Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 269.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 32: Neurons - Synaptic function" "Plasma membrane, Cell Junctions" "CAB008375: AB_592744, HPA068407: AB_2685983" "unprognostic (2.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (2.51e-2)" "unprognostic (9.24e-3)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (6.04e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-2)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 55: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 35.7;Endothelial cells: 42.3;Fibroblasts: 146.8;Smooth muscle cells: 51.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 65: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 35: Liver cancer - Metabolism" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" AFF1 "AF-4, AF4, MLLT2, PBM1" ENSG00000172493 "AF4/FMR2 family member 1" P51825 4 86935002-87141054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: Myeloma - Humoral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Mitochondria" "HPA069947: AB_2686219" "unprognostic (1.01e-1)" "unprognostic (7.56e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.55e-2)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" "unprognostic (6.09e-2)" "unprognostic (7.13e-2)" "unprognostic (1.24e-1)" "unprognostic (8.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.33e-2)" "unprognostic (4.41e-1)" "unprognostic (2.55e-1)" "unprognostic (2.71e-2)" AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 222.7;dendritic cells: 122.9;Excitatory neurons: 484.1;Inhibitory neurons: 293.5;Oligodendrocyte precursor cells: 202.6;Prostatic glandular cells: 143.4" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cancer enhanced" "Detected in many" "lymphoma: 22.4" "Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" AFF4 "AF5Q31, MCEF" ENSG00000072364 "AF4/FMR2 family member 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023690, HPA029634" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 57: Non-specific - Translation" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA023690: AB_1844633, HPA029634: AB_2673129" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.17e-3)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.13e-2)" "unprognostic (4.94e-2)" "unprognostic (3.52e-1)" "unprognostic (1.16e-2)" "unprognostic (2.77e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.69e-1)" ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 267.4;Oligodendrocyte precursor cells: 415.4" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Neuroblastoma: 81.3" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 32: Neurons - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 230.0;Excitatory neurons: 603.2;Inhibitory neurons: 255.6;Late spermatids: 214.1;Microglial cells: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 38: Neurons - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 266.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Endothelial cells, Stomach - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Myeloma - Humoral immune response" "Cluster 14: Endometrium - Transcription regulation" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 38: Non-specific - mRNA processing" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 18: Non-specific - RNA binding" "Cluster 65: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 273.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: DU4475 - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" ATF1 TREB36 ENSG00000123268 "Activating transcription factor 1" P18846 12 50763710-50821162 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016222, HPA055069, HPA055406" Supported Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 45: Non-specific - Cell proliferation" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB016222: AB_2290030, HPA055069: AB_2682688, HPA055406: AB_2682807" "unprognostic (1.71e-1)" "unprognostic (1.50e-3)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (3.65e-1)" "unprognostic (8.17e-3)" "unprognostic (5.94e-2)" "unprognostic (4.31e-3)" "unprognostic (5.52e-2)" "unprognostic (1.73e-1)" "unprognostic (2.74e-2)" "unprognostic (2.46e-1)" "unprognostic (2.27e-1)" "unprognostic (8.75e-2)" ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 181.6;Extravillous trophoblasts: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 45: Non-specific - Cell proliferation" "Cluster 28: Cytotrophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 165.0;Glandular and luminal cells: 196.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001944, HPA017925" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 14: Endometrium - Transcription regulation" "CAB001944: , HPA017925: AB_1845312" "unprognostic (3.78e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (7.06e-2)" "unprognostic (2.36e-1)" "unprognostic (9.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.92e-3)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (1.07e-1)" BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 213.6;Basal squamous epithelial cells: 157.0;dendritic cells: 519.7;Excitatory neurons: 178.1;Inhibitory neurons: 149.2;Langerhans cells: 175.7;Squamous epithelial cells: 155.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cancer enhanced" "Detected in many" "Leukemia: 31.5;lymphoma: 33.2" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: RS4;11 - Unknown function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Intellectual disability, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 84.8;Basal squamous epithelial cells: 90.5;Inhibitory neurons: 103.1;NK-cells: 137.8;Suprabasal keratinocytes: 77.0;T-cells: 295.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "Bone cancer: 18.1;Leukemia: 6.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - T-cells" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 263.2;Schwann cells: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cancer enhanced" "Detected in many" "lymphoma: 41.9;Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB000003, CAB080071, CAB080083" Enhanced Enhanced Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 44: Myeloma - Humoral immune response" "Cluster 1: T-cells - Immune response" Mitochondria "CAB000003: AB_2064429, CAB080071: , CAB080083: " "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 485.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 146.7;Skeletal myocytes: 212.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 269.1;non-classical monocyte: 76.4" "Group enriched" "Detected in all" 7 "granulocytes: 269.1;monocytes: 76.4" "Cancer enriched" "Detected in all" 4 "lymphoma: 131.8" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "Golgi apparatus" "CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199" "unprognostic (5.36e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.34e-3)" "unprognostic (2.62e-2)" "unprognostic (3.33e-3)" "unprognostic (8.75e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.27e-9)" "unprognostic (5.22e-2)" "unprognostic (7.82e-2)" "unprognostic (5.67e-2)" "unprognostic (2.58e-2)" BCL7A BCL7 ENSG00000110987 "BAF chromatin remodeling complex subunit BCL7A" Q4VC05 12 122019422-122062044 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.0;naive B-cell: 2.1;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 14 "B-cells: 2.1;dendritic cells: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019762 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Vesicles" "HPA019762: AB_10962489" "unprognostic (3.27e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (5.18e-1)" "unprognostic (5.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.13e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.86e-2)" "unprognostic (8.56e-2)" "unprognostic (6.16e-3)" "unprognostic (1.51e-2)" BCL9 ENSG00000116128 "BCL9 transcription coactivator" O00512 1 147541501-147626216 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020274 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: Non-specific - RNA binding" "Cluster 14: Endometrium - Transcription regulation" "Nucleoplasm, Nuclear bodies" "HPA020274: AB_2670400" "unprognostic (2.31e-1)" "unprognostic (1.52e-2)" "unprognostic (5.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.29e-1)" "unprognostic (4.78e-3)" "unprognostic (3.92e-2)" "unprognostic (1.64e-3)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 2: DU4475 - Unknown function" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm "HPA056308: AB_2683095, HPA073591: AB_2732227" "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.0;lymphoid tissue: 141.5" "Cell type enhanced" "Detected in many" "granulocytes: 737.3;Langerhans cells: 1603.7;monocytes: 693.9;Proximal enterocytes: 883.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 209.0;naive B-cell: 159.9" "Group enriched" "Detected in all" 13 "B-cells: 209.0;T-cells: 83.6" "Cancer enhanced" "Detected in many" "lymphoma: 122.5" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 248.6;Inhibitory neurons: 236.7;Oligodendrocyte precursor cells: 197.4;Oligodendrocytes: 191.2;Syncytiotrophoblasts: 190.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 1: T-cells - Immune response" Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" BRD3 "KIAA0043, ORFX, RING3L" ENSG00000169925 "Bromodomain containing 3" Q15059 9 134030305-134068535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 133.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051830, HPA076873" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 55: Non-specific - Unknown function" "Cluster 9: Neurons - Nervous system development" Nucleoplasm "HPA051830: AB_2681627, HPA076873: " "unprognostic (3.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.98e-2)" "unprognostic (3.48e-2)" "unprognostic (1.11e-2)" "unprognostic (6.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "prognostic favorable (2.71e-7)" "unprognostic (1.00e-1)" "unprognostic (4.71e-2)" "unprognostic (2.57e-2)" "unprognostic (1.42e-1)" BRD4 "CAP, HUNK1, HUNKI, MCAP" ENSG00000141867 "Bromodomain containing 4" O60885 19 15235519-15332545 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015055, HPA061646, CAB068177, CAB068178" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 53: Non-specific - mRNA processing" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "CAB068177: AB_2665685, CAB068178: AB_2665686, HPA015055: AB_1845435, HPA061646: AB_2684575" "unprognostic (2.83e-3)" "unprognostic (2.39e-2)" "unprognostic (6.37e-3)" "unprognostic (3.38e-2)" "unprognostic (2.15e-1)" "unprognostic (9.53e-3)" "unprognostic (3.03e-3)" "unprognostic (6.13e-2)" "unprognostic (7.63e-2)" "unprognostic (2.72e-2)" "unprognostic (3.98e-2)" "unprognostic (5.26e-2)" "unprognostic (1.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.73e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 2983.7;Langerhans cells: 3278.3;NK-cells: 2408.0;T-cells: 2859.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Fibroblast_1, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 795.2;Proximal tubular cells: 676.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: Non-specific - mRNA processing" "Cluster 77: Cardiomyocytes - Muscle contraction" Cytosol "HPA036342: AB_2675072, HPA036343: AB_10671839" "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (5.80e-2)" "unprognostic (4.14e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.10e-4)" "unprognostic (3.90e-3)" "unprognostic (8.84e-2)" "unprognostic (1.35e-3)" "unprognostic (2.17e-2)" "unprognostic (9.19e-3)" "unprognostic (1.42e-1)" "unprognostic (9.03e-3)" CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.6;Intestinal goblet cells: 152.6;Prostatic glandular cells: 103.6;Syncytiotrophoblasts: 104.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 26: Intestinal epithelial cells - Absorption" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 158.3;Respiratory ciliated cells: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 56: Ciliated cells - Cilium assembly" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" CBFA2T3 "ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4" ENSG00000129993 "CBFA2/RUNX1 partner transcriptional co-repressor 3" O75081 16 88874858-88977207 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;lymphoid tissue: 29.5" "Cell type enhanced" "Detected in many" "Adipocytes: 23.3;B-cells: 31.8;dendritic cells: 61.4;Langerhans cells: 23.4;monocytes: 29.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 35.8" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 51.2;lymphoma: 32.6" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059931, HPA062423, HPA065890" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Nucleoplasm "HPA059931: AB_2684168, HPA062423: AB_2684758, HPA065890: AB_2685575" "unprognostic (2.47e-1)" "unprognostic (2.03e-2)" "unprognostic (9.24e-3)" "unprognostic (2.62e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.13e-3)" "unprognostic (1.69e-2)" "unprognostic (1.25e-1)" "unprognostic (2.10e-1)" "unprognostic (7.30e-3)" "unprognostic (2.38e-1)" "unprognostic (7.04e-5)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (4.62e-2)" "unprognostic (9.35e-3)" CBFB PEBP2B ENSG00000067955 "Core-binding factor subunit beta" Q13951 16 67028984-67101058 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038852 Uncertain Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 36: Non-specific - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA038852: AB_10795358" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (4.66e-2)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.83e-4)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-3)" "unprognostic (1.88e-2)" "prognostic unfavorable (2.89e-8)" "unprognostic (1.03e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol NA NA 67000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Chromatin organization" Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Schwann cells: 194.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 57: Non-specific - Translation" "Cluster 16: Non-specific - RNA binding" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 906.8;Basal respiratory cells: 488.8;Ductal cells: 427.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 398.9;Granulosa cells: 412.4;Langerhans cells: 319.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 83.5;testis cancer: 89.6" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 53: Connective tissue cells - ECM organization" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transcription, Transcription regulation" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 383.7;T-cells: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 396.7" "Breast - Breast glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 31.5;granulocytes: 32.3;Langerhans cells: 63.4;Syncytiotrophoblasts: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" CD74 DHLAG ENSG00000019582 "CD74 molecule" P04233 5 150400041-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5258.9" "Cell type enhanced" "Detected in many" "B-cells: 11877.0;dendritic cells: 8770.5;Hofbauer cells: 5475.3;Langerhans cells: 27045.0;Macrophages: 6667.5;monocytes: 5775.7;Proximal enterocytes: 5559.6;Schwann cells: 10304.