Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
AMER1	"FAM123B, FLJ39827, RP11-403E24.2, WTX"	ENSG00000184675	"APC membrane recruitment protein 1"	Q5JTC6	X	64185117-64205708	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"tongue: 15.3"	"Cell type enhanced"	"Detected in many"		"Theca cells: 6.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065214, HPA065265"	Approved		Supported	"Nuclear bodies,Vesicles,Plasma membrane"		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 48: Non-specific - RNA binding"	"Cluster 16: Non-specific - RNA binding"	"Nuclear bodies"	"Vesicles, Plasma membrane"	"HPA065214: AB_2685435, HPA065265: AB_2685450"	"unprognostic (1.56e-2)"	"unprognostic (8.85e-2)"	"unprognostic (6.86e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.75e-1)"	"unprognostic (6.31e-2)"	"unprognostic (3.43e-1)"	"unprognostic (4.69e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.19e-2)"	"unprognostic (2.89e-1)"
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC regulator of WNT signaling pathway"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 52.8"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 519.7;Inhibitory neurons: 231.0;Oligodendrocyte precursor cells: 188.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013349, HPA013362"	Supported		Supported	"Golgi apparatus,Plasma membrane"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 57: Non-specific - Translation"	"Cluster 63: Astrocytes - Nervous system maintenance"	"Plasma membrane"	"Golgi apparatus"	"HPA013349: AB_1844913, HPA013362: "	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"
APOBEC3B	"FLJ21201, PHRBNL"	ENSG00000179750	"Apolipoprotein B mRNA editing enzyme catalytic subunit 3B"	Q9UH17	22	38982347-38992804	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Antiviral defense, Immunity, Innate immunity"	"Hydrolase, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 28.4;intestine: 12.1"	"Cell type enhanced"	"Detected in some"		"Ductal cells: 10.9;Erythroid cells: 8.7;Pancreatic endocrine cells: 8.6;Plasma cells: 24.0"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in many"		"memory B-cell: 7.2"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung)"									"HPA056980, HPA066719"			Approved	Nucleoplasm		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 40: Plasma cells - Humoral immune response"	Nucleoplasm		"HPA056980: AB_2683298, HPA066719: AB_2685711"	"unprognostic (2.92e-2)"	"prognostic favorable (2.58e-5)"	"unprognostic (4.29e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.35e-1)"	"unprognostic (6.36e-2)"	"unprognostic (1.08e-2)"	"unprognostic (5.88e-2)"	"prognostic unfavorable (2.78e-4)"	"unprognostic (8.47e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.70e-1)"	"unprognostic (1.04e-1)"
ARID1A	"B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1"	ENSG00000117713	"AT-rich interaction domain 1A"	O14497	1	26693236-26782104	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005456, CAB016334"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"CAB016334: AB_673396, HPA005456: AB_1078205"	"unprognostic (2.83e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.89e-2)"	"prognostic unfavorable (4.18e-4)"	"unprognostic (3.02e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.34e-1)"	"unprognostic (9.69e-2)"	"unprognostic (7.76e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.62e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.66e-1)"	"unprognostic (6.54e-2)"
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222832-108369102	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 275.2;Oligodendrocytes: 205.4;Rod photoreceptor cells: 228.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Vesicles	"CAB000102: , HPA067142: AB_2685789"	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"
AXIN1	PPP1R49	ENSG00000103126	"Axin 1"	O15169	16	287440-352723	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"NK-cells: 39.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB012987	Approved		Supported	Nucleoli,Vesicles		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 8: Non-specific - Transcription"	"Cluster 7: NK-cells - Immune response regulation"	"Nucleoli, Vesicles"		"CAB012987: AB_2533178"	"unprognostic (3.81e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.90e-1)"	"unprognostic (7.64e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (3.38e-5)"	"unprognostic (1.23e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.56e-1)"	"unprognostic (4.58e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.57e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.94e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.03e-1)"
