - RNA binding"	Mitochondria	"Nuclear speckles"	"CAB032539: AB_2101115, HPA031621: AB_10611966"	"unprognostic (7.67e-2)"	"unprognostic (6.41e-3)"	"prognostic unfavorable (4.73e-4)"	"unprognostic (2.60e-1)"	"unprognostic (1.75e-3)"	"unprognostic (2.03e-3)"	"unprognostic (1.14e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.24e-1)"	"unprognostic (4.66e-2)"	"prognostic favorable (3.99e-4)"	"unprognostic (3.49e-2)"	"unprognostic (2.79e-2)"	"unprognostic (4.12e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.09e-1)"	"unprognostic (8.17e-2)"
MTOR	"FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1"	ENSG00000198793	"Mechanistic target of rapamycin kinase"	P42345	1	11106535-11262551	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Biological rhythms"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB069425, CAB080053, CAB080065, CAB080070, CAB080081, CAB080095, CAB080096, CAB080097"	Supported		Supported	"Golgi apparatus,Cytosol"		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 12: Non-specific - Chromatin organization"	"Golgi apparatus, Cytosol"		"CAB069425: , CAB080053: , CAB080065: , CAB080070: , CAB080081: , CAB080095: , CAB080096: , CAB080097: "	"unprognostic (3.18e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.20e-1)"	"unprognostic (2.45e-3)"	"unprognostic (5.50e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.24e-3)"	"unprognostic (3.48e-2)"	"unprognostic (1.88e-1)"	"prognostic favorable (1.49e-5)"	"unprognostic (1.27e-1)"	"unprognostic (2.45e-1)"	"unprognostic (6.60e-2)"	"unprognostic (7.55e-2)"
PDK1		ENSG00000152256	"Pyruvate dehydrogenase kinase 1"	Q15118	2	172555373-172608669	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	"Kinase, Transferase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 135.0;Plasma cells: 141.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in all"	5	"B-cells: 8.6;granulocytes: 25.2;T-cells: 21.2"	"Cancer enhanced"	"Detected in all"		"Myeloma: 60.3"	"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017554, HPA027376"	Approved					NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 34: Plasma cells - Humoral immune response"			"CAB017554: AB_2161138, HPA027376: AB_1855139"	"unprognostic (2.14e-1)"	"prognostic unfavorable (7.30e-5)"	"unprognostic (1.21e-1)"	"unprognostic (3.94e-2)"	"unprognostic (6.47e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.02e-2)"	"unprognostic (1.45e-1)"	"unprognostic (9.69e-3)"	"unprognostic (6.44e-2)"	"unprognostic (5.44e-3)"	"unprognostic (1.55e-1)"	"prognostic unfavorable (1.10e-8)"	"unprognostic (1.82e-1)"	"unprognostic (1.94e-1)"	"unprognostic (2.56e-2)"	"unprognostic (5.34e-2)"
PDK2	PDHK2	ENSG00000005882	"Pyruvate dehydrogenase kinase 2"	Q15119	17	50094737-50112152	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 216.2;tongue: 285.0"	"Cell type enhanced"	"Detected in all"		"Proximal enterocytes: 117.5;Proximal tubular cells: 112.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008287	Supported		Approved	Nucleoplasm,Mitochondria		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 60: Proximal tubular cells - Absorption"	"Nucleoplasm, Mitochondria"		"HPA008287: AB_1079589"	"unprognostic (2.74e-2)"	"prognostic favorable (5.87e-4)"	"unprognostic (1.16e-1)"	"unprognostic (2.43e-3)"	"unprognostic (1.22e-1)"	"unprognostic (9.63e-3)"	"unprognostic (9.80e-3)"	"unprognostic (8.39e-3)"	"unprognostic (3.19e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.17e-2)"	"unprognostic (2.21e-1)"	"prognostic favorable (9.59e-5)"	"unprognostic (3.81e-1)"	"unprognostic (2.54e-1)"	"unprognostic (5.33e-1)"	"unprognostic (1.55e-1)"