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11041.2;intermediate monocyte: 15961.1;memory B-cell: 26889.3;myeloid DC: 23750.6;naive B-cell: 27930.3;non-classical monocyte: 8003.3;plasmacytoid DC: 16940.0" "Group enriched" "Detected in all" 6 "B-cells: 27930.3;dendritic cells: 23750.6;monocytes: 15961.1" "Group enriched" "Detected in all" 7 "Leukemia: 912.4;lymphoma: 2863.9;Myeloma: 1700.9;skin cancer: 805.3" "Adipose visceral - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Endometrial stromal cells: 115.4;Excitatory neurons: 120.0;Microglial cells: 141.4;Oligodendrocyte precursor cells: 151.6;Oligodendrocytes: 100.4;Theca cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 104.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_1, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.1" "Cell type enhanced" "Detected in many" "Early spermatids: 168.6;Erythroid cells: 214.0;Late spermatids: 256.9;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 41.0" "Group enriched" "Detected in some" 7 "Distal enterocytes: 290.4;Enteroendocrine cells: 155.8;Intestinal goblet cells: 200.2;Paneth cells: 219.6;Proximal enterocytes: 246.7;Undifferentiated cells: 184.0" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 63.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 15.7;colorectal cancer: 56.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA049580" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "CAB002221: AB_563649, HPA045669: AB_2679413, HPA049580: AB_2680823" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.92e-1)" "unprognostic (8.11e-3)" "unprognostic (4.19e-6)" "unprognostic (1.73e-4)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (5.51e-2)" "unprognostic (6.07e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999317-167094789 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 222.3;Late spermatids: 286.2;Spermatocytes: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Approved Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 15: Non-specific - Protein binding" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" Centrosome "HPA071876: AB_2686467" "unprognostic (9.14e-2)" "unprognostic (2.24e-1)" "unprognostic (3.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (9.59e-2)" "unprognostic (1.00e-1)" "unprognostic (6.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Plasma cells - Humoral immune response" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 4: Non-specific - Transcription" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.3" "Cell type enhanced" "Detected in many" "B-cells: 64.4;dendritic cells: 121.4;Langerhans cells: 102.3;Macrophages: 50.3;Microglial cells: 41.0;monocytes: 79.3;Schwann cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 29.1;eosinophil: 17.5;intermediate monocyte: 23.5;memory B-cell: 47.3;myeloid DC: 46.2;naive B-cell: 63.3;non-classical monocyte: 29.0;plasmacytoid DC: 48.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 52.2" "Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422669 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.1" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Supported "Microtubule ends,Cytosol" NA NA 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 45: Non-specific - Cell proliferation" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Microtubule ends, Cytosol" "CAB004399: AB_671001, HPA026678: AB_1846954" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (6.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (2.51e-1)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (8.97e-2)" "unprognostic (3.26e-2)" "unprognostic (5.50e-2)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (2.52e-3)" CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Supported "Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 65: Breast cancer - Unknown function" "Cluster 12: Non-specific - Chromatin organization" "Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Early spermatids: 13.3;Late spermatids: 19.7;Oligodendrocyte precursor cells: 12.0;Oligodendrocytes: 11.7;Skeletal myocytes: 15.8;Spermatocytes: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA063097: AB_2684939" "unprognostic (1.74e-1)" "unprognostic (3.11e-2)" "unprognostic (4.84e-1)" "unprognostic (3.35e-2)" "unprognostic (6.28e-2)" "unprognostic (7.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (6.39e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.72e-3)" "unprognostic (4.62e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 172.4;Spermatocytes: 383.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Supported "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 55: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" Centrosome "Centriolar satellite, Cytosol" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1863.1;Fibroblasts: 1830.1;Leydig cells: 557.7;Pancreatic endocrine cells: 1576.7;Smooth muscle cells: 657.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1245.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 53: Connective tissue cells - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.6;Early spermatids: 9.9;Enteroendocrine cells: 27.9;Horizontal cells: 25.0;Late spermatids: 11.7;Muller glia cells: 21.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "liver cancer: 78.0" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 6: BEWO - Unknown function" "Cluster 55: Endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 49: Early spermatids - Spermatogenesis" Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 91.2;Glandular and luminal cells: 108.8;Intestinal goblet cells: 272.3" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Alveolar cells type 2, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151, HPA062116" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 4: Stomach - Digestion" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm Cytosol "CAB026151: , HPA024069: AB_1854750, HPA062116: " "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 225.4;Plasma cells: 187.5;Syncytiotrophoblasts: 166.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 8: Non-specific - Transcription" "Cluster 12: Non-specific - Chromatin organization" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: AB_2682948" "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favorable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Cell type enhanced" "Detected in some" "dendritic cells: 3.7;granulocytes: 17.2;Langerhans cells: 9.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Cancer enhanced" "Detected in some" "Leukemia: 7.6;Myeloma: 5.6" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Mast cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA075272 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 23: Langerhans cells - Immune response" "Plasma membrane" "HPA075272: " "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 38.0;Excitatory neurons: 36.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 70: Basal prostatic cells - Lipid metabolism" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 151.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 45: Non-specific - Cell proliferation" "Cluster 72: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: AB_2685092" "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 469.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 75: Myeloid cells - Innate immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" DDIT3 "CHOP, CHOP10, GADD153" ENSG00000175197 "DNA damage inducible transcript 3" P35638 12 57516588-57521737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Growth arrest, Stress response, Transcription, Transcription regulation, Unfolded protein response, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 349.0;Cardiomyocytes: 484.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 170.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058416, HPA068416" Uncertain Supported Nucleoplasm No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 11: Non-specific - Transcription" Nucleoplasm "HPA058416: AB_2683712, HPA068416: AB_2685985" "unprognostic (1.12e-1)" "unprognostic (5.33e-2)" "unprognostic (2.20e-3)" "unprognostic (4.92e-2)" "unprognostic (7.86e-3)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-4)" "unprognostic (8.55e-2)" "unprognostic (1.26e-3)" "unprognostic (9.40e-3)" "unprognostic (4.92e-2)" "unprognostic (4.16e-2)" "unprognostic (3.52e-2)" "unprognostic (3.70e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (6.76e-2)" DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665069-108940927 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 124.1;Proximal tubular cells: 143.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 60: Proximal tubular cells - Absorption" Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favorable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64498254-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 310000 "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 11: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "CAB005868: AB_446484, HPA020043: AB_1847572, HPA071154: " "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" DDX6 "HLR2, RCK, Rck/p54" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747763-118791164 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 19000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 1: T-cells - Immune response" "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavorable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" DEK D6S231E ENSG00000124795 "DEK proto-oncogene" P35659 6 18223860-18264548 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015226, HPA054505, HPA057799" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 15: Non-specific - Protein binding" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm Cytosol "CAB015226: , HPA054505: AB_2682508, HPA057799: AB_2683530" "unprognostic (6.35e-2)" "unprognostic (6.11e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (3.66e-1)" "unprognostic (5.02e-3)" "prognostic unfavorable (9.65e-4)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.49e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (2.31e-1)" "unprognostic (3.78e-1)" DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1705.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1493.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 1705.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm NA Yes 23000 "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 11: Non-specific - Transcription" Nucleoplasm "CAB017450: AB_10631418, HPA063247: AB_2684971" "unprognostic (3.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (3.83e-1)" "unprognostic (1.85e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-1)" "prognostic favorable (5.96e-4)" "unprognostic (2.20e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (6.77e-2)" EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.7" "Cell type enhanced" "Detected in many" "Adipocytes: 88.9;B-cells: 83.2;Fibroblasts: 118.0;Leydig cells: 300.0;Microglial cells: 249.0;Peritubular cells: 125.0;Smooth muscle cells: 132.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cancer enhanced" "Detected in many" "Leukemia: 15.8;lymphoma: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (7.86e-2)" "unprognostic (3.08e-2)" "unprognostic (7.29e-2)" "unprognostic (4.70e-2)" "unprognostic (2.63e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (5.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (9.62e-7)" "prognostic unfavorable (7.80e-4)" "unprognostic (5.75e-2)" "unprognostic (5.81e-2)" "unprognostic (4.37e-3)" EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Translation" Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1600000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: Non-specific - Mitochondria" "Cluster 16: Non-specific - RNA binding" Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 37.9;Granulosa cells: 30.1;monocytes: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 48: Non-specific - RNA binding" "Cluster 17: Granulosa cells - Transcription regulation" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" ELK4 SAP1 ENSG00000158711 "ETS transcription factor ELK4" P28324 1 205597556-205632011 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 329.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028863 Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 18: Non-specific - RNA binding" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm "HPA028863: AB_10602492" "unprognostic (2.08e-1)" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (2.15e-1)" "prognostic favorable (4.65e-4)" "unprognostic (2.97e-1)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.27e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.94e-6)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.08e-1)" "unprognostic (5.58e-3)" ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 162.0;Late spermatids: 302.6;Syncytiotrophoblasts: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 53: Non-specific - mRNA processing" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: AB_2679526" "unprognostic (9.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (8.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-2)" "unprognostic (6.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 169.2" "Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported Microtubules,Cytosol NA NA 25000 "Cluster 13: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 1: T-cells - Immune response" Microtubules Cytosol "HPA036687: AB_2675251, HPA036688: AB_10671968, HPA065337: AB_2685474" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "unprognostic (3.53e-3)" "unprognostic (1.79e-2)" "unprognostic (9.19e-2)" "unprognostic (8.61e-3)" "unprognostic (1.61e-2)" "unprognostic (2.96e-3)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519266 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 296.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: Non-specific - mRNA processing" "Cluster 12: Non-specific - Chromatin organization" "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 287.6;Inhibitory neurons: 475.5;Microglial cells: 208.0;Oligodendrocyte precursor cells: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 37: Neurons - Neuronal signaling" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 87.1;Endothelial cells: 103.9;granulocytes: 26.0;Microglial cells: 85.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Leukemia: 24.7;prostate cancer: 23.