BIRC3	"API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49"	ENSG00000023445	"Baculoviral IAP repeat containing 3"	Q13489	11	102317450-102339403	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 89.0;lymphoid tissue: 141.5"	"Cell type enhanced"	"Detected in many"		"granulocytes: 737.3;Langerhans cells: 1603.7;monocytes: 693.9;Proximal enterocytes: 883.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"memory B-cell: 209.0;naive B-cell: 159.9"	"Group enriched"	"Detected in all"	13	"B-cells: 209.0;T-cells: 83.6"	"Cancer enhanced"	"Detected in many"		"lymphoma: 122.5"	"Pancreas - Ductal cells, Thyroid - T-cells"	"Low region specificity"	"Detected in all"							HPA002317	Enhanced	Approved	Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 9: Lymphoid cancers - Immune response"	"Cluster 75: Myeloid cells - Innate immune response"	"Nucleoplasm, Cytosol"		"HPA002317: AB_1846748"	"prognostic favorable (3.60e-4)"	"unprognostic (2.89e-1)"	"prognostic favorable (9.35e-4)"	"unprognostic (3.28e-2)"	"prognostic unfavorable (7.28e-4)"	"unprognostic (5.83e-3)"	"unprognostic (2.23e-1)"	"unprognostic (3.88e-3)"	"unprognostic (9.62e-2)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (3.03e-4)"	"unprognostic (3.21e-1)"	"prognostic unfavorable (6.66e-6)"	"unprognostic (6.42e-2)"	"unprognostic (6.23e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.85e-2)"
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1 DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 39.9;Granulosa cells: 36.7;Spermatocytes: 116.9;Spermatogonia: 53.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3"	"Group enriched"	"Detected in all"	6	"dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7"	"Low cancer specificity"	"Detected in all"			"Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"		NA	Yes			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611"	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2 DNA repair associated"	P51587	13	32315086-32400268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 47.7;Spermatocytes: 125.4;Spermatogonia: 73.9"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Macrophages, Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Not detected"	"Not detected"							HPA026815	Uncertain		Supported	Nucleoplasm,Cytosol		Yes	No			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 13: Non-specific - Nuclear processes"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 159.5;Early spermatids: 226.2;Ionocytes: 137.6;Late spermatids: 448.0;Respiratory ciliated cells: 183.1"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 538.8"	"Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA073143"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 48: Non-specific - RNA binding"	"Cluster 74: Pancreatic cells - Mixed function"	Nucleoplasm	Cytosol	"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA073143: "	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"
CDKN2C	"INK4C, p18"	ENSG00000123080	"Cyclin dependent kinase inhibitor 2C"	P42773	1	50960745-50974634	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adipose tissue: 98.4;lymphoid tissue: 96.2"	"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005303, CAB018398, HPA019057, HPA019764"	Approved		Approved	Nucleoplasm,Cytosol		NA	Yes			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 34: Non-specific - Transcription"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 52: Endometrial stromal cells - ECM organization"	"Nucleoplasm, Cytosol"		"CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866"	"unprognostic (4.07e-2)"	"unprognostic (1.47e-3)"	"unprognostic (2.89e-1)"	"unprognostic (4.86e-2)"	"unprognostic (6.70e-2)"	"unprognostic (4.76e-3)"	"prognostic unfavorable (1.58e-4)"	"unprognostic (1.59e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.71e-1)"	"unprognostic (2.28e-1)"	"unprognostic (2.38e-1)"	"prognostic unfavorable (1.70e-10)"	"unprognostic (2.55e-2)"	"unprognostic (2.12e-1)"	"unprognostic (6.45e-2)"	"unprognostic (1.24e-1)"
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"FA complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.2;testis: 21.6"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 48.0;Spermatogonia: 30.4;Syncytiotrophoblasts: 25.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm		NA	Yes			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 36: Non-specific - Unknown function"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm		"HPA063236: AB_2684966"	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"FA complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 24.6"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 128.6;Hepatocytes: 39.0;Late spermatids: 131.5;Microglial cells: 48.3;Oligodendrocytes: 46.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	7	"basophil: 8.8"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 8.8"	"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 55: Non-specific - Unknown function"	"Cluster 49: Early spermatids - Spermatogenesis"	Nucleoplasm		"CAB017793: , HPA030771: AB_2673604"	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favorable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"FA complementation group D2"	Q9BXW9	3	10026414-10101932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 24.0;Spermatocytes: 63.3;Spermatogonia: 25.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 6: BEWO - Unknown function"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: AB_2685110"	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavorable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"
