Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
ACVR2A	"ACTRII, ACVR2"	ENSG00000121989	"Activin A receptor type 2A"	P27037	2	147844517-147930826	"Cancer-related genes, Enzymes, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 61.5;Inhibitory neurons: 61.9;Oligodendrocyte precursor cells: 81.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046997	Approved		Approved	Cytosol		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 42: Sarcoma - Muscle contraction"	"Cluster 53: Connective tissue cells - ECM organization"	Cytosol		"HPA046997: AB_10970077"	"unprognostic (4.55e-2)"	"unprognostic (2.26e-2)"	"unprognostic (2.09e-1)"	"unprognostic (7.34e-3)"	"unprognostic (2.75e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.41e-3)"	"unprognostic (8.73e-3)"	"unprognostic (1.30e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.52e-1)"	"prognostic favorable (1.62e-4)"	"unprognostic (1.16e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.95e-1)"	"unprognostic (3.99e-2)"
AMER1	"FAM123B, FLJ39827, RP11-403E24.2, WTX"	ENSG00000184675	"APC membrane recruitment protein 1"	Q5JTC6	X	64185117-64205708	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"tongue: 15.3"	"Cell type enhanced"	"Detected in many"		"Theca cells: 6.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065214, HPA065265"	Approved		Supported	"Nuclear bodies,Vesicles,Plasma membrane"		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 48: Non-specific - RNA binding"	"Cluster 16: Non-specific - RNA binding"	"Nuclear bodies"	"Vesicles, Plasma membrane"	"HPA065214: AB_2685435, HPA065265: AB_2685450"	"unprognostic (1.56e-2)"	"unprognostic (8.85e-2)"	"unprognostic (6.86e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.75e-1)"	"unprognostic (6.31e-2)"	"unprognostic (3.43e-1)"	"unprognostic (4.69e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.19e-2)"	"unprognostic (2.89e-1)"
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC regulator of WNT signaling pathway"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 52.8"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 519.7;Inhibitory neurons: 231.0;Oligodendrocyte precursor cells: 188.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013349, HPA013362"	Supported		Supported	"Golgi apparatus,Plasma membrane"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 57: Non-specific - Translation"	"Cluster 63: Astrocytes - Nervous system maintenance"	"Plasma membrane"	"Golgi apparatus"	"HPA013349: AB_1844913, HPA013362: "	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"
ARID1A	"B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1"	ENSG00000117713	"AT-rich interaction domain 1A"	O14497	1	26693236-26782104	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005456, CAB016334"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"CAB016334: AB_673396, HPA005456: AB_1078205"	"unprognostic (2.83e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.89e-2)"	"prognostic unfavorable (4.18e-4)"	"unprognostic (3.02e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.34e-1)"	"unprognostic (9.69e-2)"	"unprognostic (7.76e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.62e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.66e-1)"	"unprognostic (6.54e-2)"
ARID1B	"6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R"	ENSG00000049618	"AT-rich interaction domain 1B"	Q8NFD5	6	156776020-157210779	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Inhibitory neurons: 464.2;Oligodendrocytes: 475.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016511, HPA075291"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 50: Non-specific - Ribosome"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm		"HPA016511: AB_1845008, HPA075291: AB_2686743"	"prognostic unfavorable (1.04e-4)"	"unprognostic (9.82e-2)"	"unprognostic (1.73e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.47e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.73e-2)"	"unprognostic (2.89e-1)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (4.16e-4)"	"unprognostic (2.53e-1)"	"unprognostic (5.33e-2)"	"unprognostic (1.07e-3)"	"unprognostic (2.46e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.53e-1)"	"unprognostic (1.16e-1)"
ARID2	"BAF200, DKFZp686G052, FLJ30619, KIAA1557"	ENSG00000189079	"AT-rich interaction domain 2"	Q68CP9	12	45729706-45908040	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 391.5;Late spermatids: 270.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA063044			Supported	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 49: Early spermatids - Spermatogenesis"	Nucleoplasm	"Plasma membrane"	"HPA063044: AB_2684929"	"unprognostic (8.41e-2)"	"unprognostic (1.03e-1)"	"unprognostic (4.02e-2)"	"unprognostic (3.94e-2)"	"unprognostic (4.15e-2)"	"prognostic favorable (5.75e-4)"	"unprognostic (1.26e-2)"	"unprognostic (9.71e-2)"	"unprognostic (9.04e-2)"	"unprognostic (5.57e-2)"	"unprognostic (1.34e-1)"	"unprognostic (2.47e-1)"	"unprognostic (1.12e-2)"	"unprognostic (9.21e-2)"	"unprognostic (3.02e-1)"	"unprognostic (2.00e-1)"	"unprognostic (6.53e-2)"
ASXL1	KIAA0978	ENSG00000171456	"ASXL transcriptional regulator 1"	Q8IXJ9	20	32358330-32439319	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation, Ubl conjugation pathway"	"Chromatin regulator, Repressor"	"Cancer-related genes, Craniosynostosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA064156			Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 11: Non-specific - Transcription"	"Nucleoplasm, Nucleoli"		"HPA064156: AB_2685200"	"unprognostic (1.49e-1)"	"unprognostic (5.97e-2)"	"unprognostic (8.36e-2)"	"prognostic unfavorable (2.86e-4)"	"unprognostic (6.69e-2)"	"prognostic favorable (9.16e-4)"	"unprognostic (2.01e-3)"	"unprognostic (2.89e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-1)"	"unprognostic (4.32e-2)"	"unprognostic (3.21e-2)"	"unprognostic (1.84e-3)"	"unprognostic (5.47e-2)"	"unprognostic (1.90e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.06e-1)"
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222832-108369102	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 275.2;Oligodendrocytes: 205.4;Rod photoreceptor cells: 228.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Vesicles	"CAB000102: , HPA067142: AB_2685789"	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"
ATRX	"JMS, MRX52, RAD54, XH2, XNP"	ENSG00000085224	"ATRX chromatin remodeler"	P46100	X	77504880-77786233	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"DNA damage, DNA repair, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001906, CAB009372, HPA064684, CAB068176"	Supported		Supported	"Nuclear bodies"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 48: Non-specific - RNA binding"	"Cluster 64: Non-specific - Transcription"	"Nuclear bodies"		"CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321"	"unprognostic (1.77e-2)"	"unprognostic (1.55e-1)"	"unprognostic (6.65e-2)"	"unprognostic (4.37e-2)"	"unprognostic (1.67e-1)"	"unprognostic (9.69e-2)"	"unprognostic (8.11e-2)"	"unprognostic (1.15e-2)"	"unprognostic (6.04e-2)"	"unprognostic (2.35e-2)"	"unprognostic (1.09e-1)"	"unprognostic (5.80e-2)"	"unprognostic (5.14e-3)"	"unprognostic (1.50e-1)"	"unprognostic (6.19e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.24e-1)"
AXIN1	PPP1R49	ENSG00000103126	"Axin 1"	O15169	16	287440-352723	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"NK-cells: 39.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB012987	Approved		Supported	Nucleoli,Vesicles		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 8: Non-specific - Transcription"	"Cluster 7: NK-cells - Immune response regulation"	"Nucleoli, Vesicles"		"CAB012987: AB_2533178"	"unprognostic (3.81e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.90e-1)"	"unprognostic (7.64e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (3.38e-5)"	"unprognostic (1.23e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.56e-1)"	"unprognostic (4.58e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.57e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.94e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.03e-1)"
AXIN2	"DKFZp781B0869, MGC126582"	ENSG00000168646	"Axin 2"	Q9Y2T1	17	65528563-65561648	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 118.0"	"Cancer enhanced"	"Detected in all"		"colorectal cancer: 33.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 3.2"	"Low lineage specificity"	"Detected in many"			"Cancer enhanced"	"Detected in many"		"colorectal cancer: 115.5;Gastric cancer: 90.4"	"Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012283, CAB017783"	Approved		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 2: DU4475 - Unknown function"	"Cluster 54: Extravillous trophoblasts - Unknown function"	"Nucleoplasm, Plasma membrane, Cytosol"		"CAB012283: AB_2290204, CAB017783: "	"unprognostic (1.31e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.48e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.57e-2)"	"unprognostic (8.84e-3)"	"prognostic favorable (6.58e-4)"	"unprognostic (1.98e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.45e-2)"	"unprognostic (2.10e-1)"	"unprognostic (2.74e-1)"	"unprognostic (1.25e-1)"
B2M		ENSG00000166710	Beta-2-microglobulin	P61769	15	44711487-44718851	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters"	Immunity		"Amyloidosis, Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 20362.9;Proximal enterocytes: 18750.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skeletal muscle - Endothelial cells, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002572, HPA006361"	Enhanced		Enhanced	"Golgi apparatus,Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	1790000000	2100000000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 64: Macrophages - Immune response"	"Cluster 30: Non-specific - Antiviral immune response"	"Cluster 19: Macrophages - Innate immune response"	"Golgi apparatus, Plasma membrane"	Cytosol	"CAB002572: AB_563434, HPA006361: AB_1078278"	"unprognostic (9.45e-2)"	"unprognostic (5.63e-2)"	"unprognostic (3.02e-1)"	"unprognostic (8.14e-2)"	"unprognostic (1.18e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.69e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.44e-3)"	"unprognostic (2.02e-2)"	"unprognostic (4.77e-2)"	"unprognostic (2.39e-1)"	"unprognostic (5.25e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.17e-2)"
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401008-52410008	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	"Chromatin regulator, Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 75.9;Late spermatids: 63.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 5: Non-specific - Unknown function"	"Cluster 36: Spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850"	"unprognostic (1.52e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.96e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.41e-3)"	"unprognostic (8.53e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.15e-1)"	"unprognostic (4.64e-3)"	"unprognostic (3.30e-3)"	"prognostic favorable (3.29e-7)"	"unprognostic (6.37e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.92e-1)"
BCOR	"FLJ20285, KIAA1575"	ENSG00000183337	"BCL6 corepressor"	Q6W2J9	X	40049815-40177329	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Repressor"	"Cancer-related genes, Disease variant, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"							"HPA056308, HPA073591"			Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 59: Non-specific - Translation"	"Cluster 2: DU4475 - Unknown function"	"Cluster 72: Smooth muscle cells - ECM organization"	Nucleoplasm		"HPA056308: AB_2683095, HPA073591: AB_2732227"	"unprognostic (2.75e-2)"	"unprognostic (2.83e-1)"	"unprognostic (2.45e-1)"	"unprognostic (9.26e-2)"	"unprognostic (1.55e-1)"	"unprognostic (9.80e-3)"	"prognostic unfavorable (1.30e-5)"	"unprognostic (3.82e-3)"	"unprognostic (6.86e-2)"	"unprognostic (1.86e-1)"	"unprognostic (4.08e-2)"	"unprognostic (1.18e-1)"	"unprognostic (3.91e-3)"	"unprognostic (6.83e-2)"	"unprognostic (9.57e-2)"	"unprognostic (2.63e-1)"	"unprognostic (1.55e-1)"
BCORL1	"CXorf10, FLJ11362"	ENSG00000085185	"BCL6 corepressor like 1"	Q5H9F3	X	129981107-130058071	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Repressor"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enriched"	"Detected in many"	7	"Syncytiotrophoblasts: 97.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031775, HPA031777, HPA068568"	Uncertain		Approved	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 67: Syncytiotrophoblasts - Pregnancy"	Nucleoplasm	"Plasma membrane"	"HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007"	"unprognostic (8.07e-2)"	"unprognostic (2.78e-2)"	"unprognostic (7.09e-2)"	"prognostic unfavorable (2.20e-5)"	"unprognostic (4.58e-1)"	"unprognostic (1.68e-3)"	"unprognostic (1.96e-3)"	"unprognostic (5.56e-3)"	"unprognostic (2.39e-1)"	"unprognostic (8.02e-2)"	"unprognostic (4.46e-2)"	"unprognostic (2.04e-1)"	"prognostic unfavorable (5.00e-4)"	"unprognostic (9.18e-2)"	"unprognostic (2.60e-2)"	"unprognostic (3.09e-1)"	"unprognostic (1.41e-2)"
BIRC3	"API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49"	ENSG00000023445	"Baculoviral IAP repeat containing 3"	Q13489	11	102317450-102339403	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 89.0;lymphoid tissue: 141.5"	"Cell type enhanced"	"Detected in many"		"granulocytes: 737.3;Langerhans cells: 1603.7;monocytes: 693.9;Proximal enterocytes: 883.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"memory B-cell: 209.0;naive B-cell: 159.9"	"Group enriched"	"Detected in all"	13	"B-cells: 209.0;T-cells: 83.6"	"Cancer enhanced"	"Detected in many"		"lymphoma: 122.5"	"Pancreas - Ductal cells, Thyroid - T-cells"	"Low region specificity"	"Detected in all"							HPA002317	Enhanced	Approved	Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 9: Lymphoid cancers - Immune response"	"Cluster 75: Myeloid cells - Innate immune response"	"Nucleoplasm, Cytosol"		"HPA002317: AB_1846748"	"prognostic favorable (3.60e-4)"	"unprognostic (2.89e-1)"	"prognostic favorable (9.35e-4)"	"unprognostic (3.28e-2)"	"prognostic unfavorable (7.28e-4)"	"unprognostic (5.83e-3)"	"unprognostic (2.23e-1)"	"unprognostic (3.88e-3)"	"unprognostic (9.62e-2)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (3.03e-4)"	"unprognostic (3.21e-1)"	"prognostic unfavorable (6.66e-6)"	"unprognostic (6.42e-2)"	"unprognostic (6.23e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.85e-2)"
BIVM-ERCC5		ENSG00000270181	"BIVM-ERCC5 readthrough"		13	102799110-102875994	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at transcript level"	"Evidence at transcript level"			"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"Excitatory neurons: 6.3;Inhibitory neurons: 7.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in single"		"Kidney cancer: 1.1"										"HPA045845, HPA050126, HPA050374"	Uncertain		Approved	Nucleoplasm		NA	NA				"Cluster 72: Non-specific - Transcription"	"Cluster 68: Kidney - Mixed function"	"Cluster 37: Neurons - Neuronal signaling"	Nucleoplasm		"HPA045845: AB_2679471, HPA050126: AB_2681027, HPA050374: AB_2681106"													"unprognostic (6.01e-2)"				
BLM	"BS, RECQ2, RECQL3"	ENSG00000197299	"BLM RecQ like helicase"	P54132	15	90717346-90816166	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8"	"Cell type enhanced"	"Detected in many"		"monocytes: 36.6;Oligodendrocyte precursor cells: 55.8;Plasma cells: 21.8;Serous glandular cells: 72.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose subcutaneous - Macrophages, Lung - Mitotic cells (Lung), Pancreas - Macrophages, Skin - Mitotic cells (Skin), Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005689	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 21: Serous glandular cells - Salivary secretion"	Nucleoplasm	Cytosol	"HPA005689: AB_1845372"	"unprognostic (2.77e-1)"	"unprognostic (3.82e-3)"	"unprognostic (4.03e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.75e-2)"	"unprognostic (9.89e-2)"	"unprognostic (6.12e-5)"	"unprognostic (2.82e-2)"	"unprognostic (4.55e-3)"	"unprognostic (5.24e-3)"	"unprognostic (1.80e-3)"	"unprognostic (9.12e-2)"	"unprognostic (1.55e-15)"	"unprognostic (6.53e-3)"	"unprognostic (6.55e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.83e-2)"
BMPR1A	"ACVRLK3, ALK3, CD292"	ENSG00000107779	"Bone morphogenetic protein receptor type 1A"	P36894	10	86756601-86932825	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 138.2;Inhibitory neurons: 78.2;Oligodendrocyte precursor cells: 117.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Kidney - Fibroblasts, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019398	Approved		Approved	Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 22: Rhabdoid cancers - Neuronal signaling"	"Cluster 63: Astrocytes - Nervous system maintenance"	Cytosol		"CAB019398: "	"unprognostic (1.36e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.34e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.05e-3)"	"unprognostic (9.34e-2)"	"prognostic unfavorable (8.93e-4)"	"unprognostic (3.64e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (9.24e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.07e-1)"