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.7;Astrocytes: 65.2;Cardiomyocytes: 115.8;Enteroendocrine cells: 95.1;Excitatory neurons: 65.7;Oligodendrocyte precursor cells: 130.0;Serous glandular cells: 128.6" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 75.2" "Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 21: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.8;Cholangiocytes: 23.1;Distal tubular cells: 12.4;Enteroendocrine cells: 17.5;Extravillous trophoblasts: 22.6;Melanocytes: 13.9;Syncytiotrophoblasts: 20.0" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Cholangiocyte" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: TE 441.T - Unknown function" "Cluster 55: Endocrine cells - Hormone signaling" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" ETV5 ERM ENSG00000244405 "ETS variant transcription factor 5" P41161 3 186046314-186110318 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 92.6;Oligodendrocyte precursor cells: 162.7;Syncytiotrophoblasts: 80.8" "Cancer enhanced" "Detected in all" "melanoma: 50.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009590, HPA063065, HPA073889" Approved Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "CAB009590: AB_2101008, HPA063065: AB_2684936, HPA073889: " "unprognostic (3.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.54e-2)" "unprognostic (3.30e-1)" "unprognostic (9.00e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (7.85e-9)" "unprognostic (3.52e-3)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (4.18e-2)" "unprognostic (1.48e-1)" "unprognostic (1.57e-3)" "unprognostic (6.80e-2)" "unprognostic (1.57e-1)" "unprognostic (3.58e-2)" "unprognostic (3.84e-3)" ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 144.5;Microglial cells: 210.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: Lymphoma - Adaptive immune response" "Cluster 75: Myeloid cells - Innate immune response" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Supported Nucleoplasm,Nucleoli No No 59000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" Nucleoplasm Nucleoli "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 1642.8;Syncytiotrophoblasts: 1548.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Supported "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 1: T-cells - Immune response" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 63.9;Endothelial cells: 87.8;Fibroblasts: 54.4;Langerhans cells: 336.1;Macrophages: 128.4;Plasma cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 14.3;lymphoma: 24.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Sinusoid Endothelial cells, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.5" "Cell type enriched" "Detected in single" 4 "B-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.6" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "HPA054030: " "unprognostic (6.06e-2)" "unprognostic (3.41e-3)" "unprognostic (2.57e-1)" "unprognostic (5.08e-2)" "unprognostic (4.69e-4)" "unprognostic (2.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (3.37e-1)" "unprognostic (6.77e-2)" FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 70 "Enteroendocrine cells: 541.3" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 37.2" "Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 55: Endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 179.2;Leydig cells: 196.8;Oligodendrocyte precursor cells: 159.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 202.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 65: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 397.6;Basal keratinocytes: 99.4;Cholangiocytes: 71.2;Suprabasal keratinocytes: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 149.7" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: Myeloma - Humoral immune response" "Cluster 63: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in all" "Astrocytes: 590.9;Excitatory neurons: 272.5;Inhibitory neurons: 441.2;Microglial cells: 328.4;Oligodendrocyte precursor cells: 1040.7;Oligodendrocytes: 1048.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" FIP1L1 "DKFZp586K0717, FIP1" ENSG00000145216 "Factor interacting with PAPOLA and CPSF1" Q6UN15 4 53377641-53460862 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "mRNA processing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "HPA037475, HPA058202, HPA079225, HPA079228" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" Nucleoplasm "HPA037475: AB_10696933, HPA058202: AB_2683636, HPA079225: , HPA079228: " "unprognostic (3.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.60e-3)" "unprognostic (1.40e-1)" "unprognostic (7.18e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.87e-1)" "unprognostic (9.00e-3)" "unprognostic (1.14e-2)" "unprognostic (5.48e-2)" "unprognostic (1.42e-1)" "unprognostic (4.07e-1)" "unprognostic (1.10e-1)" "unprognostic (8.66e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 62.6;Endothelial cells: 81.0;Kupffer cells: 94.4;Macrophages: 57.9;Microglial cells: 225.3;monocytes: 83.6;NK-cells: 75.3;T-cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.1;Myeloma: 20.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 7: NK-cells - Immune response regulation" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 171.8;Endometrial stromal cells: 107.3;Granulosa cells: 103.0;Microglial cells: 114.0;Oligodendrocytes: 124.1;Skeletal myocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 17: Granulosa cells - Transcription regulation" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" FOXO3 "AF6q21, FKHRL1, FOXO2, FOXO3A" ENSG00000118689 "Forkhead box O3" O43524 6 108559835-108684774 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004074, HPA063104" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 44: Myeloma - Humoral immune response" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "CAB004074: AB_2106672, HPA063104: AB_2684941" "unprognostic (3.42e-2)" "unprognostic (3.76e-2)" "unprognostic (4.28e-2)" "unprognostic (1.96e-2)" "unprognostic (6.68e-2)" "unprognostic (4.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" "unprognostic (5.18e-2)" "unprognostic (1.98e-2)" "unprognostic (1.75e-1)" "unprognostic (2.54e-2)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "unprognostic (5.81e-2)" "unprognostic (5.68e-2)" FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 262.5;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: BEWO - Unknown function" "Cluster 28: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 39: Non-specific - Translation" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Extravillous trophoblasts: 4345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" FUS "ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS" ENSG00000089280 "FUS RNA binding protein" P35637 16 31180138-31191605 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008784, CAB033036, CAB058691" Supported Supported Nucleoplasm NA NA 480000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 53: Non-specific - mRNA processing" "Cluster 11: Non-specific - Transcription" Nucleoplasm "CAB033036: AB_2105208, CAB058691: AB_2665583, HPA008784: AB_1849181" "unprognostic (3.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.86e-2)" "unprognostic (8.68e-2)" "unprognostic (1.44e-1)" "unprognostic (8.03e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (5.22e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-3)" "unprognostic (1.12e-3)" "unprognostic (1.87e-1)" "unprognostic (5.27e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 131.6;Oligodendrocytes: 154.2;Schwann cells: 262.9" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cancer enriched" "Detected in many" 5 "skin cancer: 129.1" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 33: Skin cancer - Membrane components" "Cluster 65: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 46: Non-specific - Unknown function" "Cluster 40: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" GOPC "CAL, dJ94G16.2, FIG, GOPC1, PIST" ENSG00000047932 "Golgi associated PDZ and coiled-coil motif containing" Q9HD26 6 117560269-117602542 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "HPA019477, HPA024018" Approved Enhanced "Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: Non-specific - Protein binding" "Cluster 52: Endometrial stromal cells - ECM organization" "Golgi apparatus" "HPA019477: AB_1849890, HPA024018: AB_1849891" "unprognostic (2.48e-2)" "unprognostic (1.63e-3)" "unprognostic (1.71e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (3.12e-2)" "unprognostic (9.21e-2)" "unprognostic (6.22e-2)" "unprognostic (6.77e-2)" "unprognostic (8.23e-2)" "unprognostic (9.46e-2)" "unprognostic (1.40e-2)" "unprognostic (2.67e-2)" "unprognostic (1.38e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-2)" GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 477.6;Excitatory neurons: 676.4;Inhibitory neurons: 846.3;Oligodendrocyte precursor cells: 551.6;Oligodendrocytes: 564.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 46: Non-specific - Unknown function" "Cluster 37: Neurons - Neuronal signaling" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" H4C9 "H4/m, H4FM, HIST1H4I" ENSG00000276180 "H4 clustered histone 9" P62805 6 27138588-27139881 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 2.7;Erythroid cells: 2.3;Plasma cells: 5.5;Undifferentiated cells: 3.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA042201 Approved NA NA 25000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 1: Non-specific - Nucleosome assembly" "Cluster 40: Plasma cells - Humoral immune response" "HPA042201: AB_2677898" "unprognostic (2.49e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.97e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (6.28e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-1)" "unprognostic (2.02e-2)" HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 2251.5;Plasma cells: 2092.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 314.4" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 101.5;Extravillous trophoblasts: 131.5;granulocytes: 141.0" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 46: Granulocytes - Mast cell degranulation" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1398.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: Non-specific - Transcription" "Cluster 6: Late spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3575.6;NK-cells: 3270.5;Proximal enterocytes: 5332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - T-cells" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 19: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 63.2;Bipolar cells: 102.0;Excitatory neurons: 76.3;Hepatocytes: 148.9;Horizontal cells: 116.0;Microglial cells: 72.1;Muller glia cells: 62.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.0" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: Liver cancer - Metabolism" "Cluster 13: Hepatocytes - Oxidoreductase activity" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 275.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 941.5;Ductal cells: 599.7;Extravillous trophoblasts: 705.5;Syncytiotrophoblasts: 701.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.9;Early spermatids: 19.2;Glandular and luminal cells: 12.6;Granulosa cells: 29.8;Smooth muscle cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 18: Non-specific - Mixed function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Supported Nucleoplasm "Intracellular and membrane" NA NA 11000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 63: Non-specific - Unknown function" "Cluster 11: Non-specific - Transcription" Nucleoplasm "CAB012403: , HPA001666: AB_1850836, HPA005812: AB_2667441, HPA065537: AB_2685507" "unprognostic (1.19e-1)" "unprognostic (4.45e-1)" "unprognostic (2.33e-1)" "unprognostic (6.39e-2)" "unprognostic (5.64e-2)" "unprognostic (8.04e-3)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.25e-2)" "unprognostic (9.12e-3)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.12e-4)" "prognostic unfavorable (8.01e-5)" "unprognostic (6.74e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Chromatin organization" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 21 "Endometrial stromal cells: 124.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 26: NCI-H716 - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enhanced" "Detected in some" "Club cells: 13.5;Distal enterocytes: 27.5;Enteroendocrine cells: 10.4;Fibroblasts: 7.0;Intestinal goblet cells: 9.7;Paneth cells: 10.3;Prostatic glandular cells: 37.1;Undifferentiated cells: 9.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 12.4" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 62.2;Endometrial stromal cells: 28.3;Enteroendocrine cells: 26.3;Intestinal goblet cells: 27.3;Proximal tubular cells: 72.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 54.8" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: DU4475 - Unknown function" "Cluster 60: Proximal tubular cells - Absorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.2;Langerhans cells: 1.4;Proximal enterocytes: 3.5;Spermatocytes: 3.4;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 17.2" "Breast - Breast glandular cells (progenitors), Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 65: Breast cancer - Unknown function" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Breast myoepithelial cells: 4.3;Melanocytes: 1.7;Spermatogonia: 1.6;Suprabasal keratinocytes: 2.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 21.7;Distal enterocytes: 15.0;Endometrial stromal cells: 27.8;Enteroendocrine cells: 14.6;Intestinal goblet cells: 8.5;Paneth cells: 6.5;Undifferentiated cells: 8.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Kidney - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: Bone cancer - Transcription" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Club cells: 3.3;Distal enterocytes: 10.8;Enteroendocrine cells: 13.2;Intestinal goblet cells: 9.5;Paneth cells: 6.0;Undifferentiated cells: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Bone cancer: 38.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: Bone cancer - Transcription" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2527.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002058, HPA047290" Approved Enhanced Cytosol NA NA 71000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 46: Non-specific - Unknown function" "Cluster 11: Non-specific - Transcription" Cytosol "CAB002058: , HPA047290: " "prognostic unfavorable (5.59e-4)" "unprognostic (3.77e-2)" "unprognostic (1.78e-2)" "unprognostic (9.25e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (7.79e-3)" "unprognostic (5.71e-2)" "unprognostic (7.81e-3)" "unprognostic (3.68e-2)" "unprognostic (1.65e-2)" "prognostic favorable (1.18e-5)" "unprognostic (1.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 15: Non-specific - Protein binding" "Cluster 11: Non-specific - Transcription" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 161.5;dendritic cells: 378.3;Langerhans cells: 115.3;monocytes: 150.7;NK-cells: 323.4;T-cells: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 131 "Leukemia: 92.0;lymphoma: 124.9;Myeloma: 43.3" "Adipose visceral - T-cells, Colon - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-cells: 8.