FBXO11	"FBX11, UBR6"	ENSG00000138081	"F-box protein 11"	Q86XK2	2	47789316-47906498	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002690			Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 21: Non-specific - Transcription"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 75: Myeloid cells - Innate immune response"	"Nucleoplasm, Nucleoli"		"HPA002690: AB_1848448"	"unprognostic (1.18e-1)"	"unprognostic (8.65e-3)"	"unprognostic (3.93e-2)"	"unprognostic (2.05e-2)"	"unprognostic (7.92e-2)"	"unprognostic (1.42e-1)"	"unprognostic (3.85e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.82e-2)"	"unprognostic (5.77e-2)"	"unprognostic (2.33e-2)"	"unprognostic (3.21e-2)"	"unprognostic (1.55e-1)"	"unprognostic (3.71e-1)"	"unprognostic (2.19e-1)"	"unprognostic (3.20e-2)"
FBXW7	"AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10"	ENSG00000109670	"F-box and WD repeat domain containing 7"	Q969H0	4	152320544-152536092	"Cancer-related genes, Predicted intracellular proteins"	"Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 66.9"	"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 522.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 23.5"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013793, CAB029987"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 38: Neurons - Neuronal signaling"	"Nucleoplasm, Vesicles"		"CAB013793: AB_2533451, CAB029987: AB_2246842"	"unprognostic (3.32e-1)"	"unprognostic (9.02e-2)"	"unprognostic (1.84e-2)"	"unprognostic (3.08e-2)"	"unprognostic (3.87e-1)"	"unprognostic (1.36e-3)"	"unprognostic (4.37e-1)"	"unprognostic (1.94e-1)"	"unprognostic (8.28e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.32e-3)"	"unprognostic (3.19e-2)"	"prognostic unfavorable (1.52e-4)"	"unprognostic (3.38e-2)"	"unprognostic (1.41e-1)"	"unprognostic (5.49e-3)"	"unprognostic (2.17e-3)"
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985594	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 574.9"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 55.1;Extravillous trophoblasts: 70.5;Fibroblasts: 243.6;Muller glia cells: 71.1;Smooth muscle cells: 96.8;Syncytiotrophoblasts: 119.0"	"Cancer enriched"	"Detected in all"	4	"liver cancer: 269.0"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2"	"Lineage enhanced"	"Detected in single"		"T-cells: 1.8"	"Group enriched"	"Detected in many"	5	"Gastric cancer: 93.1;liver cancer: 297.4;Rhabdoid: 106.3;testis cancer: 233.8"	"Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006316			Supported	"Plasma membrane"		NA	NA		27000	"Cluster 32: T-cells - Unknown function"	"Cluster 28: Placenta - Pregnancy"	"Cluster 35: Liver cancer - Metabolism"	"Cluster 53: Connective tissue cells - ECM organization"	"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavorable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"
IKZF1	"hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1"	ENSG00000185811	"IKAROS family zinc finger 1"	Q13422	7	50304068-50405101	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Cell cycle, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	9	"bone marrow: 173.0;lymphoid tissue: 112.5"	"Cell type enhanced"	"Detected in many"		"B-cells: 161.5;dendritic cells: 378.3;Langerhans cells: 115.3;monocytes: 150.7;NK-cells: 323.4;T-cells: 244.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in some"	131	"Leukemia: 92.0;lymphoma: 124.9;Myeloma: 43.3"	"Adipose visceral - T-cells, Colon - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB009247, HPA035221, HPA035222"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 7: NK-cells - Immune response regulation"	Nucleoplasm	Cytosol	"CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525"	"prognostic favorable (4.28e-4)"	"prognostic favorable (2.02e-4)"	"unprognostic (2.49e-3)"	"unprognostic (2.41e-3)"	"unprognostic (5.59e-1)"	"prognostic favorable (8.63e-4)"	"unprognostic (1.45e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-2)"	"unprognostic (2.43e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.69e-3)"	"unprognostic (1.71e-1)"	"unprognostic (2.84e-2)"	"unprognostic (6.77e-2)"	"unprognostic (4.67e-2)"