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1 DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 39.9;Granulosa cells: 36.7;Spermatocytes: 116.9;Spermatogonia: 53.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3"	"Group enriched"	"Detected in all"	6	"dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7"	"Low cancer specificity"	"Detected in all"			"Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"		NA	Yes			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611"	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2 DNA repair associated"	P51587	13	32315086-32400268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 47.7;Spermatocytes: 125.4;Spermatogonia: 73.9"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Macrophages, Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Not detected"	"Not detected"							HPA026815	Uncertain		Supported	Nucleoplasm,Cytosol		Yes	No			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 13: Non-specific - Nuclear processes"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"
BRIP1	"BACH1, FANCJ, OF"	ENSG00000136492	"BRCA1 interacting protein C-terminal helicase 1"	Q9BX63	17	61679139-61863528	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0"	"Group enriched"	"Detected in many"	13	"Early spermatids: 194.4;Late spermatids: 204.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Mitotic cells (Heart), Liver - Hepatocytes, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA005474	Approved		Supported	"Nucleoplasm,Nuclear membrane"		NA	Yes			"Cluster 26: Non-specific - Mitochondria"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 57: Early spermatids - Flagellum & Golgi organization"	"Nucleoplasm, Nuclear membrane"		"HPA005474: AB_2667333"	"unprognostic (1.88e-1)"	"unprognostic (1.55e-2)"	"prognostic favorable (3.45e-5)"	"unprognostic (6.85e-4)"	"unprognostic (3.09e-1)"	"prognostic favorable (3.62e-4)"	"unprognostic (2.60e-3)"	"unprognostic (5.60e-2)"	"unprognostic (5.66e-3)"	"unprognostic (6.71e-2)"	"unprognostic (1.50e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.41e-12)"	"unprognostic (1.19e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.62e-3)"
BUB1B	"Bub1A, BUBR1, MAD3L, SSK1"	ENSG00000156970	"BUB1 mitotic checkpoint serine/threonine kinase B"	O60566	15	40161023-40221123	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2"	"Cell type enriched"	"Detected in many"	4	"Spermatocytes: 81.4"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"naive B-cell: 1.1"	"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)"	"Low region specificity"	"Detected in many"							HPA008419			Supported	Cytosol		Yes	Yes			"Cluster 24: B-cells - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Cytosol		"HPA008419: AB_1078308"	"unprognostic (4.40e-2)"	"unprognostic (2.23e-1)"	"unprognostic (4.65e-2)"	"unprognostic (2.44e-3)"	"unprognostic (9.66e-2)"	"unprognostic (3.52e-2)"	"prognostic unfavorable (7.43e-6)"	"prognostic unfavorable (3.56e-4)"	"unprognostic (3.69e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (1.79e-4)"	"unprognostic (1.76e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.75e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.20e-1)"	"unprognostic (3.94e-2)"
CASP8	"Casp-8, FLICE, MACH, MCH5"	ENSG00000064012	"Caspase 8"	Q14790	2	201233443-201287711	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 66.6"	"Cell type enhanced"	"Detected in many"		"NK-cells: 164.3;T-cells: 91.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA001302, CAB002047, HPA005688, HPA006191"	Approved		Supported	Nucleoplasm,Cytosol		No	No			"Cluster 5: Granulocytes - Unknown function"	"Cluster 2: Immune cells - Immune response"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 1: T-cells - Immune response"	Cytosol	Nucleoplasm	"CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535"	"unprognostic (5.21e-3)"	"unprognostic (2.10e-1)"	"unprognostic (1.83e-2)"	"unprognostic (9.69e-3)"	"unprognostic (2.09e-1)"	"unprognostic (5.60e-2)"	"prognostic unfavorable (3.02e-4)"	"unprognostic (2.10e-1)"	"unprognostic (4.79e-2)"	"prognostic favorable (1.25e-4)"	"unprognostic (7.75e-2)"	"unprognostic (5.11e-2)"	"prognostic unfavorable (1.27e-6)"	"unprognostic (7.67e-3)"	"unprognostic (2.43e-1)"	"unprognostic (2.53e-1)"	"unprognostic (4.53e-3)"
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121983-193254815	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002326, CAB016359, HPA069324"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA002326: , HPA069324: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"
CDH1	"CD324, UVO, uvomorulin"	ENSG00000039068	"Cadherin 1"	P12830	16	68737292-68835537	"Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 197.8"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 258.8;Distal enterocytes: 274.4;Glandular and luminal cells: 317.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	13	"myeloid DC: 1.7;plasmacytoid DC: 4.7"	"Lineage enriched"	"Detected in single"	19	"dendritic cells: 4.7"	"Low cancer specificity"	"Detected in many"			"Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions"		NA	NA		78000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 14: Endometrium - Transcription regulation"	"Plasma membrane, Cell Junctions"	"Golgi apparatus"	"CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369"	"unprognostic (3.95e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.42e-1)"	"unprognostic (2.78e-1)"	"unprognostic (5.04e-3)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.19e-2)"	"unprognostic (3.61e-1)"	"prognostic favorable (2.06e-4)"	"unprognostic (1.21e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.51e-1)"	"unprognostic (5.92e-2)"
CDK12	"CRK7, CRKR, CRKRS, KIAA0904"	ENSG00000167258	"Cyclin dependent kinase 12"	Q9NYV4	17	39461486-39564907	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008038, HPA073305"	Supported		Enhanced	"Nucleoplasm,Nuclear speckles"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 64: Non-specific - Transcription"	"Nucleoplasm, Nuclear speckles"		"HPA008038: AB_1078570, HPA073305: "	"unprognostic (2.02e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.61e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.05e-1)"	"unprognostic (3.19e-1)"	"unprognostic (2.56e-3)"	"unprognostic (2.37e-2)"	"unprognostic (3.86e-2)"	"unprognostic (3.00e-3)"	"unprognostic (6.87e-3)"	"unprognostic (1.86e-1)"	"unprognostic (3.06e-2)"	"unprognostic (9.10e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.22e-2)"	"unprognostic (5.32e-1)"
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 159.5;Early spermatids: 226.2;Ionocytes: 137.6;Late spermatids: 448.0;Respiratory ciliated cells: 183.1"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 538.8"	"Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA073143"	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 48: Non-specific - RNA binding"	"Cluster 74: Pancreatic cells - Mixed function"	Nucleoplasm	Cytosol	"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA073143: "	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"
CEBPA	"C/EBP-alpha, CEBP"	ENSG00000245848	"CCAAT enhancer binding protein alpha"	P49715	19	33299934-33302534	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 98.7;liver: 194.7;skin 1: 118.7"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 83.2;Hepatocytes: 94.3;Hofbauer cells: 80.3;Suprabasal keratinocytes: 104.7;Syncytiotrophoblasts: 231.4"	"Cancer enhanced"	"Detected in all"		"liver cancer: 70.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7"	"Group enriched"	"Detected in many"	15	"dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7"	"Cancer enhanced"	"Detected in many"		"Leukemia: 72.2;liver cancer: 58.7"	"Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Stomach - Chief cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA052734, HPA065037, HPA067937"	Approved		Approved	Nucleoplasm,Vesicles		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 67: Syncytiotrophoblasts - Pregnancy"	Nucleoplasm	Vesicles	"HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927"	"unprognostic (1.80e-1)"	"unprognostic (7.62e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.21e-2)"	"unprognostic (3.38e-1)"	"unprognostic (3.99e-2)"	"unprognostic (1.94e-1)"	"unprognostic (2.43e-3)"	"unprognostic (5.95e-2)"	"unprognostic (3.96e-2)"	"unprognostic (3.09e-1)"	"unprognostic (9.45e-2)"	"unprognostic (8.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (1.98e-1)"	"unprognostic (2.49e-2)"	"unprognostic (2.72e-2)"
CHD4	"Mi-2b, Mi2-BETA"	ENSG00000111642	"Chromodomain helicase DNA binding protein 4"	Q14839	12	6570082-6614524	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia, Thyroid - Thyroid glandular cells"									HPA012008	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"HPA012008: AB_1846633"	"unprognostic (6.11e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.71e-2)"	"unprognostic (6.40e-3)"	"unprognostic (8.99e-2)"	"unprognostic (3.36e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (2.66e-2)"	"unprognostic (1.05e-1)"	"unprognostic (6.85e-2)"	"unprognostic (3.15e-1)"	"unprognostic (3.94e-1)"	"unprognostic (2.06e-1)"	"unprognostic (3.33e-1)"	"unprognostic (1.82e-1)"	"unprognostic (9.84e-2)"	"unprognostic (1.66e-1)"
CNOT3	"KIAA0691, LENG2, NOT3, NOT3H"	ENSG00000088038	"CCR4-NOT transcription complex subunit 3"	O75175	19	54137749-54155681	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation"	"Developmental protein, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006408	Approved		Approved	Cytosol		NA	NA		39000	"Cluster 52: Eosinophils - Transcription"	"Cluster 71: Testis - DNA repair"	"Cluster 4: Non-specific - Transcription"	"Cluster 12: Non-specific - Chromatin organization"	Cytosol		"HPA006408: AB_1078543"	"unprognostic (1.23e-1)"	"unprognostic (2.54e-1)"	"unprognostic (1.75e-2)"	"unprognostic (1.40e-1)"	"unprognostic (4.86e-2)"	"unprognostic (1.90e-1)"	"prognostic unfavorable (2.22e-4)"	"unprognostic (9.06e-2)"	"unprognostic (1.43e-2)"	"unprognostic (2.65e-2)"	"unprognostic (9.30e-3)"	"unprognostic (4.08e-3)"	"prognostic unfavorable (2.77e-4)"	"unprognostic (2.18e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.66e-2)"
COL2A1	"AOM, SEDC, STL1"	ENSG00000139219	"Collagen type II alpha 1 chain"	P02458	12	47972967-48004554	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins"			"Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5"	"Cell type enhanced"	"Detected in some"		"Breast myoepithelial cells: 6.6;Early spermatids: 9.9;Enteroendocrine cells: 27.9;Horizontal cells: 25.0;Late spermatids: 11.7;Muller glia cells: 21.7"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in many"	7	"liver cancer: 78.0"	"Testis - Late spermatids"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"CAB002214, HPA055753"	Approved		Approved	Nucleoplasm	"Secreted to extracellular matrix"	No	NA		1400000		"Cluster 68: Epididymis - Unknown function"	"Cluster 6: BEWO - Unknown function"	"Cluster 55: Endocrine cells - Hormone signaling"	Nucleoplasm		"CAB002214: AB_563666, HPA055753: AB_2682908"	"unprognostic (7.25e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.58e-1)"	"unprognostic (3.44e-1)"	"unprognostic (2.88e-2)"	"unprognostic (3.08e-2)"	"unprognostic (8.63e-2)"	"unprognostic (2.77e-1)"	"unprognostic (1.22e-1)"	"unprognostic (3.12e-2)"	"unprognostic (1.31e-4)"	"unprognostic (2.64e-1)"	"unprognostic (3.44e-3)"	"unprognostic (1.89e-1)"	"unprognostic (2.93e-1)"	"unprognostic (2.07e-1)"	"unprognostic (1.02e-1)"
CREBBP	"CBP, KAT3A, RSTS, RTS"	ENSG00000005339	"CREB binding protein"	Q92793	16	3725054-3880713	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Transcription, Transcription regulation"	"Activator, Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004212, HPA055861"	Supported		Supported	"Nucleoplasm,Nuclear bodies"		No	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 8: Non-specific - Transcription"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm	"Nuclear bodies"	"CAB004212: AB_626817, HPA055861: AB_2682948"	"unprognostic (1.17e-1)"	"unprognostic (8.51e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.63e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.09e-2)"	"unprognostic (9.59e-3)"	"unprognostic (6.98e-2)"	"unprognostic (8.96e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (2.84e-1)"	"prognostic favorable (6.24e-5)"	"unprognostic (1.47e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.97e-2)"	"unprognostic (8.23e-2)"
CSF3R	"CD114, GCSFR"	ENSG00000119535	"Colony stimulating factor 3 receptor"	Q99062	1	36466043-36483278	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	Receptor	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1"	"Group enriched"	"Detected in many"	5	"Cytotrophoblasts: 399.6;Syncytiotrophoblasts: 1372.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"neutrophil: 1962.3"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 1962.3"	"Cancer enriched"	"Detected in some"	19	"Leukemia: 48.0"	"Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB017116, HPA048086"	Enhanced				"Intracellular and membrane"	NA	NA		150000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 66: Myeloid cells - Innate immune response"	"Cluster 67: Syncytiotrophoblasts - Pregnancy"			"CAB017116: , HPA048086: AB_2680257"	"unprognostic (5.57e-3)"	"unprognostic (8.05e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.87e-2)"	"unprognostic (2.88e-1)"	"unprognostic (2.92e-2)"	"unprognostic (2.86e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.83e-1)"	"unprognostic (5.65e-2)"	"unprognostic (2.47e-1)"	"unprognostic (3.44e-1)"	"prognostic unfavorable (5.72e-4)"	"unprognostic (6.33e-2)"	"prognostic unfavorable (3.79e-4)"	"unprognostic (2.03e-1)"	"unprognostic (2.31e-2)"
CTCF	"CFAP108, FAP108"	ENSG00000102974	"CCCTC-binding factor"	P49711	16	67562467-67639177	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Chromosome partition, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Kidney - Fibroblasts, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004122, CAB062550, CAB068181, CAB068182"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 36: Non-specific - Unknown function"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139"	"unprognostic (2.70e-1)"	"unprognostic (4.21e-2)"	"unprognostic (3.41e-2)"	"unprognostic (4.70e-2)"	"unprognostic (4.41e-2)"	"unprognostic (2.70e-1)"	"prognostic unfavorable (4.21e-4)"	"unprognostic (1.71e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.99e-2)"	"prognostic favorable (4.06e-4)"	"unprognostic (3.47e-1)"	"unprognostic (5.99e-2)"	"unprognostic (4.58e-2)"	"unprognostic (1.11e-2)"
CUX1	"CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6"	ENSG00000257923	"Cut like homeobox 1"	"P39880, Q13948"	7	101815904-102283958	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation, Transport"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"non-classical monocyte: 35.0"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003277, HPA003317"	Approved		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 64: Lymphoma - Humoral immune response"	"Cluster 48: Plasmacytoid dendritic cells - Unknown function"	"Nucleoplasm, Golgi apparatus"		"HPA003277: AB_10601804, HPA003317: AB_2666891"	"unprognostic (5.86e-2)"	"unprognostic (5.39e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.73e-1)"	"prognostic unfavorable (7.51e-4)"	"unprognostic (5.85e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.89e-3)"	"unprognostic (2.20e-1)"	"unprognostic (2.50e-1)"	"prognostic favorable (5.72e-7)"	"unprognostic (1.12e-1)"	"unprognostic (8.85e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.97e-1)"
CXCR4	"CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R"	ENSG00000121966	"C-X-C motif chemokine receptor 4"	P61073	2	136114349-136118149	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 1175.1;lymphoid tissue: 549.3"	"Cell type enhanced"	"Detected in many"		"B-cells: 1675.4;dendritic cells: 2180.0;monocytes: 1143.3;NK-cells: 1206.4;Schwann cells: 1000.5;T-cells: 1642.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"Leukemia: 184.9;lymphoma: 220.2;Myeloma: 144.9"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Skin - T-cells, Testis - Macrophages, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 1: T-cells - Immune response"				"unprognostic (1.19e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.12e-2)"	"unprognostic (4.99e-2)"	"unprognostic (9.25e-2)"	"unprognostic (6.06e-2)"	"prognostic favorable (2.05e-4)"	"unprognostic (1.23e-1)"	"unprognostic (2.66e-1)"	"prognostic unfavorable (1.41e-7)"	"prognostic unfavorable (5.67e-4)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	"unprognostic (9.33e-2)"
CYLD	"CYLD1, KIAA0849, USPL2"	ENSG00000083799	"CYLD lysine 63 deubiquitinase"	Q9NQC7	16	50742050-50801935	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway"	"Hydrolase, Protease, Thiol protease"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 94.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011713, HPA050095, HPA077163"	Approved		Supported	"Nucleoplasm,Centriolar satellite"		Yes	No			"Cluster 10: Basophils - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 1: T-cells - Immune response"	"Centriolar satellite"	Nucleoplasm	"CAB011713: AB_731794, HPA050095: AB_2681013, HPA077163: "	"unprognostic (9.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (5.01e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.84e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.87e-2)"	"unprognostic (3.24e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.18e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (8.42e-2)"