PDK3		ENSG00000067992	"Pyruvate dehydrogenase kinase 3"	Q15120	X	24465270-24550466	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	"Kinase, Transferase"	"Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 91.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Smooth muscle cells, Skin - Eccrine sweat gland cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA046583, HPA072492"	Approved		Supported	Nucleoli,Mitochondria		NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 64: Lymphoma - Humoral immune response"	"Cluster 15: Smooth muscle cells - Muscle contraction"	Mitochondria	Nucleoli	"HPA046583: AB_2679707, HPA072492: AB_2686526"	"unprognostic (5.41e-3)"	"unprognostic (5.43e-3)"	"unprognostic (5.35e-3)"	"unprognostic (3.40e-1)"	"unprognostic (4.05e-3)"	"unprognostic (5.38e-2)"	"prognostic unfavorable (2.76e-4)"	"unprognostic (1.51e-1)"	"unprognostic (5.57e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.39e-2)"	"unprognostic (2.02e-1)"	"unprognostic (1.72e-1)"	"unprognostic (1.02e-1)"	"unprognostic (2.92e-1)"	"unprognostic (2.28e-2)"	"unprognostic (9.43e-3)"
PDK4		ENSG00000004799	"Pyruvate dehydrogenase kinase 4"	Q16654	7	95583499-95596516	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Carbohydrate metabolism, Glucose metabolism"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 2300.1;tongue: 1216.5"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 650.4;Basal prostatic cells: 2647.5;Cardiomyocytes: 798.2;Skeletal myocytes: 1642.0"	"Cancer enhanced"	"Detected in all"		"renal cancer: 107.8;thyroid cancer: 89.5"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	12	"classical monocyte: 32.5;eosinophil: 38.1;intermediate monocyte: 63.5;myeloid DC: 16.8;non-classical monocyte: 39.8"	"Group enriched"	"Detected in many"	12	"dendritic cells: 16.8;granulocytes: 38.1;monocytes: 63.5"	"Cancer enhanced"	"Detected in many"		"cervical cancer: 20.0"	"Liver - Hepatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056731	Approved					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 70: Basal prostatic cells - Lipid metabolism"			"HPA056731: AB_2683218"	"unprognostic (3.18e-3)"	"unprognostic (1.98e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.34e-1)"	"unprognostic (5.15e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.00e-3)"	"unprognostic (3.47e-1)"	"unprognostic (6.38e-2)"	"unprognostic (2.24e-3)"	"unprognostic (1.87e-2)"	"unprognostic (8.75e-2)"	"unprognostic (2.41e-2)"	"prognostic unfavorable (1.80e-4)"	"unprognostic (9.15e-2)"	"unprognostic (4.20e-2)"	"unprognostic (1.12e-1)"
PIK3C2A	PI3K-C2alpha	ENSG00000011405	"Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha"	O00443	11	17077730-17207983	"Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Endocytosis, Exocytosis, Lipid metabolism"	"Kinase, Transferase"	"Cataract, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 210.7;Syncytiotrophoblasts: 158.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skeletal muscle - Endothelial cells, Stomach - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037641, HPA037642"	Uncertain		Supported	Nucleoplasm,Vesicles,Cytosol		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 66: Endothelial cells - Angiogenesis"	Nucleoplasm	"Vesicles, Cytosol"	"HPA037641: AB_10671878, HPA037642: AB_10697081"	"unprognostic (2.35e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.63e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.47e-2)"	"unprognostic (1.39e-1)"	"unprognostic (2.29e-2)"	"unprognostic (1.86e-2)"	"unprognostic (4.74e-2)"	"unprognostic (1.84e-1)"	"prognostic favorable (1.66e-4)"	"unprognostic (3.20e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.18e-1)"	"unprognostic (1.37e-1)"
PIK3CA	PI3K	ENSG00000121879	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha"	P42336	3	179148114-179240093	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Angiogenesis, Lipid metabolism, Phagocytosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 124.9;Inhibitory neurons: 119.3;Oligodendrocyte precursor cells: 124.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA009985, CAB017804"	Approved		Approved	Mitochondria,Cytosol		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 43: Non-specific - Mitochondria"	"Cluster 15: Smooth muscle cells - Muscle contraction"	Cytosol	Mitochondria	"CAB017804: , HPA009985: AB_1079610"	"unprognostic (1.81e-1)"	"unprognostic (2.77e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.69e-3)"	"unprognostic (6.49e-3)"	"unprognostic (1.43e-1)"	"unprognostic (2.65e-2)"	"unprognostic (1.00e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.37e-1)"	"unprognostic (2.57e-3)"	"unprognostic (5.21e-2)"	"unprognostic (4.50e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.48e-1)"	"unprognostic (9.74e-2)"	"unprognostic (3.82e-2)"