KDM6A	UTX	ENSG00000147050	"Lysine demethylase 6A"	O15550	X	44873188-45112779	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 113.1;Oligodendrocyte precursor cells: 113.1;Oligodendrocytes: 249.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Sertoli cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000568, HPA001165, HPA002111"	Enhanced		Approved	"Nucleoplasm,Nucleoli,Nucleoli rim"	"Intracellular and membrane"	NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 46: Non-specific - Unknown function"	"Cluster 1: T-cells - Immune response"	"Nucleoli, Nucleoli rim"	Nucleoplasm	"HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704"	"unprognostic (1.73e-3)"	"unprognostic (6.86e-3)"	"unprognostic (1.45e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.58e-3)"	"unprognostic (8.22e-3)"	"unprognostic (3.23e-1)"	"unprognostic (2.44e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.07e-1)"	"unprognostic (2.73e-1)"	"unprognostic (2.24e-2)"	"unprognostic (5.18e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.16e-2)"
LATS2		ENSG00000150457	"Large tumor suppressor kinase 2"	Q9NRM7	13	20973036-21061586	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 127.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039191, HPA049037"	Approved		Supported	"Centriolar satellite,Cytosol"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 75: Myeloid cells - Innate immune response"	"Centriolar satellite, Cytosol"		"HPA039191: AB_2676385, HPA049037: AB_2680609"	"unprognostic (2.77e-1)"	"prognostic unfavorable (3.26e-4)"	"unprognostic (6.22e-3)"	"unprognostic (3.38e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.84e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.16e-3)"	"unprognostic (4.48e-1)"	"unprognostic (6.57e-3)"	"unprognostic (8.03e-2)"	"unprognostic (4.92e-2)"	"unprognostic (7.85e-2)"	"unprognostic (1.66e-2)"	"unprognostic (1.25e-1)"	"unprognostic (7.97e-2)"	"unprognostic (1.11e-2)"
LRP1B	"LRP-DIT, LRPDIT"	ENSG00000168702	"LDL receptor related protein 1B"	Q9NZR2	2	140231423-142131016	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Endocytosis	Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 22.5"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 2053.8;Excitatory neurons: 3694.4;Inhibitory neurons: 2847.8;Oligodendrocyte precursor cells: 5332.9;Oligodendrocytes: 1135.7"	"Cancer enhanced"	"Detected in some"		"breast cancer: 0.8;glioma: 1.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Rhabdoid: 3.2"	"Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA069094, HPA074788"	Approved		Approved	Vesicles		NA	NA		370000		"Cluster 10: Brain - Neuronal signaling"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 38: Neurons - Neuronal signaling"	Vesicles		"HPA069094: AB_2686082, HPA074788: AB_2797273"	"unprognostic (5.31e-4)"	"unprognostic (3.68e-2)"	"unprognostic (2.61e-1)"	"unprognostic (7.36e-4)"	"unprognostic (5.19e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.00e-2)"	"unprognostic (3.49e-1)"	"unprognostic (3.75e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.64e-3)"	"unprognostic (1.05e-1)"	"unprognostic (2.94e-3)"	"unprognostic (4.85e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.66e-2)"	"unprognostic (1.36e-1)"
MAP2K4	"JNKK1, MEK4, MKK4, PRKMK4, SERK1"	ENSG00000065559	"Mitogen-activated protein kinase kinase 4"	P45985	17	12020829-12143830	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Stress response"	"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 223.6;Inhibitory neurons: 184.9;Oligodendrocyte precursor cells: 142.0;Oligodendrocytes: 191.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 10.4"	"Low lineage specificity"	"Detected in all"			"Cancer enriched"	"Detected in all"	8	"testis cancer: 177.7"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB007751, HPA060074"	Enhanced		Approved	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 47: Non-specific - Unknown function"	"Cluster 49: Non-specific - Unknown function"	"Cluster 38: Neurons - Neuronal signaling"	Nucleoplasm	"Cell Junctions"	"CAB007751: , HPA060074: AB_2684197"	"unprognostic (1.55e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.47e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.89e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.93e-3)"	"unprognostic (2.53e-1)"	"unprognostic (2.76e-3)"	"unprognostic (4.82e-2)"	"unprognostic (5.32e-3)"	"unprognostic (3.13e-1)"	"unprognostic (2.30e-1)"	"unprognostic (7.00e-2)"	"unprognostic (1.79e-1)"
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 16: Non-specific - RNA binding"	Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favorable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 5: Non-specific - Unknown function"	"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 84.4"	"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867, CAB080131"	Supported		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , CAB080131: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 246.1;Excitatory neurons: 320.6;Inhibitory neurons: 403.2;Oligodendrocyte precursor cells: 410.1;Oligodendrocytes: 299.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria		No	No			"Cluster 20: T-cells - T-cell receptor"	"Cluster 21: Non-specific - Transcription"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 37: Neurons - Neuronal signaling"	Mitochondria		"HPA045502: AB_2679352"	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 69.0;Late spermatids: 122.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 39: Non-specific - Unknown function"	"Cluster 74: Pancreatic cells - Mixed function"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favorable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"