DAXX	DAP6	ENSG00000204209	"Death domain associated protein"	Q9UER7	6	33318558-33323016	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction, Transcription, Transcription regulation"	"Chaperone, Chromatin regulator, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002224, HPA008736, HPA008797, CAB025546, HPA065779"	Enhanced		Enhanced	"Nucleoplasm,Nuclear bodies"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 72: Non-specific - Transcription"	"Cluster 15: Non-specific - Protein binding"	"Cluster 7: NK-cells - Immune response regulation"	"Nucleoplasm, Nuclear bodies"		"CAB002224: AB_563688, CAB025546: , HPA008736: AB_1078625, HPA008797: AB_2797218, HPA065779: AB_2685558"	"prognostic favorable (6.05e-4)"	"unprognostic (2.90e-1)"	"unprognostic (9.66e-2)"	"unprognostic (4.04e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.46e-3)"	"unprognostic (3.48e-1)"	"unprognostic (1.92e-1)"	"unprognostic (8.58e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.01e-2)"	"prognostic unfavorable (6.32e-7)"	"unprognostic (2.43e-1)"	"unprognostic (5.37e-1)"	"unprognostic (1.26e-1)"	"unprognostic (1.04e-1)"
DDB2	"DDBB, FLJ34321, UV-DDB2, XPE"	ENSG00000134574	"Damage specific DNA binding protein 2"	Q92466	11	47214465-47239217	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025912, HPA058406"	Enhanced		Supported	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 31: Skin - Epidermis development"	"Cluster 68: Kidney - Mixed function"	"Cluster 23: Langerhans cells - Immune response"	"Nucleoplasm, Cell Junctions"		"CAB025912: , HPA058406: AB_2683708"	"prognostic favorable (7.29e-4)"	"prognostic favorable (1.58e-4)"	"unprognostic (1.49e-1)"	"prognostic favorable (1.20e-4)"	"unprognostic (4.29e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.58e-3)"	"unprognostic (3.53e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.21e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.82e-3)"	"unprognostic (1.07e-1)"
DDR2	"NTRKR3, TKT, TYRO10"	ENSG00000162733	"Discoidin domain receptor tyrosine kinase 2"	Q16832	1	162631373-162787405	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	Osteogenesis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 86.1;Fibroblasts: 127.3;Leydig cells: 64.0;Peritubular cells: 87.2;Smooth muscle cells: 77.2;Thymic epithelial cells: 70.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 43.6"	"Lung - Fibroblast_1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA070112			Approved	"Plasma membrane,Actin filaments"		Yes	No		770000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 15: Smooth muscle cells - Muscle contraction"	"Plasma membrane, Actin filaments"		"HPA070112: AB_2686229"	"unprognostic (4.12e-2)"	"unprognostic (2.73e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.52e-2)"	"unprognostic (1.17e-1)"	"unprognostic (8.16e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.19e-1)"	"unprognostic (6.62e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.15e-1)"	"prognostic unfavorable (1.73e-7)"	"unprognostic (1.56e-3)"	"unprognostic (8.26e-3)"	"unprognostic (7.57e-2)"	"unprognostic (4.10e-3)"
DDX3X	"DBX, DDX14, DDX3, HLP2"	ENSG00000215301	"DEAD-box helicase 3 X-linked"	O00571	X	41333348-41364472	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation"	"DNA-binding, Helicase, Hydrolase, RNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 906.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001648, HPA005631, HPA059585"	Supported	Supported	Approved	Nucleoplasm,Cytosol		NA	NA		260000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 52: Non-specific - Ribosome"	"Cluster 48: Non-specific - RNA binding"	"Cluster 11: Non-specific - Transcription"	Cytosol	Nucleoplasm	"HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073"	"unprognostic (2.42e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.01e-3)"	"unprognostic (1.66e-1)"	"unprognostic (8.12e-2)"	"unprognostic (6.43e-2)"	"unprognostic (1.17e-3)"	"unprognostic (1.88e-1)"	"unprognostic (9.80e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.25e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.95e-1)"	"unprognostic (4.77e-1)"	"unprognostic (9.44e-2)"	"unprognostic (2.93e-2)"
DICER1	"Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1"	ENSG00000100697	"Dicer 1, ribonuclease III"	Q9UPY3	14	95086228-95158010	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Host-virus interaction, RNA-mediated gene silencing"	"Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 395.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000694, CAB068185"	Approved		Supported	Cytosol		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 70: Brain - Nervous system development"	"Cluster 54: Lymphoma - Cytokine signaling"	"Cluster 12: Non-specific - Chromatin organization"	Cytosol		"CAB068185: AB_2665650, HPA000694: AB_1078661"	"unprognostic (2.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.72e-1)"	"unprognostic (6.75e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.52e-3)"	"unprognostic (5.73e-2)"	"unprognostic (9.22e-2)"	"unprognostic (4.22e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.04e-3)"	"unprognostic (3.74e-2)"
DNM2	"CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII"	ENSG00000079805	"Dynamin 2"	P50570	19	10718079-10833488	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Endocytosis, Phagocytosis"	"Hydrolase, Motor protein"	"Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 182.9;Gastric mucus-secreting cells: 174.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Stomach - Gastric mucous cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054246	Supported		Approved	"Golgi apparatus,Cytosol"		NA	NA		230000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 50: Enterocytes - Absorption"	"Golgi apparatus, Cytosol"		"HPA054246: AB_2682427"	"unprognostic (2.30e-1)"	"unprognostic (5.23e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.76e-1)"	"prognostic favorable (8.91e-4)"	"prognostic unfavorable (3.63e-4)"	"unprognostic (1.03e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.89e-1)"	"unprognostic (4.75e-2)"	"unprognostic (5.35e-2)"	"unprognostic (5.47e-2)"	"unprognostic (5.40e-3)"	"unprognostic (2.68e-1)"	"unprognostic (1.61e-1)"	"unprognostic (1.99e-3)"
DNMT3A		ENSG00000119772	"DNA methyltransferase 3 alpha"	Q9Y6K1	2	25227855-25342590	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"		"Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes, Disease variant, Dwarfism, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"Cardiomyocytes: 549.5;Rod photoreceptor cells: 162.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009469, HPA026588"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 21: Neuroblastoma - Neuronal signaling"	"Cluster 77: Cardiomyocytes - Muscle contraction"	Nucleoplasm		"CAB009469: AB_2093990, HPA026588: AB_1847812"	"unprognostic (2.38e-1)"	"unprognostic (2.94e-1)"	"unprognostic (5.65e-2)"	"prognostic unfavorable (1.55e-4)"	"unprognostic (8.38e-2)"	"unprognostic (7.27e-2)"	"prognostic unfavorable (1.58e-4)"	"unprognostic (2.24e-1)"	"unprognostic (7.25e-2)"	"unprognostic (2.72e-1)"	"prognostic favorable (1.18e-4)"	"unprognostic (2.35e-2)"	"prognostic unfavorable (2.49e-4)"	"unprognostic (1.43e-1)"	"unprognostic (1.87e-1)"	"unprognostic (1.14e-1)"	"unprognostic (2.70e-2)"
DROSHA	"Etohi2, HSA242976, RN3, RNASE3L, RNASEN"	ENSG00000113360	"Drosha ribonuclease III"	Q9NRR4	5	31400494-31532196	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Ribosome biogenesis, RNA-mediated gene silencing"	"Endonuclease, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocyte precursor cells: 71.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031150			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 40: Non-specific - Enzymes"	"Cluster 10: Neurons & Oligodendrocytes - Nervous system development"	Nucleoplasm	Cytosol	"HPA031150: AB_2673761"	"unprognostic (8.37e-3)"	"unprognostic (1.81e-1)"	"unprognostic (9.56e-2)"	"prognostic unfavorable (6.79e-4)"	"unprognostic (5.40e-2)"	"unprognostic (6.03e-2)"	"prognostic unfavorable (1.39e-4)"	"unprognostic (3.11e-1)"	"unprognostic (4.08e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.86e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.39e-1)"	"unprognostic (6.94e-2)"	"unprognostic (2.32e-2)"
EP300	"KAT3B, p300"	ENSG00000100393	"E1A binding protein p300"	Q09472	22	41092592-41180077	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000146, HPA003128, HPA004112"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 39: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm		"CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746"	"unprognostic (7.67e-2)"	"unprognostic (5.56e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.52e-1)"	"unprognostic (6.10e-3)"	"unprognostic (1.66e-1)"	"unprognostic (2.21e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.54e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.54e-2)"	"prognostic favorable (7.45e-5)"	"unprognostic (7.97e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.66e-2)"
ERBB3	"HER3, LCCS2"	ENSG00000065361	"Erb-b2 receptor tyrosine kinase 3"	P21860	12	56076799-56103505	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Proximal enterocytes: 210.8;Schwann cells: 220.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"basophil: 2.4;neutrophil: 1.0"	"Lineage enriched"	"Detected in single"	6	"granulocytes: 2.4"	"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025331, HPA045396, HPA070524"	Approved		Supported	"Plasma membrane,Actin filaments"	"Secreted - unknown location"	NA	NA		450000	"Cluster 17: Basophils - Unknown function"	"Cluster 45: Intestine - Brush border"	"Cluster 33: Skin cancer - Membrane components"	"Cluster 25: Schwann cells & Melanocytes - Mixed function"	"Plasma membrane"	"Actin filaments"	"CAB025331: , HPA045396: AB_2679312, HPA070524: "	"unprognostic (2.97e-1)"	"unprognostic (2.71e-2)"	"unprognostic (1.91e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.07e-3)"	"unprognostic (2.31e-3)"	"unprognostic (2.66e-2)"	"unprognostic (9.89e-2)"	"unprognostic (4.30e-2)"	"unprognostic (4.76e-3)"	"unprognostic (5.77e-2)"	"unprognostic (1.06e-2)"	"unprognostic (4.56e-2)"	"unprognostic (1.57e-1)"	"unprognostic (6.72e-3)"	"unprognostic (2.07e-2)"
ERBB4	"ALS19, HER4"	ENSG00000178568	"Erb-b2 receptor tyrosine kinase 4"	Q15303	2	211375717-212538841	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Lactation, Transcription, Transcription regulation"	"Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 16.9;fallopian tube: 11.2"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 1957.3;Inhibitory neurons: 5974.5;Oligodendrocyte precursor cells: 2268.6;Oligodendrocytes: 991.1"	"Group enriched"	"Detected in many"	4	"breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Rhabdoid: 3.9"	"Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000276, HPA012016, CAB025522"	Enhanced					NA	NA		220000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 37: Neurons - Neuronal signaling"			"CAB000276: , CAB025522: , HPA012016: AB_1846541"	"unprognostic (1.48e-1)"	"unprognostic (3.28e-1)"	"unprognostic (4.31e-3)"	"unprognostic (1.76e-3)"	"unprognostic (3.59e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.88e-1)"	"unprognostic (9.56e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.67e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.61e-1)"	"unprognostic (7.14e-3)"	"unprognostic (1.49e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (4.11e-2)"
ERCC2	"EM9, MAG, MGC102762, MGC126218, MGC126219, XPD"	ENSG00000104884	"ERCC excision repair 2, TFIIH core complex helicase subunit"	P18074	19	45349837-45370918	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Granulosa cells: 33.8;Spermatocytes: 30.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005375, HPA038057, HPA069266"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 43: Testis - Unknown function"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 17: Granulosa cells - Transcription regulation"	Nucleoplasm	Cytosol	"CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104"	"unprognostic (1.10e-1)"	"unprognostic (5.48e-1)"	"unprognostic (5.08e-2)"	"unprognostic (9.92e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.41e-1)"	"unprognostic (1.06e-1)"	"prognostic favorable (3.26e-4)"	"unprognostic (3.36e-2)"	"unprognostic (2.44e-3)"	"unprognostic (1.94e-1)"	"unprognostic (5.47e-1)"	"unprognostic (8.99e-2)"	"unprognostic (3.45e-2)"
ERCC4	"FANCQ, RAD1, XPF"	ENSG00000175595	"ERCC excision repair 4, endonuclease catalytic subunit"	Q92889	16	13920154-13952348	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 18.5"	"Cell type enhanced"	"Detected in all"		"Early spermatids: 119.5;Late spermatids: 131.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000156, HPA045828"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 8: Non-specific - Transcription"	"Cluster 36: Spermatids - Spermatogenesis"	"Nucleoplasm, Nuclear bodies"	"Plasma membrane"	"CAB000156: , HPA045828: AB_2679463"	"unprognostic (2.05e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.12e-3)"	"unprognostic (9.41e-2)"	"unprognostic (3.35e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.59e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.49e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.15e-1)"	"unprognostic (6.30e-2)"	"unprognostic (5.88e-4)"
EXT1	"LGCR, LGS, ttv"	ENSG00000182197	"Exostosin glycosyltransferase 1"	Q16394	8	117794490-118111826	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 123.4;Excitatory neurons: 226.2;Inhibitory neurons: 411.0;Microglial cells: 140.5;Oligodendrocyte precursor cells: 156.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044394	Uncertain					NA	Yes		17000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 32: Neurons - Synaptic function"			"HPA044394: AB_10963838"	"unprognostic (1.29e-2)"	"prognostic unfavorable (7.04e-4)"	"unprognostic (2.73e-2)"	"unprognostic (2.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (7.55e-2)"	"unprognostic (1.99e-1)"	"prognostic unfavorable (1.20e-5)"	"unprognostic (1.70e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.31e-2)"	"unprognostic (6.58e-2)"	"unprognostic (1.27e-2)"	"unprognostic (9.84e-2)"	"unprognostic (9.49e-2)"	"prognostic unfavorable (4.64e-4)"	"unprognostic (1.85e-1)"
EXT2	SOTV	ENSG00000151348	"Exostosin glycosyltransferase 2"	Q93063	11	44095673-44251962	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078409			Supported	"Golgi apparatus"		NA	NA		39000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 37: Ovarian cancer RMG-I - Cellular stress response"	"Cluster 53: Connective tissue cells - ECM organization"	"Golgi apparatus"		"HPA078409: AB_2686884"	"unprognostic (5.87e-2)"	"unprognostic (3.05e-3)"	"unprognostic (3.48e-2)"	"unprognostic (3.94e-1)"	"unprognostic (1.42e-1)"	"prognostic unfavorable (2.50e-4)"	"unprognostic (1.77e-3)"	"unprognostic (2.22e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.70e-2)"	"prognostic unfavorable (5.36e-6)"	"unprognostic (7.07e-3)"	"unprognostic (2.97e-1)"	"unprognostic (3.85e-1)"	"unprognostic (1.36e-2)"
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"FA complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.2;testis: 21.6"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 48.0;Spermatogonia: 30.4;Syncytiotrophoblasts: 25.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm		NA	Yes			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 36: Non-specific - Unknown function"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm		"HPA063236: AB_2684966"	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"FA complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 24.6"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 128.6;Hepatocytes: 39.0;Late spermatids: 131.5;Microglial cells: 48.3;Oligodendrocytes: 46.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	7	"basophil: 8.8"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 8.8"	"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 55: Non-specific - Unknown function"	"Cluster 49: Early spermatids - Spermatogenesis"	Nucleoplasm		"CAB017793: , HPA030771: AB_2673604"	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favorable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"FA complementation group D2"	Q9BXW9	3	10026414-10101932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 24.0;Spermatocytes: 63.3;Spermatogonia: 25.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 6: BEWO - Unknown function"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: AB_2685110"	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavorable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"
FANCE	"FACE, FAE"	ENSG00000112039	"FA complementation group E"	Q9HB96	6	35452338-35467102	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 22.7;Extravillous trophoblasts: 121.8;Syncytiotrophoblasts: 49.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013343, CAB014893"	Enhanced		Supported	"Nucleoplasm,Mitotic chromosome,Centrosome"		Yes	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 15: Non-specific - Protein binding"	"Cluster 54: Extravillous trophoblasts - Unknown function"	Nucleoplasm	"Mitotic chromosome, Centrosome"	"CAB014893: , HPA013343: "	"unprognostic (2.66e-1)"	"unprognostic (8.01e-3)"	"unprognostic (7.73e-2)"	"prognostic unfavorable (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.80e-3)"	"prognostic unfavorable (2.08e-9)"	"unprognostic (8.90e-2)"	"unprognostic (5.70e-3)"	"unprognostic (8.41e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.91e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.05e-1)"	"unprognostic (2.44e-2)"	"unprognostic (5.14e-2)"