PIK3CB	PIK3C1	ENSG00000051382	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta"	P42338	3	138652698-138834928	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Autophagy, Cell adhesion, Endocytosis, Lipid metabolism"	"Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 95.1;Inhibitory neurons: 90.3;Oligodendrocytes: 83.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB031938, HPA042288, HPA064207"	Approved		Supported	Nucleoplasm,Nucleoli,Midbody		Yes	No			"Cluster 52: Eosinophils - Transcription"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 54: Extravillous trophoblasts - Unknown function"	Nucleoplasm	"Nucleoli, Midbody"	"CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212"	"unprognostic (4.89e-2)"	"unprognostic (1.42e-2)"	"unprognostic (5.97e-2)"	"unprognostic (7.85e-2)"	"unprognostic (4.89e-2)"	"unprognostic (6.01e-2)"	"prognostic unfavorable (6.42e-4)"	"unprognostic (3.98e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.28e-1)"	"prognostic unfavorable (3.99e-5)"	"unprognostic (2.15e-1)"	"unprognostic (6.18e-3)"	"unprognostic (9.33e-2)"	"unprognostic (7.82e-2)"	"unprognostic (2.79e-1)"	"unprognostic (4.59e-2)"
PIK3CD	p110D	ENSG00000171608	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta"	O00329	1	9651731-9729114	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity, Lipid metabolism"	"Kinase, Transferase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 60.9;lymphoid tissue: 50.4"	"Cell type enhanced"	"Detected in many"		"B-cells: 24.2;dendritic cells: 34.7;Kupffer cells: 25.1;Macrophages: 24.1;Microglial cells: 28.3;monocytes: 22.0;NK-cells: 28.9;T-cells: 35.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in all"		"Leukemia: 58.7;lymphoma: 54.5"	"Prostate - T-cells, Testis - Spermatogonia, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015420, HPA044953"	Enhanced		Approved	"Vesicles,Cytokinetic bridge"		Yes	No			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 2: Immune cells - Immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 2: T-cells - T-cell receptor"	Vesicles	"Cytokinetic bridge"	"CAB015420: AB_831654, HPA044953: AB_2679153"	"unprognostic (5.73e-3)"	"unprognostic (2.75e-3)"	"unprognostic (8.93e-2)"	"unprognostic (4.05e-2)"	"unprognostic (4.71e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.13e-1)"	"unprognostic (7.42e-2)"	"unprognostic (2.78e-2)"	"unprognostic (1.54e-2)"	"unprognostic (3.46e-2)"	"unprognostic (6.75e-2)"	"unprognostic (8.65e-3)"	"unprognostic (2.09e-1)"	"unprognostic (1.34e-1)"	"unprognostic (2.04e-1)"	"unprognostic (6.78e-2)"
PIK3CG		ENSG00000105851	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma"	P48736	7	106865278-106908980	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"	"Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response, Lipid metabolism"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 43.6;lymphoid tissue: 19.7"	"Cell type enhanced"	"Detected in many"		"B-cells: 32.2;dendritic cells: 120.2;Macrophages: 35.3;monocytes: 68.0;NK-cells: 36.6;Plasma cells: 84.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in some"	14	"Leukemia: 18.1;lymphoma: 22.3;Myeloma: 19.9"	"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA069976	Enhanced		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 45: Plasma cells - Humoral immune response"	"Plasma membrane"	Cytosol	"HPA069976: AB_2686224"	"unprognostic (8.34e-2)"	"unprognostic (2.01e-2)"	"unprognostic (1.44e-2)"	"unprognostic (1.71e-2)"	"unprognostic (3.20e-2)"	"unprognostic (3.82e-3)"	"unprognostic (3.02e-1)"	"unprognostic (6.77e-2)"	"unprognostic (1.16e-1)"	"unprognostic (7.06e-3)"	"unprognostic (1.15e-1)"	"unprognostic (1.97e-1)"	"unprognostic (1.77e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.23e-1)"	"unprognostic (5.38e-1)"	"unprognostic (5.24e-2)"