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" NA NA 20300 "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 12.3;Hofbauer cells: 7.7;Langerhans cells: 19.5;monocytes: 11.5;NK-cells: 29.6;T-cells: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 46.5;Myeloma: 25.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391752-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.2;cervix: 19.0;lymphoid tissue: 26.1" "Cell type enriched" "Detected in some" 5 "dendritic cells: 1192.0" "Cancer enriched" "Detected in many" 9 "melanoma: 27.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 10.4;myeloid DC: 10.6;naive B-cell: 10.8;plasmacytoid DC: 12.1;T-reg: 5.8" "Group enriched" "Detected in many" 5 "B-cells: 10.8;dendritic cells: 12.1;T-cells: 5.8" "Group enriched" "Detected in some" 11 "lymphoma: 130.9;Myeloma: 281.6" "Stomach - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Nucleoplasm Cytosol "CAB013508: , HPA002038: AB_1079148, HPA002698: AB_1851893" "prognostic favorable (6.44e-4)" "unprognostic (1.88e-3)" "unprognostic (1.00e-3)" "unprognostic (1.72e-4)" "unprognostic (2.74e-1)" "prognostic favorable (1.64e-6)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.74e-4)" "unprognostic (8.51e-2)" "unprognostic (1.12e-1)" "unprognostic (9.18e-7)" "unprognostic (2.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.65e-2)" IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108719946-108736563 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.7;choroid plexus: 8.0;pituitary gland: 5.3" "Cell type enriched" "Detected in some" 4 "Melanocytes: 13.9" "Cancer enhanced" "Detected in some" "breast cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "Rhabdoid: 50.2" "Lung - Respiratory ciliated cells" "Group enriched" "Detected in many" 5 "basal ganglia: 11.7;hypothalamus: 45.0" "Group enriched" "Detected in many" 5 "basal ganglia: 14.5;hypothalamus: 36.7" HPA017372 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "HPA017372: AB_2669600" "unprognostic (3.74e-3)" "unprognostic (3.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (9.28e-4)" "unprognostic (8.71e-2)" ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Cell type enhanced" "Detected in some" "granulocytes: 29.4;NK-cells: 75.1;Serous glandular cells: 22.9;T-cells: 127.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 44 "Leukemia: 7.3;lymphoma: 5.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 92.1;Inhibitory neurons: 119.4;Microglial cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 64: Non-specific - Transcription" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74824927-75032624 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 1: T-cells - Immune response" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favorable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 14: Bone cancer - Transcription" "Cluster 65: Fibroblasts - ECM organization" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 693.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 15: Smooth muscle cells - Muscle contraction" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 360 "Prostatic glandular cells: 6533.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 122 "prostate cancer: 220.0" "Prostate - Prostate glandular cells" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 73: Prostatic glandular cells - Transcription" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 64: Non-specific - Transcription" Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Group enriched" "Detected in many" 4 "Spermatocytes: 319.1;Spermatogonia: 108.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 45: Non-specific - Cell proliferation" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1591.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 77: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 597.8;Proximal enterocytes: 281.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 65: Breast cancer - Unknown function" "Cluster 6: Late spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "NK-cells: 191.1;T-cells: 253.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in many" 5 "Leukemia: 91.2;lymphoma: 54.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 7: NK-cells - Immune response regulation" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 342.0;Astrocytes: 365.0;Endothelial cells: 339.3;Oligodendrocytes: 260.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: Liver cancer - Metabolism" "Cluster 66: Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 1695.3;Langerhans cells: 1699.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 75: Myeloid cells - Innate immune response" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;skeletal muscle: 29.3;tongue: 12.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 28.0;Early spermatids: 63.3;Horizontal cells: 14.7;Pancreatic endocrine cells: 53.2" "Cancer enriched" "Detected in many" 6 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.2;Neuroblastoma: 20.1" "Pancreas - Alpha cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 47: Retina - Visual perception" "Cluster 49: Early spermatids - Spermatogenesis" "unprognostic (3.74e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-6)" "unprognostic (9.34e-2)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.06e-3)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (9.05e-2)" "unprognostic (4.36e-12)" "unprognostic (1.76e-2)" "unprognostic (8.88e-2)" "unprognostic (2.58e-2)" "unprognostic (3.13e-2)" LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 108.4;Endothelial cells: 156.7;Erythroid cells: 86.4;monocytes: 120.3" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cancer enriched" "Detected in many" 4 "Leukemia: 47.0" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1783.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Endothelial cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 15: Smooth muscle cells - Muscle contraction" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 41: Non-specific - Cilium assembly" "Cluster 52: Endometrial stromal cells - ECM organization" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 36.7" "Group enriched" "Detected in many" 4 "Early spermatids: 213.3;Late spermatids: 830.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Group enriched" "Detected in many" 11 "Leukemia: 112.9;lymphoma: 33.5" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA072177 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 71: Erythroid cells - Oxygen transport" Nucleoplasm "HPA072177: " "unprognostic (8.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-2)" "unprognostic (3.29e-3)" "unprognostic (2.76e-1)" "unprognostic (3.64e-3)" "unprognostic (2.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (1.78e-3)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.18e-1)" "unprognostic (6.54e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-1)" MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 258.3;Inhibitory neurons: 370.1;Proximal enterocytes: 284.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Cancer enriched" "Detected in many" 6 "Myeloma: 55.5" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: Myeloma - Humoral immune response" "Cluster 12: Non-specific - Chromatin organization" "Nucleoplasm, Nuclear bodies" Vesicles "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 404.8;Kupffer cells: 407.4;Macrophages: 500.9;monocytes: 673.1;Squamous epithelial cells: 374.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cancer enhanced" "Detected in many" "Bone cancer: 31.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 14: Bone cancer - Transcription" "Cluster 69: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 219.2;Langerhans cells: 134.4;monocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 68: Kidney - Mixed function" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 669.0;Microglial cells: 564.6;Oligodendrocyte precursor cells: 1245.7;Oligodendrocytes: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: AB_10671101" "unprognostic (8.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.08e-2)" "unprognostic (9.07e-2)" "unprognostic (3.57e-3)" "unprognostic (3.32e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (9.11e-2)" "prognostic favorable (1.90e-4)" "unprognostic (9.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Adipocytes: 117.3;Collecting duct cells: 169.3;Gastric mucus-secreting cells: 117.5;Glandular and luminal cells: 134.0;Microglial cells: 337.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 14: Endometrium - Transcription regulation" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" MLF1 ENSG00000178053 "Myeloid leukemia factor 1" P58340 3 158571163-158607252 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Differentiation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.3;testis: 393.7" "Group enriched" "Detected in many" 11 "Early spermatids: 3781.7;Late spermatids: 13605.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.7" "Lineage enriched" "Detected in single" 9 "T-cells: 8.7" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA069479, HPA079339" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 43: Non-specific - Mitochondria" "Cluster 51: Late spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA069479: AB_2686140, HPA079339: " "unprognostic (6.49e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.72e-2)" "unprognostic (2.65e-2)" "unprognostic (8.55e-2)" "unprognostic (4.11e-2)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.21e-2)" "unprognostic (1.07e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (5.54e-4)" "unprognostic (9.34e-3)" "unprognostic (2.47e-3)" "unprognostic (3.36e-2)" MLLT1 "ENL, LTG19, YEATS1" ENSG00000130382 "MLLT1 super elongation complex subunit" Q03111 19 6210381-6279975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Cytotrophoblasts: 570.8;Syncytiotrophoblasts: 1092.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031166 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 53: Non-specific - mRNA processing" "Cluster 28: Cytotrophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA031166: AB_10601874" "unprognostic (3.21e-1)" "unprognostic (2.75e-3)" "unprognostic (4.84e-2)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "prognostic favorable (6.03e-5)" "unprognostic (1.30e-3)" "unprognostic (1.44e-2)" "unprognostic (1.56e-1)" "unprognostic (1.98e-1)" "unprognostic (3.93e-3)" "unprognostic (4.76e-2)" "unprognostic (3.65e-3)" "unprognostic (1.14e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.99e-3)" MLLT10 AF10 ENSG00000078403 "MLLT10 histone lysine methyltransferase DOT1L cofactor" P55197 10 21524646-21743630 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 198.4;Inhibitory neurons: 165.8;Spermatocytes: 221.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005736, HPA005747, HPA072790" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 67: Non-specific - Mitochondria & RNA binding" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA005736: , HPA005747: AB_1079393, HPA072790: " "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (1.31e-2)" "prognostic favorable (8.75e-4)" "unprognostic (1.03e-3)" "unprognostic (9.56e-3)" "unprognostic (9.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.69e-2)" "unprognostic (7.85e-2)" "unprognostic (6.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 231.8" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 255.4;testis cancer: 142.5" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: Neuroblastoma - Neuronal signaling" "Cluster 9: Neurons - Nervous system development" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" MLLT3 "AF-9, AF9, YEATS3" ENSG00000171843 "MLLT3 super elongation complex subunit" P42568 9 20341669-20622499 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 140.1;Excitatory neurons: 280.1;Inhibitory neurons: 281.7;Intestinal goblet cells: 132.2;Microglial cells: 111.3;Oligodendrocyte precursor cells: 243.6;Oligodendrocytes: 204.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 5.1;T-cells: 16.3" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001824 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm Cytosol "HPA001824: AB_1079394" "unprognostic (3.31e-1)" "unprognostic (2.22e-1)" "unprognostic (1.23e-3)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (3.83e-2)" "unprognostic (1.01e-3)" "unprognostic (2.12e-1)" "unprognostic (3.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.81e-2)" "unprognostic (1.40e-2)" "unprognostic (1.68e-1)" MLLT6 "AF17, FLJ23480" ENSG00000275023 "MLLT6, PHD finger containing" P55198 17 38705273-38729795 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 269.8;NK-cells: 157.0;Rod photoreceptor cells: 210.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004021 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 64: Non-specific - Transcription" Nucleoplasm "HPA004021: AB_1853995" "prognostic favorable (4.18e-4)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (1.44e-2)" "unprognostic (1.29e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.98e-2)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (7.12e-3)" "prognostic favorable (7.41e-4)" "unprognostic (1.78e-1)" "unprognostic (1.84e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.05e-1)" "unprognostic (2.46e-3)" MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Early spermatids: 15.6;Fibroblasts: 13.7;Horizontal cells: 17.3;Late spermatids: 18.1;Skeletal myocytes: 25.7;Thymic epithelial cells: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 122.1;Inhibitory neurons: 99.6;Late spermatids: 130.8;Oligodendrocytes: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.4" "Group enriched" "Detected in all" 5 "dendritic cells: 93.1;granulocytes: 189.4;monocytes: 58.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030782 Approved Supported Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Unknown function" "Cluster 36: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA030782: AB_10600930" "unprognostic (7.90e-3)" "unprognostic (4.51e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (9.37e-2)" "unprognostic (4.38e-3)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-2)" "prognostic unfavorable (1.58e-7)" "unprognostic (9.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.30e-2)" "unprognostic (3.98e-1)" MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 804.4;Cone photoreceptor cells: 339.5;Rod photoreceptor cells: 566.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 63: Astrocytes - Nervous system maintenance" Cytosol "CAB022300: , HPA068990: " "unprognostic (4.73e-2)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-2)" "unprognostic (4.89e-2)" "unprognostic (2.