FANCF	FAF	ENSG00000183161	"FA complementation group F"	Q9NPI8	11	22622533-22625823	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	6	"Early spermatids: 203.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008899			Supported	Nucleoplasm		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 57: Early spermatids - Flagellum & Golgi organization"	Nucleoplasm		"HPA008899: "	"unprognostic (1.16e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.55e-2)"	"unprognostic (8.84e-2)"	"prognostic unfavorable (2.27e-4)"	"unprognostic (4.29e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.74e-3)"	"unprognostic (3.95e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.81e-1)"	"unprognostic (9.14e-2)"	"unprognostic (7.64e-3)"
FANCG	"FAG, XRCC9"	ENSG00000221829	"FA complementation group G"	O15287	9	35073835-35079942	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 17.3;Plasma cells: 16.1;Spermatogonia: 16.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008105, HPA045335"	Approved		Approved	"Nucleoli,Plasma membrane,Cytosol"		NA	Yes			"Cluster 41: Basophils - Cellular respiration"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	"Plasma membrane, Cytosol"	Nucleoli	"CAB008105: AB_2231542, HPA045335: AB_2679292"	"unprognostic (9.41e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.83e-3)"	"prognostic unfavorable (2.02e-4)"	"unprognostic (8.92e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.27e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.62e-2)"	"prognostic unfavorable (2.38e-7)"	"unprognostic (1.14e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.10e-1)"
FAT1	"CDHF7, CDHR8, FAT"	ENSG00000083857	"FAT atypical cadherin 1"	Q14517	4	186587794-186726722	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 119.2"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 113.3;Salivary duct cells: 99.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Breast - Breast myoepithelial cells"	"Low region specificity"	"Detected in all"							"HPA001869, HPA023882"	Enhanced				"Intracellular and membrane"	NA	NA		4600000		"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 5: Bronchus - Unknown function"			"HPA001869: AB_1078818, HPA023882: AB_1848429"	"unprognostic (1.98e-1)"	"unprognostic (4.91e-2)"	"unprognostic (2.50e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.53e-2)"	"unprognostic (5.82e-3)"	"unprognostic (2.31e-1)"	"prognostic unfavorable (4.22e-4)"	"unprognostic (6.10e-2)"	"unprognostic (3.05e-2)"	"unprognostic (1.15e-3)"	"unprognostic (6.80e-2)"	"unprognostic (3.57e-2)"	"unprognostic (8.03e-3)"	"unprognostic (9.41e-2)"	"unprognostic (6.25e-3)"	"unprognostic (4.27e-2)"
FAT4	"CDHF14, CDHR11, FAT-J"	ENSG00000196159	"FAT atypical cadherin 4"	Q6V0I7	4	125314918-125492932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Deafness, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 23.5;Endothelial cells: 30.5;Fibroblasts: 25.2;Inhibitory neurons: 33.9;Microglial cells: 22.8;Oligodendrocytes: 51.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enriched"	"Detected in many"	4	"Bone cancer: 19.0"	"Breast - Fibroblasts, Prostate - Fibroblasts"	"Low region specificity"	"Detected in many"							HPA052819	Approved		Approved	Cytosol		NA	NA		2300000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 14: Bone cancer - Transcription"	"Cluster 37: Neurons - Neuronal signaling"	Cytosol		"HPA052819: AB_2681963"	"unprognostic (1.18e-1)"	"unprognostic (1.77e-1)"	"unprognostic (7.99e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.31e-1)"	"unprognostic (2.81e-4)"	"unprognostic (6.17e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.77e-2)"	"unprognostic (2.78e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.39e-1)"	"prognostic favorable (1.89e-4)"	"unprognostic (2.38e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.30e-2)"	"unprognostic (2.49e-3)"
FBXW7	"AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10"	ENSG00000109670	"F-box and WD repeat domain containing 7"	Q969H0	4	152320544-152536092	"Cancer-related genes, Predicted intracellular proteins"	"Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 66.9"	"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 522.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 23.5"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013793, CAB029987"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 38: Neurons - Neuronal signaling"	"Nucleoplasm, Vesicles"		"CAB013793: AB_2533451, CAB029987: AB_2246842"	"unprognostic (3.32e-1)"	"unprognostic (9.02e-2)"	"unprognostic (1.84e-2)"	"unprognostic (3.08e-2)"	"unprognostic (3.87e-1)"	"unprognostic (1.36e-3)"	"unprognostic (4.37e-1)"	"unprognostic (1.94e-1)"	"unprognostic (8.28e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.32e-3)"	"unprognostic (3.19e-2)"	"prognostic unfavorable (1.52e-4)"	"unprognostic (3.38e-2)"	"unprognostic (1.41e-1)"	"unprognostic (5.49e-3)"	"unprognostic (2.17e-3)"
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 209.0;Early spermatids: 247.9;Syncytiotrophoblasts: 174.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: Non-specific - RNA binding"	"Cluster 18: Non-specific - Mixed function"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 32: Myeloid leukemia - Oxygen transport"	"Cluster 65: Fibroblasts - ECM organization"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"
FUBP1	"FBP, FUBP"	ENSG00000162613	"Far upstream element binding protein 1"	Q96AE4	1	77944055-77979110	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skeletal muscle - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006149	Supported		Enhanced	Nucleoplasm		NA	NA		300000	"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 34: Non-specific - Transcription"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 16: Non-specific - RNA binding"	Nucleoplasm		"HPA006149: AB_1849172"	"unprognostic (4.17e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.35e-3)"	"unprognostic (3.89e-2)"	"unprognostic (3.77e-1)"	"unprognostic (5.65e-2)"	"prognostic unfavorable (9.83e-9)"	"unprognostic (2.32e-2)"	"unprognostic (2.16e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.31e-3)"	"unprognostic (9.80e-3)"	"unprognostic (9.02e-3)"	"unprognostic (1.37e-1)"	"unprognostic (1.67e-1)"	"unprognostic (6.24e-2)"	"unprognostic (9.46e-2)"
GATA3	HDR	ENSG00000107485	"GATA binding protein 3"	P23771	10	8045378-8075198	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Immunity, Innate immunity, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Deafness, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 109.9;skin 1: 172.9"	"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 248.5;Breast glandular cells: 250.7;Cytotrophoblasts: 332.8;Extravillous trophoblasts: 849.3;Syncytiotrophoblasts: 1253.5"	"Group enriched"	"Detected in many"	24	"breast cancer: 190.0;urothelial cancer: 87.0"	"Group enriched"	"Detected in many"	5	"midbrain: 28.3;pons: 12.6"	"Group enriched"	"Detected in many"	41	"gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6"	"Group enriched"	"Detected in many"	57	"NK-cells: 36.1;T-cells: 43.6"	"Cancer enhanced"	"Detected in many"		"breast cancer: 117.0;Neuroblastoma: 151.9"	"Skin - Keratinocyte (other)"	"Region enriched"	"Detected in single"	6	"midbrain: 6.1"	"Group enriched"	"Detected in some"	11	"medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1"	"CAB016217, HPA029730"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 61: Skin - Cornification"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 54: Extravillous trophoblasts - Unknown function"	Nucleoplasm		"CAB016217: AB_2108591, HPA029730: AB_10601907"	"unprognostic (1.70e-1)"	"unprognostic (7.23e-2)"	"unprognostic (3.58e-2)"	"unprognostic (2.00e-1)"	"unprognostic (7.03e-3)"	"unprognostic (4.68e-3)"	"unprognostic (4.23e-2)"	"unprognostic (9.65e-2)"	"unprognostic (2.06e-1)"	"unprognostic (2.55e-1)"	"unprognostic (3.83e-1)"	"unprognostic (1.17e-1)"	"prognostic unfavorable (3.13e-4)"	"unprognostic (1.48e-1)"	"unprognostic (5.16e-2)"	"unprognostic (6.31e-2)"	"unprognostic (1.82e-3)"
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985594	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 574.9"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 55.1;Extravillous trophoblasts: 70.5;Fibroblasts: 243.6;Muller glia cells: 71.1;Smooth muscle cells: 96.8;Syncytiotrophoblasts: 119.0"	"Cancer enriched"	"Detected in all"	4	"liver cancer: 269.0"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2"	"Lineage enhanced"	"Detected in single"		"T-cells: 1.8"	"Group enriched"	"Detected in many"	5	"Gastric cancer: 93.1;liver cancer: 297.4;Rhabdoid: 106.3;testis cancer: 233.8"	"Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_1, Pancreas - Fibroblasts, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006316			Supported	"Plasma membrane"		NA	NA		27000	"Cluster 32: T-cells - Unknown function"	"Cluster 28: Placenta - Pregnancy"	"Cluster 35: Liver cancer - Metabolism"	"Cluster 53: Connective tissue cells - ECM organization"	"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavorable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"
GRIN2A	"GluN2A, NMDAR2A"	ENSG00000183454	"Glutamate ionotropic receptor NMDA type subunit 2A"	Q12879	16	9753404-10182928	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters"	"Ion transport, Transport"	"Ion channel, Ligand-gated ion channel, Receptor"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	10	"brain: 31.7"	"Group enriched"	"Detected in some"	13	"Excitatory neurons: 827.5;Inhibitory neurons: 882.2"	"Cancer enhanced"	"Detected in some"		"ovarian cancer: 0.9"	"Region enhanced"	"Detected in many"		"cerebral cortex: 31.7"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in single"			"Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Thyroid - Fibroblasts"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB022725	Enhanced					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 7: Neuronal cell lines - Stereocilium"	"Cluster 32: Neurons - Synaptic function"			"CAB022725: "	"unprognostic (6.43e-2)"	"unprognostic (2.47e-1)"	"unprognostic (5.97e-2)"	"unprognostic (3.21e-2)"	"unprognostic (3.13e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.08e-1)"	"unprognostic (5.39e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.75e-3)"	"unprognostic (4.79e-3)"	"unprognostic (2.05e-1)"	"unprognostic (3.92e-3)"	"unprognostic (3.33e-2)"
HIF1A	"bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8"	ENSG00000100644	"Hypoxia inducible factor 1 subunit alpha"	Q16665	14	61695513-61748259	"Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 448.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 155.0"	"Lineage enriched"	"Detected in all"	7	"granulocytes: 155.0"	"Low cancer specificity"	"Detected in all"			"Skeletal muscle - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000907, HPA001275, CAB017442"	Approved		Enhanced	"Nucleoplasm,Nuclear bodies"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 20: Connective tissue cells - ECM organization"	"Cluster 33: Macrophages - Degranulation"	Nucleoplasm	"Nuclear bodies"	"CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057"	"unprognostic (1.07e-2)"	"unprognostic (1.13e-3)"	"unprognostic (9.41e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.51e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.94e-3)"	"unprognostic (3.40e-1)"	"unprognostic (4.05e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.77e-2)"	"unprognostic (8.39e-2)"	"unprognostic (1.24e-1)"	"unprognostic (3.23e-2)"	"unprognostic (3.58e-1)"	"unprognostic (7.35e-2)"	"unprognostic (3.88e-2)"
KDM5C	"DXS1272E, JARID1C, MRX13, SMCX, XE169"	ENSG00000126012	"Lysine demethylase 5C"	P41229	X	53191321-53225422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038244, HPA046147"			Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 59: Non-specific - Translation"	"Cluster 48: Non-specific - RNA binding"	"Cluster 48: Plasmacytoid dendritic cells - Unknown function"	Nucleoplasm	Cytosol	"HPA038244: AB_2675911, HPA046147: AB_2679555"	"unprognostic (1.19e-1)"	"unprognostic (1.13e-1)"	"unprognostic (1.56e-2)"	"unprognostic (7.10e-2)"	"unprognostic (9.75e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (2.11e-4)"	"unprognostic (2.08e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.24e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.58e-2)"	"unprognostic (5.05e-3)"	"unprognostic (1.96e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.00e-1)"
KDM6A	UTX	ENSG00000147050	"Lysine demethylase 6A"	O15550	X	44873188-45112779	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Chromatin regulator, Dioxygenase, Oxidoreductase"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 113.1;Oligodendrocyte precursor cells: 113.1;Oligodendrocytes: 249.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Sertoli cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000568, HPA001165, HPA002111"	Enhanced		Approved	"Nucleoplasm,Nucleoli,Nucleoli rim"	"Intracellular and membrane"	NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 46: Non-specific - Unknown function"	"Cluster 1: T-cells - Immune response"	"Nucleoli, Nucleoli rim"	Nucleoplasm	"HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704"	"unprognostic (1.73e-3)"	"unprognostic (6.86e-3)"	"unprognostic (1.45e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.58e-3)"	"unprognostic (8.22e-3)"	"unprognostic (3.23e-1)"	"unprognostic (2.44e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.07e-1)"	"unprognostic (2.73e-1)"	"unprognostic (2.24e-2)"	"unprognostic (5.18e-2)"	"unprognostic (1.26e-1)"	"unprognostic (3.16e-2)"
KEAP1	"INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454"	ENSG00000079999	"Kelch like ECH associated protein 1"	Q14145	19	10486125-10503558	"Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins"	"Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 178.2"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005558, CAB025337"	Approved		Supported	"Nucleoplasm,Centriolar satellite,Cytosol"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 16: Non-specific - RNA binding"	"Nucleoplasm, Centriolar satellite"	Cytosol	"CAB025337: , HPA005558: AB_1079175"	"unprognostic (1.98e-1)"	"prognostic favorable (3.28e-4)"	"unprognostic (1.61e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.42e-1)"	"unprognostic (1.63e-2)"	"unprognostic (2.64e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.48e-1)"	"unprognostic (5.22e-3)"	"unprognostic (2.04e-1)"	"unprognostic (9.99e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.71e-3)"	"unprognostic (5.06e-1)"	"unprognostic (8.18e-2)"	"unprognostic (1.60e-2)"
KLF6	"BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9"	ENSG00000067082	"Kruppel like factor 6"	Q99612	10	3775996-3785281	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 436.6"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013529, HPA069585"	Supported		Supported	Nucleoplasm,Nucleoli,Vesicles,Cytosol		No	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 14: Endometrium - Transcription regulation"	Nucleoplasm	"Nucleoli, Vesicles, Cytosol"	"CAB013529: AB_2533431, HPA069585: AB_2686157"	"unprognostic (1.23e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.47e-3)"	"unprognostic (4.53e-2)"	"unprognostic (1.47e-1)"	"unprognostic (7.55e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.08e-3)"	"unprognostic (1.61e-1)"	"unprognostic (2.83e-2)"	"unprognostic (1.36e-2)"	"unprognostic (2.35e-2)"	"prognostic favorable (2.28e-4)"	"unprognostic (8.07e-3)"	"unprognostic (4.85e-2)"	"unprognostic (6.87e-2)"	"unprognostic (1.37e-2)"
KMT2C	"HALR, KIAA1506, MLL3"	ENSG00000055609	"Lysine methyltransferase 2C"	Q8NEZ4	7	152134922-152436641	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 15.2"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA074736			Approved	Nucleoplasm		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 31: Non-specific - Transcription"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm		"HPA074736: AB_2686709"	"unprognostic (7.75e-2)"	"unprognostic (3.10e-1)"	"unprognostic (2.83e-1)"	"unprognostic (1.33e-2)"	"unprognostic (1.31e-1)"	"unprognostic (5.23e-3)"	"unprognostic (1.09e-1)"	"unprognostic (1.59e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.17e-1)"	"unprognostic (3.45e-1)"	"unprognostic (1.06e-1)"	"prognostic favorable (8.01e-6)"	"unprognostic (1.78e-1)"	"unprognostic (3.83e-1)"	"unprognostic (3.04e-2)"	"unprognostic (2.64e-1)"
KMT2D	"ALR, CAGL114, MLL2, MLL4, TNRC21"	ENSG00000167548	"Lysine methyltransferase 2D"	O14686	12	49018978-49060794	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Methyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.5"	"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035977	Approved		Approved	"Nucleoplasm,Plasma membrane,Cytosol"		Yes	No			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 12: Non-specific - Chromatin organization"	Cytosol	"Nucleoplasm, Plasma membrane"	"HPA035977: AB_10670673"	"unprognostic (8.33e-2)"	"unprognostic (1.49e-1)"	"unprognostic (9.14e-2)"	"unprognostic (2.52e-1)"	"unprognostic (8.07e-2)"	"unprognostic (6.91e-3)"	"unprognostic (7.35e-2)"	"unprognostic (2.29e-1)"	"unprognostic (3.57e-1)"	"unprognostic (5.14e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.07e-1)"	"unprognostic (1.68e-2)"	"unprognostic (7.10e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.20e-2)"	"unprognostic (7.60e-2)"