PRKDC	"DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7"	ENSG00000253729	"Protein kinase, DNA-activated, catalytic subunit"	P78527	8	47773111-47960178	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005167, HPA035174"	Supported		Enhanced	Nucleoplasm		NA	NA		250000	"Cluster 6: Non-specific - Transcription"	"Cluster 59: Non-specific - Translation"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 16: Non-specific - RNA binding"	Nucleoplasm		"CAB005167: AB_2172845, HPA035174: AB_2674504"	"unprognostic (3.14e-2)"	"unprognostic (3.02e-3)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (1.03e-4)"	"unprognostic (8.95e-2)"	"unprognostic (1.34e-1)"	"unprognostic (7.70e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.60e-2)"	"unprognostic (7.76e-3)"	"unprognostic (7.77e-2)"	"unprognostic (2.84e-2)"	"unprognostic (2.32e-1)"	"unprognostic (2.20e-1)"	"unprognostic (6.76e-3)"	"unprognostic (2.15e-2)"
RIOK1	"AD034, bA288G3.1, FLJ30006, RRP10"	ENSG00000124784	"RIO kinase 1"	Q9BRS2	6	7389793-7418037	"Enzymes, Predicted intracellular proteins"	"Ribosome biogenesis"	"Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 97.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017866, HPA051446"	Enhanced		Supported	Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 15: Non-specific - Protein binding"	"Cluster 16: Non-specific - RNA binding"	Cytosol		"HPA017866: AB_2669670, HPA051446: AB_2681488"	"unprognostic (2.33e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.38e-1)"	"unprognostic (1.03e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.51e-1)"	"prognostic unfavorable (3.41e-5)"	"unprognostic (2.23e-1)"	"prognostic unfavorable (4.43e-4)"	"unprognostic (3.45e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.87e-1)"	"prognostic unfavorable (5.85e-5)"	"unprognostic (2.33e-1)"	"unprognostic (2.09e-1)"	"unprognostic (6.12e-3)"	"unprognostic (2.59e-2)"
RIOK2	FLJ11159	ENSG00000058729	"RIO kinase 2"	Q9BVS4	5	97160867-97183247	"Enzymes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Ribosome biogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005681	Uncertain		Approved	"Plasma membrane,Cytosol"		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 54: Non-specific - Microtubule organization"	"Cluster 57: Non-specific - Translation"	"Cluster 1: T-cells - Immune response"	Cytosol	"Plasma membrane"	"HPA005681: AB_1856286"	"unprognostic (6.36e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.13e-2)"	"unprognostic (8.04e-2)"	"unprognostic (1.38e-1)"	"unprognostic (4.51e-2)"	"unprognostic (2.71e-3)"	"unprognostic (3.08e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.76e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.26e-3)"	"unprognostic (3.60e-1)"	"unprognostic (9.98e-2)"	"unprognostic (1.43e-2)"	"unprognostic (1.39e-2)"
RIOK3	SUDD	ENSG00000101782	"RIO kinase 3"	O14730	18	23453287-23486603	"Enzymes, Predicted intracellular proteins"	"Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 174.3"	"Cell type enhanced"	"Detected in all"		"Late spermatids: 330.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001620, HPA024184"	Approved		Approved	"Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 14: Endometrium - Transcription regulation"	"Plasma membrane, Cytosol"	"Golgi apparatus, Centriolar satellite"	"HPA001620: AB_1079815, HPA024184: AB_1856289"	"unprognostic (7.99e-2)"	"unprognostic (1.71e-2)"	"unprognostic (2.39e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.05e-1)"	"unprognostic (7.48e-2)"	"unprognostic (8.98e-3)"	"unprognostic (1.01e-1)"	"unprognostic (5.10e-2)"	"unprognostic (4.20e-1)"	"prognostic unfavorable (4.10e-4)"	"prognostic unfavorable (5.80e-4)"	"unprognostic (3.90e-2)"	"unprognostic (1.46e-1)"	"unprognostic (5.44e-2)"	"unprognostic (1.39e-1)"	"unprognostic (2.71e-2)"