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.22e-8)" "prognostic favorable (2.00e-4)" "unprognostic (4.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 506.8;NK-cells: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.9;Granulosa cells: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 48: Non-specific - RNA binding" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 973.8;Alveolar cells type 2: 1409.1;Exocrine glandular cells: 988.8;Gastric mucus-secreting cells: 578.9;Ionocytes: 454.7;Respiratory ciliated cells: 564.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 158.7;pancreatic cancer: 182.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 46: Non-specific - Unknown function" "Cluster 74: Pancreatic cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 35.2;breast: 20.1;intestine: 26.5;lymphoid tissue: 66.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 39.0;dendritic cells: 30.2;Distal enterocytes: 32.1;Enteroendocrine cells: 31.0;Erythroid cells: 92.8;granulocytes: 40.2;Intestinal goblet cells: 32.5;Respiratory ciliated cells: 30.5;Undifferentiated cells: 50.7" "Group enriched" "Detected in many" 5 "breast cancer: 17.7;colorectal cancer: 16.4;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 4.6;eosinophil: 5.4;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.4" "Cancer enhanced" "Detected in many" "Leukemia: 173.5" "Adipose subcutaneous - Mast cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 26: Intestinal epithelial cells - Absorption" Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favorable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favorable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 608.5;Basal squamous epithelial cells: 1003.2;Squamous epithelial cells: 684.3;Suprabasal keratinocytes: 640.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: Myeloma - Humoral immune response" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 4 "Peritubular cells: 1667.8;Smooth muscle cells: 1154.9" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.9;Rhabdoid: 1.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 598.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 15: Smooth muscle cells - Muscle contraction" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 47.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 347.8;Inhibitory neurons: 235.5;Melanocytes: 146.3;Oligodendrocyte precursor cells: 316.7;Oligodendrocytes: 381.5" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 64.7" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" NAB2 MADER ENSG00000166886 "NGFI-A binding protein 2" Q15742 12 57089043-57095476 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 48.4;Syncytiotrophoblasts: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004510, HPA027464" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 75: Myeloid cells - Innate immune response" "Nucleoplasm, Cytosol" "CAB004510: AB_627982, HPA027464: AB_10601138" "prognostic favorable (7.41e-4)" "unprognostic (4.04e-2)" "unprognostic (2.20e-3)" "unprognostic (2.43e-2)" "unprognostic (4.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-3)" "unprognostic (1.80e-1)" "unprognostic (5.85e-2)" "unprognostic (1.19e-1)" "unprognostic (2.13e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.38e-6)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (5.67e-3)" "unprognostic (6.19e-3)" NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 453.0;Excitatory neurons: 308.5;Inhibitory neurons: 411.9;Microglial cells: 332.9;Oligodendrocyte precursor cells: 440.0;Oligodendrocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 156.6;Excitatory neurons: 156.5;Inhibitory neurons: 307.7;Microglial cells: 227.1;Oligodendrocyte precursor cells: 239.2;Oligodendrocytes: 175.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 4: Platelets - Platelet activation" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 534.1;Proximal enterocytes: 394.4;Suprabasal keratinocytes: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 68: Kidney - Mixed function" "Cluster 22: Squamous epithelial cells - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" NFATC2 "NF-ATP, NFAT1, NFATp" ENSG00000101096 "Nuclear factor of activated T cells 2" Q13469 20 51386957-51562831 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 26.0" "Cell type enhanced" "Detected in many" "Melanocytes: 108.0;Microglial cells: 94.0;NK-cells: 81.1;T-cells: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008789, CAB018567, HPA024369" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 33: Skin cancer - Membrane components" "Cluster 2: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "CAB018567: AB_628012, HPA008789: AB_1079474, HPA024369: AB_1854413" "unprognostic (2.69e-3)" "unprognostic (2.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.26e-2)" "unprognostic (3.94e-2)" "unprognostic (4.05e-2)" "unprognostic (9.26e-2)" "unprognostic (3.74e-3)" "unprognostic (2.17e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (9.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.05e-2)" "unprognostic (6.59e-2)" NFIB "NFI-RED, NFIB2, NFIB3" ENSG00000147862 "Nuclear factor I B" O00712 9 14081843-14398983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 525.7;Mucus glandular cells: 509.2;Oligodendrocyte precursor cells: 541.5;Salivary duct cells: 487.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003956 Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 32: Neurons - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "HPA003956: AB_1854424" "unprognostic (1.93e-1)" "unprognostic (3.18e-2)" "unprognostic (4.00e-1)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (4.72e-3)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (3.68e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.53e-4)" "unprognostic (4.69e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 145.1;monocytes: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 75: Myeloid cells - Innate immune response" Cytosol Nucleoplasm "CAB022098: , HPA008422: AB_1854434, HPA023900: AB_1854435" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (1.53e-2)" "unprognostic (8.08e-3)" "unprognostic (2.15e-1)" "unprognostic (2.38e-3)" "unprognostic (3.98e-2)" "prognostic favorable (8.45e-5)" "unprognostic (4.04e-1)" "unprognostic (8.34e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.69e-12)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (4.90e-2)" "unprognostic (1.56e-1)" NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "dendritic cells: 137.6;Excitatory neurons: 237.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 38: Neurons - Neuronal signaling" "Nucleoli, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 48: Non-specific - RNA binding" "Cluster 39: Non-specific - Translation" Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 54.6;Astrocytes: 65.2;Endothelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 66: Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 57: Non-specific - Translation" "Cluster 39: Non-specific - Translation" "Nucleoli rim" Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (7.48e-4)" "prognostic unfavorable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 312.4;dendritic cells: 547.4;granulocytes: 376.7;Langerhans cells: 501.7;Schwann cells: 286.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cervical cancer: 4.0;skin cancer: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 75: Myeloid cells - Innate immune response" "HPA043360: AB_10961186" "prognostic favorable (5.97e-4)" "unprognostic (6.92e-3)" "unprognostic (5.34e-2)" "unprognostic (2.78e-3)" "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (2.89e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-3)" "unprognostic (1.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-3)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 14 "Excitatory neurons: 1447.3;Inhibitory neurons: 398.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 61: Liver - Metabolism" "Cluster 38: Neurons - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 57: Non-specific - Translation" "Cluster 64: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm No No "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Cell proliferation" Nucleoplasm "CAB068246: AB_2665690, CAB068247: AB_2665689, HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavorable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018893 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: T-cells - Immune response" Mitochondria Nucleoplasm "HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 25.4;granulocytes: 30.0;Horizontal cells: 18.6" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Group enriched" "Detected in some" 6 "Leukemia: 8.5;Neuroblastoma: 17.7" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 62: Granulocytes - Innate immune response" "Cluster 46: Granulocytes - Mast cell degranulation" "Vesicles, Cytosol" "CAB004606: AB_628397, CAB080140: , HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 231.9;Early spermatids: 115.0;Excitatory neurons: 355.3;Inhibitory neurons: 271.7;Late spermatids: 154.8;Microglial cells: 172.4;Oligodendrocyte precursor cells: 478.5" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.8;Neuroblastoma: 8.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 38: Neurons - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125586-131234663 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 124.2" "Cell type enhanced" "Detected in many" "Early spermatids: 245.3;Granulosa cells: 157.4;Hofbauer cells: 175.4;Kupffer cells: 256.7;Late spermatids: 401.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 425.3;neutrophil: 1259.6" "Group enriched" "Detected in all" 5 "granulocytes: 1259.6;monocytes: 425.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 33: Macrophages - Degranulation" "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" NUP98 "NUP96, Nup98-96, Nup98-Nup96" ENSG00000110713 "Nucleoporin 98 and 96 precursor" P52948 11 3671083-3797792 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 165.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 1: T-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.41e-2)" "unprognostic (2.13e-1)" "unprognostic (7.71e-3)" "unprognostic (3.40e-1)" "unprognostic (4.08e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (7.76e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (5.09e-1)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" NUTM1 "C15orf55, DKFZp434O192, FAM22H, NUT" ENSG00000184507 "NUT midline carcinoma family member 1" Q86Y26 15 34343315-34357737 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 19.8" "Cell type enriched" "Detected in some" 11 "Early spermatids: 108.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Gallbladder cancer: 1.8" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA040421 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 41: Non-specific - Cilium assembly" "Cluster 57: Early spermatids - Flagellum & Golgi organization" "HPA040421: AB_10793965" "unprognostic (4.14e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-1)" "unprognostic (7.38e-2)" "unprognostic (1.99e-1)" "unprognostic (8.37e-2)" "unprognostic (8.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-2)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (4.27e-2)" "unprognostic (4.79e-2)" NUTM2B "bA119F19.1, FAM22B" ENSG00000188199 "NUT family member 2B" A6NNL0 10 79703227-79714681 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 42: Spermatocytes & Spermatids - Spermatogenesis" "Nuclear bodies" "HPA064635: " "unprognostic (9.51e-2)" "unprognostic (6.09e-2)" "unprognostic (1.21e-2)" "unprognostic (1.10e-1)" "unprognostic (3.63e-1)" "unprognostic (6.60e-2)" "unprognostic (2.47e-2)" "unprognostic (7.66e-2)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (7.79e-3)" "unprognostic (1.15e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (5.72e-2)" "unprognostic (5.37e-2)" "unprognostic (2.32e-2)" NUTM2D FAM22D ENSG00000214562 "NUT family member 2D" Q5VT03 10 87357720-87370695 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.5;Cardiomyocytes: 1.3;Gastric mucus-secreting cells: 1.2;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 9: Neurons - Nervous system development" "Nuclear bodies" "HPA064635: " "unprognostic (2.13e-1)" "unprognostic (7.95e-2)" "unprognostic (3.94e-2)" "unprognostic (2.16e-1)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (7.35e-4)" "unprognostic (1.87e-1)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.46e-1)" "unprognostic (3.57e-1)" "unprognostic (7.76e-3)" "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (2.32e-1)" OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 87.2" "Group enriched" "Detected in some" 22 "Oligodendrocyte precursor cells: 118.9;Oligodendrocytes: 37.7" "Cancer enriched" "Detected in some" 52 "glioma: 46.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;Sarcoma: 3.4;skin cancer: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 62: Granulocytes - Innate immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: AB_1854795" "unprognostic (5.14e-1)" "unprognostic (4.56e-1)" "unprognostic (1.44e-2)" "unprognostic (8.27e-2)" "unprognostic (3.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (5.78e-5)" "unprognostic (2.76e-1)" P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "B-cells: 42.1;Kupffer cells: 15.6;NK-cells: 72.2;Plasma cells: 37.5;T-cells: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 32 "Leukemia: 62.4;lymphoma: 76.5;Myeloma: 48.9" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - T-cells" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 7: NK-cells - Immune response regulation" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 58: Non-specific - Basic cellular processes" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 39: Non-specific - Unknown function" "Cluster 70: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 16.8;Late spermatids: 36.9;Melanocytes: 59.2;Skeletal myocytes: 11.9" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 10.9;skin cancer: 21.0" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 6: Late spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 9 "B-cells: 112.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 11 "Leukemia: 32.8;lymphoma: 76.6" "Lung - B-cells, Skin - Outer root sheath cells" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm "CAB026269: , CAB026869: , HPA056394: AB_2683116" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" PAX7 Hup1 ENSG00000009709 "Paired box 7" P23759 1 18630846-18748866 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 4.2;skeletal muscle: 5.7;tongue: 4.4" "Cell type enriched" "Detected in some" 8 "Skeletal myocytes: 11.9" "Group enriched" "Detected in some" 6 "breast cancer: 0.5;cervical cancer: 1.5;lung cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Bone cancer: 55.9" "Region enriched" "Detected in single" 17 "midbrain: 4.6" "Region enhanced" "Detected in some" "thalamus: 4.3" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 14: Bone cancer - Transcription" "Cluster 11: Non-specific - Transcription" "unprognostic (8.41e-4)" "unprognostic (2.07e-1)" "unprognostic (5.35e-2)" "unprognostic (3.96e-2)" "unprognostic (4.