LATS1	WARTS	ENSG00000131023	"Large tumor suppressor kinase 1"	O95835	6	149658153-149718105	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031804	Approved					NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 15: Non-specific - Protein binding"	"Cluster 64: Non-specific - Transcription"			"HPA031804: AB_10601688"	"unprognostic (4.02e-3)"	"unprognostic (3.80e-3)"	"unprognostic (1.28e-2)"	"unprognostic (1.00e-1)"	"unprognostic (4.40e-2)"	"unprognostic (2.09e-1)"	"unprognostic (6.15e-3)"	"unprognostic (1.29e-2)"	"unprognostic (9.67e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.62e-2)"	"unprognostic (1.92e-1)"	"unprognostic (8.43e-2)"	"unprognostic (2.63e-1)"	"unprognostic (2.65e-1)"
LATS2		ENSG00000150457	"Large tumor suppressor kinase 2"	Q9NRM7	13	20973036-21061586	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 127.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039191, HPA049037"	Approved		Supported	"Centriolar satellite,Cytosol"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 75: Myeloid cells - Innate immune response"	"Centriolar satellite, Cytosol"		"HPA039191: AB_2676385, HPA049037: AB_2680609"	"unprognostic (2.77e-1)"	"prognostic unfavorable (3.26e-4)"	"unprognostic (6.22e-3)"	"unprognostic (3.38e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.84e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.16e-3)"	"unprognostic (4.48e-1)"	"unprognostic (6.57e-3)"	"unprognostic (8.03e-2)"	"unprognostic (4.92e-2)"	"unprognostic (7.85e-2)"	"unprognostic (1.66e-2)"	"unprognostic (1.25e-1)"	"unprognostic (7.97e-2)"	"unprognostic (1.11e-2)"
LEF1	"TCF10, TCF1ALPHA, TCF7L3"	ENSG00000138795	"Lymphoid enhancer binding factor 1"	Q9UJU2	4	108047545-108168956	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation, Wnt signaling pathway"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	19	"lymphoid tissue: 349.2"	"Group enriched"	"Detected in many"	4	"Melanocytes: 47.0;Microglial cells: 141.4;T-cells: 77.4"	"Cancer enhanced"	"Detected in all"		"melanoma: 25.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive CD4 T-cell: 142.6"	"Lineage enriched"	"Detected in many"	4	"T-cells: 142.6"	"Cancer enhanced"	"Detected in many"		"Leukemia: 150.9"	"Liver - T-cells, Skin - Inner root sheath cells, Testis - Early spermatids"	"Region enhanced"	"Detected in all"		"thalamus: 22.6"	"Low region specificity"	"Detected in all"			"HPA002087, CAB019405"	Enhanced		Approved	Nucleoplasm		NA	NA			"Cluster 20: T-cells - T-cell receptor"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 2: T-cells - T-cell receptor"	Nucleoplasm		"CAB019405: AB_823558, HPA002087: AB_1079245"	"unprognostic (1.03e-3)"	"unprognostic (7.36e-3)"	"unprognostic (2.97e-2)"	"prognostic favorable (1.37e-5)"	"unprognostic (9.08e-2)"	"unprognostic (5.24e-2)"	"unprognostic (3.81e-2)"	"unprognostic (1.10e-2)"	"unprognostic (1.77e-1)"	"unprognostic (5.21e-2)"	"unprognostic (9.99e-2)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (2.47e-6)"	"unprognostic (1.12e-1)"	"unprognostic (5.22e-2)"	"unprognostic (7.88e-2)"	"unprognostic (8.91e-2)"
LRP1B	"LRP-DIT, LRPDIT"	ENSG00000168702	"LDL receptor related protein 1B"	Q9NZR2	2	140231423-142131016	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Endocytosis	Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 22.5"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 2053.8;Excitatory neurons: 3694.4;Inhibitory neurons: 2847.8;Oligodendrocyte precursor cells: 5332.9;Oligodendrocytes: 1135.7"	"Cancer enhanced"	"Detected in some"		"breast cancer: 0.8;glioma: 1.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Rhabdoid: 3.2"	"Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA069094, HPA074788"	Approved		Approved	Vesicles		NA	NA		370000		"Cluster 10: Brain - Neuronal signaling"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 38: Neurons - Neuronal signaling"	Vesicles		"HPA069094: AB_2686082, HPA074788: AB_2797273"	"unprognostic (5.31e-4)"	"unprognostic (3.68e-2)"	"unprognostic (2.61e-1)"	"unprognostic (7.36e-4)"	"unprognostic (5.19e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.00e-2)"	"unprognostic (3.49e-1)"	"unprognostic (3.75e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.64e-3)"	"unprognostic (1.05e-1)"	"unprognostic (2.94e-3)"	"unprognostic (4.85e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.66e-2)"	"unprognostic (1.36e-1)"
LZTR1	"BTBD29, LZTR-1"	ENSG00000099949	"Leucine zipper like transcription regulator 1"	Q8N653	22	20982269-20999032	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067852, HPA068772, HPA071248"	Approved		Approved	Nucleoplasm,Centrosome,Cytosol		No	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 72: Non-specific - Transcription"	"Cluster 39: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	"Centrosome, Cytosol"	"HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372"	"unprognostic (1.88e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.44e-2)"	"prognostic unfavorable (5.15e-4)"	"unprognostic (9.81e-2)"	"unprognostic (3.55e-1)"	"unprognostic (3.78e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.65e-1)"	"unprognostic (6.25e-2)"	"unprognostic (1.25e-2)"
MAP2K4	"JNKK1, MEK4, MKK4, PRKMK4, SERK1"	ENSG00000065559	"Mitogen-activated protein kinase kinase 4"	P45985	17	12020829-12143830	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Stress response"	"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 223.6;Inhibitory neurons: 184.9;Oligodendrocyte precursor cells: 142.0;Oligodendrocytes: 191.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 10.4"	"Low lineage specificity"	"Detected in all"			"Cancer enriched"	"Detected in all"	8	"testis cancer: 177.7"		"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB007751, HPA060074"	Enhanced		Approved	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 47: Non-specific - Unknown function"	"Cluster 49: Non-specific - Unknown function"	"Cluster 38: Neurons - Neuronal signaling"	Nucleoplasm	"Cell Junctions"	"CAB007751: , HPA060074: AB_2684197"	"unprognostic (1.55e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.47e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.89e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.93e-3)"	"unprognostic (2.53e-1)"	"unprognostic (2.76e-3)"	"unprognostic (4.82e-2)"	"unprognostic (5.32e-3)"	"unprognostic (3.13e-1)"	"unprognostic (2.30e-1)"	"unprognostic (7.00e-2)"	"unprognostic (1.79e-1)"
MAP3K1	"MAPKKK1, MEKK, MEKK1"	ENSG00000095015	"Mitogen-activated protein kinase kinase kinase 1"	Q13233	5	56815549-56896152	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocyte precursor cells: 201.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Region enriched"	"Detected in all"	6	"olfactory bulb: 18.2"	"Low region specificity"	"Detected in all"			"CAB004500, HPA046509"	Approved		Approved	Cytosol		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 33: Macrophages - Degranulation"	Cytosol		"CAB004500: AB_627926, HPA046509: AB_2679678"	"unprognostic (1.77e-1)"	"unprognostic (1.71e-2)"	"unprognostic (4.09e-1)"	"unprognostic (2.18e-1)"	"unprognostic (3.48e-2)"	"unprognostic (5.39e-3)"	"unprognostic (5.20e-3)"	"unprognostic (2.52e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.05e-2)"	"unprognostic (6.73e-2)"	"unprognostic (1.97e-3)"	"unprognostic (2.18e-2)"	"unprognostic (1.58e-1)"	"unprognostic (9.92e-3)"	"unprognostic (1.11e-1)"
MAX	"bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8"	ENSG00000125952	"MYC associated factor X"	P61244	14	65006174-65102695	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000328, HPA003474"	Supported		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 4: Platelets - Platelet activation"	Nucleoplasm	"Golgi apparatus"	"CAB000328: AB_2281783, HPA003474: AB_1079317"	"unprognostic (4.50e-3)"	"unprognostic (1.51e-3)"	"unprognostic (4.08e-2)"	"unprognostic (2.87e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.30e-3)"	"unprognostic (1.53e-2)"	"unprognostic (7.36e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.66e-2)"	"prognostic unfavorable (5.57e-4)"	"unprognostic (2.99e-1)"	"unprognostic (4.68e-2)"	"prognostic favorable (2.12e-4)"	"unprognostic (6.03e-2)"
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 16: Non-specific - RNA binding"	Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favorable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 5: Non-specific - Unknown function"	"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 84.4"	"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867, CAB080131"	Supported		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , CAB080131: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810063	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 113.3;Theca cells: 92.3"	"Cancer enhanced"	"Detected in all"		"testis cancer: 31.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	Yes		15000	"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 23: B-cell cancers - Adaptive immune response"	"Cluster 17: Granulosa cells - Transcription regulation"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavorable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavorable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"
MTOR	"FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1"	ENSG00000198793	"Mechanistic target of rapamycin kinase"	P42345	1	11106535-11262551	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Biological rhythms"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB069425, CAB080053, CAB080065, CAB080070, CAB080081, CAB080095, CAB080096, CAB080097"	Supported		Supported	"Golgi apparatus,Cytosol"		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 12: Non-specific - Chromatin organization"	"Golgi apparatus, Cytosol"		"CAB069425: , CAB080053: , CAB080065: , CAB080070: , CAB080081: , CAB080095: , CAB080096: , CAB080097: "	"unprognostic (3.18e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.20e-1)"	"unprognostic (2.45e-3)"	"unprognostic (5.50e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.24e-3)"	"unprognostic (3.48e-2)"	"unprognostic (1.88e-1)"	"prognostic favorable (1.49e-5)"	"unprognostic (1.27e-1)"	"unprognostic (2.45e-1)"	"unprognostic (6.60e-2)"	"unprognostic (7.55e-2)"
NBN	"AT-V1, AT-V2, ATV, NBS, NBS1"	ENSG00000104320	Nibrin	O60934	8	89933331-90003228	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"monocytes: 205.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001429, CAB003836, CAB080233"	Supported		Supported	"Nucleoplasm,Mitotic chromosome,Golgi apparatus"		Yes	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm	"Mitotic chromosome, Golgi apparatus"	"CAB003836: AB_562172, CAB080233: , HPA001429: AB_1854460"	"unprognostic (1.52e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.32e-3)"	"unprognostic (7.46e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.05e-2)"	"prognostic unfavorable (5.46e-5)"	"unprognostic (5.05e-2)"	"unprognostic (4.61e-2)"	"prognostic unfavorable (4.20e-4)"	"unprognostic (1.15e-1)"	"unprognostic (6.68e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.28e-1)"	"unprognostic (2.84e-2)"	"unprognostic (1.03e-1)"
NCOR1	"hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1"	ENSG00000141027	"Nuclear receptor corepressor 1"	O75376	17	16029157-16218185	"Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Liver - Hepatocytes"	"Low region specificity"	"Detected in all"							"HPA043246, HPA050288, HPA051168, CAB072830"	Supported		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 6: Brain - Smell perception"	"Cluster 49: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370"	"unprognostic (1.83e-1)"	"unprognostic (3.05e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.10e-1)"	"unprognostic (7.38e-2)"	"unprognostic (3.59e-2)"	"unprognostic (2.55e-2)"	"unprognostic (4.27e-2)"	"unprognostic (4.87e-2)"	"unprognostic (4.06e-2)"	"unprognostic (7.07e-2)"	"unprognostic (1.52e-2)"	"prognostic favorable (7.92e-5)"	"unprognostic (4.40e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.33e-1)"	"unprognostic (5.42e-2)"
NCOR2	"CTG26, SMRT, SMRTE, TNRC14, TRAC-1"	ENSG00000196498	"Nuclear receptor corepressor 2"	Q9Y618	12	124324415-124567589	"Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"basophil: 6.0;non-classical monocyte: 2.5"	"Group enriched"	"Detected in many"	4	"granulocytes: 6.0;monocytes: 2.5"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001928	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 72: Non-specific - Transcription"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 41: Alveolar cells - Lung function"	Nucleoplasm		"HPA001928: AB_1079454"	"unprognostic (9.51e-3)"	"unprognostic (7.37e-3)"	"unprognostic (4.66e-2)"	"unprognostic (2.55e-3)"	"unprognostic (2.14e-1)"	"unprognostic (7.37e-2)"	"unprognostic (3.19e-2)"	"unprognostic (8.86e-2)"	"unprognostic (2.21e-2)"	"unprognostic (2.90e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.96e-1)"	"unprognostic (9.86e-2)"	"unprognostic (6.26e-2)"	"unprognostic (1.59e-1)"	"unprognostic (7.56e-2)"	"unprognostic (8.90e-2)"
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 246.1;Excitatory neurons: 320.6;Inhibitory neurons: 403.2;Oligodendrocyte precursor cells: 410.1;Oligodendrocytes: 299.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria		No	No			"Cluster 20: T-cells - T-cell receptor"	"Cluster 21: Non-specific - Transcription"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 37: Neurons - Neuronal signaling"	Mitochondria		"HPA045502: AB_2679352"	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 69.0;Late spermatids: 122.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 39: Non-specific - Unknown function"	"Cluster 74: Pancreatic cells - Mixed function"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favorable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"
NOTCH2		ENSG00000134250	"Notch receptor 2"	Q04721	1	119911553-120100779	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Differentiation, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"monocytes: 139.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA048743	Approved		Supported	"Nucleoplasm,Plasma membrane"		NA	NA		160000000	"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 28: Placenta - Pregnancy"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 33: Macrophages - Degranulation"	"Nucleoplasm, Plasma membrane"		"HPA048743: AB_2680508"	"unprognostic (1.33e-1)"	"unprognostic (1.43e-2)"	"unprognostic (2.66e-1)"	"unprognostic (1.40e-3)"	"unprognostic (7.98e-2)"	"unprognostic (4.01e-2)"	"unprognostic (1.22e-1)"	"unprognostic (7.32e-2)"	"unprognostic (1.18e-2)"	"prognostic unfavorable (5.24e-4)"	"prognostic unfavorable (9.48e-4)"	"unprognostic (3.86e-2)"	"unprognostic (6.12e-3)"	"unprognostic (1.55e-2)"	"unprognostic (2.65e-2)"	"unprognostic (1.12e-2)"	"unprognostic (7.35e-3)"
PALB2	"FANCN, FLJ21816"	ENSG00000083093	"Partner and localizer of BRCA2"	Q86YC2	16	23603160-23641310	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Spermatocytes: 29.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB014895, HPA057000, HPA059851"	Approved		Supported	"Nucleoplasm,Nuclear speckles"		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 71: Testis - DNA repair"	"Cluster 8: Non-specific - Transcription"	"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis"	"Nucleoplasm, Nuclear speckles"		"CAB014895: , HPA057000: AB_2683307, HPA059851: "	"unprognostic (1.11e-1)"	"unprognostic (5.67e-3)"	"prognostic favorable (2.83e-5)"	"unprognostic (1.43e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.61e-2)"	"unprognostic (2.00e-3)"	"unprognostic (5.18e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.00e-2)"	"prognostic unfavorable (2.35e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.04e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.25e-1)"	"unprognostic (7.20e-2)"	"unprognostic (3.21e-1)"
PBRM1	"BAF180, PB1"	ENSG00000163939	"Polybromo 1"	Q86U86	3	52545352-52685917	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015629, HPA059373"	Uncertain		Enhanced	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 5: Non-specific - Unknown function"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm		"HPA015629: AB_1855012, HPA059373: AB_2683994"	"unprognostic (1.87e-1)"	"unprognostic (1.73e-1)"	"unprognostic (1.91e-2)"	"unprognostic (2.00e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.02e-2)"	"unprognostic (9.54e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.99e-2)"	"unprognostic (4.32e-2)"	"unprognostic (2.89e-3)"	"unprognostic (3.06e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.06e-1)"
PHF6	"BFLS, BORJ, CENP-31, KIAA1823, MGC14797"	ENSG00000156531	"PHD finger protein 6"	Q8IWS0	X	134373312-134428791	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 147.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001023	Enhanced		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 34: Non-specific - Transcription"	"Cluster 48: Non-specific - RNA binding"	"Cluster 17: Granulosa cells - Transcription regulation"	"Nucleoplasm, Nucleoli"		"HPA001023: AB_1079606"	"unprognostic (2.38e-3)"	"unprognostic (8.21e-2)"	"unprognostic (1.99e-1)"	"unprognostic (3.04e-3)"	"unprognostic (6.03e-3)"	"unprognostic (5.20e-3)"	"prognostic unfavorable (3.38e-4)"	"unprognostic (1.81e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.08e-1)"	"prognostic unfavorable (9.96e-4)"	"unprognostic (1.09e-1)"	"unprognostic (5.96e-2)"	"unprognostic (4.84e-2)"	"unprognostic (7.45e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.29e-2)"