SMG1	"ATX, KIAA0421, LIP"	ENSG00000157106	"SMG1 nonsense mediated mRNA decay associated PI3K related kinase"	Q96Q15	16	18804860-18926408	"Enzymes, Predicted intracellular proteins"	"DNA damage, DNA repair, Nonsense-mediated mRNA decay"	"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Skeletal myocytes: 276.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 31.7"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 31.7"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006870, HPA031623, HPA073972"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 42: Non-specific - Transcription"	"Cluster 50: Non-specific - Ribosome"	"Cluster 8: Non-specific - Transcription"	"Cluster 48: Plasmacytoid dendritic cells - Unknown function"	Nucleoplasm		"HPA006870: AB_1079725, HPA031623: AB_2673962, HPA073972: AB_2686648"	"unprognostic (6.34e-2)"	"unprognostic (5.88e-2)"	"unprognostic (5.98e-2)"	"unprognostic (2.66e-1)"	"unprognostic (2.44e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.28e-1)"	"unprognostic (1.22e-1)"	"unprognostic (2.42e-1)"	"unprognostic (8.32e-3)"	"unprognostic (7.28e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.61e-2)"	"unprognostic (1.15e-1)"	"unprognostic (3.17e-2)"	"unprognostic (2.45e-2)"
TRPM6	"CHAK2, FLJ22628, HOMG, HSH"	ENSG00000119121	"Transient receptor potential cation channel subfamily M member 6"	Q9BX84	9	74722495-74888094	"Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Calcium transport, Ion transport, Transport"	"Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase"	"Disease variant, Primary hypomagnesemia"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"brain: 6.6;intestine: 16.6"	"Group enriched"	"Detected in some"	6	"Distal enterocytes: 66.3;Glandular and luminal cells: 28.2;Microglial cells: 38.3;Oligodendrocytes: 76.5;Proximal enterocytes: 19.6"	"Cancer enhanced"	"Detected in some"		"testis cancer: 1.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	6	"basophil: 23.1;neutrophil: 7.5"	"Lineage enriched"	"Detected in single"	41	"granulocytes: 23.1"	"Cancer enhanced"	"Detected in some"		"Gallbladder cancer: 2.8"	"Kidney - Intercalated cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 45: Intestine - Brush border"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 50: Enterocytes - Absorption"				"unprognostic (3.95e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.76e-1)"	"unprognostic (1.65e-1)"	"unprognostic (7.80e-2)"	"unprognostic (9.20e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.72e-1)"	"unprognostic (2.82e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.72e-4)"	"unprognostic (1.58e-1)"	"unprognostic (1.71e-2)"	"unprognostic (8.10e-2)"	"unprognostic (7.54e-2)"	"unprognostic (1.89e-2)"	"unprognostic (2.11e-2)"
TRPM7	"CHAK1, LTRPC7, TRP-PLIK"	ENSG00000092439	"Transient receptor potential cation channel subfamily M member 7"	Q96QT4	15	50552473-50686797	"Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Calcium transport, Ion transport, Necrosis, Transport"	"Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase"	"Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"parathyroid gland: 108.9"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 120.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035522, HPA052173"	Enhanced		Approved	"Vesicles,Plasma membrane,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 12: Non-specific - Chromatin organization"	"Plasma membrane"	"Vesicles, Cytosol"	"HPA035522: , HPA052173: AB_2681749"	"unprognostic (3.14e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.58e-1)"	"unprognostic (1.42e-2)"	"unprognostic (1.89e-1)"	"unprognostic (1.60e-2)"	"unprognostic (1.85e-2)"	"unprognostic (2.59e-2)"	"unprognostic (5.46e-3)"	"unprognostic (2.64e-1)"	"unprognostic (2.91e-1)"	"unprognostic (1.59e-2)"	"unprognostic (3.20e-2)"	"unprognostic (2.08e-1)"	"unprognostic (7.59e-2)"	"unprognostic (9.45e-2)"	"unprognostic (1.97e-1)"