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" PAX8 ENSG00000125618 "Paired box 8" Q06710 2 113215997-113278921 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 267.9;thyroid gland: 565.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 61.2;Collecting duct cells: 224.5;Endometrial ciliated cells: 111.0;Glandular and luminal cells: 238.3;Proximal tubular cells: 118.2" "Group enriched" "Detected in many" 12 "endometrial cancer: 60.6;ovarian cancer: 63.5;renal cancer: 33.2;thyroid cancer: 122.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Kidney cancer: 84.3;ovarian cancer: 113.7;Sarcoma: 52.1;thyroid cancer: 58.5;Uterine cancer: 119.5" "Region enriched" "Detected in some" 4 "pons and medulla: 5.5" "HPA030062, CAB055097, CAB061888, HPA064554" Enhanced Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm "CAB055097: AB_2236705, CAB061888: AB_10895719, HPA030062: AB_10603982, HPA064554: AB_2685283" "unprognostic (2.63e-3)" "unprognostic (3.80e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (7.24e-2)" "unprognostic (5.16e-5)" "unprognostic (1.56e-2)" "unprognostic (3.29e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (4.13e-2)" "unprognostic (4.00e-2)" "unprognostic (3.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.37e-1)" "unprognostic (8.93e-3)" "unprognostic (1.02e-1)" PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.4;Excitatory neurons: 469.2;Inhibitory neurons: 395.5;Oligodendrocyte precursor cells: 313.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 65: Breast cancer - Unknown function" "Cluster 32: Neurons - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922840-18027975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 581.4;Spermatocytes: 530.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 64: Non-specific - Transcription" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB058695: AB_2665588, HPA023370: AB_1855072, HPA023374: AB_1855073" "unprognostic (1.52e-2)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (3.35e-2)" "unprognostic (9.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.74e-3)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.83e-1)" "unprognostic (1.76e-2)" "unprognostic (2.16e-1)" "unprognostic (4.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.9;Fibroblasts: 7.3;granulocytes: 12.6;Langerhans cells: 14.1;Leydig cells: 6.9;Microglial cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 23: Langerhans cells - Immune response" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 730.8;Skeletal myocytes: 722.5;Syncytiotrophoblasts: 217.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Lymphoma - Cytokine signaling" "Cluster 77: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.4;dendritic cells: 67.4;Endothelial cells: 80.2;Exocrine glandular cells: 64.5;Langerhans cells: 77.8;Macrophages: 45.1;Schwann cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 68: Kidney - Mixed function" "Cluster 75: Myeloid cells - Innate immune response" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 374.7;Fibroblasts: 250.2;Leydig cells: 430.4;Oligodendrocyte precursor cells: 478.5;Peritubular cells: 384.7" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 76.7;thyroid cancer: 37.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 52: Endometrial stromal cells - ECM organization" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 139.1;Leydig cells: 161.7;Peritubular cells: 206.1;Sertoli cells: 522.4;Smooth muscle cells: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Brain cancer: 30.9;testis cancer: 38.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 59: Fibroblasts - Metabolism" "Cluster 72: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" PER1 "PER, RIGUI" ENSG00000179094 "Period circadian regulator 1" O15534 17 8140472-8156506 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047947, HPA067064" Supported Nucleoplasm,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 49: Non-specific - Unknown function" "Cluster 1: T-cells - Immune response" Cytosol Nucleoplasm "HPA047947: AB_2680219, HPA067064: AB_2685774" "unprognostic (7.64e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.54e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.67e-2)" "unprognostic (6.21e-3)" "unprognostic (6.87e-2)" "unprognostic (4.68e-2)" "unprognostic (7.09e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.08e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-2)" PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 487.1;Oligodendrocytes: 669.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 12: Non-specific - Chromatin organization" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 219.0" "Cell type enhanced" "Detected in many" "Plasma cells: 187.4;Suprabasal keratinocytes: 212.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 321.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 321.3" "Cancer enhanced" "Detected in all" "Leukemia: 186.8" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 16: Non-specific - RNA binding" Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Melanocytes: 31.3;Microglial cells: 27.4;Rod photoreceptor cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 44: Myeloma - Humoral immune response" "Cluster 64: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Non-specific - Antiviral immune response" "Cluster 66: Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 521.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in all" 8 "lymphoma: 193.4;Myeloma: 230.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" POU5F1 "MGC22487, OCT3, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.5;Glandular and luminal cells: 49.2" "Cancer enriched" "Detected in many" 34 "testis cancer: 355.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 19 "testis cancer: 287.4" "Not detected" "Not detected" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 14: Endometrium - Transcription regulation" Nucleoplasm Cytosol "CAB025600: , CAB026380: , CAB079773: AB_2687916, HPA058267: AB_2683659" "unprognostic (3.25e-2)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-2)" "unprognostic (2.11e-2)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.59e-1)" "unprognostic (9.27e-2)" "unprognostic (2.27e-2)" "unprognostic (4.79e-2)" "unprognostic (1.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.35e-1)" "unprognostic (3.86e-2)" "prognostic favorable (2.04e-5)" PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 165.1" "Cell type enhanced" "Detected in many" "Adipocytes: 241.5;Cytotrophoblasts: 116.0;Distal enterocytes: 103.7;Extravillous trophoblasts: 252.1;Granulosa cells: 219.1;Syncytiotrophoblasts: 109.0" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 247.6;Endothelial cells: 205.5;Excitatory neurons: 203.2;Oligodendrocytes: 191.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 66: Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001924: AB_1079665, HPA071162: " "unprognostic (5.27e-2)" "unprognostic (5.71e-2)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.94e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.11e-4)" "unprognostic (7.33e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.92e-2)" "prognostic favorable (5.11e-7)" "unprognostic (8.54e-2)" "unprognostic (7.54e-2)" "unprognostic (2.64e-1)" "unprognostic (4.09e-2)" PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: Non-specific - RNA binding" "Cluster 40: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" PRDM16 "KIAA1675, KMT8F, MEL1, MGC166915, PFM13" ENSG00000142611 "PR/SET domain 16" Q9HAZ2 1 3069168-3438621 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 16.2" "Cell type enriched" "Detected in many" 5 "Astrocytes: 168.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "NK-cell: 2.4" "Lineage enriched" "Detected in single" 16 "NK-cells: 2.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 4.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Skeletal muscle - Smooth muscle cells" "Region enriched" "Detected in many" 5 "basal ganglia: 15.7" "Low region specificity" "Detected in many" "HPA050343, HPA060467" Supported Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 63: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA050343: AB_2681099, HPA060467: AB_2684287" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (5.31e-4)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "unprognostic (3.95e-2)" "unprognostic (9.15e-3)" "unprognostic (5.68e-4)" "unprognostic (2.58e-1)" "unprognostic (2.07e-2)" "unprognostic (5.21e-2)" "unprognostic (1.71e-1)" "unprognostic (7.80e-6)" "unprognostic (2.14e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (4.06e-2)" PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 101.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 53: Non-specific - mRNA processing" "Cluster 75: Myeloid cells - Innate immune response" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 776.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: Skin cancer - Melanocyte processes" "Cluster 77: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 271.2;Endometrial stromal cells: 161.2;Fibroblasts: 216.2;Late spermatids: 410.5;Leydig cells: 267.6;Oligodendrocyte precursor cells: 276.3;Smooth muscle cells: 183.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 44.8;Rhabdoid: 66.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 65: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 292.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 41: Non-specific - Cilium assembly" "Cluster 64: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 879.3;Oligodendrocyte precursor cells: 299.9;Oligodendrocytes: 1206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 38: Neurons - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 628.6" "Cell type enhanced" "Detected in many" "Astrocytes: 1104.6;Oligodendrocyte precursor cells: 1360.8;Oligodendrocytes: 4317.6" "Cancer enriched" "Detected in all" 6 "glioma: 42.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 15: Non-specific - Protein binding" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB022602: , HPA019123: AB_1855980" "unprognostic (2.42e-1)" "unprognostic (5.81e-2)" "unprognostic (1.31e-1)" "unprognostic (1.06e-2)" "unprognostic (8.57e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.76e-3)" "unprognostic (1.08e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.16e-1)" "unprognostic (3.86e-1)" "unprognostic (4.09e-2)" RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 49: Non-specific - Unknown function" "Cluster 12: Non-specific - Chromatin organization" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Astrocytes: 146.1;Microglial cells: 256.3;Oligodendrocyte precursor cells: 150.7;Oligodendrocytes: 354.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 46: Non-specific - Unknown function" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" "Nuclear bodies" Nucleoplasm "CAB016191: AB_2238209, HPA051869: AB_2681644" "unprognostic (9.10e-3)" "unprognostic (5.45e-2)" "unprognostic (4.92e-1)" "unprognostic (6.65e-2)" "unprognostic (2.38e-2)" "unprognostic (4.85e-2)" "unprognostic (6.42e-3)" "unprognostic (2.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (6.80e-3)" "unprognostic (1.47e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.49e-2)" "unprognostic (6.79e-2)" "unprognostic (8.13e-3)" RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 5: Non-specific - Unknown function" "Cluster 17: Granulosa cells - Transcription regulation" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 315.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 45: Non-specific - Cell proliferation" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" RAP1GDS1 SmgGDS ENSG00000138698 "Rap1 GTPase-GDP dissociation stimulator 1" P52306 4 98261384-98443858 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.4" "Cell type enhanced" "Detected in all" "Early spermatids: 468.9;Inhibitory neurons: 172.3;Late spermatids: 280.1;Oligodendrocytes: 337.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019060 Approved Supported Cytosol NA NA 62000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 45: Non-specific - Cell proliferation" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Cytosol "HPA019060: AB_1856068" "unprognostic (8.12e-2)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-3)" "unprognostic (3.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (4.60e-1)" "prognostic favorable (2.00e-4)" "unprognostic (7.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 106.2;monocytes: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 65: Breast cancer - Unknown function" "Cluster 75: Myeloid cells - Innate immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: Non-specific - RNA binding" "Cluster 1: T-cells - Immune response" Nucleoplasm "CAB015201: , HPA019824: AB_1856113, HPA049642: AB_2680839" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (4.91e-2)" "unprognostic (9.67e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.37e-4)" "prognostic favorable (7.97e-4)" "unprognostic (2.88e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "dendritic cells: 48.0;Horizontal cells: 28.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 120.9;thyroid cancer: 39.8" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: TT & NCI-H1385 - Synaptic signal transduction" "Cluster 65: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Group enriched" "Detected in many" 6 "B-cells: 234.2;granulocytes: 305.0;NK-cells: 110.3;Plasma cells: 137.4;T-cells: 216.5" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Bone cancer: 37.0;Leukemia: 54.2;lymphoma: 77.1;Myeloma: 49.0" "Adipose visceral - T-cells, Liver - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 1: T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.3;Erythroid cells: 41.7;Peritubular cells: 44.6;Spermatocytes: 44.4;Spermatogonia: 53.5;Syncytiotrophoblasts: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 124.1" "Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 64: Lymphoma - Humoral immune response" "Cluster 28: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Immunity, Lipid metabolism, Ubl conjugation pathway" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 331.6;Exocrine glandular cells: 306.0;NK-cells: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 64: Non-specific - Transcription" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 8 "Alveolar cells type 2: 141.2" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.8" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 3: HUVEC & TIME - Signal transduction" "Cluster 41: Alveolar cells - Lung function" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6185020-6209389 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA068294 Approved Nucleoplasm,Nucleoli NA NA 860000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 57: Non-specific - Translation" "Cluster 39: Non-specific - Translation" Nucleoli Nucleoplasm "HPA068294: AB_2732781" "unprognostic (3.16e-3)" "unprognostic (1.28e-1)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-3)" "unprognostic (4.40e-2)" "unprognostic (7.