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5970925-6009106	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA070310"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 34: Non-specific - Transcription"	"Cluster 63: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB010235: AB_2167281, HPA070310: AB_2686250"	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favorable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"
POT1	"DKFZp586D211, hPot1"	ENSG00000128513	"Protection of telomeres 1"	Q9NUX5	7	124822386-124929983	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Inhibitory neurons: 40.6;Oligodendrocytes: 63.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Skeletal muscle - Endothelial cells, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA068538			Supported	Nucleoplasm		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 31: Non-specific - Transcription"	"Cluster 37: Neurons - Neuronal signaling"	Nucleoplasm		"HPA068538: AB_2686001"	"unprognostic (1.39e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.04e-1)"	"unprognostic (5.71e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-3)"	"unprognostic (7.88e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (2.48e-2)"	"unprognostic (9.89e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.92e-1)"	"unprognostic (1.75e-2)"	"unprognostic (4.77e-3)"	"unprognostic (7.42e-2)"
PPM1D	"PP2C-DELTA, Wip1"	ENSG00000170836	"Protein phosphatase, Mg2+/Mn2+ dependent 1D"	O15297	17	60600183-60666280	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 76.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022277, HPA061848"	Approved		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 66: Endothelial cells - Angiogenesis"	Nucleoplasm	Nucleoli	"HPA022277: AB_1858839, HPA061848: "	"unprognostic (1.48e-1)"	"unprognostic (1.36e-2)"	"prognostic favorable (3.52e-4)"	"unprognostic (1.76e-1)"	"unprognostic (1.02e-1)"	"unprognostic (5.12e-2)"	"prognostic unfavorable (4.27e-4)"	"unprognostic (5.50e-2)"	"unprognostic (1.70e-2)"	"unprognostic (6.07e-2)"	"unprognostic (2.52e-3)"	"unprognostic (3.46e-2)"	"unprognostic (1.95e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.71e-2)"	"unprognostic (1.98e-1)"
PPP6C	PP6	ENSG00000119414	"Protein phosphatase 6 catalytic subunit"	O00743	9	125146573-125189939	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity"	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050940	Uncertain					NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 55: Non-specific - Unknown function"	"Cluster 61: Non-specific - Transcription"			"HPA050940: AB_2681283"	"unprognostic (6.45e-2)"	"unprognostic (4.01e-3)"	"unprognostic (7.12e-2)"	"unprognostic (5.36e-2)"	"unprognostic (2.78e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.57e-3)"	"unprognostic (1.53e-1)"	"unprognostic (2.14e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.71e-2)"	"unprognostic (2.28e-2)"	"prognostic favorable (4.50e-6)"	"unprognostic (1.54e-2)"	"unprognostic (3.51e-1)"	"unprognostic (1.12e-2)"	"unprognostic (1.12e-1)"
PRDM1	"BLIMP1, PRDI-BF1"	ENSG00000057657	"PR/SET domain 1"	O75626	6	105993463-106109939	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation"	"DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"esophagus: 55.2"	"Cell type enhanced"	"Detected in many"		"Langerhans cells: 238.5;NK-cells: 290.6;Plasma cells: 690.4;T-cells: 215.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4"	"Group enriched"	"Detected in many"	5	"granulocytes: 12.5;T-cells: 34.0"	"Cancer enriched"	"Detected in many"	4	"Myeloma: 92.7"	"Colon - T-cells, Prostate - T-cells"	"Region enriched"	"Detected in single"	6	"olfactory bulb: 3.6"	"Low region specificity"	"Detected in many"			"HPA030033, HPA075427"	Approved		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 45: Plasma cells - Humoral immune response"	Nucleoli	Nucleoplasm	"HPA030033: AB_10601050, HPA075427: "	"unprognostic (9.60e-2)"	"unprognostic (3.28e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.98e-2)"	"unprognostic (4.03e-1)"	"unprognostic (3.77e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.81e-1)"	"unprognostic (3.50e-2)"	"unprognostic (7.56e-2)"	"prognostic unfavorable (9.81e-5)"	"unprognostic (1.52e-1)"	"unprognostic (3.51e-1)"	"unprognostic (2.45e-3)"	"unprognostic (7.90e-2)"
PREX2	"DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129"	ENSG00000046889	"Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2"	Q70Z35	8	67952046-68237032	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"		"Guanine-nucleotide releasing factor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 16.1"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 695.3;Microglial cells: 117.7;Oligodendrocyte precursor cells: 404.3;Oligodendrocytes: 209.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"Kidney cancer: 6.8;ovarian cancer: 3.3;Uterine cancer: 4.6"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015234, HPA075956"	Enhanced		Approved	"Endoplasmic reticulum"		NA	NA				"Cluster 57: Non-specific - Angiogenesis"	"Cluster 68: Kidney - Mixed function"	"Cluster 63: Astrocytes - Nervous system maintenance"	"Endoplasmic reticulum"		"HPA015234: AB_1847604, HPA075956: AB_2686769"	"unprognostic (2.25e-1)"	"unprognostic (3.32e-2)"	"unprognostic (1.30e-2)"	"unprognostic (3.39e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.37e-2)"	"unprognostic (4.19e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.98e-2)"	"unprognostic (2.53e-2)"	"unprognostic (8.77e-2)"	"prognostic unfavorable (1.61e-7)"	"unprognostic (8.30e-3)"	"unprognostic (2.79e-1)"	"unprognostic (3.67e-2)"	"unprognostic (6.64e-2)"
PRKACA	PKACa	ENSG00000072062	"Protein kinase cAMP-activated catalytic subunit alpha"	P17612	19	14091688-14118084	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 310.9"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 101.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010361, HPA071185"	Approved		Approved	"Cytokinetic bridge,Cytosol"		Yes	NA		170000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 75: Myeloid cells - Innate immune response"	Cytosol	"Cytokinetic bridge"	"CAB010361: AB_2268772, HPA071185: AB_2686356"	"unprognostic (1.08e-1)"	"prognostic favorable (6.28e-6)"	"unprognostic (2.09e-2)"	"prognostic unfavorable (6.26e-5)"	"unprognostic (1.38e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.64e-1)"	"unprognostic (9.36e-3)"	"unprognostic (7.01e-2)"	"unprognostic (3.41e-1)"	"prognostic favorable (6.47e-4)"	"unprognostic (2.86e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.66e-2)"	"unprognostic (6.14e-3)"
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 776.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol		NA	NA		1800000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 77: Cardiomyocytes - Muscle contraction"	Cytosol		"CAB019378: , HPA049979: AB_2680980"	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 26.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 260.1;Leydig cells: 186.5;Peritubular cells: 426.5;Theca cells: 103.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 6.1"	"Lineage enriched"	"Detected in single"	9	"T-cells: 6.1"	"Low cancer specificity"	"Detected in all"			"Testis - Peritubular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 34: Rabdoid cancer - Embryonic development"	"Cluster 52: Endometrial stromal cells - ECM organization"	"Golgi apparatus"		"CAB013717: , HPA075072: AB_2686733"	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in many"			"Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids"	"Low region specificity"	"Detected in all"							"CAB004076, HPA031335, CAB080153, CAB080155, CAB080157"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 67: Non-specific - Mitochondria & RNA binding"	"Cluster 72: Smooth muscle cells - ECM organization"	Cytosol	Nucleoplasm	"CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"
PTK6	BRK	ENSG00000101213	"Protein tyrosine kinase 6"	Q13882	20	63528001-63537376	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 109.4;skin 1: 53.9;vagina: 43.2"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 114.6;Gastric mucus-secreting cells: 51.3;Intestinal goblet cells: 43.4;Paneth cells: 87.5;Proximal enterocytes: 75.1;Squamous epithelial cells: 56.1;Suprabasal keratinocytes: 82.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in many"			"Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB032952, HPA036070, HPA036071"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol"		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 3: Suprabasal keratinocytes - Cornification"	Nucleoplasm	"Nuclear bodies, Plasma membrane, Cytosol"	"CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982"	"unprognostic (2.32e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.42e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.72e-2)"	"prognostic unfavorable (1.96e-4)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (1.26e-9)"	"unprognostic (4.19e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.73e-1)"	"unprognostic (4.24e-2)"
PTPN13	"PTP-BAS, PTP-BL, PTP1E, PTPL1"	ENSG00000163629	"Protein tyrosine phosphatase non-receptor type 13"	Q12923	4	86594315-86815171	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"retina: 124.3"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 112.1;Astrocytes: 160.1;Cone photoreceptor cells: 137.9;Oligodendrocytes: 189.0;Rod photoreceptor cells: 166.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 2.0"	"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002213, HPA063119"	Approved		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 47: Retina - Visual perception"	"Cluster 22: Squamous epithelial cells - Keratinization"	Nucleoplasm	"Nucleoli fibrillar center, Cytosol"	"CAB002213: AB_564089, HPA063119: "	"unprognostic (5.36e-2)"	"unprognostic (4.46e-1)"	"unprognostic (1.11e-1)"	"unprognostic (2.54e-3)"	"unprognostic (4.02e-1)"	"unprognostic (9.03e-3)"	"unprognostic (4.43e-2)"	"unprognostic (4.38e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.05e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.28e-3)"	"unprognostic (3.95e-3)"	"unprognostic (2.26e-1)"	"unprognostic (2.66e-1)"	"unprognostic (2.85e-2)"
PTPRB	PTPB	ENSG00000127329	"Protein tyrosine phosphatase receptor type B"	P23467	12	70515870-70637440	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Angiogenesis	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 208.8;Endothelial cells: 225.2;Inhibitory neurons: 67.1;Microglial cells: 160.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"prostate cancer: 11.8"	"Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004782, HPA067868"	Uncertain		Approved	"Vesicles,Plasma membrane,Cell Junctions"		NA	NA		14000000	"Cluster 43: B-cells - Humoral immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 66: Endothelial cells - Angiogenesis"	"Plasma membrane"	"Vesicles, Cell Junctions"	"CAB004782: , HPA067868: AB_2685911"	"unprognostic (3.18e-1)"	"unprognostic (2.99e-6)"	"unprognostic (1.56e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.55e-2)"	"unprognostic (1.77e-2)"	"prognostic favorable (6.05e-4)"	"unprognostic (4.59e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.40e-1)"	"prognostic favorable (1.02e-4)"	"unprognostic (2.91e-2)"	"unprognostic (7.18e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.38e-1)"
PTPRC	"CD45, GP180, LCA, T200"	ENSG00000081237	"Protein tyrosine phosphatase receptor type C"	P08575	1	198638457-198757476	"Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"Hydrolase, Protein phosphatase"	"Cancer-related genes, Disease variant, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 208.6;lymphoid tissue: 329.9"	"Cell type enhanced"	"Detected in many"		"B-cells: 506.7;Kupffer cells: 464.5;Macrophages: 507.9;monocytes: 1400.2;NK-cells: 1356.4;T-cells: 1034.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in many"	7	"Leukemia: 117.5;lymphoma: 158.9"	"Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Skin - T-cells, Thyroid - T-cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000052, HPA000440, CAB002800, CAB056154, CAB068221"	Enhanced		Uncertain	Nucleoplasm,Vesicles	"Intracellular and membrane"	NA	NA		24000000	"Cluster 14: Monocytes - Unknown function"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 1: T-cells - Immune response"	"Nucleoplasm, Vesicles"		"CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-2)"	"unprognostic (5.10e-3)"	"unprognostic (2.33e-3)"	"unprognostic (1.30e-1)"	"unprognostic (2.40e-3)"	"unprognostic (1.62e-1)"	"unprognostic (3.17e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.18e-2)"	"unprognostic (8.08e-2)"	"unprognostic (3.95e-1)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (2.31e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.41e-2)"	"unprognostic (7.06e-2)"
PTPRT	"KIAA0283, RPTPrho"	ENSG00000196090	"Protein tyrosine phosphatase receptor type T"	O14522	20	42072752-43189970	"Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins"		"Hydrolase, Protein phosphatase, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 23.9;fallopian tube: 10.8"	"Group enriched"	"Detected in some"	15	"Excitatory neurons: 493.6;Inhibitory neurons: 681.2;Oligodendrocyte precursor cells: 401.0"	"Group enriched"	"Detected in many"	5	"breast cancer: 5.1;prostate cancer: 1.9"	"Region enhanced"	"Detected in many"		"cerebral cortex: 23.9"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"lymphoma: 1.1;Sarcoma: 2.3"	"Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017336, CAB069423"	Approved					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 56: Neurons - Neuronal signaling"	"Cluster 32: Neurons - Synaptic function"			"CAB069423: AB_1622602, HPA017336: AB_1855943"	"unprognostic (7.17e-3)"	"unprognostic (1.02e-1)"	"unprognostic (5.61e-3)"	"unprognostic (1.08e-2)"	"unprognostic (5.95e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.31e-2)"	"unprognostic (6.93e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.37e-6)"	"unprognostic (3.16e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.17e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.17e-1)"
RAD21	"hHR21, KIAA0078, SCC1"	ENSG00000164754	"RAD21 cohesin complex component"	O60216	8	116845934-116874776	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 464.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA020044, CAB022065, HPA073277"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 34: Non-specific - Transcription"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 6: Late spermatids - Spermatogenesis"	Nucleoplasm		"CAB022065: , HPA020044: AB_1856035, HPA073277: "	"unprognostic (7.85e-2)"	"unprognostic (4.92e-1)"	"unprognostic (3.05e-1)"	"unprognostic (5.43e-3)"	"unprognostic (9.56e-2)"	"unprognostic (3.50e-1)"	"prognostic unfavorable (1.71e-4)"	"unprognostic (1.86e-3)"	"unprognostic (8.99e-2)"	"unprognostic (8.80e-2)"	"unprognostic (5.58e-3)"	"unprognostic (3.56e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.95e-1)"
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303744-48599436	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 252.8;Melanocytes: 282.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 13: Non-specific - Nuclear processes"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008"	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"
RBM10	"DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5"	ENSG00000182872	"RNA binding motif protein 10"	P98175	X	47145221-47186813	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034972, HPA057372"	Approved		Enhanced	"Nuclear speckles"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 35: Non-specific - Unknown function"	"Cluster 48: Non-specific - RNA binding"	"Cluster 16: Non-specific - RNA binding"	"Nuclear speckles"		"HPA034972: AB_10602919, HPA057372: AB_2683421"	"unprognostic (9.07e-2)"	"prognostic favorable (6.71e-4)"	"unprognostic (7.83e-2)"	"unprognostic (1.61e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.04e-2)"	"unprognostic (4.47e-3)"	"unprognostic (8.11e-2)"	"unprognostic (9.86e-3)"	"unprognostic (1.76e-1)"	"prognostic favorable (2.86e-6)"	"unprognostic (1.18e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.33e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.40e-2)"	"unprognostic (1.20e-3)"
RECQL4	RecQ4	ENSG00000160957	"RecQ like helicase 4"	O94761	8	144511288-144517845	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Helicase, Hydrolase"	"Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 25.4;testis: 22.4"	"Cell type enhanced"	"Detected in many"		"Plasma cells: 11.3;Spermatocytes: 23.9;Spermatogonia: 16.8;Undifferentiated cells: 15.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach)"	"Low region specificity"	"Detected in single"							"CAB017800, HPA025821"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 32: T-cells - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 43: Non-specific - Cell proliferation"	Nucleoplasm		"CAB017800: , HPA025821: AB_1856168"	"unprognostic (5.92e-2)"	"unprognostic (1.86e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.17e-2)"	"unprognostic (3.17e-2)"	"prognostic unfavorable (1.91e-4)"	"unprognostic (1.12e-2)"	"unprognostic (4.12e-2)"	"unprognostic (7.53e-2)"	"unprognostic (2.65e-2)"	"unprognostic (4.26e-2)"	"unprognostic (1.12e-3)"	"unprognostic (8.82e-3)"	"unprognostic (1.74e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.34e-1)"