PAX5	BSAP	ENSG00000196092	"Paired box 5"	Q02548	9	36833269-37034268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation"	"Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	4	"lymphoid tissue: 39.7"	"Cell type enriched"	"Detected in some"	9	"B-cells: 112.8"	"Low cancer specificity"	"Detected in some"			"Region enhanced"	"Detected in many"		"midbrain: 6.5"	"Group enriched"	"Detected in some"	43	"memory B-cell: 39.0;naive B-cell: 26.0"	"Lineage enriched"	"Detected in single"	52	"B-cells: 39.0"	"Group enriched"	"Detected in some"	11	"Leukemia: 32.8;lymphoma: 76.6"	"Lung - B-cells, Skin - Outer root sheath cells"	"Region enriched"	"Detected in single"	11	"midbrain: 3.9"	"Low region specificity"	"Detected in all"			"CAB026269, CAB026869, HPA056394"	Enhanced	Supported	Supported	Nucleoplasm		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 62: B-cells - B-cell activation"	Nucleoplasm		"CAB026269: , CAB026869: , HPA056394: AB_2683116"	"unprognostic (4.69e-4)"	"unprognostic (3.83e-1)"	"unprognostic (9.13e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.65e-2)"	"unprognostic (1.15e-1)"	"unprognostic (2.09e-2)"	"unprognostic (2.95e-2)"	"unprognostic (2.48e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.11e-3)"	"unprognostic (3.15e-1)"	"unprognostic (8.96e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.01e-1)"
PBRM1	"BAF180, PB1"	ENSG00000163939	"Polybromo 1"	Q86U86	3	52545352-52685917	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015629, HPA059373"	Uncertain		Enhanced	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 5: Non-specific - Unknown function"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"HPA015629: AB_1855012, HPA059373: AB_2683994"	"unprognostic (1.87e-1)"	"unprognostic (1.73e-1)"	"unprognostic (1.91e-2)"	"unprognostic (2.00e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.02e-2)"	"unprognostic (9.54e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.99e-2)"	"unprognostic (4.32e-2)"	"unprognostic (2.89e-3)"	"unprognostic (3.06e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.06e-1)"
PRDM1	"BLIMP1, PRDI-BF1"	ENSG00000057657	"PR/SET domain 1"	O75626	6	105993463-106109939	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation"	"DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"esophagus: 55.2"	"Cell type enhanced"	"Detected in many"		"Langerhans cells: 238.5;NK-cells: 290.6;Plasma cells: 690.4;T-cells: 215.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4"	"Group enriched"	"Detected in many"	5	"granulocytes: 12.5;T-cells: 34.0"	"Cancer enriched"	"Detected in many"	4	"Myeloma: 92.7"	"Colon - T-cells, Prostate - T-cells"	"Region enriched"	"Detected in single"	6	"olfactory bulb: 3.6"	"Low region specificity"	"Detected in many"			"HPA030033, HPA075427"	Approved		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 45: Plasma cells - Humoral immune response"	Nucleoli	Nucleoplasm	"HPA030033: AB_10601050, HPA075427: "	"unprognostic (9.60e-2)"	"unprognostic (3.28e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.98e-2)"	"unprognostic (4.03e-1)"	"unprognostic (3.77e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.81e-1)"	"unprognostic (3.50e-2)"	"unprognostic (7.56e-2)"	"prognostic unfavorable (9.81e-5)"	"unprognostic (1.52e-1)"	"unprognostic (3.51e-1)"	"unprognostic (2.45e-3)"	"unprognostic (7.90e-2)"
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids"	"Low region specificity"	"Detected in all"							"CAB004076, HPA031335, CAB080153, CAB080155, CAB080157"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 72: Smooth muscle cells - ECM organization"	Cytosol	Nucleoplasm	"CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303744-48599436	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 252.8;Melanocytes: 282.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 13: Non-specific - Nuclear processes"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008"	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 130.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019154, CAB080136"	Approved		Supported	Nucleoplasm,Centrosome,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 17: Granulosa cells - Transcription regulation"	"Nucleoplasm, Cytosol"	Centrosome	"CAB080136: , HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favorable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838009	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 253.