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.48e-1)" "unprognostic (4.24e-2)" "unprognostic (1.46e-3)" "unprognostic (3.83e-1)" "unprognostic (3.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.98e-1)" RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 433.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 730000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 40: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB009748: AB_2182230, HPA026828: AB_10610418, HPA051520: AB_2681521" "unprognostic (4.83e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" "unprognostic (4.58e-3)" "unprognostic (2.87e-1)" "unprognostic (7.68e-2)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.74e-2)" RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 17 "Excitatory neurons: 74.3;Inhibitory neurons: 84.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.9;Rhabdoid: 6.2" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Testis - Spermatogonia" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Rabdoid cancer - Embryonic development" "Cluster 37: Neurons - Neuronal signaling" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 20.2;Endothelial cells: 18.7;Fibroblasts: 49.6;Inhibitory neurons: 17.3;Leydig cells: 27.9;Smooth muscle cells: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.2;Rhabdoid: 19.5" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 61: Liver - Metabolism" "Cluster 53: Connective tissue cells - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.6;Mucus glandular cells: 179.0;Salivary duct cells: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cancer enhanced" "Detected in many" "Leukemia: 98.3" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 73: Prostatic glandular cells - Transcription" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.3;Excitatory neurons: 194.0;Inhibitory neurons: 317.9;Microglial cells: 100.3;Oligodendrocyte precursor cells: 251.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.6;testis cancer: 7.8" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: Non-specific - Cilium assembly" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 580.4;Exocrine glandular cells: 797.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 74: Pancreatic cells - Mixed function" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" SET "2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA" ENSG00000119335 "SET nuclear proto-oncogene" Q01105 9 128683424-128696400 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005232, HPA063683" Supported Enhanced "Nucleoplasm,Lipid droplets" NA NA 880000 "Cluster 49: Eosinophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 55: Non-specific - Unknown function" "Cluster 16: Non-specific - RNA binding" Nucleoplasm "Lipid droplets" "CAB005232: AB_2185634, HPA063683: AB_2685088" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (2.31e-1)" "unprognostic (3.77e-1)" "unprognostic (7.15e-2)" "unprognostic (4.37e-3)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.00e-2)" "unprognostic (1.88e-2)" "unprognostic (3.62e-1)" "unprognostic (3.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (7.57e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (1.54e-2)" SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 343.9;Inhibitory neurons: 536.3;Oligodendrocyte precursor cells: 163.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cancer enhanced" "Detected in many" "Myeloma: 13.0" "Kidney - Fibroblasts, Lung - Fibroblast_1, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: Myeloma - Humoral immune response" "Cluster 37: Neurons - Neuronal signaling" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" SFPQ "PPP1R140, PSF" ENSG00000116560 "Splicing factor proline and glutamine rich" P23246 1 35176378-35193145 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009886, HPA047513, HPA054689" Enhanced Enhanced Nucleoplasm NA NA 640000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - mRNA processing" "Cluster 11: Non-specific - Transcription" Nucleoplasm "CAB009886: AB_2186937, HPA047513: AB_2680073, HPA054689: AB_2682574" "prognostic favorable (9.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (5.53e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (7.91e-13)" "unprognostic (3.10e-1)" "unprognostic (4.00e-3)" "unprognostic (3.85e-2)" "unprognostic (2.20e-2)" "unprognostic (8.03e-3)" "unprognostic (1.25e-3)" "unprognostic (1.16e-2)" "unprognostic (3.97e-3)" "unprognostic (3.07e-1)" "unprognostic (3.77e-3)" SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Enhanced Cytosol NA NA 390000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 53: Non-specific - mRNA processing" "Cluster 54: Extravillous trophoblasts - Unknown function" Cytosol "HPA021485: AB_1856816" "unprognostic (1.32e-1)" "prognostic favorable (1.50e-4)" "unprognostic (6.85e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.84e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.36e-8)" "unprognostic (5.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.02e-3)" "unprognostic (4.10e-2)" SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 680.0;Alveolar cells type 2: 1600.3" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 62.8;ovarian cancer: 124.8;pancreatic cancer: 59.5" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 41: Alveolar cells - Lung function" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Group enriched" "Detected in many" 6 "granulocytes: 111.0;Prostatic glandular cells: 438.6" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cancer enriched" "Detected in all" 6 "prostate cancer: 99.4" "Breast - Breast myoepithelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 62: Granulocytes - Innate immune response" "Cluster 73: Prostatic glandular cells - Transcription" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" SND1 "p100, TDRD11" ENSG00000197157 "Staphylococcal nuclease and tudor domain containing 1" Q7KZF4 7 127652194-128092609 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 247.0;Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002529, HPA002632, CAB019323" Enhanced Enhanced Cytosol NA NA 1800000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: Non-specific - Transcription" "Cluster 40: Plasma cells - Humoral immune response" Cytosol "CAB019323: , HPA002529: AB_1857317, HPA002632: AB_1857316" "unprognostic (2.06e-1)" "unprognostic (8.27e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.95e-4)" "unprognostic (5.10e-3)" "unprognostic (6.83e-2)" "unprognostic (1.17e-2)" "unprognostic (2.91e-2)" "unprognostic (4.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.42e-2)" "unprognostic (2.26e-3)" SRSF3 "SFRS3, SRp20" ENSG00000112081 "Serine and arginine rich splicing factor 3" P84103 6 36594353-36605600 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012986, HPA056981" Supported Supported Nucleoplasm NA NA 1600000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 53: Non-specific - mRNA processing" "Cluster 11: Non-specific - Transcription" Nucleoplasm "CAB012986: AB_2533150, HPA056981: AB_2683299" "unprognostic (3.25e-1)" "unprognostic (1.08e-3)" "prognostic favorable (2.56e-4)" "unprognostic (8.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.22e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.95e-4)" "prognostic favorable (1.37e-4)" "unprognostic (9.61e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (9.88e-2)" "unprognostic (3.33e-2)" "unprognostic (8.33e-2)" "unprognostic (1.06e-2)" SS18 "SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 51: Late spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA055741: AB_2682901, HPA059539: AB_2684055" "unprognostic (2.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.95e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "unprognostic (4.59e-2)" "unprognostic (1.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.40e-2)" "unprognostic (1.30e-1)" SS18L1 "CREST, KIAA0693" ENSG00000184402 "SS18L1 subunit of BAF chromatin remodeling complex" O75177 20 62143769-62182514 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011827, HPA059046" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 60: Proximal tubular cells - Absorption" "Nucleoplasm, Cytosol" "CAB011827: AB_778216, HPA059046: AB_2683888" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "prognostic favorable (8.00e-5)" "unprognostic (1.39e-1)" "prognostic favorable (3.74e-4)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (2.47e-3)" "unprognostic (6.43e-2)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (9.94e-3)" SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 6.8" "Group enriched" "Detected in some" 37 "Spermatocytes: 27.7;Spermatogonia: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 48.3" "Testis - Spermatocytes" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: Myeloma - Humoral immune response" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " "unprognostic (2.25e-1)" "unprognostic (3.51e-3)" "unprognostic (2.36e-1)" "unprognostic (4.32e-3)" "unprognostic (3.38e-1)" "unprognostic (5.41e-2)" "unprognostic (6.94e-2)" SSX2 "CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX" ENSG00000241476 "SSX family member 2" Q16385 X 52696896-52707189 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 15.0" "Cell type enriched" "Detected in single" 5 "Spermatogonia: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.1;prostate cancer: 5.6" "HPA045683, HPA071685" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 44: Myeloma - Humoral immune response" "Cluster 47: Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 8.9;Gastric cancer: 4.2;lymphoma: 9.4;Myeloma: 11.2;ovarian cancer: 4.7" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 44: Myeloma - Humoral immune response" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " STAT5B ENSG00000173757 "Signal transducer and activator of transcription 5B" P51692 17 42199177-42276707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 87.8;Late spermatids: 185.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004298, CAB005418, HPA042128, HPA049883, HPA051156" Approved Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 51: Late spermatids - Spermatogenesis" Cytosol "CAB004298: AB_2197067, CAB005418: AB_632445, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (4.06e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.68e-1)" "unprognostic (4.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (3.06e-2)" "unprognostic (7.98e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.36e-1)" "prognostic favorable (2.39e-5)" "unprognostic (9.19e-2)" "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 45: Non-specific - Cell proliferation" "Cluster 33: Macrophages - Degranulation" Cytosol Nucleoplasm "HPA001861: AB_1080106" "unprognostic (3.43e-3)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" "unprognostic (6.70e-2)" "unprognostic (1.88e-2)" "unprognostic (3.65e-1)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "prognostic favorable (7.76e-4)" "prognostic favorable (1.14e-4)" STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 12.2;Spermatocytes: 17.2;Spermatogonia: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028388 Approved Nucleoplasm,Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 38: Non-specific - mRNA processing" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Centrosome" "HPA028388: " "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 45: Non-specific - Cell proliferation" "Cluster 8: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoplasm "HPA017286: AB_1857618" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (3.57e-3)" "unprognostic (2.23e-2)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.63e-3)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.77e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (2.11e-1)" "unprognostic (3.43e-2)" SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 65: Breast cancer - Unknown function" "Cluster 43: Non-specific - Cell proliferation" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.0;dendritic cells: 122.3;Hofbauer cells: 80.8;Kupffer cells: 89.6;Macrophages: 105.2;Microglial cells: 111.3;monocytes: 85.4;Plasma cells: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 76.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 33: Macrophages - Degranulation" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" TAF15 "hTAFII68, Npl3, RBP56, TAF2N" ENSG00000270647 "TATA-box binding protein associated factor 15" Q92804 17 35713791-35864615 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052059, HPA063647" Supported Enhanced Nucleoplasm NA NA 44000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 65: Breast cancer - Unknown function" "Cluster 61: Non-specific - Transcription" Nucleoplasm "HPA052059: AB_2681711, HPA063647: AB_2685072" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (8.48e-3)" "unprognostic (4.75e-2)" "unprognostic (8.06e-3)" "unprognostic (2.08e-2)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (1.79e-2)" "unprognostic (1.39e-2)" "unprognostic (5.41e-2)" "unprognostic (3.35e-2)" "unprognostic (2.99e-1)" TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enhanced" "Detected in some" "Adipocytes: 24.0;Endothelial cells: 17.6;Erythroid cells: 82.7;granulocytes: 30.9;Late spermatids: 18.5;Microglial cells: 28.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Leukemia: 27.9" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: Myeloid leukemia - Oxygen transport" "Cluster 71: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" TAL2 bHLHa19 ENSG00000186051 "TAL bHLH transcription factor 2" Q16559 9 105662457-105663124 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 13.7" "Cell type enhanced" "Detected in some" "B-cells: 2.7;Cone photoreceptor cells: 8.6;Distal tubular cells: 12.4;Muller glia cells: 3.1;Proximal tubular cells: 3.2;Skeletal myocytes: 4.9" "Group enriched" "Detected in some" 4 "renal cancer: 1.6;testis cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 6.9;naive B-cell: 7.3" "Lineage enriched" "Detected in many" 4 "B-cells: 7.3" "Cancer enriched" "Detected in some" 27 "Rhabdoid: 35.