RET	"CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51"	ENSG00000165731	"Ret proto-oncogene"	P07949	10	43077064-43130351	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8"	"Group enriched"	"Detected in some"	4	"dendritic cells: 48.0;Horizontal cells: 28.8"	"Cancer enhanced"	"Detected in many"		"breast cancer: 11.0"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	7	"Neuroblastoma: 120.9;thyroid cancer: 39.8"	"Colon - Colon enteroendocrine cells, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"midbrain: 53.3;spinal cord: 19.4"	"CAB002581, HPA008356, HPA008495"	Approved	Supported	Approved	"Golgi apparatus,Plasma membrane,Cytosol"		No	NA		2100000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction"	"Cluster 65: Fibroblasts - ECM organization"	"Golgi apparatus, Cytosol"	"Plasma membrane"	"CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: "	"unprognostic (7.94e-2)"	"unprognostic (3.68e-2)"	"unprognostic (4.49e-1)"	"prognostic unfavorable (5.02e-4)"	"unprognostic (1.15e-1)"	"unprognostic (9.13e-4)"	"unprognostic (1.27e-2)"	"unprognostic (3.62e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.54e-3)"	"unprognostic (4.43e-1)"	"unprognostic (9.35e-5)"	"unprognostic (1.64e-3)"	"unprognostic (8.28e-2)"	"unprognostic (3.67e-3)"	"unprognostic (2.02e-2)"
RNF43	"DKFZp781H0392, FLJ20315, URCC"	ENSG00000108375	"Ring finger protein 43"	Q68DV7	17	58353676-58417595	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"	"Ubl conjugation pathway, Wnt signaling pathway"	"Developmental protein, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 22.7"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 28.2;Intestinal goblet cells: 23.4;Undifferentiated cells: 33.6"	"Cancer enriched"	"Detected in many"	4	"colorectal cancer: 41.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"Bile duct cancer: 44.6;colorectal cancer: 72.4;Gastric cancer: 38.7"	"Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells"									HPA008079	Uncertain					NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 19: Stomach & Colon cancer - Absorption"	"Cluster 26: Intestinal epithelial cells - Absorption"			"HPA008079: AB_1856371"	"unprognostic (2.53e-1)"	"unprognostic (1.09e-1)"	"unprognostic (7.46e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.33e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.62e-1)"	"unprognostic (2.93e-1)"	"unprognostic (1.05e-1)"	"unprognostic (5.69e-2)"	"unprognostic (3.79e-1)"	"prognostic favorable (6.04e-9)"	"unprognostic (3.61e-3)"	"unprognostic (2.56e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.04e-2)"
RPL5	"L5, PPP1R135, uL18"	ENSG00000122406	"Ribosomal protein L5"	P46777	1	92832013-92841924	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins"		"Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding"	"Cancer-related genes, Diamond-Blackfan anemia, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"												"HPA043717, HPA054444"	Approved		Supported	"Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol"		NA	NA		430000	"Cluster 30: Non-specific - Translation"	"Cluster 50: Non-specific - Ribosome"	"Cluster 57: Non-specific - Translation"	"Cluster 39: Non-specific - Translation"	"Endoplasmic reticulum, Cytosol"	"Nucleoli, Nucleoli rim"	"HPA043717: AB_10964719, HPA054444: AB_2732584"	"unprognostic (5.81e-3)"	"unprognostic (3.96e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.52e-1)"	"unprognostic (9.44e-3)"	"unprognostic (1.96e-1)"	"unprognostic (1.03e-3)"	"unprognostic (9.95e-2)"	"unprognostic (8.68e-2)"	"unprognostic (1.23e-1)"	"unprognostic (3.98e-2)"	"unprognostic (3.48e-1)"	"prognostic unfavorable (6.81e-5)"	"unprognostic (2.26e-2)"	"unprognostic (3.12e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.97e-1)"
SBDS	"CGI-97, FLJ10917, SDS, SWDS"	ENSG00000126524	"SBDS ribosome maturation factor"	Q9Y3A5	7	66987680-66995587	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ribosome biogenesis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in all"	4	"Late spermatids: 2157.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028891	Approved		Supported	Nucleoplasm,Cytosol		NA	NA		190000	"Cluster 44: Non-specific - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 31: Non-specific - Transcription"	"Cluster 51: Late spermatids - Spermatogenesis"	"Nucleoplasm, Cytosol"		"HPA028891: AB_10601500"	"prognostic unfavorable (1.49e-4)"	"unprognostic (1.87e-2)"	"unprognostic (5.73e-2)"	"unprognostic (1.71e-3)"	"unprognostic (8.06e-3)"	"prognostic unfavorable (3.65e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.44e-1)"	"unprognostic (6.99e-2)"	"unprognostic (7.84e-3)"	"unprognostic (4.59e-1)"	"unprognostic (1.04e-2)"	"unprognostic (9.38e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.30e-1)"	"unprognostic (5.06e-3)"
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-257082	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 601.0;skeletal muscle: 479.0"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 459.4;Proximal enterocytes: 261.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes"									"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria		No	No		360000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Enzymes"	"Cluster 77: Cardiomyocytes - Muscle contraction"	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavorable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favorable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054032	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Electron transport, Host-virus interaction, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 491.5;tongue: 580.6"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 581.2;Proximal tubular cells: 395.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"	NA	NA		7900	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 18: Non-specific - Mixed function"	Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favorable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"
SDHC	"CYB560, cybL, PGL3"	ENSG00000143252	"Succinate dehydrogenase complex subunit C"	Q99643	1	161314381-161363206	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 538.0;Proximal tubular cells: 804.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: Non-specific - RNA binding"	"Cluster 60: Proximal tubular cells - Absorption"				"unprognostic (1.48e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.02e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.33e-1)"	"unprognostic (7.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-2)"	"unprognostic (1.29e-1)"	"prognostic favorable (2.20e-4)"	"unprognostic (9.14e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.19e-3)"	"unprognostic (3.77e-1)"
SDHD	"cybS, PGL, PGL1"	ENSG00000204370	"Succinate dehydrogenase complex subunit D"	O14521	11	112086824-112120016	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 391.6;Distal tubular cells: 429.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells"					"Low region specificity"	"Detected in all"			HPA045727	Approved				"Intracellular and membrane"	NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 58: Non-specific - Basic cellular processes"	"Cluster 77: Cardiomyocytes - Muscle contraction"			"HPA045727: AB_10963114"	"unprognostic (9.13e-2)"	"unprognostic (3.51e-2)"	"unprognostic (4.47e-3)"	"unprognostic (4.21e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.98e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.83e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.80e-1)"	"prognostic favorable (1.99e-10)"	"unprognostic (5.14e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.56e-2)"	"unprognostic (7.51e-2)"
SETD2	"FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A"	ENSG00000181555	"SET domain containing 2, histone lysine methyltransferase"	Q9BYW2	3	47016429-47164113	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042451	Approved		Approved	"Nuclear speckles,Cytosol"		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 34: Non-specific - Transcription"	"Cluster 5: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	"Nuclear speckles"	Cytosol	"HPA042451: AB_10806239"	"unprognostic (2.78e-1)"	"unprognostic (1.01e-1)"	"unprognostic (6.08e-2)"	"unprognostic (1.01e-1)"	"unprognostic (3.37e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.01e-2)"	"prognostic unfavorable (8.19e-4)"	"unprognostic (6.19e-2)"	"unprognostic (2.45e-1)"	"unprognostic (7.84e-2)"	"prognostic favorable (7.99e-6)"	"unprognostic (1.03e-1)"	"unprognostic (1.91e-1)"	"unprognostic (8.79e-2)"	"unprognostic (5.43e-2)"
SH2B3	"IDDM20, LNK"	ENSG00000111252	"SH2B adaptor protein 3"	Q9UQQ2	12	111405923-111451623	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Diabetes mellitus"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 60.7"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 216.4;Kupffer cells: 84.7;Langerhans cells: 142.9;Macrophages: 95.1;monocytes: 124.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005483	Approved		Approved	Nucleoplasm		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 3: HUVEC & TIME - Signal transduction"	"Cluster 48: Plasmacytoid dendritic cells - Unknown function"	Nucleoplasm		"HPA005483: AB_1079260"	"unprognostic (2.77e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.20e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.09e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.18e-1)"	"unprognostic (4.65e-2)"	"unprognostic (8.17e-3)"	"unprognostic (9.08e-2)"	"prognostic unfavorable (6.20e-4)"	"unprognostic (2.86e-1)"	"unprognostic (3.89e-3)"	"unprognostic (1.11e-1)"	"unprognostic (2.24e-2)"
SMAD2	"JV18-1, MADH2, MADR2"	ENSG00000175387	"SMAD family member 2"	Q15796	18	47808957-47931146	"Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025507, HPA067203, CAB073546"	Approved		Supported	Nucleoplasm,Nucleoli,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 34: Non-specific - Transcription"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 6: Late spermatids - Spermatogenesis"	"Nucleoplasm, Nucleoli, Cytosol"		"CAB025507: , CAB073546: , HPA067203: AB_2685803"	"unprognostic (1.55e-1)"	"unprognostic (2.49e-1)"	"unprognostic (1.43e-2)"	"unprognostic (9.82e-3)"	"unprognostic (9.88e-2)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (9.44e-5)"	"unprognostic (1.91e-2)"	"unprognostic (7.59e-2)"	"unprognostic (1.41e-3)"	"unprognostic (6.46e-2)"	"unprognostic (4.91e-2)"	"unprognostic (9.20e-3)"	"unprognostic (2.68e-1)"	"unprognostic (6.13e-2)"	"unprognostic (3.20e-2)"	"unprognostic (6.28e-2)"
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 130.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019154, CAB080136"	Approved		Supported	Nucleoplasm,Centrosome,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 41: Non-specific - Cilium assembly"	"Cluster 17: Granulosa cells - Transcription regulation"	"Nucleoplasm, Cytosol"	Centrosome	"CAB080136: , HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favorable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"
SMARCA4	"BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2"	ENSG00000127616	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4"	P51532	19	10960932-11079426	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004208, HPA048340"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 18: Non-specific - Mixed function"	"Nucleoplasm, Nucleoli fibrillar center, Nucleoli rim"		"CAB004208: AB_626762, HPA048340: "	"unprognostic (2.68e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.43e-3)"	"unprognostic (1.40e-1)"	"unprognostic (6.33e-3)"	"prognostic unfavorable (1.11e-4)"	"unprognostic (7.19e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.80e-3)"	"unprognostic (6.83e-3)"	"unprognostic (5.44e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838009	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 253.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"Myeloma: 21.4"	"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 44: Myeloma - Humoral immune response"	"Cluster 62: B-cells - B-cell activation"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favorable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"
SMARCD1	"BAF60A, CRACD1, Rsc6p"	ENSG00000066117	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1"	Q96GM5	12	50085200-50100707	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	Neurogenesis	"Chromatin regulator"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA004101	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	Vesicles	"HPA004101: AB_1080026"	"unprognostic (1.88e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.11e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.76e-1)"	"prognostic unfavorable (2.53e-8)"	"unprognostic (3.62e-2)"	"unprognostic (1.44e-1)"	"unprognostic (4.23e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.10e-2)"	"unprognostic (1.20e-3)"	"unprognostic (2.18e-1)"	"unprognostic (3.45e-1)"	"unprognostic (1.38e-1)"	"unprognostic (5.04e-2)"
SMARCE1	BAF57	ENSG00000073584	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1"	Q969G3	17	40624962-40648654	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	Neurogenesis	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003916, CAB037318"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 34: Non-specific - Transcription"	"Cluster 65: Breast cancer - Unknown function"	"Cluster 61: Non-specific - Transcription"	Nucleoplasm		"CAB037318: AB_476780, HPA003916: AB_1857279"	"unprognostic (7.91e-2)"	"unprognostic (2.68e-2)"	"unprognostic (2.09e-2)"	"unprognostic (8.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.55e-2)"	"unprognostic (4.48e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-2)"	"unprognostic (2.04e-1)"	"unprognostic (9.80e-2)"	"unprognostic (5.93e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.27e-2)"
SPEN	"KIAA0929, MINT, RBM15C, SHARP"	ENSG00000065526	"Spen family transcriptional repressor"	Q96T58	1	15836095-15940456	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor, RNA-binding"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015825, HPA050257"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 38: Non-specific - mRNA processing"	"Cluster 14: Endometrium - Transcription regulation"	Nucleoplasm		"HPA015825: AB_1856823, HPA050257: AB_2681065"	"unprognostic (3.91e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.76e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.48e-1)"	"unprognostic (3.06e-2)"	"unprognostic (6.93e-3)"	"unprognostic (2.26e-1)"	"unprognostic (4.26e-2)"	"unprognostic (4.88e-3)"	"unprognostic (1.71e-1)"	"unprognostic (5.98e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.49e-1)"	"unprognostic (1.66e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.83e-1)"
SRC	"ASV, c-src, SRC1"	ENSG00000197122	"SRC proto-oncogene, non-receptor tyrosine kinase"	P12931	20	37344685-37406050	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters"	"Cell adhesion, Cell cycle, Host-virus interaction, Immunity"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Gastric mucus-secreting cells: 42.3;Langerhans cells: 55.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"intermediate monocyte: 2.4;non-classical monocyte: 2.3"	"Group enriched"	"Detected in many"	6	"dendritic cells: 1.4;monocytes: 2.4"	"Low cancer specificity"	"Detected in all"			"Testis - Sertoli cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004023, HPA030875"	Approved		Supported	"Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol"		NA	NA		3200000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 71: Testis - DNA repair"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 26: Intestinal epithelial cells - Absorption"	"Plasma membrane, Cell Junctions"	"Nucleoplasm, Cytosol"	"CAB004023: AB_2106059, HPA030875: AB_2673640"	"unprognostic (5.58e-2)"	"unprognostic (9.83e-2)"	"unprognostic (3.56e-1)"	"unprognostic (4.54e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.54e-2)"	"prognostic unfavorable (4.90e-5)"	"unprognostic (3.89e-2)"	"unprognostic (7.04e-2)"	"unprognostic (8.13e-2)"	"unprognostic (1.54e-2)"	"prognostic unfavorable (1.63e-4)"	"prognostic unfavorable (1.22e-4)"	"unprognostic (2.33e-2)"	"unprognostic (4.72e-2)"	"unprognostic (3.65e-2)"	"prognostic favorable (5.22e-5)"
STAG2	"SA-2, SA2, SCC3B"	ENSG00000101972	"Stromal antigen 2"	Q8N3U4	X	123960212-124422664	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis"		"Cancer-related genes, Disease variant, Holoprosencephaly"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002857	Supported		Supported	"Nucleoplasm,Nucleoli,Nucleoli fibrillar center"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 48: Non-specific - RNA binding"	"Cluster 64: Non-specific - Transcription"	"Nucleoplasm, Nucleoli, Nucleoli fibrillar center"		"HPA002857: AB_1079861"	"unprognostic (1.62e-1)"	"unprognostic (1.01e-2)"	"unprognostic (6.75e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.37e-2)"	"unprognostic (2.70e-2)"	"unprognostic (3.77e-2)"	"unprognostic (9.67e-3)"	"unprognostic (4.68e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.24e-1)"	"unprognostic (3.38e-1)"	"unprognostic (1.59e-3)"	"unprognostic (2.81e-1)"	"unprognostic (2.77e-2)"	"unprognostic (1.63e-1)"	"unprognostic (3.97e-1)"