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"Myeloma: 21.4"	"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 62: B-cells - B-cell activation"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favorable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228431	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 152.3;Late spermatids: 360.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 9.9"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 59: Non-specific - Translation"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 51: Late spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847"	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favorable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favorable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"
SUFU	"PRO1280, SUFUH, SUFUXL"	ENSG00000107882	"SUFU negative regulator of hedgehog signaling"	Q9UMX1	10	102503972-102633535	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"Developmental protein"	"Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 61.3;Late spermatids: 146.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008700	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 36: Spermatids - Spermatogenesis"	Nucleoplasm		"HPA008700: AB_1080125"	"unprognostic (1.55e-1)"	"unprognostic (4.00e-2)"	"unprognostic (5.14e-2)"	"unprognostic (1.33e-1)"	"unprognostic (4.69e-2)"	"unprognostic (5.68e-2)"	"unprognostic (3.69e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.64e-1)"	"unprognostic (3.15e-3)"	"unprognostic (9.60e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.72e-3)"	"unprognostic (1.82e-1)"	"unprognostic (1.44e-1)"	"unprognostic (5.10e-2)"	"unprognostic (3.82e-3)"
TNFAIP3	"A20, OTUD7C"	ENSG00000118503	"TNF alpha induced protein 3"	P21580	6	137867214-137883312	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Inflammatory response, Ubl conjugation pathway"	"DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 519.5"	"Cell type enhanced"	"Detected in many"		"Glandular and luminal cells: 1484.6;granulocytes: 1660.0;monocytes: 885.5;T-cells: 735.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"Myeloma: 95.2"	"Pancreas - Ductal cells, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002116	Approved		Approved	Centrosome,Cytosol		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 75: Myeloid cells - Innate immune response"	"Centrosome, Cytosol"		"HPA002116: AB_1858162"	"unprognostic (5.50e-3)"	"unprognostic (9.98e-3)"	"unprognostic (3.06e-2)"	"unprognostic (1.01e-2)"	"unprognostic (4.01e-2)"	"unprognostic (9.47e-2)"	"unprognostic (5.01e-3)"	"unprognostic (4.40e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.06e-1)"	"prognostic unfavorable (6.05e-4)"	"unprognostic (6.06e-2)"	"unprognostic (3.55e-3)"	"unprognostic (1.27e-1)"	"unprognostic (6.29e-2)"
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in all"	4	"Late spermatids: 412.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 55: Non-specific - Unknown function"	"Cluster 6: Late spermatids - Spermatogenesis"	Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666"	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favorable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favorable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047967-2089491	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Basal prostatic cells: 144.6;Horizontal cells: 126.3;Rod photoreceptor cells: 161.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 8: Non-specific - Transcription"	"Cluster 70: Basal prostatic cells - Lipid metabolism"	Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848"	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favorable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141778-10153667	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031631, HPA031632, HPA068954"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 5: Non-specific - Unknown function"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm	Cytosol	"HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: "	"prognostic unfavorable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favorable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"WT1 transcription factor"	P19544	11	32387775-32435564	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8"	"Cell type enhanced"	"Detected in some"		"Collecting duct cells: 29.5;Endometrial stromal cells: 81.6;Sertoli cells: 135.4;Thymic epithelial cells: 80.7"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Leukemia: 10.0"	"Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Sertoli cells"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm,Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 10: Ovarian & Endometrial cancers - Unknown function"	"Cluster 52: Endometrial stromal cells - ECM organization"	Nucleoplasm	Cytosol	"CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279"	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"