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030886 Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 22: Rhabdoid cancers - Neuronal signaling" "Cluster 62: B-cells - B-cell activation" Cytosol "HPA030886: AB_10601596" "unprognostic (3.89e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "unprognostic (5.54e-2)" "unprognostic (2.24e-1)" "unprognostic (9.06e-2)" "unprognostic (4.98e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-3)" "unprognostic (2.63e-1)" "unprognostic (7.00e-4)" "unprognostic (2.84e-2)" "prognostic favorable (2.69e-4)" "unprognostic (2.70e-2)" "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (7.39e-2)" TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 62: B-cells - B-cell activation" Nucleoplasm Nucleoli "HPA043786: AB_10959468" "unprognostic (5.35e-2)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (2.11e-3)" "unprognostic (3.34e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (1.77e-1)" "unprognostic (4.14e-2)" "unprognostic (1.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.80e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 312.8;Microglial cells: 428.7;Oligodendrocyte precursor cells: 592.1;Oligodendrocytes: 1428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 41: Non-specific - Cilium assembly" "Cluster 8: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609290-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 55.3;Spermatogonia: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 40: Plasma cells - Humoral immune response" Nucleoplasm "CAB018351: AB_675504, HPA049808: AB_2680892, HPA062476: AB_2684775" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-2)" "unprognostic (8.25e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.07e-2)" "unprognostic (7.99e-2)" "unprognostic (2.35e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.87e-3)" "unprognostic (1.88e-1)" "unprognostic (3.07e-1)" "unprognostic (8.05e-2)" TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in all" "Astrocytes: 256.5;Extravillous trophoblasts: 274.3;monocytes: 232.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: Stomach & Colon cancer - Absorption" "Cluster 19: Macrophages - Innate immune response" "Nucleoplasm, Nuclear bodies" Cytosol "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 267.6" "Group enriched" "Detected in some" 6 "B-cells: 291.2;dendritic cells: 387.7" "Cancer enriched" "Detected in many" 18 "testis cancer: 64.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 296 "memory B-cell: 874.7;naive B-cell: 2160.3;plasmacytoid DC: 1099.9" "Group enriched" "Detected in all" 350 "B-cells: 2160.3;dendritic cells: 1099.9" "Group enriched" "Detected in some" 223 "Leukemia: 216.1;lymphoma: 458.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 23: B-cell cancers - Adaptive immune response" "Cluster 62: B-cells - B-cell activation" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: AB_2179419, HPA016604: AB_1857859" "unprognostic (1.27e-3)" "unprognostic (3.12e-4)" "unprognostic (2.61e-4)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (4.75e-4)" "unprognostic (7.70e-2)" "unprognostic (9.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-2)" "unprognostic (2.64e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (4.55e-1)" TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 52.8;Endometrial stromal cells: 45.1;Extravillous trophoblasts: 101.0;Oligodendrocyte precursor cells: 42.8;Oligodendrocytes: 42.8;Theca cells: 44.9" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.9" "Colon - Enteric glia cells, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 6: BEWO - Unknown function" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 48: Non-specific - RNA binding" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 91.9;Syncytiotrophoblasts: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 16.9;intermediate monocyte: 16.3;memory B-cell: 34.2;myeloid DC: 14.7;naive B-cell: 22.6;neutrophil: 47.4;non-classical monocyte: 14.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 41.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 9: Lymphoid cancers - Immune response" "Cluster 62: B-cells - B-cell activation" Cytosol "HPA067082: " "unprognostic (3.63e-3)" "unprognostic (1.51e-3)" "unprognostic (1.75e-2)" "unprognostic (4.48e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (4.22e-3)" "unprognostic (1.39e-2)" "unprognostic (4.13e-2)" "prognostic favorable (4.77e-4)" "unprognostic (2.12e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: Non-specific - Mitochondria" "Cluster 53: Connective tissue cells - ECM organization" Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" TLX1 "HOX11, TCL3" ENSG00000107807 "T cell leukemia homeobox 1" P31314 10 101131300-101137789 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "lymphoid tissue: 43.9;salivary gland: 16.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.4;Mucus glandular cells: 4.1;Salivary duct cells: 7.7;Suprabasal keratinocytes: 1.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling" "Cluster 22: Squamous epithelial cells - Keratinization" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.06e-5)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (5.07e-1)" "unprognostic (1.57e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.81e-1)" "unprognostic (2.63e-1)" "unprognostic (3.26e-1)" "unprognostic (3.06e-1)" "unprognostic (7.35e-2)" TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "brain: 9.0" "Cell type enriched" "Detected in single" 20 "Extravillous trophoblasts: 9.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.7" "Group enriched" "Detected in many" 6 "cerebellum: 9.0;medulla oblongata: 2.3;spinal cord: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.0" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 8 "cerebellum: 15.5" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: Lymphoid cancers - Adaptive immune response" "Cluster 54: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA030504: AB_2732458, HPA060957: AB_2732655, HPA069359: AB_2732130" "unprognostic (3.52e-2)" "unprognostic (2.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (2.76e-2)" "unprognostic (4.48e-2)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.6;Gastric mucus-secreting cells: 172.9;Paneth cells: 149.4;Prostatic glandular cells: 377.5;Proximal enterocytes: 170.9" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 271.4" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 24: Prostate cancer - Lipid metabolism" "Cluster 50: Enterocytes - Absorption" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 15 "Plasma cells: 468.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cancer enriched" "Detected in some" 12 "Myeloma: 633.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: Myeloma - Humoral immune response" "Cluster 45: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 907.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Ovarian cancer RMG-I - Cellular stress response" "Cluster 67: Syncytiotrophoblasts - Pregnancy" "Nucleoplasm, Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 49: Non-specific - Unknown function" "Cluster 39: Non-specific - Translation" Nucleoplasm "Vesicles, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Basal squamous epithelial cells: 251.1;Skeletal myocytes: 81.2;Squamous epithelial cells: 157.7;Suprabasal keratinocytes: 189.8" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 110.8;Gallbladder cancer: 189.5;head and neck cancer: 118.7" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 60: Keratinocytes - Epithelial cell function" "Cluster 22: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Cell type enhanced" "Detected in all" "monocytes: 1100.0;Skeletal myocytes: 933.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: Non-specific - RNA binding" "Cluster 74: Pancreatic cells - Mixed function" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: Connective tissue cells - ECM organization" "Cluster 15: Smooth muscle cells - Muscle contraction" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" TPR ENSG00000047410 "Translocated promoter region, nuclear basket protein" P12270 1 186311652-186375693 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 757.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019661, HPA019663, HPA024336" Enhanced Enhanced "Nuclear membrane" NA NA 30000000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: Non-specific - RNA binding" "Cluster 31: Spermatocytes - Spermatogenesis" "Nuclear membrane" "HPA019661: AB_1858215, HPA019663: AB_1858216, HPA024336: AB_1858217" "unprognostic (4.51e-2)" "unprognostic (9.87e-3)" "unprognostic (2.48e-1)" "unprognostic (7.56e-2)" "unprognostic (9.88e-3)" "prognostic favorable (4.71e-4)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.71e-1)" "unprognostic (3.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-2)" "unprognostic (3.63e-2)" "unprognostic (1.31e-3)" "unprognostic (3.75e-1)" "unprognostic (4.19e-2)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 62: Granulocytes - Innate immune response" "Cluster 17: Granulosa cells - Transcription regulation" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923988 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: Myeloma - Humoral immune response" "Cluster 40: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA048684: AB_2680493, HPA053408: AB_2682139" "unprognostic (1.57e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.01e-2)" "unprognostic (1.12e-3)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (3.50e-6)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "prognostic favorable (2.71e-4)" TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392790-114511203 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 272.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 38: Non-specific - mRNA processing" "Cluster 57: Early spermatids - Flagellum & Golgi organization" Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favorable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002570 Supported Supported "Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 46: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Golgi apparatus" "HPA002570: AB_1078995" "unprognostic (1.65e-1)" "unprognostic (2.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "prognostic favorable (1.78e-6)" "unprognostic (1.78e-1)" "unprognostic (5.08e-1)" "unprognostic (7.74e-2)" "unprognostic (5.55e-2)" USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in some" "Early spermatids: 19.8;Late spermatids: 14.7;Skeletal myocytes: 20.8;Spermatocytes: 20.0" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 47: Retina - Visual perception" "Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" WDCP "C2orf44, FLJ21945, MMAP" ENSG00000163026 "WD repeat and coiled coil containing" Q9H6R7 2 24029347-24049575 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041054 Approved Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 45: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" Nucleoli Cytosol "HPA041054: AB_10796566" "unprognostic (1.07e-1)" "unprognostic (3.19e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (5.14e-8)" "unprognostic (7.69e-2)" "unprognostic (9.01e-3)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (7.76e-2)" "unprognostic (3.00e-1)" WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 12 "Muller glia cells: 2340.6" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Rhabdoid: 16.0;Uterine cancer: 22.4" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 2: DU4475 - Unknown function" "Cluster 68: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 29.5;Endometrial stromal cells: 81.6;Sertoli cells: 135.4;Thymic epithelial cells: 80.7" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 10.0" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: Ovarian & Endometrial cancers - Unknown function" "Cluster 52: Endometrial stromal cells - ECM organization" Nucleoplasm Cytosol "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endothelial cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Skin cancer - Membrane components" "Cluster 66: Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 49: Non-specific - Unknown function" "Cluster 18: Non-specific - Mixed function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.1;Prostatic glandular cells: 331.8;Skeletal myocytes: 429.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Group enriched" "Detected in some" 5 "Leukemia: 10.0;prostate cancer: 16.2" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 65: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" ZMYM2 "FIM, MYM, RAMP, ZNF198" ENSG00000121741 "Zinc finger MYM-type containing 2" Q9UBW7 13 19958677-20091829 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031765 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 13: Non-specific - Nuclear processes" "Cluster 48: Plasmacytoid dendritic cells - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA031765: AB_10601927" "unprognostic (2.96e-1)" "unprognostic (3.42e-3)" "unprognostic (1.85e-1)" "unprognostic (1.69e-1)" "unprognostic (7.71e-2)" "unprognostic (2.33e-1)" "unprognostic (2.66e-3)" "unprognostic (1.16e-1)" "unprognostic (6.78e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (2.80e-2)" "unprognostic (6.65e-3)" "unprognostic (2.05e-1)" "unprognostic (8.74e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.07e-4)" ZNF331 "RITA, ZNF361, ZNF463" ENSG00000130844 "Zinc finger protein 331" Q9NQX6 19 53519527-53580269 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 482.7;granulocytes: 876.8;Langerhans cells: 288.9;T-cells: 327.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063157 Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Non-specific - Transcription" "Cluster 1: T-cells - Immune response" Nucleoplasm "HPA063157: AB_2684951" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-2)" "unprognostic (4.24e-1)" "unprognostic (8.16e-2)" "unprognostic (7.62e-3)" "unprognostic (3.25e-2)" "unprognostic (1.84e-2)" "unprognostic (4.40e-2)" "unprognostic (5.68e-3)" "unprognostic (2.69e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (6.74e-2)" ZNF384 "CAGH1A, CIZ, NMP4, NP, TNRC1" ENSG00000126746 "Zinc finger protein 384" Q8TF68 12 6666477-6689572 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004051 Supported Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 45: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" Nucleoplasm "HPA004051: AB_1859228" "unprognostic (1.90e-1)" "unprognostic (5.11e-3)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (3.04e-2)" "unprognostic (1.87e-2)" "unprognostic (9.94e-2)" "unprognostic (1.35e-2)" "unprognostic (2.57e-2)" "unprognostic (3.51e-2)" "unprognostic (4.25e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (8.13e-2)" ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 164.8;Microglial cells: 52.0;Oligodendrocyte precursor cells: 212.3;Oligodendrocytes: 98.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cancer enhanced" "Detected in many" "Leukemia: 16.7;Rhabdoid: 26.6" "Lung - Fibroblast_2, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 66: Myeloid cells - Innate immune response" "Cluster 10: Neurons & Oligodendrocytes - Nervous system development" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)"