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228431	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 152.3;Late spermatids: 360.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 9.9"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 59: Non-specific - Translation"	"Cluster 53: Non-specific - mRNA processing"	"Cluster 51: Late spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847"	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favorable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favorable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"
TBX3	"TBX3-ISO, UMS, XHL"	ENSG00000135111	"T-box transcription factor 3"	O15119	12	114670255-114684175	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adrenal gland: 178.4"	"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 393.8;Endometrial stromal cells: 144.0;Prostatic glandular cells: 225.2;Syncytiotrophoblasts: 658.1"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 49.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 79.7;prostate cancer: 68.4"	"Breast - Breast glandular cells, Skin - Eccrine sweat gland cells"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA005799, HPA075876"			Supported	Nucleoplasm,Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 21: Neuroblastoma - Neuronal signaling"	"Cluster 70: Basal prostatic cells - Lipid metabolism"	Nucleoplasm	Cytosol	"HPA005799: AB_1857817, HPA075876: "	"unprognostic (3.27e-1)"	"unprognostic (2.64e-1)"	"unprognostic (2.84e-1)"	"unprognostic (1.11e-1)"	"unprognostic (3.40e-2)"	"unprognostic (5.97e-3)"	"unprognostic (1.56e-1)"	"unprognostic (2.99e-2)"	"unprognostic (9.43e-2)"	"unprognostic (1.15e-1)"	"unprognostic (3.35e-1)"	"unprognostic (3.06e-1)"	"unprognostic (3.64e-3)"	"unprognostic (1.09e-3)"	"unprognostic (1.43e-1)"	"unprognostic (1.01e-1)"	"prognostic favorable (3.28e-4)"
TET2	"FLJ20032, KIAA1546"	ENSG00000168769	"Tet methylcytosine dioxygenase 2"	Q6N021	4	105145875-105279816	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"monocytes: 183.0;Oligodendrocytes: 121.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 55.5"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 55.5"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA043135	Supported		Approved	Nucleoplasm		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm		"HPA043135: AB_10794177"	"unprognostic (6.83e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.69e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.15e-2)"	"unprognostic (5.88e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.19e-3)"	"unprognostic (1.15e-2)"	"unprognostic (1.57e-2)"	"unprognostic (5.77e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.70e-3)"	"unprognostic (6.10e-2)"	"unprognostic (1.89e-1)"	"unprognostic (9.15e-2)"	"unprognostic (7.84e-2)"
TGFBR2	"MFS2, TBR-ii, TBRII"	ENSG00000163513	"Transforming growth factor beta receptor 2"	P37173	3	30606601-30694142	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins"	"Apoptosis, Differentiation, Growth regulation"	"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 394.6;Alveolar cells type 1: 203.2;Endothelial cells: 391.4;Fibroblasts: 211.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB073537			Supported	"Plasma membrane"		NA	NA		810000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 59: Fibroblasts - Metabolism"	"Cluster 66: Endothelial cells - Angiogenesis"	"Plasma membrane"		"CAB073537: "	"unprognostic (1.74e-1)"	"unprognostic (1.84e-2)"	"unprognostic (3.70e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.62e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.65e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.81e-2)"	"unprognostic (8.81e-2)"	"unprognostic (8.02e-2)"
TMEM127	"FLJ20507, FLJ22257"	ENSG00000135956	"Transmembrane protein 127"	O75204	2	96248514-96265997	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins"			"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 69: Macrophages - Innate immune response"				"unprognostic (5.15e-3)"	"unprognostic (2.67e-1)"	"unprognostic (1.72e-2)"	"unprognostic (6.51e-2)"	"unprognostic (5.82e-2)"	"unprognostic (2.05e-1)"	"prognostic unfavorable (6.59e-4)"	"unprognostic (6.73e-2)"	"unprognostic (4.25e-1)"	"unprognostic (1.06e-2)"	"unprognostic (7.50e-2)"	"unprognostic (2.17e-1)"	"prognostic favorable (6.69e-5)"	"unprognostic (3.59e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.15e-2)"	"unprognostic (3.65e-2)"
TNFAIP3	"A20, OTUD7C"	ENSG00000118503	"TNF alpha induced protein 3"	P21580	6	137867214-137883312	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Inflammatory response, Ubl conjugation pathway"	"DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 519.5"	"Cell type enhanced"	"Detected in many"		"Glandular and luminal cells: 1484.6;granulocytes: 1660.0;monocytes: 885.5;T-cells: 735.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"Myeloma: 95.2"	"Pancreas - Ductal cells, Thyroid - T-cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002116	Approved		Approved	Centrosome,Cytosol		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 12: Lymphoid cancers - Adaptive immune response"	"Cluster 75: Myeloid cells - Innate immune response"	"Centrosome, Cytosol"		"HPA002116: AB_1858162"	"unprognostic (5.50e-3)"	"unprognostic (9.98e-3)"	"unprognostic (3.06e-2)"	"unprognostic (1.01e-2)"	"unprognostic (4.01e-2)"	"unprognostic (9.47e-2)"	"unprognostic (5.01e-3)"	"unprognostic (4.40e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.06e-1)"	"prognostic unfavorable (6.05e-4)"	"unprognostic (6.06e-2)"	"unprognostic (3.55e-3)"	"unprognostic (1.27e-1)"	"unprognostic (6.29e-2)"
TNFRSF14	"ATAR, CD270, HVEA, HVEM, LIGHTR, TR2"	ENSG00000157873	"TNF receptor superfamily member 14"	Q92956	1	2555639-2565382	"Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Adaptive immunity, Host-virus interaction, Immunity, Innate immunity"	"Host cell receptor for virus entry, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Proximal enterocytes: 213.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cancer enhanced"	"Detected in many"		"skin cancer: 17.7"		"Low region specificity"	"Detected in all"							"HPA006404, CAB026150, CAB030007"	Approved					NA	NA		110000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 64: Macrophages - Immune response"	"Cluster 16: Skin cancer - Melanocyte processes"	"Cluster 59: Proximal enterocytes - Transmembrane transport"			"CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348"	"prognostic favorable (4.39e-5)"	"unprognostic (3.48e-2)"	"unprognostic (1.53e-2)"	"prognostic favorable (8.01e-6)"	"unprognostic (1.11e-2)"	"unprognostic (6.83e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.32e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.31e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.72e-2)"	"unprognostic (1.58e-1)"	"prognostic favorable (7.79e-6)"
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876"	Enhanced		Enhanced	Nucleoplasm,Vesicles,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 49: Non-specific - Unknown function"	"Cluster 39: Non-specific - Translation"	Nucleoplasm	"Vesicles, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"
TP63	"EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L"	ENSG00000073282	"Tumor protein p63"	Q9H3D4	3	189631389-189897276	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 69.6;skin 1: 137.3"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 202.3;Basal squamous epithelial cells: 251.1;Skeletal myocytes: 81.2;Squamous epithelial cells: 157.7;Suprabasal keratinocytes: 189.8"	"Group enriched"	"Detected in many"	11	"cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Esophageal cancer: 110.8;Gallbladder cancer: 189.5;head and neck cancer: 118.7"	"Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000083, HPA006288, HPA006289, HPA007009, HPA007010"	Enhanced		Enhanced	Nucleoplasm		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 60: Keratinocytes - Epithelial cell function"	"Cluster 22: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336"	"prognostic favorable (1.07e-4)"	"unprognostic (1.30e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.02e-1)"	"unprognostic (4.38e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.78e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.09e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.87e-5)"	"unprognostic (1.86e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.74e-3)"
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in all"	4	"Late spermatids: 412.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 55: Non-specific - Unknown function"	"Cluster 6: Late spermatids - Spermatogenesis"	Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666"	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favorable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favorable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047967-2089491	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Basal prostatic cells: 144.6;Horizontal cells: 126.3;Rod photoreceptor cells: 161.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 8: Non-specific - Transcription"	"Cluster 70: Basal prostatic cells - Lipid metabolism"	Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848"	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favorable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"
UBR5	"DD5, EDD, EDD1, HYD, KIAA0896"	ENSG00000104517	"Ubiquitin protein ligase E3 component n-recognin 5"	O95071	8	102252273-102412759	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 232.5;Excitatory neurons: 211.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA053688			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 12: Non-specific - Chromatin organization"	Nucleoplasm	Cytosol	"HPA053688: AB_2682230"	"unprognostic (3.79e-3)"	"unprognostic (7.44e-3)"	"unprognostic (1.25e-1)"	"unprognostic (2.10e-2)"	"unprognostic (2.44e-2)"	"unprognostic (1.41e-1)"	"prognostic unfavorable (1.26e-4)"	"unprognostic (2.50e-1)"	"unprognostic (1.75e-2)"	"unprognostic (7.54e-3)"	"unprognostic (8.29e-3)"	"unprognostic (3.84e-2)"	"unprognostic (6.64e-2)"	"unprognostic (3.16e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.45e-1)"
USP8	"HumORF8, KIAA0055, SPG59, UBPY"	ENSG00000138592	"Ubiquitin specific peptidase 8"	P40818	15	50424380-50514421	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Ubl conjugation pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050215	Approved		Supported	"Golgi apparatus,Cytosol"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 45: Non-specific - Cell proliferation"	"Cluster 64: Non-specific - Transcription"	"Golgi apparatus"	Cytosol	"HPA050215: AB_2681054"	"unprognostic (5.81e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.46e-1)"	"unprognostic (9.58e-2)"	"unprognostic (2.35e-2)"	"unprognostic (2.91e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.96e-1)"	"unprognostic (1.68e-2)"	"unprognostic (5.08e-2)"	"unprognostic (2.94e-1)"	"unprognostic (3.99e-2)"	"prognostic favorable (1.29e-5)"	"unprognostic (4.89e-2)"	"unprognostic (1.13e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.58e-1)"
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141778-10153667	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031631, HPA031632, HPA068954"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 5: Non-specific - Unknown function"	"Cluster 75: Myeloid cells - Innate immune response"	Nucleoplasm	Cytosol	"HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: "	"prognostic unfavorable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favorable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"
WAS	"IMD2, THC, WASP, WASPA"	ENSG00000015285	"WASP actin nucleation promoting factor"	P42768	X	48676596-48691427	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 58.4;lymphoid tissue: 83.0"	"Cell type enhanced"	"Detected in many"		"B-cells: 86.4;dendritic cells: 66.9;Hofbauer cells: 142.9;Kupffer cells: 133.6;Macrophages: 108.5;monocytes: 203.6;NK-cells: 98.3;T-cells: 98.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 37.4"	"Group enriched"	"Detected in all"	4	"granulocytes: 37.4;monocytes: 9.5"	"Group enriched"	"Detected in many"	37	"Leukemia: 64.4;lymphoma: 65.1;Myeloma: 43.1"	"Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002022, CAB004290"	Enhanced		Approved	"Plasma membrane,Cytosol"		NA	NA		600000	"Cluster 52: Eosinophils - Transcription"	"Cluster 2: Immune cells - Immune response"	"Cluster 62: Granulocytes - Innate immune response"	"Cluster 33: Macrophages - Degranulation"	"Plasma membrane"	Cytosol	"CAB004290: AB_628445, HPA002022: AB_1080581"	"unprognostic (1.43e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.36e-2)"	"prognostic favorable (4.95e-4)"	"unprognostic (9.89e-2)"	"prognostic favorable (3.78e-4)"	"unprognostic (5.12e-3)"	"unprognostic (7.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.40e-2)"	"unprognostic (3.60e-1)"	"prognostic unfavorable (5.58e-6)"	"unprognostic (2.24e-1)"	"unprognostic (2.37e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.71e-1)"
WRN	"RECQ3, RECQL2"	ENSG00000165392	"WRN RecQ like helicase"	Q14191	8	31033788-31176138	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 150.9;Oligodendrocytes: 83.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA009423, HPA028661"	Approved		Enhanced	"Nuclear speckles"		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 49: Early spermatids - Spermatogenesis"	"Nuclear speckles"		"HPA009423: , HPA028661: AB_10602255"	"unprognostic (8.73e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.51e-3)"	"unprognostic (3.85e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.27e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.53e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.00e-2)"	"unprognostic (2.66e-1)"
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"WT1 transcription factor"	P19544	11	32387775-32435564	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8"	"Cell type enhanced"	"Detected in some"		"Collecting duct cells: 29.5;Endometrial stromal cells: 81.6;Sertoli cells: 135.4;Thymic epithelial cells: 80.7"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Leukemia: 10.0"	"Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Sertoli cells"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm,Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 10: Ovarian & Endometrial cancers - Unknown function"	"Cluster 52: Endometrial stromal cells - ECM organization"	Nucleoplasm	Cytosol	"CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279"	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"
XPA	"XP1, XPAC"	ENSG00000136936	"XPA, DNA damage recognition and repair factor"	P23025	9	97674909-97697340	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000155, HPA056856"	Supported		Approved	"Nucleoplasm,Cytokinetic bridge"		Yes	No			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 55: Non-specific - Unknown function"	"Cluster 68: Muller glia cells - Visual perception"	Nucleoplasm	"Cytokinetic bridge"	"CAB000155: , HPA056856: AB_2683258"	"unprognostic (8.76e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.60e-1)"	"unprognostic (2.30e-2)"	"unprognostic (4.17e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.26e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.97e-3)"	"unprognostic (9.55e-3)"	"prognostic favorable (4.28e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.56e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.17e-1)"
XPC	"RAD4, XPCC"	ENSG00000154767	"XPC complex subunit, DNA damage recognition and repair factor"	Q01831	3	14145147-14178621	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009932, HPA035707, HPA069673"	Supported		Enhanced	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 72: Non-specific - Transcription"	"Cluster 5: Non-specific - Unknown function"	"Cluster 64: Non-specific - Transcription"	Nucleoplasm	"Plasma membrane"	"CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167"	"unprognostic (7.46e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.50e-2)"	"unprognostic (3.01e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.54e-2)"	"unprognostic (1.97e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.50e-1)"	"unprognostic (7.13e-3)"	"unprognostic (4.39e-2)"	"unprognostic (2.07e-1)"	"prognostic favorable (4.14e-7)"	"unprognostic (1.59e-1)"	"unprognostic (7.88e-2)"	"unprognostic (7.62e-2)"	"prognostic favorable (2.46e-4)"
ZFHX3	"ATBF1, C16orf47, FLJ26184, ZNF927"	ENSG00000140836	"Zinc finger homeobox 3"	Q15911	16	72782885-73891871	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Myogenesis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	47	"brain: 501.8"	"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 208.5;Microglial cells: 278.2"	"Low cancer specificity"	"Detected in all"			"Region enriched"	"Detected in all"	7	"cerebral cortex: 501.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Thyroid - Thyroid glandular cells"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA059353	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 50: L-1236 & L-428 - Unknown function"	"Cluster 72: Smooth muscle cells - ECM organization"	Nucleoplasm		"HPA059353: AB_2683987"	"prognostic unfavorable (1.55e-4)"	"unprognostic (3.57e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.03e-2)"	"unprognostic (2.81e-2)"	"unprognostic (3.12e-1)"	"unprognostic (4.24e-2)"	"unprognostic (6.36e-2)"	"unprognostic (9.94e-3)"	"unprognostic (2.85e-1)"	"unprognostic (1.06e-1)"	"unprognostic (4.16e-2)"	"prognostic favorable (1.37e-5)"	"unprognostic (6.76e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.15e-2)"